| Probe |
Symbol |
Description |
Chromosome |
Chromosome Location |
GenBank |
Gene |
PubMed |
Gene Ontology |
Pathway |
| 1436530_at |
Wfdc17 |
WAP four-disulfide core domain 17 |
11 |
83704055 |
AA666504 |
100034251 |
7 |
serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity extracellular space antibacterial humoral response innate immune response |
|
| 1457728_at |
Niban3 |
niban apoptosis regulator 3 |
8 |
71597707 |
BB763642 |
100037278 |
11 |
molecular_function cellular_component biological_process |
|
| 1446929_at |
D130062J21Rik |
RIKEN cDNA D130062J21 gene |
4 |
|
BB459664 |
100038651 |
9 |
molecular_function cellular_component biological_process |
|
| 1426113_x_at |
Trav9d-3 |
T cell receptor alpha variable 9D-3 |
14 |
|
U07662 |
100038850 |
10 |
molecular_function cellular_component biological_process |
|
| 1436040_at |
Snhg12 |
small nucleolar RNA host gene 12 |
4 |
132308677 |
BI180630 |
100039864 |
26 |
molecular_function cellular_component biological_process |
|
| 1456765_at |
Nhsl2 |
NHS like 2 |
X |
101849384 |
AV339861 |
100042480 |
12 |
molecular_function cellular_component cell differentiation |
|
| 1428562_at |
Mir22hg |
Mir22 host gene (non-protein coding) |
11 |
75461538 |
AK008813 |
100042498 |
16 |
response to wounding |
|
| 1440451_at |
Ankrd66 |
ankyrin repeat domain 66 |
17 |
-43534173 |
BG085035 |
100043332 |
10 |
molecular_function cellular_component biological_process |
|
| 1426168_a_at |
Trac |
T cell receptor alpha constant |
14 |
|
U95921 |
100101484 |
53 |
plasma membrane response to bacterium signaling receptor activity alpha-beta T cell receptor complex |
|
| 1426716_at |
Tdrd7 |
tudor domain containing 7 |
4 |
45965334, 45972296, 45972830 |
BC025099 |
100121 |
30 |
lens morphogenesis in camera-type eye lens morphogenesis in camera-type eye lens morphogenesis in camera-type eye RNA binding mRNA binding protein binding cytoplasm multicellular organism development germ cell development spermatogenesis spermatogenesis post-transcriptional regulation of gene expression cell differentiation P granule organization chromatoid body piRNA processing ribonucleoprotein granule P granule P granule lens fiber cell differentiation lens fiber cell differentiation lens fiber cell differentiation ribonucleoprotein complex |
|
| 1427765_a_at |
Trbv14 |
T cell receptor beta, variable 14 |
6 |
|
M31648 |
100124678 |
14 |
plasma membrane cell surface receptor signaling pathway |
|
| 1427752_a_at |
Trbv29 |
T cell receptor beta, variable 29 |
6 |
|
U63547 |
100124698 |
14 |
plasma membrane cell surface receptor signaling pathway peptide antigen binding |
|
| 1433735_a_at |
Tmem64 |
transmembrane protein 64 |
4 |
15265819 |
BG075363 |
100201 |
22 |
protein binding endoplasmic reticulum endoplasmic reticulum membrane osteoclast differentiation regulation of ATP-dependent activity positive regulation of fat cell differentiation negative regulation of osteoblast differentiation positive regulation of osteoclast differentiation positive regulation of osteoclast differentiation positive regulation of bone resorption positive regulation of bone resorption regulation of cytosolic calcium ion concentration regulation of cytosolic calcium ion concentration negative regulation of canonical Wnt signaling pathway |
|
| 1417300_at |
Smpdl3b |
sphingomyelin phosphodiesterase, acid-like 3B |
4 |
-132732965 |
NM_133888 |
100340 |
28 |
immune system process sphingomyelin phosphodiesterase activity protein binding extracellular region extracellular space extracellular space plasma membrane lipid metabolic process sphingomyelin catabolic process inflammatory response phosphoric diester hydrolase activity phosphoric diester hydrolase activity phosphoric diester hydrolase activity phosphoric diester hydrolase activity metabolic process zinc ion binding membrane lipid catabolic process hydrolase activity hydrolase activity, acting on glycosyl bonds negative regulation of toll-like receptor signaling pathway innate immune response negative regulation of innate immune response membrane lipid catabolic process metal ion binding negative regulation of inflammatory response side of membrane |
|
| 1456393_at |
Bbip1 |
BBSome interacting protein 1 |
19 |
-53929658 |
AI642124 |
100503572 |
20 |
molecular_function cytoplasm BBSome BBSome eating behavior ciliary membrane cilium assembly cilium assembly receptor localization to non-motile cilium receptor localization to non-motile cilium |
|
| 1440967_at |
Gm15708 |
predicted gene 15708 |
5 |
144277060 |
AI666381 |
100504231 |
8 |
molecular_function cellular_component biological_process |
|
| 1422892_s_at |
H2-Ea |
histocompatibility 2, class II antigen E alpha |
17 |
-34341951 |
U13648 |
100504404 |
69 |
immunological synapse positive regulation of T cell mediated cytotoxicity myeloid dendritic cell antigen processing and presentation antigen processing and presentation of endogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex peptide antigen assembly with MHC class II protein complex antigen processing and presentation of peptide or polysaccharide antigen via MHC class II lysosome lysosomal membrane lysosomal membrane plasma membrane external side of plasma membrane cell surface immunoglobulin mediated immune response immunoglobulin mediated immune response antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding polysaccharide binding late endosome membrane late endosome membrane positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation peptide antigen binding peptide antigen binding T cell receptor binding MHC class II protein complex MHC class II protein complex positive regulation of memory T cell differentiation regulation of T-helper cell differentiation positive regulation of immune response positive regulation of immune response positive regulation of immune response positive regulation of T cell activation cognition positive regulation of CD4-positive, alpha-beta T cell activation |
|
| 1420342_at |
Gdap10 |
ganglioside-induced differentiation-associated-protein 10 |
12 |
32824115 |
NM_010268 |
100504486 |
5 |
molecular_function cellular_component response to bacterium |
|
| 1430622_at |
4833423F13Rik |
RIKEN cDNA 4833423F13 gene |
16 |
|
AW764291 |
100504504 |
7 |
molecular_function cellular_component biological_process |
|
| 1438676_at |
Gbp6 |
guanylate binding protein 6 |
5 |
-105270701 |
BM241485 |
100702 |
17 |
nucleotide binding immune system process GTPase activity GTPase activity GTP binding GTP binding response to bacterium hydrolase activity symbiont-containing vacuole membrane cytoplasmic vesicle cytoplasmic vesicle cellular response to interferon-beta defense response to protozoan defense response to protozoan adhesion of symbiont to host innate immune response defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium cellular response to lipopolysaccharide cellular response to type II interferon cellular response to type II interferon |
|
| 1416414_at |
Emilin1 |
elastin microfibril interfacer 1 |
5 |
30913785 |
NM_133918 |
100952 |
61 |
aortic valve morphogenesis protein binding extracellular region extracellular region collagen trimer extracellular space extracellular space cell adhesion cell-matrix adhesion regulation of blood pressure positive regulation of gene expression negative regulation of gene expression positive regulation of cell-substrate adhesion cell migration negative regulation of angiogenesis extracellular matrix constituent conferring elasticity extracellular matrix constituent conferring elasticity extracellular matrix constituent conferring elasticity extracellular matrix organization negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of vascular endothelial growth factor receptor signaling pathway extracellular matrix negative regulation of collagen biosynthetic process cell adhesion mediated by integrin integrin alpha4-beta1 complex regulation of cell population proliferation identical protein binding identical protein binding positive regulation of angiogenesis elastic fiber assembly negative regulation of cell activation molecular adaptor activity negative regulation of SMAD protein signal transduction collagen-containing extracellular matrix collagen-containing extracellular matrix collagen-containing extracellular matrix negative regulation of ERK1 and ERK2 cascade integrin binding involved in cell-matrix adhesion positive regulation of defense response to bacterium negative regulation of vascular endothelial growth factor signaling pathway positive regulation of extracellular matrix assembly negative regulation of collagen fibril organization negative regulation of macrophage migration EMILIN complex |
|
| 1418201_at |
Plekhg2 |
pleckstrin homology domain containing, family G (with RhoGef domain) member 2 |
7 |
-28359603 |
NM_138752 |
101497 |
19 |
guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity regulation of actin filament polymerization regulation of actin filament polymerization small GTPase binding |
|
| 1434333_a_at |
Prkd2 |
protein kinase D2 |
7 |
16843064, 16842901 |
AW557946 |
101540 |
44 |
nucleotide binding angiogenesis positive regulation of endothelial cell proliferation adaptive immune response immune system process protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity diacylglycerol-dependent serine/threonine kinase activity protein kinase C binding ATP binding nucleus nucleoplasm cytoplasm Golgi apparatus cytosol cytosol plasma membrane protein phosphorylation cell adhesion phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of endothelial cell migration membrane kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation positive regulation of vascular endothelial growth factor receptor signaling pathway positive regulation of interleukin-2 production positive regulation of interleukin-8 production intracellular signal transduction intracellular signal transduction cellular response to vascular endothelial growth factor stimulus positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway positive regulation of blood vessel endothelial cell migration positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of angiogenesis positive regulation of cell adhesion positive regulation of transcription by RNA polymerase II protein autophosphorylation metal ion binding vascular endothelial growth factor receptor signaling pathway T cell receptor signaling pathway positive regulation of T cell receptor signaling pathway positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity regulation of T cell apoptotic process positive regulation of ERK1 and ERK2 cascade protein serine kinase activity positive regulation of intracellular signal transduction positive regulation of DNA biosynthetic process positive regulation of endothelial cell chemotaxis |
|
| 1423975_s_at |
Numa1 |
nuclear mitotic apparatus protein 1 |
7 |
101969842 |
BC006631 |
101706 |
63 |
establishment of mitotic spindle orientation establishment of mitotic spindle orientation establishment of mitotic spindle orientation spindle pole spindle pole microtubule bundle formation protein binding nucleus nucleoplasm chromosome cytoplasm centrosome centrosome cytosol cytoskeleton microtubule spindle microtubule spindle microtubule plasma membrane cell cortex cell cycle chromosome segregation microtubule binding microtubule binding lipid binding tubulin binding membrane nuclear matrix nuclear matrix protein domain specific binding dendrite positive regulation of BMP signaling pathway astral microtubule organization positive regulation of microtubule polymerization spindle pole centrosome positive regulation of intracellular transport protein-containing complex phosphatidylinositol binding microtubule plus-end microtubule minus-end neuronal cell body protein-containing complex binding apical part of cell positive regulation of keratinocyte differentiation microtubule plus-end binding microtubule minus-end binding cell division positive regulation of hair follicle development positive regulation of chromosome segregation cortical microtubule anastral spindle assembly regulation of mitotic spindle organization lung epithelial cell differentiation mitotic spindle astral microtubule dynein complex binding mitotic spindle regulation of metaphase plate congression microtubule bundle mitotic spindle pole mitotic spindle pole lateral cell cortex disordered domain specific binding cell cortex region cell cortex region positive regulation of protein localization to spindle pole body positive regulation of mitotic spindle elongation positive regulation of protein localization to cell cortex cytoplasmic microtubule bundle positive regulation of chromosome separation positive regulation of spindle assembly mitotic spindle midzone |
|
| 1460403_at |
Psip1 |
PC4 and SFRS1 interacting protein 1 |
4 |
-83461878, -83455680 |
BF117241 |
101739 |
44 |
mRNA 5'-splice site recognition euchromatin heterochromatin DNA binding chromatin binding transcription coactivator activity nucleus nucleus nucleoplasm chromatin remodeling response to oxidative stress response to heat nuclear periphery positive regulation of transcription by RNA polymerase II supercoiled DNA binding DNA-binding transcription factor binding |
|
| 1423806_at |
Ints4 |
integrator complex subunit 4 |
7 |
97480955 |
BC013813 |
101861 |
24 |
molecular_function nucleus nucleolus snRNA processing snRNA processing integrator complex integrator complex |
|
| 1430075_at |
Sf3b3 |
splicing factor 3b, subunit 3 |
8 |
-110810491 |
AK017529 |
101943 |
38 |
SAGA complex mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding protein binding nucleus nucleus nucleoplasm spliceosomal complex U2-type spliceosomal complex U2 snRNP U12-type spliceosomal complex nucleolus regulation of DNA repair mRNA processing RNA splicing U2 snRNA binding negative regulation of protein catabolic process regulation of RNA splicing protein-containing complex binding positive regulation of DNA-templated transcription U2-type precatalytic spliceosome catalytic step 2 spliceosome |
03040 |
| 1418553_at |
Arhgef18 |
Rho/Rac guanine nucleotide exchange factor 18 |
8 |
3393007, 3353436 |
NM_133962 |
102098 |
35 |
guanyl-nucleotide exchange factor activity cytoplasm cytosol cytoskeleton plasma membrane plasma membrane small GTPase-mediated signal transduction regulation of cell shape membrane actin cytoskeleton organization regulation of Rho protein signal transduction apical part of cell metal ion binding negative regulation of stress fiber assembly protein localization to cell-cell junction |
|
| 1436501_at |
Mtus1 |
mitochondrial tumor suppressor 1 |
8 |
-40990911, -40990911, -40990911, -40990911 |
BB747681 |
102103 |
30 |
nucleus nucleus nucleolus cytoplasm mitochondrion Golgi apparatus plasma membrane cell cycle microtubule binding regulation of macrophage chemotaxis regulation of macrophage chemotaxis microtubule cytoskeleton membrane |
|
| 1416065_a_at |
Ankrd10 |
ankyrin repeat domain 10 |
8 |
-11613840, -11611580, -11613840 |
NM_133971 |
102334 |
20 |
molecular_function nucleoplasm |
|
| 1416210_at |
Imp3 |
IMP3, U3 small nucleolar ribonucleoprotein |
9 |
56937499 |
NM_133976 |
102462 |
21 |
RNA binding structural constituent of ribosome nucleus nucleoplasm nucleolus rRNA processing rRNA processing small ribosomal subunit rRNA binding snoRNA binding preribosome small-subunit processome small-subunit processome Mpp10 complex Mpp10 complex ribosome biogenesis ribosomal small subunit biogenesis ribosomal small subunit biogenesis ribonucleoprotein complex |
03008 |
| 1458206_at |
Gm30054 |
predicted gene, 30054 |
14 |
|
BB201845 |
102631812 |
|
|
|
| 1441589_at |
Gm38448 |
predicted gene, 38448 |
11 |
|
BB634277 |
102632682 |
7 |
|
|
| 1430479_at |
Gm32819 |
predicted gene, 32819 |
9 |
|
AK008147 |
102635498 |
8 |
|
|
| 1451190_a_at |
Sbk1 |
SH3-binding kinase 1 |
7 |
126272495, 126248396 |
BC025837 |
104175 |
25 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding cellular_component cytoplasm protein phosphorylation kinase activity phosphorylation transferase activity |
|
| 1428750_at |
Cdc42ep2 |
CDC42 effector protein 2 |
19 |
-5917555 |
BF453885 |
104252 |
20 |
opioid peptide activity GTPase activator activity cytoplasm cytoplasm cytosol cytoskeleton cytoskeleton plasma membrane plasma membrane Rho protein signal transduction regulation of cell shape regulation of cell shape microtubule cytoskeleton membrane actin cytoskeleton organization positive regulation of actin filament polymerization positive regulation of actin filament polymerization small GTPase binding small GTPase binding positive regulation of pseudopodium assembly positive regulation of pseudopodium assembly phagocytic vesicle cellular response to type II interferon |
|
| 1455643_s_at |
Tsr1 |
TSR1 20S rRNA accumulation |
11 |
74898079 |
BF228294 |
104662 |
25 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GTPase activity GTP binding nucleus preribosome, small subunit precursor U3 snoRNA binding ribosome biogenesis |
|
| 1437956_at |
Pik3r6 |
phosphoinositide-3-kinase regulatory subunit 5 |
11 |
68503018 |
AV281292 |
104709 |
31 |
angiogenesis protein binding cytoplasm plasma membrane phosphatidylinositol 3-kinase complex phosphatidylinositol 3-kinase complex, class IA phosphatidylinositol 3-kinase complex, class IB G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway membrane regulation of natural killer cell mediated cytotoxicity positive regulation of MAP kinase activity positive regulation of MAP kinase activity positive regulation of T cell differentiation positive regulation of angiogenesis 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity 1-phosphatidylinositol-3-kinase regulator activity 1-phosphatidylinositol-3-kinase regulator activity |
|
| 1448104_at |
Aldh6a1 |
aldehyde dehydrogenase family 6, subfamily A1 |
12 |
-84430720, -84430720 |
NM_134042 |
104776 |
26 |
methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity nucleoplasm mitochondrion mitochondrion mitochondrion thymine catabolic process thymine catabolic process valine metabolic process valine catabolic process valine catabolic process oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor thiolester hydrolase activity beta-alanine catabolic process thymine metabolic process brown fat cell differentiation |
00280 00562 00640 01100 |
| 1453864_at |
Rdh14 |
retinol dehydrogenase 14 (all-trans and 9-cis) |
12 |
10390779 |
AK014097 |
105014 |
21 |
nucleoplasm mitochondrion endoplasmic reticulum cytosol lipid metabolic process alcohol dehydrogenase (NADP+) activity oxidoreductase activity retinol metabolic process NADP-retinol dehydrogenase activity NADP-retinol dehydrogenase activity |
|
| 1418772_at |
Tasor2 |
transcription activation suppressor family member 2 |
13 |
-3566034 |
NM_134063 |
105203 |
19 |
molecular_function nucleoplasm nucleoplasm cytosol biological_process negative regulation of gene expression, epigenetic |
|
| 1423746_at |
Txndc5 |
thioredoxin domain containing 5 |
13 |
-38500270, -38500270, -38500270 |
BC016252 |
105245 |
52 |
protein disulfide isomerase activity protein disulfide isomerase activity endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum lumen protein folding protein-disulfide reductase activity oxidoreductase activity isomerase activity |
04141 |
| 1424824_at |
Slain1 |
SLAIN motif family, member 1 |
14 |
103650227 |
BB704967 |
105439 |
17 |
molecular_function cytoplasm cytoskeleton microtubule nucleation positive regulation of microtubule polymerization cytoplasmic microtubule organization microtubule plus-end |
|
| 1426459_s_at |
Rimoc1 |
RAB7A interacting MON1-CCZ1 complex subunit 1 |
15 |
-3982034 |
BG073457 |
106064 |
14 |
mitophagy molecular_function nucleoplasm cytoplasm cytosol autophagy |
|
| 1451199_at |
Qtrt2 |
queuine tRNA-ribosyltransferase accessory subunit 2 |
16 |
-43861412 |
BC017628 |
106248 |
18 |
tRNA binding protein binding cytoplasm mitochondrion mitochondrial outer membrane tRNA modification tRNA processing zinc ion binding tRNA-guanosine(34) queuine transglycosylase activity membrane pentosyltransferase activity protein-containing complex protein-containing complex protein homodimerization activity metal ion binding protein heterodimerization activity tRNA-guanine transglycosylation tRNA-guanine transglycosylation tRNA-guanine transglycosylation transferase complex |
|
| 1448722_s_at |
Ppcs |
phosphopantothenoylcysteine synthetase |
4 |
-119418526 |
NM_026494 |
106564 |
19 |
nucleotide binding heart process phosphopantothenate--cysteine ligase activity phosphopantothenate--cysteine ligase activity ATP binding nucleus cytoplasm acetyl-CoA biosynthetic process coenzyme A biosynthetic process coenzyme A biosynthetic process ligase activity identical protein binding protein homodimerization activity |
00770 01100 |
| 1416165_at |
Rab31 |
RAB31, member RAS oncogene family |
17 |
-65651725 |
NM_133685 |
106572 |
26 |
nucleotide binding phagocytic cup GTPase activity GTPase activity protein binding GTP binding cytoplasm endosome early endosome late endosome Golgi apparatus trans-Golgi network intracellular protein transport endomembrane system membrane GDP binding cytoplasmic vesicle receptor internalization trans-Golgi network membrane trans-Golgi network membrane cellular response to insulin stimulus early phagosome membrane Golgi to plasma membrane protein transport Golgi to plasma membrane protein transport regulated exocytosis phagocytic vesicle Golgi vesicle transport positive regulation of phagocytosis, engulfment phagosome maturation |
04144 |
| 1417971_at |
Nrm |
nurim (nuclear envelope membrane protein) |
17 |
35861317 |
NM_134122 |
106582 |
20 |
molecular_function nucleus nuclear envelope nuclear inner membrane nuclear lamina biological_process membrane nuclear membrane nuclear membrane |
|
| 1428736_at |
Gramd2b |
GRAM domain containing 2B |
18 |
56432131, 56400339 |
AV259880 |
107022 |
16 |
molecular_function cytoplasmic microtubule cytoplasmic microtubule biological_process identical protein binding |
|
| 1427146_at |
Carns1 |
carnosine synthase 1 |
19 |
-4164323 |
BB356222 |
107239 |
16 |
nucleotide binding ATP binding cellular_component ligase activity ATP hydrolysis activity ATP hydrolysis activity ATP hydrolysis activity carnosine biosynthetic process carnosine biosynthetic process carnosine biosynthetic process metal ion binding carnosine synthase activity carnosine synthase activity carnosine synthase activity homocarnosine synthase activity homocarnosine synthase activity homocarnosine synthase activity |
|
| 1434372_at |
AW112010 |
expressed sequence AW112010 |
19 |
-11047611 |
BE688358 |
107350 |
10 |
molecular_function cellular_component biological_process |
|
| 1425927_a_at |
Atf5 |
activating transcription factor 5 |
7 |
-44812255, -44812255 |
AF375476 |
107503 |
66 |
transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding chromatin binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex cytoplasm centrosome cytosol cytoskeleton regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II circadian rhythm negative regulation of cell population proliferation post-embryonic development regulation of gene expression tubulin binding kinase binding olfactory bulb interneuron differentiation olfactory bulb interneuron development cerebellar granule cell precursor proliferation olfactory lobe development heat shock protein binding multicellular organism growth negative regulation of apoptotic process negative regulation of apoptotic process sequence-specific DNA binding sequence-specific DNA binding fat cell differentiation fat cell differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of centrosome cycle negative regulation of astrocyte differentiation negative regulation of neurogenesis RNA polymerase II transcription regulator complex negative regulation of cell cycle G2/M phase transition |
|
| 1424375_s_at |
Gimap4 |
GTPase, IMAP family member 4 |
6 |
48684577 |
BC005577 |
107526 |
22 |
nucleotide binding GTP binding cytoplasm cytosol cytosol intracellular membrane-bounded organelle |
|
| 1452367_at |
Coro2a |
coronin, actin binding protein 2A |
4 |
-46536936, -46536936 |
AI316747 |
107684 |
22 |
actin binding brush border transcription repressor complex actin filament binding |
|
| 1432492_a_at |
Haao |
3-hydroxyanthranilate 3,4-dioxygenase |
17 |
-83831353 |
AK002295 |
107766 |
24 |
3-hydroxyanthranilate 3,4-dioxygenase activity 3-hydroxyanthranilate 3,4-dioxygenase activity 3-hydroxyanthranilate 3,4-dioxygenase activity iron ion binding cytoplasm cytoplasm cytosol ferrous iron binding NAD biosynthetic process response to zinc ion oxidoreductase activity pyridine nucleotide biosynthetic process quinolinate biosynthetic process oxygen binding mitochondrial membrane 'de novo' NAD biosynthetic process from tryptophan response to cadmium ion metal ion binding quinolinate metabolic process quinolinate metabolic process dioxygenase activity neuron cellular homeostasis |
00380 01100 |
| 1426775_s_at |
Scamp1 |
secretory carrier membrane protein 1 |
13 |
-94201309, -94201432 |
BM115445 |
107767 |
26 |
protein binding endosome Golgi apparatus trans-Golgi network exocytosis endocytosis synaptic vesicle protein transport protein transport membrane protein domain specific binding clathrin-coated vesicle cytoplasmic vesicle membrane synaptic vesicle membrane synaptic vesicle membrane trans-Golgi network membrane zymogen granule membrane synapse establishment of localization in cell recycling endosome membrane recycling endosome membrane |
|
| 1428669_at |
Bmyc |
brain expressed myelocytomatosis oncogene |
2 |
25706878 |
AK012810 |
107771 |
31 |
G1/S transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II MAPK cascade chromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific core promoter sequence-specific DNA binding transcription coregulator binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity nucleus nucleoplasm nucleolus spindle chromatin remodeling DNA methylation-dependent heterochromatin formation regulation of DNA-templated transcription intracellular iron ion homeostasis DNA damage response response to gamma radiation regulation of cell cycle process positive regulation of gene expression regulation of telomere maintenance protein-DNA complex disassembly protein-containing complex identical protein binding positive regulation of cysteine-type endopeptidase activity involved in apoptotic process protein-containing complex binding negative regulation of monocyte differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of fibroblast proliferation negative regulation of fibroblast proliferation positive regulation of epithelial cell proliferation chromosome organization negative regulation of cell division molecular adaptor activity negative regulation of transcription initiation by RNA polymerase II ERK1 and ERK2 cascade E-box binding cellular response to hypoxia cellular response to xenobiotic stimulus Myc-Max complex RNA polymerase II transcription repressor complex DNA-binding transcription factor binding positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of miRNA transcription SCF ubiquitin ligase complex binding |
|
| 1425706_a_at |
Ddb2 |
damage specific DNA binding protein 2 |
2 |
-91211581, -91211580 |
AY027937 |
107986 |
35 |
protein polyubiquitination DNA binding damaged DNA binding damaged DNA binding ubiquitin-protein transferase activity nucleus nucleus nucleus nucleoplasm chromosome DNA repair DNA repair nucleotide-excision repair pyrimidine dimer repair DNA damage response DNA damage response response to UV response to UV cell junction Cul4A-RING E3 ubiquitin ligase complex Cul4A-RING E3 ubiquitin ligase complex Cul4B-RING E3 ubiquitin ligase complex protein-containing complex cellular response to UV cellular response to UV protein-containing complex binding protein autoubiquitination UV-damage excision repair Cul4-RING E3 ubiquitin ligase complex site of DNA damage |
03420 04115 04120 |
| 1427860_at |
Igkv6-15 |
immunoglobulin kappa variable 6-15 |
6 |
|
U55641 |
108022 |
4 |
immunoglobulin production extracellular space immune response |
|
| 1451962_at |
Igkv6-20 |
immunoglobulin kappa variable 6-20 |
6 |
|
L41881 |
108024 |
6 |
immunoglobulin production extracellular space immune response |
|
| 1419645_at |
Cstf2 |
cleavage stimulation factor, 3' pre-RNA subunit 2 |
X |
134059175, 134059175 |
BM120662 |
108062 |
40 |
nucleic acid binding RNA binding mRNA binding nucleus nucleoplasm mRNA cleavage and polyadenylation specificity factor complex mRNA cleavage and polyadenylation specificity factor complex mRNA processing nuclear body mRNA 3'-end processing cleavage body |
03015 |
| 1420994_at |
B3gnt5 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 |
16 |
19760233 |
BM214359 |
108105 |
23 |
Golgi membrane Golgi apparatus protein glycosylation protein O-linked glycosylation lipid metabolic process multicellular organism development central nervous system development beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity membrane transferase activity glycosyltransferase activity hexosyltransferase activity sphingolipid biosynthetic process lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity |
00601 01100 |
| 1437506_at |
Adamts6 |
ADAM metallopeptidase with thrombospondin type 1 motif 6 |
13 |
104287834 |
AV286717 |
108154 |
19 |
kidney development cardiac septum development metalloendopeptidase activity proteolysis heart development extracellular matrix organization extracellular matrix aorta development coronary vasculature development |
|
| 1436780_at |
Ogt |
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) |
X |
101640217, 101640050 |
BG065325 |
108155 |
161 |
negative regulation of transcription by RNA polymerase II histone acetyltransferase complex mitophagy positive regulation of transcription from RNA polymerase II promoter by glucose euchromatin negative regulation of protein phosphorylation positive regulation of protein phosphorylation catalytic activity protein binding phosphatidylinositol-3,4,5-trisphosphate binding intracellular anatomical structure nucleus nucleus nucleus nucleus nucleoplasm cytoplasm mitochondrion cytosol plasma membrane glucosamine metabolic process regulation of glycolytic process regulation of gluconeogenesis chromatin organization regulation of transcription by RNA polymerase II protein O-linked glycosylation protein O-linked glycosylation protein O-linked glycosylation protein O-linked glycosylation protein O-linked glycosylation apoptotic process N-acetyltransferase activity lipid binding positive regulation of gene expression negative regulation of peptidyl-threonine phosphorylation membrane protein N-acetylglucosaminyltransferase activity protein processing transferase activity glycosyltransferase activity protein N-acetylglucosaminyltransferase complex protein domain specific binding hemopoiesis negative regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of protein ubiquitination negative regulation of protein ubiquitination chromatin DNA binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process response to insulin circadian regulation of gene expression protein-containing complex negative regulation of peptidyl-serine phosphorylation regulation of Rac protein signal transduction peptide binding zymogen granule identical protein binding cell projection neuronal cell body NSL complex protein-containing complex binding synapse synapse positive regulation of translation positive regulation of cell size positive regulation of proteolysis positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of insulin receptor signaling pathway positive regulation of lipid biosynthetic process intracellular distribution of mitochondria rhythmic process regulation of synapse assembly regulation of synapse assembly regulation of synapse assembly cellular response to lipopolysaccharide cellular response to glucose stimulus negative regulation of protein targeting to membrane protein O-acetylglucosaminyltransferase activity protein O-acetylglucosaminyltransferase activity protein O-acetylglucosaminyltransferase activity protein O-acetylglucosaminyltransferase activity regulation of neurotransmitter receptor localization to postsynaptic specialization membrane regulation of neurotransmitter receptor localization to postsynaptic specialization membrane regulation of neurotransmitter receptor localization to postsynaptic specialization membrane glutamatergic synapse glutamatergic synapse glutamatergic synapse glutamatergic synapse GABA-ergic synapse presynaptic cytosol postsynaptic cytosol positive regulation of cold-induced thermogenesis cerebellar granule cell to Purkinje cell synapse negative regulation of cellular response to hypoxia positive regulation of protein localization to nucleus negative regulation of stem cell population maintenance positive regulation of stem cell population maintenance positive regulation of reactive oxygen species biosynthetic process positive regulation of TORC1 signaling |
00514 |
| 1435222_at |
Foxp1 |
forkhead box P1 |
6 |
-98925341, -98925341, -98925341, -98925341 |
BM220880 |
108655 |
301 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific core promoter sequence-specific DNA binding transcription coregulator binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific positive regulation of mesenchymal cell proliferation pre-B cell differentiation positive regulation of immunoglobulin production negative regulation of B cell apoptotic process DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleus regulation of DNA-templated transcription regulation of transcription by RNA polymerase II transcription by RNA polymerase II DNA damage response heart development skeletal muscle tissue development motor neuron axon guidance embryo development embryo development regulation of gene expression positive regulation of endothelial cell migration negative regulation of gene expression ventral spinal cord development osteoclast differentiation lung development response to lipopolysaccharide regulation of interleukin-1 beta production regulation of interleukin-12 production regulation of tumor necrosis factor production positive regulation of interleukin-21 production immunoglobulin V(D)J recombination osteoclast development macrophage activation monocyte activation endothelial cell activation identical protein binding identical protein binding sequence-specific DNA binding protein self-association regulation of monocyte differentiation negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II metal ion binding positive regulation of smooth muscle cell proliferation smooth muscle tissue development positive regulation of epithelial cell proliferation nuclear androgen receptor binding regulation of inflammatory response positive regulation of B cell receptor signaling pathway cardiac muscle cell differentiation regulation of cardiac muscle cell proliferation regulation of cardiac muscle cell proliferation negative regulation of androgen receptor signaling pathway negative regulation of cell growth involved in cardiac muscle cell development lung secretory cell differentiation T follicular helper cell differentiation innate vocalization behavior regulation of action potential regulation of defense response to bacterium regulation of lung goblet cell differentiation negative regulation of lung goblet cell differentiation regulation of macrophage colony-stimulating factor production positive regulation of hydrogen peroxide-mediated programmed cell death regulation of endothelial tube morphogenesis cellular response to ionomycin sequence-specific double-stranded DNA binding regulation of chemokine (C-X-C motif) ligand 2 production |
|
| 1426473_at |
Dnajc9 |
DnaJ heat shock protein family (Hsp40) member C9 |
14 |
-20384637 |
BM942465 |
108671 |
26 |
extracellular space nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol plasma membrane nucleosome assembly membrane heat shock protein binding heat shock protein binding positive regulation of ATP-dependent activity histone binding protein-folding chaperone binding protein folding chaperone complex |
|
| 1435996_at |
Card11 |
caspase recruitment domain family, member 11 |
5 |
-140872998 |
AV095659 |
108723 |
92 |
immunological synapse immune system process immunoglobulin production protein binding cytoplasm cytoplasm plasma membrane plasma membrane plasma membrane signal transduction canonical NF-kappaB signal transduction membrane B cell differentiation positive regulation of B cell proliferation T cell costimulation CBM complex interleukin-2 production positive regulation of interleukin-2 production positive regulation of interleukin-2 production CD4-positive, alpha-beta T cell proliferation TORC1 signaling B cell proliferation T cell activation regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction protein self-association thymic T cell selection membrane raft regulation of B cell differentiation regulation of T cell differentiation lymphocyte activation homeostasis of number of cells CARD domain binding CARD domain binding regulation of immune response positive regulation of T cell receptor signaling pathway positive regulation of T cell receptor signaling pathway positive regulation of T cell activation positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity protein homooligomerization positive regulation of CD4-positive, alpha-beta T cell proliferation |
04660 04662 |
| 1437152_at |
Mex3b |
mex3 RNA binding family member B |
7 |
82867332 |
BG072837 |
108797 |
22 |
P-body nucleic acid binding RNA binding nucleus nucleoplasm cytoplasm cytosol phagocytosis positive regulation of cell-cell adhesion GTPase activating protein binding positive regulation of GTPase activity metal ion binding positive regulation of phagocytosis establishment of localization in cell protein localization to cell cortex cell-cell adhesion |
|
| 1456541_x_at |
Atad3a |
ATPase family, AAA domain containing 3A |
4 |
-155740639 |
BB357220 |
108888 |
53 |
nucleotide binding protein binding ATP binding mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrion organization membrane ATP hydrolysis activity mitochondrial nucleoid identical protein binding |
|
| 1426897_at |
Rcc2 |
regulator of chromosome condensation 2 |
4 |
140701472 |
AV122997 |
108911 |
37 |
chromosome, centromeric region guanyl-nucleotide exchange factor activity nucleus chromosome cytoplasm cytoskeleton microtubule plasma membrane cell cycle integrin-mediated signaling pathway microtubule binding regulation of fibroblast migration positive regulation of G2/M transition of mitotic cell cycle membrane membrane protein kinase binding protein domain specific binding regulation of cell migration midbody small GTPase binding small GTPase binding small GTPase binding early endosome membrane negative regulation of GTPase activity negative regulation of GTPase activity negative regulation of GTPase activity chromosome, centromeric core domain establishment of protein localization focal adhesion assembly cell division negative regulation of focal adhesion assembly positive regulation of attachment of spindle microtubules to kinetochore chromosome passenger complex localization to kinetochore activation of GTPase activity negative regulation of substrate adhesion-dependent cell spreading regulation of ruffle assembly regulation of ruffle assembly mitotic spindle midzone |
|
| 1433776_at |
Lhfpl6 |
LHFPL tetraspan subfamily member 6 |
3 |
53041546 |
AV149705 |
108927 |
16 |
molecular_function biological_process membrane membrane |
|
| 1438487_s_at |
Zzz3 |
zinc finger, ZZ domain containing 3 |
3 |
152396683, 152396002, 152395472 |
BB724567 |
108946 |
28 |
DNA binding nucleus nucleoplasm nucleolus chromatin organization regulation of DNA-templated transcription regulation of transcription by RNA polymerase II zinc ion binding methylated histone binding regulation of embryonic development metal ion binding regulation of cell division regulation of cell division regulation of cell cycle regulation of cell cycle lysine-acetylated histone binding mitotic spindle regulation of tubulin deacetylation histone reader activity ATAC complex ATAC complex |
|
| 1454850_at |
Tbc1d10c |
TBC1 domain family, member 10c |
19 |
-4184356 |
AV060417 |
108995 |
21 |
GTPase activator activity GTPase activator activity plasma membrane filopodium membrane calcineurin-NFAT signaling cascade B cell activation retrograde transport, endosome to Golgi negative regulation of B cell activation negative regulation of B cell activation ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade negative regulation of calcineurin-NFAT signaling cascade activation of GTPase activity |
|
| 1440202_at |
5930412I24Rik |
RIKEN cDNA 5930412I24 gene |
13 |
|
BB036159 |
109206 |
1 |
molecular_function cellular_component biological_process |
|
| 1427957_at |
Adtrp |
androgen dependent TFPI regulating protein |
13 |
-41763147, -41763147 |
AI256077 |
109254 |
16 |
positive regulation of protein phosphorylation cell migration involved in sprouting angiogenesis negative regulation of leukocyte migration negative regulation of extracellular matrix constituent secretion plasma membrane caveola lipid metabolic process cell surface positive regulation of gene expression endomembrane system membrane hydrolase activity negative regulation of blood coagulation long-chain fatty acid catabolic process negative regulation of protein secretion cellular response to oxidised low-density lipoprotein particle stimulus negative regulation of leukocyte cell-cell adhesion negative regulation of lymphocyte migration |
|
| 1424108_at |
Glo1 |
glyoxalase 1 |
17 |
-30592861 |
BC024663 |
109801 |
110 |
lactoylglutathione lyase activity lactoylglutathione lyase activity nucleoplasm cytosol plasma membrane regulation of transcription by RNA polymerase II glutathione metabolic process zinc ion binding zinc ion binding methylglyoxal metabolic process lyase activity methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione osteoclast differentiation negative regulation of apoptotic process metal ion binding |
00620 |
| 1417741_at |
Pygl |
liver glycogen phosphorylase |
12 |
-70190814 |
NM_133198 |
110095 |
42 |
nucleotide binding purine nucleobase binding catalytic activity 1,4-alpha-oligoglucan phosphorylase activity protein binding ATP binding glucose binding cytoplasm cytoplasm carbohydrate metabolic process glycogen metabolic process glycogen catabolic process glycogen catabolic process glycogen catabolic process 5-phosphoribose 1-diphosphate biosynthetic process metabolic process glycogen phosphorylase activity glycogen phosphorylase activity glycogen phosphorylase activity response to bacterium AMP binding transferase activity glycosyltransferase activity vitamin binding pyridoxal phosphate binding pyridoxal phosphate binding carbohydrate binding bile acid binding glucose homeostasis identical protein binding necroptotic process linear malto-oligosaccharide phosphorylase activity SHG alpha-glucan phosphorylase activity |
00500 04910 |
| 1439141_at |
Gpr18 |
G protein-coupled receptor 18 |
14 |
-121911433 |
BG145550 |
110168 |
27 |
CD8-positive, alpha-beta intraepithelial T cell differentiation CD8-positive, alpha-beta intraepithelial T cell differentiation CD8-positive, gamma-delta intraepithelial T cell differentiation CD8-positive, gamma-delta intraepithelial T cell differentiation negative regulation of leukocyte chemotaxis G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane cytoplasmic vesicle negative regulation of tumor necrosis factor production positive regulation of Rho protein signal transduction |
|
| 1437380_x_at |
Pgd |
phosphogluconate dehydrogenase |
4 |
-149149990, -149149990 |
BB558114 |
110208 |
56 |
phosphogluconate dehydrogenase (decarboxylating) activity phosphogluconate dehydrogenase (decarboxylating) activity phosphogluconate dehydrogenase (decarboxylating) activity cytoplasm cytosol cytosol pentose-phosphate shunt NADP metabolic process phosphogluconate 2-dehydrogenase activity pentose-phosphate shunt, oxidative branch pentose-phosphate shunt, oxidative branch pentose-phosphate shunt, oxidative branch oxidoreductase activity pentose biosynthetic process D-gluconate metabolic process carbohydrate binding carboxylic acid binding D-gluconate catabolic process NADP binding NADP binding |
00030 00480 01100 |
| 1448856_a_at |
Msra |
methionine sulfoxide reductase A |
14 |
-64122620, -64122620, -64122620, -64122620, -64122620 |
NM_026322 |
110265 |
84 |
nucleus nucleoplasm cytoplasm mitochondrion cytosol plasma membrane peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity actin cytoskeleton membrane oxidoreductase activity midbody cellular response to oxidative stress L-methionine-(S)-S-oxide reductase activity intracellular membrane-bounded organelle |
|
| 1437993_x_at |
Qdpr |
quinoid dihydropteridine reductase |
5 |
-45434031 |
BB221333 |
110391 |
48 |
6,7-dihydropteridine reductase activity 6,7-dihydropteridine reductase activity cytoplasm cytoplasm mitochondrion L-phenylalanine catabolic process tetrahydrobiopterin biosynthetic process tetrahydrobiopterin biosynthetic process oxidoreductase activity identical protein binding NADPH binding NADPH binding NADH binding NADH binding |
00790 01100 |
| 1417185_at |
Ly6a |
lymphocyte antigen 6 family member A |
15 |
-74994876 |
BC002070 |
110454 |
192 |
protein binding intracellular anatomical structure plasma membrane plasma membrane response to bacterium external side of plasma membrane membrane acetylcholine receptor inhibitor activity acetylcholine receptor binding acetylcholine receptor signaling pathway side of membrane |
|
| 1454843_at |
Prps2 |
phosphoribosyl pyrophosphate synthetase 2 |
X |
-167346319 |
BM934034 |
110639 |
26 |
nucleotide binding magnesium ion binding ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding ATP binding cytoplasm cytosol 5-phosphoribose 1-diphosphate biosynthetic process 5-phosphoribose 1-diphosphate biosynthetic process 5-phosphoribose 1-diphosphate biosynthetic process 5-phosphoribose 1-diphosphate biosynthetic process pentose-phosphate shunt purine nucleotide biosynthetic process AMP biosynthetic process ribonucleoside monophosphate biosynthetic process nucleotide biosynthetic process AMP binding kinase activity phosphorylation transferase activity GDP binding carbohydrate binding protein-containing complex identical protein binding ADP binding cellular biosynthetic process metal ion binding |
00030 00230 01100 |
| 1428719_at |
Iglc2 |
immunoglobulin lambda constant 2 |
16 |
|
AK008551 |
110786 |
29 |
antigen binding extracellular region plasma membrane immunoglobulin mediated immune response IgG immunoglobulin complex IgG immunoglobulin complex |
|
| 1427233_at |
Tshz1 |
teashirt zinc finger family member 1 |
18 |
-84011626, -84011626 |
AV291373 |
110796 |
52 |
DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding DNA binding protein binding nucleus nucleus regulation of transcription by RNA polymerase II multicellular organism development anterior/posterior pattern specification regulation of gene expression middle ear morphogenesis metal ion binding soft palate development |
|
| 1452430_s_at |
Srsf1 |
serine and arginine-rich splicing factor 1 |
11 |
88047372 |
X66091 |
110809 |
110 |
alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome mRNA 5'-splice site recognition in utero embryonic development nucleic acid binding RNA binding mRNA binding mRNA binding mRNA binding protein binding nucleus nucleus nucleus nucleoplasm spliceosomal complex cytoplasm mRNA processing RNA splicing RNA splicing nuclear speck nuclear speck nuclear speck signal transduction involved in regulation of gene expression signal transduction involved in regulation of gene expression positive regulation of RNA splicing protein localization to nucleus exon-exon junction complex protein kinase B binding regulation of RNA splicing DNA topoisomerase binding mRNA stabilization mRNA stabilization RS domain binding mRNA transport cardiac muscle contraction catalytic step 2 spliceosome cellular response to interleukin-17 interleukin-17-mediated signaling pathway interleukin-17-mediated signaling pathway molecular function regulator activity protein localization to P-body |
03040 |
| 1418231_at |
Lims1 |
LIM and senescent cell antigen-like domains 1 |
10 |
58323546, 58351962, 58394372, 58371453 |
BC005621 |
110829 |
73 |
protein binding cytoplasm plasma membrane cell-cell junction cell-cell junction focal adhesion focal adhesion focal adhesion cell-matrix adhesion establishment or maintenance of cell polarity integrin-mediated signaling pathway zinc ion binding positive regulation of gene expression positive regulation of cell-substrate adhesion membrane protein kinase binding protein-containing complex tumor necrosis factor-mediated signaling pathway chordate embryonic development positive regulation of canonical NF-kappaB signal transduction positive regulation of GTPase activity protein-containing complex binding establishment of protein localization cell-cell junction organization cell-cell junction organization negative regulation of DNA-templated transcription metal ion binding perinuclear region of cytoplasm positive regulation of focal adhesion assembly neural precursor cell proliferation anchoring junction hepatocyte apoptotic process cell-cell adhesion cell-cell adhesion positive regulation of substrate adhesion-dependent cell spreading positive regulation of substrate adhesion-dependent cell spreading negative regulation of hepatocyte apoptotic process negative regulation of cholangiocyte proliferation cholangiocyte proliferation negative regulation of neural precursor cell proliferation negative regulation of hepatocyte proliferation positive regulation of integrin-mediated signaling pathway positive regulation of integrin-mediated signaling pathway |
|
| 1448138_at |
Ptpa |
protein phosphatase 2 protein activator |
2 |
30441852, 30416049 |
NM_138748 |
110854 |
33 |
protein phosphatase type 2A complex protein phosphatase type 2A complex nucleotide binding peptidyl-prolyl cis-trans isomerase activity peptidyl-prolyl cis-trans isomerase activity phosphoprotein phosphatase activity signaling receptor binding ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm mitotic spindle organization protein tyrosine phosphatase activator activity protein tyrosine phosphatase activator activity isomerase activity phosphatase activator activity protein phosphatase regulator activity negative regulation of phosphoprotein phosphatase activity positive regulation of phosphoprotein phosphatase activity calcium channel complex positive regulation of protein dephosphorylation negative regulation of protein dephosphorylation protein homodimerization activity positive regulation of apoptotic process regulation of phosphoprotein phosphatase activity protein phosphatase 2A binding ATPase complex |
|
| 1421840_at |
Abca1 |
ATP-binding cassette, sub-family A member 1 |
4 |
-53030788 |
BB144704 |
11303 |
455 |
nucleotide binding peptide secretion signaling receptor binding protein binding ATP binding phospholipid transporter activity phospholipid transporter activity phospholipid transporter activity endosome Golgi apparatus plasma membrane plasma membrane protein lipidation phagocytosis, engulfment lysosome organization G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway high-density lipoprotein particle binding cholesterol metabolic process cholesterol metabolic process protein transmembrane transporter activity protein secretion protein secretion external side of plasma membrane cell surface positive regulation of cholesterol efflux phospholipid transport membrane endosomal transport basolateral plasma membrane ATP hydrolysis activity syntaxin binding signal release signal release endocytic vesicle cholesterol transport phosphatidylcholine binding small GTPase binding intracellular cholesterol transport regulation of Cdc42 protein signal transduction cholesterol efflux cholesterol efflux cholesterol efflux phospholipid efflux phospholipid efflux phospholipid efflux phospholipid efflux apolipoprotein binding apolipoprotein A-I binding apolipoprotein A-I receptor activity high-density lipoprotein particle assembly response to laminar fluid shear stress lipoprotein metabolic process lipoprotein biosynthetic process lipoprotein biosynthetic process ATPase-coupled transmembrane transporter activity ATPase-coupled transmembrane transporter activity cholesterol homeostasis intracellular membrane-bounded organelle intracellular membrane-bounded organelle reverse cholesterol transport reverse cholesterol transport membrane raft phospholipid translocation phospholipid translocation phagocytic vesicle sphingolipid floppase activity perinuclear region of cytoplasm ATPase binding establishment of localization in cell transmembrane transport phospholipid homeostasis platelet dense granule organization cellular response to lipopolysaccharide cellular response to retinoic acid protein transmembrane transport positive regulation of high-density lipoprotein particle assembly phosphatidylcholine floppase activity phosphatidylcholine floppase activity phosphatidylserine floppase activity phosphatidylserine floppase activity intracellular vesicle cholesterol transfer activity cholesterol transfer activity cholesterol transfer activity export across plasma membrane ATPase-coupled intramembrane lipid transporter activity floppase activity ABC-type transporter activity |
02010 04975 |
| 1428847_a_at |
Macf1 |
microtubule-actin crosslinking factor 1 |
4 |
-123349632 |
BM248206 |
11426 |
95 |
mesoderm formation actin binding actin binding structural molecule activity calcium ion binding protein binding cytoplasm cytoplasm cytoplasm Golgi apparatus cytoskeleton microtubule microtubule microtubule intermediate filament plasma membrane cell cortex post-translational protein targeting to endoplasmic reticulum membrane establishment or maintenance of cell polarity microtubule binding protein localization regulation of epithelial cell migration postsynaptic density actin cytoskeleton actin cytoskeleton microtubule cytoskeleton membrane membrane Wnt signaling pathway Wnt signaling pathway cell migration ATP hydrolysis activity positive regulation of Wnt signaling pathway positive regulation of Wnt signaling pathway regulation of cell migration ruffle membrane regulation of microtubule-based process regulation of microtubule-based process regulation of microtubule-based process wound healing wound healing cell projection Golgi to plasma membrane protein transport intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization positive regulation of axon extension metal ion binding microtubule minus-end binding actin filament binding regulation of focal adhesion assembly regulation of focal adhesion assembly regulation of focal adhesion assembly regulation of neuron projection arborization |
|
| 1424654_at |
Acp2 |
acid phosphatase 2, lysosomal |
2 |
91202911 |
BB022890 |
11432 |
43 |
skeletal system development phosphotyrosine residue binding acid phosphatase activity acid phosphatase activity acid phosphatase activity acid phosphatase activity phosphoprotein phosphatase activity lysosome lysosome lysosome lysosome lysosome organization lysosome organization response to organic substance membrane dephosphorylation hydrolase activity autophagic cell death |
00740 04142 |
| 1431609_a_at |
Acp5 |
acid phosphatase 5, tartrate resistant |
9 |
-22126726, -22126726, -22126726 |
AK008391 |
11433 |
113 |
acid phosphatase activity acid phosphatase activity acid phosphatase activity acid phosphatase activity extracellular space lysosome lysosome nitric oxide biosynthetic process negative regulation of cell adhesion ferrous iron binding ferrous iron binding ferric iron binding ferric iron binding macrophage cytokine production negative regulation of macrophage cytokine production dephosphorylation hydrolase activity positive regulation of cell migration response to lipopolysaccharide interleukin-1 beta production interleukin-12 production tumor necrosis factor production negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production negative regulation of tumor necrosis factor production negative regulation of superoxide anion generation response to cytokine superoxide anion generation negative regulation of nitric oxide biosynthetic process bone resorption bone resorption metal ion binding negative regulation of inflammatory response defense response to Gram-positive bacterium bone morphogenesis |
00740 04142 04380 05323 |
| 1429379_at |
Lyve1 |
lymphatic vessel endothelial hyaluronan receptor 1 |
7 |
-110850606 |
AV124537 |
114332 |
389 |
positive regulation of cellular extravasation transmembrane signaling receptor activity transmembrane signaling receptor activity hyaluronic acid binding hyaluronic acid binding hyaluronic acid binding plasma membrane plasma membrane plasma membrane glycosaminoglycan catabolic process receptor-mediated endocytosis receptor-mediated endocytosis cell adhesion membrane hyaluronan catabolic process cargo receptor activity cargo receptor activity cell periphery |
|
| 1416871_at |
Adam8 |
a disintegrin and metallopeptidase domain 8 |
7 |
-139978931 |
NM_007403 |
11501 |
76 |
cell morphogenesis angiogenesis podosome podosome leukocyte migration involved in inflammatory response positive regulation of acute inflammatory response positive regulation of cellular extravasation positive regulation of cellular extravasation metalloendopeptidase activity metalloendopeptidase activity integrin binding calcium ion binding protein binding cytoplasm plasma membrane plasma membrane proteolysis proteolysis inflammatory response inflammatory response cell-matrix adhesion canonical NF-kappaB signal transduction peptidase activity metallopeptidase activity metallopeptidase activity zinc ion binding cell surface positive regulation of epithelial to mesenchymal transition membrane hydrolase activity regulation of cell-cell adhesion regulation of cell-cell adhesion phagolysosome dense core granule membrane positive regulation of T cell differentiation in thymus specific granule positive regulation of MAPK cascade negative regulation of neuron apoptotic process blood vessel endothelial cell migration positive regulation of innate immune response regulation of osteoclast differentiation positive regulation of bone resorption positive regulation of bone resorption positive regulation of cell adhesion metal ion binding lymphocyte chemotaxis tissue morphogenesis positive regulation of inflammatory response cell adhesion molecule binding cell adhesion molecule binding cell adhesion molecule binding positive regulation of membrane protein ectodomain proteolysis positive regulation of membrane protein ectodomain proteolysis positive regulation of membrane protein ectodomain proteolysis positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction membrane fusion positive regulation of thymocyte apoptotic process tertiary granule alpha9-beta1 integrin-ADAM8 complex cellular response to hypoxia osteoclast fusion cell-cell adhesion positive regulation of transforming growth factor beta1 activation positive regulation of tumor necrosis factor (ligand) superfamily member 11 production positive regulation of neutrophil extravasation negative regulation of thymocyte aggregation positive regulation of T cell migration positive regulation of fibronectin-dependent thymocyte migration positive regulation of eosinophil migration |
|
| 1450065_at |
Adcy7 |
adenylate cyclase 7 |
8 |
88282991, 88289065, 88272402, 88294203 |
NM_007406 |
11513 |
34 |
nucleotide binding regulation of adaptive immune response adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity ATP binding plasma membrane cAMP biosynthetic process cAMP biosynthetic process cAMP biosynthetic process adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway activation of adenylate cyclase activity adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway cyclic nucleotide biosynthetic process membrane lyase activity phosphorus-oxygen lyase activity intracellular signal transduction metal ion binding cellular response to lithium ion cellular response to ethanol negative regulation of cytokine production involved in inflammatory response |
00230 04020 04062 04114 04270 04540 04912 04914 04916 04970 04971 04972 04976 05414 |
| 1435287_at |
Add2 |
adducin 2 |
6 |
86028680, 86078047, 86028680, 86078047 |
AV298858 |
11519 |
67 |
actin binding structural constituent of cytoskeleton calmodulin binding cytoplasm cytoskeleton cytoskeleton plasma membrane plasma membrane monoatomic ion transport synapse assembly synapse assembly synapse assembly F-actin capping protein complex postsynaptic density postsynaptic density membrane protein kinase binding hemopoiesis spectrin binding cytoplasmic vesicle positive regulation of protein binding protein homodimerization activity plasma membrane raft protein heterodimerization activity protein dimerization activity leukocyte migration leukocyte tethering or rolling actin filament binding actin filament binding barbed-end actin filament capping barbed-end actin filament capping actin filament bundle assembly protein-containing complex assembly postsynapse glutamatergic synapse |
|
| 1448318_at |
Plin2 |
perilipin 2 |
4 |
-86656564 |
NM_007408 |
11520 |
154 |
protein binding nucleus cytoplasm lipid droplet lipid droplet lipid droplet lipid droplet cytosol cytosol cytosol plasma membrane positive regulation of sequestering of triglyceride long-chain fatty acid transport membrane lipid storage lipid storage lipid storage cellular response to glucose starvation lipid droplet disassembly |
|
| 1435368_a_at |
Parp1 |
poly (ADP-ribose) polymerase family, member 1 |
1 |
180568890 |
BB767586 |
11545 |
673 |
negative regulation of transcription by RNA polymerase II telomere maintenance chromatin chromatin immune system process DNA binding chromatin binding chromatin binding damaged DNA binding catalytic activity NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity protein binding nucleus nucleus nucleus nuclear envelope nucleoplasm nucleoplasm transcription regulator complex chromosome nucleolus nucleolus nucleolus cytoplasm mitochondrion cytosol DNA metabolic process DNA repair DNA repair DNA repair base-excision repair double-strand break repair double-strand break repair double-strand break repair apoptotic process DNA damage response mitochondrion organization mitochondrion organization transforming growth factor beta receptor signaling pathway metabolic process zinc ion binding positive regulation of cardiac muscle hypertrophy carbohydrate biosynthetic process protein autoprocessing nuclear body transferase activity glycosyltransferase activity nucleotidyltransferase activity enzyme binding protein kinase binding signal transduction involved in regulation of gene expression nuclear estrogen receptor binding DNA ADP-ribosylation nucleosome binding ubiquitin protein ligase binding mitochondrial DNA metabolic process negative regulation of interleukin-17 production positive regulation of DNA-templated transcription, elongation cellular response to insulin stimulus regulation of protein localization protein-containing complex protein-containing complex protein-DNA complex positive regulation of intracellular estrogen receptor signaling pathway negative regulation of transcription elongation by RNA polymerase II cellular response to oxidative stress cellular response to UV site of double-strand break protein modification process regulation of growth rate identical protein binding protein homodimerization activity histone deacetylase binding positive regulation of canonical NF-kappaB signal transduction mitochondrial DNA repair nuclear replication fork regulation of DNA methylation innate immune response regulation of circadian sleep/wake cycle, non-REM sleep negative regulation of innate immune response negative regulation of innate immune response negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II decidualization metal ion binding behavioral response to cocaine regulation of catalytic activity voluntary musculoskeletal movement NAD binding positive regulation of mitochondrial depolarization positive regulation of SMAD protein signal transduction positive regulation of necroptotic process RNA polymerase II-specific DNA-binding transcription factor binding protein poly-ADP-ribosylation protein poly-ADP-ribosylation protein poly-ADP-ribosylation protein auto-ADP-ribosylation R-SMAD binding protein localization to chromatin cellular response to superoxide replication fork reversal site of DNA damage site of DNA damage NAD DNA ADP-ribosyltransferase activity transcription regulator activator activity NAD+-protein-serine ADP-ribosyltransferase activity NAD+- protein-aspartate ADP-ribosyltransferase activity NAD+- protein-aspartate ADP-ribosyltransferase activity NAD+-protein-glutamate ADP-ribosyltransferase activity NAD+-protein-glutamate ADP-ribosyltransferase activity NAD+-protein-glutamate ADP-ribosyltransferase activity NAD+-protein-tyrosine ADP-ribosyltransferase activity NAD+-protein-histidine ADP-ribosyltransferase activity NAD+-histone H2BS6 serine ADP-ribosyltransferase activity NAD+-histone H3S10 serine ADP-ribosyltransferase activity NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity negative regulation of cGAS/STING signaling pathway positive regulation of protein localization to nucleus regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway regulation of single strand break repair positive regulation of single strand break repair positive regulation of single strand break repair negative regulation of adipose tissue development negative regulation of telomere maintenance via telomere lengthening cellular response to amyloid-beta positive regulation of myofibroblast differentiation regulation of base-excision repair positive regulation of double-strand break repair via homologous recombination cellular response to nerve growth factor stimulus NAD+-protein ADP-ribosyltransferase activity NAD+-protein ADP-ribosyltransferase activity NAD+-protein ADP-ribosyltransferase activity ATP generation from poly-ADP-D-ribose negative regulation of ATP biosynthetic process |
03410 |
| 1449383_at |
Adss1 |
adenylosuccinate synthase 1 |
12 |
112620046 |
NM_007421 |
11565 |
32 |
nucleotide binding GTPase activity adenylosuccinate synthase activity adenylosuccinate synthase activity adenylosuccinate synthase activity protein binding GTP binding cytoplasm cytoplasm cytoplasm purine nucleotide metabolic process purine nucleotide biosynthetic process AMP biosynthetic process aspartate metabolic process membrane ligase activity identical protein binding 'de novo' AMP biosynthetic process AMP salvage AMP salvage IMP metabolic process IMP metabolic process metal ion binding actin filament binding |
00230 00250 01100 |
| 1449838_at |
Crisp3 |
cysteine-rich secretory protein 3 |
17 |
-40221776 |
NM_009639 |
11572 |
18 |
extracellular region extracellular space cytoplasmic vesicle |
|
| 1418204_s_at |
Aif1 |
allograft inflammatory factor 1 |
17 |
-35170985 |
NM_019467 |
11629 |
273 |
ruffle microglial cell activation phagocytic cup positive regulation of protein phosphorylation actin binding calcium ion binding calcium ion binding protein binding nucleus nucleus cytoplasm cytoplasm cytosol cytoskeleton actin filament actin filament plasma membrane phagocytosis, engulfment positive regulation of cell population proliferation negative regulation of gene expression positive regulation of muscle hyperplasia membrane Rac protein signal transduction lamellipodium lamellipodium actin filament polymerization parallel actin filament bundle assembly positive regulation of cell migration ruffle membrane ruffle membrane ruffle membrane positive regulation of chemokine production positive regulation of interleukin-6 production cellular response to oxidative stress positive regulation of T cell proliferation cell projection negative regulation of apoptotic process perikaryon positive regulation of nitric oxide biosynthetic process metal ion binding perinuclear region of cytoplasm positive regulation of smooth muscle cell proliferation negative regulation of smooth muscle cell proliferation positive regulation of chemotaxis actin filament binding actin filament binding actin filament binding actin filament bundle assembly actin filament bundle assembly actin filament bundle assembly actin crosslink formation negative regulation of smooth muscle cell chemotaxis positive regulation of smooth muscle cell chemotaxis positive regulation of mononuclear cell migration positive regulation of monocyte chemotaxis positive regulation of fibroblast growth factor production ruffle assembly ruffle assembly ruffle assembly glial cell projection positive regulation of G1/S transition of mitotic cell cycle positive regulation of T cell migration |
|
| 1452016_at |
Alox5ap |
arachidonate 5-lipoxygenase activating protein |
5 |
149265003 |
BC026209 |
11690 |
44 |
leukotriene production involved in inflammatory response positive regulation of acute inflammatory response arachidonate 5-lipoxygenase activity glutathione transferase activity leukotriene-C4 synthase activity glutathione peroxidase activity protein binding nucleus nuclear envelope nuclear envelope endoplasmic reticulum endoplasmic reticulum leukotriene metabolic process enzyme activator activity membrane leukotriene biosynthetic process leukotriene biosynthetic process leukotriene biosynthetic process leukotriene biosynthetic process lipoxygenase pathway enzyme binding nuclear membrane identical protein binding protein-containing complex binding arachidonic acid binding protein homotrimerization cellular response to calcium ion |
|
| 1418685_at |
Tirap |
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein |
9 |
-35184390, -35184390, -35184390 |
NM_054096 |
117149 |
130 |
immune system process protein kinase C binding protein binding phosphatidylinositol-4,5-bisphosphate binding cytoplasm cytoplasm plasma membrane plasma membrane inflammatory response signal transduction cell surface receptor signaling pathway cell surface receptor signaling pathway response to bacterium cell surface macrophage cytokine production membrane myeloid cell differentiation endocytic vesicle positive regulation of B cell proliferation extrinsic component of cytoplasmic side of plasma membrane positive regulation of protein-containing complex assembly response to lipopolysaccharide ruffle membrane tumor necrosis factor production regulation of interferon-beta production regulation of interleukin-15 production positive regulation of interleukin-12 production positive regulation of interleukin-15 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production regulation of stress-activated MAPK cascade positive regulation of toll-like receptor 2 signaling pathway positive regulation of toll-like receptor 3 signaling pathway toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway positive regulation of toll-like receptor 4 signaling pathway signaling adaptor activity signaling adaptor activity Toll-like receptor 4 binding Toll-like receptor 4 binding Toll-like receptor 2 binding Toll-like receptor 2 binding Toll-like receptor 2 binding TIRAP-dependent toll-like receptor 4 signaling pathway identical protein binding identical protein binding positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of JUN kinase activity innate immune response regulation of innate immune response positive regulation of innate immune response positive regulation of JNK cascade defense response to Gram-positive bacterium positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity molecular adaptor activity positive regulation of macrophage cytokine production positive regulation of ERK1 and ERK2 cascade 3'-UTR-mediated mRNA stabilization cellular response to bacterial lipopeptide cellular response to lipoteichoic acid positive regulation of neutrophil chemotaxis positive regulation of chemokine (C-X-C motif) ligand 1 production positive regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of chemokine (C-X-C motif) ligand 2 production |
04620 |
| 1460197_a_at |
Steap4 |
STEAP family member 4 |
5 |
7960471 |
NM_054098 |
117167 |
39 |
nucleoplasm endosome endosome Golgi apparatus plasma membrane plasma membrane plasma membrane plasma membrane monoatomic ion transport iron ion transport cupric reductase activity cupric reductase activity electron transfer activity copper ion import copper ion import membrane oxidoreductase activity heme binding iron import into cell fat cell differentiation metal ion binding ferric-chelate reductase (NADPH) activity ferric-chelate reductase (NADPH) activity ferric-chelate reductase (NADPH) activity protein homotrimerization FAD binding iron ion import across cell outer membrane |
|
| 1422573_at |
Ampd3 |
adenosine monophosphate deaminase 3 |
7 |
110772603, 110768205, 110773635, 110768621 |
D85596 |
11717 |
39 |
AMP deaminase activity AMP deaminase activity AMP deaminase activity AMP deaminase activity cytosol IMP biosynthetic process IMP biosynthetic process IMP biosynthetic process AMP catabolic process nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process hydrolase activity deaminase activity IMP salvage erythrocyte homeostasis ADP metabolic process ADP catabolic process AMP metabolic process AMP metabolic process ATP metabolic process ATP metabolic process GTP metabolic process GTP metabolic process metal ion binding energy homeostasis |
00230 01100 |
| 1425718_a_at |
Ivns1abp |
influenza virus NS1A binding protein |
1 |
151344485, 151344497, 151344497 |
BC004092 |
117198 |
29 |
protein binding nucleus cytoplasm cytosol cytoskeleton RNA splicing response to virus negative regulation of protein ubiquitination intrinsic apoptotic signaling pathway negative regulation of intrinsic apoptotic signaling pathway |
|
| 1450627_at |
Ank |
progressive ankylosis |
15 |
27466676 |
NM_020332 |
11732 |
84 |
inorganic phosphate transmembrane transporter activity inorganic phosphate transmembrane transporter activity ATP transmembrane transporter activity extracellular region plasma membrane plasma membrane gene expression gene expression phosphate ion transmembrane transporter activity membrane membrane bone mineralization bone mineralization regulation of bone mineralization inorganic diphosphate transmembrane transporter activity inorganic diphosphate transmembrane transporter activity inorganic diphosphate transmembrane transporter activity inorganic diphosphate transport phosphate ion transmembrane transport muscle cell cellular homeostasis phosphate ion homeostasis calcium ion homeostasis diphosphate metabolic process diphosphate metabolic process cementum mineralization cementum mineralization inhibition of non-skeletal tissue mineralization inhibition of non-skeletal tissue mineralization response to sodium phosphate ATP export |
|
| 1418468_at |
Anxa11 |
annexin A11 |
14 |
25842154 |
NM_013469 |
11744 |
34 |
phosphatidylserine binding calcium ion binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding nucleus nuclear envelope nucleoplasm cytoplasm cytoplasm cytoplasm spindle cytosol cytoskeleton plasma membrane phagocytosis cell cycle phosphatidylethanolamine binding midbody cytokinetic process cytokinetic process specific granule azurophil granule S100 protein binding phagocytic vesicle calcium-dependent protein binding cell division response to calcium ion collagen-containing extracellular matrix |
|
| 1460330_at |
Anxa3 |
annexin A3 |
5 |
96793384 |
AW702161 |
11745 |
33 |
phosphatidylserine binding phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding cytoplasm cytoplasm plasma membrane plasma membrane phagocytosis positive regulation of endothelial cell migration membrane phospholipase A2 inhibitor activity axon dendrite phagocytic vesicle membrane specific granule defense response to bacterium neuronal cell body neutrophil degranulation positive regulation of angiogenesis calcium-dependent protein binding positive regulation of DNA metabolic process positive regulation of DNA-binding transcription factor activity collagen-containing extracellular matrix |
|
| 1421223_a_at |
Anxa4 |
annexin A4 |
6 |
-86736839, -86736839 |
NM_013471 |
11746 |
42 |
phosphatidylserine binding kidney development calcium ion binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding nucleus cytoplasm cytoplasm plasma membrane plasma membrane regulation of transcription by RNA polymerase II Notch signaling pathway cell surface vesicle membrane membrane apical plasma membrane cytoplasmic vesicle nuclear membrane negative regulation of NF-kappaB transcription factor activity negative regulation of interleukin-8 production identical protein binding calcium-dependent protein binding perinuclear region of cytoplasm NF-kappaB binding collagen-containing extracellular matrix |
|
| 1452342_at |
Apbb2 |
amyloid beta precursor protein binding family B member 2 |
5 |
-66298724, -66298724 |
AW542721 |
11787 |
41 |
negative regulation of transcription by RNA polymerase II amyloid-beta binding amyloid-beta binding neuron migration protein binding nucleus nucleus cytoplasm cytoplasm endosome early endosome endoplasmic reticulum Golgi apparatus regulation of DNA-templated transcription smooth muscle contraction axon guidance transcription factor binding extracellular matrix organization maintenance of lens transparency positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of transcription by RNA polymerase II protein stabilization negative regulation of cell cycle phase transition |
|
| 1435543_at |
Apc |
APC, WNT signaling pathway regulator |
18 |
34247693, 34220983 |
BM124893 |
11789 |
1824 |
MAPK cascade MAPK cascade mitotic cytokinesis mitotic cytokinesis kinetochore cell fate specification kidney development endothelial cell proliferation endothelial cell proliferation negative regulation of endothelial cell proliferation negative regulation of endothelial cell proliferation hair follicle development protease binding protein binding nucleus nucleus cytoplasm cytoplasm Golgi apparatus centrosome cytoskeleton microtubule cytoplasmic microtubule plasma membrane adherens junction bicellular tight junction cell cortex apoptotic process DNA damage response microtubule depolymerization negative regulation of microtubule depolymerization negative regulation of microtubule depolymerization negative regulation of microtubule depolymerization metaphase/anaphase transition of mitotic cell cycle metaphase/anaphase transition of mitotic cell cycle mitotic spindle assembly checkpoint signaling cell adhesion establishment or maintenance of cell polarity pattern specification process pattern specification process nervous system development axonogenesis axonogenesis beta-catenin binding beta-catenin binding beta-catenin binding beta-catenin binding microtubule binding microtubule binding cell population proliferation cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation insulin receptor signaling pathway insulin receptor signaling pathway axis specification anterior/posterior pattern specification dorsal/ventral pattern formation proximal/distal pattern formation regulation of epithelial cell migration fibroblast migration positive regulation of fibroblast migration microtubule cytoskeleton membrane Wnt signaling pathway Wnt signaling pathway Wnt signaling pathway lateral plasma membrane catenin complex catenin complex cell migration cell migration cell migration stem cell population maintenance protein kinase regulator activity protein kinase binding protein kinase binding lamellipodium protein catabolic process negative regulation of Wnt signaling pathway negative regulation of Wnt signaling pathway regulation of cell migration positive regulation of cell migration axon dendrite growth cone growth cone synaptic vesicle membrane regulation of epithelial cell differentiation beta-catenin destruction complex beta-catenin destruction complex beta-catenin destruction complex positive regulation of microtubule polymerization cytoplasmic microtubule organization neuron projection development cell projection membrane positive regulation of pseudopodium assembly ubiquitin protein ligase binding nuclear membrane ruffle membrane regulation of microtubule-based process protein-containing complex T cell differentiation in thymus Scrib-APC-beta-catenin complex somatic stem cell population maintenance somatic stem cell population maintenance odontogenesis negative regulation of odontogenesis cell projection neuronal cell body positive regulation of apoptotic process negative regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process negative regulation of MAPK cascade negative regulation of MAPK cascade skin development axonal growth cone axonal growth cone neuron projection terminus canonical Wnt signaling pathway involved in negative regulation of apoptotic process canonical Wnt signaling pathway involved in positive regulation of apoptotic process fibroblast apoptotic process protein-containing complex binding gamma-catenin binding gamma-catenin binding regulation of cell differentiation regulation of cell differentiation positive regulation of cell differentiation regulation of osteoblast differentiation regulation of osteoclast differentiation positive regulation of protein catabolic process positive regulation of protein catabolic process positive regulation of protein catabolic process negative regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of cell adhesion muscle cell cellular homeostasis microtubule polymerization perinuclear region of cytoplasm thymus development epithelial cell proliferation epithelial cell proliferation negative regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation microtubule plus-end binding microtubule plus-end binding regulation of nitrogen compound metabolic process chromosome organization chromosome organization cell division regulation of cell cycle positive regulation of cell division regulation of attachment of spindle microtubules to kinetochore regulation of attachment of spindle microtubules to kinetochore retina development in camera-type eye negative regulation of cardiac muscle cell proliferation canonical Wnt signaling pathway epithelial cell proliferation involved in prostate gland development negative regulation of epithelial cell proliferation involved in prostate gland development protein-containing complex assembly anchoring junction dynein complex binding dynein complex binding cell body fiber negative regulation of canonical Wnt signaling pathway negative regulation of canonical Wnt signaling pathway negative regulation of canonical Wnt signaling pathway positive regulation of cold-induced thermogenesis negative regulation of cell cycle G1/S phase transition epithelial cell apoptotic process negative regulation of epithelial cell apoptotic process negative regulation of acinar cell proliferation negative regulation of acinar cell proliferation positive regulation of protein localization to centrosome positive regulation of protein localization to centrosome acinar cell proliferation acinar cell proliferation negative regulation of G1/S transition of mitotic cell cycle regulation of glutamate metabolic process positive regulation of fibroblast apoptotic process |
04310 04810 05200 05210 05213 05217 |
| 1449193_at |
Cd5l |
CD5 antigen-like |
3 |
87357880 |
NM_009690 |
11801 |
54 |
immune system process serine-type endopeptidase activity extracellular region cytoplasm plasma membrane plasma membrane apoptotic process inflammatory response cell surface cell surface membrane regulation of complement activation zymogen activation positive regulation of complement-dependent cytotoxicity |
|
| 1427442_a_at |
App |
amyloid beta precursor protein |
16 |
-84954435 |
BC005490 |
11820 |
1463 |
G2/M transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II mitotic cell cycle RNA polymerase II cis-regulatory region sequence-specific DNA binding G protein-coupled receptor binding microglial cell activation response to yeast positive regulation of protein phosphorylation suckling behavior astrocyte activation involved in immune response chromatin binding serine-type endopeptidase inhibitor activity signaling receptor binding signaling receptor binding frizzled binding insulin receptor binding integrin binding protein binding extracellular region extracellular space nucleus nuclear envelope lumen cytoplasm cytoplasm mitochondrion lysosome endosome early endosome early endosome early endosome endoplasmic reticulum Golgi apparatus Golgi apparatus Golgi apparatus Golgi-associated vesicle plasma membrane plasma membrane plasma membrane clathrin-coated pit cell-cell junction regulation of transcription by RNA polymerase II regulation of translation protein phosphorylation intracellular copper ion homeostasis intracellular copper ion homeostasis endocytosis apoptotic process response to oxidative stress cell adhesion regulation of epidermal growth factor-activated receptor activity G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway Notch signaling pathway axonogenesis axonogenesis central nervous system development learning or memory learning memory memory mating behavior locomotory behavior synaptic vesicle axo-dendritic transport axo-dendritic transport heparin binding cholesterol metabolic process cholesterol metabolic process negative regulation of cell population proliferation associative learning adult locomotory behavior visual learning cell surface cell surface cell surface negative regulation of peptidase activity regulation of gene expression regulation of gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of protein kinase A signaling positive regulation of peptidyl-threonine phosphorylation positive regulation of G2/M transition of mitotic cell cycle microglia development membrane membrane membrane axon midline choice point recognition neuron remodeling dendrite development dendrite development peptidase activator activity calcium-mediated signaling antibacterial humoral response antifungal humoral response enzyme binding COPII-coated ER to Golgi transport vesicle neuron differentiation neuron differentiation extracellular matrix organization peptidase inhibitor activity axon axon growth cone signaling receptor activator activity signaling receptor activator activity signaling receptor activator activity forebrain development forebrain development neuron projection development cytoplasmic vesicle neuromuscular junction positive regulation of protein binding positive regulation of chemokine production positive regulation of type II interferon production positive regulation of interleukin-1 beta production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of superoxide anion generation protein-containing complex acetylcholine receptor binding positive regulation of peptidyl-serine phosphorylation regulation of toll-like receptor signaling pathway apolipoprotein binding very-low-density lipoprotein particle low-density lipoprotein particle intermediate-density lipoprotein particle high-density lipoprotein particle ionotropic glutamate receptor signaling pathway ciliary rootlet regulation of multicellular organism growth chemoattractant activity identical protein binding protein homodimerization activity cell projection neuron projection neuron projection positive regulation of apoptotic process ion binding receptor complex positive regulation of cysteine-type endopeptidase activity involved in apoptotic process regulation of protein binding regulation of protein binding heparan sulfate proteoglycan binding positive regulation of MAPK cascade positive regulation of neuron apoptotic process positive regulation of cAMP-mediated signaling cell body main axon innate immune response membrane raft membrane raft apical part of cell positive regulation of nitric oxide biosynthetic process negative regulation of neuron differentiation negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of G protein-coupled receptor signaling pathway positive regulation of glycolytic process positive regulation of mitotic cell cycle positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of JNK cascade metal ion binding ephrin receptor binding transition metal ion binding protein heterodimerization activity receptor ligand activity astrocyte activation regulation of long-term neuronal synaptic plasticity perinuclear region of cytoplasm perinuclear region of cytoplasm collateral sprouting in absence of injury presynaptic active zone presynaptic active zone positive regulation of inflammatory response regulation of peptidyl-tyrosine phosphorylation low-density lipoprotein particle receptor binding RAGE receptor binding regulation of synapse structure or activity synapse organization defense response to Gram-negative bacterium defense response to Gram-positive bacterium positive regulation of calcium-mediated signaling neuromuscular process controlling balance cognition positive regulation of membrane protein ectodomain proteolysis protein-folding chaperone binding positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity synaptic assembly at neuromuscular junction spindle midzone positive regulation of protein metabolic process protein homooligomerization protein tetramerization neuron apoptotic process neuron apoptotic process PTB domain binding smooth endoplasmic reticulum calcium ion homeostasis recycling endosome long-term synaptic potentiation positive regulation of protein tyrosine kinase activity antimicrobial humoral immune response mediated by antimicrobial peptide neuron cellular homeostasis protein trimerization positive regulation of ERK1 and ERK2 cascade endosome to plasma membrane transport vesicle response to interleukin-1 growth factor receptor binding cellular response to norepinephrine stimulus positive regulation of monocyte chemotaxis negative regulation of canonical Wnt signaling pathway astrocyte projection presynapse postsynapse modulation of excitatory postsynaptic potential neuronal dense core vesicle amyloid-beta complex regulation of spontaneous synaptic transmission cytoplasmic polyadenylation positive regulation of receptor binding negative regulation of protein localization to nucleus regulation of amyloid-beta clearance negative regulation of long-term synaptic potentiation positive regulation of long-term synaptic potentiation positive regulation of non-canonical NF-kappaB signal transduction negative regulation of miRNA transcription regulation of dendritic spine maintenance positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process regulation of acetylcholine-gated cation channel activity regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway negative regulation of blood circulation negative regulation of blood circulation positive regulation of G protein-coupled receptor internalization positive regulation of endothelin production positive regulation of endothelin production positive regulation of protein import cellular response to amyloid-beta regulation of presynapse assembly positive regulation of response to endoplasmic reticulum stress regulation of amyloid fibril formation positive regulation of amyloid fibril formation regulation of response to calcium ion amyloid fibril formation neuron projection maintenance growth cone lamellipodium lipoprotein particle growth cone filopodium positive regulation of T cell migration positive regulation of excitatory postsynaptic potential positive regulation of extrinsic apoptotic signaling pathway |
05010 |
| 1419549_at |
Arg1 |
arginase, liver |
10 |
-24915206 |
NM_007482 |
11846 |
276 |
urea cycle positive regulation of endothelial cell proliferation adaptive immune response immune system process arginase activity arginase activity arginase activity extracellular space cytoplasm cytoplasm mitochondrial outer membrane cytosol arginine metabolic process hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines arginine catabolic process to ornithine arginine catabolic process to ornithine manganese ion binding manganese ion binding collagen biosynthetic process negative regulation of T cell proliferation identical protein binding defense response to protozoan neuronal cell body innate immune response negative regulation of activated T cell proliferation metal ion binding negative regulation of type II interferon-mediated signaling pathway positive regulation of neutrophil mediated killing of fungus regulation of L-arginine import across plasma membrane negative regulation of T-helper 2 cell cytokine production |
00330 01100 05146 |
| 1418847_at |
Arg2 |
arginase type II |
12 |
79130787 |
NM_009705 |
11847 |
119 |
urea cycle ureteric bud development adaptive immune response immune system process negative regulation of type 2 immune response arginase activity arginase activity cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion arginine metabolic process striated muscle contraction hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines arginine catabolic process to ornithine arginine catabolic process to ornithine manganese ion binding regulation of interleukin-1 beta production negative regulation of interleukin-13 production negative regulation of interleukin-17 production negative regulation of tumor necrosis factor production negative regulation of tumor necrosis factor production innate immune response negative regulation of striated muscle contraction metal ion binding nitric-oxide synthase binding negative regulation of macrophage inflammatory protein 1 alpha production negative regulation of chemokine (C-C motif) ligand 4 production negative regulation of chemokine (C-C motif) ligand 5 production negative regulation of defense response to bacterium regulation of reactive oxygen species biosynthetic process negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process regulation of L-arginine import across plasma membrane negative regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of cellular senescence |
00330 01100 05146 |
| 1448605_at |
Rhoc |
ras homolog family member C |
3 |
104789033 |
NM_007484 |
11853 |
46 |
nucleotide binding mitotic cytokinesis mitotic cytokinesis GTPase activity GTPase activity protein binding GTP binding GTP binding nucleus cytosol cytosol plasma membrane plasma membrane plasma membrane actin filament organization signal transduction small GTPase-mediated signal transduction membrane protein kinase binding positive regulation of cell migration positive regulation of protein-containing complex assembly cleavage furrow stereocilium regulation of actin cytoskeleton organization apical junction assembly apical junction assembly positive regulation of stress fiber assembly positive regulation of lipase activity |
|
| 1450897_at |
Arhgap5 |
Rho GTPase activating protein 5 |
12 |
52516076 |
BM248774 |
11855 |
40 |
positive regulation of mesenchymal cell proliferation GTPase activity GTPase activator activity GTPase activator activity GTP binding cytoplasm endoplasmic reticulum cytosol cytosol plasma membrane signal transduction Rho protein signal transduction regulation of cell size regulation of cell size epithelial cell migration positive regulation of epithelial cell migration membrane cell migration mammary gland development SH2 domain binding |
04510 04670 |
| 1416735_at |
Asah1 |
N-acylsphingosine amidohydrolase 1 |
8 |
-41340645 |
NM_019734 |
11886 |
64 |
transcription corepressor activity extracellular region extracellular space nucleus nucleus lysosome lipid metabolic process fatty acid metabolic process sphingolipid metabolic process response to organic substance hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides nuclear receptor binding N-acylsphingosine amidohydrolase activity N-acylsphingosine amidohydrolase activity N-acylsphingosine amidohydrolase activity fatty acid amide hydrolase activity keratinocyte differentiation lung development sphingosine biosynthetic process sphingosine biosynthetic process ceramide biosynthetic process ceramide catabolic process ceramide catabolic process ceramide catabolic process regulation of steroid biosynthetic process regulation of programmed necrotic cell death cellular response to tumor necrosis factor ceramidase activity |
00600 01100 04142 |
| 1429123_at |
Rab27a |
RAB27A, member RAS oncogene family |
9 |
73064147, 73044809 |
BB025283 |
11891 |
157 |
nucleotide binding photoreceptor outer segment GTPase activity GTPase activity G protein activity protein binding GTP binding GTP binding GTP binding intracellular anatomical structure lysosome endosome late endosome Golgi apparatus Golgi apparatus exocytosis exocytosis blood coagulation protein secretion positive regulation of gene expression membrane vesicle-mediated transport apical plasma membrane apical plasma membrane hydrolase activity GDP binding antigen processing and presentation protein domain specific binding secretory granule secretory granule secretory granule melanocyte differentiation dendrite myosin V binding melanosome localization melanosome transport multivesicular body membrane Weibel-Palade body multivesicular body organization melanosome melanosome melanosome cytotoxic T cell degranulation natural killer cell degranulation pigmentation positive regulation of exocytosis positive regulation of exocytosis positive regulation of phagocytosis pigment granule localization pigment granule transport exocytic vesicle exocytic vesicle multivesicular body sorting pathway complement-dependent cytotoxicity positive regulation of regulated secretory pathway positive regulation of reactive oxygen species biosynthetic process positive regulation of constitutive secretory pathway exosomal secretion |
|
| 1421205_at |
Atm |
ataxia telangiectasia mutated |
9 |
-53437121 |
NM_007499 |
11920 |
660 |
DNA damage checkpoint signaling DNA damage checkpoint signaling DNA damage checkpoint signaling nucleotide binding pexophagy telomere maintenance double-strand break repair via homologous recombination chromosome, telomeric region ovarian follicle development response to hypoxia somitogenesis pre-B cell allelic exclusion immune system process immunoglobulin production DNA binding protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity DNA-dependent protein kinase activity protein binding ATP binding nucleus nucleus nucleus nucleus nucleoplasm nucleoplasm nucleolus cytoplasm peroxisome peroxisomal matrix centrosome spindle cytoskeleton DNA repair DNA repair protein phosphorylation protein phosphorylation protein phosphorylation DNA damage response DNA damage response DNA damage response cell cycle mitotic spindle assembly checkpoint signaling mitotic G2 DNA damage checkpoint signaling male meiotic nuclear division female meiotic nuclear division female gamete generation brain development heart development determination of adult lifespan female gonad development intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage post-embryonic development response to ionizing radiation response to ionizing radiation regulation of autophagy regulation of autophagy positive regulation of gene expression kinase activity 1-phosphatidylinositol-3-kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation positive regulation of cell migration negative regulation of B cell proliferation cytoplasmic vesicle regulation of telomere maintenance via telomerase positive regulation of telomere maintenance via telomerase V(D)J recombination cellular response to reactive oxygen species multicellular organism growth histone H2AXS139 kinase activity peptidyl-serine autophosphorylation lipoprotein catabolic process signal transduction in response to DNA damage identical protein binding positive regulation of apoptotic process intracellular membrane-bounded organelle positive regulation of DNA damage response, signal transduction by p53 class mediator positive regulation of neuron apoptotic process positive regulation of neuron apoptotic process protein-containing complex binding meiotic telomere clustering positive regulation of cell adhesion positive regulation of transcription by RNA polymerase II protein autophosphorylation thymus development oocyte development neuron apoptotic process regulation of cell cycle chromosome organization involved in meiotic cell cycle histone mRNA catabolic process cellular response to retinoic acid cellular response to ionizing radiation cellular response to gamma radiation cellular response to X-ray cellular response to nitrosative stress replicative senescence establishment of RNA localization to telomere establishment of protein-containing complex localization to telomere positive regulation of DNA catabolic process regulation of microglial cell activation negative regulation of TORC1 signaling negative regulation of TORC1 signaling negative regulation of TORC1 signaling negative regulation of telomere capping positive regulation of telomere maintenance via telomere lengthening positive regulation of telomerase catalytic core complex assembly DNA repair complex |
04110 04115 04210 |
| 1439036_a_at |
Atp1b1 |
ATPase, Na+/K+ transporting, beta 1 polypeptide |
1 |
-164437098 |
AV152334 |
11931 |
93 |
response to hypoxia ATPase activator activity ATPase activator activity ATPase activator activity blastocyst development P-type sodium:potassium-exchanging transporter activity protein binding plasma membrane plasma membrane sodium:potassium-exchanging ATPase complex sodium:potassium-exchanging ATPase complex sodium:potassium-exchanging ATPase complex caveola monoatomic ion transport potassium ion transport sodium ion transport intracellular calcium ion homeostasis intracellular sodium ion homeostasis intracellular sodium ion homeostasis cell adhesion establishment or maintenance of transmembrane electrochemical gradient regulation of gene expression regulation of cardiac muscle contraction by calcium ion signaling intercalated disc membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane apical plasma membrane lateral plasma membrane protein kinase binding metal ion transport intracellular potassium ion homeostasis intracellular potassium ion homeostasis T-tubule protein-macromolecule adaptor activity organelle membrane positive regulation of ATP-dependent activity sodium ion transmembrane transport sperm flagellum sodium ion export across plasma membrane sodium ion export across plasma membrane sodium ion export across plasma membrane sarcolemma myelin sheath ATP metabolic process protein heterodimerization activity protein stabilization protein stabilization ATPase binding relaxation of cardiac muscle cardiac muscle contraction protein localization to plasma membrane membrane repolarization monoatomic cation transmembrane transport positive regulation of potassium ion transmembrane transporter activity proton transmembrane transport regulation of calcium ion transmembrane transport positive regulation of sodium ion export across plasma membrane positive regulation of calcium:sodium antiporter activity positive regulation of potassium ion import across plasma membrane positive regulation of P-type sodium:potassium-exchanging transporter activity positive regulation of P-type sodium:potassium-exchanging transporter activity potassium ion import across plasma membrane potassium ion import across plasma membrane |
04260 04960 04964 04970 04971 04972 04973 04974 04976 |
| 1423126_at |
Atp1b3 |
ATPase, Na+/K+ transporting, beta 3 polypeptide |
9 |
-96332655, -96332655 |
BI080505 |
11933 |
32 |
ATPase activator activity ATPase activator activity P-type sodium:potassium-exchanging transporter activity protein binding cytoplasm plasma membrane sodium:potassium-exchanging ATPase complex sodium:potassium-exchanging ATPase complex caveola monoatomic ion transport potassium ion transport sodium ion transport intracellular sodium ion homeostasis intracellular sodium ion homeostasis membrane basolateral plasma membrane apical plasma membrane metal ion transport intracellular potassium ion homeostasis intracellular potassium ion homeostasis protein-macromolecule adaptor activity positive regulation of ATP-dependent activity sodium ion transmembrane transport sperm flagellum sodium ion export across plasma membrane sodium ion export across plasma membrane protein stabilization ATPase binding potassium ion transmembrane transport protein localization to plasma membrane membrane repolarization positive regulation of potassium ion transmembrane transporter activity positive regulation of sodium ion export across plasma membrane positive regulation of potassium ion import across plasma membrane potassium ion import across plasma membrane potassium ion import across plasma membrane |
04260 04960 04964 04970 04971 04972 04973 04974 04976 |
| 1438809_at |
Atp5f1c |
ATP synthase F1 subunit gamma |
2 |
-10056030, -10056030 |
AI644507 |
11949 |
53 |
mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) protein binding mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial proton-transporting ATP synthase complex ATP biosynthetic process monoatomic ion transport proton motive force-driven ATP synthesis proton motive force-driven ATP synthesis membrane ATP hydrolysis activity proton motive force-driven mitochondrial ATP synthesis myelin sheath proton-transporting ATP synthase complex, catalytic core F(1) proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATP synthase activity, rotational mechanism proton transmembrane transport |
00190 01100 05010 05012 05016 |
| 1422508_at |
Atp6v1a |
ATPase, H+ transporting, lysosomal V1 subunit A |
16 |
-44085403 |
NM_007508 |
11964 |
50 |
nucleotide binding vacuolar proton-transporting V-type ATPase, V1 domain ATP binding nucleoplasm cytoplasm mitochondrion lysosome cytosol cytosol plasma membrane microvillus monoatomic ion transport intracellular iron ion homeostasis membrane apical plasma membrane ATP hydrolysis activity secretory granule cytoplasmic vesicle proton-transporting V-type ATPase complex proton-transporting V-type ATPase, V1 domain cellular response to increased oxygen levels myelin sheath intracellular membrane-bounded organelle ATP metabolic process proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism synaptic vesicle lumen acidification synaptic vesicle lumen acidification synaptic vesicle lumen acidification extrinsic component of synaptic vesicle membrane transmembrane transporter complex proton transmembrane transport proton transmembrane transport ATPase complex |
00190 01100 04145 04966 05323 |
| 1436515_at |
Bach2 |
BTB and CNC homology, basic leucine zipper transcription factor 2 |
4 |
32417434 |
BB529913 |
12014 |
101 |
negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm cytoplasm cytosol regulation of DNA-templated transcription regulation of transcription by RNA polymerase II ion binding import into nucleus RNA polymerase II transcription regulator complex primary adaptive immune response involving T cells and B cells sequence-specific double-stranded DNA binding |
|
| 1440770_at |
Bcl2 |
B cell leukemia/lymphoma 2 |
1 |
-106538175, -106712164 |
AI505544 |
12043 |
792 |
G1/S transition of mitotic cell cycle protein polyubiquitination mitotic cell cycle cell morphogenesis cell morphogenesis response to acid chemical ossification ovarian follicle development metanephros development ureteric bud development branching involved in ureteric bud morphogenesis branching involved in ureteric bud morphogenesis behavioral fear response leukocyte homeostasis B cell homeostasis B cell apoptotic process B cell apoptotic process kidney development kidney development release of cytochrome c from mitochondria regulation of cell-matrix adhesion protease binding lymphocyte homeostasis lymphocyte homeostasis lymphoid progenitor cell differentiation B cell lineage commitment T cell lineage commitment immune system development negative regulation of B cell apoptotic process response to ischemia renal system process protein binding intracellular anatomical structure nucleus nucleus cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane cytosol protein dephosphorylation melanin metabolic process regulation of nitrogen utilization intracellular calcium ion homeostasis apoptotic process apoptotic process DNA damage response response to oxidative stress actin filament organization axonogenesis transcription factor binding cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation male gonad development extrinsic apoptotic signaling pathway via death domain receptors intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to oxidative stress apoptotic mitochondrial changes response to xenobiotic stimulus response to xenobiotic stimulus response to toxic substance response to toxic substance post-embryonic development post-embryonic development post-embryonic development animal organ morphogenesis response to iron ion response to UV-B response to gamma radiation regulation of gene expression regulation of autophagy negative regulation of autophagy negative regulation of autophagy negative regulation of calcium ion transport into cytosol regulation of glycoprotein biosynthetic process negative regulation of cardiac muscle cell apoptotic process mesenchymal cell development positive regulation of neuron maturation smooth muscle cell migration positive regulation of smooth muscle cell migration channel activity membrane membrane cell growth channel inhibitor activity cell migration peptidyl-serine phosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation protein phosphatase binding cochlear nucleus development gland morphogenesis regulation of transmembrane transporter activity mitochondrial crista hemopoiesis B cell differentiation T cell differentiation T cell differentiation negative regulation of ossification positive regulation of cell growth negative regulation of cell growth melanocyte differentiation melanocyte differentiation negative regulation of cell migration positive regulation of B cell proliferation hair follicle morphogenesis axon regeneration ubiquitin protein ligase binding regulation of protein stability nuclear membrane nuclear membrane mitochondrial membrane endoplasmic reticulum calcium ion homeostasis glomerulus development negative regulation of cellular pH reduction regulation of protein localization protein-containing complex myeloid cell apoptotic process negative regulation of myeloid cell apoptotic process T cell differentiation in thymus positive regulation of peptidyl-serine phosphorylation osteoblast proliferation negative regulation of osteoblast proliferation response to cytokine response to cytokine response to nicotine organ growth regulation of growth positive regulation of multicellular organism growth B cell proliferation cellular response to glucose starvation response to hydrogen peroxide neuron maturation identical protein binding protein homodimerization activity regulation of apoptotic process T cell homeostasis T cell homeostasis negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process regulation of programmed cell death positive regulation of catalytic activity myelin sheath CD8-positive, alpha-beta T cell lineage commitment pigmentation negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process ear development ear development protein-containing complex binding regulation of viral genome replication response to ethanol positive regulation of melanocyte differentiation negative regulation of mitotic cell cycle retinal cell programmed cell death negative regulation of retinal cell programmed cell death regulation of mitochondrial membrane permeability pore complex protein heterodimerization activity protein heterodimerization activity focal adhesion assembly developmental pigmentation developmental pigmentation developmental pigmentation regulation of developmental pigmentation positive regulation of developmental pigmentation positive regulation of developmental pigmentation perinuclear region of cytoplasm spleen development spleen development thymus development thymus development response to steroid hormone digestive tract morphogenesis developmental growth oocyte development skeletal muscle fiber development positive regulation of skeletal muscle fiber development pigment granule organization stem cell development homeostasis of number of cells within a tissue regulation of catalytic activity B cell receptor signaling pathway response to glucocorticoid response to glucocorticoid BH domain binding neuron apoptotic process neuron apoptotic process neuron apoptotic process BH3 domain binding defense response to virus establishment of localization in cell protein phosphatase 2A binding regulation of cell cycle regulation of mitochondrial membrane potential regulation of calcium ion transport molecular adaptor activity hematopoietic stem cell differentiation calcium ion transport into cytosol intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress lymphocyte apoptotic process negative regulation of lymphocyte apoptotic process T cell apoptotic process T cell apoptotic process negative regulation of T cell apoptotic process cellular response to organic substance cellular response to hypoxia reactive oxygen species metabolic process dendritic cell apoptotic process motor neuron apoptotic process BAD-BCL-2 complex extrinsic apoptotic signaling pathway in absence of ligand extrinsic apoptotic signaling pathway in absence of ligand cell-cell adhesion DNA-binding transcription factor binding epithelial cell apoptotic process negative regulation of epithelial cell apoptotic process negative regulation of G1/S transition of mitotic cell cycle negative regulation of G1/S transition of mitotic cell cycle negative regulation of reactive oxygen species metabolic process negative regulation of dendritic cell apoptotic process negative regulation of motor neuron apoptotic process negative regulation of anoikis negative regulation of apoptotic signaling pathway negative regulation of apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative regulation of intrinsic apoptotic signaling pathway negative regulation of intrinsic apoptotic signaling pathway |
04141 04210 04510 04722 05014 05145 05200 05210 05215 05222 |
| 1418133_at |
Bcl3 |
B cell leukemia/lymphoma 3 |
7 |
-19808461 |
NM_033601 |
12051 |
93 |
follicular dendritic cell differentiation marginal zone B cell differentiation humoral immune response mediated by circulating immunoglobulin germinal center formation transcription coactivator activity transcription corepressor activity protein binding nucleus nucleus nucleoplasm cytoplasm cytosol plasma membrane protein import into nucleus DNA damage response canonical NF-kappaB signal transduction response to virus response to UV-C antimicrobial humoral response extracellular matrix organization DNA damage response, signal transduction by p53 class mediator midbody protein-macromolecule adaptor activity negative regulation of NF-kappaB transcription factor activity type II interferon production negative regulation of interleukin-8 production negative regulation of tumor necrosis factor production positive regulation of type II interferon production positive regulation of interleukin-10 production protein-containing complex Bcl3-Bcl10 complex Bcl3/NF-kappaB2 complex Bcl3/NF-kappaB2 complex T-helper 1 type immune response defense response to bacterium intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator histone deacetylase binding histone deacetylase binding defense response to protozoan regulation of apoptotic process regulation of apoptotic process negative regulation of apoptotic process intracellular membrane-bounded organelle T-helper 2 cell differentiation positive regulation of translation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of receptor signaling pathway via JAK-STAT spleen development T cell apoptotic process T cell apoptotic process negative regulation of T cell apoptotic process negative regulation of T cell apoptotic process DNA-binding transcription factor binding DNA-binding transcription factor binding |
|
| 1450624_at |
Bhmt |
betaine-homocysteine methyltransferase |
13 |
-93616890 |
NM_016668 |
12116 |
46 |
nucleus cytosol cytosol amino-acid betaine metabolic process methyltransferase activity zinc ion binding methionine biosynthetic process methionine biosynthetic process protein-containing complex identical protein binding protein-containing complex binding betaine-homocysteine S-methyltransferase activity betaine-homocysteine S-methyltransferase activity betaine-homocysteine S-methyltransferase activity extracellular exosome 'de novo' L-methionine biosynthetic process L-methionine salvage L-methionine salvage |
00260 00270 01100 |
| 1450779_at |
Fabp7 |
fatty acid binding protein 7, brain |
10 |
57784922 |
NM_021272 |
12140 |
376 |
startle response fatty acid binding fatty acid binding nucleus cytoplasm cytosol cytosol cell-cell junction lipid binding fatty acid transport cell proliferation in forebrain neurogenesis cell projection neuronal cell body epithelial cell proliferation prepulse inhibition cell periphery |
03320 |
| 1422775_at |
Blk |
B lymphoid kinase |
14 |
-63372836 |
NM_007549 |
12143 |
44 |
nucleotide binding protein kinase activity protein tyrosine kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity signaling receptor binding protein binding ATP binding cytosol plasma membrane protein phosphorylation protein phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway membrane kinase activity phosphorylation transferase activity peptidyl-tyrosine phosphorylation cell differentiation positive regulation of insulin secretion positive regulation of protein binding innate immune response B cell receptor signaling pathway |
|
| 1422003_at |
Cxcr5 |
C-X-C motif chemokine receptor 5 |
9 |
-44511786 |
NM_007551 |
12145 |
159 |
G protein-coupled receptor activity plasma membrane chemotaxis immune response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration external side of plasma membrane external side of plasma membrane membrane C-C chemokine receptor activity C-X-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding leukocyte chemotaxis positive regulation of cytokinesis B cell activation lymph node development cell chemotaxis |
04060 04062 |
| 1448733_at |
Bmi1 |
Bmi1 polycomb ring finger oncogene |
2 |
18677017 |
M64279 |
12151 |
354 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II ubiquitin ligase complex heterochromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding skeletal system development in utero embryonic development chromatin binding protein binding nucleus cytoplasm cytosol DNA methylation chromatin organization chromatin organization humoral immune response brain development zinc ion binding nuclear body nuclear body rostrocaudal neural tube patterning positive regulation of B cell proliferation PcG protein complex PcG protein complex positive regulation of immature T cell proliferation in thymus PRC1 complex PRC1 complex PRC1 complex sequence-specific DNA binding metal ion binding somatic stem cell division embryonic skeletal system morphogenesis embryonic skeletal system development hematopoietic stem cell homeostasis RING-like zinc finger domain binding ubiquitin-protein transferase activator activity apoptotic signaling pathway promoter-specific chromatin binding promoter-specific chromatin binding promoter-specific chromatin binding regulation of adaxial/abaxial pattern formation negative regulation of apoptotic signaling pathway |
|
| 1422084_at |
Bmx |
BMX non-receptor tyrosine kinase |
X |
-164192841 |
AF012104 |
12169 |
37 |
nucleotide binding adaptive immune response protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity ATP binding nucleoplasm cytoplasm plasma membrane plasma membrane protein phosphorylation protein phosphorylation apoptotic process cell adhesion signal transduction kinase activity phosphorylation transferase activity ruffle membrane intracellular signal transduction protein autophosphorylation metal ion binding B cell receptor signaling pathway |
|
| 1449453_at |
Bst1 |
bone marrow stromal cell antigen 1 |
5 |
43818892 |
AI647987 |
12182 |
39 |
uropod regulation of cell-matrix adhesion NAD+ nucleosidase activity NAD+ nucleosidase activity plasma membrane plasma membrane positive regulation of cell population proliferation membrane transferase activity hydrolase activity phosphorus-oxygen lyase activity positive regulation of B cell proliferation regulation of actin cytoskeleton organization NADP+ nucleosidase activity regulation of inflammatory response regulation of peptidyl-tyrosine phosphorylation regulation of calcium-mediated signaling NAD+ nucleotidase, cyclic ADP-ribose generating regulation of neutrophil chemotaxis side of membrane |
00760 01100 04020 04970 04972 |
| 1450644_at |
Zfp36l1 |
zinc finger protein 36, C3H type-like 1 |
12 |
-80107759 |
M58566 |
12192 |
57 |
MAPK cascade MAPK cascade MAPK cascade nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay P-body vasculogenesis proepicardium development DNA binding RNA binding mRNA binding mRNA binding protein binding nucleus nucleus cytoplasm cytoplasm cytosol mRNA processing mRNA catabolic process regulation of translation apoptotic process multicellular organism development heart development cell population proliferation response to wounding regulation of gene expression regulation of keratinocyte proliferation neural tube development nuclear-transcribed mRNA catabolic process, deadenylation-independent decay regulation of mRNA 3'-end processing cellular response to insulin stimulus T cell differentiation in thymus T cell differentiation in thymus multicellular organism growth mRNA 3'-UTR AU-rich region binding mRNA 3'-UTR AU-rich region binding mRNA 3'-UTR AU-rich region binding p38MAPK cascade regulation of mRNA stability regulation of mRNA stability regulation of mRNA stability phosphatidylinositol 3-kinase/protein kinase B signal transduction phosphatidylinositol 3-kinase/protein kinase B signal transduction cellular response to fibroblast growth factor stimulus regulation of B cell differentiation positive regulation of fat cell differentiation regulation of keratinocyte differentiation negative regulation of erythrocyte differentiation positive regulation of monocyte differentiation regulation of myoblast differentiation metal ion binding mesendoderm development embryonic organ development mRNA transport chorio-allantoic fusion spongiotrophoblast layer development 3'-UTR-mediated mRNA destabilization 3'-UTR-mediated mRNA destabilization 3'-UTR-mediated mRNA destabilization ERK1 and ERK2 cascade cellular response to cAMP cellular response to cAMP cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus cellular response to peptide hormone stimulus cellular response to peptide hormone stimulus cellular response to glucocorticoid stimulus cellular response to hypoxia cellular response to salt stress cellular response to transforming growth factor beta stimulus 14-3-3 protein binding regulation of stem cell proliferation cellular response to raffinose positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay negative regulation of mitotic cell cycle phase transition regulation of keratinocyte apoptotic process positive regulation of intracellular mRNA localization ribonucleoprotein complex ribonucleoprotein complex ribonucleoprotein complex |
|
| 1451021_a_at |
Klf5 |
Kruppel-like transcription factor 5 |
14 |
99298690 |
BI465857 |
12224 |
179 |
negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific angiogenesis DNA binding DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm nucleoplasm transcription regulator complex Golgi apparatus regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of gene expression skeletal muscle satellite cell differentiation satellite cell activation involved in skeletal muscle regeneration myotube differentiation involved in skeletal muscle regeneration myotube differentiation involved in skeletal muscle regeneration microvillus assembly regulation of microvillus assembly skeletal muscle cell differentiation intracellular membrane-bounded organelle skeletal muscle tissue regeneration MRF binding sequence-specific DNA binding positive regulation of fat cell differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding intestinal epithelial cell development positive regulation of transcription by transcription factor localization cell-cell signaling via exosome positive regulation of miRNA transcription cellular response to leukemia inhibitory factor sequence-specific double-stranded DNA binding |
|
| 1442018_at |
Btg1 |
BTG anti-proliferation factor 1 |
10 |
96617000 |
BE632903 |
12226 |
50 |
nucleus nucleus cytoplasm cytoplasm protein methylation cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation enzyme binding positive regulation of catalytic activity positive regulation of endothelial cell differentiation positive regulation of myoblast differentiation positive regulation of angiogenesis negative regulation of mitotic cell cycle positive regulation of fibroblast apoptotic process |
03018 |
| 1438948_x_at |
Tspo |
translocator protein |
15 |
83563572 |
AV101079 |
12257 |
142 |
androgen binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane endoplasmic reticulum cytosol steroid biosynthetic process monoatomic ion transport chloride transport lipid transport glial cell migration benzodiazepine receptor activity negative regulation of mitochondrion organization cholesterol binding membrane negative regulation of protein ubiquitination negative regulation of tumor necrosis factor production cholesterol homeostasis positive regulation of apoptotic process intracellular membrane-bounded organelle transmembrane transporter binding negative regulation of nitric oxide biosynthetic process behavioral response to pain regulation of steroid biosynthetic process positive regulation of mitochondrial depolarization positive regulation of calcium ion transport contact inhibition positive regulation of glial cell proliferation negative regulation of glial cell proliferation positive regulation of programmed necrotic cell death establishment of protein localization to mitochondrion maintenance of protein location in mitochondrion negative regulation of mitophagy negative regulation of ATP metabolic process response to acetylcholine positive regulation of reactive oxygen species metabolic process positive regulation of reactive oxygen species metabolic process negative regulation of corticosterone secretion |
04080 |
| 1416625_at |
Serping1 |
serine (or cysteine) peptidase inhibitor, clade G, member 1 |
2 |
-84765359 |
NM_009776 |
12258 |
43 |
complement binding negative regulation of complement activation, lectin pathway immune system process serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity extracellular region extracellular space extracellular space extracellular space extracellular space complement activation, classical pathway blood coagulation hemostasis negative regulation of peptidase activity negative regulation of endopeptidase activity peptidase inhibitor activity fibrinolysis innate immune response collagen-containing extracellular matrix |
04610 |
| 1449401_at |
C1qc |
complement component 1, q subcomponent, C chain |
4 |
-136889801 |
NM_007574 |
12262 |
34 |
immune system process extracellular region extracellular region collagen trimer complement component C1 complex extracellular space complement activation, classical pathway complement activation, classical pathway negative regulation of granulocyte differentiation innate immune response synapse synapse synapse negative regulation of macrophage differentiation complement component C1q complex postsynapse synapse pruning |
04610 05020 05142 05150 05322 |
| 1421211_a_at |
Ciita |
class II transactivator |
16 |
10480071, 10489780, 10488177 |
AF042158 |
12265 |
187 |
negative regulation of transcription by RNA polymerase II nucleotide binding transcription cis-regulatory region binding protein serine/threonine kinase activity protein binding ATP binding GTP binding nucleus nucleoplasm cytosol regulation of DNA-templated transcription cell surface kinase activity phosphorylation PML body transferase activity acyltransferase activity response to type II interferon response to type II interferon protein-containing complex binding positive regulation of MHC class I biosynthetic process positive regulation of MHC class I biosynthetic process positive regulation of MHC class II biosynthetic process positive regulation of MHC class II biosynthetic process negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of viral entry into host cell response to antibiotic DNA-binding transcription factor binding |
04612 05145 05340 |
| 1423954_at |
C3 |
complement component 3 |
17 |
-57203966 |
K02782 |
12266 |
681 |
positive regulation of type IIa hypersensitivity positive regulation of protein phosphorylation positive regulation of activation of membrane attack complex immune system process complement receptor mediated signaling pathway endopeptidase inhibitor activity protein binding extracellular region extracellular space extracellular space extracellular space extracellular space lipid metabolic process fatty acid metabolic process inflammatory response complement activation complement activation complement activation complement activation complement activation, alternative pathway complement activation, classical pathway lipid binding response to bacterium cell surface positive regulation of vascular endothelial growth factor production positive regulation of glucose transmembrane transport regulation of triglyceride biosynthetic process positive regulation of lipid storage neuron remodeling C5L2 anaphylatoxin chemotactic receptor binding protein-containing complex oviduct epithelium development vascular associated smooth muscle cell differentiation innate immune response positive regulation of G protein-coupled receptor signaling pathway positive regulation of angiogenesis positive regulation of receptor-mediated endocytosis positive regulation of receptor-mediated endocytosis positive regulation of developmental growth positive regulation of phagocytosis retina development in camera-type eye positive regulation of phagocytosis, engulfment positive regulation of phagocytosis, engulfment positive regulation of ERK1 and ERK2 cascade amyloid-beta clearance amyloid-beta clearance complement-dependent cytotoxicity complement-mediated synapse pruning vertebrate eye-specific patterning positive regulation of apoptotic cell clearance |
04145 04610 05140 05142 05150 05322 |
| 1439902_at |
C5ar1 |
complement component 5a receptor 1 |
7 |
-16246742, -16246744 |
BB552085 |
12273 |
290 |
microglial cell activation complement component C5a binding complement receptor mediated signaling pathway complement receptor activity complement component C5a receptor activity complement component C5a receptor activity complement component C5a receptor activity G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane chemotaxis inflammatory response signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration cell surface positive regulation of vascular endothelial growth factor production positive regulation of macrophage chemotaxis membrane basolateral plasma membrane cell proliferation in hindbrain neutrophil chemotaxis cytoplasmic vesicle response to peptidoglycan complement component C5a signaling pathway mRNA transcription by RNA polymerase II negative regulation of neuron apoptotic process apical part of cell positive regulation of angiogenesis astrocyte activation positive regulation of epithelial cell proliferation defense response to Gram-positive bacterium cognition positive regulation of ERK1 and ERK2 cascade positive regulation of neutrophil chemotaxis amyloid-beta clearance presynapse organization regulation of tau-protein kinase activity |
04080 04610 05150 |
| 1419091_a_at |
Anxa2 |
annexin A2 |
9 |
69453682 |
NM_007585 |
12306 |
171 |
angiogenesis cornified envelope stress fiber ruffle phosphatidylserine binding positive regulation of receptor recycling positive regulation of protein phosphorylation protease binding phospholipase inhibitor activity serine-type endopeptidase inhibitor activity calcium ion binding protein binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding phosphatidylinositol-4,5-bisphosphate binding extracellular region basement membrane extracellular space cytoplasm cytoplasm cytoplasm lysosomal membrane endosome early endosome lipid droplet cytosol cytosol cytosol plasma membrane plasma membrane plasma membrane cell cortex cell adhesion cell-matrix adhesion body fluid secretion cytoskeletal protein binding cell surface cell surface response to activity membrane membrane basolateral plasma membrane nuclear matrix phospholipase A2 inhibitor activity cell junction collagen fibril organization lung development midbody small GTPase binding late endosome membrane vesicle negative regulation of low-density lipoprotein particle receptor catabolic process protein-containing complex myelin sheath adaxonal region sarcolemma fibrinolysis mRNA transcription by RNA polymerase II identical protein binding Schmidt-Lanterman incisure macropinosome S100 protein binding bone sialoprotein binding membrane raft positive regulation of exocytosis positive regulation of transcription by RNA polymerase II positive regulation of fibroblast proliferation calcium-dependent protein binding perinuclear region of cytoplasm regulation of neurogenesis positive regulation of binding collagen-containing extracellular matrix extracellular exosome cellular response to acid chemical protein localization to plasma membrane RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex plasma membrane protein complex plasma membrane protein complex plasma membrane protein complex epithelial cell apoptotic process positive regulation of low-density lipoprotein particle clearance positive regulation of low-density lipoprotein particle receptor binding positive regulation of low-density lipoprotein receptor activity positive regulation of receptor-mediated endocytosis involved in cholesterol transport positive regulation of receptor-mediated endocytosis involved in cholesterol transport positive regulation of plasma membrane repair AnxA2-p11 complex PCSK9-AnxA2 complex |
|
| 1423097_s_at |
Capn7 |
calpain 7 |
14 |
31336637 |
BQ257745 |
12339 |
23 |
endopeptidase activity cysteine-type endopeptidase activity calcium-dependent cysteine-type endopeptidase activity nucleus centrosome cytosol proteolysis proteolysis peptidase activity cysteine-type peptidase activity positive regulation of epithelial cell migration hydrolase activity MIT domain binding self proteolysis |
|
| 1449434_at |
Car3 |
carbonic anhydrase 3 |
3 |
14863537 |
NM_007606 |
12350 |
68 |
carbonate dehydratase activity carbonate dehydratase activity cytoplasm cytoplasm cytosol cytosol cytosol one-carbon metabolic process response to oxidative stress zinc ion binding response to bacterium nickel cation binding phosphatase activity lyase activity metal ion binding |
00910 |
| 1448949_at |
Car4 |
carbonic anhydrase 4 |
11 |
84957753 |
NM_007607 |
12351 |
66 |
carbonate dehydratase activity carbonate dehydratase activity carbonate dehydratase activity protein binding rough endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment Golgi apparatus trans-Golgi network plasma membrane plasma membrane plasma membrane one-carbon metabolic process regulation of pH zinc ion binding external side of plasma membrane cell surface carbon dioxide transport bicarbonate transport membrane apical plasma membrane sarcoplasmic reticulum lyase activity transport vesicle membrane secretory granule membrane brush border membrane sarcolemma metal ion binding perinuclear region of cytoplasm extracellular exosome side of membrane |
00910 |
| 1449265_at |
Casp1 |
caspase 1 |
9 |
5298516 |
BC008152 |
12362 |
965 |
response to hypoxia response to hypoxia microglial cell activation positive regulation of cytokine production positive regulation of cytokine production pattern recognition receptor signaling pathway endopeptidase activity cysteine-type endopeptidase activity cysteine-type endopeptidase activity protein binding extracellular region cytoplasm cytoplasm cytoplasm cytoplasm cytosol cytosol cytosol microtubule plasma membrane proteolysis apoptotic process osmosensory signaling pathway myoblast fusion memory peptidase activity cysteine-type peptidase activity response to xenobiotic stimulus response to bacterium regulation of autophagy macrophage cytokine production response to organic cyclic compound membrane protein processing protein processing protein autoprocessing protein autoprocessing hydrolase activity kinase binding response to lipopolysaccharide response to lipopolysaccharide interleukin-1 alpha production interleukin-1 beta production interleukin-1 beta production positive regulation of interleukin-1 alpha production positive regulation of interleukin-1 alpha production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-18 production protein-containing complex response to ATP defense response to bacterium identical protein binding regulation of apoptotic process positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of circadian sleep/wake cycle, non-REM sleep CARD domain binding regulation of inflammatory response regulation of inflammatory response regulation of inflammatory response positive regulation of inflammatory response positive regulation of inflammatory response positive regulation of inflammatory response defense response to Gram-negative bacterium protein maturation protein maturation defense response to virus mitochondrial depolarization membrane hyperpolarization positive regulation of macrophage cytokine production canonical inflammasome complex pyroptosis pyroptosis pyroptosis pyroptosis cellular response to lipopolysaccharide cellular response to organic substance cellular response to type II interferon IPAF inflammasome complex IPAF inflammasome complex NLRP1 inflammasome complex NLRP1 inflammasome complex NLRP3 inflammasome complex NLRP3 inflammasome complex caspase binding scaffold protein binding AIM2 inflammasome complex AIM2 inflammasome complex protease inhibitor complex programmed necrotic cell death cytokine precursor processing signaling receptor ligand precursor processing AIM2 inflammasome complex assembly AIM2 inflammasome complex assembly positive regulation of tumor necrosis factor-mediated signaling pathway |
04621 04623 05014 |
| 1449591_at |
Casp4 |
caspase 4, apoptosis-related cysteine peptidase |
9 |
5308848, 5308859 |
NM_007609 |
12363 |
281 |
lipopolysaccharide binding lipopolysaccharide binding immune system process cysteine-type endopeptidase activity cysteine-type endopeptidase activity cysteine-type endopeptidase activity cysteine-type endopeptidase activity protein binding extracellular region cytoplasm cytoplasm mitochondrion endoplasmic reticulum cytosol cytosol plasma membrane proteolysis inflammatory response actin filament organization peptidase activity cysteine-type peptidase activity lipid binding macrophage cytokine production programmed cell death membrane protein autoprocessing protein autoprocessing hydrolase activity detection of lipopolysaccharide interleukin-1 beta production positive regulation of interleukin-1 beta production protein-containing complex ectopic germ cell programmed cell death ectopic germ cell programmed cell death defense response to bacterium defense response to bacterium regulation of apoptotic process neuronal cell body positive regulation of neuron apoptotic process innate immune response CARD domain binding regulation of inflammatory response positive regulation of inflammatory response positive regulation of inflammatory response positive regulation of inflammatory response defense response to Gram-positive bacterium protein maturation positive regulation of macrophage cytokine production positive regulation of macrophage cytokine production canonical inflammasome complex pyroptosis pyroptosis NLRP1 inflammasome complex NLRP1 inflammasome complex scaffold protein binding non-canonical inflammasome complex non-canonical inflammasome complex non-canonical inflammasome complex assembly non-canonical inflammasome complex assembly positive regulation of NLRP3 inflammasome complex assembly positive regulation of interleukin-18-mediated signaling pathway |
|
| 1433718_a_at |
Cbx1 |
chromobox 1 |
11 |
96789134, 96789134 |
BB224832 |
12412 |
107 |
negative regulation of transcription by RNA polymerase II chromosome, centromeric region chromosome, telomeric region chromatin chromatin female pronucleus male pronucleus DNA binding chromatin binding protein binding nucleus nucleus nucleoplasm pericentric heterochromatin pericentric heterochromatin spindle chromatin organization DNA damage response chromocenter nuclear body enzyme binding methylated histone binding identical protein binding intracellular membrane-bounded organelle negative regulation of DNA-templated transcription molecular adaptor activity site of DNA damage histone methyltransferase binding |
|
| 1419583_at |
Cbx4 |
chromobox 4 |
11 |
-119077570 |
NM_007625 |
12418 |
48 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding chromatin binding single-stranded RNA binding protein binding nucleus nucleus nucleoplasm nucleoplasm chromatin organization nuclear body nuclear body transferase activity protein sumoylation protein sumoylation SUMO transferase activity SUMO transferase activity enzyme binding PcG protein complex SUMO binding SUMO binding SUMO binding methylated histone binding PRC1 complex PRC1 complex negative regulation of DNA-templated transcription phosphoprotein binding SUMO ligase activity SUMO ligase activity |
|
| 1425837_a_at |
Noct |
nocturnin |
3 |
51224446 |
AF199491 |
12457 |
49 |
3'-5'-RNA exonuclease activity deadenylation-dependent decapping of nuclear-transcribed mRNA P-body RNA binding mRNA binding catalytic activity poly(A)-specific ribonuclease activity poly(A)-specific ribonuclease activity protein binding nucleus cytoplasm mitochondrion NADP metabolic process circadian rhythm response to extracellular stimulus negative regulation of gene expression hydrolase activity NADP phosphatase activity response to lipopolysaccharide circadian regulation of gene expression P-body assembly regulation of circadian rhythm positive regulation of fat cell differentiation negative regulation of osteoblast differentiation regulation of embryonic development metal ion binding mRNA stabilization perinuclear region of cytoplasm rhythmic process NADPH phosphatase activity |
|
| 1450357_a_at |
Ccr6 |
C-C motif chemokine receptor 6 |
17 |
8243806, 8236042, 8245057, 8242525 |
NM_009835 |
12458 |
182 |
leukocyte migration involved in inflammatory response G protein-coupled receptor activity chemokine receptor activity protein binding plasma membrane chemotaxis chemotaxis immune response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration external side of plasma membrane external side of plasma membrane cell surface cell surface positive regulation of epithelial cell migration membrane C-C chemokine receptor activity C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling calcium-mediated signaling C-C chemokine binding C-C chemokine binding C-C chemokine binding sperm flagellum sperm flagellum isotype switching to IgA isotypes cell chemotaxis cell chemotaxis positive regulation of flagellated sperm motility involved in capacitation positive regulation of flagellated sperm motility involved in capacitation lymphocyte migration T cell migration thymocyte migration thymocyte migration sperm midpiece sperm principal piece sperm principal piece sperm plasma membrane sperm plasma membrane DN2 thymocyte differentiation DN3 thymocyte differentiation regulation of T cell migration positive regulation of dendritic cell chemotaxis positive regulation of dendritic cell chemotaxis |
04060 04062 |
| 1417268_at |
Cd14 |
CD14 antigen |
18 |
-36725063 |
NM_009841 |
12475 |
285 |
lipopolysaccharide binding lipopolysaccharide binding positive regulation of cytokine production positive regulation of cytokine production lipopolysaccharide immune receptor activity response to molecule of bacterial origin immune system process cell surface pattern recognition receptor signaling pathway extracellular region extracellular space Golgi apparatus plasma membrane receptor-mediated endocytosis inflammatory response response to bacterium response to bacterium external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface membrane positive regulation of lipopolysaccharide-mediated signaling pathway positive regulation of type I interferon production positive regulation of type II interferon production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway positive regulation of toll-like receptor 4 signaling pathway response to tumor necrosis factor innate immune response membrane raft membrane raft membrane raft positive regulation of endocytosis lipopolysaccharide receptor complex lipopolysaccharide receptor complex lipoteichoic acid binding cellular response to molecule of bacterial origin cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipoteichoic acid cellular response to diacyl bacterial lipopeptide cellular response to triacyl bacterial lipopeptide side of membrane |
04010 04145 04620 04640 04810 05146 |
| 1450570_a_at |
Cd19 |
CD19 antigen |
7 |
-126408447 |
NM_009844 |
12478 |
836 |
B-1 B cell differentiation adaptive immune response B cell proliferation involved in immune response immune system process plasma membrane plasma membrane plasma membrane external side of plasma membrane external side of plasma membrane external side of plasma membrane membrane immunoglobulin mediated immune response B cell mediated immunity protein-containing complex antigen receptor-mediated signaling pathway B cell receptor signaling pathway B cell receptor signaling pathway B cell receptor signaling pathway regulation of B cell receptor signaling pathway regulation of B cell receptor signaling pathway regulation of B cell activation positive regulation of release of sequestered calcium ion into cytosol positive regulation of release of sequestered calcium ion into cytosol positive regulation of release of sequestered calcium ion into cytosol positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
04640 04662 05340 |
| 1418770_at |
Cd2 |
CD2 antigen |
3 |
-101275907 |
NM_013486 |
12481 |
72 |
signaling receptor binding signaling receptor binding protein binding extracellular region nucleoplasm Golgi apparatus plasma membrane plasma membrane cell-cell junction cell adhesion external side of plasma membrane external side of plasma membrane cytoplasmic side of plasma membrane cell surface membrane protein kinase binding natural killer cell activation receptor tyrosine kinase binding positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production protein-containing complex heterotypic cell-cell adhesion natural killer cell mediated cytotoxicity identical protein binding identical protein binding protein self-association cell-cell adhesion cell-cell adhesion |
04514 04640 |
| 1450912_at |
Ms4a1 |
membrane-spanning 4-domains, subfamily A, member 1 |
19 |
-11249678 |
BB236617 |
12482 |
50 |
store-operated calcium entry epidermal growth factor receptor binding nucleoplasm plasma membrane plasma membrane cell surface receptor signaling pathway response to bacterium external side of plasma membrane external side of plasma membrane cell surface membrane immunoglobulin binding B cell differentiation B cell activation identical protein binding plasma membrane raft B cell receptor signaling pathway protein tetramerization calcium ion import into cytosol positive regulation of calcium ion import across plasma membrane |
04640 |
| 1419768_at |
Cd22 |
CD22 antigen |
7 |
-30865403, -30865403 |
AF102134 |
12483 |
145 |
negative regulation of immunoglobulin production protein binding early endosome early endosome plasma membrane cell adhesion cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane cell surface coreceptor activity membrane protein phosphatase binding protein phosphatase binding regulation of endocytosis carbohydrate binding regulation of B cell proliferation regulation of B cell proliferation neuronal cell body membrane sialic acid binding sialic acid binding B cell activation B cell activation CD4 receptor binding CD4 receptor binding regulation of immune response negative regulation of calcium-mediated signaling negative regulation of B cell receptor signaling pathway negative regulation of B cell receptor signaling pathway recycling endosome recycling endosome |
04514 04640 04662 |
| 1437025_at |
Cd28 |
CD28 antigen |
1 |
60746387 |
AV313615 |
12487 |
529 |
immunological synapse protease binding positive regulation of inflammatory response to antigenic stimulus plasma membrane transcription by RNA polymerase II immune response external side of plasma membrane external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface positive regulation of gene expression negative regulation of gene expression membrane protein kinase binding T cell costimulation T cell costimulation T cell costimulation T cell costimulation T cell costimulation interleukin-2 production positive regulation of interleukin-10 production positive regulation of interleukin-2 production positive regulation of interleukin-2 production positive regulation of interleukin-4 production CD4-positive, alpha-beta T cell proliferation CD4-positive, alpha-beta T cell proliferation T cell proliferation T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation T cell activation T cell activation regulation of T cell proliferation identical protein binding phosphatidylinositol 3-kinase/protein kinase B signal transduction negative thymic T cell selection regulatory T cell differentiation regulation of regulatory T cell differentiation positive regulation of mitotic nuclear division positive regulation of transcription by RNA polymerase II positive regulation of isotype switching to IgG isotypes T cell receptor signaling pathway T cell receptor signaling pathway positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction apoptotic signaling pathway protein complex involved in cell adhesion positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of CD4-positive, alpha-beta T cell proliferation |
04514 04660 04672 04940 05320 05322 05323 05330 05332 05416 |
| 1450513_at |
Cd33 |
CD33 molecule |
7 |
-43527455 |
NM_021293 |
12489 |
27 |
nucleoplasm peroxisome Golgi apparatus cytosol plasma membrane plasma membrane cell adhesion cell adhesion external side of plasma membrane cell surface membrane protein phosphatase binding carbohydrate binding sialic acid binding sialic acid binding |
04640 |
| 1419206_at |
Cd37 |
CD37 antigen |
7 |
-45233631, -45233631 |
BC019402 |
12493 |
35 |
immunological synapse immunoglobulin production positive regulation of immunoglobulin production regulation of humoral immune response membrane negative regulation of myeloid dendritic cell activation T cell proliferation negative regulation of T cell proliferation defense response to protozoan regulation of defense response to virus |
04640 |
| 1450136_at |
Cd38 |
CD38 antigen |
5 |
43868808 |
NM_007646 |
12494 |
222 |
response to hypoxia NAD+ nucleosidase activity NAD+ nucleosidase activity plasma membrane plasma membrane positive regulation of cytosolic calcium ion concentration positive regulation of cell population proliferation response to xenobiotic stimulus response to hormone cell surface negative regulation of neuron projection development artery smooth muscle contraction membrane basolateral plasma membrane transferase activity hydrolase activity hydrolase activity, acting on glycosyl bonds phosphorus-oxygen lyase activity phosphorus-oxygen lyase activity positive regulation of cell growth positive regulation of B cell proliferation positive regulation of B cell proliferation positive regulation of B cell proliferation positive regulation of insulin secretion response to hydroperoxide B cell proliferation identical protein binding negative regulation of apoptotic process negative regulation of bone resorption negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of vasoconstriction NADP+ nucleosidase activity B cell receptor signaling pathway long-term synaptic depression NAD+ nucleotidase, cyclic ADP-ribose generating |
00760 01100 04020 04640 04970 04972 |
| 1417384_at |
Entpd5 |
ectonucleoside triphosphate diphosphohydrolase 5 |
12 |
-84373875, -84373875 |
NM_007647 |
12499 |
30 |
GDP phosphatase activity GDP phosphatase activity GDP phosphatase activity extracellular region extracellular space endoplasmic reticulum endoplasmic reticulum lumen UDP-glucose metabolic process UDP catabolic process protein N-linked glycosylation nucleoside diphosphate catabolic process membrane hydrolase activity nucleoside diphosphate phosphatase activity ribonucleoside triphosphate phosphatase activity CDP phosphatase activity ADP phosphatase activity UDP phosphatase activity UDP phosphatase activity UDP phosphatase activity 'de novo' post-translational protein folding IDP phosphatase activity |
00230 00240 |
| 1422828_at |
Cd3d |
CD3 antigen, delta polypeptide |
9 |
44981785 |
NM_013487 |
12500 |
58 |
adaptive immune response immune system process transmembrane signaling receptor activity transmembrane signaling receptor activity protein binding plasma membrane cell surface receptor signaling pathway cell surface receptor signaling pathway external side of plasma membrane membrane T cell receptor complex T cell receptor complex alpha-beta T cell receptor complex alpha-beta T cell receptor complex alpha-beta T cell receptor complex T cell activation identical protein binding positive thymic T cell selection positive thymic T cell selection protein-containing complex assembly |
04640 04660 05142 05340 |
| 1422105_at |
Cd3e |
CD3 antigen, epsilon polypeptide |
9 |
-44998742 |
NM_007648 |
12501 |
332 |
immunological synapse positive regulation of cell-matrix adhesion adaptive immune response immune system process positive regulation of T cell anergy T cell anergy transmembrane signaling receptor activity transmembrane signaling receptor activity protein binding endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane cell-cell junction cell surface receptor signaling pathway cell surface receptor signaling pathway smoothened signaling pathway response to nutrient external side of plasma membrane external side of plasma membrane external side of plasma membrane positive regulation of gene expression negative regulation of gene expression membrane dendrite development SH3 domain binding peptidyl-tyrosine phosphorylation calcium-mediated signaling cerebellum development T cell costimulation type II interferon production interleukin-4 production positive regulation of type II interferon production positive regulation of interleukin-2 production positive regulation of interleukin-4 production positive regulation of cell-cell adhesion mediated by integrin CD4-positive, alpha-beta T cell proliferation T cell proliferation T cell receptor complex positive regulation of T cell proliferation positive regulation of T cell proliferation alpha-beta T cell receptor complex alpha-beta T cell receptor complex alpha-beta T cell receptor complex T cell activation identical protein binding dendritic spine cell body positive thymic T cell selection negative thymic T cell selection negative regulation of smoothened signaling pathway lymphocyte activation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling T cell receptor signaling pathway positive regulation of T cell activation apoptotic signaling pathway positive regulation of CD4-positive, alpha-beta T cell proliferation |
04640 04660 05142 05340 |
| 1419178_at |
Cd3g |
CD3 antigen, gamma polypeptide |
9 |
-44969571 |
M58149 |
12502 |
65 |
adaptive immune response immune system process transmembrane signaling receptor activity transmembrane signaling receptor activity cytosol plasma membrane establishment or maintenance of cell polarity cell surface receptor signaling pathway cell surface receptor signaling pathway external side of plasma membrane protein transport membrane alpha-beta T cell receptor complex alpha-beta T cell receptor complex alpha-beta T cell receptor complex identical protein binding positive thymic T cell selection regulation of lymphocyte apoptotic process |
04640 04660 05142 |
| 1426396_at |
Cd247 |
CD247 antigen |
1 |
165788680, 165788680, 165788680 |
AK017904 |
12503 |
174 |
adaptive immune response immune system process transmembrane signaling receptor activity protein binding cytoplasm Golgi apparatus plasma membrane plasma membrane cell surface receptor signaling pathway membrane interleukin-2 production Fc-gamma receptor III complex Fc-gamma receptor signaling pathway T cell receptor complex alpha-beta T cell receptor complex alpha-beta T cell receptor complex alpha-beta T cell receptor complex identical protein binding protein homodimerization activity protein heterodimerization activity T cell receptor signaling pathway T cell receptor signaling pathway protein complex oligomerization protein-containing complex assembly protein tyrosine kinase binding positive regulation of protein localization to cell surface |
04650 04660 05142 |
| 1452483_a_at |
Cd44 |
CD44 antigen |
2 |
-102811141 |
X66083 |
12505 |
648 |
regulation of cell growth branching involved in ureteric bud morphogenesis wound healing involved in inflammatory response positive regulation of adaptive immune response negative regulation of mature B cell apoptotic process transmembrane signaling receptor activity cytokine receptor activity cytokine receptor activity cytokine receptor activity type II transforming growth factor beta receptor binding epidermal growth factor receptor binding protein binding hyaluronic acid binding hyaluronic acid binding hyaluronic acid binding extracellular region Golgi apparatus cytosol plasma membrane plasma membrane plasma membrane microvillus receptor-mediated endocytosis receptor-mediated endocytosis inflammatory response cell adhesion cell adhesion external side of plasma membrane cell surface cell surface positive regulation of gene expression membrane Wnt signaling pathway channel regulator activity basolateral plasma membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane cell migration protein kinase binding cytokine binding hyaluronan catabolic process hyaluronan catabolic process hyaluronan catabolic process neuron projection development lamellipodium membrane protein-containing complex positive regulation of neutrophil apoptotic process positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation positive regulation of heterotypic cell-cell adhesion macrophage fusion macrophage migration inhibitory factor receptor complex macrophage migration inhibitory factor receptor complex macrophage migration inhibitory factor receptor complex cargo receptor activity cargo receptor activity cargo receptor activity T cell activation cell projection negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of DNA damage response, signal transduction by p53 class mediator wound healing, spreading of cells cellular response to fibroblast growth factor stimulus membrane raft negative regulation of regulatory T cell differentiation negative regulation of inflammatory response positive regulation of peptidyl-tyrosine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation phosphoprotein binding branching involved in prostate gland morphogenesis positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade monocyte aggregation positive regulation of monocyte aggregation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator regulation of lamellipodium morphogenesis negative regulation of CD4-positive, alpha-beta T cell proliferation |
04512 04640 |
| 1418353_at |
Cd5 |
CD5 antigen |
19 |
-10718142 |
NM_007650 |
12507 |
144 |
protein binding plasma membrane plasma membrane external side of plasma membrane cell surface membrane T cell costimulation T cell costimulation apoptotic signaling pathway |
04640 |
| 1451910_a_at |
Cd6 |
CD6 antigen |
19 |
-10789338 |
U12434 |
12511 |
36 |
lipopolysaccharide binding immunological synapse formation immunological synapse positive regulation of protein phosphorylation acute inflammatory response to antigenic stimulus protein binding plasma membrane cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules cell surface membrane protein kinase binding lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide T cell receptor complex positive regulation of T cell proliferation identical protein binding lipoteichoic acid binding positive regulation of cytokine production involved in inflammatory response |
04514 |
| 1449164_at |
Cd68 |
CD68 antigen |
11 |
-69664212 |
BC021637 |
12514 |
109 |
inflammatory response to antigenic stimulus negative regulation of dendritic cell antigen processing and presentation lysosome lysosomal membrane lysosomal membrane endosome plasma membrane plasma membrane plasma membrane membrane cellular response to nutrient levels late endosome membrane autocrine signaling cellular response to lipopolysaccharide cellular response to organic substance establishment of protein localization to organelle cellular response to oxidised low-density lipoprotein particle stimulus |
04142 |
| 1428735_at |
Cd69 |
CD69 antigen |
6 |
-129267323 |
AK017979 |
12515 |
117 |
calcium ion binding external side of plasma membrane external side of plasma membrane cell surface membrane carbohydrate binding protein-containing complex identical protein binding cellular response to xenobiotic stimulus |
|
| 1426112_a_at |
Cd72 |
CD72 antigen |
4 |
-43447723 |
BC003824 |
12517 |
70 |
transmembrane signaling receptor activity plasma membrane membrane carbohydrate binding |
04662 |
| 1418830_at |
Cd79a |
CD79A antigen (immunoglobulin-associated alpha) |
7 |
24897496 |
NM_007655 |
12518 |
432 |
adaptive immune response immune system process transmembrane signaling receptor activity protein binding multivesicular body plasma membrane plasma membrane cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane membrane B cell receptor complex B cell receptor complex B cell differentiation B cell differentiation B cell proliferation B cell activation identical protein binding membrane raft B cell receptor signaling pathway B cell receptor signaling pathway IgM B cell receptor complex |
04662 05340 |
| 1416111_at |
Cd83 |
CD83 antigen |
13 |
43785111 |
NM_009856 |
12522 |
66 |
external side of plasma membrane response to organic cyclic compound membrane interleukin-10 production interleukin-2 production interleukin-4 production negative regulation of interleukin-4 production positive regulation of interleukin-10 production positive regulation of interleukin-2 production CD4-positive, alpha-beta T cell differentiation positive regulation of CD4-positive, alpha-beta T cell differentiation |
|
| 1451673_at |
Cd8a |
CD8 subunit alpha |
6 |
71373426 |
M12825 |
12525 |
623 |
adaptive immune response immune system process T cell mediated immunity T cell mediated immunity protein binding plasma membrane plasma membrane cell surface receptor signaling pathway cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface cell surface membrane calcium-mediated signaling protein kinase binding MHC class I protein complex binding T cell activation identical protein binding receptor complex receptor complex plasma membrane raft cytotoxic T cell differentiation cytotoxic T cell differentiation positive regulation of calcium-mediated signaling T cell receptor signaling pathway defense response to virus |
04514 04612 04640 04660 05340 |
| 1426170_a_at |
Cd8b1 |
CD8 subunit beta 1 |
6 |
71322787 |
U34882 |
12526 |
115 |
adaptive immune response immune system process protein binding plasma membrane plasma membrane external side of plasma membrane cell surface cell surface coreceptor activity membrane MHC class I protein binding receptor complex regulation of immune response |
04514 04612 04640 04660 05340 |
| 1426002_a_at |
Cdc7 |
cell division cycle 7 |
5 |
106964321, 106964560 |
AB018574 |
12545 |
39 |
nucleotide binding double-strand break repair via break-induced replication protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm protein phosphorylation cell cycle signal transduction positive regulation of cell population proliferation positive regulation of nuclear cell cycle DNA replication positive regulation of G2/M transition of mitotic cell cycle kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation cell cycle phase transition intercellular bridge metal ion binding cell division mitotic spindle |
04110 |
| 1424638_at |
Cdkn1a |
cyclin dependent kinase inhibitor 1A |
17 |
29090978, 29093768 |
AK007630 |
12575 |
1178 |
regulation of cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein kinase holoenzyme complex cyclin-dependent protein kinase holoenzyme complex cyclin-dependent protein kinase holoenzyme complex in utero embryonic development protein kinase inhibitor activity protein kinase inhibitor activity cyclin-dependent protein serine/threonine kinase inhibitor activity protein binding nucleus nucleus nucleus nucleoplasm nucleolus cytoplasm cytosol protein import into nucleus DNA damage response DNA damage response DNA damage response DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle mitotic G2 DNA damage checkpoint signaling regulation of mitotic cell cycle regulation of mitotic cell cycle heart development negative regulation of cell population proliferation negative regulation of cell population proliferation epidermis development response to UV regulation of G2/M transition of mitotic cell cycle negative regulation of gene expression nuclear body protein kinase binding cyclin-dependent protein kinase activating kinase activity keratinocyte differentiation negative regulation of cell growth cyclin binding positive regulation of B cell proliferation ubiquitin protein ligase binding cellular response to extracellular stimulus negative regulation of protein binding protein-containing complex cellular response to amino acid starvation cellular response to amino acid starvation wound healing tissue regeneration negative regulation of phosphorylation intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of apoptotic process positive regulation of programmed cell death keratinocyte proliferation protein-containing complex binding negative regulation of cyclin-dependent protein serine/threonine kinase activity negative regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of protein kinase activity metal ion binding fibroblast proliferation positive regulation of fibroblast proliferation perinuclear region of cytoplasm regulation of cell cycle regulation of cell cycle regulation of cell cycle PCNA-p21 complex cellular response to ionizing radiation cellular response to gamma radiation cellular response to UV-B signal transduction by p53 class mediator cellular senescence cellular senescence oncogene-induced cell senescence oncogene-induced cell senescence protein sequestering activity molecular function activator activity molecular function inhibitor activity regulation of cell cycle G1/S phase transition negative regulation of cyclin-dependent protein kinase activity negative regulation of vascular associated smooth muscle cell proliferation negative regulation of cardiac muscle tissue regeneration regulation of G1/S transition of mitotic cell cycle regulation of G1/S transition of mitotic cell cycle negative regulation of G1/S transition of mitotic cell cycle regulation of DNA biosynthetic process negative regulation of DNA biosynthetic process positive regulation of reactive oxygen species metabolic process |
04012 04110 04115 05160 05200 05214 05215 05218 05219 05220 |
| 1420497_a_at |
Cebpz |
CCAAT/enhancer binding protein zeta |
17 |
-78919002 |
NM_009882 |
12607 |
25 |
transcription coactivator activity nucleus nucleus CCAAT-binding factor complex positive regulation of transcription by RNA polymerase II |
|
| 1427844_a_at |
Cebpb |
CCAAT/enhancer binding protein beta |
2 |
167688914 |
AB012278 |
12608 |
583 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II condensed chromosome, centromeric region chromatin transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific ovarian follicle development embryonic placenta development granuloma formation DNA binding DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II positive regulation of gene expression nuclear matrix nuclear matrix kinase binding cell differentiation neuron differentiation chromatin DNA binding response to lipopolysaccharide regulation of interleukin-6 production positive regulation of interleukin-4 production mammary gland epithelial cell proliferation response to endoplasmic reticulum stress histone acetyltransferase binding nuclear glucocorticoid receptor binding T-helper 1 cell activation CHOP-C/EBP complex negative regulation of T cell proliferation defense response to bacterium identical protein binding protein homodimerization activity histone deacetylase binding negative regulation of neuron apoptotic process sequence-specific DNA binding sequence-specific DNA binding ubiquitin-like protein ligase binding fat cell differentiation fat cell differentiation regulation of cell differentiation positive regulation of fat cell differentiation positive regulation of osteoblast differentiation regulation of osteoclast differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein heterodimerization activity positive regulation of inflammatory response brown fat cell differentiation mammary gland epithelial cell differentiation myeloid cell development RNA polymerase II-specific DNA-binding transcription factor binding intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress positive regulation of biomineral tissue development cellular response to lipopolysaccharide cellular response to amino acid stimulus cellular response to interleukin-1 hepatocyte proliferation hepatocyte proliferation RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex liver regeneration positive regulation of cold-induced thermogenesis DNA-binding transcription factor binding regulation of odontoblast differentiation regulation of odontoblast differentiation C/EBP complex C/EBP complex sequence-specific double-stranded DNA binding positive regulation of sodium-dependent phosphate transport regulation of dendritic cell differentiation |
|
| 1418066_at |
Cfl2 |
cofilin 2, muscle |
12 |
-54858818 |
AI323758 |
12632 |
51 |
actin binding nucleus cytoplasm cytoplasm cytoskeleton actin filament organization skeletal muscle tissue development actin cytoskeleton actin cytoskeleton Z disc actin filament depolymerization actin filament depolymerization actin filament depolymerization actin filament fragmentation actin filament fragmentation positive regulation of actin filament depolymerization I band sarcomere organization muscle cell cellular homeostasis actin filament severing actin filament binding actin filament binding |
04360 04666 04810 |
| 1451537_at |
Chi3l1 |
chitinase 3 like 1 |
1 |
134182403, 134182155 |
BC005611 |
12654 |
98 |
protein binding extracellular region extracellular region extracellular space cytoplasm endoplasmic reticulum carbohydrate metabolic process chitin catabolic process apoptotic process inflammatory response activation of NF-kappaB-inducing kinase activity chitin binding chitin binding positive regulation of peptidyl-threonine phosphorylation lung development positive regulation of interleukin-8 production positive regulation of angiogenesis positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of ERK1 and ERK2 cascade |
00520 |
| 1419764_at |
Chil3 |
chitinase-like 3 |
3 |
-106147553 |
NM_009892 |
12655 |
67 |
polysaccharide catabolic process production of molecular mediator involved in inflammatory response beta-N-acetylhexosaminidase activity extracellular region extracellular region extracellular space nucleus cytoplasm endoplasmic reticulum carbohydrate metabolic process chitin catabolic process chitin catabolic process inflammatory response chitin binding chitin binding metabolic process hydrolase activity hydrolase activity, acting on glycosyl bonds kinase binding carbohydrate binding cytoplasmic vesicle positive regulation of chemokine production N-acetyl-beta-D-galactosaminidase activity |
|
| 1416332_at |
Cirbp |
cold inducible RNA binding protein |
10 |
80167838, 80167838, 80167838, 80168170, 80165989 |
NM_007705 |
12696 |
87 |
nucleic acid binding RNA binding RNA binding mRNA 3'-UTR binding nucleus nucleus nucleoplasm nucleoplasm spliceosomal complex cytoplasm cytoplasm poly(U) RNA binding response to UV cytoplasmic stress granule negative regulation of cell growth translation repressor activity stress granule assembly positive regulation of translation positive regulation of mRNA splicing, via spliceosome mRNA stabilization small ribosomal subunit rRNA binding cellular response to cold regulation of cell cycle G1/S phase transition |
|
| 1455899_x_at |
Socs3 |
suppressor of cytokine signaling 3 |
11 |
-117966086 |
BB241535 |
12702 |
471 |
phosphotyrosine residue binding regulation of protein phosphorylation protein binding cytosol phosphatidylinositol 3-kinase complex signal transduction receptor signaling pathway via JAK-STAT cytoplasmic side of plasma membrane negative regulation of signal transduction cell differentiation cell differentiation protein tyrosine kinase inhibitor activity miRNA binding miRNA binding intracellular signal transduction negative regulation of tyrosine phosphorylation of STAT protein positive regulation of cell differentiation positive regulation of cell differentiation negative regulation of receptor signaling pathway via JAK-STAT negative regulation of insulin receptor signaling pathway phosphatidylinositol phosphate biosynthetic process 1-phosphatidylinositol-3-kinase regulator activity negative regulation of inflammatory response branching involved in labyrinthine layer morphogenesis placenta blood vessel development cellular response to interleukin-17 cellular response to leukemia inhibitory factor |
04120 04380 04630 04910 04920 04930 05160 |
| 1450446_a_at |
Socs1 |
suppressor of cytokine signaling 1 |
16 |
-10783808 |
AB000710 |
12703 |
327 |
regulation of cytokine production regulation of protein phosphorylation insulin-like growth factor receptor binding protein binding nucleus nucleoplasm cytosol phosphatidylinositol 3-kinase complex receptor signaling pathway via JAK-STAT negative regulation of signal transduction regulation of activation of Janus kinase activity kinase inhibitor activity cytokine-mediated signaling pathway cytokine-mediated signaling pathway protein kinase binding macrophage differentiation cytoplasmic vesicle intracellular signal transduction cytoplasmic ribonucleoprotein granule regulation of tyrosine phosphorylation of STAT protein negative regulation of tyrosine phosphorylation of STAT protein negative regulation of tyrosine phosphorylation of STAT protein positive regulation of CD4-positive, alpha-beta T cell differentiation negative regulation of CD8-positive, alpha-beta T cell differentiation fat cell differentiation positive regulation of regulatory T cell differentiation regulation of receptor signaling pathway via JAK-STAT negative regulation of receptor signaling pathway via JAK-STAT negative regulation of receptor signaling pathway via JAK-STAT negative regulation of insulin receptor signaling pathway phosphatidylinositol phosphate biosynthetic process 1-phosphatidylinositol-3-kinase regulator activity cellular response to amino acid stimulus cellular response to cytokine stimulus cellular response to organic cyclic compound negative regulation of hepatic stellate cell proliferation positive regulation of fibroblast apoptotic process |
04120 04380 04630 04910 04930 05145 |
| 1426124_a_at |
Clk1 |
CDC-like kinase 1 |
1 |
-58411987 |
U21209 |
12747 |
43 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein tyrosine kinase activity protein binding ATP binding nucleus nucleus protein phosphorylation kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation peptidyl-tyrosine phosphorylation peptidyl-tyrosine phosphorylation regulation of RNA splicing regulation of RNA splicing protein autophosphorylation |
|
| 1417743_at |
Clk2 |
CDC-like kinase 2 |
3 |
89164794 |
BC015080 |
12748 |
35 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein tyrosine kinase activity ATP binding nucleus nucleus nucleus nucleoplasm protein phosphorylation protein phosphorylation response to organic substance response to ionizing radiation kinase activity phosphorylation nuclear body transferase activity peptidyl-tyrosine phosphorylation peptidyl-tyrosine phosphorylation response to retinoic acid identical protein binding regulation of RNA splicing regulation of RNA splicing negative regulation of gluconeogenesis protein autophosphorylation |
|
| 1422886_a_at |
Clk4 |
CDC like kinase 4 |
11 |
51263113 |
NM_007714 |
12750 |
24 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein tyrosine kinase activity ATP binding nucleus nucleus protein phosphorylation kinase activity phosphorylation transferase activity peptidyl-tyrosine phosphorylation peptidyl-tyrosine phosphorylation regulation of RNA splicing regulation of RNA splicing protein autophosphorylation |
|
| 1421734_at |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
1 |
74153993 |
NM_009909 |
12765 |
350 |
acute inflammatory response to antigenic stimulus positive regulation of leukocyte chemotaxis interleukin-8 receptor activity interleukin-8 receptor activity G protein-coupled receptor activity chemokine receptor activity chemokine receptor activity protein binding nucleoplasm plasma membrane chemotaxis chemotaxis immune response cellular defense response signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration positive regulation of cell population proliferation external side of plasma membrane cell surface positive regulation of cardiac muscle cell apoptotic process microtubule cytoskeleton membrane C-C chemokine receptor activity C-X-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding interleukin-8 binding neutrophil chemotaxis neutrophil chemotaxis receptor internalization negative regulation of neutrophil apoptotic process interleukin-8-mediated signaling pathway neutrophil activation mast cell granule negative regulation of apoptotic process negative regulation of apoptotic process positive regulation of vascular permeability positive regulation of angiogenesis metanephric tubule morphogenesis mitotic spindle positive regulation of neutrophil chemotaxis |
04060 04062 04144 |
| 1449925_at |
Cxcr3 |
C-X-C motif chemokine receptor 3 |
X |
-101731534 |
NM_009910 |
12766 |
339 |
angiogenesis negative regulation of endothelial cell proliferation regulation of leukocyte migration G protein-coupled receptor activity chemokine receptor activity plasma membrane chemotaxis inflammatory response immune response signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration positive regulation of cell population proliferation external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface cell surface T cell chemotaxis membrane C-C chemokine receptor activity C-X-C chemokine receptor activity negative regulation of angiogenesis calcium-mediated signaling calcium-mediated signaling chemokine binding C-C chemokine binding C-X-C chemokine binding regulation of cell adhesion signaling receptor activity positive regulation of angiogenesis positive regulation of transcription by RNA polymerase II positive regulation of chemotaxis positive regulation of release of sequestered calcium ion into cytosol cell chemotaxis negative regulation of execution phase of apoptosis positive regulation of execution phase of apoptosis |
04060 04062 |
| 1448710_at |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
1 |
-128588198 |
D87747 |
12767 |
672 |
branching involved in blood vessel morphogenesis neuron migration neuron migration kidney development positive regulation of protein phosphorylation epithelial cell development ventricular septum development actin binding G protein-coupled receptor activity chemokine receptor activity protein binding lysosome endosome early endosome late endosome plasma membrane plasma membrane cell-cell junction chemotaxis immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration germ cell development nervous system development brain development brain development motor neuron axon guidance germ cell migration animal organ morphogenesis external side of plasma membrane external side of plasma membrane cell surface cell surface response to organic cyclic compound membrane cell migration C-C chemokine receptor activity calcium-mediated signaling calcium-mediated signaling cytokine binding C-C chemokine binding C-C chemokine binding neurogenesis neurogenesis telencephalon cell migration regulation of cell adhesion regulation of cell migration regulation of cell migration positive regulation of cell migration growth cone cell leading edge cytoplasmic vesicle ubiquitin protein ligase binding myosin light chain binding protein-containing complex positive regulation of vascular wound healing hematopoietic stem cell migration aorta development small molecule binding C-X-C motif chemokine 12 receptor activity CXCL12-activated CXCR4 signaling pathway CXCL12-activated CXCR4 signaling pathway T cell proliferation regulation of programmed cell death ubiquitin binding myelin maintenance blood vessel endothelial cell migration endothelial cell differentiation generation of neurons positive regulation of oligodendrocyte differentiation positive regulation of neurogenesis regulation of viral process regulation of chemotaxis positive regulation of chemotaxis detection of temperature stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of pain regulation of calcium ion transport cardiac muscle contraction cell chemotaxis endothelial tube morphogenesis neural precursor cell proliferation anchoring junction positive regulation of ERK1 and ERK2 cascade cellular response to cytokine stimulus cellular response to cytokine stimulus cellular response to organonitrogen compound positive regulation of calcium ion import positive regulation of cold-induced thermogenesis response to tacrolimus positive regulation of dendrite extension positive regulation of vasculature development positive regulation of mesenchymal stem cell migration positive regulation of macrophage migration inhibitory factor signaling pathway regulation of neuron migration |
04060 04062 04144 04360 04670 04672 |
| 1419609_at |
Ccr1 |
C-C motif chemokine receptor 1 |
9 |
-123962125 |
AV231648 |
12768 |
160 |
phosphatidylinositol phospholipase C activity G protein-coupled receptor activity chemokine receptor activity protein binding cytoplasm plasma membrane calcium ion transport intracellular calcium ion homeostasis exocytosis chemotaxis inflammatory response inflammatory response immune response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration cell-cell signaling external side of plasma membrane external side of plasma membrane negative regulation of gene expression membrane C-C chemokine receptor activity C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding myeloid cell differentiation positive regulation of cell migration negative regulation of bone mineralization leukocyte chemotaxis leukocyte chemotaxis chemokine (C-C motif) ligand 7 binding chemokine (C-C motif) ligand 7 binding neuronal cell body positive regulation of osteoclast differentiation negative regulation of innate immune response positive regulation of calcium ion transport cell chemotaxis chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade chemokine (C-C motif) ligand 5 binding chemokine (C-C motif) ligand 5 binding positive regulation of monocyte chemotaxis |
04060 04062 |
| 1427419_x_at |
Ccr9 |
C-C motif chemokine receptor 9 |
9 |
123767210 |
AJ131357 |
12769 |
95 |
CD8-positive, gamma-delta intraepithelial T cell differentiation G protein-coupled receptor activity chemokine receptor activity protein binding plasma membrane chemotaxis immune response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration external side of plasma membrane cell surface membrane C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding cell chemotaxis |
04060 04062 04672 |
| 1424727_at |
Ccr5 |
C-C motif chemokine receptor 5 |
9 |
124121542 |
D83648 |
12774 |
379 |
actin binding G protein-coupled receptor activity chemokine receptor activity cytoplasm endosome plasma membrane calcium ion transport chemotaxis defense response inflammatory response inflammatory response immune response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration cell-cell signaling external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface cell surface positive regulation of gene expression release of sequestered calcium ion into cytosol by sarcoplasmic reticulum membrane C-C chemokine receptor activity C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling calcium-mediated signaling protein kinase binding C-C chemokine binding C-C chemokine binding positive regulation of cell-cell adhesion regulation of cell migration negative regulation of axon extension positive regulation of cell killing positive regulation of fever generation positive regulation of interleukin-1 beta production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production identical protein binding positive regulation of neuron differentiation cell chemotaxis response to cholesterol chemokine (C-C motif) ligand 5 binding chemokine (C-C motif) ligand 5 binding negative regulation of macrophage apoptotic process negative regulation of neural precursor cell proliferation |
04060 04062 04144 05145 |
| 1423466_at |
Ccr7 |
C-C motif chemokine receptor 7 |
11 |
-99144198 |
BB204380 |
12775 |
392 |
establishment of T cell polarity myeloid dendritic cell chemotaxis lymphocyte chemotaxis across high endothelial venule positive regulation of dendritic cell antigen processing and presentation regulation of tolerance induction to self antigen positive regulation of hypersensitivity positive regulation of humoral immune response G protein-coupled receptor activity chemokine receptor activity protein binding mitochondrion plasma membrane plasma membrane chemotaxis inflammatory response inflammatory response immune response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration external side of plasma membrane external side of plasma membrane cell surface cell surface positive regulation of macrophage chemotaxis positive regulation of T cell chemotaxis membrane C-C chemokine receptor activity calcium-mediated signaling actin cytoskeleton organization response to lipopolysaccharide regulation of type II interferon production regulation of interleukin-1 beta production negative regulation of interleukin-12 production positive regulation of interleukin-1 beta production positive regulation of interleukin-12 production positive regulation of tumor necrosis factor production response to prostaglandin E chemokine (C-C motif) ligand 19 binding chemokine (C-C motif) ligand 19 binding chemokine (C-C motif) ligand 21 binding chemokine (C-C motif) ligand 21 binding C-C motif chemokine 19 receptor activity C-C motif chemokine 19 receptor activity C-C motif chemokine 21 receptor activity positive regulation of T cell proliferation positive regulation of JUN kinase activity positive regulation of GTPase activity negative thymic T cell selection positive regulation of T-helper 1 cell differentiation positive regulation of receptor-mediated endocytosis lymph node development homeostasis of number of cells positive regulation of phagocytosis positive regulation of T cell receptor signaling pathway positive regulation of filopodium assembly cell chemotaxis cellular response to cytokine stimulus response to nitric oxide positive regulation of neutrophil chemotaxis positive regulation of neutrophil chemotaxis lymphocyte migration into lymph node mature conventional dendritic cell differentiation negative regulation of leukocyte apoptotic process positive regulation of cell motility positive regulation of thymocyte migration positive regulation of dendritic cell chemotaxis positive regulation of immunological synapse formation positive regulation of T cell costimulation positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation regulation of dendritic cell dendrite assembly |
04060 04062 |
| 1419691_at |
Camp |
cathelicidin antimicrobial peptide |
9 |
-109847376 |
NM_009921 |
12796 |
135 |
lipopolysaccharide binding response to yeast positive regulation of protein phosphorylation innate immune response in mucosa immune system process chronic inflammatory response extracellular region extracellular space extracellular space defense response positive regulation of cell population proliferation antibacterial humoral response antifungal humoral response cytolysis positive regulation of interleukin-8 production modulation of process of another organism neutrophil activation specific granule specific granule defense response to bacterium defense response to bacterium cell projection innate immune response innate immune response innate immune response positive regulation of angiogenesis defense response to Gram-negative bacterium defense response to Gram-negative bacterium defense response to Gram-negative bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium cytolysis by host of symbiont cells killing by host of symbiont cells killing by host of symbiont cells antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide amyloid fibril formation |
04970 |
| 1416740_at |
Col5a1 |
collagen, type V, alpha 1 |
2 |
27886424 |
AW744319 |
12831 |
97 |
blood vessel development heart morphogenesis extracellular matrix structural constituent protein binding extracellular region collagen trimer collagen trimer collagen type V trimer collagen type V trimer collagen type XI trimer basement membrane extracellular space extracellular space cell adhesion cell adhesion heparin binding heparin binding cell migration extracellular matrix structural constituent conferring tensile strength extracellular matrix structural constituent conferring tensile strength collagen fibril organization collagen fibril organization collagen fibril organization collagen fibril organization extracellular matrix collagen biosynthetic process wound healing, spreading of epidermal cells tendon development tendon development proteoglycan binding skin development skin development integrin biosynthetic process platelet-derived growth factor binding eye morphogenesis regulation of cellular component organization collagen-containing extracellular matrix collagen-containing extracellular matrix collagen-containing extracellular matrix collagen-containing extracellular matrix supramolecular fiber organization negative regulation of endodermal cell differentiation |
04510 04512 04974 05146 |
| 1459885_s_at |
Cox7c |
cytochrome c oxidase subunit 7C |
13 |
-86044797 |
AA190297 |
12867 |
32 |
protein binding mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex IV mitochondrial respiratory chain complex IV mitochondrial electron transport, cytochrome c to oxygen mitochondrial electron transport, cytochrome c to oxygen membrane mitochondrial membrane |
00190 01100 04260 05010 05012 05016 |
| 1455393_at |
Cp |
ceruloplasmin |
3 |
19957053, 19957053, 19957053, 19957248 |
BB009037 |
12870 |
105 |
ferroxidase activity ferroxidase activity glutathione peroxidase activity copper ion binding copper ion binding extracellular region extracellular space extracellular space extracellular space plasma membrane monoatomic ion transport copper ion transport iron ion transport intracellular copper ion homeostasis intracellular iron ion homeostasis cell surface oxidoreductase activity oxidoreductase activity oxidoreductase activity, acting on metal ions, oxygen as acceptor response to copper ion metal ion binding phospholipid-hydroperoxide glutathione peroxidase activity protein-folding chaperone binding |
00860 |
| 1448730_at |
Cpa3 |
carboxypeptidase A3, mast cell |
3 |
-20215615 |
NM_007753 |
12873 |
65 |
regulation of angiotensin levels in blood carboxypeptidase activity metallocarboxypeptidase activity metallocarboxypeptidase activity extracellular space proteolysis proteolysis peptidase activity metallopeptidase activity zinc ion binding hydrolase activity cytoplasmic vesicle metal ion binding |
04614 04972 04974 |
| 1455009_at |
Cpd |
carboxypeptidase D |
11 |
-76777207 |
AW550842 |
12874 |
24 |
carboxypeptidase activity metallocarboxypeptidase activity metallocarboxypeptidase activity extracellular space nucleus trans-Golgi network plasma membrane proteolysis peptide metabolic process peptidase activity metallopeptidase activity zinc ion binding membrane protein processing hydrolase activity protein-containing complex binding metal ion binding perinuclear region of cytoplasm protein phosphatase 2A binding |
|
| 1425289_a_at |
Cr2 |
complement receptor 2 |
1 |
-195136811 |
M35684 |
12902 |
184 |
complement binding immune system process T cell mediated immunity DNA binding complement receptor activity protein binding extracellular space extracellular space plasma membrane plasma membrane inflammatory response complement activation, alternative pathway complement activation, alternative pathway complement activation, classical pathway external side of plasma membrane cell surface membrane immunoglobulin mediated immune response B cell differentiation immunoglobulin receptor binding signaling receptor activity B cell proliferation protein homodimerization activity receptor complex innate immune response negative regulation of complement activation, classical pathway cartilage development bone development cellular response to lipopolysaccharide |
04610 04640 04662 |
| 1449037_at |
Crem |
cAMP responsive element modulator |
18 |
-3294165, -3266353, -3266353, -3266353, -3266353, -3266353 |
AI467599 |
12916 |
157 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus transcription regulator complex cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II glycosphingolipid metabolic process spermatogenesis spermatogenesis circadian rhythm circadian regulation of gene expression negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II rhythmic process response to cAMP ATF4-CREB1 transcription factor complex sequence-specific double-stranded DNA binding |
|
| 1416326_at |
Crip1 |
cysteine-rich protein 1 |
12 |
113152011 |
NM_007763 |
12925 |
34 |
cytoplasm cytoplasm zinc ion binding zinc ion binding zinc ion binding intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage response to zinc ion response to zinc ion regulation of gene expression peptide binding peptide binding metal ion binding cellular response to antibiotic cellular response to antibiotic cellular response to UV-B cellular response to UV-B |
|
| 1421946_at |
Crp |
C-reactive protein, pentraxin-related |
1 |
172698055 |
NM_007768 |
12944 |
92 |
complement component C1q complex binding complement component C1q complex binding calcium ion binding extracellular region extracellular space extracellular space acute-phase response complement activation, classical pathway positive regulation of gene expression negative regulation of macrophage derived foam cell differentiation negative regulation of lipid storage regulation of low-density lipoprotein particle clearance cholesterol binding low-density lipoprotein particle binding low-density lipoprotein particle binding filopodium growth cone regulation of interleukin-8 production negative regulation of superoxide anion generation positive regulation of superoxide anion generation negative regulation of mononuclear cell proliferation vasoconstriction identical protein binding innate immune response positive regulation of nitric oxide biosynthetic process metal ion binding low-density lipoprotein particle receptor binding protein polymerization cellular response to calcium ion positive regulation of dendrite development |
|
| 1420703_at |
Csf2ra |
colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
19 |
-61224401 |
BM941868 |
12982 |
48 |
cytokine receptor activity receptor signaling pathway via JAK-STAT membrane granulocyte macrophage colony-stimulating factor receptor complex granulocyte-macrophage colony-stimulating factor signaling pathway positive regulation of leukocyte proliferation |
04060 04630 04640 05200 |
| 1455660_at |
Csf2rb |
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
15 |
78325799, 78325989 |
BB769628 |
12983 |
153 |
regulation of cell growth cytokine receptor activity cytokine receptor activity protein binding plasma membrane receptor signaling pathway via JAK-STAT external side of plasma membrane coreceptor activity membrane immunoglobulin mediated immune response cytokine-mediated signaling pathway cytokine-mediated signaling pathway granulocyte macrophage colony-stimulating factor receptor complex interleukin-5-mediated signaling pathway interleukin-3-mediated signaling pathway granulocyte-macrophage colony-stimulating factor signaling pathway positive regulation of leukocyte proliferation |
04060 04210 04630 |
| 1449360_at |
Csf2rb2 |
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) |
15 |
-78282507 |
NM_007781 |
12984 |
59 |
cytokine receptor activity cytokine receptor activity plasma membrane plasma membrane receptor signaling pathway via JAK-STAT external side of plasma membrane coreceptor activity membrane immunoglobulin mediated immune response cytokine-mediated signaling pathway cytokine-mediated signaling pathway granulocyte macrophage colony-stimulating factor receptor complex interleukin-5-mediated signaling pathway interleukin-3-mediated signaling pathway granulocyte-macrophage colony-stimulating factor signaling pathway positive regulation of leukocyte proliferation |
04060 04210 04630 |
| 1427256_at |
Vcan |
versican |
13 |
-89655309, -89709947 |
BM251152 |
13003 |
224 |
skeletal system development ureteric bud development positive regulation of neuroblast proliferation calcium ion binding hyaluronic acid binding extracellular region extracellular space cell adhesion central nervous system development heart development glial cell migration cell surface glial cell differentiation protein phosphatase binding extracellular matrix structural constituent conferring compression resistance carbohydrate binding extracellular matrix cell projection regulation of phosphoprotein phosphatase activity synapse synapse collagen-containing extracellular matrix collagen-containing extracellular matrix perineuronal net perineuronal net |
04514 |
| 1422506_a_at |
Cstb |
cystatin B |
10 |
78425669 |
NM_007793 |
13014 |
60 |
protease binding endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity extracellular space nucleus nucleolus cytoplasm cytosol cytosol adult locomotory behavior negative regulation of peptidase activity peptidase inhibitor activity negative regulation of proteolysis collagen-containing extracellular matrix |
|
| 1434705_at |
Ctbp2 |
C-terminal binding protein 2 |
7 |
-132987010, -132987010, -132987010 |
BG072903 |
13017 |
152 |
transcription coregulator binding transcription coregulator binding transcription corepressor binding chromatin binding transcription coactivator activity transcription coactivator activity transcription corepressor activity transcription corepressor activity transcription corepressor activity protein binding nucleus nucleus nucleus cytosol regulation of transcription by RNA polymerase II synaptic vesicle docking synaptic vesicle docking oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor transcription repressor complex protein kinase binding cell differentiation positive regulation of chromatin binding identical protein binding nuclear retinoic acid receptor binding protein-containing complex binding synapse negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of retinoic acid receptor signaling pathway positive regulation of retinoic acid receptor signaling pathway white fat cell differentiation NAD binding ribbon synapse photoreceptor ribbon synapse photoreceptor ribbon synapse photoreceptor ribbon synapse presynaptic active zone cytoplasmic component structural constituent of presynaptic active zone structural constituent of presynaptic active zone glutamatergic synapse glutamatergic synapse GABA-ergic synapse presynaptic cytosol DNA-binding transcription factor binding cellular response to leukemia inhibitory factor |
04310 04330 05200 05220 |
| 1416382_at |
Ctsc |
cathepsin C |
7 |
88278084, 88278084 |
NM_009982 |
13032 |
79 |
T cell mediated cytotoxicity cysteine-type endopeptidase activity serine-type endopeptidase activity extracellular space nucleoplasm cytoplasm lysosome lysosome centrosome proteolysis proteolysis peptidase activity cysteine-type peptidase activity cysteine-type peptidase activity dipeptidyl-peptidase activity response to organic substance peptidase activator activity involved in apoptotic process hydrolase activity phosphatase binding chloride ion binding negative regulation of myelination negative regulation of myelination identical protein binding intracellular membrane-bounded organelle protein self-association protein-folding chaperone binding proteolysis involved in protein catabolic process collagen-containing extracellular matrix positive regulation of proteolysis involved in protein catabolic process positive regulation of microglial cell activation positive regulation of apoptotic signaling pathway |
04142 |
| 1451310_a_at |
Ctsl |
cathepsin L |
13 |
-64361889 |
J02583 |
13039 |
221 |
fibronectin binding endopeptidase activity aminopeptidase activity cysteine-type endopeptidase activity cysteine-type endopeptidase activity protein binding collagen binding extracellular region extracellular space extracellular space extracellular space nucleus nucleolus lysosome lysosome lysosome multivesicular body Golgi apparatus plasma membrane microvillus proteolysis proteolysis thyroid hormone generation immune response peptidase activity cysteine-type peptidase activity cysteine-type endopeptidase activator activity involved in apoptotic process external side of plasma membrane external side of plasma membrane negative regulation of keratinocyte proliferation positive regulation of peptidase activity membrane hydrolase activity cysteine-type carboxypeptidase activity secretory granule protein catabolic process collagen catabolic process kininogen binding hair follicle morphogenesis cytoplasmic vesicle peptide binding histone binding histone binding catagen perikaryon intracellular membrane-bounded organelle CD4-positive, alpha-beta T cell lineage commitment proteoglycan binding keratinocyte proliferation protein-containing complex binding apical part of cell decidualization antigen processing and presentation of peptide antigen proteolysis involved in protein catabolic process proteolysis involved in protein catabolic process elastin catabolic process collagen-containing extracellular matrix serpin family protein binding positive regulation of apoptotic signaling pathway |
04142 04145 04612 05323 |
| 1454268_a_at |
Cyba |
cytochrome b-245, alpha polypeptide |
8 |
-122424770 |
AK018713 |
13057 |
75 |
stress fiber positive regulation of endothelial cell proliferation negative regulation of glomerular filtration by angiotensin protein binding cytoplasm mitochondrion endosome plasma membrane focal adhesion superoxide metabolic process inflammatory response electron transfer activity smooth muscle hypertrophy membrane superoxide-generating NAD(P)H oxidase activity apical plasma membrane oxidoreductase activity cytochrome complex assembly SH3 domain binding heme binding positive regulation of cell growth dendrite positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of superoxide anion generation positive regulation of toll-like receptor 2 signaling pathway superoxide anion generation superoxide anion generation NADPH oxidase complex NADPH oxidase complex NADPH oxidase complex neuronal cell body innate immune response innate immune response respiratory burst positive regulation of blood pressure metal ion binding protein heterodimerization activity positive regulation of smooth muscle cell proliferation hydrogen peroxide biosynthetic process positive regulation of phagocytosis regulation of release of sequestered calcium ion into cytosol establishment of localization in cell mucus secretion positive regulation of mucus secretion cellular response to organic substance reactive oxygen species metabolic process perinuclear endoplasmic reticulum positive regulation of defense response to bacterium positive regulation of reactive oxygen species biosynthetic process |
04145 04380 04670 05140 |
| 1422978_at |
Cybb |
cytochrome b-245, beta polypeptide |
X |
-9435253 |
NM_007807 |
13058 |
775 |
protein binding nuclear envelope cytoplasm mitochondrion plasma membrane plasma membrane plasma membrane superoxide metabolic process superoxide metabolic process monoatomic ion transport defense response inflammatory response electron transfer activity response to xenobiotic stimulus membrane superoxide-generating NAD(P)H oxidase activity superoxide-generating NAD(P)H oxidase activity superoxide-generating NAD(P)H oxidase activity oxidoreductase activity heme binding dendrite positive regulation of tumor necrosis factor production monoatomic ion transmembrane transport monoatomic ion channel complex superoxide anion generation superoxide anion generation NADPH oxidase complex NADPH oxidase complex NADPH oxidase complex neuronal cell body innate immune response innate immune response phagocytic vesicle respiratory burst positive regulation of angiogenesis metal ion binding protein heterodimerization activity flavin adenine dinucleotide binding hydrogen peroxide biosynthetic process perinuclear endoplasmic reticulum hypoxia-inducible factor-1alpha signaling pathway |
04145 04380 04670 |
| 1425645_s_at |
Cyp2b10 |
cytochrome P450, family 2, subfamily b, polypeptide 10 |
7 |
25897657 |
AF128849 |
13088 |
63 |
monooxygenase activity iron ion binding cytoplasm mitochondrial inner membrane endoplasmic reticulum xenobiotic metabolic process xenobiotic metabolic process steroid metabolic process testosterone 16-alpha-hydroxylase activity arachidonic acid epoxygenase activity steroid hydroxylase activity response to bacterium membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen epoxygenase P450 pathway heme binding heme binding Hsp70 protein binding xenobiotic catabolic process cellular ketone metabolic process intracellular membrane-bounded organelle intracellular membrane-bounded organelle metal ion binding Hsp90 protein binding testosterone 16-beta-hydroxylase activity anandamide 8,9 epoxidase activity anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity aromatase activity estrogen 2-hydroxylase activity |
00590 00830 00980 00982 01100 |
| 1415994_at |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
7 |
140763818 |
NM_021282 |
13106 |
179 |
Golgi membrane long-chain fatty acid metabolic process lipid hydroxylation monooxygenase activity monooxygenase activity iron ion binding cytoplasm mitochondrion mitochondrial inner membrane endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process fatty acid metabolic process triglyceride metabolic process xenobiotic metabolic process xenobiotic metabolic process steroid metabolic process arachidonic acid epoxygenase activity response to bacterium membrane monoterpenoid metabolic process oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 4-nitrophenol 2-monooxygenase activity 4-nitrophenol metabolic process epoxygenase P450 pathway enzyme binding heme binding heme binding Hsp70 protein binding intracellular membrane-bounded organelle intracellular membrane-bounded organelle heterocycle metabolic process metal ion binding Hsp90 protein binding aromatase activity long-chain fatty acid omega-1 hydroxylase activity |
00590 00591 00980 00982 01100 |
| 1416809_at |
Cyp3a11 |
cytochrome P450, family 3, subfamily a, polypeptide 11 |
5 |
-145854606 |
BC010528 |
13112 |
63 |
lipid hydroxylation monooxygenase activity monooxygenase activity iron ion binding endoplasmic reticulum endoplasmic reticulum membrane steroid metabolic process steroid metabolic process estrogen metabolic process retinoic acid 4-hydroxylase activity response to bacterium alkaloid catabolic process membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen heme binding demethylase activity xenobiotic catabolic process retinoic acid metabolic process intracellular membrane-bounded organelle metal ion binding testosterone 6-beta-hydroxylase activity testosterone 6-beta-hydroxylase activity aromatase activity oxidative demethylation oxidative demethylation estrogen 16-alpha-hydroxylase activity |
00140 00591 00830 00980 00982 00983 01100 |
| 1420498_a_at |
Dab2 |
disabled 2, mitogen-responsive phosphoprotein |
15 |
6386747, 6299788 |
NM_023118 |
13132 |
128 |
negative regulation of transcription by RNA polymerase II cell morphogenesis fibrillar center in utero embryonic development positive regulation of receptor recycling positive regulation of protein phosphorylation positive regulation of receptor internalization integrin binding protein binding phosphatidylinositol-4,5-bisphosphate binding cytoplasm plasma membrane plasma membrane clathrin-coated pit clathrin-coated pit endocytosis receptor-mediated endocytosis receptor-mediated endocytosis apoptotic process transforming growth factor beta receptor signaling pathway multicellular organism development positive regulation of epithelial to mesenchymal transition positive regulation of epithelial to mesenchymal transition positive regulation of epithelial to mesenchymal transition negative regulation of neuron projection development protein transport membrane Wnt signaling pathway apical plasma membrane myeloid cell differentiation clathrin coat of coated pit clathrin-coated vesicle cell differentiation clathrin binding negative regulation of cell growth positive regulation of cell migration positive regulation of cell migration clathrin-coated vesicle membrane cytoplasmic vesicle negative regulation of protein binding positive regulation of aldosterone biosynthetic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of transcription elongation by RNA polymerase II leading edge cell differentiation phosphatidylinositol binding AP-2 adaptor complex binding clathrin adaptor activity clathrin adaptor activity clathrin adaptor activity cargo receptor activity cargo receptor activity cargo receptor activity negative regulation of apoptotic process negative regulation of apoptotic process intracellular membrane-bounded organelle intracellular membrane-bounded organelle positive regulation of cell adhesion positive regulation of cell adhesion positive regulation of endocytosis positive regulation of endocytosis positive regulation of transcription by RNA polymerase II positive regulation of JNK cascade SMAD binding clathrin coat assembly clathrin coat assembly perinuclear region of cytoplasm response to steroid hormone negative regulation of epithelial cell proliferation low-density lipoprotein particle receptor binding positive regulation of SMAD protein signal transduction negative regulation of androgen receptor signaling pathway negative regulation of ERK1 and ERK2 cascade cellular response to epidermal growth factor stimulus hematopoietic stem cell proliferation cellular response to transforming growth factor beta stimulus negative regulation of canonical Wnt signaling pathway negative regulation of canonical Wnt signaling pathway renal protein absorption extrinsic apoptotic signaling pathway positive regulation of substrate adhesion-dependent cell spreading positive regulation of substrate adhesion-dependent cell spreading positive regulation of substrate adhesion-dependent cell spreading negative regulation of protein localization to plasma membrane negative regulation of protein localization to plasma membrane positive regulation of Wnt signaling pathway, planar cell polarity pathway positive regulation of clathrin-dependent endocytosis positive regulation of clathrin-dependent endocytosis positive regulation of early endosome to late endosome transport positive regulation of aldosterone secretion positive regulation of integrin-mediated signaling pathway negative regulation of extrinsic apoptotic signaling pathway |
04144 |
| 1433743_at |
Dach1 |
dachshund family transcription factor 1 |
14 |
-97786845 |
BG075820 |
13134 |
88 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific suckling behavior DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm transcription regulator complex transcription regulator complex transcription regulator complex cytoplasm Golgi apparatus cytosol regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II multicellular organism development respiratory gaseous exchange by respiratory system negative regulation of transcription by competitive promoter binding nuclear speck negative regulation of cell migration regulation of nuclear cell cycle DNA replication type B pancreatic cell proliferation negative regulation of DNA-templated transcription development of primary female sexual characteristics negative regulation of fibroblast proliferation negative regulation of fibroblast proliferation epithelial cell proliferation negative regulation of cell proliferation involved in contact inhibition negative regulation of DNA biosynthetic process |
|
| 1418762_at |
Cd55 |
CD55 molecule, decay accelerating factor for complement |
1 |
-130439025 |
NM_010016 |
13136 |
115 |
virus receptor activity immune system process positive regulation of T cell cytokine production enzyme inhibitor activity plasma membrane complement activation, classical pathway positive regulation of cytosolic calcium ion concentration lipid binding external side of plasma membrane cell surface membrane apical plasma membrane regulation of complement activation regulation of complement activation, classical pathway regulation of lipopolysaccharide-mediated signaling pathway innate immune response membrane raft negative regulation of complement activation side of membrane regulation of complement-dependent cytotoxicity positive regulation of CD4-positive, alpha-beta T cell activation positive regulation of CD4-positive, alpha-beta T cell proliferation |
04610 04640 05416 |
| 1418578_at |
Dgka |
diacylglycerol kinase, alpha |
10 |
-128720135, -128720135, -128720135, -128720135 |
BC006713 |
13139 |
62 |
nucleotide binding ATP-dependent diacylglycerol kinase activity ATP-dependent diacylglycerol kinase activity ATP-dependent diacylglycerol kinase activity calcium ion binding ATP binding phospholipid binding cytoplasm cytosol cytosol plasma membrane plasma membrane lipid metabolic process phosphatidic acid biosynthetic process signal transduction protein kinase C-activating G protein-coupled receptor signaling pathway lipid binding kinase activity phosphorylation transferase activity intracellular signal transduction diacylglycerol metabolic process diacylglycerol metabolic process glycerolipid metabolic process lipid phosphorylation lipid phosphorylation metal ion binding |
00561 00564 01100 04070 |
| 1422432_at |
Dbi |
diazepam binding inhibitor |
1 |
-120113279, -120113279 |
NM_007830 |
13167 |
78 |
fatty-acyl-CoA binding fatty-acyl-CoA binding behavioral fear response hair follicle development extracellular space mitochondrion endoplasmic reticulum Golgi apparatus fatty acid metabolic process triglyceride metabolic process learning or memory synaptic vesicle lipid binding glial cell proliferation lateral ventricle development benzodiazepine receptor binding negative regulation of fatty acid beta-oxidation regulation of synaptic transmission, GABAergic protein-lipid complex long-chain fatty acyl-CoA binding phosphatidylcholine acyl-chain remodeling identical protein binding contractile fiber skin development positive regulation of lipid biosynthetic process positive regulation of release of sequestered calcium ion into cytosol long-term synaptic potentiation perinuclear endoplasmic reticulum negative regulation of protein lipidation positive regulation of CoA-transferase activity positive regulation of phospholipid transport |
03320 |
| 1438211_s_at |
Dbp |
D site albumin promoter binding protein |
7 |
45705246 |
BB550183 |
13170 |
83 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II circadian rhythm positive regulation of transcription by RNA polymerase II rhythmic process RNA polymerase II transcription regulator complex sequence-specific double-stranded DNA binding |
|
| 1416145_at |
Dhx15 |
DEAH-box helicase 15 |
5 |
-52150202, -52153323 |
BC003745 |
13204 |
47 |
nucleotide binding immune system process nucleic acid binding RNA binding RNA binding RNA helicase activity double-stranded RNA binding helicase activity helicase activity protein binding ATP binding intracellular anatomical structure nucleus spliceosomal complex U12-type spliceosomal complex mRNA processing RNA splicing nuclear speck hydrolase activity defense response to bacterium positive regulation of canonical NF-kappaB signal transduction innate immune response defense response to virus defense response to virus defense response to virus U2-type post-mRNA release spliceosomal complex antiviral innate immune response antiviral innate immune response antiviral innate immune response |
03040 |
| 1423645_a_at |
Ddx5 |
DEAD box helicase 5 |
11 |
-106780355, -106780354, -106780354 |
BC009142 |
13207 |
112 |
negative regulation of transcription by RNA polymerase II nucleotide binding alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome nuclear-transcribed mRNA catabolic process epithelial to mesenchymal transition nucleic acid binding transcription coregulator activity RNA binding RNA helicase activity RNA helicase activity mRNA 3'-UTR binding mRNA 3'-UTR binding helicase activity protein binding calmodulin binding ATP binding nucleus nucleus nucleus nucleoplasm spliceosomal complex nucleolus cytoplasm cytoplasm regulation of transcription by RNA polymerase II mRNA processing protein import into nucleus circadian rhythm RNA splicing mRNA transcription nuclear speck hydrolase activity enzyme binding BMP signaling pathway intracellular estrogen receptor signaling pathway androgen receptor signaling pathway primary miRNA processing MH2 domain binding pre-mRNA binding ribonucleoprotein complex binding ribonucleoprotein complex binding positive regulation of DNA damage response, signal transduction by p53 class mediator regulation of viral genome replication myoblast differentiation regulation of osteoblast differentiation positive regulation of DNA-templated transcription SMAD binding calcium-dependent protein binding rhythmic process nuclear androgen receptor binding regulation of androgen receptor signaling pathway miRNA transcription R-SMAD binding primary miRNA binding catalytic step 2 spliceosome intrinsic apoptotic signaling pathway by p53 class mediator promoter-specific chromatin binding ribonucleoprotein complex ribonucleoprotein complex regulation of skeletal muscle cell differentiation |
03040 |
| 1424936_a_at |
Dnah8 |
dynein, axonemal, heavy chain 8 |
17 |
30626935 |
AF356522 |
13417 |
28 |
nucleotide binding microtubule motor activity ATP binding cytoplasm cytoskeleton microtubule cilium axoneme microtubule-based movement minus-end-directed microtubule motor activity minus-end-directed microtubule motor activity ATP hydrolysis activity dynein complex motile cilium sperm flagellum sperm flagellum outer dynein arm outer dynein arm outer dynein arm assembly cell projection dynein intermediate chain binding dynein intermediate chain binding dynein light intermediate chain binding dynein light intermediate chain binding cilium movement involved in cell motility |
|
| 1438279_at |
Dpp4 |
dipeptidylpeptidase 4 |
2 |
-62330072, -62333222 |
BB532984 |
13482 |
226 |
virus receptor activity behavioral fear response response to hypoxia protease binding B-1a B cell differentiation regulation of T cell mediated immunity positive regulation of natural killer cell mediated immunity aminopeptidase activity serine-type endopeptidase activity signaling receptor binding collagen binding extracellular region plasma membrane plasma membrane proteolysis proteolysis cell adhesion peptidase activity serine-type peptidase activity dipeptidyl-peptidase activity dipeptidyl-peptidase activity positive regulation of cell population proliferation cell surface negative regulation of extracellular matrix disassembly membrane apical plasma membrane hydrolase activity lamellipodium endocytic vesicle protein catabolic process T cell costimulation regulation of cell-cell adhesion mediated by integrin locomotory exploration behavior psychomotor behavior T cell activation peptide binding identical protein binding protein homodimerization activity cell projection endothelial cell migration chemorepellent activity intercellular canaliculus anchoring junction negative regulation of neutrophil chemotaxis |
04974 |
| 1437301_a_at |
Dvl1 |
dishevelled segment polarity protein 1 |
4 |
155847401 |
BB153808 |
13542 |
151 |
regulation of protein phosphorylation negative regulation of protein phosphorylation positive regulation of protein phosphorylation heart looping outflow tract morphogenesis frizzled binding frizzled binding protein binding cytoplasm cytosol cytosol cytosol microtubule plasma membrane neurotransmitter secretion multicellular organism development axonogenesis axon guidance neuromuscular junction development beta-catenin binding positive regulation of neuron projection development postsynaptic density postsynaptic density postsynaptic density microtubule cytoskeleton microtubule cytoskeleton membrane Wnt signaling pathway synaptic vesicle exocytosis lateral plasma membrane enzyme binding protein kinase binding protein kinase binding convergent extension involved in neural plate elongation clathrin-coated vesicle axon axon dendrite growth cone cytoplasmic microtubule organization cytoplasmic microtubule organization small GTPase binding cytoplasmic vesicle cytoplasmic vesicle social behavior protein localization to microtubule intracellular signal transduction identical protein binding neuron projection neuronal cell body receptor clustering dendritic spine synapse collateral sprouting axon extension dendrite morphogenesis synapse organization synapse organization protein stabilization convergent extension involved in organogenesis convergent extension involved in organogenesis canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway Wnt signaling pathway, planar cell polarity pathway Wnt signaling pathway, planar cell polarity pathway prepulse inhibition dendritic spine morphogenesis skeletal muscle acetylcholine-gated channel clustering cochlea morphogenesis planar cell polarity pathway involved in neural tube closure planar cell polarity pathway involved in neural tube closure Schaffer collateral - CA1 synapse Schaffer collateral - CA1 synapse Schaffer collateral - CA1 synapse presynapse presynapse glutamatergic synapse glutamatergic synapse glutamatergic synapse neuronal dense core vesicle neuronal dense core vesicle presynapse assembly presynapse assembly postsynapse organization postsynapse organization regulation of postsynapse organization regulation of postsynapse organization positive regulation of neuron projection arborization Wnt signalosome regulation of synaptic vesicle exocytosis regulation of synaptic vesicle exocytosis regulation of synaptic vesicle exocytosis positive regulation of excitatory postsynaptic potential |
04310 04330 04916 05200 05217 |
| 1417444_at |
E2f5 |
E2F transcription factor 5 |
3 |
14578670 |
BC003220 |
13559 |
59 |
G1/S transition of mitotic cell cycle RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity fibrillar center DNA binding DNA-binding transcription factor activity protein binding nucleus nuclear envelope nucleoplasm nucleoplasm transcription regulator complex nucleolus cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II animal organ morphogenesis sarcoplasm cell projection organization intracellular membrane-bounded organelle sequence-specific DNA binding protein dimerization activity regulation of cell cycle RNA polymerase II transcription regulator complex |
04110 04350 |
| 1416301_a_at |
Ebf1 |
early B cell factor 1 |
11 |
44618099, 44620227 |
BB125261 |
13591 |
257 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II multicellular organism development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II metal ion binding C2H2 zinc finger domain binding |
|
| 1423571_at |
S1pr1 |
sphingosine-1-phosphate receptor 1 |
3 |
-115710432 |
BB133079 |
13609 |
288 |
angiogenesis angiogenesis G protein-coupled receptor binding blood vessel maturation cardiac muscle tissue growth involved in heart morphogenesis sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway G protein-coupled receptor activity nucleoplasm cytoplasm endosome plasma membrane plasma membrane chemotaxis signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway brain development cell population proliferation positive regulation of cell population proliferation external side of plasma membrane membrane cell migration regulation of metabolic process lamellipodium assembly actin cytoskeleton organization regulation of cell adhesion positive regulation of cell migration regulation of bone mineralization leukocyte chemotaxis sphingosine-1-phosphate receptor activity sphingosine-1-phosphate receptor activity sphingosine-1-phosphate receptor activity intracellular membrane-bounded organelle regulation of bone resorption positive regulation of transcription by RNA polymerase II sphingolipid binding positive regulation of smooth muscle cell proliferation positive regulation of positive chemotaxis negative regulation of stress fiber assembly heart trabecula morphogenesis T cell migration |
04080 |
| 1436329_at |
Egr3 |
early growth response 3 |
14 |
70077316, 70077794 |
AV346607 |
13655 |
110 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific positive regulation of endothelial cell proliferation cell migration involved in sprouting angiogenesis DNA binding nucleus nucleoplasm regulation of transcription by RNA polymerase II neuromuscular synaptic transmission peripheral nervous system development positive regulation of T cell differentiation in thymus endothelial cell chemotaxis cellular response to vascular endothelial growth factor stimulus negative regulation of apoptotic process sequence-specific DNA binding cellular response to fibroblast growth factor stimulus regulation of gamma-delta T cell differentiation positive regulation of transcription by RNA polymerase II metal ion binding sequence-specific double-stranded DNA binding |
|
| 1448175_at |
Ehd1 |
EH-domain containing 1 |
19 |
6276895 |
NM_010119 |
13660 |
56 |
nucleotide binding calcium ion binding protein binding ATP binding GTP binding cytoplasm endosome early endosome early endosome lipid droplet plasma membrane plasma membrane cilium intracellular protein transport endocytosis endocytosis endocytosis endosome membrane positive regulation of cholesterol storage positive regulation of neuron projection development protein transport membrane endosomal transport ciliary pocket membrane cell projection organization endocytic vesicle endocytic vesicle platelet dense tubular network membrane neuron projection development small GTPase binding cytoplasmic vesicle early endosome membrane endocytic recycling endocytic recycling low-density lipoprotein particle clearance cholesterol homeostasis identical protein binding cell projection myelin sheath metal ion binding perinuclear region of cytoplasm perinuclear region of cytoplasm protein homooligomerization recycling endosome membrane recycling endosome membrane cilium assembly cilium assembly cilium assembly protein localization to cilium protein localization to plasma membrane positive regulation of myoblast fusion cellular response to nerve growth factor stimulus positive regulation of endocytic recycling |
04144 |
| 1449278_at |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
6 |
70844514, 70844514 |
NM_010121 |
13666 |
287 |
nucleotide binding skeletal system development ossification angiogenesis chondrocyte development protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity eukaryotic translation initiation factor 2alpha kinase activity eukaryotic translation initiation factor 2alpha kinase activity eukaryotic translation initiation factor 2alpha kinase activity eukaryotic translation initiation factor 2alpha kinase activity eukaryotic translation initiation factor 2alpha kinase activity protein binding ATP binding nucleus cytoplasm cytoplasm endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane translation regulation of translation regulation of translational initiation protein phosphorylation protein phosphorylation activation of cysteine-type endopeptidase activity involved in apoptotic process ER overload response response to unfolded protein endoplasmic reticulum organization lactation positive regulation of signal transduction positive regulation of vascular endothelial growth factor production positive regulation of vascular endothelial growth factor production positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression regulation of translational initiation by eIF2 alpha phosphorylation regulation of translational initiation by eIF2 alpha phosphorylation membrane kinase activity phosphorylation transferase activity negative regulation of translation negative regulation of translation negative regulation of translation negative regulation of translation peptidyl-serine phosphorylation regulation of fatty acid metabolic process calcium-mediated signaling enzyme binding protein phosphatase binding bone mineralization endoplasmic reticulum unfolded protein response endoplasmic reticulum unfolded protein response endoplasmic reticulum unfolded protein response endoplasmic reticulum unfolded protein response pancreas development endocrine pancreas development negative regulation of myelination negative regulation of translation in response to stress positive regulation of protein binding SREBP signaling pathway cellular response to amino acid starvation response to endoplasmic reticulum stress response to endoplasmic reticulum stress response to endoplasmic reticulum stress eiF2alpha phosphorylation in response to endoplasmic reticulum stress eiF2alpha phosphorylation in response to endoplasmic reticulum stress eiF2alpha phosphorylation in response to endoplasmic reticulum stress PERK-mediated unfolded protein response cellular response to glucose starvation cellular response to glucose starvation identical protein binding identical protein binding negative regulation of apoptotic process endoplasmic reticulum quality control compartment fat cell differentiation positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase I protein autophosphorylation protein autophosphorylation protein autophosphorylation insulin-like growth factor receptor signaling pathway perinuclear region of cytoplasm Hsp90 protein binding regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress cellular response to cold eukaryotic initiation factor eIF2 binding positive regulation of protein localization to nucleus negative regulation of translation in response to endoplasmic reticulum stress regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway positive regulation of glutathione biosynthetic process positive regulation of ERAD pathway |
04141 05010 05160 |
| 1450934_at |
Eif4a2 |
eukaryotic translation initiation factor 4A2 |
16 |
23107467 |
BM240314 |
13682 |
48 |
nucleotide binding cytoplasmic translational initiation nucleic acid binding RNA binding RNA helicase activity translation initiation factor activity translation initiation factor activity helicase activity ATP binding translation translational initiation eukaryotic translation initiation factor 4F complex hydrolase activity ATP hydrolysis activity perinuclear region of cytoplasm negative regulation of RNA-dependent RNA polymerase activity cellular response to leukemia inhibitory factor |
03013 |
| 1427162_a_at |
Elk4 |
ELK4, member of ETS oncogene family |
1 |
132007619, 132008101, 132008344 |
AW146130 |
13714 |
45 |
negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding chromatin binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm cytosol regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cell differentiation sequence-specific DNA binding positive regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding |
04010 |
| 1451161_a_at |
Adgre1 |
adhesion G protein-coupled receptor E1 |
17 |
57358685 |
U66888 |
13733 |
274 |
adaptive immune response immune system process transmembrane signaling receptor activity G protein-coupled receptor activity G protein-coupled receptor activity calcium ion binding plasma membrane signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway external side of plasma membrane membrane cell periphery |
|
| 1420965_a_at |
Enc1 |
ectodermal-neural cortex 1 |
13 |
97241104 |
BM120053 |
13803 |
44 |
chromatin actin binding nucleus nucleoplasm cytoplasm cytoplasm cytoskeleton multicellular organism development proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-independent protein catabolic process positive regulation of neuron projection development nuclear matrix protein ubiquitination negative regulation of translation Cul3-RING ubiquitin ligase complex Cul3-RING ubiquitin ligase complex neuronal cell body |
|
| 1417338_at |
Epb42 |
erythrocyte membrane protein band 4.2 |
2 |
-121017890 |
U03487 |
13828 |
47 |
cell morphogenesis protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity cytoplasm cytoskeleton plasma membrane regulation of cell shape membrane peptide cross-linking peptide cross-linking hemoglobin metabolic process cortical cytoskeleton erythrocyte maturation spleen development monoatomic ion homeostasis multicellular organismal-level iron ion homeostasis ankyrin-1 complex |
|
| 1418850_at |
Epc1 |
enhancer of polycomb homolog 1 |
18 |
-6488891, -6435950, -6435950 |
NM_007935 |
13831 |
39 |
negative regulation of transcription by RNA polymerase II double-strand break repair via homologous recombination nucleosome nucleus nucleus nucleoplasm nucleolus cytoplasm chromatin organization regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II spermatogenesis spermatid development nuclear body cell differentiation nuclear membrane piccolo histone acetyltransferase complex piccolo histone acetyltransferase complex sperm DNA condensation NuA4 histone acetyltransferase complex site of double-strand break regulation of apoptotic process negative regulation of gene expression, epigenetic negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of striated muscle cell differentiation regulation of cell cycle chromatin-protein adaptor activity enzyme-substrate adaptor activity regulation of chromatin organization positive regulation of double-strand break repair via homologous recombination regulation of double-strand break repair |
|
| 1422438_at |
Ephx1 |
epoxide hydrolase 1, microsomal |
1 |
-180989555 |
NM_010145 |
13849 |
55 |
catalytic activity epoxide hydrolase activity epoxide hydrolase activity endoplasmic reticulum lipid metabolic process cellular aromatic compound metabolic process oxysterol binding response to toxic substance response to organic cyclic compound membrane hydrolase activity ether hydrolase activity arachidonic acid metabolic process arachidonic acid metabolic process aromatic compound catabolic process enzyme binding cis-stilbene-oxide hydrolase activity diol biosynthetic process intracellular membrane-bounded organelle epoxide metabolic process epoxide metabolic process |
00980 04976 |
| 1419406_a_at |
Bcl11a |
BCL11 transcription factor A |
11 |
24080694, 24078055, 24078055 |
NM_016707 |
14025 |
86 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription regulatory region nucleic acid binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription factor activity transcription coregulator activity transcription corepressor activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm regulation of transcription by RNA polymerase II gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of neuron projection development negative regulation of neuron projection development SWI/SNF complex SWI/SNF complex nuclear body protein sumoylation protein kinase binding B cell differentiation T cell differentiation paraspeckles protein homodimerization activity metal ion binding protein heterodimerization activity negative regulation of collateral sprouting positive regulation of collateral sprouting regulation of dendrite development postsynapse DNA-binding transcription factor binding negative regulation of dendrite extension negative regulation of neuron remodeling negative regulation of dendrite development negative regulation of dendrite development negative regulation of branching morphogenesis of a nerve |
|
| 1434920_a_at |
Evl |
Ena-vasodilator stimulated phosphoprotein |
12 |
108605765, 108635752, 108554719 |
AW553781 |
14026 |
50 |
actin binding protein binding profilin binding profilin binding cytoplasm cytoskeleton focal adhesion axon guidance actin polymerization or depolymerization actin polymerization or depolymerization negative regulation of epithelial cell migration SH3 domain binding SH3 domain binding lamellipodium actin filament-based movement platelet activation positive regulation of actin filament polymerization positive regulation of actin filament polymerization cell projection actin nucleation phagocytic vesicle barbed-end actin filament capping protein homotetramerization positive regulation of stress fiber assembly cellular response to type II interferon negative regulation of ruffle assembly |
|
| 1436884_x_at |
Ewsr1 |
Ewing sarcoma breakpoint region 1 |
11 |
-5069686, -5080077 |
BB699868 |
14030 |
101 |
nucleic acid binding transcription coregulator activity RNA binding RNA binding protein binding calmodulin binding nucleus nucleus nucleoplasm nucleolus cytoplasm plasma membrane regulation of DNA-templated transcription Cajal body membrane identical protein binding metal ion binding |
|
| 1417160_s_at |
Wfdc18 |
WAP four-disulfide core domain 18 |
11 |
83709003 |
NM_007969 |
14038 |
20 |
serine-type endopeptidase inhibitor activity extracellular region extracellular space negative regulation of peptidase activity antibacterial humoral response peptidase inhibitor activity innate immune response |
|
| 1435203_at |
Man2a2 |
mannosidase 2, alpha 2 |
7 |
-80349096 |
BB794673 |
140481 |
23 |
Golgi membrane catalytic activity alpha-mannosidase activity alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process N-glycan processing protein deglycosylation metabolic process mannosidase activity membrane hydrolase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding metal ion binding |
00510 01100 |
| 1449305_at |
F10 |
coagulation factor X |
8 |
13037307 |
NM_007972 |
14058 |
53 |
serine-type endopeptidase activity calcium ion binding phospholipid binding extracellular region extracellular space proteolysis blood coagulation hemostasis peptidase activity serine-type peptidase activity hydrolase activity positive regulation of TOR signaling |
04610 |
| 1418897_at |
F2 |
coagulation factor II |
2 |
-91625319 |
NM_010168 |
14061 |
97 |
lipopolysaccharide binding positive regulation of protein phosphorylation endopeptidase activity serine-type endopeptidase activity serine-type endopeptidase activity serine-type endopeptidase activity signaling receptor binding calcium ion binding protein binding extracellular region extracellular space extracellular space proteolysis acute-phase response cell surface receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway blood coagulation hemostasis heparin binding peptidase activity serine-type peptidase activity positive regulation of cell population proliferation regulation of cell shape response to wounding external side of plasma membrane regulation of gene expression hydrolase activity platelet activation platelet activation platelet activation positive regulation of blood coagulation positive regulation of blood coagulation positive regulation of cell growth positive regulation of insulin secretion positive regulation of insulin secretion positive regulation of collagen biosynthetic process fibrinolysis negative regulation of proteolysis negative regulation of astrocyte differentiation positive regulation of release of sequestered calcium ion into cytosol regulation of cytosolic calcium ion concentration cytolysis by host of symbiont cells positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction antimicrobial humoral immune response mediated by antimicrobial peptide collagen-containing extracellular matrix collagen-containing extracellular matrix collagen-containing extracellular matrix thrombospondin receptor activity thrombin-activated receptor signaling pathway neutrophil-mediated killing of gram-negative bacterium positive regulation of lipid kinase activity negative regulation of cytokine production involved in inflammatory response positive regulation of protein localization to nucleus positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway ligand-gated ion channel signaling pathway ligand-gated ion channel signaling pathway positive regulation of reactive oxygen species metabolic process |
04080 04610 04810 |
| 1448931_at |
F2rl1 |
F2R like trypsin receptor 1 |
13 |
-95511729 |
NM_007974 |
14063 |
325 |
proteinase-activated receptor activity G-protein alpha-subunit binding protease binding T cell activation involved in immune response immune system process positive regulation of leukocyte chemotaxis positive regulation of cytokine production involved in immune response positive regulation of glomerular filtration G protein-coupled receptor activity G protein-coupled receptor activity G protein-coupled receptor activity early endosome plasma membrane inflammatory response signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration blood coagulation negative regulation of tumor necrosis factor-mediated signaling pathway thrombin-activated receptor activity membrane regulation of blood coagulation positive regulation of cell migration positive regulation of actin filament depolymerization pseudopodium positive regulation of pseudopodium assembly G-protein beta-subunit binding negative regulation of chemokine production positive regulation of chemokine production positive regulation of chemokine production positive regulation of type II interferon production positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production heterotrimeric G-protein binding positive regulation of superoxide anion generation positive regulation of toll-like receptor 2 signaling pathway negative regulation of toll-like receptor 3 signaling pathway positive regulation of toll-like receptor 3 signaling pathway positive regulation of toll-like receptor 4 signaling pathway positive regulation of Rho protein signal transduction positive regulation of Rho protein signal transduction positive regulation of Rho protein signal transduction neutrophil activation vasodilation vasodilation vasodilation regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of eosinophil degranulation positive regulation of GTPase activity innate immune response cell-cell junction maintenance positive regulation of transcription by RNA polymerase II regulation of JNK cascade negative regulation of JNK cascade positive regulation of JNK cascade negative regulation of insulin secretion negative regulation of insulin secretion leukocyte migration positive regulation of chemotaxis positive regulation of positive chemotaxis defense response to virus defense response to virus positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of phagocytosis, engulfment establishment of endothelial barrier positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade thrombin-activated receptor signaling pathway leukocyte proliferation positive regulation of neutrophil mediated killing of gram-negative bacterium mature conventional dendritic cell differentiation mature conventional dendritic cell differentiation potassium channel activating, G protein-coupled receptor signaling pathway potassium channel activating, G protein-coupled receptor signaling pathway positive regulation of renin secretion into blood stream regulation of chemokine (C-X-C motif) ligand 2 production |
04080 05143 |
| 1454699_at |
Sesn1 |
sestrin 1 |
10 |
41810573, 41887438 |
BG076140 |
140742 |
40 |
fibrillar center protein binding nucleus nucleoplasm cytoplasm positive regulation of macroautophagy oxidoreductase activity oxidoreductase activity, acting on peroxide as acceptor negative regulation of cell growth cellular response to amino acid starvation cellular response to glucose starvation regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GATOR2 complex leucine binding leucine binding cellular response to amino acid stimulus cellular response to leucine reactive oxygen species metabolic process cellular oxidant detoxification regulation of response to reactive oxygen species negative regulation of TORC1 signaling negative regulation of TORC1 signaling negative regulation of TORC1 signaling cellular response to leucine starvation |
04115 |
| 1416514_a_at |
Fscn1 |
fascin actin-bundling protein 1 |
5 |
142960354 |
NM_007984 |
14086 |
77 |
stress fiber ruffle ruffle podosome actin binding protein binding cytoplasm cytoplasm cytosol cytoskeleton microvillus microvillus cell-cell junction actin filament organization cell-cell junction assembly establishment or maintenance of cell polarity positive regulation of lamellipodium assembly actin cytoskeleton actin cytoskeleton cell migration cell migration cell migration lamellipodium lamellipodium lamellipodium microspike assembly actin cytoskeleton organization parallel actin filament bundle assembly filopodium filopodium filopodium dendrite growth cone growth cone growth cone protein-macromolecule adaptor activity cell projection membrane cell projection membrane regulation of microvillus assembly regulation of actin cytoskeleton organization establishment of apical/basal cell polarity cell projection myelin sheath microspike cell motility actin filament binding actin filament binding actin filament binding actin filament bundle assembly actin filament bundle assembly actin filament bundle assembly positive regulation of filopodium assembly positive regulation of filopodium assembly anchoring junction positive regulation of podosome assembly positive regulation of extracellular matrix disassembly |
|
| 1421775_at |
Fcer1a |
Fc receptor, IgE, high affinity I, alpha polypeptide |
1 |
-173221270 |
NM_010184 |
14125 |
145 |
positive regulation of type I hypersensitivity serotonin secretion serotonin secretion protein binding plasma membrane plasma membrane signal transduction cell surface receptor signaling pathway cell surface receptor signaling pathway cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane cell surface membrane immunoglobulin mediated immune response type I hypersensitivity peptidyl-tyrosine phosphorylation leukotriene biosynthetic process calcium-mediated signaling IgE receptor activity IgE receptor activity high-affinity IgE receptor activity high-affinity IgE receptor activity IgE binding IgE binding IgE binding IgE binding granulocyte macrophage colony-stimulating factor production interleukin-3 production positive regulation of granulocyte macrophage colony-stimulating factor production positive regulation of interleukin-3 production mast cell cytokine production positive regulation of mast cell cytokine production type 2 immune response mast cell degranulation mast cell degranulation positive regulation of mast cell degranulation eosinophil degranulation positive regulation of MAP kinase activity positive regulation of JUN kinase activity membrane raft positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling establishment of localization in cell |
04664 05310 |
| 1443264_at |
Ms4a2 |
membrane-spanning 4-domains, subfamily A, member 2 |
19 |
-11615520 |
AV241486 |
14126 |
46 |
endosome plasma membrane plasma membrane immune response signal transduction cell surface receptor signaling pathway cell surface receptor signaling pathway protein kinase C-activating G protein-coupled receptor signaling pathway external side of plasma membrane external side of plasma membrane membrane IgE receptor activity IgE binding protein kinase binding Fc-epsilon receptor I complex Fc-epsilon receptor I complex SH2 domain binding positive regulation of mast cell degranulation membrane raft phosphoprotein binding regulation of release of sequestered calcium ion into cytosol |
04664 05310 |
| 1418340_at |
Fcer1g |
Fc receptor, IgE, high affinity I, gamma polypeptide |
1 |
-171229571 |
NM_010185 |
14127 |
507 |
positive regulation of type IIa hypersensitivity positive regulation of type III hypersensitivity positive regulation of type I hypersensitivity neutrophil activation involved in immune response neutrophil activation involved in immune response T cell differentiation involved in immune response T cell differentiation involved in immune response immune system process Fc receptor mediated stimulatory signaling pathway Fc receptor mediated stimulatory signaling pathway serotonin secretion by platelet transmembrane signaling receptor activity protein binding plasma membrane plasma membrane plasma membrane phagocytosis, engulfment signal transduction cell surface receptor signaling pathway cell surface receptor signaling pathway integrin-mediated signaling pathway external side of plasma membrane external side of plasma membrane cell surface cell surface regulation of platelet activation regulation of platelet activation membrane immunoglobulin mediated immune response immunoglobulin mediated immune response IgE receptor activity IgE receptor activity IgE receptor activity IgE binding IgE binding IgG binding IgG binding antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II osteoclast differentiation neutrophil chemotaxis neutrophil chemotaxis receptor internalization interleukin-2 production interleukin-6 production interleukin-6 production tumor necrosis factor production tumor necrosis factor production positive regulation of interleukin-10 production positive regulation of interleukin-4 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production mast cell cytokine production mast cell cytokine production positive regulation of mast cell cytokine production positive regulation of mast cell cytokine production Fc-epsilon receptor I complex Fc-epsilon receptor I complex Fc-gamma receptor III complex mast cell apoptotic process mast cell apoptotic process negative regulation of mast cell apoptotic process negative regulation of mast cell apoptotic process Fc-gamma receptor signaling pathway Fc-gamma receptor signaling pathway Fc-epsilon receptor signaling pathway interleukin-3-mediated signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I antigen processing and presentation of exogenous peptide antigen via MHC class I defense response to bacterium defense response to bacterium identical protein binding identical protein binding protein homodimerization activity mast cell degranulation mast cell degranulation positive regulation of mast cell degranulation positive regulation of mast cell degranulation innate immune response innate immune response membrane raft mast cell activation mast cell activation metal ion binding protein heterodimerization activity positive regulation of phagocytosis positive regulation of phagocytosis regulation of immune response positive regulation of immune response cellular response to low-density lipoprotein particle stimulus protein localization to plasma membrane positive regulation of protein localization to cell surface positive regulation of protein localization to cell surface |
04650 04664 05310 |
| 1422122_at |
Fcer2a |
Fc receptor, IgE, low affinity II, alpha polypeptide |
8 |
-3681736, -3681736, -3681736 |
M99371 |
14128 |
91 |
B cell antigen processing and presentation positive regulation of humoral immune response mediated by circulating immunoglobulin plasma membrane immune response external side of plasma membrane external side of plasma membrane membrane low-affinity IgE receptor activity IgE binding carbohydrate binding carbohydrate binding macrophage activation biological process involved in interspecies interaction between organisms metal ion binding positive regulation of nitric-oxide synthase activity positive regulation of killing of cells of another organism positive regulation of nitric-oxide synthase biosynthetic process Fc receptor-mediated immune complex endocytosis |
04640 |
| 1417876_at |
Fcgr1 |
Fc receptor, IgG, high affinity I |
3 |
-96282908 |
AF143181 |
14129 |
204 |
antibody-dependent cellular cytotoxicity antibody-dependent cellular cytotoxicity positive regulation of type IIa hypersensitivity positive regulation of type III hypersensitivity immune system process plasma membrane receptor-mediated endocytosis phagocytosis, recognition phagocytosis, engulfment cell surface receptor signaling pathway cell surface receptor signaling pathway response to bacterium external side of plasma membrane external side of plasma membrane membrane IgG receptor activity IgG receptor activity high-affinity IgG receptor activity IgG binding IgG binding antigen processing and presentation of exogenous antigen leukotriene receptor binding antigen processing and presentation of exogenous peptide antigen via MHC class I defense response to bacterium innate immune response positive regulation of phagocytosis regulation of immune response positive regulation of phagocytosis, engulfment |
04145 04380 04640 04666 05140 05150 05322 |
| 1451941_a_at |
Fcgr2b |
Fc receptor, IgG, low affinity IIb |
1 |
-170960558 |
M14216 |
14130 |
504 |
amyloid-beta binding antibody-dependent cellular cytotoxicity negative regulation of type I hypersensitivity immunoglobulin production immune complex clearance negative regulation of immunoglobulin production negative regulation of inflammatory response to antigenic stimulus negative regulation of acute inflammatory response to antigenic stimulus negative regulation of humoral immune response mediated by circulating immunoglobulin protein binding extracellular region cytoplasm cytoskeleton plasma membrane plasma membrane plasma membrane receptor-mediated endocytosis phagocytosis phagocytosis, engulfment defense response cell surface receptor signaling pathway cell surface receptor signaling pathway response to bacterium external side of plasma membrane external side of plasma membrane cell surface membrane immunoglobulin mediated immune response dendrite development IgG receptor activity low-affinity IgG receptor activity IgG binding IgG binding IgG binding immunoglobulin binding antigen processing and presentation of exogenous peptide antigen via MHC class II cerebellum development negative regulation of B cell proliferation endocytic recycling interleukin-10 production negative regulation of interleukin-10 production positive regulation of tumor necrosis factor production negative regulation of neutrophil apoptotic process B cell proliferation dendritic spine cell body protein-containing complex binding positive regulation of JNK cascade regulation of long-term neuronal synaptic plasticity negative regulation of phagocytosis positive regulation of phagocytosis positive regulation of phagocytosis negative regulation of immune response positive regulation of DNA-binding transcription factor activity establishment of localization in cell recycling endosome cellular response to molecule of bacterial origin Fc receptor-mediated immune complex endocytosis regulation of dendritic spine maintenance regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway cellular response to amyloid-beta cellular response to amyloid-beta positive regulation of response to endoplasmic reticulum stress positive regulation of response to endoplasmic reticulum stress |
04145 04380 04662 04666 05150 05322 |
| 1448620_at |
Fcgr3 |
Fc receptor, IgG, low affinity III |
1 |
-171051168, -171051168 |
NM_010188 |
14131 |
254 |
antibody-dependent cellular cytotoxicity antibody-dependent cellular cytotoxicity positive regulation of type IIa hypersensitivity positive regulation of type III hypersensitivity positive regulation of type I hypersensitivity positive regulation of type I hypersensitivity serotonin secretion plasma membrane phagocytosis, recognition phagocytosis, engulfment cell surface receptor signaling pathway cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane cell surface cell surface membrane IgG receptor activity IgG receptor activity IgG receptor activity IgG binding IgG binding neutrophil chemotaxis positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production immunoglobulin receptor binding antigen processing and presentation of exogenous peptide antigen via MHC class I mast cell activation mast cell activation positive regulation of phagocytosis positive regulation of phagocytosis regulation of immune response |
04145 04380 04650 05140 05150 05322 |
| 1418497_at |
Fgf13 |
fibroblast growth factor 13 |
X |
-59062145, -59062145, -59062145, -59062145 |
AF020737 |
14168 |
65 |
MAPK cascade neuron migration nucleus nucleus nucleus cytoplasm cytoplasm cytoplasm cytosol cytosol microtubule plasma membrane sodium ion transport negative regulation of microtubule depolymerization nervous system development learning or memory learning memory microtubule binding growth factor activity intercalated disc membrane lateral plasma membrane sodium channel regulator activity sodium channel regulator activity sodium channel regulator activity hippocampus development cerebral cortex cell migration neurogenesis filopodium protein kinase activator activity axon dendrite growth cone cell projection neuron projection transmembrane transporter binding establishment of neuroblast polarity microtubule polymerization beta-tubulin binding negative regulation of collateral sprouting branching morphogenesis of a nerve protein localization to plasma membrane regulation of cardiac muscle cell action potential involved in regulation of contraction inhibitory synapse assembly regulation of voltage-gated sodium channel activity positive regulation of voltage-gated sodium channel activity |
04010 04810 05200 05218 |
| 1442804_at |
Fgr |
FGR proto-oncogene, Src family tyrosine kinase |
4 |
132974094 |
BB165085 |
14191 |
113 |
nucleotide binding phosphotyrosine residue binding phosphotyrosine residue binding positive regulation of cytokine production immune system process protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity signaling receptor binding protein binding ATP binding cytoplasm mitochondrion mitochondrial inner membrane cytoskeleton plasma membrane plasma membrane protein phosphorylation protein phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway integrin-mediated signaling pathway integrin-mediated signaling pathway integrin-mediated signaling pathway regulation of cell shape actin cytoskeleton membrane aggresome kinase activity phosphorylation transferase activity peptidyl-tyrosine phosphorylation peptidyl-tyrosine phosphorylation protein kinase binding protein kinase binding cell differentiation bone mineralization positive regulation of cell migration ruffle membrane negative regulation of natural killer cell activation regulation of actin cytoskeleton organization immunoglobulin receptor binding Fc-gamma receptor I complex binding cell projection positive regulation of mast cell degranulation innate immune response innate immune response regulation of innate immune response regulation of protein kinase activity protein autophosphorylation skeletal system morphogenesis regulation of phagocytosis defense response to Gram-positive bacterium defense response to Gram-positive bacterium positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
04062 |
| 1424828_a_at |
Fh1 |
fumarate hydratase 1 |
1 |
-175601377 |
BC006048 |
14194 |
58 |
urea cycle regulation of arginine metabolic process catalytic activity fumarate hydratase activity fumarate hydratase activity fumarate hydratase activity nucleus chromosome cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial matrix cytosol tricarboxylic acid cycle tricarboxylic acid cycle tricarboxylic acid cycle fumarate metabolic process fumarate metabolic process fumarate metabolic process malate metabolic process malate metabolic process DNA repair DNA damage response lyase activity site of double-strand break histone binding tricarboxylic acid cycle enzyme complex homeostasis of number of cells within a tissue positive regulation of cold-induced thermogenesis positive regulation of double-strand break repair via nonhomologous end joining |
00020 01100 05200 05211 |
| 1416125_at |
Fkbp5 |
FK506 binding protein 5 |
17 |
-28398752 |
U16959 |
14229 |
134 |
protein peptidyl-prolyl isomerization peptidyl-prolyl cis-trans isomerase activity peptidyl-prolyl cis-trans isomerase activity protein binding nucleus nucleoplasm cytoplasm cytoplasm cytosol response to bacterium isomerase activity heat shock protein binding chaperone-mediated protein folding chaperone-mediated protein folding |
|
| 1418288_at |
Lpin1 |
lipin 1 |
12 |
-16535668, -16535668 |
NM_015763 |
14245 |
138 |
negative regulation of transcription by RNA polymerase II mitochondrial fission transcription coactivator activity transcription coactivator activity protein binding nucleus nucleus transcription regulator complex cytoplasm mitochondrion mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane cytosol lipid metabolic process triglyceride mobilization immune response phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity fatty acid catabolic process fatty acid catabolic process membrane hydrolase activity triglyceride biosynthetic process triglyceride biosynthetic process triglyceride biosynthetic process actin cytoskeleton organization ruffle organization negative regulation of myelination nuclear membrane cellular response to insulin stimulus cellular response to insulin stimulus cellular response to insulin stimulus histone deacetylase binding peroxisome proliferator activated receptor binding cellular lipid metabolic process fat cell differentiation regulation of fat cell differentiation positive regulation of DNA replication positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II phosphatidic acid metabolic process RNA polymerase II-specific DNA-binding transcription factor binding positive regulation of cold-induced thermogenesis |
|
| 1448559_at |
Flot1 |
flotillin 1 |
17 |
35823356 |
NM_008027 |
14251 |
66 |
positive regulation of cytokine production uropod positive regulation of protein phosphorylation protease binding regulation of receptor internalization regulation of receptor internalization regulation of receptor internalization protein binding endosome early endosome microtubule organizing center plasma membrane plasma membrane plasma membrane caveola caveola cell-cell junction adherens junction endocytosis axonogenesis axon guidance COP9 signalosome external side of plasma membrane membrane basolateral plasma membrane flotillin complex flotillin complex flotillin complex extracellular matrix disassembly lamellipodium cortical actin cytoskeleton cytoplasmic vesicle cytoplasmic vesicle positive regulation of protein binding positive regulation of protein binding positive regulation of synaptic transmission, dopaminergic positive regulation of interferon-beta production dsRNA transport positive regulation of heterotypic cell-cell adhesion positive regulation of toll-like receptor 3 signaling pathway centriolar satellite response to endoplasmic reticulum stress regulation of Rho protein signal transduction ionotropic glutamate receptor binding sarcolemma positive regulation of canonical NF-kappaB signal transduction cell-cell contact zone plasma membrane raft plasma membrane raft assembly plasma membrane raft organization membrane raft membrane raft synapse positive regulation of endocytosis positive regulation of endocytosis positive regulation of endocytosis positive regulation of skeletal muscle tissue development positive regulation of skeletal muscle tissue development presynaptic active zone protein stabilization regulation of neurotransmitter uptake protein kinase C signaling protein kinase C signaling protein kinase C signaling cellular response to exogenous dsRNA protein localization to plasma membrane protein localization to plasma membrane protein localization to plasma membrane dopaminergic synapse presynapse glutamatergic synapse GABA-ergic synapse positive regulation of myoblast fusion positive regulation of myoblast fusion positive regulation of cell junction assembly positive regulation of cell junction assembly positive regulation of cell junction assembly positive regulation of cell-cell adhesion mediated by cadherin positive regulation of cell-cell adhesion mediated by cadherin positive regulation of cell-cell adhesion mediated by cadherin |
04910 |
| 1438164_x_at |
Flot2 |
flotillin 2 |
11 |
78037930 |
BB118974 |
14252 |
60 |
uropod protease binding acrosomal membrane endosome plasma membrane plasma membrane caveola caveola adherens junction cell adhesion negative regulation of gene expression membrane basolateral plasma membrane flotillin complex flotillin complex flotillin complex lamellipodium endocytic vesicle cortical actin cytoskeleton cytoplasmic vesicle cytoplasmic vesicle cytoplasmic vesicle vesicle ionotropic glutamate receptor binding positive regulation of canonical NF-kappaB signal transduction intracellular membrane-bounded organelle cell-cell contact zone protein localization to plasma membrane raft membrane raft synapse regulation of myoblast differentiation regulation of myoblast differentiation perinuclear region of cytoplasm presynaptic active zone membrane protein stabilization protein localization to plasma membrane protein localization to plasma membrane anterograde dendritic transport anterograde dendritic transport glutamatergic synapse glutamatergic synapse glutamatergic synapse regulation of postsynaptic membrane neurotransmitter receptor levels regulation of postsynaptic membrane neurotransmitter receptor levels negative regulation of amyloid precursor protein catabolic process positive regulation of establishment of T cell polarity |
04910 |
| 1437247_at |
Fosl2 |
fos-like antigen 2 |
5 |
32136471 |
BM245170 |
14284 |
72 |
cell morphogenesis transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific ossification osteoblast differentiation response to hypoxia response to hypoxia cytokine production cytokine production NK T cell differentiation chondrocyte differentiation inflammatory response to antigenic stimulus keratinocyte development growth plate cartilage development DNA binding chromatin binding double-stranded DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II inflammatory response inflammatory response response to xenobiotic stimulus gene expression gene expression B cell differentiation T cell differentiation neutrophil differentiation macrophage differentiation macrophage differentiation bone mineralization osteoclast differentiation lung development response to estradiol response to lipopolysaccharide chemokine production granulocyte macrophage colony-stimulating factor production interleukin-2 production interleukin-4 production collagen metabolic process collagen biosynthetic process multicellular organism growth T-helper 2 cell cytokine production response to interleukin-13 chondrocyte proliferation myofibroblast differentiation regulation of multicellular organism growth regulation of multicellular organism growth B cell proliferation glucose homeostasis sequence-specific DNA binding innate immune response fat cell differentiation positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of fibroblast proliferation lung alveolus development smooth muscle tissue development tissue remodeling homeostasis of number of cells homeostasis of number of cells within a tissue homeostasis of number of cells within a tissue T cell receptor signaling pathway T cell receptor signaling pathway cartilage development response to glucocorticoid bone development bone development lung connective tissue development fat pad development alveolar secondary septum development mucus secretion chemokine (C-C motif) ligand 11 production RNA polymerase II transcription regulator complex response to interleukin-7 response to Gram-positive bacterium insulin metabolic process fat cell apoptotic process regulation of myofibroblast differentiation regulation of myofibroblast differentiation response to bleomycin response to leukemia inhibitory factor |
04380 |
| 1422953_at |
Fpr2 |
formyl peptide receptor 2 |
17 |
17887823 |
NM_008039 |
14289 |
126 |
amyloid-beta binding amyloid-beta binding positive regulation of protein phosphorylation complement receptor mediated signaling pathway immune response-regulating cell surface receptor signaling pathway complement receptor activity G protein-coupled receptor activity N-formyl peptide receptor activity N-formyl peptide receptor activity scavenger receptor binding cytoplasm plasma membrane plasma membrane chemotaxis inflammatory response signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration membrane calcium-mediated signaling positive regulation of superoxide anion generation signaling receptor activity signaling receptor activity defense response to bacterium positive regulation of innate immune response negative regulation of inflammatory response positive regulation of phagocytosis RAGE receptor binding positive chemotaxis positive regulation of ERK1 and ERK2 cascade positive regulation of monocyte chemotaxis cellular response to amyloid-beta cellular response to amyloid-beta |
04080 05150 |
| 1450808_at |
Fpr1 |
formyl peptide receptor 1 |
17 |
-17876470 |
NM_013521 |
14293 |
88 |
G protein-coupled receptor binding complement receptor mediated signaling pathway complement receptor activity G protein-coupled receptor activity N-formyl peptide receptor activity N-formyl peptide receptor activity N-formyl peptide receptor activity scavenger receptor binding cytoplasm plasma membrane plasma membrane chemotaxis inflammatory response signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration membrane RAGE receptor binding |
04080 05150 |
| 1425822_a_at |
Dtx1 |
deltex 1, E3 ubiquitin ligase |
5 |
-120680263 |
AB015422 |
14357 |
44 |
Notch binding protein binding nucleus nucleoplasm nucleoplasm cytoplasm cytosol cytosol Notch signaling pathway Notch signaling pathway Notch signaling pathway zinc ion binding regulation of Notch signaling pathway glial cell differentiation protein ubiquitination protein ubiquitination nuclear body transferase activity SH3 domain binding T cell differentiation ubiquitin protein ligase binding negative regulation of T cell differentiation negative regulation of neuron differentiation metal ion binding ubiquitin protein ligase activity cellular response to leukemia inhibitory factor |
04330 |
| 1448700_at |
G0s2 |
G0/G1 switch gene 2 |
1 |
-193272159 |
NM_008059 |
14373 |
36 |
mitochondrion mitochondrion apoptotic process extrinsic apoptotic signaling pathway positive regulation of cold-induced thermogenesis positive regulation of extrinsic apoptotic signaling pathway positive regulation of extrinsic apoptotic signaling pathway |
|
| 1448354_at |
G6pdx |
glucose-6-phosphate dehydrogenase X-linked |
X |
-74409482 |
NM_008062 |
14381 |
146 |
cytokine production angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure glucose-6-phosphate dehydrogenase activity glucose-6-phosphate dehydrogenase activity glucose-6-phosphate dehydrogenase activity glucose-6-phosphate dehydrogenase activity glucose binding cytoplasm cytosol cytosol cytosol carbohydrate metabolic process glucose metabolic process glucose metabolic process pentose-phosphate shunt cholesterol biosynthetic process NADP metabolic process NADPH regeneration NADP biosynthetic process NADP biosynthetic process glutathione metabolic process glutathione metabolic process response to oxidative stress pentose-phosphate shunt, oxidative branch pentose-phosphate shunt, oxidative branch pentose-phosphate shunt, oxidative branch cytoplasmic side of plasma membrane negative regulation of protein glutathionylation membrane oxidoreductase activity oxidoreductase activity, acting on CH-OH group of donors pentose biosynthetic process pentose biosynthetic process pentose biosynthetic process carbohydrate binding interleukin-10 production interleukin-12 production centriolar satellite cellular response to oxidative stress regulation of multicellular organism growth identical protein binding identical protein binding protein homodimerization activity intracellular membrane-bounded organelle erythrocyte maturation regulation of neuron apoptotic process response to ethanol ribose phosphate biosynthetic process erythrocyte development NADP binding glucose 6-phosphate metabolic process negative regulation of cell growth involved in cardiac muscle cell development positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel negative regulation of reactive oxygen species metabolic process |
00030 00480 01100 |
| 1417694_at |
Gab1 |
growth factor receptor bound protein 2-associated protein 1 |
8 |
-80764433, -80764430 |
NM_021356 |
14388 |
107 |
MAPK cascade angiogenesis protein binding cytoplasm cytoplasm cytosol cell-cell junction cell cortex response to oxidative stress signal transduction signal transduction epidermal growth factor receptor signaling pathway heart development epidermis development regulation of cell migration signaling adaptor activity signaling adaptor activity signaling adaptor activity response to hepatocyte growth factor cellular response to vascular endothelial growth factor stimulus vascular endothelial growth factor signaling pathway positive regulation of cell migration by vascular endothelial growth factor signaling pathway positive regulation of MAP kinase activity positive regulation of MAPK cascade positive regulation of MAPK cascade positive regulation of angiogenesis platelet-derived growth factor receptor signaling pathway labyrinthine layer development interleukin-6-mediated signaling pathway endothelial cell chemotaxis to vascular endothelial growth factor |
04012 04722 05100 05211 |
| 1418655_at |
B4galnt1 |
beta-1,4-N-acetyl-galactosaminyl transferase 1 |
10 |
127165155, 127165830, 127165830, 127165155 |
U18975 |
14421 |
105 |
Golgi membrane ganglioside biosynthetic process ganglioside biosynthetic process ganglioside biosynthetic process ganglioside biosynthetic process (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity Golgi apparatus lipid metabolic process sphingolipid metabolic process glycosphingolipid metabolic process glycosphingolipid metabolic process glycosphingolipid biosynthetic process vacuole organization spermatogenesis determination of adult lifespan acetylgalactosaminyltransferase activity acetylgalactosaminyltransferase activity membrane transferase activity glycosyltransferase activity hexosyltransferase activity lipid storage nerve development lipid glycosylation limb development motor behavior |
00604 01100 |
| 1436222_at |
Gas5 |
growth arrest specific 5 |
1 |
161035165, 161034600 |
AW547050 |
14455 |
83 |
molecular_function cellular_component response to bacterium |
|
| 1448886_at |
Gata3 |
GATA binding protein 3 |
2 |
-9857077 |
NM_008091 |
14462 |
602 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin cell morphogenesis transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding cis-regulatory region sequence-specific DNA binding transcription coactivator binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific in utero embryonic development cell fate determination neuron migration cell activation regulation of cytokine production positive regulation of cytokine production kidney development mesonephros development lens development in camera-type eye immune system process immune system development pro-T cell differentiation aortic valve morphogenesis cardiac right ventricle morphogenesis ventricular septum development DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity interleukin-2 receptor binding protein binding nucleus nucleus nucleoplasm chromatin remodeling chromatin remodeling regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II inflammatory response humoral immune response signal transduction nervous system development axon guidance zinc ion binding cell population proliferation negative regulation of cell population proliferation male gonad development post-embryonic development positive regulation of signal transduction gene expression positive regulation of endothelial cell migration positive regulation of gene expression negative regulation of gene expression negative regulation of epithelial to mesenchymal transition regulation of neuron projection development neuron differentiation T cell differentiation T cell differentiation erythrocyte differentiation macrophage differentiation regulation of epithelial cell differentiation TOR signaling type II interferon production interleukin-13 production interleukin-4 production interleukin-4 production interleukin-5 production negative regulation of type II interferon production negative regulation of type II interferon production negative regulation of interleukin-2 production positive regulation of interleukin-13 production positive regulation of interleukin-13 production positive regulation of interleukin-4 production positive regulation of interleukin-4 production positive regulation of interleukin-5 production positive regulation of interleukin-5 production T cell differentiation in thymus T cell differentiation in thymus negative regulation of mammary gland epithelial cell proliferation embryonic hemopoiesis embryonic hemopoiesis ureter maturation parathyroid hormone secretion norepinephrine biosynthetic process inner ear morphogenesis identical protein binding phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of neuron apoptotic process sequence-specific DNA binding sequence-specific DNA binding ear development thymic T cell selection T-helper 2 cell differentiation T-helper 2 cell differentiation innate immune response cell fate commitment positive regulation of T cell differentiation positive regulation of cell differentiation regulation of T-helper cell differentiation negative regulation of cell cycle negative regulation of cell cycle negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding cell maturation sympathetic nervous system development thymus development embryonic organ development embryonic organ development developmental growth anatomical structure formation involved in morphogenesis homeostasis of number of cells negative regulation of inflammatory response T cell receptor signaling pathway cartilage development positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction parathyroid gland development pharyngeal system development uterus development mesenchymal to epithelial transition mast cell differentiation ureteric bud formation RNA polymerase II-specific DNA-binding transcription factor binding E-box binding cellular response to cytokine stimulus cellular response to interleukin-4 cellular response to interleukin-4 otic vesicle development cellular response to BMP stimulus HMG box domain binding positive regulation of ureteric bud formation nephric duct morphogenesis nephric duct formation regulation of nephron tubule epithelial cell differentiation ureter morphogenesis lymphocyte migration negative regulation of DNA demethylation negative regulation of DNA demethylation positive regulation of miRNA transcription histone methyltransferase binding sequence-specific double-stranded DNA binding regulation of establishment of cell polarity negative regulation of cell motility negative regulation of endothelial cell apoptotic process positive regulation of T-helper 2 cell cytokine production negative regulation of cell proliferation involved in mesonephros development positive regulation of thyroid hormone generation positive regulation of transcription regulatory region DNA binding positive regulation of transcription regulatory region DNA binding regulation of cellular response to X-ray negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation |
|
| 1420549_at |
Gbp2b |
guanylate binding protein 2b |
3 |
142594846 |
NM_010259 |
14468 |
45 |
Golgi membrane nucleotide binding activation of innate immune response immune system process actin binding GTPase activity GTPase activity GTPase activity G protein activity GDP phosphatase activity endopeptidase inhibitor activity protein binding GTP binding GTP binding extracellular region nucleus nucleoplasm cytoplasm Golgi apparatus cytosol plasma membrane vesicle membrane actin cytoskeleton membrane hydrolase activity GMP binding GDP binding enzyme binding cytokine binding symbiont-containing vacuole membrane spectrin binding cytoplasmic vesicle cytoplasmic vesicle cytoplasmic vesicle cellular response to interferon-beta defense response to bacterium identical protein binding protein homodimerization activity defense response to protozoan defense response to protozoan adhesion of symbiont to host innate immune response perinuclear region of cytoplasm defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to virus cytolysis in another organism Hsp90 protein binding cellular response to lipopolysaccharide cellular response to type II interferon cellular response to type II interferon symbiont cell surface positive regulation of pyroptosis molecular function inhibitor activity |
|
| 1435906_x_at |
Gbp2 |
guanylate binding protein 2 |
3 |
142620662 |
BE197524 |
14469 |
65 |
Golgi membrane nucleotide binding activation of innate immune response immune system process actin binding GTPase activity GTPase activity GTPase activity G protein activity G protein activity GDP phosphatase activity endopeptidase inhibitor activity GTP binding GTP binding nucleus nucleoplasm cytoplasm Golgi apparatus cytosol protein targeting response to bacterium vesicle membrane actin cytoskeleton membrane hydrolase activity GDP binding enzyme binding cytokine binding symbiont-containing vacuole membrane spectrin binding GTPase regulator activity cytoplasmic vesicle cytoplasmic vesicle cytoplasmic vesicle cellular response to interferon-beta defense response to bacterium defense response to bacterium identical protein binding protein homodimerization activity defense response to protozoan defense response to protozoan adhesion of symbiont to host innate immune response perinuclear region of cytoplasm defense response to Gram-positive bacterium defense response to Gram-positive bacterium cytolysis in another organism cytolysis in another organism Hsp90 protein binding cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to type II interferon cellular response to type II interferon symbiont cell surface symbiont cell surface positive regulation of pyroptosis positive regulation of pyroptosis molecular function inhibitor activity positive regulation of AIM2 inflammasome complex assembly |
|
| 1419595_a_at |
Ggh |
gamma-glutamyl hydrolase |
4 |
20042051 |
NM_010281 |
14590 |
21 |
extracellular region extracellular space extracellular space lysosome vacuole peptidase activity omega peptidase activity response to xenobiotic stimulus response to zinc ion hydrolase activity response to insulin gamma-glutamyl-peptidase activity gamma-glutamyl-peptidase activity response to ethanol tetrahydrofolylpolyglutamate metabolic process |
00790 |
| 1448485_at |
Ggt1 |
gamma-glutamyltransferase 1 |
10 |
75573494, 75568661, 75564131, 75571559 |
NM_008116 |
14598 |
69 |
peptidyltransferase activity regulation of immune system process regulation of immune system process leukotriene-C(4) hydrolase extracellular space endoplasmic reticulum plasma membrane plasma membrane plasma membrane proteolysis glutathione metabolic process glutathione biosynthetic process glutathione catabolic process glutathione catabolic process spermatogenesis peptidase activity membrane transferase activity acyltransferase activity aminoacyltransferase activity hydrolase activity cysteine biosynthetic process peptide modification peptide modification vesicle glutathione hydrolase activity glutathione hydrolase activity perinuclear region of cytoplasm regulation of inflammatory response regulation of inflammatory response leukotriene C4 gamma-glutamyl transferase activity |
00430 00460 00480 00590 01100 |
| 1417962_s_at |
Ghr |
growth hormone receptor |
15 |
-3327524, -3317754, -3317754 |
NM_010284 |
14600 |
313 |
cytokine receptor activity growth hormone receptor activity growth hormone receptor activity growth hormone receptor activity protein binding extracellular region extracellular region extracellular space extracellular space nucleus cytosol cytosol plasma membrane plasma membrane plasma membrane endocytosis receptor signaling pathway via JAK-STAT lipid binding hormone-mediated signaling pathway external side of plasma membrane cell surface membrane membrane peptide hormone binding peptide hormone binding peptide hormone binding cytokine-mediated signaling pathway cytokine-mediated signaling pathway taurine metabolic process growth factor binding growth factor binding protein kinase binding protein phosphatase binding cytokine binding regulation of response to nutrient levels response to estradiol cellular response to hormone stimulus cytoplasmic ribonucleoprotein granule regulation of multicellular organism growth positive regulation of multicellular organism growth SH2 domain binding hormone metabolic process identical protein binding protein homodimerization activity neuronal cell body receptor complex positive regulation of receptor signaling pathway via JAK-STAT positive regulation of receptor signaling pathway via JAK-STAT insulin-like growth factor receptor signaling pathway positive regulation of peptidyl-tyrosine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation growth hormone receptor signaling pathway growth hormone receptor signaling pathway growth hormone receptor signaling pathway growth hormone receptor complex growth hormone receptor complex |
04060 04080 04630 |
| 1426235_a_at |
Glul |
glutamate-ammonia ligase |
1 |
153899928 |
AI391218 |
14645 |
247 |
nucleotide binding magnesium ion binding angiogenesis catalytic activity glutamine synthetase activity glutamine synthetase activity protein binding ATP binding cytoplasm cytoplasm mitochondrion mitochondrion endoplasmic reticulum cytosol plasma membrane glutamate metabolic process glutamine biosynthetic process glutamine biosynthetic process nitrogen compound metabolic process cell population proliferation cellular response to starvation response to glucose regulation of endothelial cell migration regulation of endothelial cell migration membrane nickel cation binding glutamate binding transferase activity ligase activity protein palmitoylation ammonia assimilation cycle protein-cysteine S-palmitoyltransferase activity manganese ion binding positive regulation of insulin secretion protein-containing complex ribosome biogenesis identical protein binding cell projection perikaryon myelin sheath myelin sheath intracellular membrane-bounded organelle axon terminus cell body dynein light chain binding metal ion binding positive regulation of epithelial cell proliferation positive regulation of synaptic transmission, glutamatergic glial cell projection regulation of sprouting angiogenesis regulation of sprouting angiogenesis regulation of protein localization to nucleolus |
00250 00330 00910 01100 |
| 1421947_at |
Gng12 |
guanine nucleotide binding protein (G protein), gamma 12 |
6 |
66896396, 66896890 |
NM_025278 |
14701 |
32 |
heterotrimeric G-protein complex heterotrimeric G-protein complex actin filament plasma membrane signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway membrane PDZ domain binding G-protein beta-subunit binding G-protein beta-subunit binding phosphate ion binding |
04010 04062 04810 |
| 1428733_at |
Gngt2 |
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 |
11 |
95842667, 95842294, 95843244 |
AK010554 |
14710 |
25 |
heterotrimeric G-protein complex heterotrimeric G-protein complex plasma membrane signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway membrane G-protein beta-subunit binding G-protein beta-subunit binding |
04062 |
| 1456887_at |
Cmklr1 |
chemerin chemokine-like receptor 1 |
5 |
-113612354, -113612354 |
AW228687 |
14747 |
83 |
complement receptor mediated signaling pathway complement receptor activity G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane chemotaxis chemotaxis inflammatory response signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of macrophage chemotaxis positive regulation of macrophage chemotaxis membrane negative regulation of NF-kappaB transcription factor activity negative regulation of interleukin-12 production positive regulation of fat cell differentiation regulation of calcium-mediated signaling regulation of calcium-mediated signaling adipokinetic hormone receptor activity adipokinetic hormone binding positive regulation of cold-induced thermogenesis |
|
| 1450081_x_at |
Gpi1 |
glucose-6-phosphate isomerase 1 |
7 |
-34201326 |
NM_008155 |
14751 |
239 |
in utero embryonic development mesoderm formation positive regulation of immunoglobulin production glucose-6-phosphate isomerase activity glucose-6-phosphate isomerase activity glucose-6-phosphate isomerase activity glucose-6-phosphate isomerase activity cytokine activity protein binding extracellular region extracellular space cytoplasm cytosol cytosol plasma membrane gluconeogenesis gluconeogenesis glycolytic process glycolytic process glycolytic process growth factor activity positive regulation of endothelial cell migration isomerase activity ubiquitin protein ligase binding erythrocyte homeostasis glucose homeostasis myelin sheath negative regulation of neuron apoptotic process monosaccharide binding monosaccharide binding glucose 6-phosphate metabolic process glucose 6-phosphate metabolic process ciliary membrane glycolytic process through glucose-6-phosphate canonical glycolysis carbohydrate derivative binding carbohydrate derivative metabolic process |
00010 00030 00500 00520 01100 |
| 1434848_at |
Gpr27 |
G protein-coupled receptor 27 |
6 |
99692366 |
BB259283 |
14761 |
9 |
G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane positive regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway |
|
| 1421816_at |
Gsr |
glutathione reductase |
8 |
33653237 |
AK019177 |
14782 |
83 |
glutathione-disulfide reductase (NADP) activity glutathione-disulfide reductase (NADP) activity glutathione-disulfide reductase (NADP) activity cytoplasm mitochondrion mitochondrion cytosol cytosol glutathione metabolic process glutathione metabolic process glutathione metabolic process spermatogenesis external side of plasma membrane oxidoreductase activity oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor cellular response to oxidative stress identical protein binding glutathione binding cell redox homeostasis cell redox homeostasis flavin adenine dinucleotide binding flavin adenine dinucleotide binding NADP binding cellular oxidant detoxification |
00480 |
| 1448148_at |
Grn |
granulin |
11 |
102430506 |
M86736 |
14824 |
257 |
trophectodermal cell proliferation blastocyst hatching astrocyte activation involved in immune response microglial cell activation involved in immune response cytokine activity protein binding extracellular region extracellular region extracellular region extracellular space extracellular space extracellular space mitochondrion lysosome lysosome lysosomal membrane endosome late endosome endoplasmic reticulum endoplasmic reticulum Golgi apparatus Golgi apparatus trans-Golgi network plasma membrane lysosome organization lysosomal transport lysosomal transport lysosomal lumen acidification embryo implantation positive regulation of cell population proliferation positive regulation of endothelial cell migration positive regulation of neuron projection development membrane positive regulation of cell migration vesicle response to estradiol locomotory exploration behavior chondrocyte proliferation negative regulation of neuron apoptotic process positive regulation of neuron apoptotic process synapse positive regulation of angiogenesis negative regulation of innate immune response synaptic vesicle endocytosis positive regulation of axon regeneration epithelial cell proliferation positive regulation of epithelial cell proliferation positive regulation of epithelial cell proliferation regulation of inflammatory response negative regulation of inflammatory response protein stabilization protein-folding chaperone binding negative regulation of hydrolase activity retina development in camera-type eye male mating behavior negative regulation of respiratory burst involved in inflammatory response positive regulation of dendritic spine development neural precursor cell proliferation glutamatergic synapse maintenance of synapse structure maintenance of synapse structure positive regulation of inflammatory response to wounding cerebellar climbing fiber to Purkinje cell synapse cerebellar climbing fiber to Purkinje cell synapse positive regulation of defense response to bacterium negative regulation of neutrophil activation positive regulation of protein folding negative regulation of microglial cell activation positive regulation of trophectodermal cell proliferation lysosomal protein catabolic process positive regulation of aspartic-type peptidase activity positive regulation of aspartic-type peptidase activity regulation of lysosome organization positive regulation of lysosome organization positive regulation of lysosome organization |
|
| 1423423_at |
Pdia3 |
protein disulfide isomerase associated 3 |
2 |
121413901 |
BF319868 |
14827 |
128 |
acrosomal vesicle adaptive immune response immune system process peptide antigen assembly with MHC class I protein complex protein disulfide isomerase activity protein disulfide isomerase activity protein binding extracellular region extracellular space endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum lumen smooth endoplasmic reticulum protein folding peptidase activity cell surface cell surface cell surface protein-disulfide reductase activity apical plasma membrane isomerase activity protein-disulfide reductase (glutathione) activity response to endoplasmic reticulum stress MHC class I protein binding identical protein binding MHC class I peptide loading complex TAP complex myelin sheath Tapasin-ERp57 complex platelet aggregation cellular response to vitamin D extrinsic apoptotic signaling pathway cellular response to interleukin-7 positive regulation of protein folding positive regulation of extrinsic apoptotic signaling pathway |
04141 04612 |
| 1448330_at |
Gstm1 |
glutathione S-transferase, mu 1 |
3 |
-108012249, -108012259 |
NM_010358 |
14862 |
48 |
glutathione transferase activity glutathione transferase activity steroid binding protein binding extracellular region cytoplasm cytosol lipid metabolic process glutathione metabolic process glutathione metabolic process nickel cation binding transferase activity enzyme binding protein kinase binding protein-containing complex xenobiotic catabolic process identical protein binding identical protein binding protein homodimerization activity myelin sheath glutathione binding intercellular bridge cellular response to xenobiotic stimulus |
00480 00980 00982 |
| 1417883_at |
Gstt2 |
glutathione S-transferase, theta 2 |
10 |
-75831844 |
BC012707 |
14872 |
26 |
glutathione transferase activity glutathione transferase activity glutathione peroxidase activity nucleus cytoplasm cytoplasm cytosol cytosol glutathione metabolic process glutathione metabolic process transferase activity cellular response to leukemia inhibitory factor |
00480 00980 00982 |
| 1425628_a_at |
Gtf2i |
general transcription factor II I |
5 |
-134237831, -134237831 |
AF043220 |
14886 |
91 |
DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm transcription by RNA polymerase II embryo development negative regulation of angiogenesis positive regulation of transcription by RNA polymerase II negative regulation of cytosolic calcium ion concentration RNA polymerase II-specific DNA-binding transcription factor binding |
03022 |
| 1452896_at |
Cfap20 |
cilia and flagella associated protein 20 |
8 |
-95420249 |
AK011217 |
14894 |
22 |
nucleus nucleoplasm cytoplasm centriole cytoskeleton microtubule axonemal microtubule cilium cilium protein polyglutamylation motile cilium ciliary basal body ciliary basal body cell projection cilium assembly cilium assembly regulation of cilium beat frequency involved in ciliary motility regulation of cilium beat frequency involved in ciliary motility axonemal B tubule inner sheath positive regulation of cell motility positive regulation of cell motility positive regulation of feeding behavior |
|
| 1422703_at |
Gk |
glycerol kinase |
X |
-85701936 |
BF683028 |
14933 |
50 |
nucleotide binding glycerol kinase activity glycerol kinase activity glycerol kinase activity glycerol kinase activity ATP binding nucleus cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial outer membrane cytosol cytosol carbohydrate metabolic process glycerol metabolic process glycerol metabolic process glycerol metabolic process glycerol-3-phosphate metabolic process triglyceride metabolic process triglyceride metabolic process membrane kinase activity phosphorylation phosphorylation transferase activity phosphotransferase activity, alcohol group as acceptor regulation of fatty acid metabolic process triglyceride biosynthetic process histone binding glucose homeostasis response to ethanol glycerol-3-phosphate biosynthetic process glycerol-3-phosphate biosynthetic process |
00561 01100 03320 |
| 1425643_at |
Gypa |
glycophorin A |
8 |
80494044 |
M26385 |
14934 |
37 |
nucleoplasm cytosol plasma membrane plasma membrane external side of plasma membrane membrane identical protein binding identical protein binding regulation of response to osmotic stress ankyrin-1 complex |
05144 |
| 1452431_s_at |
H2-Aa |
histocompatibility 2, class II antigen A, alpha |
17 |
-34282743 |
AF119253 |
14960 |
123 |
adaptive immune response immune system process peptide antigen assembly with MHC class II protein complex antigen processing and presentation of peptide or polysaccharide antigen via MHC class II protein binding lysosome lysosomal membrane plasma membrane immune response external side of plasma membrane membrane antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding late endosome membrane response to type II interferon negative regulation of T cell proliferation peptide antigen binding peptide antigen binding MHC class II protein complex MHC class II protein complex protein-containing complex binding positive regulation of T cell differentiation antigen processing and presentation of peptide antigen positive regulation of immune response positive regulation of T cell activation |
04145 04514 04612 04672 04940 05140 05145 05150 05310 05320 05322 05323 05330 05332 05416 |
| 1451721_a_at |
H2-Ab1 |
histocompatibility 2, class II antigen A, beta 1 |
17 |
34263226 |
M15848 |
14961 |
868 |
adaptive immune response B cell affinity maturation immune system process peptide antigen assembly with MHC class II protein complex antigen processing and presentation of peptide or polysaccharide antigen via MHC class II positive regulation of antigen processing and presentation positive regulation of T-helper 1 type immune response protein binding intracellular anatomical structure lysosomal membrane early endosome multivesicular body Golgi apparatus plasma membrane immune response external side of plasma membrane cell surface toxic substance binding membrane antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding ubiquitin protein ligase binding late endosome membrane peptide antigen binding peptide antigen binding MHC class II protein complex MHC class II protein complex protein-containing complex binding positive regulation of alpha-beta T cell activation positive regulation of alpha-beta T cell activation positive regulation of alpha-beta T cell activation antigen processing and presentation of peptide antigen positive regulation of immune response positive regulation of T cell activation cellular response to type II interferon protein antigen binding |
04145 04514 04612 04672 04940 05140 05145 05150 05310 05320 05322 05323 05330 05332 05416 |
| 1417314_at |
Cfb |
complement factor B |
17 |
-34856373 |
NM_008198 |
14962 |
182 |
immune system process serine-type endopeptidase activity extracellular region proteolysis complement activation complement activation complement activation, alternative pathway complement activation, alternative pathway complement activation, alternative pathway peptidase activity serine-type peptidase activity response to bacterium hydrolase activity B cell proliferation innate immune response |
04610 05150 |
| 1417025_at |
H2-Eb1 |
histocompatibility 2, class II antigen E beta |
17 |
34305866 |
NM_010382 |
14969 |
84 |
immunological synapse adaptive immune response immune system process peptide antigen assembly with MHC class II protein complex antigen processing and presentation of peptide or polysaccharide antigen via MHC class II protein binding lysosomal membrane lysosomal membrane plasma membrane immune response external side of plasma membrane cell surface membrane antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding polysaccharide binding late endosome membrane late endosome membrane MHC class II receptor activity response to type II interferon peptide antigen binding peptide antigen binding T cell receptor binding CD4 receptor binding MHC class II protein complex MHC class II protein complex MHC class II protein complex positive regulation of immune response positive regulation of T cell activation |
04145 04514 04612 04640 04672 04940 05140 05145 05150 05310 05320 05322 05323 05330 05332 05416 |
| 1454987_a_at |
Hsd17b8 |
hydroxysteroid 17-beta dehydrogenase 8 |
17 |
-34026032 |
AI323545 |
14979 |
32 |
estradiol 17-beta-dehydrogenase [NAD(P)] activity estradiol 17-beta-dehydrogenase [NAD(P)] activity estradiol 17-beta-dehydrogenase [NAD(P)] activity mitochondrion mitochondrial envelope mitochondrial matrix plasma membrane lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process steroid biosynthetic process estrogen biosynthetic process estrogen biosynthetic process androgen metabolic process estrogen metabolic process membrane oxidoreductase activity testosterone dehydrogenase (NAD+) activity protein heterotetramerization NADH binding (3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity oxidoreductase complex |
00140 01100 |
| 1419744_at |
H2-DMb2 |
histocompatibility 2, class II, locus Mb2 |
17 |
34145248, 34143228 |
NM_010388 |
15000 |
24 |
MHC class II protein complex assembly peptide antigen assembly with MHC class II protein complex peptide antigen assembly with MHC class II protein complex protein binding lysosome lysosomal membrane lysosomal membrane lysosomal membrane late endosome multivesicular body endosome membrane membrane antigen processing and presentation antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding MHC class II protein complex binding late endosome membrane late endosome membrane positive regulation of T cell proliferation peptide antigen binding MHC class II protein complex MHC class II protein complex intracellular membrane-bounded organelle positive regulation of immune response positive regulation of T cell activation chaperone cofactor-dependent protein refolding positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell |
04145 04514 04612 04672 04940 05140 05145 05150 05310 05320 05322 05323 05330 05332 05416 |
| 1419297_at |
H2-Oa |
histocompatibility 2, O region alpha locus |
17 |
34092378 |
NM_008206 |
15001 |
33 |
peptide antigen assembly with MHC class II protein complex negative regulation of antigen processing and presentation of peptide antigen via MHC class II lysosomal membrane antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding MHC class II protein complex binding late endosome membrane peptide antigen binding MHC class II protein complex MHC class II protein complex regulation of T cell differentiation positive regulation of immune response positive regulation of T cell activation |
04145 04514 04612 04672 04940 05140 05145 05150 05310 05320 05322 05323 05330 05332 05416 |
| 1440837_at |
H2-Ob |
histocompatibility 2, O region beta locus |
17 |
34238904 |
BG144448 |
15002 |
48 |
peptide antigen assembly with MHC class II protein complex negative regulation of antigen processing and presentation of peptide antigen via MHC class II intracellular anatomical structure lysosome lysosomal membrane antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding MHC class II protein complex binding late endosome membrane peptide antigen binding MHC class II protein complex MHC class II protein complex positive regulation of immune response positive regulation of T cell activation |
04145 04514 04612 04672 04940 05140 05145 05150 05310 05320 05322 05323 05330 05332 05416 |
| 1421596_s_at |
Ifi44l |
interferon-induced protein 44 like |
3 |
-151758736 |
NM_031367 |
15061 |
11 |
cytoplasm immune response immune response defense response to virus |
|
| 1457769_at |
H60a |
histocompatibility 60a |
10 |
|
BB822862 |
15101 |
35 |
positive regulation of immune response to tumor cell plasma membrane external side of plasma membrane membrane positive regulation of type II interferon production positive regulation of natural killer cell activation positive regulation of natural killer cell activation susceptibility to natural killer cell mediated cytotoxicity positive regulation of macrophage activation positive regulation of nitric oxide biosynthetic process natural killer cell lectin-like receptor binding cellular response to organic cyclic compound |
04650 |
| 1455972_x_at |
Hadh |
hydroxyacyl-Coenzyme A dehydrogenase |
3 |
-131233419 |
AV018774 |
15107 |
48 |
3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity protein binding nucleoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation fatty acid beta-oxidation response to xenobiotic stimulus response to activity oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor identical protein binding negative regulation of insulin secretion regulation of insulin secretion NAD+ binding positive regulation of cold-induced thermogenesis |
00062 00071 00280 00310 00380 00650 01100 |
| 1419407_at |
Hc |
hemolytic complement |
2 |
-34983328 |
NM_010406 |
15139 |
336 |
in utero embryonic development neutrophil homeostasis kidney development immune system process endopeptidase inhibitor activity extracellular region membrane attack complex extracellular space inflammatory response complement activation, alternative pathway complement activation, classical pathway positive regulation of vascular endothelial growth factor production negative regulation of macrophage chemotaxis killing of cells of another organism positive regulation of chemokine production glomerulus development innate immune response positive regulation of angiogenesis inflammatory response to wounding |
04610 05020 05150 05322 |
| 1449455_at |
Hck |
hemopoietic cell kinase |
2 |
153108467 |
NM_010407 |
15162 |
132 |
nucleotide binding phosphotyrosine residue binding immune system process protein kinase activity protein tyrosine kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity signaling receptor binding protein binding ATP binding nucleus cytoplasm lysosome Golgi apparatus cytosol cytosol cytoskeleton actin filament plasma membrane caveola focal adhesion protein phosphorylation protein phosphorylation exocytosis phagocytosis inflammatory response transmembrane receptor protein tyrosine kinase signaling pathway positive regulation of cell population proliferation lipid binding regulation of cell shape cytoplasmic side of plasma membrane membrane kinase activity phosphorylation transferase activity peptidyl-tyrosine phosphorylation cell differentiation cytoplasmic vesicle regulation of actin cytoskeleton organization intracellular signal transduction cell projection negative regulation of apoptotic process intracellular membrane-bounded organelle innate immune response innate immune response protein autophosphorylation regulation of phagocytosis defense response to Gram-positive bacterium regulation of DNA-binding transcription factor activity localization anchoring junction regulation of podosome assembly |
04062 04666 |
| 1454713_s_at |
Hdc |
histidine decarboxylase |
2 |
-126593659 |
BG072171 |
15186 |
219 |
histamine metabolic process histamine biosynthetic process histamine biosynthetic process histamine biosynthetic process histidine decarboxylase activity histidine decarboxylase activity histidine decarboxylase activity histidine decarboxylase activity cytoplasm amino acid metabolic process histidine metabolic process histidine catabolic process histidine catabolic process histidine catabolic process histidine catabolic process amino acid binding lyase activity carbon-carbon lyase activity carboxy-lyase activity carboxylic acid metabolic process pyridoxal phosphate binding dendrite catecholamine biosynthetic process identical protein binding neuronal cell body |
00340 01100 |
| 1422018_at |
Hivep2 |
human immunodeficiency virus type I enhancer binding protein 2 |
10 |
13966378, 13966074 |
NM_010437 |
15273 |
45 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm transcription regulator complex DNA-templated transcription regulation of transcription by RNA polymerase II signal transduction positive regulation of transcription by RNA polymerase II metal ion binding |
|
| 1455897_x_at |
Hmgn1 |
high mobility group nucleosomal binding domain 1 |
16 |
-96121587 |
BF464696 |
15312 |
79 |
pyrimidine dimer repair by nucleotide-excision repair chromatin female germ cell nucleus DNA binding chromatin binding chromatin binding protein binding nucleus nucleus nucleoplasm cytoplasm transcription-coupled nucleotide-excision repair chromatin organization chromatin organization regulation of transcription by RNA polymerase II response to UV-B response to UV-C nucleosomal DNA binding regulation of development, heterochronic post-embryonic camera-type eye morphogenesis regulation of epithelial cell proliferation positive regulation of NAD+ ADP-ribosyltransferase activity |
|
| 1436549_a_at |
Hnrnpa1 |
heterogeneous nuclear ribonucleoprotein A1 |
15 |
103240396, 103240396 |
BE685966 |
15382 |
103 |
alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding DNA binding single-stranded DNA binding RNA binding single-stranded RNA binding mRNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding nucleus nucleus nucleoplasm spliceosomal complex cytoplasm mRNA processing RNA splicing positive regulation of gene expression protein domain specific binding RNA strand annealing activity miRNA binding cellular response to potassium ion pre-mRNA binding identical protein binding intracellular non-membrane-bounded organelle synapse synapse positive regulation of action potential mRNA transport telomeric repeat-containing RNA binding catalytic step 2 spliceosome catalytic step 2 spliceosome cellular response to organic substance G-rich strand telomeric DNA binding molecular condensate scaffold activity DNA/DNA annealing activity sequence-specific mRNA binding nucleoplasmic periphery of the nuclear pore complex ribonucleoprotein complex |
03040 |
| 1448881_at |
Hp |
haptoglobin |
8 |
-109575127 |
NM_017370 |
15439 |
97 |
liver development immune system process serine-type endopeptidase activity serine-type endopeptidase activity extracellular region extracellular space extracellular space extracellular space proteolysis acute-phase response Notch signaling pathway response to bacterium antioxidant activity hemoglobin binding haptoglobin-hemoglobin complex spherical high-density lipoprotein particle defense response to bacterium identical protein binding blood microparticle |
|
| 1423944_at |
Hpx |
hemopexin |
7 |
-105591610 |
BC011246 |
15458 |
45 |
positive regulation of immunoglobulin production positive regulation of humoral immune response mediated by circulating immunoglobulin extracellular region extracellular space extracellular space intracellular iron ion homeostasis tyrosine phosphorylation of STAT protein heme transmembrane transporter activity heme transport hemoglobin metabolic process heme binding heme metabolic process heme metabolic process positive regulation of tyrosine phosphorylation of STAT protein metal ion binding regulation of protein metabolic process positive regulation of response to type II interferon type II interferon-mediated signaling pathway positive regulation of type II interferon-mediated signaling pathway |
|
| 1427127_x_at |
Hspa1b |
heat shock protein 1B |
17 |
-34956428 |
M12573 |
15511 |
338 |
G protein-coupled receptor binding protease binding zona pellucida receptor complex signaling receptor binding protein binding ATP binding intracellular anatomical structure nucleus nucleus cytoplasm cytoplasm mitochondrion mitochondrion mitochondrial matrix centrosome centriole cytosol protein folding binding of sperm to zona pellucida response to heat inclusion body aggresome basolateral plasma membrane apical plasma membrane nuclear speck ATP hydrolysis activity ATP hydrolysis activity enzyme binding heat shock protein binding heat shock protein binding ubiquitin protein ligase binding positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein-containing complex protein refolding histone deacetylase binding negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process protein folding chaperone protein folding chaperone protein folding chaperone cell body membrane raft perinuclear region of cytoplasm NF-kappaB binding unfolded protein binding chaperone cofactor-dependent protein refolding C3HC4-type RING finger domain binding ATP-dependent protein disaggregase activity regulation of mitotic spindle assembly ribonucleoprotein complex |
03040 04010 04141 04144 04612 05145 |
| 1424067_at |
Icam1 |
intercellular adhesion molecule 1 |
9 |
21015939 |
BC008626 |
15894 |
604 |
immunological synapse T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell acute inflammatory response to antigenic stimulus T cell antigen processing and presentation positive regulation of cellular extravasation integrin binding integrin binding extracellular space cell adhesion cell adhesion cell adhesion leukocyte cell-cell adhesion leukocyte cell-cell adhesion regulation of cell shape external side of plasma membrane cell surface membrane positive regulation of actin filament polymerization cell adhesion mediated by integrin adhesion of symbiont to host protein-containing complex binding membrane raft positive regulation of nitric oxide biosynthetic process positive regulation of vasoconstriction receptor-mediated virion attachment to host cell positive regulation of peptidyl-tyrosine phosphorylation negative regulation of calcium ion transport establishment of endothelial barrier extracellular exosome positive regulation of ERK1 and ERK2 cascade cellular response to glucose stimulus T cell extravasation establishment of endothelial intestinal barrier establishment of Sertoli cell barrier cell-cell adhesion regulation of ruffle assembly negative regulation of extrinsic apoptotic signaling pathway via death domain receptors cellular response to amyloid-beta positive regulation of leukocyte adhesion to vascular endothelial cell cellular response to leukemia inhibitory factor negative regulation of endothelial cell apoptotic process |
04514 04650 04670 05143 05144 05150 05323 05416 |
| 1448862_at |
Icam2 |
intercellular adhesion molecule 2 |
11 |
-106377655 |
NM_010494 |
15896 |
78 |
uropod integrin binding integrin binding protein binding plasma membrane microvillus cell adhesion cell adhesion membrane cleavage furrow cell projection cell periphery cell-cell adhesion |
04514 04650 |
| 1425895_a_at |
Id1 |
inhibitor of DNA binding 1, HLH protein |
2 |
152736250 |
U43884 |
15901 |
323 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II endothelial cell morphogenesis protein binding nucleus nucleus nucleoplasm cytoplasm centrosome apoptotic process multicellular organism development heart development circadian rhythm positive regulation of gene expression positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression cell differentiation BMP signaling pathway protein destabilization protein destabilization positive regulation of actin filament bundle assembly circadian regulation of gene expression collagen metabolic process identical protein binding negative regulation of apoptotic process negative regulation of DNA binding regulation of MAPK cascade negative regulation of DNA-binding transcription factor activity protein self-association negative regulation of endothelial cell differentiation negative regulation of osteoblast differentiation regulation of angiogenesis negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription response to antibiotic protein dimerization activity rhythmic process positive regulation of epithelial cell proliferation negative regulation of dendrite morphogenesis lung morphogenesis lung vasculature development proteasome binding endothelial cell apoptotic process negative regulation of cold-induced thermogenesis transcription regulator activity transcription regulator inhibitor activity transcription regulator inhibitor activity regulation of vasculature development negative regulation of endothelial cell apoptotic process |
04350 |
| 1435176_a_at |
Id2 |
inhibitor of DNA binding 2 |
12 |
-25093798 |
BF019883 |
15902 |
477 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin euchromatin metanephros development natural killer cell differentiation natural killer cell differentiation thigmotaxis leukocyte differentiation membranous septum morphogenesis bundle of His development protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytosol regulation of transcription by RNA polymerase II multicellular organism development heart development circadian rhythm positive regulation of cell population proliferation adult locomotory behavior entrainment of circadian clock regulation of gene expression positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression negative regulation of gene expression oligodendrocyte development regulation of lipid metabolic process olfactory bulb development cell differentiation B cell differentiation erythrocyte differentiation circadian regulation of gene expression circadian regulation of gene expression protein-containing complex mammary gland epithelial cell proliferation regulation of circadian rhythm entrainment of circadian clock by photoperiod enucleate erythrocyte differentiation negative regulation of DNA binding negative regulation of DNA-binding transcription factor activity transmembrane transporter binding locomotor rhythm negative regulation of B cell differentiation positive regulation of fat cell differentiation positive regulation of erythrocyte differentiation positive regulation of macrophage differentiation regulation of neuron differentiation negative regulation of osteoblast differentiation positive regulation of blood pressure positive regulation of cell cycle negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription protein dimerization activity cell development cell maturation rhythmic process lymph node development Peyer's patch development embryonic digestive tract morphogenesis positive regulation of smooth muscle cell proliferation neuron fate commitment cell morphogenesis involved in neuron differentiation astrocyte differentiation oligodendrocyte differentiation positive regulation of astrocyte differentiation negative regulation of oligodendrocyte differentiation white fat cell differentiation negative regulation of muscle cell differentiation adipose tissue development mammary gland alveolus development epithelial cell differentiation involved in mammary gland alveolus development endodermal digestive tract morphogenesis RNA polymerase II-specific DNA-binding transcription factor binding cellular response to lithium ion dopaminergic neuron differentiation cellular senescence transcription regulator activity transcription regulator inhibitor activity negative regulation of dopaminergic neuron differentiation negative regulation of core promoter binding regulation of G1/S transition of mitotic cell cycle regulation of neural precursor cell proliferation |
04350 |
| 1416630_at |
Id3 |
inhibitor of DNA binding 3 |
4 |
136143821 |
NM_008321 |
15903 |
288 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II metanephros development protein binding nucleus nucleus cytoplasm regulation of DNA replication multicellular organism development central nervous system development heart development muscle organ development circadian rhythm positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression protein domain specific binding cell differentiation epithelial cell differentiation notochord development circadian regulation of gene expression odontogenesis positive regulation of apoptotic process bHLH transcription factor binding negative regulation of DNA-binding transcription factor activity negative regulation of myoblast differentiation negative regulation of osteoblast differentiation negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription protein dimerization activity rhythmic process cellular response to leptomycin B transcription regulator activity transcription regulator inhibitor activity leptomycin B binding |
04350 |
| 1419647_a_at |
Ier3 |
immediate early response 3 |
17 |
35821712 |
NM_133662 |
15937 |
44 |
response to protozoan negative regulation of systemic arterial blood pressure protein binding nucleus nucleus nucleus glycolytic process regulation of DNA repair DNA damage response DNA damage response mitotic G2 DNA damage checkpoint signaling intrinsic apoptotic signaling pathway in response to DNA damage membrane negative regulation of apoptotic process positive regulation of protein catabolic process negative regulation of glycolytic process regulation of nucleocytoplasmic transport negative regulation of inflammatory response negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway regulation of reactive oxygen species metabolic process |
|
| 1418825_at |
Irgm1 |
immunity-related GTPase family M member 1 |
11 |
-48865244 |
NM_008326 |
15944 |
95 |
autophagosome assembly autophagosome assembly Golgi membrane Golgi membrane nucleotide binding autophagosome membrane positive regulation of protein phosphorylation immune system process GTPase activity GTPase activity GTPase activity G protein activity GTP binding phosphatidylinositol-3,4,5-trisphosphate binding mitochondrion lysosome lysosomal membrane endosome late endosome autophagosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus lipid droplet cytosol plasma membrane autophagy defense response defense response lipid binding response to bacterium positive regulation of autophagy positive regulation of autophagy positive regulation of autophagy positive regulation of peptidyl-threonine phosphorylation membrane hydrolase activity protein kinase binding protein-macromolecule adaptor activity cytoplasmic vesicle protein destabilization mitochondrial membrane negative regulation of type I interferon production negative regulation of type I interferon production negative regulation of type II interferon production positive regulation of peptidyl-serine phosphorylation cellular response to interferon-beta defense response to bacterium defense response to bacterium defense response to bacterium cell projection positive regulation of macrophage activation negative regulation of canonical NF-kappaB signal transduction regulation of protein-containing complex assembly phosphatidylinositol-3,4-bisphosphate binding protein serine/threonine kinase activator activity autolysosome innate immune response innate immune response phagocytic vesicle negative regulation of defense response to virus negative regulation of defense response to virus CARD domain binding negative regulation of inflammatory response negative regulation of inflammatory response protein stabilization defense response to Gram-negative bacterium BH3 domain binding positive regulation of type II interferon-mediated signaling pathway positive regulation of type II interferon-mediated signaling pathway regulation of protein complex stability protein lipidation involved in autophagosome assembly CAMKK-AMPK signaling cascade protein-containing complex assembly nucleotide-binding oligomerization domain containing 2 signaling pathway protein targeting to vacuole involved in autophagy cellular response to lipopolysaccharide cellular response to type II interferon positive regulation of protein serine/threonine kinase activity regulation of mitochondrial fission positive regulation of mitochondrial fission autophagosome maturation cellular response to virus negative regulation of cGAS/STING signaling pathway negative regulation of NLRP3 inflammasome complex assembly negative regulation of NLRP3 inflammasome complex assembly positive regulation of autophagosome maturation positive regulation of autophagosome maturation positive regulation of mitophagy positive regulation of mitophagy cardiolipin binding cardiolipin binding negative regulation of hematopoietic stem cell proliferation positive regulation of xenophagy positive regulation of lysosome organization positive regulation of CD4-positive, alpha-beta T cell proliferation |
|
| 1418930_at |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
5 |
-92346638 |
NM_021274 |
15945 |
338 |
positive regulation of leukocyte chemotaxis cytokine activity extracellular region extracellular space extracellular space extracellular space chemotaxis defense response inflammatory response inflammatory response immune response G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway chemokine activity chemokine activity heparin binding positive regulation of cell population proliferation response to bacterium external side of plasma membrane T cell chemotaxis regulation of T cell chemotaxis negative regulation of angiogenesis positive regulation of cell migration neutrophil chemotaxis killing of cells of another organism chemoattractant activity endothelial cell activation regulation of cell population proliferation regulation of apoptotic process CXCR chemokine receptor binding negative regulation of myoblast differentiation CXCR3 chemokine receptor binding positive regulation of release of sequestered calcium ion into cytosol defense response to virus antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide chemokine-mediated signaling pathway chemokine-mediated signaling pathway cellular response to lipopolysaccharide cellular response to lipopolysaccharide positive regulation of monocyte chemotaxis cellular response to interleukin-17 regulation of endothelial tube morphogenesis negative regulation of myoblast fusion positive regulation of T cell migration |
04060 04062 04620 04622 04623 |
| 1419603_at |
Ifi204 |
interferon activated gene 204 |
1 |
-173747293 |
NM_008329 |
15951 |
65 |
negative regulation of transcription by RNA polymerase II activation of innate immune response activation of innate immune response immune system process DNA binding double-stranded DNA binding double-stranded DNA binding double-stranded DNA binding transcription coregulator activity protein binding nucleus nucleoplasm nucleoplasm nucleolus nucleolus nucleolus cytoplasm cytosol cytosol regulation of transcription by RNA polymerase II multicellular organism development transcription factor binding response to bacterium nuclear speck monocyte differentiation ubiquitin protein ligase binding positive regulation of interleukin-1 beta production protein-containing complex cellular response to interferon-alpha cellular response to interferon-beta cellular response to interferon-beta cellular response to glucose starvation nuclear inclusion body intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator identical protein binding intracellular membrane-bounded organelle negative regulation of DNA binding negative regulation of viral genome replication innate immune response positive regulation of osteoblast differentiation negative regulation of gene expression, epigenetic negative regulation of innate immune response negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II inner ear development defense response to virus cellular response to ionizing radiation intrinsic apoptotic signaling pathway by p53 class mediator activation of cysteine-type endopeptidase activity negative regulation of AIM2 inflammasome complex assembly negative regulation of cysteine-type endopeptidase activity |
|
| 1417292_at |
Ifi47 |
interferon gamma inducible protein 47 |
11 |
49087016, 49076586 |
NM_008330 |
15953 |
20 |
GTPase activity endoplasmic reticulum endoplasmic reticulum membrane defense response defense response cellular response to interferon-beta |
|
| 1450783_at |
Ifit1 |
interferon-induced protein with tetratricopeptide repeats 1 |
19 |
34640888 |
NM_008331 |
15957 |
70 |
immune system process RNA binding RNA binding protein binding cytoplasm cytoplasm cytosol cytosol response to virus response to bacterium cellular response to interferon-alpha cellular response to interferon-beta innate immune response defense response to virus defense response to virus |
05160 |
| 1418293_at |
Ifit2 |
interferon-induced protein with tetratricopeptide repeats 2 |
19 |
34551087, 34550693 |
NM_008332 |
15958 |
45 |
immune system process RNA binding cytoplasm endoplasmic reticulum cytosol apoptotic process response to virus response to virus negative regulation of protein binding cellular response to interferon-alpha positive regulation of apoptotic process innate immune response defense response to virus defense response to virus antiviral innate immune response antiviral innate immune response |
|
| 1449025_at |
Ifit3 |
interferon-induced protein with tetratricopeptide repeats 3 |
19 |
34583528 |
NM_010501 |
15959 |
38 |
immune system process protein binding cytoplasm mitochondrion cytosol cytosol negative regulation of cell population proliferation response to virus response to bacterium cellular response to interferon-beta response to stilbenoid identical protein binding negative regulation of apoptotic process innate immune response defense response to virus defense response to virus antiviral innate immune response |
|
| 1451462_a_at |
Ifnar2 |
interferon (alpha and beta) receptor 2 |
16 |
91372782, 91372782, 91372782 |
AF013486 |
15976 |
96 |
type I interferon receptor activity type I interferon receptor activity type I interferon receptor activity extracellular region extracellular space extracellular space extracellular space plasma membrane regulation of transcription by RNA polymerase II receptor signaling pathway via JAK-STAT membrane protein kinase binding cytokine binding type I interferon binding immature T cell proliferation in thymus response to interferon-alpha response to interferon-beta cellular response to interferon-beta interleukin-22 receptor activity defense response to virus type I interferon-mediated signaling pathway type I interferon-mediated signaling pathway |
04060 04380 04620 04630 04650 05160 |
| 1417640_at |
Cd79b |
CD79B antigen |
11 |
-106311340 |
NM_008339 |
15985 |
66 |
adaptive immune response immune system process transmembrane signaling receptor activity protein binding plasma membrane plasma membrane cell surface receptor signaling pathway response to bacterium external side of plasma membrane external side of plasma membrane membrane B cell receptor complex B cell receptor complex B cell differentiation identical protein binding identical protein binding B cell receptor signaling pathway B cell receptor signaling pathway IgM B cell receptor complex |
04662 |
| 1423756_s_at |
Igfbp4 |
insulin-like growth factor binding protein 4 |
11 |
99041243 |
BC019836 |
16010 |
107 |
MAPK cascade regulation of cell growth protein binding insulin-like growth factor binding extracellular region extracellular space extracellular space extracellular space regulation of glucose metabolic process growth factor binding insulin-like growth factor I binding insulin-like growth factor II binding regulation of growth positive regulation of MAPK cascade regulation of insulin-like growth factor receptor signaling pathway positive regulation of insulin-like growth factor receptor signaling pathway type B pancreatic cell proliferation |
|
| 1417933_at |
Igfbp6 |
insulin-like growth factor binding protein 6 |
15 |
102144185 |
NM_008344 |
16012 |
47 |
fibronectin binding extracellular matrix structural constituent insulin-like growth factor binding extracellular region extracellular space extracellular space extracellular space cell migration growth factor binding insulin-like growth factor I binding insulin-like growth factor I binding insulin-like growth factor II binding insulin-like growth factor II binding positive regulation of stress-activated MAPK cascade insulin-like growth factor binary complex identical protein binding positive regulation of MAPK cascade regulation of insulin-like growth factor receptor signaling pathway collagen-containing extracellular matrix |
|
| 1427329_a_at |
Ighm |
immunoglobulin heavy constant mu |
12 |
|
AI326478 |
16019 |
911 |
MAPK cascade adaptive immune response pre-B cell allelic exclusion B cell affinity maturation humoral immune response mediated by circulating immunoglobulin regulation of immunoglobulin production single-stranded DNA binding antigen binding antigen binding transmembrane signaling receptor activity protein binding extracellular region extracellular space extracellular space cytoplasm plasma membrane plasma membrane complement activation, classical pathway external side of plasma membrane cell surface cell surface membrane immunoglobulin mediated immune response peptidyl-tyrosine phosphorylation antibacterial humoral response antibacterial humoral response B cell receptor complex antigen processing and presentation regulation of cell morphogenesis positive regulation of B cell proliferation phosphatidylcholine binding immunoglobulin receptor binding immunoglobulin receptor binding immunoglobulin receptor binding B cell proliferation B cell activation immunoglobulin complex, circulating immunoglobulin complex, circulating identical protein binding peptidoglycan binding positive regulation of MAPK cascade early endosome to late endosome transport innate immune response positive regulation of endocytosis perinuclear region of cytoplasm positive regulation of peptidyl-tyrosine phosphorylation positive regulation of immune response defense response to Gram-negative bacterium defense response to Gram-negative bacterium B cell receptor signaling pathway positive regulation of B cell activation IgM B cell receptor complex pentameric IgM immunoglobulin complex hexameric IgM immunoglobulin complex |
|
| 1450424_a_at |
Il18bp |
interleukin 18 binding protein |
7 |
-102015073 |
AF110803 |
16068 |
33 |
extracellular region extracellular space extracellular space interleukin-18 binding interleukin-18 binding T-helper 1 type immune response T-helper 1 type immune response |
|
| 1430523_s_at |
Iglv1 |
immunoglobulin lambda variable 1 |
16 |
|
AK008145 |
16142 |
57 |
immunoglobulin production extracellular space immune response |
|
| 1425519_a_at |
Cd74 |
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) |
18 |
60803848 |
BC003476 |
16149 |
242 |
prostaglandin biosynthetic process amyloid-beta binding positive regulation of protein phosphorylation positive regulation of cytokine-mediated signaling pathway positive regulation of cytokine-mediated signaling pathway positive regulation of cytokine-mediated signaling pathway adaptive immune response T cell activation involved in immune response immune system process positive regulation of dendritic cell antigen processing and presentation negative regulation of peptide secretion positive regulation of adaptive immune response positive regulation of type 2 immune response positive regulation of type 2 immune response negative regulation of mature B cell apoptotic process cytokine receptor activity cytokine receptor activity cytokine receptor activity protein binding extracellular region extracellular space nucleus cytoplasm cytoplasm lysosome endosome late endosome multivesicular body vacuole endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane plasma membrane plasma membrane intracellular protein transport intracellular protein transport defense response immune response external side of plasma membrane cell surface cell surface positive regulation of gene expression membrane immunoglobulin mediated immune response antigen processing and presentation antigen processing and presentation antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II cytokine binding cytokine binding MHC class II protein complex binding negative regulation of cell migration positive regulation of B cell proliferation positive regulation of prostaglandin biosynthetic process positive regulation of chemokine production positive regulation of interleukin-6 production positive regulation of interleukin-8 production protein-containing complex positive regulation of kinase activity positive regulation of kinase activity response to type II interferon response to type II interferon macrophage migration inhibitory factor signaling pathway macrophage migration inhibitory factor receptor complex macrophage migration inhibitory factor receptor complex NOS2-CD74 complex macrophage migration inhibitory factor binding macrophage migration inhibitory factor binding MHC class II protein binding MHC class II protein binding CD4 receptor binding MHC class II protein complex MHC class II protein binding, via antigen binding groove negative regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction positive regulation of MAPK cascade negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of DNA damage response, signal transduction by p53 class mediator protein folding chaperone positive thymic T cell selection negative thymic T cell selection positive regulation of innate immune response negative regulation of T cell differentiation positive regulation of T cell differentiation positive regulation of monocyte differentiation positive regulation of DNA-templated transcription negative regulation of viral entry into host cell positive regulation of viral entry into host cell positive regulation of fibroblast proliferation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation protein stabilization nitric-oxide synthase binding chaperone cofactor-dependent protein refolding chaperone cofactor-dependent protein refolding positive regulation of macrophage cytokine production positive regulation of macrophage cytokine production protein-containing complex assembly protein trimerization positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade positive regulation of neutrophil chemotaxis negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator positive regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of macrophage migration inhibitory factor signaling pathway |
04612 |
| 1426207_at |
Ikbkb |
inhibitor of kappaB kinase beta |
8 |
-22659204 |
AF088910 |
16150 |
508 |
nucleotide binding B cell homeostasis protein kinase activity protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm cytoplasm cytoplasm cytosol protein phosphorylation canonical NF-kappaB signal transduction canonical NF-kappaB signal transduction I-kappaB phosphorylation positive regulation of cell population proliferation IkappaB kinase activity IkappaB kinase activity IkappaB kinase activity IkappaB kinase complex IkappaB kinase complex IkappaB kinase complex cytoplasmic side of plasma membrane positive regulation of sodium ion transport positive regulation of neuron projection development membrane kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation peptidyl-serine phosphorylation protein kinase binding protein phosphatase binding cortical actin cytoskeleton organization neuron projection development tumor necrosis factor-mediated signaling pathway tumor necrosis factor-mediated signaling pathway tumor necrosis factor-mediated signaling pathway tumor necrosis factor-mediated signaling pathway negative regulation of myosin-light-chain-phosphatase activity CD40 receptor complex regulation of phosphorylation identical protein binding protein homodimerization activity positive regulation of canonical NF-kappaB signal transduction protein-containing complex binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein heterodimerization activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity protein maturation response to cholecystokinin interleukin-1-mediated signaling pathway cellular response to tumor necrosis factor protein localization to plasma membrane scaffold protein binding regulation of establishment of endothelial barrier negative regulation of bicellular tight junction assembly transferrin receptor binding positive regulation of cation channel activity |
04010 04062 04210 04380 04620 04621 04622 04623 04660 04662 04722 04910 04920 04930 05142 05145 05160 05200 05212 05215 05220 05221 05222 |
| 1425454_a_at |
Il12a |
interleukin 12a |
3 |
68691423, 68690643 |
AF128210 |
16159 |
485 |
positive regulation of T cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target cytokine activity cytokine activity interleukin-12 receptor binding protein binding extracellular region extracellular region extracellular space extracellular space cytoplasm endoplasmic reticulum lumen Golgi lumen immune response growth factor activity cell population proliferation cell population proliferation cell surface response to UV-B cell migration endosome lumen response to lipopolysaccharide type II interferon production type II interferon production negative regulation of interleukin-17 production positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of natural killer cell activation positive regulation of mononuclear cell proliferation positive regulation of smooth muscle cell apoptotic process T-helper 1 cell activation interleukin-12-mediated signaling pathway T-helper 1 cell cytokine production T cell proliferation positive regulation of T cell proliferation interleukin-12 beta subunit binding interleukin-12 beta subunit binding positive regulation of tyrosine phosphorylation of STAT protein defense response to protozoan defense response to protozoan interleukin-12 complex interleukin-12 complex interleukin-12 complex interleukin-27 binding positive regulation of T cell differentiation positive regulation of cell adhesion positive regulation of natural killer cell mediated cytotoxicity protein heterodimerization activity negative regulation of smooth muscle cell proliferation positive regulation of lymphocyte proliferation negative regulation of protein secretion positive regulation of NK T cell activation cellular response to lipopolysaccharide extrinsic apoptotic signaling pathway cellular response to virus negative regulation of vascular endothelial growth factor signaling pathway negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis positive regulation of dendritic cell chemotaxis |
04060 04620 04622 04630 04940 05140 05142 05143 05144 05145 05146 05330 |
| 1427164_at |
Il13ra1 |
interleukin 13 receptor, alpha 1 |
X |
36112107 |
BB730912 |
16164 |
69 |
cytokine receptor activity cytokine receptor activity positive regulation of cell population proliferation external side of plasma membrane membrane interleukin-13 receptor activity cytokine-mediated signaling pathway cytokine binding receptor complex |
04060 04630 |
| 1448681_at |
Il15ra |
interleukin 15 receptor, alpha chain |
2 |
11705711, 11705292 |
NM_133836 |
16169 |
160 |
natural killer cell differentiation extracellular region nucleus plasma membrane receptor signaling pathway via JAK-STAT cell surface negative regulation of neuron projection development membrane protein kinase binding cytoplasmic vesicle positive regulation of natural killer cell differentiation interleukin-15-mediated signaling pathway interleukin-15-mediated signaling pathway interleukin-15 receptor activity interleukin-15 receptor activity positive regulation of phagocytosis |
04060 04630 04672 |
| 1417391_a_at |
Il16 |
interleukin 16 |
7 |
-83642818, -83642818, -83642818 |
BC026894 |
16170 |
47 |
cytokine activity cytokine activity protein binding extracellular region extracellular space intracellular anatomical structure nucleus cytoplasm cytosol plasma membrane focal adhesion chemotaxis signal transduction positive regulation of gene expression nuclear speck cytokine-mediated signaling pathway leukocyte chemotaxis leukocyte chemotaxis positive regulation of chemokine production positive regulation of interleukin-1 alpha production positive regulation of interleukin-12 production positive regulation of interleukin-6 production CD4 receptor binding CD4 receptor binding positive regulation of inflammatory response induction of positive chemotaxis induction of positive chemotaxis regulation of calcium ion transport collagen-containing extracellular matrix Flemming body positive regulation of neutrophil activation |
|
| 1417932_at |
Il18 |
interleukin 18 |
9 |
50554699 |
NM_008360 |
16173 |
644 |
angiogenesis angiogenesis response to hypoxia cytokine activity cytokine activity cytokine activity extracellular region extracellular space extracellular space cytoplasm inflammatory response immune response cell population proliferation cell population proliferation extrinsic apoptotic signaling pathway via death domain receptors positive regulation of gene expression positive regulation of macrophage derived foam cell differentiation positive regulation of smooth muscle cell migration apical plasma membrane natural killer cell activation regulation of cell adhesion regulation of cell adhesion sleep sleep type II interferon production interleukin-6 production positive regulation of chemokine production positive regulation of granulocyte macrophage colony-stimulating factor production positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of interleukin-13 production positive regulation of interleukin-17 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of natural killer cell proliferation positive regulation of superoxide anion generation positive regulation of collagen biosynthetic process negative regulation of neutrophil apoptotic process interleukin-18-mediated signaling pathway interleukin-18-mediated signaling pathway T-helper 1 cell cytokine production T-helper 1 cell cytokine production T-helper 1 type immune response T-helper 1 type immune response positive regulation of activated T cell proliferation positive regulation of activated T cell proliferation neutrophil activation natural killer cell mediated cytotoxicity positive regulation of tyrosine phosphorylation of STAT protein cholesterol homeostasis positive regulation of apoptotic process positive regulation of vascular permeability positive regulation of neuron apoptotic process interleukin-18 receptor binding positive regulation of T-helper 2 cell differentiation negative regulation of myoblast differentiation positive regulation of transcription by RNA polymerase II receptor ligand activity positive regulation of smooth muscle cell proliferation positive regulation of inflammatory response negative regulation of peptidyl-tyrosine phosphorylation defense response to Gram-positive bacterium detection of mechanical stimulus involved in sensory perception of pain positive regulation of NF-kappaB transcription factor activity positive regulation of NK T cell proliferation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction establishment of skin barrier triglyceride homeostasis cellular response to peptide hormone stimulus positive regulation of cold-induced thermogenesis positive regulation of non-canonical NF-kappaB signal transduction positive regulation of male germ cell proliferation positive regulation of hepatocyte proliferation positive regulation of blood vessel remodeling positive regulation of T-helper 1 cell cytokine production |
04060 04621 04623 05143 05144 05323 |
| 1421291_at |
Il18rap |
interleukin 18 receptor accessory protein |
1 |
40515361 |
NM_010553 |
16174 |
17 |
interleukin-1 receptor activity plasma membrane inflammatory response signal transduction cell population proliferation coreceptor activity membrane hydrolase activity type II interferon production interleukin-6 production interleukin-18-mediated signaling pathway interleukin-18-mediated signaling pathway interleukin-18-mediated signaling pathway T-helper 1 cell cytokine production interleukin-18 receptor activity interleukin-18 receptor activity neutrophil activation interleukin-18 receptor complex positive regulation of natural killer cell mediated cytotoxicity NADP+ nucleosidase activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity NAD+ nucleotidase, cyclic ADP-ribose generating cellular response to interleukin-18 |
04060 |
| 1419532_at |
Il1r2 |
interleukin 1 receptor, type II |
1 |
40084713, 40086092 |
NM_010555 |
16178 |
56 |
interleukin-1 receptor activity interleukin-1 receptor activity interleukin-1, type II, blocking receptor activity extracellular region cytoplasm plasma membrane negative regulation of protein processing membrane protein processing interleukin-1 binding interleukin-1 binding negative regulation of interleukin-1 alpha production negative regulation of cytokine production involved in inflammatory response negative regulation of interleukin-1-mediated signaling pathway |
04010 04060 04640 05146 |
| 1421844_at |
Il1rap |
interleukin 1 receptor accessory protein |
16 |
26581704, 26581704, 26581704, 26581704 |
BE285634 |
16180 |
54 |
interleukin-33 receptor activity immune system process interleukin-1 receptor activity interleukin-1 receptor activity interleukin-1 receptor binding interleukin-1 receptor binding protein binding extracellular region plasma membrane inflammatory response signal transduction coreceptor activity membrane hydrolase activity cytokine-mediated signaling pathway interleukin-2 production positive regulation of interleukin-13 production positive regulation of interleukin-4 production positive regulation of interleukin-5 production positive regulation of interleukin-6 production protein-containing complex interleukin-33-mediated signaling pathway interleukin-33-mediated signaling pathway innate immune response synapse synapse NADP+ nucleosidase activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of synapse assembly NAD+ nucleotidase, cyclic ADP-ribose generating interleukin-1-mediated signaling pathway glutamatergic synapse glutamatergic synapse regulation of postsynaptic density assembly regulation of postsynaptic density assembly trans-synaptic signaling by trans-synaptic complex trans-synaptic signaling by trans-synaptic complex synaptic membrane adhesion synaptic membrane adhesion regulation of presynapse assembly regulation of presynapse assembly |
04060 04210 |
| 1451798_at |
Il1rn |
interleukin 1 receptor antagonist |
2 |
24345370, 24345290, 24336859 |
M57525 |
16181 |
200 |
fever generation inflammatory response to antigenic stimulus cytokine activity interleukin-1 receptor binding interleukin-1, type I receptor binding interleukin-1, type II receptor binding interleukin-1 receptor antagonist activity interleukin-1 receptor antagonist activity extracellular region extracellular space extracellular space nucleoplasm cytoplasm centrosome cytosol lipid metabolic process acute-phase response inflammatory response immune response memory negative regulation of glutamate secretion insulin secretion negative regulation of cell migration vesicle negative regulation of heterotypic cell-cell adhesion negative regulation of apoptotic process interleukin-1 type I receptor antagonist activity interleukin-1 type II receptor antagonist activity negative regulation of membrane potential response to glucocorticoid negative regulation of interleukin-1-mediated signaling pathway negative regulation of interleukin-1-mediated signaling pathway |
|
| 1416295_a_at |
Il2rg |
interleukin 2 receptor, gamma chain |
X |
-101264384 |
L20048 |
16186 |
822 |
mature B cell differentiation CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation cytokine receptor activity cytokine receptor activity nucleoplasm endoplasmic reticulum plasma membrane plasma membrane external side of plasma membrane external side of plasma membrane cell surface gene expression regulation of gene expression positive regulation of gene expression coreceptor activity membrane cytokine-mediated signaling pathway cytokine binding interleukin-2 binding lymphocyte differentiation B cell differentiation positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation T cell differentiation in thymus positive regulation of T cell differentiation in thymus interleukin-15-mediated signaling pathway interleukin-2-mediated signaling pathway interleukin-9-mediated signaling pathway interleukin-15 receptor activity receptor complex positive regulation of B cell differentiation positive regulation of phagocytosis |
04060 04144 04630 05340 |
| 1452843_at |
Il6st |
interleukin 6 signal transducer |
13 |
112464069 |
AK017211 |
16195 |
319 |
cytokine receptor activity cytokine receptor activity ciliary neurotrophic factor receptor activity interleukin-6 receptor activity interleukin-6 receptor activity interleukin-11 receptor activity leukemia inhibitory factor receptor activity oncostatin-M receptor activity ciliary neurotrophic factor receptor binding interleukin-6 receptor binding protein binding extracellular space plasma membrane interleukin-6 receptor complex oncostatin-M receptor complex glycogen metabolic process triglyceride mobilization signal transduction positive regulation of cell population proliferation positive regulation of cell population proliferation regulation of Notch signaling pathway external side of plasma membrane external side of plasma membrane positive regulation of smooth muscle cell migration coreceptor activity membrane cytokine-mediated signaling pathway cytokine-mediated signaling pathway cytokine-mediated signaling pathway growth factor binding cytokine binding interleukin-11 binding interleukin-6 binding interleukin-6 binding protein tyrosine kinase activator activity dendrite neuronal cell body membrane response to cytokine interleukin-11-mediated signaling pathway oncostatin-M-mediated signaling pathway positive regulation of T cell proliferation positive regulation of tyrosine phosphorylation of STAT protein identical protein binding neuronal cell body receptor complex negative regulation of neuron apoptotic process cell body membrane raft positive regulation of osteoblast differentiation positive regulation of Notch signaling pathway positive regulation of Notch signaling pathway positive regulation of astrocyte differentiation leukemia inhibitory factor signaling pathway negative regulation of cytosolic calcium ion concentration intestinal epithelial cell development intestinal epithelial cell development interleukin-6-mediated signaling pathway interleukin-6-mediated signaling pathway negative regulation of interleukin-6-mediated signaling pathway interleukin-27-mediated signaling pathway ciliary neurotrophic factor receptor complex ciliary neurotrophic factor-mediated signaling pathway scaffold protein binding |
04060 04630 |
| 1448575_at |
Il7r |
interleukin 7 receptor |
15 |
-9506158 |
AI573431 |
16197 |
391 |
cell morphogenesis B cell homeostasis T cell mediated cytotoxicity negative regulation of T cell mediated cytotoxicity immunoglobulin production cytokine receptor activity cytokine receptor activity nucleoplasm cytosol plasma membrane plasma membrane positive regulation of cell population proliferation regulation of cell size regulation of cell size external side of plasma membrane external side of plasma membrane gene expression positive regulation of gene expression membrane cytokine-mediated signaling pathway hemopoiesis T cell differentiation T cell differentiation T cell differentiation in thymus positive regulation of T cell differentiation in thymus B cell proliferation B cell proliferation T cell homeostasis positive regulation of receptor signaling pathway via JAK-STAT lymph node development defense response to Gram-positive bacterium negative regulation of T cell apoptotic process positive regulation of receptor signaling pathway via STAT |
04060 04630 04640 05340 |
| 1460669_at |
Ilf3 |
interleukin enhancer binding factor 3 |
9 |
21367870, 21368531, 21367870 |
NM_010561 |
16201 |
75 |
virus receptor activity DNA binding DNA binding RNA binding double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding nucleus nucleus nucleoplasm nucleolus cytoplasm cytoplasm mitochondrion protein phosphorylation protein phosphorylation protein methylation negative regulation of translation enzyme binding mRNA 3'-UTR AU-rich region binding negative regulation of viral genome replication negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription defense response to virus ribonucleoprotein complex |
|
| 1449988_at |
Gimap1 |
GTPase, IMAP family member 1 |
6 |
48739046 |
NM_008376 |
16205 |
23 |
nucleotide binding GTP binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum Golgi apparatus membrane B cell differentiation CD4-positive, alpha-beta T cell differentiation CD8-positive, alpha-beta T cell differentiation |
|
| 1460432_a_at |
Eif3e |
eukaryotic translation initiation factor 3, subunit E |
15 |
-43250039 |
AK002576 |
16341 |
49 |
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay translation initiation factor activity translation initiation factor activity nucleus nucleus cytoplasm cytosol eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex translation translational initiation translational initiation translational initiation intracellular calcium ion homeostasis postsynaptic density postsynaptic density PML body transmembrane transporter binding positive regulation of translation positive regulation of intracellular protein transport positive regulation of mRNA binding |
03013 05160 |
| 1448436_a_at |
Irf1 |
interferon regulatory factor 1 |
11 |
53770013, 53770013, 53770472 |
NM_008390 |
16362 |
333 |
chromatin transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific immune system process immune system process regulation of adaptive immune response DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleus cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II apoptotic process canonical NF-kappaB signal transduction regulation of gene expression positive regulation of type I interferon production positive regulation of interferon-beta production positive regulation of interleukin-12 production positive regulation of interleukin-12 production positive regulation of natural killer cell differentiation regulation of MyD88-dependent toll-like receptor signaling pathway toll-like receptor 3 signaling pathway cellular response to interferon-beta negative regulation of tyrosine phosphorylation of STAT protein positive regulation of apoptotic process CD8-positive, alpha-beta T cell differentiation sequence-specific DNA binding sequence-specific DNA binding innate immune response regulation of innate immune response negative regulation of regulatory T cell differentiation positive regulation of T-helper 1 cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II defense response to virus defense response to virus regulation of cell cycle type II interferon-mediated signaling pathway response to growth hormone cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to peptide hormone stimulus regulation of CD8-positive, alpha-beta T cell proliferation |
05160 |
| 1421173_at |
Irf4 |
interferon regulatory factor 4 |
13 |
30749232 |
U34307 |
16364 |
301 |
nucleosome transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific immune system process DNA binding DNA-binding transcription factor activity transcription coactivator activity protein binding nucleus nucleus nucleoplasm cytosol chromatin remodeling regulation of DNA-templated transcription regulation of transcription by RNA polymerase II positive regulation of interleukin-10 production positive regulation of interleukin-13 production positive regulation of interleukin-2 production positive regulation of interleukin-4 production negative regulation of toll-like receptor signaling pathway defense response to protozoan myeloid dendritic cell differentiation positive regulation of DNA binding sequence-specific DNA binding positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II T-helper 17 cell lineage commitment positive regulation of cold-induced thermogenesis sequence-specific double-stranded DNA binding |
|
| 1427381_at |
Acod1 |
aconitate decarboxylase 1 |
14 |
103047011 |
L38281 |
16365 |
73 |
immune system process positive regulation of antimicrobial humoral response positive regulation of antimicrobial humoral response mitochondrion mitochondrion defense response defense response defense response inflammatory response embryo implantation response to bacterium lyase activity negative regulation of NF-kappaB transcription factor activity negative regulation of type I interferon production response to lipopolysaccharide negative regulation of toll-like receptor 2 signaling pathway negative regulation of toll-like receptor 4 signaling pathway cellular response to interferon-beta protein homodimerization activity protein homodimerization activity innate immune response negative regulation of innate immune response aconitate decarboxylase activity aconitate decarboxylase activity aconitate decarboxylase activity aconitate decarboxylase activity negative regulation of inflammatory response defense response to virus cellular response to molecule of bacterial origin cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to type II interferon cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to progesterone stimulus tolerance induction to lipopolysaccharide tolerance induction to lipopolysaccharide positive regulation of reactive oxygen species metabolic process |
|
| 1422046_at |
Itgam |
integrin alpha M |
7 |
128062639 |
NM_008401 |
16409 |
576 |
microglial cell activation neutrophil apoptotic process opsonin binding opsonin binding complement component C3b binding complement receptor mediated signaling pathway leukocyte migration involved in inflammatory response integrin binding protein binding extracellular space nucleus plasma membrane plasma membrane receptor-mediated endocytosis phagocytosis phagocytosis, engulfment cell adhesion cell adhesion leukocyte cell-cell adhesion cell-matrix adhesion integrin-mediated signaling pathway heparin binding integrin complex external side of plasma membrane external side of plasma membrane cell surface cell surface microglia development membrane neutrophil chemotaxis forebrain development heat shock protein binding positive regulation of superoxide anion generation positive regulation of superoxide anion generation positive regulation of superoxide anion generation cell adhesion mediated by integrin integrin alphaM-beta2 complex cargo receptor activity cargo receptor activity positive regulation of neutrophil degranulation heparan sulfate proteoglycan binding plasma membrane raft cellular extravasation negative regulation of dopamine metabolic process activated T cell proliferation positive regulation of mast cell differentiation leukocyte adhesion to vascular endothelial cell positive regulation of protein targeting to membrane amyloid-beta clearance amyloid-beta clearance cell-cell adhesion cell-cell adhesion complement-mediated synapse pruning vertebrate eye-specific patterning positive regulation of microglial cell mediated cytotoxicity positive regulation of prostaglandin-E synthase activity |
04145 04514 04640 04670 04810 05140 05146 05150 |
| 1449829_at |
Itgb2l |
integrin beta 2-like |
16 |
-96422297 |
NM_008405 |
16415 |
19 |
amyloid-beta binding leukocyte migration involved in inflammatory response integrin binding plasma membrane focal adhesion inflammatory response cell adhesion leukocyte cell-cell adhesion leukocyte cell-cell adhesion cell-matrix adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin-mediated signaling pathway integrin complex cell surface cell surface membrane protein kinase binding protein kinase binding secretory granule ICAM-3 receptor activity neutrophil chemotaxis neutrophil chemotaxis heat shock protein binding positive regulation of superoxide anion generation cell adhesion mediated by integrin heterotypic cell-cell adhesion integrin alphaL-beta2 complex receptor clustering positive regulation of neutrophil degranulation endothelial cell migration plasma membrane raft protein-containing complex binding cellular extravasation positive regulation of nitric oxide biosynthetic process positive regulation of angiogenesis regulation of peptidyl-tyrosine phosphorylation cell adhesion molecule binding cell-cell adhesion neutrophil migration |
04145 04514 04650 04670 04810 05140 05144 05146 05150 05323 05416 |
| 1431808_a_at |
Itih4 |
inter alpha-trypsin inhibitor, heavy chain 4 |
14 |
30886475 |
AK004893 |
16427 |
30 |
serine-type endopeptidase inhibitor activity protein binding extracellular region extracellular space cytoplasm plasma membrane acute-phase response negative regulation of peptidase activity hyaluronan metabolic process peptidase inhibitor activity collagen-containing extracellular matrix |
|
| 1417171_at |
Itk |
IL2 inducible T cell kinase |
11 |
-46325147, -46344477 |
NM_010583 |
16428 |
153 |
nucleotide binding positive regulation of cytokine production NK T cell differentiation NK T cell differentiation NK T cell differentiation adaptive immune response adaptive immune response immune system process protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding nucleus cytoplasm cytosol cytosol plasma membrane cell-cell junction protein phosphorylation protein phosphorylation activation of phospholipase C activity kinase activity phosphorylation transferase activity type II interferon production type II interferon production interleukin-4 production interleukin-4 production intracellular signal transduction gamma-delta T cell activation metal ion binding T cell receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway |
04062 04660 04670 |
| 1423608_at |
Itm2a |
integral membrane protein 2A |
X |
-107397194 |
BI966443 |
16431 |
31 |
amyloid-beta binding plasma cell differentiation immunoglobulin production Golgi apparatus plasma membrane membrane negative regulation of amyloid precursor protein biosynthetic process |
|
| 1460203_at |
Itpr1 |
inositol 1,4,5-trisphosphate receptor 1 |
6 |
108213095 |
NM_010585 |
16438 |
306 |
cell morphogenesis response to hypoxia response to hypoxia monoatomic ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium ion binding protein binding nuclear envelope nuclear envelope nuclear inner membrane nucleolus cytoplasm endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane plasma membrane calcineurin complex monoatomic ion transport calcium ion transport apoptotic process phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway post-embryonic development positive regulation of neuron projection development postsynaptic density calcium-release channel activity membrane sarcoplasmic reticulum sarcoplasmic reticulum sarcoplasmic reticulum calcium-mediated signaling calcium channel inhibitor activity protein phosphatase binding protein domain specific binding dendrite secretory granule membrane smooth endoplasmic reticulum membrane platelet dense granule membrane platelet dense tubular network cytoplasmic vesicle positive regulation of insulin secretion positive regulation of insulin secretion endoplasmic reticulum calcium ion homeostasis protein-containing complex protein-containing complex monoatomic ion transmembrane transport phosphatidylinositol binding phosphatidylinositol binding epithelial fluid transport identical protein binding neuronal cell body positive regulation of apoptotic process negative regulation of apoptotic process transmembrane transporter binding protein-containing complex binding synapse perinuclear region of cytoplasm negative regulation of calcium-mediated signaling voluntary musculoskeletal movement release of sequestered calcium ion into cytosol release of sequestered calcium ion into cytosol release of sequestered calcium ion into cytosol positive regulation of calcium ion transport transmembrane transport intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress calcium ion transmembrane transport inositol 1,4,5 trisphosphate binding inositol 1,4,5 trisphosphate binding cellular response to cAMP synaptic membrane liver regeneration Schaffer collateral - CA1 synapse Schaffer collateral - CA1 synapse Schaffer collateral - CA1 synapse inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels presynapse postsynapse GABA-ergic synapse ion channel modulating, G protein-coupled receptor signaling pathway ion channel modulating, G protein-coupled receptor signaling pathway regulation of postsynaptic cytosolic calcium ion concentration ligand-gated ion channel signaling pathway ligand-gated ion channel signaling pathway positive regulation of hepatocyte proliferation |
04020 04070 04114 04270 04540 04720 04730 04912 04970 04971 04972 05010 05016 |
| 1417297_at |
Itpr3 |
inositol 1,4,5-triphosphate receptor 3 |
17 |
27057303 |
NM_080553 |
16440 |
192 |
inositol hexakisphosphate binding monoatomic ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium ion binding calcium ion binding protein binding nucleus nuclear envelope nuclear outer membrane nucleoplasm nucleolus cytoplasm endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane plasma membrane plasma membrane brush border monoatomic ion transport calcium ion transport G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration memory calcium-release channel activity membrane apical plasma membrane sarcoplasmic reticulum dendrite secretory granule membrane monoatomic ion transmembrane transport phosphatidylinositol binding phosphatidylinositol binding identical protein binding neuronal cell body receptor complex inositol 1,3,4,5 tetrakisphosphate binding protein-containing complex binding apical part of cell perinuclear region of cytoplasm sensory perception of bitter taste sensory perception of sweet taste sensory perception of umami taste release of sequestered calcium ion into cytosol response to calcium ion calcium ion homeostasis transmembrane transport long-term synaptic potentiation calcium ion transmembrane transport inositol 1,4,5 trisphosphate binding inositol 1,4,5 trisphosphate binding cellular response to cAMP cytoplasmic side of endoplasmic reticulum membrane presynapse |
04020 04070 04114 04270 04540 04720 04730 04742 04912 04970 04971 04972 05010 |
| 1417409_at |
Jun |
jun proto-oncogene |
4 |
-95049035 |
NM_010591 |
16476 |
764 |
negative regulation of transcription by RNA polymerase II chromatin euchromatin transcription cis-regulatory region binding transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific angiogenesis angiogenesis microglial cell activation release of cytochrome c from mitochondria liver development positive regulation of endothelial cell proliferation outflow tract morphogenesis DNA binding chromatin binding double-stranded DNA binding DNA-binding transcription factor activity GTPase activator activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex transcription regulator complex transcription regulator complex cytosol DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II apoptotic process transforming growth factor beta receptor signaling pathway learning transcription factor binding cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation response to xenobiotic stimulus positive regulation of epithelial cell migration transcription repressor complex release from viral latency enzyme binding monocyte differentiation axon regeneration ubiquitin protein ligase binding negative regulation of protein autophosphorylation protein-containing complex cellular response to reactive oxygen species response to endoplasmic reticulum stress leading edge cell differentiation cAMP response element binding transcription factor AP-1 complex transcription factor AP-1 complex response to muscle stretch regulation of cell population proliferation identical protein binding positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of DNA binding negative regulation of neuron apoptotic process positive regulation of neuron apoptotic process sequence-specific DNA binding negative regulation by host of viral transcription positive regulation by host of viral transcription ubiquitin-like protein ligase binding protein-containing complex binding positive regulation of monocyte differentiation positive regulation of DNA replication negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of fibroblast proliferation positive regulation of fibroblast proliferation positive regulation of smooth muscle cell proliferation cellular response to potassium ion starvation regulation of cell cycle regulation of cell cycle membrane depolarization SMAD protein signal transduction eyelid development in camera-type eye RNA polymerase II-specific DNA-binding transcription factor binding positive regulation of ERK1 and ERK2 cascade R-SMAD binding cellular response to cadmium ion cellular response to calcium ion HMG box domain binding cellular response to anisomycin RNA polymerase II transcription regulator complex general transcription initiation factor binding positive regulation of miRNA transcription positive regulation of vascular associated smooth muscle cell proliferation sequence-specific double-stranded DNA binding positive regulation of DNA-templated transcription initiation |
04010 04012 04310 04380 04510 04620 04660 04662 04722 04912 05140 05142 05200 05210 05211 05323 |
| 1435772_at |
Kif21b |
kinesin family member 21B |
1 |
136131389 |
AV122249 |
16565 |
37 |
nucleotide binding microtubule motor activity microtubule motor activity ATP binding cytoplasm cytoskeleton kinesin complex microtubule microtubule microtubule-based movement microtubule-based movement brain development microtubule binding microtubule binding ATP hydrolysis activity corpus callosum development cytoplasmic vesicle cell projection |
|
| 1416021_a_at |
Fabp5 |
fatty acid binding protein 5, epidermal |
3 |
10012584 |
BC002008 |
16592 |
150 |
retinoic acid binding long-chain fatty acid transporter activity fatty acid binding fatty acid binding extracellular region extracellular space nucleus nucleus nucleus cytoplasm cytoplasm cytosol glucose metabolic process lipid metabolic process phosphatidylcholine biosynthetic process lipid transport lipid binding negative regulation of glucose transmembrane transport postsynaptic density fatty acid transport regulation of prostaglandin biosynthetic process positive regulation of peroxisome proliferator activated receptor signaling pathway glucose homeostasis identical protein binding synapse regulation of sensory perception of pain regulation of retrograde trans-synaptic signaling by endocanabinoid positive regulation of cold-induced thermogenesis |
03320 |
| 1456341_a_at |
Klf9 |
Kruppel-like transcription factor 9 |
19 |
23141225 |
AV354744 |
16601 |
96 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm cytosol plasma membrane regulation of DNA-templated transcription regulation of transcription by RNA polymerase II embryo implantation negative regulation of keratinocyte proliferation positive regulation of transcription by RNA polymerase II metal ion binding rhythmic process progesterone receptor signaling pathway cellular response to cortisol stimulus |
|
| 1421304_at |
Klra2 |
killer cell lectin-like receptor, subfamily A, member 2 |
6 |
-131219234 |
NM_008462 |
16633 |
25 |
plasma membrane cell adhesion membrane carbohydrate binding |
|
| 1458802_at |
Hivep3 |
human immunodeficiency virus type I enhancer binding protein 3 |
4 |
119814677 |
BB164127 |
16656 |
46 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus nucleus cytoplasm cytosol regulation of transcription by RNA polymerase II skeletal muscle cell differentiation positive regulation of DNA-templated transcription metal ion binding |
|
| 1451716_at |
Mafb |
MAF bZIP transcription factor B |
2 |
-160363676 |
AW412521 |
16658 |
292 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II segment specification respiratory gaseous exchange by respiratory system gene expression protein processing rhombomere 5 development rhombomere 6 development abducens nerve formation keratinocyte differentiation T cell differentiation in thymus brain segmentation inner ear morphogenesis identical protein binding sequence-specific DNA binding protein-containing complex binding regulation of myeloid cell differentiation negative regulation of erythrocyte differentiation negative regulation of osteoclast differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II thymus development RNA polymerase II transcription regulator complex cornified envelope assembly sequence-specific double-stranded DNA binding |
|
| 1455434_a_at |
Ktn1 |
kinectin 1 |
14 |
47663755, 47649310 |
BF162017 |
16709 |
36 |
endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane microtubule-based movement protein transport membrane kinesin binding |
|
| 1433939_at |
Aff3 |
AF4/FMR2 family, member 3 |
1 |
-38175990 |
BQ177036 |
16764 |
39 |
DNA binding double-stranded DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity nucleus nucleus nucleoplasm cytosol DNA-templated transcription regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of gene expression regulation of gene expression nuclear body super elongation complex response to tumor necrosis factor embryonic hindlimb morphogenesis embryonic hindlimb morphogenesis |
|
| 1428094_at |
Lamp2 |
lysosomal-associated membrane protein 2 |
X |
-38405048, -38419502, -38399646 |
BB390704 |
16784 |
183 |
autophagosome membrane protein binding extracellular space lysosome lysosome lysosomal membrane lysosomal membrane lysosomal membrane endosome late endosome late endosome trans-Golgi network plasma membrane plasma membrane protein targeting autophagy lysosomal lumen acidification ion channel inhibitor activity cellular response to starvation cellular response to starvation membrane enzyme binding protein domain specific binding protein catabolic process phagocytic vesicle membrane platelet dense granule membrane negative regulation of protein-containing complex assembly cytoplasmic vesicle regulation of protein stability late endosome membrane late endosome membrane late endosome membrane signaling adaptor activity intracellular membrane-bounded organelle autolysosome membrane raft muscle cell cellular homeostasis perinuclear region of cytoplasm protein stabilization chaperone-mediated autophagy chaperone-mediated autophagy chaperone-mediated autophagy protein targeting to lysosome involved in chaperone-mediated autophagy protein targeting to lysosome involved in chaperone-mediated autophagy protein targeting to lysosome involved in chaperone-mediated autophagy chaperone-mediated autophagy translocation complex extracellular exosome autophagosome maturation autophagosome maturation negative regulation of NLRP3 inflammasome complex assembly lysosomal protein catabolic process lysosomal matrix |
04142 04145 |
| 1460651_at |
Lat |
linker for activation of T cells |
7 |
-126363827 |
AF036907 |
16797 |
158 |
immunological synapse immunological synapse immunological synapse adaptive immune response lymphocyte homeostasis immune system process protein binding Golgi apparatus plasma membrane plasma membrane cell-cell junction inflammatory response inflammatory response immune response immune response cellular defense response signal transduction transmembrane receptor protein tyrosine kinase signaling pathway integrin-mediated signaling pathway Ras protein signal transduction COP9 signalosome gene expression membrane calcium-mediated signaling protein kinase binding protein kinase binding signaling receptor complex adaptor activity intracellular signal transduction intracellular signal transduction mast cell degranulation positive regulation of protein kinase activity homeostasis of number of cells T cell receptor signaling pathway regulation of T cell activation regulation of T cell activation |
04650 04660 04664 04666 |
| 1421164_a_at |
Arhgef1 |
Rho guanine nucleotide exchange factor 1 |
7 |
24902985, 24904345 |
NM_008488 |
16801 |
62 |
G protein-coupled receptor binding G protein-coupled receptor binding guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity GTPase activator activity protein binding cytoplasm cytoplasm cytosol plasma membrane microtubule depolymerization G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway membrane |
04270 04810 |
| 1448550_at |
Lbp |
lipopolysaccharide binding protein |
2 |
158306492 |
NM_008489 |
16803 |
65 |
lipopolysaccharide binding lipopolysaccharide binding lipopolysaccharide binding leukocyte chemotaxis involved in inflammatory response macrophage activation involved in immune response macrophage activation involved in immune response macrophage activation involved in immune response immune system process cell surface pattern recognition receptor signaling pathway signaling receptor binding extracellular region extracellular space extracellular space extracellular space lipid transport acute-phase response acute-phase response lipid binding cell surface cell surface coreceptor activity lipopolysaccharide transport membrane neutrophil chemotaxis lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway detection of molecule of bacterial origin response to lipopolysaccharide response to lipopolysaccharide tumor necrosis factor production negative regulation of tumor necrosis factor production positive regulation of chemokine production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of toll-like receptor 4 signaling pathway defense response to bacterium positive regulation of macrophage activation positive regulation of macrophage activation innate immune response innate immune response defense response to Gram-negative bacterium defense response to Gram-negative bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium positive regulation of phagocytosis, engulfment positive regulation of respiratory burst involved in inflammatory response lipoteichoic acid binding cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipoteichoic acid lipopeptide binding positive regulation of neutrophil chemotaxis regulation of membrane permeability |
04620 |
| 1425396_a_at |
Lck |
lymphocyte protein tyrosine kinase |
4 |
-129548343, -129548343 |
BC011474 |
16818 |
302 |
nucleotide binding pericentriolar material immunological synapse phosphotyrosine residue binding antigen binding protein kinase activity protein tyrosine kinase activity protein tyrosine kinase activity protein tyrosine kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein serine/threonine phosphatase activity signaling receptor binding protein binding ATP binding cytoplasm cytosol plasma membrane plasma membrane cell-cell junction protein phosphorylation protein phosphorylation protein phosphorylation activation of cysteine-type endopeptidase activity involved in apoptotic process cell surface receptor signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway response to xenobiotic stimulus response to mechanical stimulus response to metal ion positive regulation of gene expression phospholipase activator activity membrane kinase activity phosphorylation transferase activity peptidyl-tyrosine phosphorylation peptidyl-tyrosine phosphorylation protein kinase binding protein phosphatase binding protein phosphatase binding endocytic vesicle T cell differentiation T cell differentiation positive regulation of heterotypic cell-cell adhesion intracellular signal transduction peptidyl-tyrosine autophosphorylation Fc-gamma receptor signaling pathway SH2 domain binding gamma-delta T cell differentiation positive regulation of tyrosine phosphorylation of STAT protein response to hydrogen peroxide T cell receptor binding CD4 receptor binding CD4 receptor binding CD8 receptor binding identical protein binding phospholipase binding phosphatidylinositol 3-kinase binding protein-containing complex binding innate immune response membrane raft positive regulation of gamma-delta T cell differentiation regulation of regulatory T cell differentiation protein autophosphorylation B cell receptor signaling pathway B cell receptor signaling pathway regulation of T cell receptor signaling pathway positive regulation of T cell activation ATPase binding release of sequestered calcium ion into cytosol positive regulation of uterine smooth muscle contraction glutamatergic synapse postsynaptic specialization, intracellular component positive regulation of leukocyte cell-cell adhesion protein antigen binding positive regulation of intrinsic apoptotic signaling pathway |
04380 04650 04660 05340 |
| 1427747_a_at |
Lcn2 |
lipocalin 2 |
2 |
-32384636 |
X14607 |
16819 |
375 |
protease binding immune system process iron ion binding iron ion binding protein binding extracellular region extracellular region extracellular space extracellular space extracellular space extracellular space cytosol monoatomic ion transport iron ion transport apoptotic process short-term memory long-term memory response to xenobiotic stimulus response to virus response to bacterium response to herbicide positive regulation of endothelial cell migration positive regulation of gene expression siderophore transport siderophore transport positive regulation of cell projection organization cytoplasmic vesicle small molecule binding defense response to bacterium identical protein binding positive regulation of apoptotic process positive regulation of neuron apoptotic process innate immune response cellular response to hydrogen peroxide extrinsic apoptotic signaling pathway in absence of ligand positive regulation of hippocampal neuron apoptotic process negative regulation of hippocampal neuron apoptotic process positive regulation of cold-induced thermogenesis iron ion sequestering activity positive regulation of reactive oxygen species biosynthetic process enterobactin binding positive regulation of iron ion import across plasma membrane positive regulation of endothelial tube morphogenesis positive regulation of reactive oxygen species metabolic process |
|
| 1452024_a_at |
Ldb1 |
LIM domain binding 1 |
19 |
-46032589, -46032589, -46032589 |
AF030333 |
16825 |
137 |
negative regulation of transcription by RNA polymerase II chromatin transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery gastrulation with mouth forming second hair follicle development DNA binding chromatin binding transcription coactivator activity protein binding nucleus nucleus nucleoplasm transcription regulator complex transcription regulator complex transcription regulator complex transcription regulator complex transcription by RNA polymerase II cell adhesion multicellular organism development nervous system development anterior/posterior axis specification epithelial structure maintenance Wnt signaling pathway enzyme binding enzyme binding cerebellum development cerebellar Purkinje cell differentiation cellular component assembly neuron differentiation LIM domain binding LIM domain binding LIM domain binding LIM domain binding regulation of cell migration cell leading edge positive regulation of transcription elongation by RNA polymerase II protein-containing complex protein-containing complex somatic stem cell population maintenance identical protein binding protein homodimerization activity regulation of kinase activity protein self-association negative regulation of erythrocyte differentiation positive regulation of cell adhesion negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of hemoglobin biosynthetic process regulation of focal adhesion assembly primitive erythrocyte differentiation head development RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II transcription regulator complex DNA-binding transcription factor binding DNA-binding transcription factor binding beta-catenin-TCF complex |
|
| 1434499_a_at |
Ldhb |
lactate dehydrogenase B |
6 |
-142490248 |
AV219418 |
16832 |
77 |
catalytic activity lactate dehydrogenase activity L-lactate dehydrogenase activity L-lactate dehydrogenase activity L-lactate dehydrogenase activity cytoplasm mitochondrion mitochondrion mitochondrial inner membrane cytosol cytosol lactate metabolic process lactate metabolic process pyruvate metabolic process pyruvate metabolic process membrane oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor lactate biosynthetic process from pyruvate NAD metabolic process carboxylic acid metabolic process kinase binding identical protein binding myelin sheath membrane raft NAD binding oxidoreductase complex |
00010 00270 00620 00640 01100 |
| 1454734_at |
Lef1 |
lymphoid enhancer binding factor 1 |
3 |
131110296, 131112790, 131156293, 131110322, 131112790 |
AV156352 |
16842 |
676 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding transcription corepressor binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific branching involved in blood vessel morphogenesis somitogenesis somitogenesis epithelial to mesenchymal transition vasculature development sprouting angiogenesis nucleic acid binding DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex transcription regulator complex transcription regulator complex cytoplasm cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II beta-catenin binding transcription factor binding DNA binding, bending DNA binding, bending positive regulation of gene expression positive regulation of epithelial to mesenchymal transition Wnt signaling pathway dentate gyrus development hippocampus development forebrain radial glial cell differentiation forebrain neuroblast division formation of radial glial scaffolds regulation of cell-cell adhesion regulation of Wnt signaling pathway positive regulation of Wnt signaling pathway neutrophil differentiation embryonic limb morphogenesis nuclear estrogen receptor binding positive regulation of cell migration BMP signaling pathway positive regulation of granulocyte differentiation mammary gland development negative regulation of interleukin-13 production negative regulation of interleukin-4 production negative regulation of interleukin-5 production protein-DNA complex T cell receptor V(D)J recombination B cell proliferation histone binding odontogenesis of dentin-containing tooth odontogenesis of dentin-containing tooth histone deacetylase binding negative regulation of apoptotic process negative regulation of DNA binding sequence-specific DNA binding sequence-specific DNA binding tongue development positive regulation by host of viral transcription T-helper 1 cell differentiation gamma-catenin binding positive regulation of gamma-delta T cell differentiation positive regulation of cell differentiation negative regulation of striated muscle tissue development negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II alpha-beta T cell differentiation paraxial mesoderm formation cell development regulation of neurogenesis sensory perception of taste anatomical structure regression canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway face morphogenesis cell chemotaxis apoptotic process involved in morphogenesis chorio-allantoic fusion trachea gland development secondary palate development armadillo repeat domain binding C2H2 zinc finger domain binding protein localization to chromatin cellular response to cytokine stimulus cellular response to interleukin-4 positive regulation of cell proliferation in bone marrow negative regulation of apoptotic process in bone marrow cell odontoblast differentiation positive regulation of cell cycle process RNA polymerase II transcription regulator complex transcription regulator inhibitor activity positive regulation of odontoblast differentiation apoptotic process involved in blood vessel morphogenesis positive regulation of chondrocyte proliferation epithelial cell apoptotic process sequence-specific double-stranded DNA binding beta-catenin-TCF complex beta-catenin-TCF complex beta-catenin-TCF complex |
04310 04520 04916 05200 05210 05213 05215 05216 05217 05221 05412 |
| 1426808_at |
Lgals3 |
lectin, galactose binding, soluble 3 |
14 |
47373859 |
X16834 |
16854 |
428 |
skeletal system development cornified envelope immunological synapse immunological synapse immunological synapse immune system process monocyte chemotaxis monocyte chemotaxis protein binding extracellular region extracellular region extracellular space extracellular space extracellular space nucleus nucleus nucleus nucleoplasm spliceosomal complex cytoplasm cytoplasm cytoplasm mitochondrial inner membrane cytosol mRNA processing positive regulation of cell population proliferation RNA splicing external side of plasma membrane cell surface cell surface positive regulation of serotonin secretion IgE binding IgE binding protein phosphatase binding cell differentiation extracellular matrix organization carbohydrate binding neutrophil chemotaxis neutrophil chemotaxis extracellular matrix positive regulation of protein-containing complex assembly killing of cells of another organism Fc-gamma receptor I complex binding chemoattractant activity regulation of T cell proliferation negative regulation of apoptotic process laminin binding laminin binding innate immune response positive regulation of angiogenesis negative regulation of endocytosis negative regulation of endocytosis negative regulation of endocytosis monosaccharide binding disaccharide binding disaccharide binding eosinophil chemotaxis eosinophil chemotaxis macrophage chemotaxis macrophage chemotaxis advanced glycation end-product receptor activity negative regulation of T cell receptor signaling pathway positive chemotaxis positive chemotaxis antimicrobial humoral immune response mediated by antimicrobial peptide collagen-containing extracellular matrix regulation of T cell apoptotic process oligosaccharide binding mononuclear cell migration positive regulation of mononuclear cell migration positive regulation of calcium ion import positive regulation of calcium ion import glial cell projection molecular condensate scaffold activity regulation of extrinsic apoptotic signaling pathway via death domain receptors positive regulation of protein localization to plasma membrane negative regulation of cell proliferation in bone marrow negative regulation of immunological synapse formation negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell negative regulation of extrinsic apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway |
|
| 1421217_a_at |
Lgals9 |
lectin, galactose binding, soluble 9 |
11 |
-78962978 |
NM_010708 |
16859 |
121 |
positive regulation of cytokine production immune system process signaling receptor binding protein binding extracellular region extracellular region extracellular space nucleus nucleus nucleus cytoplasm cytoplasm cytosol cytosol chemotaxis heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules transforming growth factor beta receptor signaling pathway female pregnancy positive regulation of gene expression negative regulation of gene expression galactoside binding galactoside binding galactoside binding enzyme binding enzyme binding carbohydrate binding carbohydrate binding carbohydrate binding carbohydrate binding response to lipopolysaccharide negative regulation of type II interferon production negative regulation of type II interferon production negative regulation of type II interferon production positive regulation of chemokine production positive regulation of interleukin-1 production positive regulation of interleukin-10 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production negative regulation of natural killer cell activation regulation of natural killer cell differentiation positive regulation of macrophage activation receptor clustering negative regulation of natural killer cell degranulation protein serine/threonine kinase activator activity positive regulation of innate immune response maintenance of protein location positive regulation of regulatory T cell differentiation disaccharide binding negative regulation of inflammatory response positive regulation of oxidoreductase activity positive regulation of SMAD protein signal transduction collagen-containing extracellular matrix cellular response to virus positive regulation of defense response to bacterium positive regulation of T cell migration negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of CD4-positive, alpha-beta T cell proliferation |
|
| 1454984_at |
Lifr |
LIF receptor alpha |
15 |
7129571, 7140541, 7129571 |
AV246615 |
16880 |
116 |
cytokine receptor activity cytokine receptor activity ciliary neurotrophic factor receptor activity leukemia inhibitory factor receptor activity oncostatin-M receptor activity oncostatin-M receptor activity ciliary neurotrophic factor receptor binding ciliary neurotrophic factor receptor binding protein binding extracellular region plasma membrane positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation external side of plasma membrane negative regulation of muscle cell apoptotic process membrane cytokine-mediated signaling pathway cytokine-mediated signaling pathway growth factor binding cytokine binding cytokine binding animal organ regeneration response to cytokine oncostatin-M-mediated signaling pathway receptor complex receptor complex neuron projection morphogenesis leukemia inhibitory factor signaling pathway ciliary neurotrophic factor-mediated signaling pathway |
04060 04630 |
| 1421262_at |
Lipg |
lipase, endothelial |
18 |
-74939321 |
BC020991 |
16891 |
61 |
lipoprotein lipase activity lipoprotein lipase activity phospholipase activity phospholipase activity triglyceride lipase activity extracellular region extracellular space extracellular space early endosome Golgi apparatus lipid metabolic process fatty acid biosynthetic process heparin binding phospholipase A1 activity phospholipase A1 activity cell surface positive regulation of high-density lipoprotein particle clearance lipid catabolic process lipase activity hydrolase activity triglyceride catabolic process positive regulation of cholesterol transport high-density lipoprotein particle remodeling high-density lipoprotein particle remodeling cholesterol homeostasis cholesterol homeostasis reverse cholesterol transport regulation of lipoprotein metabolic process carboxylic ester hydrolase activity phosphatidylserine 1-acylhydrolase activity 1-acyl-2-lysophosphatidylserine acylhydrolase activity phospholipid homeostasis |
00561 01100 |
| 1423520_at |
Lmnb1 |
lamin B1 |
18 |
56707812 |
AA270173 |
16906 |
164 |
double-stranded DNA binding structural constituent of cytoskeleton structural constituent of cytoskeleton nucleus nucleus nuclear envelope nuclear envelope nuclear envelope nuclear envelope nuclear inner membrane lamin filament nuclear lamina nuclear lamina nuclear lamina nucleoplasm nucleoplasm intermediate filament nuclear envelope organization nuclear envelope organization nuclear migration JUN kinase binding positive regulation of G2/M transition of mitotic cell cycle nuclear matrix nuclear matrix heterochromatin formation nuclear membrane nuclear periphery phospholipase binding positive regulation of JNK cascade nuclear pore localization protein localization to nuclear envelope cellular response to L-glutamate sequence-specific double-stranded DNA binding |
|
| 1460194_at |
Phyh |
phytanoyl-CoA hydroxylase |
2 |
4918995 |
NM_010726 |
16922 |
29 |
fatty acid alpha-oxidation fatty acid alpha-oxidation fatty acid alpha-oxidation catalytic activity protein binding mitochondrion peroxisome peroxisome peroxisomal matrix 2-oxoglutarate metabolic process isoprenoid metabolic process ferrous iron binding oxidoreductase activity 2-oxobutyrate catabolic process carboxylic acid binding L-ascorbic acid binding metal ion binding phytanoyl-CoA dioxygenase activity phytanoyl-CoA dioxygenase activity dioxygenase activity methyl-branched fatty acid metabolic process 9+0 non-motile cilium |
04146 |
| 1448213_at |
Anxa1 |
annexin A1 |
19 |
-20373433 |
NM_010730 |
16952 |
251 |
cornified envelope cornified envelope neutrophil homeostasis neutrophil homeostasis phosphatidylserine binding adaptive immune response immune system process monocyte chemotaxis regulation of leukocyte migration single-stranded DNA binding single-stranded RNA binding phospholipase inhibitor activity calcium ion binding protein binding phospholipid binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding extracellular region extracellular space nucleus nucleoplasm cytoplasm cytoplasm cytoplasm endosome cytosol cytosol actin filament plasma membrane plasma membrane plasma membrane cilium phagocytosis phagocytosis inflammatory response signal transduction signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger lipid binding regulation of cell shape cell surface myoblast migration involved in skeletal muscle regeneration membrane apical plasma membrane lateral plasma membrane peptide cross-linking phospholipase A2 inhibitor activity actin cytoskeleton organization insulin secretion keratinocyte differentiation positive regulation of vesicle fusion positive regulation of prostaglandin biosynthetic process cytoplasmic vesicle motile cilium mitochondrial membrane DNA duplex unwinding regulation of interleukin-1 production negative regulation of interleukin-8 production positive regulation of interleukin-2 production protein-containing complex positive regulation of neutrophil apoptotic process cellular response to vascular endothelial growth factor stimulus double-stranded DNA helicase activity positive regulation of T cell proliferation neutrophil activation regulation of cell population proliferation sarcolemma mast cell granule identical protein binding cell projection positive regulation of apoptotic process innate immune response positive regulation of T-helper 1 cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of exocytosis alpha-beta T cell differentiation metal ion binding regulation of hormone secretion calcium-dependent protein binding arachidonic acid secretion negative regulation of protein secretion regulation of inflammatory response localization collagen-containing extracellular matrix extracellular exosome cellular response to hydrogen peroxide prolactin secretion cellular response to glucocorticoid stimulus cellular response to glucocorticoid stimulus cellular response to glucocorticoid stimulus granulocyte chemotaxis positive regulation of cell migration involved in sprouting angiogenesis positive regulation of wound healing synaptic membrane neutrophil clearance positive regulation of G1/S transition of mitotic cell cycle DNA/DNA annealing activity |
|
| 1448655_at |
Lrp1 |
low density lipoprotein receptor-related protein 1 |
10 |
-127538157 |
NM_008512 |
16971 |
382 |
protease binding astrocyte activation involved in immune response cardiac septum development signaling receptor binding calcium ion binding protein binding nucleus cytoplasm endosome early endosome Golgi apparatus cytoskeleton plasma membrane plasma membrane clathrin-coated pit endocytosis receptor-mediated endocytosis receptor-mediated endocytosis receptor-mediated endocytosis receptor-mediated endocytosis receptor-mediated endocytosis phagocytosis phagocytosis lysosomal transport enzyme-linked receptor protein signaling pathway positive regulation of cytosolic calcium ion concentration protein kinase C-activating G protein-coupled receptor signaling pathway multicellular organism development cholesterol metabolic process external side of plasma membrane negative regulation of gene expression negative regulation of cell-substrate adhesion positive regulation of cholesterol efflux positive regulation of neuron projection development negative regulation of neuron projection development negative regulation of smooth muscle cell migration coreceptor activity membrane basolateral plasma membrane alpha-2 macroglobulin receptor activity clathrin-coated vesicle negative regulation of Wnt signaling pathway dendrite negative regulation of transforming growth factor beta receptor signaling pathway clathrin heavy chain binding positive regulation of protein binding positive regulation of lipid transport regulation of cholesterol transport regulation of phospholipase A2 activity insulin-responsive compartment regulation of actin cytoskeleton organization apolipoprotein binding apolipoprotein binding positive regulation of insulin secretion involved in cellular response to glucose stimulus aorta morphogenesis cargo receptor activity cargo receptor activity cargo receptor activity neuronal cell body negative regulation of apoptotic process receptor complex apoptotic cell clearance negative regulation of neuron apoptotic process cellular lipid catabolic process axonal growth cone protein-containing complex binding apical part of cell positive regulation of axon extension positive regulation of endocytosis metal ion binding perinuclear region of cytoplasm positive regulation of axon extension involved in regeneration positive regulation of collateral sprouting of injured axon positive regulation of phagocytosis positive regulation of protein transport negative regulation of cytosolic calcium ion concentration negative regulation of focal adhesion assembly negative regulation of SMAD protein signal transduction coronary vasculature development chemoattraction of axon positive regulation of ERK1 and ERK2 cascade amyloid-beta clearance amyloid-beta clearance by transcytosis amyloid-beta clearance by transcytosis amyloid-beta clearance by transcytosis amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process transport across blood-brain barrier positive regulation of Schwann cell migration positive regulation of amyloid-beta clearance positive regulation of protein localization to plasma membrane positive regulation of cholesterol import positive regulation of transcytosis cellular response to amyloid-beta positive regulation of vascular associated smooth muscle cell migration regulation of pulmonary blood vessel remodeling positive regulation of lysosomal protein catabolic process positive regulation of chemokine (C-X-C motif) ligand 2 production negative regulation of platelet-derived growth factor receptor-beta signaling pathway |
05010 05144 |
| 1419135_at |
Ltb |
lymphotoxin B |
17 |
35194506 |
NM_008518 |
16994 |
169 |
cytokine activity tumor necrosis factor receptor binding extracellular space plasma membrane immune response gene expression membrane positive regulation of interleukin-12 production positive regulation of canonical NF-kappaB signal transduction skin development lymph node development positive regulation of extrinsic apoptotic signaling pathway |
04060 05323 |
| 1420407_at |
Ltb4r1 |
leukotriene B4 receptor 1 |
14 |
55765961 |
NM_008519 |
16995 |
143 |
leukotriene B4 receptor activity leukotriene B4 receptor activity G protein-coupled receptor activity leukotriene receptor activity plasma membrane signal transduction G protein-coupled receptor signaling pathway neuropeptide signaling pathway G protein-coupled peptide receptor activity membrane |
04080 |
| 1416435_at |
Ltbr |
lymphotoxin B receptor |
6 |
-125306570 |
NM_010736 |
17000 |
231 |
protein binding Golgi apparatus plasma membrane apoptotic process immune response membrane ubiquitin protein ligase binding ubiquitin protein ligase binding identical protein binding myeloid dendritic cell differentiation positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of JNK cascade hematopoietic or lymphoid organ development lymph node development positive regulation of extrinsic apoptotic signaling pathway |
04060 04672 |
| 1450009_at |
Ltf |
lactotransferrin |
9 |
111019291 |
NM_008522 |
17002 |
112 |
ossification lipopolysaccharide binding regulation of cytokine production innate immune response in mucosa immune system process serine-type endopeptidase activity cysteine-type endopeptidase inhibitor activity iron ion binding extracellular region extracellular space extracellular space cytoplasm cytoplasm early endosome plasma membrane proteolysis monoatomic ion transport iron ion transport iron ion transport heparin binding peptidase activity serine-type peptidase activity cell surface hydrolase activity antibacterial humoral response antibacterial humoral response antifungal humoral response secretory granule killing of cells of another organism negative regulation of lipopolysaccharide-mediated signaling pathway regulation of tumor necrosis factor production negative regulation of ATP-dependent activity protein-containing complex positive regulation of osteoblast proliferation positive regulation of toll-like receptor 4 signaling pathway specific granule positive regulation of canonical NF-kappaB signal transduction protein serine/threonine kinase activator activity negative regulation by host of viral process negative regulation of viral genome replication innate immune response positive regulation of osteoblast differentiation negative regulation of membrane potential metal ion binding negative regulation of viral process defense response to Gram-negative bacterium defense response to Gram-positive bacterium positive regulation of NF-kappaB transcription factor activity cytolysis by host of symbiont cells recycling endosome bone morphogenesis antimicrobial humoral immune response mediated by antimicrobial peptide positive regulation of protein serine/threonine kinase activity membrane destabilizing activity negative regulation of single-species biofilm formation in or on host organism positive regulation of chondrocyte proliferation negative regulation of cysteine-type endopeptidase activity |
|
| 1451780_at |
Blnk |
B cell linker |
19 |
-40928926 |
AF068182 |
17060 |
110 |
protein binding cytoplasm cytoplasm cytosol plasma membrane transmembrane receptor protein tyrosine kinase signaling pathway lipid binding positive regulation of gene expression membrane enzyme binding protein kinase binding intracellular signal transduction intracellular signal transduction signaling adaptor activity B cell activation SH2 domain binding intracellular membrane-bounded organelle phospholipase binding B cell receptor signaling pathway protein tyrosine kinase binding |
04380 04662 05340 |
| 1416359_at |
Snx18 |
sorting nexin 18 |
13 |
-113592178 |
AV344473 |
170625 |
23 |
mitotic cell cycle mitotic cytokinesis protein binding phosphatidylinositol-4,5-bisphosphate binding endosome plasma membrane plasma membrane endocytosis endocytosis cell cycle lipid binding cytoplasmic side of plasma membrane protein transport membrane endosomal transport endosomal transport clathrin-coated vesicle growth cone cytoplasmic vesicle cytoplasmic vesicle phosphatidylinositol binding phosphatidylinositol binding cleavage furrow formation cleavage furrow formation neuronal cell body positive regulation of GTPase activity cell division recycling endosome membrane extracellular exosome plasma membrane tubulation positive regulation of autophagosome assembly |
|
| 1416930_at |
Ly6d |
lymphocyte antigen 6 family member D |
15 |
-74762055 |
NM_010742 |
17068 |
32 |
plasma membrane cell surface cell surface membrane lymphocyte differentiation lymphocyte differentiation response to stilbenoid side of membrane |
|
| 1422041_at |
Pilrb1 |
paired immunoglobin-like type 2 receptor beta 1 |
5 |
-137852146 |
NM_133209 |
170741 |
12 |
myeloid dendritic cell activation protein binding plasma membrane membrane MHC class I protein binding MHC class I protein binding negative regulation of osteoclast differentiation |
|
| 1426218_at |
Glcci1 |
glucocorticoid induced transcript 1 |
6 |
8520057, 8509599 |
AA152997 |
170772 |
34 |
cytoplasm cytoplasm |
|
| 1454775_at |
Hdac10 |
histone deacetylase 10 |
15 |
-89123302 |
AW548891 |
170787 |
28 |
histone deacetylase complex negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II histone deacetylase activity nucleus nucleoplasm cytoplasm cytosol DNA repair DNA recombination chromatin organization chromatin remodeling regulation of DNA-templated transcription autophagy DNA damage response macroautophagy hydrolase activity deacetylase activity deacetylase activity enzyme binding positive regulation of mismatch repair peptidyl-lysine deacetylation homologous recombination histone deacetylase binding intracellular membrane-bounded organelle negative regulation of DNA-templated transcription metal ion binding acetylputrescine deacetylase activity acetylspermidine deacetylase activity polyamine deacetylation spermidine deacetylation |
|
| 1438398_at |
Rbm39 |
RNA binding motif protein 39 |
2 |
-156147240, -156147240 |
BB203348 |
170791 |
50 |
nucleic acid binding RNA binding protein binding nucleus nucleoplasm mRNA processing RNA splicing microtubule cytoskeleton nuclear speck protein-containing complex centriolar satellite regulation of mRNA splicing, via spliceosome RS domain binding U1 snRNP binding |
|
| 1449874_at |
Ly96 |
lymphocyte antigen 96 |
1 |
16688455 |
NM_016923 |
17087 |
127 |
lipopolysaccharide binding lipopolysaccharide immune receptor activity lipopolysaccharide immune receptor activity toll-like receptor signaling pathway immune system process protein binding extracellular region plasma membrane inflammatory response lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway positive regulation of lipopolysaccharide-mediated signaling pathway positive regulation of lipopolysaccharide-mediated signaling pathway positive regulation of lipopolysaccharide-mediated signaling pathway positive regulation of lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide detection of lipopolysaccharide detection of lipopolysaccharide positive regulation of tumor necrosis factor production toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway Toll-like receptor 4 binding receptor complex innate immune response lipopolysaccharide receptor complex lipopolysaccharide receptor complex lipopolysaccharide receptor complex cellular response to lipopolysaccharide cellular response to lipopolysaccharide |
04620 05145 |
| 1439200_x_at |
Erdr1x |
erythroid differentiation regulator 1 x |
X, Y |
90785441 |
BE686792 |
170942 |
31 |
molecular_function cellular_component negative regulation of cell population proliferation negative regulation of cell migration somatic stem cell population maintenance |
|
| 1437540_at |
Mcoln3 |
mucolipin 3 |
3 |
146121790 |
AV313762 |
171166 |
55 |
monoatomic cation channel activity cytoplasm lysosomal membrane endosome plasma membrane plasma membrane monoatomic ion transport sensory perception of sound locomotory behavior lipid binding membrane cytoplasmic vesicle monoatomic ion transmembrane transport inner ear auditory receptor cell differentiation cell projection NAADP-sensitive calcium-release channel activity |
|
| 1434678_at |
Mbnl3 |
muscleblind like splicing factor 3 |
X |
-51113493 |
AV306759 |
171170 |
31 |
RNA binding nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytosol mRNA processing multicellular organism development RNA splicing regulation of RNA splicing regulation of RNA splicing negative regulation of myoblast differentiation metal ion binding |
|
| 1455104_at |
Mxd1 |
MAX dimerization protein 1 |
6 |
-86647044 |
AV228517 |
17119 |
49 |
negative regulation of transcription by RNA polymerase II chromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding protein binding nucleus nucleoplasm mitochondrion cytosol regulation of transcription by RNA polymerase II protein dimerization activity Mad-Max complex |
|
| 1440162_x_at |
Edaradd |
EDAR associated via death domain |
13 |
-12471208 |
BB446560 |
171211 |
53 |
hair follicle development death receptor binding protein binding cytoplasm signal transduction canonical NF-kappaB signal transduction multicellular organism development cell differentiation odontogenesis of dentin-containing tooth trachea gland development positive regulation of non-canonical NF-kappaB signal transduction |
|
| 1422486_a_at |
Smad4 |
SMAD family member 4 |
18 |
-73634790 |
AK004804 |
17128 |
546 |
negative regulation of transcription by RNA polymerase II chromatin transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific transcription corepressor binding transcription coactivator binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific ovarian follicle development ovarian follicle development osteoblast differentiation branching involved in ureteric bud morphogenesis response to hypoxia in utero embryonic development gastrulation with mouth forming second kidney development epithelial to mesenchymal transition outflow tract septum morphogenesis atrioventricular valve formation epithelial to mesenchymal transition involved in endocardial cushion formation left ventricular cardiac muscle tissue morphogenesis positive regulation of cell proliferation involved in heart valve morphogenesis cardiac septum development brainstem development DNA binding DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding collagen binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex transcription regulator complex cytoplasm cytoplasm centrosome cytosol DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II intracellular iron ion homeostasis transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway spermatogenesis single fertilization gastrulation axon guidance endoderm development mesoderm development cell population proliferation cell population proliferation negative regulation of cell population proliferation male gonad development female gonad development anatomical structure morphogenesis anatomical structure morphogenesis anterior/posterior pattern specification negative regulation of cardiac muscle hypertrophy positive regulation of gene expression epithelial cell migration positive regulation of cardiac muscle cell apoptotic process positive regulation of epithelial to mesenchymal transition neural crest cell differentiation cardiac muscle hypertrophy in response to stress regulation of transforming growth factor beta receptor signaling pathway cell differentiation cell differentiation negative regulation of cell growth BMP signaling pathway BMP signaling pathway BMP signaling pathway positive regulation of transforming growth factor beta receptor signaling pathway filamin binding activin responsive factor complex somite rostral/caudal axis specification regulation of transforming growth factor beta2 production activin receptor signaling pathway protein-containing complex positive regulation of luteinizing hormone secretion positive regulation of luteinizing hormone secretion intracellular signal transduction atrioventricular canal development endothelial cell activation regulation of cell population proliferation regulation of cell population proliferation negative regulation of protein catabolic process embryonic digit morphogenesis identical protein binding identical protein binding protein homodimerization activity sulfate binding sequence-specific DNA binding protein-containing complex binding negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II SMAD binding metal ion binding positive regulation of follicle-stimulating hormone secretion positive regulation of follicle-stimulating hormone secretion mesendoderm development developmental growth neuron fate commitment neuron fate specification tissue morphogenesis sebaceous gland development formation of anatomical boundary regulation of binding regulation of hair follicle development uterus development positive regulation of SMAD protein signal transduction SMAD protein signal transduction SMAD protein signal transduction SMAD protein signal transduction ventricular septum morphogenesis endocardial cell differentiation female gonad morphogenesis RNA polymerase II-specific DNA-binding transcription factor binding secondary palate development interleukin-6-mediated signaling pathway ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade I-SMAD binding I-SMAD binding R-SMAD binding SMAD protein complex heteromeric SMAD protein complex heteromeric SMAD protein complex heteromeric SMAD protein complex cellular response to glucose stimulus response to transforming growth factor beta cellular response to transforming growth factor beta stimulus metanephric mesenchyme morphogenesis nephrogenic mesenchyme morphogenesis seminiferous tubule development negative regulation of canonical Wnt signaling pathway RNA polymerase II transcription regulator complex extrinsic apoptotic signaling pathway positive regulation of extracellular matrix assembly positive regulation of miRNA transcription negative regulation of cardiac myofibril assembly |
04110 04310 04350 04520 05200 05210 05212 05220 |
| 1443771_x_at |
Smad7 |
SMAD family member 7 |
18 |
75367364 |
BB241324 |
17131 |
269 |
negative regulation of transcription by RNA polymerase II fibrillar center ureteric bud development negative regulation of T cell cytokine production transcription corepressor activity protein binding collagen binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex cytoplasm centrosome cytosol cytosol plasma membrane adherens junction regulation of DNA-templated transcription regulation of transcription by RNA polymerase II transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway beta-catenin binding anatomical structure morphogenesis regulation of epithelial to mesenchymal transition negative regulation of peptidyl-threonine phosphorylation negative regulation of peptidyl-threonine phosphorylation negative regulation of transcription by competitive promoter binding regulation of transforming growth factor beta receptor signaling pathway positive regulation of cell-cell adhesion positive regulation of cell-cell adhesion cell differentiation negative regulation of ossification negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of BMP signaling pathway negative regulation of BMP signaling pathway negative regulation of protein ubiquitination protein-containing complex localization ubiquitin protein ligase binding negative regulation of activin receptor signaling pathway protein-containing complex protein-containing complex negative regulation of peptidyl-serine phosphorylation negative regulation of peptidyl-serine phosphorylation adherens junction assembly type I transforming growth factor beta receptor binding intracellular signal transduction metal ion binding artery morphogenesis protein stabilization negative regulation of ubiquitin-protein transferase activity ventricular cardiac muscle tissue morphogenesis regulation of cardiac muscle contraction regulation of ventricular cardiac muscle cell membrane depolarization negative regulation of SMAD protein signal transduction negative regulation of SMAD protein signal transduction SMAD protein signal transduction ventricular septum morphogenesis I-SMAD binding I-SMAD binding activin receptor binding heteromeric SMAD protein complex cellular response to transforming growth factor beta stimulus cellular response to transforming growth factor beta stimulus transcription regulator inhibitor activity transcription regulator inhibitor activity negative regulation of chondrocyte proliferation positive regulation of chondrocyte hypertrophy ubiquitin ligase-substrate adaptor activity cellular response to leukemia inhibitory factor negative regulation of T-helper 17 type immune response negative regulation of T-helper 17 cell differentiation |
04144 04350 |
| 1456060_at |
Maf |
MAF bZIP transcription factor |
8 |
-115703252 |
AV284857 |
17132 |
208 |
negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific cytokine production lens development in camera-type eye DNA binding double-stranded DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II positive regulation of gene expression megakaryocyte differentiation regulation of chondrocyte differentiation identical protein binding sequence-specific DNA binding protein-containing complex binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II cell development inner ear development lens fiber cell differentiation lens fiber cell differentiation RNA polymerase II transcription regulator complex sequence-specific double-stranded DNA binding |
|
| 1448647_at |
Man2a1 |
mannosidase 2, alpha 1 |
17 |
64601648 |
NM_008549 |
17158 |
42 |
Golgi membrane Golgi membrane Golgi membrane in utero embryonic development liver development catalytic activity alpha-mannosidase activity alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity extracellular space Golgi apparatus Golgi medial cisterna cis-Golgi network carbohydrate metabolic process mannose metabolic process N-glycan processing N-glycan processing N-glycan processing protein deglycosylation mitochondrion organization vacuole organization respiratory gaseous exchange by respiratory system metabolic process mannosidase activity membrane hydrolase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding identical protein binding protein homodimerization activity metal ion binding lung alveolus development positive regulation of neurogenesis retina morphogenesis in camera-type eye |
00510 01100 |
| 1456439_x_at |
Mical1 |
microtubule associated monooxygenase, calponin and LIM domain containing 1 |
10 |
41476313, 41478009 |
BB209438 |
171580 |
31 |
negative regulation of protein phosphorylation actin binding actin binding monooxygenase activity monooxygenase activity protein binding cytoplasm endosome cytosol cytoskeleton actin filament endosome membrane membrane NAD(P)H oxidase H2O2-forming activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen SH3 domain binding sulfur oxidation protein kinase binding actin filament depolymerization actin filament depolymerization midbody small GTPase binding negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process intercellular bridge metal ion binding FAD binding FAD binding regulation of regulated secretory pathway hippocampal mossy fiber expansion |
|
| 1449498_at |
Marco |
macrophage receptor with collagenous structure |
1 |
-120474537 |
NM_010766 |
17167 |
77 |
amyloid-beta binding G protein-coupled receptor binding immune system process collagen trimer extracellular space cytoplasm plasma membrane plasma membrane endocytosis receptor-mediated endocytosis phagocytosis, engulfment membrane extracellular matrix cargo receptor activity apoptotic cell clearance innate immune response amyloid-beta clearance |
04145 |
| 1434888_a_at |
Matr3 |
matrin 3 |
18 |
35562157 |
BM219545 |
17184 |
73 |
blastocyst formation activation of innate immune response immune system process heart valve development ventricular septum development nucleic acid binding RNA binding RNA binding nucleus nucleus zinc ion binding post-transcriptional regulation of gene expression nuclear matrix miRNA binding identical protein binding innate immune response metal ion binding |
|
| 1416881_at |
Mcl1 |
myeloid cell leukemia sequence 1 |
3 |
95658720 |
BC003839 |
17210 |
275 |
release of cytochrome c from mitochondria protein binding nucleus nucleus cytoplasm mitochondrion mitochondrion mitochondrial outer membrane cytosol apoptotic process DNA damage response multicellular organism development mitochondrial fusion intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of autophagy channel activity membrane membrane cell differentiation response to cytokine protein homodimerization activity regulation of apoptotic process positive regulation of apoptotic process positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process protein-containing complex binding protein heterodimerization activity protein heterodimerization activity protein dimerization activity BH domain binding BH3 domain binding BH3 domain binding Bcl-2 family protein complex extrinsic apoptotic signaling pathway in absence of ligand extrinsic apoptotic signaling pathway in absence of ligand extrinsic apoptotic signaling pathway in absence of ligand positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway negative regulation of anoikis negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
|
| 1449965_at |
Mcpt8 |
mast cell protease 8 |
14 |
-56082163 |
NM_008572 |
17231 |
57 |
serine-type endopeptidase activity extracellular region extracellular space cytoplasm proteolysis peptidase activity serine-type peptidase activity hydrolase activity intracellular membrane-bounded organelle |
|
| 1460542_s_at |
Mdm4 |
transformed mouse 3T3 cell double minute 4 |
1 |
-132986104, -132986104 |
BQ173933 |
17248 |
142 |
negative regulation of transcription by RNA polymerase II regulation of heart rate heart valve development atrioventricular valve morphogenesis endocardial cushion morphogenesis ventricular septum development atrial septum development ubiquitin-protein transferase activity protein binding nucleus nucleoplasm positive regulation of cell population proliferation protein ubiquitination transcription repressor complex enzyme binding negative regulation of protein catabolic process negative regulation of apoptotic process negative regulation of DNA-templated transcription metal ion binding regulation of cell cycle protein-containing complex assembly negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator |
04115 |
| 1424852_at |
Mef2c |
myocyte enhancer factor 2C |
13 |
83504033, 83573606, 83524742, 83523655 |
BB280300 |
17260 |
457 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II MAPK cascade MAPK cascade MAPK cascade transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development osteoblast differentiation osteoblast differentiation neuron migration B cell homeostasis heart looping endochondral ossification endochondral ossification blood vessel remodeling chondrocyte differentiation germinal center formation regulation of germinal center formation response to ischemia primary heart field specification secondary heart field specification outflow tract morphogenesis sinoatrial valve morphogenesis cardiac ventricle formation cardiac ventricle formation DNA binding DNA binding minor groove of adenine-thymine-rich DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytosol regulation of DNA-templated transcription regulation of DNA-templated transcription apoptotic process humoral immune response multicellular organism development nervous system development axon guidance heart development heart development skeletal muscle tissue development muscle cell fate determination learning or memory gene expression positive regulation of cardiac muscle hypertrophy positive regulation of gene expression positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of alkaline phosphatase activity neural crest cell differentiation cardiac muscle hypertrophy in response to stress nuclear speck sarcomere cell differentiation cell differentiation neuron differentiation platelet formation monocyte differentiation negative regulation of ossification melanocyte differentiation positive regulation of bone mineralization positive regulation of B cell proliferation protein-containing complex embryonic heart tube development embryonic heart tube development skeletal muscle cell differentiation skeletal muscle cell differentiation cellular response to trichostatin A B cell proliferation histone deacetylase binding histone deacetylase binding intracellular membrane-bounded organelle positive regulation of MAPK cascade regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of blood vessel endothelial cell migration sequence-specific DNA binding cell fate commitment regulation of megakaryocyte differentiation positive regulation of myoblast differentiation positive regulation of neuron differentiation positive regulation of osteoblast differentiation positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of neurotransmitter secretion protein heterodimerization activity protein dimerization activity regulation of synaptic plasticity positive regulation of skeletal muscle tissue development neuron development cell morphogenesis involved in neuron differentiation embryonic viscerocranium morphogenesis embryonic skeletal system morphogenesis negative regulation of epithelial cell proliferation B cell receptor signaling pathway smooth muscle cell differentiation regulation of synapse assembly regulation of synaptic transmission, glutamatergic cardiac muscle cell differentiation cardiac muscle cell differentiation ventricular cardiac muscle cell differentiation roof of mouth development regulation of synaptic activity positive regulation of cardiac muscle cell proliferation excitatory postsynaptic potential transdifferentiation regulation of sarcomere organization cartilage morphogenesis regulation of dendritic spine development renal tubule morphogenesis RNA polymerase II-specific DNA-binding transcription factor binding cellular response to lipopolysaccharide cellular response to calcium ion cellular response to retinoic acid cellular response to growth factor stimulus cellular response to parathyroid hormone stimulus cellular response to xenobiotic stimulus cellular response to fluid shear stress cellular response to transforming growth factor beta stimulus HMG box domain binding cell proliferation in bone marrow positive regulation of cell proliferation in bone marrow glomerulus morphogenesis nephron tubule epithelial cell differentiation sympathetic neuron axon guidance DNA-binding transcription factor binding semaphorin-plexin signaling pathway involved in axon guidance negative regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration negative regulation of vascular endothelial cell proliferation sequence-specific double-stranded DNA binding positive regulation of macrophage apoptotic process regulation of NMDA receptor activity regulation of AMPA receptor activity positive regulation of cardiac muscle cell differentiation positive regulation of cardiac muscle cell differentiation positive regulation of behavioral fear response epithelial cell proliferation involved in renal tubule morphogenesis positive regulation of skeletal muscle cell differentiation |
04010 |
| 1434487_at |
Mef2d |
myocyte enhancer factor 2D |
3 |
88142371 |
AV334508 |
17261 |
130 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific osteoblast differentiation endochondral ossification chondrocyte differentiation DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm regulation of DNA-templated transcription apoptotic process multicellular organism development nervous system development enzyme binding cell differentiation cell differentiation skeletal muscle cell differentiation protein homodimerization activity histone deacetylase binding histone deacetylase binding intracellular membrane-bounded organelle positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein heterodimerization activity protein dimerization activity RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription factor binding positive regulation of vascular associated smooth muscle cell proliferation sequence-specific double-stranded DNA binding |
|
| 1422869_at |
Mertk |
MER proto-oncogene tyrosine kinase |
2 |
128698914 |
NM_008587 |
17289 |
238 |
nucleotide binding photoreceptor outer segment natural killer cell differentiation negative regulation of cytokine production protein kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity ATP binding extracellular space cytoplasm plasma membrane protein phosphorylation phagocytosis phagocytosis transmembrane receptor protein tyrosine kinase signaling pathway multicellular organism development spermatogenesis nervous system development membrane kinase activity phosphorylation cell migration transferase activity platelet activation secretion by cell positive regulation of kinase activity substrate adhesion-dependent cell spreading receptor complex apoptotic cell clearance apoptotic cell clearance apoptotic cell clearance lymphocyte activation positive regulation of phagocytosis negative regulation of lymphocyte activation establishment of localization in cell positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction retina development in camera-type eye vagina development neutrophil clearance negative regulation of leukocyte apoptotic process |
|
| 1434447_at |
Met |
met proto-oncogene |
6 |
17463956 |
BG060788 |
17295 |
431 |
negative regulation of transcription by RNA polymerase II nucleotide binding neuron migration endothelial cell morphogenesis liver development liver development placenta development protein kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity hepatocyte growth factor receptor activity hepatocyte growth factor receptor activity hepatocyte growth factor receptor activity protein binding ATP binding extracellular space protein phosphorylation phagocytosis transmembrane receptor protein tyrosine kinase signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway chemical synaptic transmission multicellular organism development nervous system development brain development muscle organ development muscle organ development skeletal muscle tissue development beta-catenin binding basal plasma membrane basal plasma membrane positive regulation of gene expression negative regulation of gene expression positive regulation of peptidyl-threonine phosphorylation negative regulation of peptidyl-threonine phosphorylation positive regulation of glucose transmembrane transport positive regulation of neuron projection development muscle cell migration myotube differentiation membrane kinase activity phosphorylation cell migration transferase activity semaphorin receptor activity protein phosphatase binding neuron differentiation flagellated sperm motility dendrite adult behavior pancreas development positive regulation of microtubule polymerization regulation of interleukin-6 production positive regulation of peptidyl-serine phosphorylation positive regulation of kinase activity negative regulation of Rho protein signal transduction sperm flagellum glucose homeostasis identical protein binding neuronal cell body receptor complex phospholipase binding positive regulation of MAPK cascade phosphatidylinositol 3-kinase binding protein-containing complex binding postsynaptic membrane positive regulation of DNA replication positive regulation of mitotic nuclear division positive regulation of transcription by RNA polymerase II protein autophosphorylation hepatocyte growth factor receptor signaling pathway branching morphogenesis of an epithelial tube positive regulation of dendrite morphogenesis modulation of chemical synaptic transmission positive chemotaxis positive chemotaxis myoblast proliferation negative regulation of stress fiber assembly establishment of localization in cell cardiac muscle cell development cardiac muscle contraction excitatory synapse excitatory postsynaptic potential regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling establishment of skin barrier negative regulation of thrombin-activated receptor signaling pathway semaphorin-plexin signaling pathway semaphorin-plexin signaling pathway negative regulation of transforming growth factor beta production reactive oxygen species metabolic process molecular function activator activity regulation of cellular response to oxidative stress positive regulation of p38MAPK cascade negative regulation of hydrogen peroxide-mediated programmed cell death glucose transmembrane transport negative regulation of guanyl-nucleotide exchange factor activity positive regulation of endothelial cell chemotaxis |
04060 04144 04360 04510 04520 05100 05144 05200 05211 05218 |
| 1418652_at |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
5 |
-92321330 |
NM_008599 |
17329 |
136 |
cytokine activity extracellular region extracellular space extracellular space chemotaxis defense response inflammatory response inflammatory response immune response adenylate cyclase-activating G protein-coupled receptor signaling pathway chemokine activity chemokine activity response to bacterium external side of plasma membrane neutrophil chemotaxis killing of cells of another organism regulation of cell population proliferation CXCR chemokine receptor binding positive regulation of myoblast differentiation CXCR3 chemokine receptor binding positive regulation of release of sequestered calcium ion into cytosol defense response to virus antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide chemokine-mediated signaling pathway cellular response to lipopolysaccharide positive regulation of myoblast fusion |
04060 04062 04620 |
| 1455214_at |
Mitf |
melanogenesis associated transcription factor |
6 |
97991782, 97929816, 97807057 |
BB763517 |
17342 |
528 |
negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleus cytoplasm lysosome lysosomal membrane DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II multicellular organism development regulation of gene expression positive regulation of gene expression membrane Wnt signaling pathway cell differentiation osteoclast differentiation melanocyte differentiation melanocyte differentiation melanocyte differentiation negative regulation of cell migration protein-containing complex regulation of cell population proliferation camera-type eye development negative regulation of apoptotic process pigmentation pigmentation sequence-specific DNA binding cell fate commitment regulation of osteoclast differentiation regulation of osteoclast differentiation positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II bone remodeling protein dimerization activity protein-containing complex assembly E-box binding E-box binding melanocyte apoptotic process positive regulation of DNA-templated transcription initiation regulation of RNA biosynthetic process |
04380 04916 05200 05218 |
| 1428725_at |
Pias2 |
protein inhibitor of activated STAT 2 |
18 |
77065679, 77065679, 77065207, 77065207 |
AK018146 |
17344 |
71 |
DNA binding transcription coregulator activity protein binding nucleus nucleus nucleoplasm nucleoplasm DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II zinc ion binding PML body transferase activity protein sumoylation protein sumoylation protein sumoylation SUMO transferase activity SUMO transferase activity SUMO transferase activity protein domain specific binding nuclear estrogen receptor binding androgen receptor signaling pathway ubiquitin protein ligase binding nuclear glucocorticoid receptor binding negative regulation of DNA-binding transcription factor activity positive regulation of DNA-templated transcription metal ion binding nuclear androgen receptor binding positive regulation of dendrite morphogenesis regulation of androgen receptor signaling pathway negative regulation of androgen receptor signaling pathway RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II-specific DNA-binding transcription factor binding SUMO ligase activity SUMO ligase activity |
04120 04630 05160 05200 05222 |
| 1437226_x_at |
Marcksl1 |
MARCKS-like 1 |
4 |
129513580 |
AV110584 |
17357 |
52 |
actin binding calmodulin binding cytoplasm cytoplasm cytoskeleton plasma membrane plasma membrane actin filament organization central nervous system development synaptic vesicle cell population proliferation positive regulation of cell population proliferation membrane presynaptic membrane actin filament binding regulation of presynaptic cytosolic calcium ion concentration presynaptic cytosol |
04666 05140 |
| 1448383_at |
Mmp14 |
matrix metallopeptidase 14 (membrane-inserted) |
14 |
54431597 |
NM_008608 |
17387 |
234 |
skeletal system development ossification endochondral ossification endopeptidase activity metalloendopeptidase activity metalloendopeptidase activity metalloendopeptidase activity integrin binding extracellular space extracellular space nucleus cytoplasm cytosol plasma membrane plasma membrane proteolysis peptidase activity metallopeptidase activity zinc ion binding response to hormone positive regulation of myotube differentiation positive regulation of protein processing membrane cell migration hydrolase activity extracellular matrix organization positive regulation of cell growth lung development positive regulation of cell migration collagen catabolic process collagen catabolic process extracellular matrix cytoplasmic vesicle zymogen activation zymogen activation zymogen activation chondrocyte proliferation macropinosome intermediate filament cytoskeleton positive regulation of B cell differentiation negative regulation of Notch signaling pathway metal ion binding embryonic cranial skeleton morphogenesis branching morphogenesis of an epithelial tube tissue remodeling negative regulation of focal adhesion assembly head development bone development metalloaminopeptidase activity craniofacial suture morphogenesis regulation of protein localization to plasma membrane positive regulation of macrophage migration |
04912 |
| 1449366_at |
Mmp8 |
matrix metallopeptidase 8 |
9 |
7558428 |
NM_008611 |
17394 |
102 |
endopeptidase activity endopeptidase activity metalloendopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity calcium ion binding extracellular region extracellular space extracellular space extracellular space proteolysis peptidase activity metallopeptidase activity zinc ion binding hydrolase activity protein catabolic process extracellular matrix organization collagen catabolic process collagen catabolic process extracellular matrix positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production tumor necrosis factor binding metal ion binding cellular response to lipopolysaccharide cellular response to lipopolysaccharide positive regulation of neuroinflammatory response positive regulation of neuroinflammatory response positive regulation of tumor necrosis factor-mediated signaling pathway positive regulation of microglial cell activation |
|
| 1448291_at |
Mmp9 |
matrix metallopeptidase 9 |
2 |
164948218 |
NM_013599 |
17395 |
1127 |
skeletal system development skeletal system development positive regulation of protein phosphorylation fibronectin binding positive regulation of leukocyte migration endopeptidase activity metalloendopeptidase activity metalloendopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity extracellular region extracellular space extracellular space proteolysis apoptotic process response to oxidative stress heart development embryo implantation peptidase activity peptidase activity metallopeptidase activity zinc ion binding response to xenobiotic stimulus cell migration hydrolase activity protein catabolic process extracellular matrix organization extracellular matrix organization extracellular matrix organization collagen catabolic process collagen catabolic process collagen catabolic process extracellular matrix positive regulation of synaptic plasticity protein-containing complex cellular response to reactive oxygen species identical protein binding positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of DNA binding protein-containing complex binding positive regulation of epidermal growth factor receptor signaling pathway positive regulation of angiogenesis metal ion binding negative regulation of fibroblast proliferation macrophage chemotaxis tissue remodeling positive regulation of keratinocyte migration collagen-containing extracellular matrix cellular response to cadmium ion cellular response to cell-matrix adhesion cellular response to UV-A positive regulation of release of cytochrome c from mitochondria positive regulation of receptor binding response to amyloid-beta positive regulation of vascular associated smooth muscle cell proliferation negative regulation of epithelial cell differentiation involved in kidney development negative regulation of intrinsic apoptotic signaling pathway negative regulation of cation channel activity negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
04670 05200 05219 |
| 1448788_at |
Cd200 |
CD200 molecule |
16 |
-45382134 |
AF004023 |
17470 |
116 |
protein binding plasma membrane negative regulation of cell population proliferation cell surface cell surface cell surface membrane axon axon negative regulation of NF-kappaB transcription factor activity negative regulation of interleukin-6 production positive regulation of CREB transcription factor activity heterotypic cell-cell adhesion heterotypic cell-cell adhesion neuron projection neuronal cell body neuronal cell body negative regulation of macrophage activation cell body regulation of immune response positive regulation of transforming growth factor beta production protein binding involved in heterotypic cell-cell adhesion cell-cell adhesion cell-cell adhesion mediator activity cell-cell adhesion mediator activity positive regulation of arginase activity positive regulation of protein-glutamine gamma-glutamyltransferase activity regulation of neuroinflammatory response negative regulation of neuroinflammatory response negative regulation of neuroinflammatory response negative regulation of neuroinflammatory response negative regulation of matrix metallopeptidase secretion negative regulation of macrophage migration negative regulation of T cell migration |
|
| 1416915_at |
Msh6 |
mutS homolog 6 |
17 |
87975049 |
U42190 |
17688 |
81 |
nucleotide binding magnesium ion binding four-way junction DNA binding chromatin DNA binding DNA binding chromatin binding damaged DNA binding damaged DNA binding double-stranded DNA binding ATP binding nucleus nucleus nucleoplasm chromosome Golgi apparatus cytosol DNA repair mismatch repair mismatch repair mismatch repair mismatch repair DNA damage response ATP-dependent activity, acting on DNA determination of adult lifespan intrinsic apoptotic signaling pathway in response to DNA damage response to UV somatic hypermutation of immunoglobulin genes somatic recombination of immunoglobulin gene segments enzyme binding mismatched DNA binding mismatched DNA binding guanine/thymine mispair binding guanine/thymine mispair binding single guanine insertion binding single thymine insertion binding MutSalpha complex MutSalpha complex MutSalpha complex oxidized purine DNA binding MutLalpha complex binding methylated histone binding intracellular membrane-bounded organelle ADP binding isotype switching isotype switching negative regulation of DNA recombination negative regulation of DNA recombination positive regulation of helicase activity intrinsic apoptotic signaling pathway ATP-dependent DNA damage sensor activity |
03430 05200 05210 |
| 1422557_s_at |
Mt1 |
metallothionein 1 |
8 |
94179088 |
NM_013602 |
17748 |
343 |
copper ion binding nucleus nucleus cytoplasm cytoplasm lysosome cytosol cytosol intracellular zinc ion homeostasis intracellular zinc ion homeostasis nitric oxide mediated signal transduction zinc ion binding zinc ion binding detoxification of copper ion detoxification of copper ion intracellular monoatomic cation homeostasis negative regulation of neuron apoptotic process metal ion binding metal ion binding cellular response to chromate cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion cellular response to zinc ion |
|
| 1428942_at |
Mt2 |
metallothionein 2 |
8 |
94172617 |
AA796766 |
17750 |
223 |
nucleus nucleus cytoplasm cytoplasm cytosol intracellular zinc ion homeostasis intracellular zinc ion homeostasis nitric oxide mediated signal transduction zinc ion binding zinc ion binding response to bacterium detoxification of copper ion detoxification of copper ion cadmium ion binding metal ion binding metal ion binding cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion |
|
| 1419254_at |
Mthfd2 |
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase |
6 |
-83305703 |
BG076333 |
17768 |
45 |
magnesium ion binding catalytic activity methenyltetrahydrofolate cyclohydrolase activity methenyltetrahydrofolate cyclohydrolase activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity mitochondrion mitochondrion mitochondrion one-carbon metabolic process metabolic process oxidoreductase activity hydrolase activity tetrahydrofolate interconversion phosphate ion binding tetrahydrofolate metabolic process |
00670 01100 |
| 1451905_a_at |
Mx1 |
MX dynamin-like GTPase 1 |
16 |
-97447036, -97447034 |
M21039 |
17857 |
124 |
GTPase activity protein binding GTP binding GTP binding nucleus nucleus nuclear pore cytoplasm cytosol response to virus nuclear membrane identical protein binding innate immune response perinuclear region of cytoplasm |
|
| 1450194_a_at |
Myb |
myeloblastosis oncogene |
10 |
-21124929 |
NM_033597 |
17863 |
343 |
G1/S transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II mitotic cell cycle RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific in utero embryonic development DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytosol cytosol regulation of DNA-templated transcription regulation of DNA-templated transcription calcium ion transport regulation of gene expression stem cell division myeloid cell differentiation B cell differentiation erythrocyte differentiation positive regulation of collagen biosynthetic process positive regulation of neuron apoptotic process T-helper 2 cell differentiation negative regulation of megakaryocyte differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II spleen development thymus development embryonic digestive tract development positive regulation of smooth muscle cell proliferation homeostasis of number of cells positive regulation of glial cell proliferation myeloid cell development cellular response to interleukin-6 positive regulation of transforming growth factor beta production WD40-repeat domain binding RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex negative regulation of hematopoietic progenitor cell differentiation positive regulation of miRNA transcription positive regulation of hepatic stellate cell proliferation cellular response to leukemia inhibitory factor positive regulation of hepatic stellate cell activation positive regulation of testosterone secretion |
|
| 1419272_at |
Myd88 |
myeloid differentiation primary response gene 88 |
9 |
-119335933 |
BC005591 |
17874 |
2408 |
response to molecule of fungal origin leukocyte activation involved in inflammatory response neutrophil activation involved in immune response immune system process MyD88-dependent toll-like receptor signaling pathway MyD88-dependent toll-like receptor signaling pathway signaling receptor binding Toll binding interleukin-1 receptor binding interleukin-1 receptor binding protein binding nucleus cytoplasm cytoplasm cytosol plasma membrane plasma membrane plasma membrane chromatin organization phagocytosis phagocytosis apoptotic process inflammatory response immune response signal transduction cell surface receptor signaling pathway transmembrane receptor protein serine/threonine kinase signaling pathway JNK cascade JNK cascade Toll signaling pathway Toll signaling pathway response to virus induced systemic resistance cell surface gene expression regulation of gene expression positive regulation of gene expression positive regulation of gene expression macrophage cytokine production macrophage cytokine production microglia differentiation immunoglobulin mediated immune response cytokine-mediated signaling pathway extrinsic component of plasma membrane neurogenesis extrinsic component of cytoplasmic side of plasma membrane lipopolysaccharide-mediated signaling pathway positive regulation of type I interferon production response to peptidoglycan response to lipopolysaccharide response to lipopolysaccharide chemokine production type I interferon production interleukin-6 production tumor necrosis factor production tumor necrosis factor production regulation of interleukin-6 production regulation of tumor necrosis factor production positive regulation of chemokine production positive regulation of interleukin-1 beta production positive regulation of interleukin-17 production positive regulation of interleukin-23 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production protein-containing complex toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway toll-like receptor 8 signaling pathway Toll-like receptor binding Toll-like receptor binding signaling adaptor activity signaling adaptor activity interleukin-33-mediated signaling pathway regulation of cell population proliferation defense response to bacterium identical protein binding defense response to protozoan positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction skin development protein self-association innate immune response innate immune response positive regulation of transcription by RNA polymerase II positive regulation of JNK cascade positive regulation of smooth muscle cell proliferation positive regulation of lymphocyte proliferation regulation of inflammatory response defense response to Gram-positive bacterium defense response to Gram-positive bacterium positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity defense response to virus molecular adaptor activity type I interferon-mediated signaling pathway positive regulation of macrophage cytokine production positive regulation of macrophage cytokine production interleukin-1-mediated signaling pathway interleukin-1-mediated signaling pathway response to interleukin-1 3'-UTR-mediated mRNA stabilization neutrophil-mediated killing of bacterium TIR domain binding cellular response to lipopolysaccharide cellular response to organic substance establishment of endothelial intestinal barrier cellular response to oxidised low-density lipoprotein particle stimulus ATP-dependent histone chaperone activity positive regulation of cytokine production involved in inflammatory response positive regulation of cytokine production involved in inflammatory response positive regulation of NLRP3 inflammasome complex assembly regulation of neutrophil migration regulation of chemokine (C-X-C motif) ligand 1 production regulation of chemokine (C-X-C motif) ligand 2 production |
04210 04620 05140 05142 05143 05144 05145 |
| 1422580_at |
Myl4 |
myosin, light polypeptide 4 |
11 |
104577280, 104550662, 104576984 |
NM_010858 |
17896 |
93 |
regulation of the force of heart contraction actin monomer binding actin monomer binding calcium ion binding myosin complex myosin II complex A band A band positive regulation of ATP-dependent activity actin filament binding cardiac muscle contraction cardiac muscle contraction |
|
| 1449550_at |
Myo1c |
myosin IC |
11 |
75656014, 75651508, 75652149, 75650518 |
NM_008659 |
17913 |
86 |
microfilament motor activity microfilament motor activity microfilament motor activity nucleotide binding cytoskeletal motor activity actin binding signaling receptor binding protein binding calmodulin binding calmodulin binding ATP binding phospholipid binding nucleus nucleolus cytoplasm cytoplasm cytosol plasma membrane plasma membrane plasma membrane microvillus microvillus brush border chromatin remodeling protein targeting to membrane endocytosis actin filament organization basal plasma membrane actin cytoskeleton membrane membrane lateral plasma membrane myosin complex nuclear body actin filament-based movement vesicle transport along actin filament positive regulation of cell migration cytoplasmic vesicle membrane positive regulation of actin filament polymerization small GTPase binding cytoplasmic vesicle filamentous actin stereocilium stereocilium bundle ruffle membrane positive regulation of cell migration by vascular endothelial growth factor signaling pathway cell projection membrane raft phagocytic vesicle positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase III actin filament binding actin filament binding cellular response to type II interferon positive regulation of protein targeting to membrane positive regulation of protein targeting to membrane positive regulation of protein targeting to membrane B-WICH complex positive regulation of cellular response to insulin stimulus positive regulation of cellular response to insulin stimulus positive regulation of cellular response to insulin stimulus positive regulation of vascular endothelial growth factor signaling pathway regulation of bicellular tight junction assembly |
|
| 1460273_a_at |
Naip2 |
NLR family, apoptosis inhibitory protein 2 |
13 |
-100144062 |
NM_010872 |
17948 |
26 |
nucleotide binding immune system process protein binding ATP binding ATP binding apoptotic process inflammatory response inflammatory response negative regulation of tumor necrosis factor-mediated signaling pathway detection of bacterium detection of bacterium defense response to bacterium defense response to bacterium regulation of apoptotic process neuronal cell body cysteine-type endopeptidase inhibitor activity involved in apoptotic process cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process perikaryon innate immune response positive regulation of JNK cascade metal ion binding pyroptosis pyroptosis cellular response to estrogen stimulus IPAF inflammasome complex IPAF inflammasome complex protein serine/threonine kinase binding |
04621 |
| 1425609_at |
Ncf1 |
neutrophil cytosolic factor 1 |
5 |
-134220258, -134220052 |
BE370703 |
17969 |
363 |
response to yeast leukocyte mediated cytotoxicity respiratory burst involved in defense response protein binding cytoplasm cytoplasm cytosol cytosol plasma membrane leukotriene metabolic process NADP catabolic process smooth muscle contraction inflammatory response cellular defense response lipid binding response to bacterium cytoplasmic side of plasma membrane membrane membrane superoxide-generating NAD(P)H oxidase activity superoxide-generating NADPH oxidase activator activity superoxide-generating NADPH oxidase activator activity superoxide-generating NADPH oxidase activator activity superoxide-generating NADPH oxidase activator activity SH3 domain binding dendrite phosphatidylinositol binding superoxide anion generation superoxide anion generation defense response to bacterium NADPH oxidase complex NADPH oxidase complex neuronal cell body phosphatidylinositol-3,4-bisphosphate binding respiratory burst respiratory burst respiratory burst negative regulation of smooth muscle contraction hydrogen peroxide biosynthetic process epithelial cell proliferation defense response to Gram-positive bacterium defense response to fungus regulation of respiratory burst involved in inflammatory response neutrophil-mediated killing of gram-positive bacterium neutrophil-mediated killing of fungus reactive oxygen species biosynthetic process |
04062 04145 04380 04666 04670 05140 |
| 1418465_at |
Ncf4 |
neutrophil cytosolic factor 4 |
15 |
78244810 |
NM_008677 |
17972 |
42 |
protein binding cytoplasm cytoplasm endosome cytosol phagocytosis lipid binding endosome membrane membrane superoxide-generating NADPH oxidase activator activity superoxide-generating NADPH oxidase activator activity phosphatidylinositol-3-phosphate binding phosphatidylinositol binding superoxide anion generation superoxide anion generation NADPH oxidase complex NADPH oxidase complex respiratory burst |
04145 04380 04670 05140 |
| 1428479_at |
Nfatc1 |
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 |
18 |
-80606204, -80647434, -80647434, -80606204 |
BB356861 |
18018 |
536 |
G1/S transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription coactivator binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific cytokine production epithelial to mesenchymal transition lymphangiogenesis B-1a B cell differentiation heart valve development aortic valve development pulmonary valve development heart valve morphogenesis aortic valve morphogenesis pulmonary valve morphogenesis endocardial cushion development nucleic acid binding DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm transcription regulator complex transcription regulator complex cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II calcium ion transport heart development transcription factor binding gene expression positive regulation of gene expression negative regulation of keratinocyte proliferation transition between fast and slow fiber sarcoplasm nuclear body osteoclast differentiation calcineurin-NFAT signaling cascade calcineurin-NFAT signaling cascade calcineurin-NFAT signaling cascade intracellular signal transduction wound healing regulation of hair cycle sequence-specific DNA binding keratinocyte proliferation cell quiescence negative regulation of osteoblast differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II mitogen-activated protein kinase p38 binding perinuclear region of cytoplasm ventricular septum morphogenesis branching involved in lymph vessel morphogenesis heart trabecula morphogenesis RNA polymerase II-specific DNA-binding transcription factor binding cellular response to calcium ion stem cell proliferation DNA-binding transcription factor binding negative regulation of vascular associated smooth muscle cell differentiation semi-lunar valve development sequence-specific double-stranded DNA binding positive regulation of DNA biosynthetic process negative regulation of stem cell proliferation |
04310 04360 04370 04380 04650 04660 04662 |
| 1434836_at |
Nfatc2ip |
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein |
7 |
-126382853 |
AV277440 |
18020 |
29 |
cytokine production cytokine production protein binding nucleus cytoplasm positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II |
|
| 1419976_s_at |
Nfatc3 |
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 |
8 |
106059589, 106058817 |
C79787 |
18021 |
160 |
transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific branching involved in blood vessel morphogenesis response to hypoxia cytokine production blood vessel remodeling DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm transcription regulator complex cytoplasm cytoplasm cytosol cytosol regulation of DNA-templated transcription regulation of transcription by RNA polymerase II transcription by RNA polymerase II multicellular organism development heart development transcription factor binding transcription factor binding cardiac muscle hypertrophy in response to stress myotube differentiation myotube cell development T cell differentiation calcineurin-NFAT signaling cascade calcineurin-NFAT signaling cascade vascular associated smooth muscle cell differentiation sequence-specific DNA binding positive thymic T cell selection cellular respiration positive regulation of nitric oxide biosynthetic process positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II thymus development skeletal muscle fiber development cellular response to calcium ion cellular response to lithium ion vascular associated smooth muscle cell development negative regulation of miRNA transcription DN4 thymocyte differentiation negative regulation of vascular associated smooth muscle cell differentiation positive regulation of artery morphogenesis sequence-specific double-stranded DNA binding regulation of store-operated calcium entry |
04310 04360 04370 04650 04660 04662 |
| 1416543_at |
Nfe2l2 |
nuclear factor, erythroid derived 2, like 2 |
2 |
-75675512, -75691051 |
NM_010902 |
18024 |
1716 |
chromatin transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific transcription coregulator binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex cytoplasm cytoplasm cytoplasm cytoplasm Golgi apparatus centrosome cytosol cytosol cytosol plasma membrane regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II inflammatory response response to oxidative stress transcription factor binding response to organic substance proteasomal ubiquitin-independent protein catabolic process positive regulation of gene expression positive regulation of gene expression negative regulation of cardiac muscle cell apoptotic process positive regulation of neuron projection development protein ubiquitination protein domain specific binding positive regulation of blood coagulation endoplasmic reticulum unfolded protein response ubiquitin protein ligase binding protein-DNA complex cellular response to oxidative stress cellular response to oxidative stress cellular response to oxidative stress response to endoplasmic reticulum stress PERK-mediated unfolded protein response cellular response to glucose starvation proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of blood vessel endothelial cell migration sequence-specific DNA binding sequence-specific DNA binding regulation of innate immune response cell redox homeostasis cell redox homeostasis positive regulation of angiogenesis positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of embryonic development aflatoxin catabolic process positive regulation of glucose import RNA polymerase II-specific DNA-binding transcription factor binding cellular response to hydrogen peroxide cellular response to copper ion cellular response to tumor necrosis factor cellular response to hypoxia cellular response to xenobiotic stimulus cellular response to fluid shear stress cellular response to laminar fluid shear stress RNA polymerase II transcription regulator complex negative regulation of cellular response to hypoxia regulation of cellular response to oxidative stress negative regulation of hematopoietic stem cell differentiation negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway positive regulation of glutathione biosynthetic process cellular response to angiotensin negative regulation of vascular associated smooth muscle cell migration regulation of removal of superoxide radicals negative regulation of endothelial cell apoptotic process positive regulation of reactive oxygen species metabolic process |
04141 |
| 1418932_at |
Nfil3 |
nuclear factor, interleukin 3, regulated |
13 |
-52967208 |
AY061760 |
18030 |
130 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific natural killer cell differentiation DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus DNA-templated transcription regulation of DNA-templated transcription regulation of DNA-templated transcription transcription by RNA polymerase II immune response circadian rhythm circadian rhythm positive regulation of gene expression positive regulation of gene expression identical protein binding negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription rhythmic process cellular response to interleukin-4 RNA polymerase II transcription regulator complex |
|
| 1418722_at |
Ngp |
neutrophilic granule protein |
9 |
110419807 |
NM_008694 |
18054 |
22 |
cysteine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity extracellular region extracellular space extracellular space defense response negative regulation of peptidase activity negative regulation of angiogenesis peptidase inhibitor activity cytoplasmic vesicle negative regulation of lymphangiogenesis |
|
| 1448465_at |
Nipsnap1 |
nipsnap homolog 1 |
11 |
4873950 |
BC010837 |
18082 |
31 |
protein binding protein binding mitochondrion mitochondrion mitochondrion mitochondrial inner membrane membrane sensory perception of pain sensory perception of pain synaptic membrane |
|
| 1456573_x_at |
Nnt |
nicotinamide nucleotide transhydrogenase |
13 |
-119335526, -119334316 |
BB205930 |
18115 |
75 |
negative regulation of protein phosphorylation mitochondrion mitochondrion mitochondrial inner membrane NADPH regeneration NADPH regeneration NAD(P)+ transhydrogenase activity NAD(P)+ transhydrogenase activity positive regulation of mitochondrial membrane potential membrane oxidoreductase activity intracellular oxygen homeostasis negative regulation of apoptotic process cell redox homeostasis NADP binding NADP binding reactive oxygen species metabolic process cellular oxidant detoxification proton transmembrane transport positive regulation of hydrogen peroxide catabolic process |
00760 01100 |
| 1426851_a_at |
Ccn3 |
cellular communication network factor 3 |
15 |
54745909 |
X96585 |
18133 |
75 |
angiogenesis chondrocyte differentiation chondrocyte differentiation Notch binding integrin binding integrin binding extracellular region extracellular space extracellular space cytoplasm gap junction cell adhesion signal transduction signal transduction growth factor activity heparin binding regulation of gene expression fibroblast migration negative regulation of myotube differentiation smooth muscle cell migration negative regulation of cell growth axon dendrite extracellular matrix cell adhesion mediated by integrin endothelial cell chemotaxis neuronal cell body intracellular membrane-bounded organelle type B pancreatic cell proliferation positive regulation of cell differentiation positive regulation of Notch signaling pathway negative regulation of insulin secretion smooth muscle cell proliferation smooth muscle cell proliferation negative regulation of inflammatory response cell chemotaxis negative regulation of SMAD protein signal transduction hematopoietic stem cell homeostasis collagen-containing extracellular matrix anchoring junction endothelial cell-cell adhesion negative regulation of monocyte chemotaxis negative regulation of non-canonical NF-kappaB signal transduction negative regulation of chondrocyte proliferation negative regulation of sensory perception of pain bone regeneration |
|
| 1415839_a_at |
Npm1 |
nucleophosmin 1 |
11 |
-33152497, -33154924 |
NM_008722 |
18148 |
183 |
ribosomal subunit export from nucleus ribosomal large subunit export from nucleus ribosomal large subunit export from nucleus ribosomal small subunit export from nucleus ribosomal small subunit export from nucleus cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) core promoter sequence-specific DNA binding regulation of cell growth granular component p53 binding nucleic acid binding DNA binding chromatin binding transcription coactivator activity RNA binding RNA binding RNA binding protein kinase inhibitor activity protein binding ATP binding phosphatidylinositol-3,4,5-trisphosphate binding nucleus nucleus nucleoplasm nucleoplasm nucleoplasm nucleolus nucleolus nucleolus cytoplasm cytoplasm cytoplasm centrosome centrosome centrosome cytosol cytoskeleton DNA repair nucleosome assembly chromatin remodeling cell volume homeostasis cell volume homeostasis nucleocytoplasmic transport nucleocytoplasmic transport centrosome cycle protein localization protein localization positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation rRNA transcription post-transcriptional regulation of gene expression negative regulation of gene expression negative regulation of cardiac muscle cell apoptotic process regulation of centrosome duplication regulation of centrosome duplication positive regulation of centrosome duplication negative regulation of centrosome duplication large ribosomal subunit small ribosomal subunit nuclear matrix nuclear speck rRNA binding rRNA binding enzyme binding protein kinase binding Tat protein binding positive regulation of cellular biosynthetic process positive regulation of cellular biosynthetic process positive regulation of protein ubiquitination spindle pole centrosome regulation of protein stability protein destabilization regulation of endodeoxyribonuclease activity protein-containing complex protein-DNA complex cellular response to UV ribosomal large subunit biogenesis ribosomal large subunit biogenesis ribosomal large subunit biogenesis ribosomal small subunit biogenesis ribosomal small subunit biogenesis ribosomal small subunit biogenesis histone binding histone binding identical protein binding identical protein binding protein homodimerization activity ribosomal large subunit binding ribosomal small subunit binding negative regulation of apoptotic process negative regulation of apoptotic process protein kinase B binding regulation of DNA damage response, signal transduction by p53 class mediator regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of protein kinase activity by regulation of protein phosphorylation positive regulation of translation positive regulation of DNA replication positive regulation of protein kinase activity positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of centriole replication negative regulation of mRNA splicing, via spliceosome negative regulation of epithelial cell proliferation protein stabilization protein stabilization positive regulation of DNA metabolic process NF-kappaB binding unfolded protein binding positive regulation of NF-kappaB transcription factor activity regulation of cell cycle regulation of endoribonuclease activity regulation of eIF2 alpha phosphorylation by dsRNA cellular senescence DNA-binding transcription factor binding molecular condensate scaffold activity regulation of mRNA stability involved in cellular response to UV positive regulation of cell cycle G2/M phase transition positive regulation of protein localization to nucleolus positive regulation of protein localization to nucleolus ribonucleoprotein complex ribonucleoprotein complex |
|
| 1420361_at |
Slc11a1 |
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 |
1 |
74375202 |
NM_013612 |
18173 |
249 |
negative regulation of cytokine production positive regulation of cytokine production T cell proliferation involved in immune response T cell cytokine production positive regulation of dendritic cell antigen processing and presentation positive regulation of T-helper 1 type immune response iron ion transmembrane transporter activity iron ion transmembrane transporter activity iron ion transmembrane transporter activity manganese ion transmembrane transporter activity manganese ion transmembrane transporter activity manganese ion transmembrane transporter activity manganese ion transmembrane transporter activity lysosome lysosomal membrane lysosomal membrane endosome late endosome late endosome plasma membrane plasma membrane monoatomic ion transport iron ion transport iron ion transport manganese ion transport manganese ion transport manganese ion transport manganese ion transport intracellular iron ion homeostasis intracellular iron ion homeostasis phagocytosis inflammatory response vacuolar acidification response to bacterium response to bacterium endosome membrane endosome membrane positive regulation of gene expression cadmium ion transmembrane transporter activity nitrite transport membrane metal ion transport phagocytic vesicle membrane phagocytic vesicle membrane phagocytic vesicle membrane phagocytic vesicle membrane late endosome membrane activation of protein kinase activity response to lipopolysaccharide response to lipopolysaccharide response to lipopolysaccharide type II interferon production interleukin-2 production interleukin-3 production positive regulation of type II interferon production response to type II interferon iron ion transmembrane transport wound healing macrophage activation macrophage activation defense response to bacterium protein homodimerization activity defense response to protozoan MHC class II biosynthetic process respiratory burst positive regulation of transcription by RNA polymerase II metal ion transmembrane transporter activity transition metal ion transmembrane transporter activity antigen processing and presentation of peptide antigen mRNA stabilization positive regulation of phagocytosis defense response to Gram-negative bacterium metal cation:proton antiporter activity metal cation:proton antiporter activity metal cation:proton antiporter activity establishment of localization in cell multicellular organismal-level iron ion homeostasis cadmium ion transmembrane transport tertiary granule membrane cellular detoxification of cadmium ion L-arginine transmembrane transport |
04142 |
| 1435088_at |
Nsd1 |
nuclear receptor-binding SET-domain protein 1 |
13 |
55209781 |
BM945177 |
18193 |
58 |
negative regulation of transcription by RNA polymerase II chromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding gastrulation with mouth forming second chromatin binding transcription coregulator activity transcription coregulator activity transcription corepressor activity protein binding nucleus nucleus nucleus chromosome chromatin organization regulation of DNA-templated transcription regulation of DNA-templated transcription multicellular organism development methyltransferase activity zinc ion binding transferase activity nuclear estrogen receptor binding methylation regulation of peptidyl-serine phosphorylation histone methyltransferase complex histone methyltransferase activity histone H4K20 methyltransferase activity nuclear retinoic acid receptor binding positive regulation of DNA-templated transcription metal ion binding nuclear retinoid X receptor binding nuclear thyroid hormone receptor binding histone H3K36 methyltransferase activity histone H3K36 methyltransferase activity histone H3K36 methyltransferase activity nuclear androgen receptor binding histone H3K36 dimethyltransferase activity regulation of RNA polymerase II regulatory region sequence-specific DNA binding |
00310 |
| 1416107_at |
Nsg2 |
neuron specific gene family member 2 |
11 |
32001276, 32000699, 32000418, 32000418 |
NM_008741 |
18197 |
25 |
lysosome endosome endosome early endosome late endosome Golgi apparatus dopamine receptor signaling pathway membrane endosomal transport dendrite cytoplasmic vesicle membrane cytoplasmic vesicle clathrin light chain binding clathrin light chain binding multivesicular body membrane trans-Golgi network membrane cell projection lysosomal lumen clathrin coat assembly clathrin coat assembly Golgi cis cisterna membrane |
|
| 1451054_at |
Orm1 |
orosomucoid 1 |
4 |
63344555 |
BE628912 |
18405 |
62 |
regulation of immune system process extracellular region extracellular space extracellular space acute-phase response small molecule binding |
|
| 1420967_at |
Slc25a15 |
solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15 |
8 |
-22375549, -22375549 |
AW541300 |
18408 |
20 |
L-ornithine transmembrane transporter activity L-ornithine transmembrane transporter activity mitochondrion mitochondrion mitochondrion mitochondrial inner membrane L-lysine transmembrane transporter activity antiporter activity membrane L-arginine transmembrane transporter activity L-lysine transmembrane transport L-arginine transmembrane transport mitochondrial L-ornithine transmembrane transport |
|
| 1421456_at |
P2ry1 |
purinergic receptor P2Y, G-protein coupled 1 |
3 |
61002784 |
NM_008772 |
18441 |
124 |
nucleotide binding G protein-coupled ADP receptor activity G protein-coupled ADP receptor activity positive regulation of protein phosphorylation G protein-coupled adenosine receptor signaling pathway G protein-coupled receptor activity ATP binding ATP binding plasma membrane plasma membrane plasma membrane cilium monoatomic ion transport monoatomic ion transport signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration glial cell migration regulation of cell shape response to mechanical stimulus negative regulation of norepinephrine secretion postsynaptic density membrane basolateral plasma membrane apical plasma membrane signal transduction involved in regulation of gene expression platelet activation dendrite A1 adenosine receptor binding A1 adenosine receptor binding positive regulation of inositol trisphosphate biosynthetic process G protein-coupled purinergic nucleotide receptor signaling pathway eating behavior positive regulation of monoatomic ion transport positive regulation of monoatomic ion transport ADP binding cell body G protein-coupled purinergic nucleotide receptor activity G protein-coupled ATP receptor activity G protein-coupled ATP receptor activity postsynaptic membrane positive regulation of transcription by RNA polymerase II positive regulation of hormone secretion protein heterodimerization activity presynaptic active zone membrane establishment of localization in cell establishment of localization in cell positive regulation of penile erection positive regulation of ERK1 and ERK2 cascade cellular response to organic cyclic compound cellular response to purine-containing compound protein localization to plasma membrane relaxation of muscle scaffold protein binding blood vessel diameter maintenance glutamatergic synapse regulation of presynaptic cytosolic calcium ion concentration regulation of synaptic vesicle exocytosis |
04080 |
| 1416410_at |
Pafah1b3 |
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3 |
7 |
-25295048, -25295048 |
NM_008776 |
18476 |
37 |
1-alkyl-2-acetylglycerophosphocholine esterase activity protein binding cytoplasm cytoplasm lipid metabolic process spermatogenesis spermatogenesis 1-alkyl-2-acetylglycerophosphocholine esterase complex lipid catabolic process hydrolase activity identical protein binding protein homodimerization activity protein-containing complex binding protein heterodimerization activity platelet-activating factor acetyltransferase activity platelet-activating factor acetyltransferase activity |
00565 01100 |
| 1454638_a_at |
Pah |
phenylalanine hydroxylase |
10 |
87521794 |
AW106920 |
18478 |
125 |
catalytic activity monooxygenase activity phenylalanine 4-monooxygenase activity phenylalanine 4-monooxygenase activity phenylalanine 4-monooxygenase activity iron ion binding L-phenylalanine metabolic process L-phenylalanine catabolic process tyrosine biosynthetic process tyrosine biosynthetic process metabolic process aromatic amino acid metabolic process oxidoreductase activity amino acid binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen tyrosine biosynthetic process, by oxidation of phenylalanine tyrosine biosynthetic process, by oxidation of phenylalanine identical protein binding metal ion binding |
00360 00400 01100 |
| 1420979_at |
Pak1 |
p21 (RAC1) activated kinase 1 |
7 |
97842938, 97788540 |
BF456404 |
18479 |
224 |
nucleotide binding response to hypoxia ruffle positive regulation of protein phosphorylation catalytic activity protein kinase activity protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding collagen binding ATP binding nucleus nucleoplasm chromosome cytoplasm cytoplasm cytoplasm cytosol cytoskeleton actin filament plasma membrane cell-cell junction focal adhesion chromatin remodeling protein phosphorylation protein phosphorylation exocytosis apoptotic process DNA damage response neuromuscular junction development metabolic process positive regulation of cell population proliferation response to organic substance regulation of gene expression positive regulation of fibroblast migration postsynaptic density postsynaptic density intercalated disc membrane kinase activity phosphorylation dendrite development cell migration transferase activity transmission of nerve impulse protein kinase binding amygdala development establishment of cell polarity Z disc lamellipodium actin cytoskeleton organization positive regulation of cell migration axon axon dendrite dendrite growth cone positive regulation of microtubule polymerization small GTPase binding nuclear membrane cellular response to insulin stimulus regulation of actin cytoskeleton organization regulation of actin cytoskeleton organization protein-containing complex positive regulation of peptidyl-serine phosphorylation positive regulation of intracellular estrogen receptor signaling pathway intracellular signal transduction wound healing identical protein binding cell projection gamma-tubulin binding receptor clustering regulation of MAPK cascade regulation of MAPK cascade positive regulation of JUN kinase activity positive regulation of axon extension positive regulation of insulin receptor signaling pathway protein autophosphorylation hepatocyte growth factor receptor signaling pathway branching morphogenesis of an epithelial tube neuron projection morphogenesis regulation of axonogenesis localization positive regulation of stress fiber assembly negative regulation of cell proliferation involved in contact inhibition dendritic spine development negative regulation of cell growth involved in cardiac muscle cell development gamma-aminobutyric acid secretion, neurotransmission glutamate secretion, neurotransmission anchoring junction cellular response to organic cyclic compound positive regulation of microtubule nucleation positive regulation of protein targeting to membrane observational learning glutamatergic synapse glutamatergic synapse glutamatergic synapse GABA-ergic synapse GABA-ergic synapse GABA-ergic synapse GABA-ergic synapse regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission regulation of long-term synaptic potentiation protein localization to cytoplasmic stress granule positive regulation of vascular associated smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell migration |
04010 04012 04062 04360 04510 04650 04660 04666 04810 05211 |
| 1458978_at |
Pax5 |
paired box 5 |
4 |
-44524750 |
BG144033 |
18507 |
229 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm transcription regulator complex regulation of DNA-templated transcription regulation of transcription by RNA polymerase II multicellular organism development spermatogenesis nervous system development animal organ morphogenesis lateral ventricle development cerebral cortex development cell differentiation adult behavior skeletal muscle cell differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II embryonic cranial skeleton morphogenesis anatomical structure development dopaminergic neuron differentiation |
|
| 1418840_at |
Pdcd4 |
programmed cell death 4 |
19 |
53903350, 53892230 |
NM_011050 |
18569 |
101 |
RNA binding protein binding nucleus nucleus cytoplasm cytosol cytosol apoptotic process BMP signaling pathway positive regulation of smooth muscle cell apoptotic process negative regulation of apoptotic process negative regulation of DNA-templated transcription positive regulation of inflammatory response regulation of protein metabolic process epithelial to mesenchymal transition involved in cardiac fibroblast development cellular response to lipopolysaccharide negative regulation of cytokine production involved in inflammatory response positive regulation of non-canonical NF-kappaB signal transduction negative regulation of vascular associated smooth muscle cell proliferation negative regulation of myofibroblast differentiation negative regulation of vascular associated smooth muscle cell differentiation positive regulation of vascular associated smooth muscle cell apoptotic process positive regulation of endothelial cell apoptotic process |
|
| 1422474_at |
Pde4b |
phosphodiesterase 4B, cAMP specific |
4 |
102589842, 102254938, 102254741, 102570059, 102587557, 102421554 |
BM246564 |
18578 |
79 |
gamma-tubulin complex neutrophil homeostasis 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity calcium channel regulator activity protein binding nucleus centrosome cytosol cytosol voltage-gated calcium channel complex synaptic vesicle postsynaptic density membrane cAMP-mediated signaling Z disc cAMP binding neutrophil chemotaxis positive regulation of type II interferon production positive regulation of interleukin-2 production gamma-tubulin binding dendritic spine transmembrane transporter binding transmembrane transporter binding 3',5'-cyclic-GMP phosphodiesterase activity perinuclear region of cytoplasm perinuclear region of cytoplasm T cell receptor signaling pathway leukocyte migration excitatory synapse cellular response to lipopolysaccharide cellular response to xenobiotic stimulus cellular response to epinephrine stimulus negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway cell periphery regulation of cardiac muscle cell contraction negative regulation of relaxation of cardiac muscle regulation of calcium ion transmembrane transport via high voltage-gated calcium channel |
00230 |
| 1458218_s_at |
Pde7a |
phosphodiesterase 7A |
3 |
-19223108, -19223108 |
AU015378 |
18583 |
30 |
cyclic-nucleotide phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity nucleus cytoplasm cytosol signal transduction phosphoric diester hydrolase activity hydrolase activity cAMP-mediated signaling cAMP-mediated signaling cAMP-mediated signaling metal ion binding 3',5'-cyclic-GMP phosphodiesterase activity perinuclear region of cytoplasm |
00230 |
| 1422760_at |
Padi4 |
peptidyl arginine deiminase, type IV |
4 |
-140745507 |
NM_011061 |
18602 |
120 |
immune system process protein-arginine deiminase activity protein-arginine deiminase activity protein-arginine deiminase activity calcium ion binding nucleus nucleus cytoplasm cytoplasm chromatin organization nucleosome assembly chromatin remodeling chromatin remodeling hydrolase activity stem cell population maintenance protein-containing complex identical protein binding post-translational protein modification innate immune response metal ion binding histone arginine deiminase activity histone arginine deiminase activity histone H3R2 arginine deiminase activity histone H3R8 arginine deiminase activity histone H3R17 arginine deiminase activity histone H3R26 arginine deiminase activity |
|
| 1419276_at |
Enpp1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
10 |
-24637913 |
AF339910 |
18605 |
147 |
cell morphogenesis cell morphogenesis ossification vasculogenesis osteoblast differentiation osteoblast differentiation kidney development B-1 B cell homeostasis endochondral ossification morphogenesis of an epithelium response to dietary excess leukocyte activation involved in inflammatory response plasma cell differentiation immunoglobulin production involved in immunoglobulin-mediated immune response inflammatory response to antigenic stimulus nucleic acid binding exonuclease activity phosphodiesterase I activity phosphodiesterase I activity phosphodiesterase I activity phosphodiesterase I activity dinucleotide phosphatase activity dinucleotide phosphatase activity dinucleotide phosphatase activity scavenger receptor activity insulin receptor binding calcium ion binding ATP binding extracellular region extracellular region extracellular space extracellular space extracellular space plasma membrane plasma membrane generation of precursor metabolites and energy glycolytic process fatty acid metabolic process phosphate-containing compound metabolic process nitrogen compound metabolic process immune response mitochondrion organization smoothened signaling pathway heart development sensory perception of sound adult walking behavior phosphoric diester hydrolase activity zinc ion binding cell population proliferation cell population proliferation determination of adult lifespan adult locomotory behavior fibroblast growth factor receptor signaling pathway nucleoside triphosphate catabolic process nucleoside triphosphate catabolic process response to wounding cell surface cell surface cell surface response to inorganic substance gene expression gene expression gene expression gene expression coenzyme A diphosphatase activity magnesium ion homeostasis microglia differentiation coenzyme A catabolic process coenzyme A catabolic process membrane Wnt signaling pathway pyrophosphatase activity hydrolase activity phosphatase activity phosphatase activity phosphatase activity organic phosphonate metabolic process cellular homeostasis cellular homeostasis spinal cord development central nervous system myelination T cell differentiation macrophage differentiation polysaccharide binding negative regulation of ossification bone mineralization bone mineralization bone mineralization bone mineralization negative regulation of cell growth osteoclast differentiation melanocyte differentiation regulation of bone mineralization negative regulation of bone mineralization inorganic diphosphate transport inorganic diphosphate transport inorganic diphosphate transport inorganic diphosphate transport inorganic diphosphate transport intracellular phosphate ion homeostasis sequestering of triglyceride axon regeneration biomineral tissue development negative regulation of protein autophosphorylation response to magnesium ion response to magnesium ion type II interferon production response to insulin cellular response to insulin stimulus response to ATP tooth mineralization response to vitamin B6 post-embryonic forelimb morphogenesis multicellular organism growth bone mineralization involved in bone maturation aorta development ligamentous ossification response to platelet-derived growth factor collagen-activated signaling pathway hormone metabolic process middle ear morphogenesis odontogenesis glucose homeostasis mRNA transcription by RNA polymerase II identical protein binding protein homodimerization activity protein homodimerization activity defense response to protozoan cell projection neuronal cell body skin development cell body fat cell differentiation bone resorption negative regulation of fat cell differentiation negative regulation of fat cell differentiation negative regulation of fat cell differentiation negative regulation of glycogen biosynthetic process ATP metabolic process ATP metabolic process ATP metabolic process glucose import negative regulation of glucose import negative regulation of insulin receptor signaling pathway muscle cell cellular homeostasis bone remodeling metal ion binding nucleoside triphosphate diphosphatase activity nucleoside triphosphate diphosphatase activity 3'-phosphoadenosine 5'-phosphosulfate metabolic process sensory perception of temperature stimulus sensory perception of mechanical stimulus cartilage development neuron apoptotic process establishment of localization in cell phosphate ion homeostasis phosphate ion homeostasis phosphate ion homeostasis phosphate ion homeostasis calcium ion homeostasis calcium ion homeostasis long-term synaptic potentiation bone trabecula formation bone development endochondral bone morphogenesis adipose tissue development fat pad development artery development articular cartilage development protein poly-ADP-ribosylation mucus secretion vitamin D3 metabolic process diphosphate metabolic process diphosphate metabolic process cementum mineralization cementum mineralization cementum mineralization nucleic acid metabolic process hematopoietic stem cell migration to bone marrow oligodendrocyte apoptotic process apical dendrite basal dendrite bone growth cyclic-GMP-AMP hydrolase activity cyclic-GMP-AMP hydrolase activity cyclic-GMP-AMP hydrolase activity response to Gram-positive bacterium inhibition of non-skeletal tissue mineralization inhibition of non-skeletal tissue mineralization inhibition of non-skeletal tissue mineralization inhibition of non-skeletal tissue mineralization apoptotic process involved in development microglial cell migration response to sodium phosphate response to sodium phosphate cellular response to sodium phosphate vascular associated smooth muscle cell migration negative regulation of hh target transcription factor activity vascular associated smooth muscle cell proliferation |
00230 00500 00740 00760 00770 01100 |
| 1452279_at |
Cfp |
complement factor properdin |
X |
-20925453 |
BB800282 |
18636 |
53 |
immune system process extracellular region extracellular space complement activation complement activation, alternative pathway secretory granule innate immune response positive regulation of immune response cytoplasmic side of Golgi membrane cytoplasmic side of Golgi membrane positive regulation of opsonization |
|
| 1418209_a_at |
Pfn2 |
profilin 2 |
3 |
-57841894 |
NM_019410 |
18645 |
64 |
actin binding actin binding actin monomer binding protein binding phosphatidylinositol-4,5-bisphosphate binding cytoplasm cytoplasm cytosol cytoskeleton negative regulation of epithelial cell migration negative regulation of epithelial cell migration ATP hydrolysis activity actin cytoskeleton organization regulation of actin filament polymerization regulation of actin filament polymerization negative regulation of actin filament polymerization positive regulation of actin filament polymerization positive regulation of actin filament polymerization positive regulation of actin filament bundle assembly positive regulation of actin filament bundle assembly positive regulation of ATP-dependent activity positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation modulation of chemical synaptic transmission modulation of chemical synaptic transmission protein stabilization positive regulation of stress fiber assembly positive regulation of stress fiber assembly Schaffer collateral - CA1 synapse presynapse postsynapse modification of postsynaptic actin cytoskeleton modification of postsynaptic actin cytoskeleton glutamatergic synapse glutamatergic synapse presynaptic modulation of chemical synaptic transmission presynaptic modulation of chemical synaptic transmission negative regulation of ruffle assembly negative regulation of ruffle assembly regulation of synaptic vesicle exocytosis |
04810 |
| 1426554_a_at |
Pgam1 |
phosphoglycerate mutase 1 |
19 |
41911870 |
BI407347 |
18648 |
60 |
catalytic activity bisphosphoglycerate mutase activity phosphoglycerate mutase activity phosphoglycerate mutase activity cytoplasm cytosol cytosol gluconeogenesis glycolytic process hydrolase activity isomerase activity intramolecular phosphotransferase activity protein kinase binding myelin sheath glyceraldehyde-3-phosphate biosynthetic process 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity sperm principal piece |
00010 01100 |
| 1438640_x_at |
Pgk1 |
phosphoglycerate kinase 1 |
X |
106187099 |
AV305101 |
18655 |
202 |
nucleotide binding phosphoglycerate kinase activity phosphoglycerate kinase activity phosphoglycerate kinase activity protein binding ATP binding ATP binding extracellular space cytoplasm cytosol cytosol gluconeogenesis gluconeogenesis glycolytic process glycolytic process glycolytic process kinase activity phosphorylation negative regulation of angiogenesis transferase activity plasminogen activation ADP binding ADP binding membrane raft glyceraldehyde-3-phosphate biosynthetic process protein-disulfide reductase (NAD(P)) activity canonical glycolysis cellular response to hypoxia |
00010 01100 |
| 1424302_at |
Pirb |
paired Ig-like receptor B |
7 |
-3712504, -3712506 |
U96693 |
18733 |
87 |
amyloid-beta binding amyloid-beta binding B cell homeostasis adaptive immune response immune system process protein binding extracellular space cytoplasm plasma membrane plasma membrane learning or memory protein phosphatase 1 binding external side of plasma membrane cell surface membrane cytokine-mediated signaling pathway cytokine-mediated signaling pathway B cell mediated immunity MHC class Ib protein complex binding MHC class Ib protein binding HLA-A specific inhibitory MHC class I receptor activity HLA-B specific inhibitory MHC class I receptor activity MHC class I receptor activity MHC class Ib receptor activity inhibitory MHC class I receptor activity inhibitory MHC class I receptor activity positive regulation of protein dephosphorylation SH2 domain binding MHC class I protein binding protein homodimerization activity protein homodimerization activity myeloid dendritic cell differentiation protein-containing complex binding protein-containing complex binding negative regulation of osteoclast differentiation cell adhesion molecule binding negative regulation of protein metabolic process regulation of long-term synaptic potentiation positive regulation of long-term synaptic depression |
04380 04662 |
| 1420611_at |
Prkacb |
protein kinase, cAMP dependent, catalytic, beta |
3 |
-146729578, -146729578, -146729578, -146729578 |
AV024339 |
18749 |
72 |
nucleotide binding magnesium ion binding magnesium ion binding neural tube closure protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity AMP-activated protein kinase activity cAMP-dependent protein kinase activity cAMP-dependent protein kinase activity cAMP-dependent protein kinase activity ATP binding ATP binding nucleus nucleus cytoplasm centrosome cytosol cytosol plasma membrane cAMP-dependent protein kinase complex cAMP-dependent protein kinase complex cAMP-dependent protein kinase complex protein phosphorylation protein phosphorylation adenylate cyclase-modulating G protein-coupled receptor signaling pathway protein kinase A signaling membrane kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation ubiquitin protein ligase binding negative regulation of smoothened signaling pathway perinuclear region of cytoplasm negative regulation of meiotic cell cycle regulation of protein processing ciliary base negative regulation of TORC1 signaling |
04010 04020 04062 04114 04210 04270 04310 04340 04540 04720 04740 04742 04910 04912 04914 04916 04962 04970 04971 04976 05020 05146 05414 |
| 1460419_a_at |
Prkcb |
protein kinase C, beta |
7 |
122289124 |
X59274 |
18751 |
236 |
nucleotide binding adaptive immune response immune system process chromatin binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity diacylglycerol-dependent serine/threonine kinase activity diacylglycerol-dependent serine/threonine kinase activity protein kinase C binding calcium channel regulator activity protein binding ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm centrosome cytosol plasma membrane plasma membrane chromatin organization regulation of transcription by RNA polymerase II protein phosphorylation calcium ion transport intracellular calcium ion homeostasis apoptotic process phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway spectrin zinc ion binding response to xenobiotic stimulus regulation of glucose transmembrane transport negative regulation of glucose transmembrane transport regulation of dopamine secretion kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation nuclear receptor coactivator activity positive regulation of vascular endothelial growth factor receptor signaling pathway brush border membrane positive regulation of insulin secretion histone H3T6 kinase activity intracellular signal transduction regulation of growth B cell activation histone binding positive regulation of canonical NF-kappaB signal transduction post-translational protein modification calyx of Held calyx of Held positive regulation of angiogenesis negative regulation of insulin receptor signaling pathway metal ion binding nuclear androgen receptor binding B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway cellular response to carbohydrate stimulus presynapse presynaptic modulation of chemical synaptic transmission presynaptic modulation of chemical synaptic transmission presynaptic cytosol regulation of synaptic vesicle exocytosis regulation of synaptic vesicle exocytosis |
04010 04012 04020 04062 04070 04270 04310 04370 04510 04530 04540 04650 04662 04664 04666 04670 04720 04730 04912 04916 04960 04970 04971 04972 04973 05140 05143 05146 05200 05214 05223 |
| 1450172_at |
Pknox1 |
Pbx/knotted 1 homeobox |
17 |
31564772 |
AA409923 |
18771 |
99 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific angiogenesis angiogenesis DNA binding chromatin binding protein binding nucleus nucleoplasm transcription regulator complex cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II hemopoiesis T cell differentiation erythrocyte differentiation camera-type eye development sequence-specific DNA binding positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding |
|
| 1452521_a_at |
Plaur |
plasminogen activator, urokinase receptor |
7 |
24462482 |
X62701 |
18793 |
202 |
positive regulation of protein phosphorylation signaling receptor binding protein binding extracellular region plasma membrane plasma membrane plasma membrane external side of plasma membrane cell surface regulation of plasminogen activation membrane enzyme binding protein domain specific binding regulation of cell adhesion positive regulation of homotypic cell-cell adhesion urokinase plasminogen activator signaling pathway negative regulation of apoptotic process positive regulation of DNA binding positive regulation of epidermal growth factor receptor signaling pathway mesenchymal cell differentiation regulation of fibrinolysis epithelial cell differentiation involved in prostate gland development positive regulation of release of cytochrome c from mitochondria side of membrane protein complex involved in cell-matrix adhesion serine-type endopeptidase complex serine-type endopeptidase complex negative regulation of intrinsic apoptotic signaling pathway negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
04610 |
| 1435043_at |
Plcb1 |
phospholipase C, beta 1 |
2 |
134786163 |
BB794831 |
18795 |
121 |
G2/M transition of mitotic cell cycle G2/M transition of mitotic cell cycle chromatin oocyte maturation phosphatidylinositol phospholipase C activity phosphatidylinositol phospholipase C activity phosphatidylinositol phospholipase C activity GTPase activator activity calcium ion binding protein binding calmodulin binding calmodulin binding lamin binding phosphatidylinositol-4,5-bisphosphate binding nucleus nucleus cytoplasm cytoplasm cytoplasm plasma membrane plasma membrane mRNA processing lipid metabolic process cell adhesion signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway G protein-coupled acetylcholine receptor signaling pathway glutamate receptor signaling pathway brain development memory memory phosphoric diester hydrolase activity regulation of G protein-coupled receptor signaling pathway insulin receptor signaling pathway membrane lipid catabolic process nuclear speck nuclear speck nuclear speck hydrolase activity enzyme binding cerebral cortex development erythrocyte differentiation macrophage differentiation phosphatidylinositol catabolic process positive regulation of insulin secretion positive regulation of insulin secretion positive regulation of sodium:proton antiporter activity positive regulation of interleukin-12 production inositol trisphosphate metabolic process protein-containing complex response to monosaccharide intracellular signal transduction interleukin-12-mediated signaling pathway interleukin-15-mediated signaling pathway positive regulation of embryonic development identical protein binding myelin sheath response to peptide hormone fat cell differentiation positive regulation of myoblast differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of JNK cascade phosphatidylinositol metabolic process phosphatidylinositol metabolic process insulin-like growth factor receptor signaling pathway phosphatidylinositol-mediated signaling positive regulation of developmental growth release of sequestered calcium ion into cytosol activation of meiosis involved in egg activation interleukin-1-mediated signaling pathway regulation of fertilization glutamatergic synapse glutamatergic synapse glutamatergic synapse GABA-ergic synapse GABA-ergic synapse ion channel modulating, G protein-coupled receptor signaling pathway postsynaptic modulation of chemical synaptic transmission postsynaptic modulation of chemical synaptic transmission postsynaptic modulation of chemical synaptic transmission regulation of retrograde trans-synaptic signaling by endocanabinoid regulation of retrograde trans-synaptic signaling by endocanabinoid postsynaptic cytosol postsynaptic cytosol positive regulation of G1/S transition of mitotic cell cycle cellular response to fluoride regulation of establishment of endothelial barrier cellular response to vasopressin cellular response to ionomycin cellular response to glyceraldehyde ligand-gated ion channel signaling pathway positive regulation of acrosome reaction negative regulation of monocyte extravasation positive regulation of CD24 production |
00562 01100 04020 04062 04070 04270 04310 04540 04720 04730 04912 04916 04970 04971 04972 05010 05016 05142 05143 05146 |
| 1435149_at |
Plcg1 |
phospholipase C, gamma 1 |
2 |
160731309 |
BM121087 |
18803 |
204 |
in utero embryonic development ruffle phosphatidylinositol phospholipase C activity phosphatidylinositol phospholipase C activity phosphatidylinositol phospholipase C activity phospholipase C activity phospholipase C activity guanyl-nucleotide exchange factor activity insulin receptor binding neurotrophin TRKA receptor binding calcium ion binding protein binding cytoplasm cytosol cytosol plasma membrane plasma membrane cell-cell junction lipid metabolic process calcium ion transport signal transduction epidermal growth factor receptor signaling pathway phosphoric diester hydrolase activity COP9 signalosome phospholipid catabolic process response to organonitrogen compound positive regulation of epithelial cell migration positive regulation of epithelial cell migration lipid catabolic process cell migration hydrolase activity calcium-mediated signaling protein kinase binding lamellipodium clathrin-coated vesicle receptor tyrosine kinase binding phosphatidylinositol catabolic process ruffle membrane ruffle membrane inositol trisphosphate metabolic process inositol trisphosphate biosynthetic process glutamate receptor binding intracellular signal transduction cell projection positive regulation of blood vessel endothelial cell migration positive regulation of angiogenesis phosphatidylinositol metabolic process phosphatidylinositol metabolic process metal ion binding phosphatidylinositol-mediated signaling calcium-dependent phospholipase C activity modulation of chemical synaptic transmission modulation of chemical synaptic transmission T cell receptor signaling pathway release of sequestered calcium ion into cytosol phosphoprotein binding positive regulation of release of sequestered calcium ion into cytosol cellular response to epidermal growth factor stimulus Schaffer collateral - CA1 synapse Schaffer collateral - CA1 synapse glutamatergic synapse glutamatergic synapse response to curcumin positive regulation of vascular endothelial cell proliferation positive regulation of endothelial cell apoptotic process |
00562 01100 04012 04020 04070 04370 04650 04660 04664 04666 04670 04722 05200 05214 05223 |
| 1437113_s_at |
Pld1 |
phospholipase D1 |
3 |
27984170, 27938679 |
BM228590 |
18805 |
126 |
catalytic activity phospholipase D activity phospholipase D activity phospholipase D activity protein binding cytoplasm endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus lipid metabolic process phosphatidic acid biosynthetic process phospholipid biosynthetic process phospholipid catabolic process phospholipid catabolic process membrane lipid catabolic process apical plasma membrane hydrolase activity lamellipodium endocytic vesicle positive regulation of cell migration cellular response to nutrient vesicle Golgi cisterna regulation of microvillus assembly regulation of microvillus assembly phosphatidylinositol binding intracellular membrane-bounded organelle response to peptide hormone synapse positive regulation of translation defense response to Gram-positive bacterium regulation of vesicle-mediated transport N-acylphosphatidylethanolamine-specific phospholipase D activity plasma membrane region regulation of synaptic vesicle cycle cholinergic synapse |
00564 00565 01100 04144 04666 04912 05212 |
| 1416289_at |
Plod1 |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
4 |
-147909752 |
NM_011122 |
18822 |
43 |
iron ion binding protein binding endoplasmic reticulum endoplasmic reticulum ferrous iron binding procollagen-lysine 5-dioxygenase activity procollagen-lysine 5-dioxygenase activity epidermis development membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen peptidyl-lysine hydroxylation peptidyl-lysine hydroxylation L-ascorbic acid binding peptide binding metal ion binding dioxygenase activity collagen-containing extracellular matrix catalytic complex |
00310 |
| 1456103_at |
Pml |
promyelocytic leukemia |
9 |
-58217179 |
BB667149 |
18854 |
209 |
chromosome, telomeric region heterochromatin response to hypoxia response to hypoxia positive regulation of defense response to virus by host immune system process DNA binding transcription coactivator activity transcription coactivator activity protein binding nucleus nucleus nucleoplasm nucleoplasm nucleolus cytoplasm endosome endoplasmic reticulum cytosol regulation of DNA-templated transcription protein targeting protein import into nucleus apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest transforming growth factor beta receptor signaling pathway zinc ion binding negative regulation of cell population proliferation negative regulation of cell population proliferation intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to oxidative stress response to UV response to gamma radiation regulation of calcium ion transport into cytosol fibroblast migration membrane nuclear matrix nuclear matrix negative regulation of angiogenesis negative regulation of angiogenesis PML body PML body PML body PML body SUMO transferase activity SUMO transferase activity myeloid cell differentiation regulation of cell adhesion negative regulation of cell growth PML body organization PML body organization protein-containing complex localization ubiquitin protein ligase binding nuclear membrane SUMO binding positive regulation of telomere maintenance negative regulation of telomere maintenance via telomerase endoplasmic reticulum calcium ion homeostasis negative regulation of interleukin-1 beta production negative regulation of interleukin-1 production circadian regulation of gene expression negative regulation of translation in response to oxidative stress response to cytokine regulation of circadian rhythm intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator identical protein binding protein homodimerization activity entrainment of circadian clock by photoperiod proteasome-mediated ubiquitin-dependent protein catabolic process suppression of viral release by host suppression of viral release by host suppression of viral release by host innate immune response innate immune response innate immune response cell fate commitment negative regulation of DNA-templated transcription negative regulation of mitotic cell cycle SMAD binding metal ion binding protein heterodimerization activity positive regulation of fibroblast proliferation retinoic acid receptor signaling pathway rhythmic process protein stabilization cobalt ion binding maintenance of protein location in nucleus defense response to virus regulation of cell cycle negative regulation of telomerase activity positive regulation of apoptotic process involved in mammary gland involution molecular adaptor activity SMAD protein signal transduction branching involved in mammary gland duct morphogenesis ubiquitin-like protein ligase activity protein-containing complex assembly intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress cellular response to interleukin-4 intrinsic apoptotic signaling pathway by p53 class mediator cellular senescence oncogene-induced cell senescence extrinsic apoptotic signaling pathway sumo-dependent protein binding positive regulation of signal transduction by p53 class mediator positive regulation of protein localization to chromosome, telomeric region cellular response to leukemia inhibitory factor negative regulation of ubiquitin-dependent protein catabolic process positive regulation of peptidyl-lysine acetylation regulation of double-strand break repair positive regulation of apoptotic signaling pathway positive regulation of apoptotic signaling pathway positive regulation of extrinsic apoptotic signaling pathway |
04120 04144 05200 05221 |
| 1416530_a_at |
Pnp |
purine-nucleoside phosphorylase |
14 |
50944302 |
BC003788 |
18950 |
89 |
allantoin metabolic process allantoin metabolic process allantoin metabolic process nucleoside binding positive regulation of T cell mediated cytotoxicity purine nucleobase binding catalytic activity purine-nucleoside phosphorylase activity purine-nucleoside phosphorylase activity purine-nucleoside phosphorylase activity purine-nucleoside phosphorylase activity extracellular region cytoplasm cytoplasm cytosol cytosol nucleobase-containing compound metabolic process inosine catabolic process inosine catabolic process inosine catabolic process deoxyinosine catabolic process deoxyinosine catabolic process adenosine catabolic process adenosine catabolic process deoxyadenosine catabolic process deoxyadenosine catabolic process deoxyguanosine catabolic process purine ribonucleoside salvage GTP biosynthetic process AMP catabolic process AMP catabolic process GMP catabolic process to guanine IMP catabolic process IMP catabolic process DNA repair nicotinamide riboside catabolic process immune response intrinsic apoptotic signaling pathway in response to DNA damage apoptotic mitochondrial changes nucleoside metabolic process nucleotide biosynthetic process response to xenobiotic stimulus response to gamma radiation transferase activity glycosyltransferase activity pentosyltransferase activity B cell differentiation GMP salvage IMP salvage positive regulation of interleukin-2 production urate biosynthetic process urate biosynthetic process T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation purine nucleoside metabolic process purine nucleoside metabolic process purine nucleoside metabolic process phosphate ion binding identical protein binding purine-containing compound salvage amide catabolic process amide catabolic process amide catabolic process AMP salvage positive regulation of B cell differentiation positive regulation of DNA repair GMP catabolic process dGMP catabolic process dGMP catabolic process dAMP catabolic process dAMP catabolic process dGTP metabolic process guanosine catabolic process alpha-beta T cell differentiation positive regulation of alpha-beta T cell differentiation positive regulation of alpha-beta T cell differentiation guanosine phosphorylase activity T cell apoptotic process negative regulation of T cell apoptotic process |
00230 00240 00760 01100 |
| 1423272_at |
Polg |
polymerase (DNA directed), gamma |
7 |
-79446230, -79446230 |
BM934958 |
18975 |
128 |
protease binding DNA binding chromatin binding DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity exonuclease activity protein binding mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial matrix gamma DNA polymerase complex DNA replication DNA-templated DNA replication mitochondrial DNA replication mitochondrial DNA replication mitochondrial DNA replication single-stranded DNA 3'-5' DNA exonuclease activity determination of adult lifespan 3'-5' exonuclease activity 3'-5' exonuclease activity transferase activity nucleotidyltransferase activity protein-containing complex mitochondrial nucleoid terminal bouton intracellular membrane-bounded organelle DNA replication proofreading 5'-deoxyribose-5-phosphate lyase activity |
01100 |
| 1418190_at |
Pon1 |
paraoxonase 1 |
6 |
-5168089 |
NM_011134 |
18979 |
101 |
aryldialkylphosphatase activity aryldialkylphosphatase activity arylesterase activity arylesterase activity arylesterase activity calcium ion binding phospholipid binding extracellular region extracellular space extracellular space blood circulation high-density lipoprotein particle binding cholesterol metabolic process cholesterol metabolic process response to toxic substance response to toxic substance positive regulation of cholesterol efflux hydrolase activity aromatic compound catabolic process positive regulation of transporter activity high-density lipoprotein particle spherical high-density lipoprotein particle protein homodimerization activity carboxylic acid catabolic process organophosphate catabolic process phosphatidylcholine metabolic process metal ion binding positive regulation of binding acyl-L-homoserine-lactone lactonohydrolase activity response to fluoride |
01100 |
| 1416957_at |
Pou2af1 |
POU domain, class 2, associating factor 1 |
9 |
51213689 |
NM_011136 |
18985 |
83 |
germinal center B cell differentiation DNA binding transcription coactivator activity transcription coactivator activity transcription coactivator activity protein binding nucleus positive regulation of interleukin-6 production positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II POU domain binding RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex cellular response to virus |
|
| 1449937_at |
Endou |
endonuclease, polyU-specific |
15 |
-97711018, -97711018 |
AI528824 |
19011 |
17 |
RNA binding nuclease activity endonuclease activity RNA endonuclease activity RNA endonuclease activity scavenger receptor activity extracellular region cytoplasm proteolysis immune response post-transcriptional gene silencing hydrolase activity lyase activity polysaccharide binding metal ion binding negative regulation of lipid catabolic process |
|
| 1448380_at |
Lgals3bp |
lectin, galactoside-binding, soluble, 3 binding protein |
11 |
-118392746 |
NM_011150 |
19039 |
41 |
scavenger receptor activity scavenger receptor activity protein binding extracellular region extracellular space extracellular space extracellular space cell adhesion membrane |
|
| 1420743_a_at |
Ppp3cc |
protein phosphatase 3, catalytic subunit, gamma isoform |
14 |
-70222978, -70217864 |
NM_008915 |
19057 |
40 |
phosphoprotein phosphatase activity protein serine/threonine phosphatase activity calcium-dependent protein serine/threonine phosphatase activity calcium-dependent protein serine/threonine phosphatase activity calcium-dependent protein serine/threonine phosphatase activity protein binding calmodulin binding calmodulin binding cytoplasm cytoplasm mitochondrion cytosol calcineurin complex calcineurin complex calcineurin complex calcineurin complex protein dephosphorylation penetration of zona pellucida protein serine/threonine phosphatase complex hydrolase activity myosin phosphatase activity calcineurin-NFAT signaling cascade calmodulin-dependent protein phosphatase activity calmodulin-dependent protein phosphatase activity sperm flagellum metal ion binding positive regulation of calcineurin-NFAT signaling cascade sperm midpiece sperm mitochondrial sheath calcineurin-mediated signaling calcineurin-mediated signaling presynapse glutamatergic synapse glutamatergic synapse presynaptic cytosol regulation of synaptic vesicle endocytosis positive regulation of synaptic vesicle endocytosis positive regulation of calcium ion import across plasma membrane negative regulation of calcium ion import across plasma membrane |
04010 04020 04114 04210 04310 04360 04370 04380 04650 04660 04662 04720 05010 05014 |
| 1421926_at |
Mapk11 |
mitogen-activated protein kinase 11 |
15 |
-89142483 |
AV329330 |
19094 |
82 |
MAPK cascade nucleotide binding osteoblast differentiation protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity MAP kinase activity MAP kinase activity MAP kinase activity protein binding ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol cytosol protein phosphorylation positive regulation of gene expression kinase activity phosphorylation transferase activity stress-activated protein kinase signaling cascade positive regulation of interleukin-12 production intracellular signal transduction p38MAPK cascade stress-activated MAPK cascade stress-activated MAPK cascade cardiac muscle cell proliferation regulation of cardiac muscle cell proliferation negative regulation of cardiac muscle cell proliferation bone development cellular response to interleukin-1 cellular response to UV-B cellular response to virus |
04010 04370 04380 04620 04621 04622 04660 04664 04670 04722 04912 04914 05014 05140 05142 05145 05160 |
| 1440866_at |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
17 |
-78852549 |
AV328340 |
19106 |
234 |
nucleotide binding positive regulation of cytokine production immune system process RNA binding double-stranded RNA binding double-stranded RNA binding protein kinase activity protein kinase activity protein kinase activity protein serine/threonine kinase activity eukaryotic translation initiation factor 2alpha kinase activity eukaryotic translation initiation factor 2alpha kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding nucleus nucleus cytoplasm cytoplasm cytosol translation protein phosphorylation protein phosphorylation response to virus response to toxic substance kinase activity phosphorylation transferase activity negative regulation of translation endoplasmic reticulum unfolded protein response response to lipopolysaccharide positive regulation of chemokine production positive regulation of stress-activated MAPK cascade response to vitamin E negative regulation of osteoblast proliferation cellular response to amino acid starvation response to interferon-alpha eiF2alpha phosphorylation in response to endoplasmic reticulum stress identical protein binding positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of MAPK cascade negative regulation of viral genome replication negative regulation of viral genome replication innate immune response protein autophosphorylation protein autophosphorylation perinuclear region of cytoplasm positive regulation of NF-kappaB transcription factor activity defense response to virus antiviral innate immune response regulation of NLRP3 inflammasome complex assembly positive regulation of non-canonical NF-kappaB signal transduction regulation of hematopoietic progenitor cell differentiation regulation of hematopoietic stem cell proliferation regulation of hematopoietic stem cell differentiation |
04141 05160 |
| 1455696_a_at |
Prpf4b |
pre-mRNA processing factor 4B |
13 |
34875528 |
BB344827 |
19134 |
28 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleus spliceosomal complex chromosome mRNA processing protein phosphorylation protein phosphorylation RNA splicing kinase activity phosphorylation nuclear speck transferase activity mRNA cis splicing, via spliceosome catalytic step 2 spliceosome |
|
| 1419669_at |
Prtn3 |
proteinase 3 |
10 |
79879666 |
U97073 |
19152 |
39 |
serine-type endopeptidase activity serine-type endopeptidase activity signaling receptor binding protein binding extracellular region extracellular space lysosome cytosol plasma membrane proteolysis proteolysis membrane protein ectodomain proteolysis peptidase activity serine-type peptidase activity membrane hydrolase activity enzyme binding collagen catabolic process azurophil granule lumen intracellular membrane-bounded organelle positive regulation of GTPase activity plasma membrane raft cell-cell junction maintenance negative regulation of phagocytosis neutrophil extravasation mature conventional dendritic cell differentiation |
|
| 1417385_at |
Npepps |
aminopeptidase puromycin sensitive |
11 |
-97205841 |
AK010446 |
19155 |
45 |
aminopeptidase activity extracellular space nucleus cytoplasm cytoplasm cytosol proteolysis proteolysis peptidase activity metallopeptidase activity zinc ion binding zinc ion binding membrane hydrolase activity peptide binding peptide catabolic process metal ion binding metalloaminopeptidase activity cellular response to hypoxia |
|
| 1418183_a_at |
Cyth1 |
cytohesin 1 |
11 |
-118164169, -118164169, -118181100, -118164169, -118181100 |
AB013464 |
19157 |
34 |
guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm cytosol plasma membrane plasma membrane bicellular tight junction lipid binding cytoplasmic side of plasma membrane membrane neuromuscular junction regulation of ARF protein signal transduction anchoring junction establishment of epithelial cell polarity extrinsic component of presynaptic membrane presynaptic modulation of chemical synaptic transmission |
|
| 1421410_a_at |
Pstpip2 |
proline-serine-threonine phosphatase-interacting protein 2 |
18 |
77794549 |
BC002123 |
19201 |
43 |
actin binding protein binding cytoplasm cytoplasm cytosol cytoskeleton actin filament plasma membrane cytoskeleton organization membrane actin filament polymerization actin filament binding |
|
| 1428853_at |
Ptch1 |
patched 1 |
13 |
-63508327, -63508327 |
BG071079 |
19206 |
1421 |
negative regulation of transcription by RNA polymerase II branching involved in ureteric bud morphogenesis in utero embryonic development cell fate determination neural tube formation neural tube closure heart morphogenesis patched binding smoothened binding smoothened binding protein binding extracellular region Golgi apparatus plasma membrane plasma membrane plasma membrane plasma membrane caveola cilium signal transduction regulation of mitotic cell cycle pattern specification process brain development hedgehog receptor activity hedgehog receptor activity heparin binding zinc ion binding negative regulation of cell population proliferation epidermis development animal organ morphogenesis dorsal/ventral pattern formation epidermal cell fate specification response to chlorate negative regulation of keratinocyte proliferation positive regulation of cholesterol efflux cholesterol binding cholesterol binding membrane protein processing spinal cord motor neuron differentiation neural tube patterning dorsal/ventral neural tube patterning neural plate axis specification embryonic limb morphogenesis embryonic limb morphogenesis cyclin binding cyclin binding midbody mammary gland development regulation of protein localization regulation of protein localization limb morphogenesis hindlimb morphogenesis regulation of growth negative regulation of multicellular organism growth regulation of cell population proliferation glucose homeostasis intracellular membrane-bounded organelle negative regulation of DNA-binding transcription factor activity keratinocyte proliferation dendritic growth cone axonal growth cone protein-containing complex binding apical part of cell positive regulation of epidermal cell differentiation negative regulation of osteoblast differentiation negative regulation of smoothened signaling pathway negative regulation of smoothened signaling pathway negative regulation of smoothened signaling pathway negative regulation of smoothened signaling pathway negative regulation of smoothened signaling pathway negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription perinuclear region of cytoplasm embryonic organ development epithelial cell proliferation negative regulation of epithelial cell proliferation negative regulation of cell division pharyngeal system development mammary gland duct morphogenesis mammary gland epithelial cell differentiation cell differentiation involved in kidney development somite development somite development cellular response to cholesterol cellular response to cholesterol commissural neuron axon guidance stem cell proliferation cell proliferation involved in metanephros development protein localization to plasma membrane hedgehog family protein binding hedgehog family protein binding negative regulation of stem cell proliferation |
04340 05200 05217 |
| 1416249_at |
Nadk |
NAD kinase |
4 |
155563814, 155562380 |
AW538068 |
192185 |
26 |
nucleotide binding NAD+ kinase activity NAD+ kinase activity NAD+ kinase activity ATP binding cytosol NADP biosynthetic process NADP biosynthetic process kinase activity phosphorylation transferase activity NAD metabolic process positive regulation of insulin secretion involved in cellular response to glucose stimulus metal ion binding |
00760 01100 |
| 1450071_at |
Ash1l |
ASH1 like histone lysine methyltransferase |
3 |
88965811 |
BG694892 |
192195 |
45 |
MAPK cascade skeletal system development negative regulation of acute inflammatory response DNA binding chromatin binding nucleus nucleoplasm nucleoplasm chromosome Golgi apparatus bicellular tight junction chromatin organization regulation of DNA-templated transcription transcription by RNA polymerase II inflammatory response single fertilization methyltransferase activity post-embryonic development regulation of gene expression macrophage cytokine production transferase activity flagellated sperm motility methylation interleukin-6 production histone methyltransferase activity histone H3K4 methyltransferase activity histone H3K4 methyltransferase activity histone H3K4 methyltransferase activity negative regulation of MAPK cascade positive regulation of transcription by RNA polymerase II decidualization metal ion binding histone H3K9 methyltransferase activity histone H3K36 methyltransferase activity sebaceous gland development negative regulation of inflammatory response uterus morphogenesis anchoring junction histone H3K9 monomethyltransferase activity histone H3K36 trimethyltransferase activity tarsal gland development uterine gland development |
00310 04530 |
| 1436766_at |
Luc7l2 |
LUC7-like 2 (S. cerevisiae) |
6 |
38555722, 38551333, 38551333 |
BB475271 |
192196 |
30 |
mRNA binding mRNA binding nucleus U1 snRNP U1 snRNP mRNA splice site recognition mRNA splice site recognition nuclear speck enzyme binding U2-type prespliceosome |
|
| 1436448_a_at |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
2 |
36230425 |
AA833146 |
19224 |
318 |
prostaglandin biosynthetic process prostaglandin biosynthetic process photoreceptor outer segment peroxidase activity prostaglandin-endoperoxide synthase activity prostaglandin-endoperoxide synthase activity nuclear envelope cytoplasm cytoplasm cytoplasm endoplasmic reticulum Golgi apparatus lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process prostaglandin metabolic process response to oxidative stress learning memory regulation of blood pressure negative regulation of norepinephrine secretion membrane oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen cyclooxygenase pathway cyclooxygenase pathway heme binding keratinocyte differentiation negative regulation of epinephrine secretion maintenance of blood-brain barrier regulation of cell population proliferation neuron projection intracellular membrane-bounded organelle positive regulation of vasoconstriction positive regulation of smooth muscle contraction metal ion binding dioxygenase activity |
00590 01100 |
| 1419657_a_at |
Slc25a36 |
solute carrier family 25, member 36 |
9 |
-97077010 |
BB503267 |
192287 |
23 |
mitochondrial genome maintenance mitochondrial genome maintenance mitochondrion mitochondrion mitochondrion mitochondrial inner membrane pyrimidine nucleotide transport mitochondrion organization pyrimidine nucleotide transmembrane transporter activity pyrimidine nucleotide transmembrane transporter activity membrane regulation of mitochondrial membrane potential transmembrane transport pyrimidine nucleotide import into mitochondrion |
|
| 1417219_s_at |
Tmsb10 |
thymosin beta 10 |
6 |
-72957346, -72957346, -72957346 |
NM_025284 |
19240 |
36 |
actin monomer binding actin monomer binding cytoplasm cytoplasm actin cytoskeleton organization regulation of cell migration sequestering of actin monomers |
|
| 1448830_at |
Dusp1 |
dual specificity phosphatase 1 |
17 |
-26505590 |
NM_013642 |
19252 |
233 |
endoderm formation phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity nucleus nucleus cytoplasm cytoplasm protein dephosphorylation cell cycle negative regulation of cell adhesion protein tyrosine/serine/threonine phosphatase activity negative regulation of cell population proliferation protein tyrosine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity dephosphorylation hydrolase activity phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity myosin phosphatase activity growth factor binding MAP kinase tyrosine phosphatase activity peptidyl-tyrosine dephosphorylation peptidyl-tyrosine dephosphorylation peptidyl-tyrosine dephosphorylation intracellular signal transduction peptidyl-threonine dephosphorylation positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of MAP kinase activity negative regulation of MAPK cascade mitogen-activated protein kinase binding mitogen-activated protein kinase binding peptidyl-serine dephosphorylation negative regulation of ERK1 and ERK2 cascade negative regulation of monocyte chemotaxis negative regulation of p38MAPK cascade negative regulation of p38MAPK cascade cellular response to chemokine negative regulation of DNA biosynthetic process |
04010 |
| 1448511_at |
Ptprcap |
protein tyrosine phosphatase receptor type C polypeptide-associated protein |
19 |
4154645 |
NM_016933 |
19265 |
30 |
plasma membrane plasma membrane membrane |
|
| 1418539_a_at |
Ptpre |
protein tyrosine phosphatase receptor type E |
7 |
135651898, 135593480, 135537823, 135605827 |
U35368 |
19267 |
54 |
phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity nucleus cytoplasm cytoplasm plasma membrane plasma membrane protein dephosphorylation protein dephosphorylation transmembrane receptor protein tyrosine phosphatase signaling pathway membrane dephosphorylation hydrolase activity phosphatase activity regulation of mast cell activation identical protein binding negative regulation of insulin receptor signaling pathway negative regulation of insulin receptor signaling pathway |
|
| 1438828_at |
Rapgef6 |
Rap guanine nucleotide exchange factor (GEF) 6 |
11 |
54596145, 54596145, 54522844 |
BM243959 |
192786 |
25 |
guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity centrosome cytosol plasma membrane plasma membrane Ras protein signal transduction apical plasma membrane apical plasma membrane microvillus assembly endocytic vesicle endocytic vesicle GTP-dependent protein binding small GTPase binding positive regulation of GTPase activity positive regulation of GTPase activity phosphatidic acid binding protein localization to plasma membrane |
|
| 1416082_at |
Rab1a |
RAB1A, member RAS oncogene family |
11 |
20201411 |
AW108405 |
19324 |
92 |
autophagosome assembly autophagosome assembly Golgi membrane nucleotide binding GTPase activity GTPase activity G protein activity protein binding GTP binding cytoplasm endosome early endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus intracellular protein transport intracellular protein transport endoplasmic reticulum to Golgi vesicle-mediated transport endocytosis autophagy Golgi organization endomembrane system protein transport membrane vesicle-mediated transport cell migration cell migration hydrolase activity virion assembly growth hormone secretion melanosome transport positive regulation of interleukin-8 production substrate adhesion-dependent cell spreading melanosome defense response to bacterium neuronal cell body synapse vesicle transport along microtubule COPII-coated vesicle cargo loading presynapse positive regulation of glycoprotein metabolic process |
|
| 1438097_at |
Rab20 |
RAB20, member RAS oncogene family |
8 |
-11453389 |
BG066967 |
19332 |
33 |
nucleotide binding GTPase activity GTPase activity GTP binding Golgi apparatus intracellular protein transport endomembrane system protein transport membrane cytoplasmic vesicle intracellular membrane-bounded organelle phagocytic vesicle phagocytic vesicle cellular response to type II interferon phagosome acidification phagosome-lysosome fusion |
|
| 1418890_a_at |
Rab3d |
RAB3D, member RAS oncogene family |
9 |
-21907491 |
BB349707 |
19340 |
61 |
nucleotide binding GTPase activity GTPase activity protein binding GTP binding mitochondrion endosome cytoplasmic microtubule plasma membrane plasma membrane exocytosis vesicle docking involved in exocytosis synaptic vesicle protein secretion protein transport membrane regulation of exocytosis regulation of exocytosis peptidyl-cysteine methylation GTP-dependent protein binding myosin V binding myosin V binding zymogen granule bone resorption protein localization to plasma membrane secretory vesicle positive regulation of regulated secretory pathway |
04972 |
| 1440208_at |
Rac2 |
Rac family small GTPase 2 |
15 |
-78559168 |
BE691393 |
19354 |
153 |
nucleotide binding GTPase activity GTPase activity protein binding GTP binding GTP binding nuclear envelope cytoplasm cytosol actin filament plasma membrane chemotaxis chemotaxis actin filament organization actin filament organization signal transduction G protein-coupled receptor signaling pathway small GTPase-mediated signal transduction cell population proliferation cell population proliferation positive regulation of lamellipodium assembly positive regulation of lamellipodium assembly positive regulation of lamellipodium assembly regulation of cell-substrate adhesion membrane protein kinase regulator activity lamellipodium cell projection assembly actin cytoskeleton organization actin cytoskeleton organization regulation of cell migration regulation of T cell proliferation erythrocyte enucleation regulation of mast cell degranulation bone resorption regulation of respiratory burst regulation of mast cell chemotaxis mast cell proliferation mast cell proliferation positive regulation of mast cell proliferation positive regulation of mast cell proliferation lymphocyte aggregation positive regulation of neutrophil chemotaxis positive regulation of neutrophil chemotaxis regulation of neutrophil migration |
04010 04062 04310 04360 04370 04510 04520 04650 04662 04664 04666 04670 04810 05200 05210 05212 05416 |
| 1434295_at |
Rasgrp1 |
RAS guanyl releasing protein 1 |
2 |
-117279983 |
BE691356 |
19419 |
85 |
positive regulation of protein phosphorylation inflammatory response to antigenic stimulus guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity calcium ion binding cytoplasm endoplasmic reticulum Golgi apparatus cytosol cytosol plasma membrane plasma membrane plasma membrane small GTPase-mediated signal transduction Ras protein signal transduction zinc ion binding membrane diacylglycerol binding natural killer cell activation cell differentiation phosphatidylcholine binding secretory granule localization positive regulation of granulocyte macrophage colony-stimulating factor production positive regulation of type II interferon production positive regulation of tumor necrosis factor production mast cell cytokine production positive regulation of natural killer cell activation positive regulation of natural killer cell differentiation positive regulation of T cell differentiation in thymus T cell proliferation B cell proliferation T cell activation B cell activation identical protein binding mast cell degranulation positive regulation of MAP kinase activity positive regulation of GTPase activity positive regulation of GTPase activity positive regulation of natural killer cell mediated cytotoxicity positive regulation of JNK cascade positive regulation of Ras protein signal transduction metal ion binding vesicle transport along microtubule regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade activation of GTPase activity activation of GTPase activity |
04010 04660 |
| 1426863_at |
Rbmx |
RNA binding motif protein, X chromosome |
X |
-57383347, -57386029 |
BM123721 |
19655 |
36 |
regulation of alternative mRNA splicing, via spliceosome euchromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding nucleic acid binding chromatin binding RNA binding RNA binding single-stranded RNA binding mRNA binding nucleus spliceosomal complex spliceosomal complex transcription by RNA polymerase II mRNA splice site recognition mRNA processing membrane protein ectodomain proteolysis RNA splicing postsynaptic density protein domain specific binding protein-containing complex identical protein binding supraspliceosomal complex positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of mRNA splicing, via spliceosome extracellular exosome catalytic step 2 spliceosome cellular response to interleukin-1 glutamatergic synapse regulation of postsynapse organization ribonucleoprotein complex |
03040 |
| 1436196_at |
Rel |
reticuloendotheliosis oncogene |
11 |
-23736849 |
BE691546 |
19696 |
259 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific cytokine production DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus cytoplasm cytoplasm regulation of DNA-templated transcription inflammatory response canonical NF-kappaB signal transduction negative regulation of gene expression negative regulation of interferon-beta production positive regulation of interleukin-12 production cellular response to stress response to cytokine non-canonical NF-kappaB signal transduction sequence-specific DNA binding innate immune response positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II |
|
| 1424632_a_at |
Rev3l |
REV3 like, DNA directed polymerase zeta catalytic subunit |
10 |
39732159 |
AB031049 |
19714 |
59 |
nucleotide binding double-strand break repair via homologous recombination nucleic acid binding DNA binding DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity nucleus nucleus nucleolus DNA replication DNA repair DNA damage response zeta DNA polymerase complex zeta DNA polymerase complex transferase activity nucleotidyltransferase activity translesion synthesis error-prone translesion synthesis error-prone translesion synthesis metal ion binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding |
01100 |
| 1448101_s_at |
Trim27 |
tripartite motif-containing 27 |
13 |
21179930 |
NM_009054 |
19720 |
59 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II fibrillar center negative regulation of adaptive immune response DNA binding transcription coactivator activity ubiquitin-protein transferase activity protein binding nucleus nucleoplasm nucleolus cytoplasm cytoplasm cytoplasm mitochondrion endosome negative regulation of protein kinase activity zinc ion binding negative regulation of autophagy transferase activity SUMO transferase activity retromer complex nuclear membrane negative regulation of type I interferon production negative regulation of interleukin-2 production negative regulation of tumor necrosis factor production positive regulation of type II interferon production negative regulation of viral transcription negative regulation of viral transcription negative regulation of viral transcription Arp2/3 complex-mediated actin nucleation retrograde transport, endosome to Golgi identical protein binding suppression of viral release by host innate immune response innate immune response innate immune response negative regulation of gene expression, epigenetic metal ion binding positive regulation of DNA-binding transcription factor activity positive regulation of actin nucleation ubiquitin protein ligase activity ubiquitin protein ligase activity protein K63-linked ubiquitination protein K63-linked ubiquitination negative regulation of calcium ion import |
|
| 1437375_at |
Rfx3 |
regulatory factor X, 3 (influences HLA class II expression) |
19 |
-27761720, -27761720 |
BB745175 |
19726 |
61 |
chromatin chromatin transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus transcription regulator complex DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II multicellular organism development determination of left/right symmetry cell differentiation endocrine pancreas development sequence-specific DNA binding negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II cell maturation regulation of insulin secretion cilium assembly cilium-dependent cell motility epithelial cilium movement involved in determination of left/right asymmetry type B pancreatic cell maturation sequence-specific double-stranded DNA binding positive regulation of type B pancreatic cell development |
|
| 1448948_at |
Slc50a1 |
solute carrier family 50 (sugar transporter), member 1 |
3 |
-89268245 |
NM_009057 |
19729 |
20 |
Golgi apparatus plasma membrane carbohydrate transport carbohydrate transport endomembrane system membrane glucoside transmembrane transporter activity sugar transmembrane transporter activity sugar transmembrane transporter activity |
|
| 1450688_at |
Rgl2 |
ral guanine nucleotide dissociation stimulator-like 2 |
17 |
33929893 |
NM_009059 |
19732 |
24 |
guanyl-nucleotide exchange factor activity signal transduction small GTPase-mediated signal transduction negative regulation of cardiac muscle cell apoptotic process regulation of Ral protein signal transduction positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
|
| 1448852_at |
Rgn |
regucalcin |
X |
20549817 |
NM_009060 |
19733 |
83 |
negative regulation of protein phosphorylation gluconolactonase activity gluconolactonase activity gluconolactonase activity gluconolactonase activity calcium ion binding calcium ion binding nucleus cytoplasm intracellular calcium ion homeostasis spermatogenesis zinc ion binding positive regulation of triglyceride biosynthetic process positive regulation of glucose metabolic process hydrolase activity L-ascorbic acid biosynthetic process L-ascorbic acid biosynthetic process L-ascorbic acid biosynthetic process enzyme regulator activity negative regulation of apoptotic process negative regulation of nitric oxide biosynthetic process positive regulation of fatty acid biosynthetic process metal ion binding negative regulation of epithelial cell proliferation regulation of calcium-mediated signaling negative regulation of flagellated sperm motility negative regulation of RNA biosynthetic process negative regulation of bone development positive regulation of proteolysis involved in protein catabolic process negative regulation of DNA catabolic process negative regulation of DNA biosynthetic process |
|
| 1419273_at |
Uri1 |
URI1, prefoldin-like chaperone |
7 |
-37959991 |
AV278756 |
19777 |
36 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II complex binding regulation of cell growth chromatin binding chromatin binding transcription corepressor activity transcription corepressor activity protein phosphatase inhibitor activity nucleus nucleoplasm cytoplasm mitochondrion cytosol regulation of transcription by RNA polymerase II response to virus negative regulation of phosphatase activity negative regulation of phosphatase activity phosphatase inhibitor activity cell projection phosphoprotein binding cellular response to growth factor stimulus cellular response to steroid hormone stimulus RPAP3/R2TP/prefoldin-like complex negative regulation of intrinsic apoptotic signaling pathway |
|
| 1419311_at |
Trim10 |
tripartite motif-containing 10 |
17 |
36869573 |
NM_011280 |
19824 |
20 |
protein binding cytoplasm cytoplasm zinc ion binding protein ubiquitination erythrocyte differentiation innate immune response innate immune response negative regulation of viral entry into host cell metal ion binding ubiquitin protein ligase activity |
|
| 1419586_at |
Rp2 |
retinitis pigmentosa 2 homolog |
X |
20364480, 20364480 |
BF168611 |
19889 |
27 |
nucleotide binding magnesium ion binding GTPase activator activity GTPase activator activity GTP binding nucleoplasm cytoplasm Golgi apparatus centriole plasma membrane plasma membrane cilium cilium post-Golgi vesicle-mediated transport post-Golgi vesicle-mediated transport protein transport membrane nuclear body cytoplasmic vesicle ciliary basal body ciliary basal body cell projection periciliary membrane compartment periciliary membrane compartment |
|
| 1436699_x_at |
Rpl18 |
ribosomal protein L18 |
7 |
45718070 |
BB422726 |
19899 |
42 |
cytoplasmic translation cytoplasmic translation RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome nucleolus cytoplasm endoplasmic reticulum cytosol cytosol ribosome translation cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome synapse ribonucleoprotein complex |
03010 |
| 1448398_s_at |
Rpl22 |
ribosomal protein L22 |
4 |
152324435, 152325725 |
NM_009079 |
19934 |
248 |
cytoplasmic translation RNA binding RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome nucleus cytoplasm cytosol ribosome ribosome ribosome ribosome ribosome translation heparin binding cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome identical protein binding synapse synapse alpha-beta T cell differentiation presynapse presynapse postsynapse glutamatergic synapse glutamatergic synapse glutamatergic synapse translation at presynapse translation at presynapse translation at presynapse translation at postsynapse ribonucleoprotein complex |
03010 |
| 1455195_at |
Rps24 |
ribosomal protein S24 |
14 |
24490752, 24490677 |
BM119287 |
20088 |
39 |
cytoplasmic translation structural constituent of ribosome structural constituent of ribosome nucleus cytoplasm endoplasmic reticulum cytosol cytosol ribosome rRNA processing translation small ribosomal subunit cytosolic ribosome cytosolic small ribosomal subunit cytosolic small ribosomal subunit cytosolic small ribosomal subunit translation initiation factor binding small-subunit processome erythrocyte homeostasis ribosomal small subunit biogenesis synapse synapse synapse presynapse postsynapse translation at presynapse translation at postsynapse ribonucleoprotein complex |
03010 |
| 1417542_at |
Rps6ka2 |
ribosomal protein S6 kinase, polypeptide 2 |
17 |
7170114 |
BB737182 |
20112 |
61 |
nucleotide binding magnesium ion binding oocyte maturation brain renin-angiotensin system protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ribosomal protein S6 kinase activity ribosomal protein S6 kinase activity protein serine/threonine/tyrosine kinase activity protein binding ATP binding nucleus nucleoplasm nucleoplasm nucleoplasm cytoplasm cytoplasm cytoplasm spindle protein phosphorylation heart development negative regulation of cell population proliferation positive regulation of gene expression cardiac muscle cell apoptotic process kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation intracellular signal transduction positive regulation of apoptotic process negative regulation of cell cycle negative regulation of meiotic nuclear division heart contraction regulation of protein processing cellular response to carbohydrate stimulus meiotic spindle |
04010 04114 04150 04720 04722 04914 |
| 1451860_a_at |
Trim30a |
tripartite motif-containing 30A |
7 |
-104409025, -104409025 |
AF220015 |
20128 |
39 |
protein polyubiquitination P-body activation of innate immune response DNA binding transcription coactivator activity ubiquitin-protein transferase activity nucleus nucleoplasm cytoplasm cytoplasm cytoplasm cytosol autophagy zinc ion binding response to bacterium positive regulation of autophagy protein kinase binding protein kinase binding protein-macromolecule adaptor activity regulation of lipopolysaccharide-mediated signaling pathway negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production regulation of protein localization regulation of protein localization negative regulation of toll-like receptor signaling pathway pattern recognition receptor activity identical protein binding protein homodimerization activity protein homodimerization activity positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of MAPK cascade suppression of viral release by host innate immune response innate immune response positive regulation of protein catabolic process regulation of viral entry into host cell negative regulation of viral entry into host cell positive regulation of viral entry into host cell metal ion binding positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity protein autoubiquitination ubiquitin protein ligase activity protein K63-linked ubiquitination negative regulation of NLRP3 inflammasome complex assembly omegasome negative regulation of reactive oxygen species metabolic process |
|
| 1434437_x_at |
Rrm2 |
ribonucleotide reductase M2 |
12 |
24708253 |
AV301324 |
20135 |
81 |
blastocyst development ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor protein binding nucleus nuclear envelope cytoplasm cytosol cytosol ribonucleoside-diphosphate reductase complex ribonucleoside-diphosphate reductase complex ribonucleoside-diphosphate reductase complex ferric iron binding ribonucleoside diphosphate metabolic process ribonucleoside diphosphate metabolic process deoxyribonucleotide metabolic process deoxyribonucleotide biosynthetic process deoxyribonucleotide biosynthetic process 2'-deoxyribonucleotide biosynthetic process 2'-deoxyribonucleotide biosynthetic process oxidoreductase activity identical protein binding protein homodimerization activity metal ion binding protein heterotetramerization positive regulation of G1/S transition of mitotic cell cycle |
00230 00240 00480 01100 04115 |
| 1460351_at |
S100a11 |
S100 calcium binding protein A11 |
3 |
93520495 |
BC021916 |
20195 |
43 |
ruffle calcium ion binding calcium ion binding extracellular space nucleus cytoplasm cytoplasm cytoplasm positive regulation of smooth muscle cell migration regulation of cell population proliferation protein homodimerization activity S100 protein binding S100 protein binding metal ion binding calcium-dependent protein binding calcium-dependent protein binding collagen-containing extracellular matrix |
|
| 1421375_a_at |
S100a6 |
S100 calcium binding protein A6 (calcyclin) |
3 |
90612893 |
NM_011313 |
20200 |
93 |
ruffle calcium ion binding calcium ion binding calcium ion binding protein binding tropomyosin binding nucleus nucleus nuclear envelope cytoplasm cytosol plasma membrane zinc ion binding cytoplasmic side of plasma membrane monoatomic ion transmembrane transporter activity membrane protein homodimerization activity S100 protein binding S100 protein binding metal ion binding calcium-dependent protein binding calcium-dependent protein binding perinuclear region of cytoplasm perinuclear region of cytoplasm collagen-containing extracellular matrix |
|
| 1419394_s_at |
S100a8 |
S100 calcium binding protein A8 (calgranulin A) |
3 |
90669070 |
NM_013650 |
20201 |
177 |
immune system process leukocyte migration involved in inflammatory response leukocyte migration involved in inflammatory response peptide secretion peptide secretion positive regulation of peptide secretion positive regulation of peptide secretion calcium ion binding calcium ion binding extracellular region extracellular space cytoplasm cytosol cytoskeleton plasma membrane autophagy apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process chemotaxis inflammatory response astrocyte development membrane antioxidant activity peptidyl-cysteine S-nitrosylation neutrophil chemotaxis neutrophil chemotaxis response to lipopolysaccharide regulation of toll-like receptor signaling pathway autocrine signaling innate immune response intermediate filament cytoskeleton metal ion binding calcium-dependent protein binding positive regulation of inflammatory response neutrophil aggregation neutrophil aggregation calprotectin complex positive regulation of intrinsic apoptotic signaling pathway |
|
| 1448756_at |
S100a9 |
S100 calcium binding protein A9 (calgranulin B) |
3 |
-90692629 |
NM_009114 |
20202 |
253 |
cornified envelope immune system process leukocyte migration involved in inflammatory response leukocyte migration involved in inflammatory response chronic inflammatory response peptide secretion peptide secretion positive regulation of peptide secretion positive regulation of peptide secretion calcium ion binding calcium ion binding extracellular region extracellular space cytoplasm cytoplasm cytoskeleton plasma membrane regulation of translation autophagy apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process chemotaxis inflammatory response positive regulation of neuron projection development astrocyte development astrocyte development membrane antioxidant activity peptidyl-cysteine S-nitrosylation peptidyl-cysteine S-nitrosylation actin cytoskeleton organization positive regulation of blood coagulation neutrophil chemotaxis neutrophil chemotaxis leukocyte chemotaxis response to lipopolysaccharide regulation of toll-like receptor signaling pathway autocrine signaling autocrine signaling peptidyl-cysteine S-trans-nitrosylation modulation of process of another organism endothelial cell migration innate immune response regulation of integrin biosynthetic process regulation of integrin biosynthetic process metal ion binding calcium-dependent protein binding positive regulation of inflammatory response regulation of respiratory burst involved in inflammatory response antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide neutrophil aggregation neutrophil aggregation calprotectin complex S100A9 complex positive regulation of intrinsic apoptotic signaling pathway |
|
| 1450788_at |
Saa1 |
serum amyloid A 1 |
7 |
-46740496 |
NM_009117 |
20208 |
104 |
G protein-coupled receptor binding protein binding extracellular region extracellular space cytoplasmic microtubule acute-phase response heparin binding cholesterol metabolic process response to bacterium high-density lipoprotein particle |
|
| 1450826_a_at |
Saa3 |
serum amyloid A 3 |
7 |
-46711997 |
NM_011315 |
20210 |
86 |
extracellular region extracellular space acute-phase response I-kappaB phosphorylation response to bacterium high-density lipoprotein particle response to stilbenoid Toll-like receptor 4 binding chemoattractant activity cell chemotaxis cellular response to interleukin-1 |
|
| 1437389_x_at |
Khdrbs1 |
KH domain containing, RNA binding, signal transduction associated 1 |
4 |
-129703168, -129713814 |
AV117555 |
20218 |
112 |
negative regulation of transcription by RNA polymerase II regulation of alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome nucleic acid binding RNA binding RNA binding mRNA binding protein binding nucleus nucleus nucleus nucleoplasm cytoplasm mRNA processing cell cycle cell surface receptor signaling pathway cell surface receptor signaling pathway poly(A) binding poly(A) binding poly(U) RNA binding membrane SH3 domain binding protein domain specific binding protein-containing complex signaling adaptor activity signaling adaptor activity SH2 domain binding identical protein binding identical protein binding protein-containing complex binding positive regulation of translational initiation regulation of RNA export from nucleus positive regulation of RNA export from nucleus regulation of mRNA splicing, via spliceosome T cell receptor signaling pathway Grb2-Sos complex protein tyrosine kinase binding protein tyrosine kinase binding |
|
| 1419059_at |
Apcs |
amyloid P component, serum |
1 |
-172893960 |
NM_011318 |
20219 |
82 |
complement component C1q complex binding complement component C1q complex binding calcium ion binding extracellular region extracellular space extracellular space carbohydrate binding protein-containing complex identical protein binding negative regulation by host of viral exo-alpha-sialidase activity negative regulation by host of viral glycoprotein metabolic process innate immune response innate immune response negative regulation of monocyte differentiation negative regulation of viral entry into host cell virion binding metal ion binding negative regulation of viral process protein-containing complex assembly negative regulation of exo-alpha-sialidase activity negative regulation of glycoprotein metabolic process |
|
| 1416008_at |
Satb1 |
special AT-rich sequence binding protein 1 |
17 |
-51736186, -51736186, -51736186, -51736186, -51736186 |
AV172776 |
20230 |
111 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin heterochromatin RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding chromatin binding DNA-binding transcription factor activity nucleus nucleoplasm chromatin organization chromatin remodeling chromatin remodeling regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II epidermis development nuclear matrix nuclear body PML body T cell activation CD4-positive, alpha-beta T cell differentiation CD8-positive, alpha-beta T cell differentiation sequence-specific DNA binding activated T cell proliferation reflex DNA-binding transcription factor binding |
|
| 1415964_at |
Scd1 |
stearoyl-Coenzyme A desaturase 1 |
19 |
-44394449 |
NM_009127 |
20249 |
287 |
stearoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity iron ion binding iron ion binding nucleolus endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process unsaturated fatty acid biosynthetic process unsaturated fatty acid biosynthetic process triglyceride metabolic process lipid biosynthetic process response to bacterium membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water palmitoyl-CoA 9-desaturase activity palmitoyl-CoA 9-desaturase activity palmitoyl-CoA 9-desaturase activity cholesterol homeostasis intracellular membrane-bounded organelle metal ion binding sebaceous gland development defense response to Gram-positive bacterium white fat cell differentiation brown fat cell differentiation lipid homeostasis sterol homeostasis response to fatty acid response to fatty acid positive regulation of cold-induced thermogenesis tarsal gland development monounsaturated fatty acid biosynthetic process monounsaturated fatty acid biosynthetic process monounsaturated fatty acid biosynthetic process monounsaturated fatty acid biosynthetic process |
01040 03320 |
| 1415822_at |
Scd2 |
stearoyl-Coenzyme A desaturase 2 |
19 |
44293675 |
BG060909 |
20250 |
57 |
stearoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity iron ion binding iron ion binding nucleolus endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process unsaturated fatty acid biosynthetic process unsaturated fatty acid biosynthetic process membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water palmitoyl-CoA 9-desaturase activity palmitoyl-CoA 9-desaturase activity palmitoyl-CoA 9-desaturase activity intracellular membrane-bounded organelle metal ion binding response to fatty acid response to fatty acid monounsaturated fatty acid biosynthetic process monounsaturated fatty acid biosynthetic process |
01040 03320 |
| 1420764_at |
Scrg1 |
scrapie responsive gene 1 |
8 |
57455922 |
NM_009136 |
20284 |
23 |
extracellular region cytoplasm Golgi apparatus Golgi apparatus neuron projection terminus neuron projection terminus |
|
| 1448061_at |
Msr1 |
macrophage scavenger receptor 1 |
8 |
-39581699, -39603451 |
AA183642 |
20288 |
264 |
amyloid-beta binding amyloid-beta binding scavenger receptor activity collagen trimer plasma membrane plasma membrane endocytosis receptor-mediated endocytosis phagocytosis, engulfment negative regulation of gene expression positive regulation of macrophage derived foam cell differentiation positive regulation of cholesterol storage positive regulation of cholesterol storage membrane low-density lipoprotein particle binding low-density lipoprotein particle binding cholesterol transport low-density lipoprotein particle plasma lipoprotein particle clearance plasma lipoprotein particle clearance cargo receptor activity lipoprotein transport establishment of localization in cell amyloid-beta clearance amyloid-beta clearance amyloid-beta clearance |
04145 |
| 1449984_at |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
5 |
90903898 |
NM_009140 |
20310 |
178 |
response to molecule of bacterial origin cytokine activity extracellular region extracellular space extracellular space extracellular space chemotaxis defense response inflammatory response inflammatory response immune response positive regulation of cytosolic calcium ion concentration chemokine activity chemokine activity neutrophil chemotaxis neutrophil chemotaxis leukocyte chemotaxis CXCR chemokine receptor binding antimicrobial humoral immune response mediated by antimicrobial peptide chemokine-mediated signaling pathway cellular response to lipopolysaccharide |
04060 04062 04621 |
| 1440173_x_at |
Selp |
selectin, platelet |
1 |
164115263 |
BB224329 |
20344 |
395 |
lipopolysaccharide binding positive regulation of leukocyte migration positive regulation of leukocyte migration regulation of cellular extravasation calcium ion binding protein binding extracellular space extracellular space plasma membrane inflammatory response cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte cell-cell adhesion leukocyte cell-cell adhesion heparin binding external side of plasma membrane external side of plasma membrane external side of plasma membrane positive regulation of platelet activation membrane calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules carbohydrate binding platelet alpha granule membrane regulation of integrin activation sialic acid binding sialic acid binding sialic acid binding response to cytokine calcium-mediated signaling using intracellular calcium source fucose binding positive regulation of cell adhesion metal ion binding calcium-dependent protein binding leukocyte migration leukocyte migration leukocyte migration leukocyte tethering or rolling leukocyte tethering or rolling leukocyte tethering or rolling positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction oligosaccharide binding oligosaccharide binding cellular response to interleukin-6 cell-cell adhesion positive regulation of leukocyte tethering or rolling |
04514 05144 05150 |
| 1439768_x_at |
Sema4f |
sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain |
6 |
-82911884 |
BB271145 |
20355 |
33 |
neural crest cell migration protein binding endoplasmic reticulum plasma membrane plasma membrane multicellular organism development nervous system development axon guidance axon guidance membrane cell differentiation semaphorin receptor binding semaphorin receptor binding positive regulation of cell migration negative regulation of axon extension retinal ganglion cell axon guidance cell projection synapse postsynaptic membrane chemorepellent activity axon extension negative regulation of axon extension involved in axon guidance negative chemotaxis semaphorin-plexin signaling pathway postsynaptic density membrane glutamatergic synapse |
04360 |
| 1418747_at |
Spi1 |
Spi-1 proto-oncogene |
2 |
91096677, 91096699, 91082404 |
NM_011355 |
20375 |
445 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin chromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding cis-regulatory region sequence-specific DNA binding cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific vasculature development germinal center B cell differentiation follicular B cell differentiation lymphoid progenitor cell differentiation immature B cell differentiation defense response to tumor cell pro-T cell differentiation myeloid leukocyte differentiation myeloid leukocyte differentiation DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity RNA binding protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex transcription regulator complex regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transforming growth factor beta receptor signaling pathway multicellular organism development positive regulation of gene expression negative regulation of gene expression negative regulation of gene expression lymphocyte differentiation cell differentiation erythrocyte differentiation macrophage differentiation granulocyte differentiation lipopolysaccharide-mediated signaling pathway negative regulation of NF-kappaB transcription factor activity somatic stem cell population maintenance TRAIL-activated apoptotic signaling pathway histone deacetylase binding myeloid dendritic cell differentiation negative regulation of neutrophil degranulation sequence-specific DNA binding sequence-specific DNA binding negative regulation of MHC class II biosynthetic process positive regulation of B cell differentiation regulation of erythrocyte differentiation transcription initiation-coupled chromatin remodeling transcription initiation-coupled chromatin remodeling negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of DNA-binding transcription factor activity NFAT protein binding anatomical structure regression molecular adaptor activity RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II-specific DNA-binding transcription factor binding interleukin-6-mediated signaling pathway oncogene-induced cell senescence STAT family protein binding endothelial to hematopoietic transition negative regulation of protein localization to chromatin DNA-binding transcription factor binding DNA-binding transcription factor binding protein sequestering activity positive regulation of p38MAPK cascade negative regulation of non-canonical NF-kappaB signal transduction apoptotic process involved in blood vessel morphogenesis positive regulation of miRNA transcription positive regulation of miRNA transcription positive regulation of microglial cell mediated cytotoxicity negative regulation of adipose tissue development pericyte cell differentiation positive regulation of antifungal innate immune response regulation of myeloid progenitor cell differentiation positive regulation of myeloid dendritic cell chemotaxis |
04380 05200 05221 |
| 1423130_a_at |
Srsf5 |
serine and arginine-rich splicing factor 5 |
12 |
80945498 |
AW212917 |
20384 |
43 |
mRNA splicing, via spliceosome nucleic acid binding RNA binding RNA binding protein binding nucleus nucleoplasm nucleolus cytosol mRNA processing RNA splicing response to wounding nuclear speck nuclear speck response to insulin positive regulation of RNA splicing protein kinase B binding RS domain binding |
03040 |
| 1423150_at |
Scg5 |
secretogranin V |
2 |
-113776312 |
AK019337 |
20394 |
54 |
enzyme inhibitor activity extracellular region nucleus intracellular protein transport neuropeptide signaling pathway peptide hormone processing secretory granule enzyme regulator activity regulation of hormone secretion regulation of hormone secretion unfolded protein binding |
|
| 1449393_at |
Sh2d1a |
SH2 domain containing 1A |
X |
42502564, 42505321 |
NM_011364 |
20400 |
141 |
adaptive immune response immune system process protein binding cytoplasm humoral immune response cellular defense response cell-cell signaling natural killer cell mediated cytotoxicity natural killer cell mediated cytotoxicity innate immune response positive regulation of natural killer cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity regulation of immune response negative regulation of T cell receptor signaling pathway |
04650 |
| 1452246_at |
Ostf1 |
osteoclast stimulating factor 1 |
19 |
-18580363 |
U58888 |
20409 |
34 |
cytoplasm signal transduction SH3 domain binding |
|
| 1416329_at |
Cyfip1 |
cytoplasmic FMR1 interacting protein 1 |
7 |
55842070 |
NM_011370 |
20430 |
73 |
RNA 7-methylguanosine cap binding RNA 7-methylguanosine cap binding cell morphogenesis actin binding protein binding profilin binding cytoplasm regulation of translation regulation of translation multicellular organism development nervous system development axon guidance regulation of cell shape positive regulation of lamellipodium assembly Rac protein signal transduction lamellipodium lamellipodium assembly lamellipodium assembly cell differentiation regulation of actin filament polymerization neuron projection development SCAR complex SCAR complex small GTPase binding regulation of myelination filopodium tip cellular response to insulin stimulus cell projection neuron projection neuron projection neuronal cell body terminal bouton dendritic spine dendritic growth cone axonal growth cone synapse synapse positive regulation of axon extension perinuclear region of cytoplasm axon extension positive regulation of axonogenesis cognition positive regulation of neurotrophin TRK receptor signaling pathway response to electrical stimulus excitatory synapse central region of growth cone peripheral region of growth cone dendrite extension postsynapse modification of synaptic structure modification of synaptic structure regulation of translation at postsynapse, modulating synaptic transmission regulation of translation at postsynapse, modulating synaptic transmission regulation of translation at postsynapse, modulating synaptic transmission regulation of translation at postsynapse, modulating synaptic transmission regulation of translation at postsynapse, modulating synaptic transmission positive regulation of dendrite development positive regulation of ruffle assembly negative regulation of synaptic vesicle recycling regulation of modification of postsynaptic actin cytoskeleton regulation of modification of postsynaptic actin cytoskeleton positive regulation of Arp2/3 complex-mediated actin nucleation |
04810 |
| 1420928_at |
St6gal1 |
beta galactoside alpha 2,6 sialyltransferase 1 |
16 |
23226020, 23290469, 23224739 |
BG075800 |
20440 |
87 |
Golgi trans cisterna Golgi membrane beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity extracellular region Golgi apparatus Golgi apparatus Golgi medial cisterna N-acetylneuraminate metabolic process protein glycosylation sialyltransferase activity sialyltransferase activity membrane transferase activity glycosyltransferase activity protein N-linked glycosylation via asparagine protein N-linked glycosylation via asparagine protein N-linked glycosylation via asparagine positive regulation of mononuclear cell proliferation protein homodimerization activity negative regulation of chemotaxis sialylation sialylation regulation of substrate adhesion-dependent cell spreading negative regulation of macrophage apoptotic process |
00510 00514 01100 |
| 1425668_a_at |
St3gal4 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
9 |
-35046575 |
AB061305 |
20443 |
50 |
beta-galactoside (CMP) alpha-2,3-sialyltransferase activity beta-galactoside (CMP) alpha-2,3-sialyltransferase activity beta-galactoside (CMP) alpha-2,3-sialyltransferase activity Golgi apparatus protein glycosylation protein glycosylation protein glycosylation lipid metabolic process N-acetyllactosaminide alpha-2,3-sialyltransferase activity N-acetyllactosaminide alpha-2,3-sialyltransferase activity sialyltransferase activity glycoprotein biosynthetic process glycolipid biosynthetic process glycolipid biosynthetic process oligosaccharide biosynthetic process membrane transferase activity glycosyltransferase activity positive regulation of blood coagulation lipid glycosylation beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase cognition sialylation positive regulation of leukocyte tethering or rolling positive regulation of leukocyte tethering or rolling protein sialylation |
00601 01100 |
| 1455695_at |
St8sia1 |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
6 |
-142821540 |
BI736113 |
20449 |
76 |
alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Golgi apparatus protein glycosylation protein glycosylation N-glycan processing lipid metabolic process sphingolipid metabolic process cell population proliferation sialyltransferase activity oligosaccharide metabolic process membrane transferase activity glycosyltransferase activity cellular response to heat epithelial cell proliferation positive regulation of epithelial cell proliferation |
00601 00603 00604 01100 |
| 1419186_a_at |
St8sia4 |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
1 |
-95587681, -95627242 |
NM_009183 |
20452 |
66 |
ganglioside biosynthetic process alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Golgi apparatus protein glycosylation protein glycosylation N-glycan processing N-glycan processing sialyltransferase activity oligosaccharide metabolic process oligosaccharide metabolic process membrane transferase activity glycosyltransferase activity sialylation sialylation |
|
| 1416206_at |
Sipa1 |
signal-induced proliferation associated gene 1 |
19 |
-5651184 |
D11374 |
20469 |
35 |
epithelial cell morphogenesis GTPase activator activity GTPase activator activity nucleus cytoplasm cytoplasm Golgi apparatus plasma membrane membrane protein-containing complex cellular response to water deprivation regulation of small GTPase mediated signal transduction regulation of cell cycle establishment of epithelial cell polarity |
04670 |
| 1418257_at |
Slc12a7 |
solute carrier family 12, member 7 |
13 |
73763696, 73763659 |
BB732135 |
20499 |
40 |
plasma membrane monoatomic ion transport potassium ion transport cell volume homeostasis cell volume homeostasis chemical synaptic transmission ammonium transmembrane transporter activity symporter activity potassium:chloride symporter activity potassium:chloride symporter activity membrane protein kinase binding transmembrane transporter activity protein-containing complex chloride ion homeostasis potassium ion homeostasis transmembrane transport cellular response to glucose stimulus potassium ion transmembrane transport ammonium import across plasma membrane chloride transmembrane transport potassium ion import across plasma membrane |
04966 |
| 1426599_a_at |
Slc2a1 |
solute carrier family 2 (facilitated glucose transporter), member 1 |
4 |
119108744 |
BM209618 |
20525 |
408 |
Golgi membrane female germ cell nucleus photoreceptor inner segment female pronucleus long-chain fatty acid transporter activity glucose transmembrane transporter activity glucose transmembrane transporter activity protein binding intracellular anatomical structure cytoplasm cytoplasm cytosol plasma membrane plasma membrane caveola cell-cell junction central nervous system development carbohydrate transport intercalated disc long-chain fatty acid import across plasma membrane membrane membrane basolateral plasma membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane apical plasma membrane apical plasma membrane kinase binding transmembrane transporter activity Z disc midbody cortical actin cytoskeleton vesicle response to insulin dehydroascorbic acid transmembrane transporter activity dehydroascorbic acid transmembrane transporter activity cellular response to glucose starvation sarcolemma identical protein binding xenobiotic transport xenobiotic transmembrane transporter activity protein self-association membrane raft synapse glucose import glucose import D-glucose transmembrane transporter activity D-glucose transmembrane transporter activity D-glucose transmembrane transporter activity transmembrane transport protein-containing complex assembly dehydroascorbic acid transport dehydroascorbic acid transport dehydroascorbic acid transport glucose import across plasma membrane presynapse transport across blood-brain barrier glucose transmembrane transport glucose transmembrane transport glucose transporter complex |
04920 04976 05200 05211 |
| 1455285_at |
Slc31a1 |
solute carrier family 31, member 1 |
4 |
62360700 |
BB771765 |
20529 |
64 |
angiogenesis angiogenesis copper ion transmembrane transporter activity copper ion transmembrane transporter activity copper ion transmembrane transporter activity copper ion binding protein binding endosome late endosome plasma membrane plasma membrane monoatomic ion transport copper ion transport intracellular copper ion homeostasis intercalated disc silver ion transmembrane transporter activity silver ion transmembrane transporter activity copper ion import copper ion import copper ion import plasma membrane copper ion transport membrane basolateral plasma membrane apical plasma membrane apical plasma membrane early endosome membrane copper ion transmembrane transport vascular endothelial growth factor receptor-2 signaling pathway identical protein binding xenobiotic transport xenobiotic transport xenobiotic transmembrane transporter activity neuronal cell body protein complex oligomerization establishment of localization in cell recycling endosome recycling endosome membrane transmembrane transport cellular response to cisplatin copper ion import across plasma membrane silver ion transmembrane transport silver ion transmembrane transport |
|
| 1416654_at |
Slc31a2 |
solute carrier family 31, member 2 |
4 |
62291546, 62286428 |
NM_025286 |
20530 |
25 |
protein binding lysosome lysosomal membrane endosome late endosome plasma membrane monoatomic ion transport intracellular copper ion homeostasis intracellular copper ion homeostasis copper ion import membrane cytoplasmic vesicle late endosome membrane recycling endosome regulation of copper ion transmembrane transport |
|
| 1417392_a_at |
Slc7a7 |
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 |
14 |
-54369441, -54369441, -54369441, -54369441, -54369441 |
NM_011405 |
20540 |
30 |
regulation of arginine metabolic process regulation of arginine metabolic process amino acid transmembrane transport plasma membrane amino acid transport basic amino acid transmembrane transporter activity basic amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity leucine transport membrane basolateral plasma membrane transmembrane transporter activity transmembrane transport L-arginine transmembrane transport basic amino acid transmembrane transport |
04974 |
| 1418612_at |
Slfn1 |
schlafen 1 |
11 |
83116819 |
NM_011407 |
20555 |
22 |
negative regulation of transcription by RNA polymerase II negative regulation of protein phosphorylation adaptive immune response immune system process RNA nuclease activity protein binding nucleus nucleus cytoplasm cytosol negative regulation of cell population proliferation T cell proliferation negative regulation of T cell proliferation ribosome binding regulation of cell cycle negative regulation of G1/S transition of mitotic cell cycle negative regulation of G1/S transition of mitotic cell cycle |
|
| 1427102_at |
Slfn4 |
schlafen 4 |
11 |
83175185 |
AF099975 |
20558 |
23 |
molecular_function RNA nuclease activity cellular_component nucleus cytosol response to bacterium ribosome binding |
|
| 1448377_at |
Slpi |
secretory leukocyte peptidase inhibitor |
2 |
-164354069 |
NM_011414 |
20568 |
66 |
immune system process DNA binding mRNA binding endopeptidase inhibitor activity endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity protein binding extracellular region extracellular space extracellular space extracellular space Golgi apparatus immune response negative regulation of peptidase activity antibacterial humoral response antibacterial humoral response antibacterial humoral response enzyme binding peptidase inhibitor activity negative regulation of protein binding response to lipopolysaccharide modulation of process of another organism defense response to bacterium negative regulation of viral genome replication innate immune response innate immune response |
|
| 1421052_a_at |
Sms |
spermine synthase |
X |
-157443850, -157443850 |
NM_009214 |
20603 |
33 |
polyamine biosynthetic process spermine biosynthetic process spermine biosynthetic process spermine metabolic process S-adenosylmethionine-dependent methyltransferase activity transferase activity spermine synthase activity spermine synthase activity |
00270 00330 00410 00480 01100 |
| 1429009_at |
Snrnp70 |
small nuclear ribonucleoprotein 70 (U1) |
7 |
-45376453 |
BI689977 |
20637 |
49 |
mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding mRNA binding nucleus nucleus nucleoplasm spliceosomal complex U1 snRNP U1 snRNP nuclear speck U1 snRNA binding U1 snRNA binding regulation of RNA splicing positive regulation of mRNA splicing, via spliceosome U2-type prespliceosome U1 snRNP binding ribonucleoprotein complex |
03040 |
| 1420952_at |
Son |
Son DNA binding protein |
16 |
91647823, 91647823 |
BB701473 |
20658 |
38 |
microtubule cytoskeleton organization mitotic cytokinesis nucleic acid binding DNA binding RNA binding RNA binding protein binding nucleus mRNA processing cell cycle RNA splicing nuclear speck negative regulation of apoptotic process regulation of RNA splicing regulation of mRNA splicing, via spliceosome regulation of mRNA splicing, via spliceosome RS domain binding regulation of cell cycle |
|
| 1453003_at |
Sorl1 |
sortilin-related receptor, LDLR class A repeats-containing |
9 |
-41964708, -41964708 |
AK013519 |
20660 |
87 |
amyloid-beta binding diet induced thermogenesis transmembrane signaling receptor activity protein binding extracellular region extracellular space extracellular space nuclear envelope lumen nuclear envelope lumen endosome early endosome multivesicular body endoplasmic reticulum Golgi apparatus Golgi apparatus trans-Golgi network plasma membrane protein targeting protein targeting protein targeting to lysosome protein targeting to lysosome post-Golgi vesicle-mediated transport post-Golgi vesicle-mediated transport endocytosis receptor-mediated endocytosis neuropeptide signaling pathway multicellular organism development cell surface negative regulation of triglyceride catabolic process regulation of smooth muscle cell migration membrane membrane cell migration aspartic-type endopeptidase inhibitor activity aspartic-type endopeptidase inhibitor activity low-density lipoprotein particle binding negative regulation of BMP signaling pathway small GTPase binding negative regulation of protein-containing complex assembly cytoplasmic vesicle Golgi cisterna protein localization to Golgi apparatus insulin receptor recycling insulin receptor recycling neuropeptide binding neuronal cell body protein retention in Golgi apparatus protein retention in Golgi apparatus protein retention in Golgi apparatus positive regulation of protein catabolic process positive regulation of insulin receptor signaling pathway positive regulation of insulin receptor signaling pathway perinuclear region of cytoplasm negative regulation of neurogenesis protein maturation recycling endosome positive regulation of protein exit from endoplasmic reticulum perinucleolar compartment endosome to plasma membrane protein transport positive regulation of glial cell-derived neurotrophic factor production positive regulation of glial cell-derived neurotrophic factor production negative regulation of amyloid-beta formation negative regulation of amyloid-beta formation positive regulation of ER to Golgi vesicle-mediated transport positive regulation of early endosome to recycling endosome transport positive regulation of protein localization to early endosome negative regulation of amyloid precursor protein catabolic process negative regulation of amyloid precursor protein catabolic process negative regulation of neurofibrillary tangle assembly positive regulation of adipose tissue development positive regulation of adipose tissue development adaptive thermogenesis positive regulation of endocytic recycling |
|
| 1433575_at |
Sox4 |
SRY (sex determining region Y)-box 4 |
13 |
-28948919 |
BG083485 |
20677 |
201 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific pro-B cell differentiation mitral valve morphogenesis cardiac right ventricle morphogenesis atrial septum primum morphogenesis noradrenergic neuron differentiation DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex cytoplasm cytoplasm mitochondrion regulation of DNA-templated transcription regulation of DNA-templated transcription nervous system development brain development heart development positive regulation of cell population proliferation negative regulation of cell population proliferation gene expression glial cell proliferation spinal cord development glial cell development neuron differentiation T cell differentiation endocrine pancreas development negative regulation of protein ubiquitination regulation of protein stability positive regulation of insulin secretion somatic stem cell population maintenance miRNA binding ascending aorta morphogenesis glucose homeostasis positive regulation of apoptotic process regulation of DNA damage response, signal transduction by p53 class mediator positive regulation of gamma-delta T cell differentiation negative regulation of myoblast differentiation positive regulation of myoblast differentiation positive regulation of myoblast differentiation positive regulation of translation positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II sympathetic nervous system development camera-type eye morphogenesis protein stabilization protein stabilization ventricular septum morphogenesis mesenchyme development neuroepithelial cell differentiation kidney morphogenesis hematopoietic stem cell homeostasis cellular response to glucose stimulus positive regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway sequence-specific double-stranded DNA binding positive regulation of N-terminal peptidyl-lysine acetylation |
|
| 1424923_at |
Serpina3g |
serine (or cysteine) peptidase inhibitor, clade A, member 3G |
12 |
104236146, 104214453 |
BC002065 |
20715 |
30 |
adaptive immune response immune system process serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity extracellular space extracellular space nucleus cytoplasm apoptotic process negative regulation of peptidase activity negative regulation of endopeptidase activity peptidase inhibitor activity response to cytokine response to peptide hormone |
|
| 1456615_a_at |
Bptf |
bromodomain PHD finger transcription factor |
11 |
-107033080 |
AA867746 |
207165 |
58 |
negative regulation of transcription by RNA polymerase II chromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding embryonic placenta development nucleus nucleus nucleoplasm chromatin remodeling regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II brain development brain development endoderm development ATP-dependent activity, acting on DNA transcription factor binding anterior/posterior pattern specification NURF complex NURF complex dendrite methylated histone binding sequence-specific DNA binding cell body positive regulation of transcription by RNA polymerase II perinuclear region of cytoplasm ATPase complex |
|
| 1422601_at |
Serpinb9 |
serine (or cysteine) peptidase inhibitor, clade B, member 9 |
13 |
33004540 |
NM_009256 |
20723 |
41 |
T cell mediated cytotoxicity protease binding acute inflammatory response to antigenic stimulus serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity protein binding extracellular space extracellular space nucleus nucleoplasm cytoplasm cytoplasm cytoplasm Golgi apparatus cytosol immune response negative regulation of endopeptidase activity negative regulation of endopeptidase activity protection from natural killer cell mediated cytotoxicity defense response to bacterium cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process collagen-containing extracellular matrix negative regulation of T cell apoptotic process |
05146 |
| 1434260_at |
Fchsd2 |
FCH and double SH3 domains 2 |
7 |
101108774 |
BB461848 |
207278 |
20 |
protein binding phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm plasma membrane clathrin-coated pit endocytosis neuromuscular synaptic transmission lipid binding protein transport membrane regulation of actin filament polymerization positive regulation of actin filament polymerization neuromuscular junction cell projection phosphatidylinositol-3,4-bisphosphate binding recycling endosome membrane organization anchoring junction clathrin-dependent endocytosis stereocilium shaft positive regulation of Arp2/3 complex-mediated actin nucleation |
|
| 1415794_a_at |
Spin1 |
spindlin 1 |
13 |
51134317, 51100879, 51101546 |
BM228780 |
20729 |
40 |
DNA binding nucleus nucleoplasm nucleoplasm nucleolus cytoplasm spindle cytosol cytosol cytoskeleton chromatin organization regulation of DNA-templated transcription cell cycle female meiotic nuclear division multicellular organism development gamete generation rRNA transcription Wnt signaling pathway positive regulation of Wnt signaling pathway nuclear membrane methylated histone binding methylated histone binding positive regulation of DNA-templated transcription meiotic cell cycle |
|
| 1438968_x_at |
Spint2 |
serine protease inhibitor, Kunitz type 2 |
7 |
-29256329 |
AV058358 |
20733 |
44 |
neural tube closure neural tube closure serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity cytoplasm plasma membrane establishment or maintenance of cell polarity negative regulation of peptidase activity membrane negative regulation of cell-cell adhesion peptidase inhibitor activity epithelial cell morphogenesis involved in placental branching epithelial cell morphogenesis involved in placental branching basement membrane organization negative regulation of cell motility negative regulation of neural precursor cell proliferation |
|
| 1426411_a_at |
Strbp |
spermatid perinuclear RNA binding protein |
2 |
-37569867, -37569867, -37569867, -37569867 |
AK006314 |
20744 |
32 |
manchette RNA binding double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding nucleus cytoplasm cytoskeleton multicellular organism development spermatogenesis spermatid development mechanosensory behavior microtubule binding microtubule cytoskeleton tubulin binding cell differentiation cell motility |
|
| 1449254_at |
Spp1 |
secreted phosphoprotein 1 |
5 |
104435110, 104436191 |
NM_009263 |
20750 |
938 |
ossification osteoblast differentiation osteoblast differentiation cytokine activity integrin binding integrin binding extracellular region extracellular space extracellular space cytoplasm Golgi apparatus androgen catabolic process intracellular calcium ion homeostasis intracellular sodium ion homeostasis cell adhesion cell adhesion response to organic substance positive regulation of cell-substrate adhesion bone mineralization bone mineralization neutrophil chemotaxis neutrophil chemotaxis intracellular phosphate ion homeostasis intracellular chloride ion homeostasis biomineral tissue development vesicle response to vitamin D urate biosynthetic process small molecule binding cell projection negative regulation of apoptotic process ion binding apical part of cell positive regulation of bone resorption positive regulation of bone resorption positive regulation of DNA-templated transcription perinuclear region of cytoplasm response to steroid hormone extracellular matrix binding extracellular matrix binding calcium ion homeostasis cellular response to testosterone stimulus cellular response to fluid shear stress collecting duct development cellular response to leukemia inhibitory factor positive regulation of estradiol secretion |
04510 04512 04620 |
| 1437378_x_at |
Scarb1 |
scavenger receptor class B, member 1 |
5 |
-125277086, -125283319 |
BB224405 |
20778 |
393 |
lipopolysaccharide binding amyloid-beta binding phosphatidylserine binding lipopolysaccharide immune receptor activity endothelial cell proliferation scavenger receptor activity cytoplasm cytoplasm lysosome plasma membrane plasma membrane plasma membrane plasma membrane caveola caveola androgen biosynthetic process cholesterol catabolic process cholesterol catabolic process lipid transport phagocytosis, recognition high-density lipoprotein particle binding lipid binding cell surface cell surface positive regulation of triglyceride biosynthetic process positive regulation of cholesterol storage positive regulation of cholesterol storage regulation of phosphatidylcholine catabolic process phospholipid transport lipopolysaccharide transport membrane low-density lipoprotein particle binding low-density lipoprotein particle binding low-density lipoprotein particle binding cholesterol transport cholesterol transport microvillus membrane detection of lipopolysaccharide cholesterol efflux cholesterol efflux cholesterol efflux cholesterol efflux apolipoprotein binding apolipoprotein binding apolipoprotein A-I binding high-density lipoprotein particle remodeling plasma lipoprotein particle clearance low-density lipoprotein particle clearance high-density lipoprotein particle clearance high-density lipoprotein particle clearance vitamin transmembrane transport cholesterol homeostasis identical protein binding intracellular membrane-bounded organelle blood vessel endothelial cell migration recognition of apoptotic cell recognition of apoptotic cell recognition of apoptotic cell reverse cholesterol transport adhesion of symbiont to host carotenoid transport regulation of phagocytosis positive regulation of nitric-oxide synthase activity triglyceride homeostasis high-density lipoprotein particle receptor activity high-density lipoprotein particle receptor activity cholesterol import cholesterol import cholesterol import cholesterol import intestinal lipid absorption |
04145 04975 04976 04977 05160 |
| 1428681_at |
Usf3 |
upstream transcription factor family member 3 |
16 |
44173396 |
AK017426 |
207806 |
16 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific negative regulation of epithelial to mesenchymal transition negative regulation of epithelial to mesenchymal transition positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II |
|
| 1456500_at |
Aph1b |
aph1 homolog B, gamma secretase subunit |
9 |
-66775486 |
AV232784 |
208117 |
35 |
Golgi membrane synaptic transmission, dopaminergic endoplasmic reticulum endoplasmic reticulum plasma membrane membrane protein ectodomain proteolysis Notch signaling pathway Notch signaling pathway Notch receptor processing Notch receptor processing Notch receptor processing short-term memory locomotory behavior positive regulation of endopeptidase activity membrane protein processing protein processing transport vesicle protein-macromolecule adaptor activity protein-macromolecule adaptor activity amyloid-beta formation amyloid-beta formation synaptic transmission, glutamatergic amyloid precursor protein catabolic process positive regulation of catalytic activity prepulse inhibition endopeptidase activator activity gamma-secretase complex gamma-secretase complex gamma-secretase complex gamma-secretase complex |
04330 05010 |
| 1455107_at |
Srpk1 |
serine/arginine-rich protein specific kinase 1 |
17 |
-28589587 |
BQ176926 |
20815 |
38 |
nucleotide binding spliceosomal complex assembly magnesium ion binding magnesium ion binding chromatin protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding ATP binding nucleus nucleus nucleoplasm nucleoplasm chromosome cytoplasm cytoplasm endoplasmic reticulum cytosol plasma membrane mRNA processing protein phosphorylation protein phosphorylation chromosome segregation RNA splicing kinase activity phosphorylation nuclear speck transferase activity peptidyl-serine phosphorylation cell differentiation intracellular signal transduction intracellular signal transduction intracellular signal transduction intracellular membrane-bounded organelle positive regulation of viral genome replication negative regulation of viral genome replication regulation of mRNA processing regulation of mRNA processing regulation of mRNA processing protein serine kinase activity |
|
| 1455656_at |
Btla |
B and T lymphocyte associated |
16 |
45224336 |
BM240873 |
208154 |
80 |
adaptive immune response immune system process immune response-regulating cell surface receptor signaling pathway immune response-regulating cell surface receptor signaling pathway protein binding plasma membrane plasma membrane cell surface receptor signaling pathway external side of plasma membrane membrane negative regulation of B cell proliferation signaling receptor activity signaling receptor activity negative regulation of T cell proliferation negative regulation of alpha-beta T cell proliferation |
|
| 1450033_a_at |
Stat1 |
signal transducer and activator of transcription 1 |
1 |
52119437, 52119621 |
AW214029 |
20846 |
996 |
chromatin RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription corepressor binding transcription coactivator binding negative regulation of endothelial cell proliferation positive regulation of defense response to virus by host DNA binding double-stranded DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity tumor necrosis factor receptor binding protein binding nucleus nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytoplasm cytosol cytosol DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II activation of cysteine-type endopeptidase activity involved in apoptotic process defense response signal transduction receptor signaling pathway via JAK-STAT receptor signaling pathway via JAK-STAT receptor signaling pathway via JAK-STAT cell population proliferation response to bacterium macrophage derived foam cell differentiation negative regulation of angiogenesis nuclear receptor binding cytokine-mediated signaling pathway enzyme binding axon dendrite lipopolysaccharide-mediated signaling pathway CCR5 chemokine receptor binding response to lipopolysaccharide positive regulation of interferon-alpha production protein-containing complex tumor necrosis factor-mediated signaling pathway negative regulation of macrophage fusion response to type I interferon response to type II interferon response to type II interferon histone acetyltransferase binding response to interferon-beta cellular response to interferon-beta interleukin-9-mediated signaling pathway regulation of cell population proliferation histone binding identical protein binding protein homodimerization activity negative regulation of canonical NF-kappaB signal transduction response to exogenous dsRNA response to peptide hormone sequence-specific DNA binding ubiquitin-like protein ligase binding positive regulation of erythrocyte differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II negative regulation by virus of viral protein levels in host cell perinuclear region of cytoplasm defense response to virus defense response to virus protein phosphatase 2A binding type II interferon-mediated signaling pathway type II interferon-mediated signaling pathway type I interferon-mediated signaling pathway type I interferon-mediated signaling pathway type I interferon-mediated signaling pathway renal tubule development interleukin-27-mediated signaling pathway ISGF3 complex cellular response to lipopolysaccharide cellular response to cytokine stimulus cellular response to type II interferon cellular response to organic cyclic compound RNA polymerase II transcription regulator complex promoter-specific chromatin binding |
04062 04380 04620 04630 05140 05145 05160 05200 05212 |
| 1450403_at |
Stat2 |
signal transducer and activator of transcription 2 |
10 |
128270497 |
AF088862 |
20847 |
139 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific regulation of protein phosphorylation DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus cytoplasm cytosol plasma membrane regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II defense response signal transduction receptor signaling pathway via JAK-STAT receptor signaling pathway via JAK-STAT regulation of cell population proliferation identical protein binding response to peptide hormone ubiquitin-like protein ligase binding positive regulation of transcription by RNA polymerase II defense response to virus type I interferon-mediated signaling pathway type I interferon-mediated signaling pathway type I interferon-mediated signaling pathway negative regulation of type I interferon-mediated signaling pathway negative regulation of type I interferon-mediated signaling pathway ISGF3 complex regulation of mitochondrial fission |
04062 04380 04630 05160 |
| 1442083_at |
Rsrc2 |
arginine/serine-rich coiled-coil 2 |
5 |
-123728425 |
BB036922 |
208606 |
22 |
molecular_function cellular_component biological_process |
|
| 1419709_at |
Stfa3 |
stefin A3 |
16 |
-36450536 |
NM_025288 |
20863 |
16 |
cornified envelope protease binding cysteine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity extracellular space nucleoplasm cytoplasm cytosol cytosol negative regulation of peptidase activity peptide cross-linking keratinocyte differentiation negative regulation of proteolysis cell-cell adhesion peptidase inhibitor complex |
|
| 1427983_at |
Zfp280c |
zinc finger protein 280C |
X |
-48541625, -48541625 |
AI504060 |
208968 |
18 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus regulation of DNA-templated transcription metal ion binding |
|
| 1437390_x_at |
Stx1a |
syntaxin 1A (brain) |
5 |
135023481 |
AV339210 |
20907 |
209 |
SNARE binding SNARE binding SNARE binding acrosomal vesicle positive regulation of neurotransmitter secretion positive regulation of neurotransmitter secretion SNAP receptor activity SNAP receptor activity protein binding plasma membrane plasma membrane plasma membrane plasma membrane neurotransmitter transport intracellular protein transport intracellular protein transport exocytosis exocytosis synaptic vesicle synaptic vesicle voltage-gated potassium channel complex response to gravity positive regulation of norepinephrine secretion regulation of synaptic vesicle priming endomembrane system postsynaptic density membrane synaptic vesicle exocytosis synaptic vesicle exocytosis synaptic vesicle exocytosis vesicle-mediated transport protein sumoylation myosin binding calcium-ion regulated exocytosis regulation of exocytosis calcium channel inhibitor activity chloride channel inhibitor activity kinase binding insulin secretion secretory granule axon synaptic vesicle membrane synaptic vesicle membrane protein-macromolecule adaptor activity SNARE complex SNARE complex cytoplasmic vesicle synaptic vesicle fusion to presynaptic active zone membrane synaptic vesicle fusion to presynaptic active zone membrane nuclear membrane myosin head/neck binding secretion by cell protein-containing complex positive regulation of catecholamine secretion SNARE complex assembly actomyosin presynaptic membrane identical protein binding neuron projection neuron projection ATP-dependent protein binding transmembrane transporter binding protein-containing complex binding regulated exocytosis synapse positive regulation of exocytosis positive regulation of calcium ion-dependent exocytosis hormone secretion vesicle docking vesicle docking calcium-dependent protein binding synaptic vesicle endocytosis presynaptic active zone membrane presynaptic active zone membrane synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex synaptobrevin 2-SNAP-25-syntaxin-1a complex synaptobrevin 2-SNAP-25-syntaxin-1a complex protein localization to membrane Schaffer collateral - CA1 synapse presynapse modulation of excitatory postsynaptic potential postsynaptic density membrane glutamatergic synapse positive regulation of excitatory postsynaptic potential |
04130 |
| 1456479_at |
Snx30 |
sorting nexin family member 30 |
4 |
59805649 |
BB359719 |
209131 |
16 |
phagophore assembly site autophagy of mitochondrion cytoplasm endosome early endosome early endosome protein transport protein transport membrane endocytic recycling piecemeal microautophagy of the nucleus phosphatidylinositol binding reticulophagy positive regulation of autophagosome assembly |
|
| 1439825_at |
Dtx3l |
deltex 3-like, E3 ubiquitin ligase |
16 |
-35926514 |
BB705351 |
209200 |
19 |
DNA damage checkpoint signaling positive regulation of defense response to virus by host immune system process ubiquitin-protein transferase activity enzyme inhibitor activity nucleus nucleoplasm cytoplasm lysosome endosome early endosome cytosol DNA repair double-strand break repair chromatin organization ubiquitin-dependent protein catabolic process DNA damage response Notch signaling pathway endosome to lysosome transport protein transport membrane protein ubiquitination transferase activity enzyme binding positive regulation of protein binding protein-containing complex positive regulation of chromatin binding histone binding ubiquitin-like protein ligase binding innate immune response positive regulation of DNA-templated transcription metal ion binding negative regulation of ubiquitin-protein transferase activity defense response to virus protein autoubiquitination protein K48-linked ubiquitination STAT family protein binding protein ADP-ribosyltransferase-substrate adaptor activity histone ubiquitin ligase activity DNA repair-dependent chromatin remodeling histone H4K91 ubiquitin ligase activity positive regulation of protein localization to nucleus positive regulation of protein localization to early endosome positive regulation of receptor catabolic process |
04330 |
| 1435665_at |
Trim30d |
tripartite motif-containing 30D |
7 |
-104470013 |
BM241342 |
209387 |
13 |
protein polyubiquitination P-body activation of innate immune response transcription coactivator activity ubiquitin-protein transferase activity nucleoplasm cytoplasm cytoplasm cytosol autophagy positive regulation of autophagy protein kinase binding protein kinase binding protein-macromolecule adaptor activity regulation of lipopolysaccharide-mediated signaling pathway regulation of protein localization regulation of protein localization pattern recognition receptor activity identical protein binding protein homodimerization activity protein homodimerization activity positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of MAPK cascade suppression of viral release by host innate immune response innate immune response regulation of viral entry into host cell negative regulation of viral entry into host cell positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity ubiquitin protein ligase activity protein K63-linked ubiquitination omegasome |
|
| 1423543_at |
Swap70 |
SWA-70 protein |
7 |
110221702 |
AK019882 |
20947 |
65 |
DNA binding protein binding ATP binding nucleus nucleus cytoplasm cytoplasm cytoskeleton plasma membrane positive regulation of cytosolic calcium ion concentration regulation of actin polymerization or depolymerization actin cytoskeleton membrane somatic cell DNA recombination negative regulation of actin filament depolymerization positive regulation of actin filament bundle assembly regulation of protein localization negative regulation of cell-cell adhesion mediated by integrin cell projection isotype switching actin filament bundle assembly positive regulation of mast cell chemotaxis negative regulation of peptidyl-serine dephosphorylation |
|
| 1424356_a_at |
Metrnl |
meteorin, glial cell differentiation regulator-like |
11 |
121702426 |
BC024445 |
210029 |
41 |
hormone activity hormone activity extracellular region extracellular space extracellular space extracellular space response to cold response to muscle activity fat cell differentiation negative regulation of inflammatory response brown fat cell differentiation positive regulation of brown fat cell differentiation positive regulation of brown fat cell differentiation energy homeostasis energy homeostasis |
|
| 1435343_at |
Dock10 |
dedicator of cytokinesis 10 |
1 |
-80501067, -80501067 |
BF715043 |
210293 |
32 |
B cell homeostasis marginal zone B cell differentiation guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity nucleus nucleoplasm cytoplasm cytosol small GTPase-mediated signal transduction regulation of cell migration regulation of cell migration small GTPase binding cell projection dendritic spine positive regulation of GTPase activity positive regulation of GTPase activity synapse dendritic spine morphogenesis dendritic spine morphogenesis postsynapse postsynapse glutamatergic synapse glutamatergic synapse |
|
| 1436423_at |
Themis |
thymocyte selection associated |
10 |
28668359, 28668359, 28668394 |
BE628523 |
210757 |
42 |
adaptive immune response immune system process protein binding nucleus nucleus cytoplasm cytoplasm cell-cell junction multicellular organism development COP9 signalosome positive T cell selection negative T cell selection T cell receptor signaling pathway T cell receptor signaling pathway |
|
| 1435545_at |
Bicral |
BRD4 interacting chromatin remodeling complex associated protein like |
17 |
-46798115 |
BB242234 |
210982 |
21 |
chromatin chromatin remodeling regulation of transcription by RNA polymerase II positive regulation of cell population proliferation SWI/SNF complex SWI/SNF complex SWI/SNF complex negative regulation of cell differentiation positive regulation of DNA-templated transcription GBAF complex positive regulation of stem cell population maintenance |
|
| 1442135_at |
Ado |
2-aminoethanethiol dioxygenase |
10 |
-67544510 |
AA839814 |
211488 |
20 |
iron ion binding iron ion binding iron ion binding protein binding mitochondrion oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen metal ion binding cysteamine dioxygenase activity cysteamine dioxygenase activity dioxygenase activity cellular response to hypoxia |
00430 01100 |
| 1437253_at |
Dennd6a |
DENN domain containing 6A |
14 |
26573857, 26579549, 26579549 |
BB235551 |
211922 |
18 |
guanyl-nucleotide exchange factor activity cytoplasm endosome intracellular membrane-bounded organelle recycling endosome recycling endosome positive regulation of cell-cell adhesion mediated by cadherin |
|
| 1451234_at |
Fam193b |
family with sequence similarity 193, member B |
13 |
-55539315 |
BC021381 |
212483 |
18 |
molecular_function nucleus nucleus nucleoplasm nucleolus cytoplasm cytoplasm cytoplasm biological_process nuclear speck |
|
| 1436397_at |
Tifab |
TRAF-interacting protein with forkhead-associated domain, family member B |
13 |
-56173702 |
BB040051 |
212937 |
14 |
toll-like receptor signaling pathway hematopoietic progenitor cell differentiation canonical NF-kappaB signal transduction thorax and anterior abdomen determination regulation of gene expression trigeminal nerve development vestibulocochlear nerve formation myeloid cell differentiation myeloid cell differentiation peristalsis auditory behavior lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway genitalia morphogenesis deubiquitinase activator activity inner ear morphogenesis regulation of muscle organ development genitalia development inner ear development neuromuscular process controlling balance mastication cochlea development cochlea morphogenesis craniofacial suture morphogenesis learned vocalization behavior negative regulation of relaxation of muscle regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator negative regulation of saliva secretion hard palate morphogenesis |
|
| 1440865_at |
Ifitm6 |
interferon induced transmembrane protein 6 |
7 |
-141015811 |
BB193024 |
213002 |
19 |
molecular_function plasma membrane response to type II interferon response to interferon-alpha response to interferon-beta negative regulation of viral genome replication negative regulation of viral entry into host cell defense response to virus type I interferon-mediated signaling pathway |
|
| 1455110_at |
Gabpb2 |
GA repeat binding protein, beta 2 |
3 |
-95181765 |
AW536205 |
213054 |
28 |
transcription cis-regulatory region binding transcription cis-regulatory region binding nucleus nucleus identical protein binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II |
|
| 1447792_x_at |
Gpr174 |
G protein-coupled receptor 174 |
X |
107255877, 107284345 |
BB241847 |
213439 |
22 |
G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane centriolar satellite positive regulation of Rho protein signal transduction T cell homeostasis intracellular membrane-bounded organelle bioactive lipid receptor activity |
|
| 1455042_at |
Tbl1x |
transducin (beta)-like 1 X-linked |
X |
77511226 |
BF682509 |
21372 |
41 |
histone deacetylase complex histone deacetylase complex transcription cis-regulatory region binding transcription cis-regulatory region binding DNA binding chromatin binding transcription corepressor activity transcription corepressor activity transcription corepressor activity protein binding nucleus nucleoplasm nucleoplasm transcription regulator complex regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription repressor complex histone binding identical protein binding proteasome-mediated ubiquitin-dependent protein catabolic process response to estrogen fat cell differentiation negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II response to steroid hormone protein stabilization mitotic spindle |
04310 |
| 1427670_a_at |
Tcf12 |
transcription factor 12 |
9 |
-71844251, -71844251, -71844251 |
M97636 |
21406 |
137 |
chromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm transcription regulator complex transcription regulator complex cytoplasm regulation of transcription by RNA polymerase II multicellular organism development nervous system development gene expression positive regulation of gene expression nuclear speck cell differentiation cAMP response element binding intracellular membrane-bounded organelle bHLH transcription factor binding positive regulation of neuron differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II SMAD binding protein heterodimerization activity protein dimerization activity E-box binding HMG box domain binding RNA polymerase II transcription regulator complex response to gonadotropin-releasing hormone DNA-binding transcription factor binding sequence-specific double-stranded DNA binding |
|
| 1434148_at |
Tcf4 |
transcription factor 4 |
18 |
69345720, 69344491, 69346159 |
BB364520 |
21413 |
241 |
negative regulation of transcription by RNA polymerase II chromatin RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific TFIIB-class transcription factor binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA binding chromatin binding double-stranded DNA binding DNA-binding transcription factor activity transcription corepressor activity protein binding nucleus nucleus transcription regulator complex transcription regulator complex regulation of DNA-templated transcription regulation of transcription by RNA polymerase II multicellular organism development nervous system development beta-catenin binding negative regulation of gene expression negative regulation of angiogenesis cell differentiation endothelial cell activation identical protein binding bHLH transcription factor binding protein self-association positive regulation of neuron differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein heterodimerization activity protein dimerization activity protein-DNA complex assembly beta-catenin-TCF7L2 complex E-box binding regulation of vascular endothelial growth factor signaling pathway sequence-specific double-stranded DNA binding beta-catenin-TCF complex |
|
| 1433471_at |
Tcf7 |
transcription factor 7, T cell specific |
11 |
-52252282, -52252282 |
AI323642 |
21414 |
282 |
negative regulation of transcription by RNA polymerase II euchromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II beta-catenin binding Wnt signaling pathway nuclear body neural tube development embryonic genitalia morphogenesis T cell receptor V(D)J recombination regulation of cell population proliferation gamma-delta T cell differentiation negative regulation of apoptotic process canonical Wnt signaling pathway involved in negative regulation of apoptotic process regulation of gamma-delta T cell differentiation alpha-beta T cell differentiation embryonic digestive tract morphogenesis embryonic hindgut morphogenesis canonical Wnt signaling pathway canonical Wnt signaling pathway cellular response to interleukin-4 sequence-specific double-stranded DNA binding beta-catenin-TCF complex |
04310 04520 04916 05200 05210 05213 05215 05216 05217 05221 05412 |
| 1429428_at |
Tcf7l2 |
transcription factor 7 like 2, T cell specific, HMG box |
19 |
55741809, 55895320 |
BB175494 |
21416 |
286 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development intracellular glucose homeostasis in utero embryonic development DNA binding chromatin binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex cytosol glycogen metabolic process glucose metabolic process regulation of gluconeogenesis regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II beta-catenin binding beta-catenin binding beta-catenin binding fibroblast growth factor receptor signaling pathway cellular response to starvation response to glucose post-embryonic development positive regulation of epithelial to mesenchymal transition positive regulation of triglyceride biosynthetic process positive regulation of heparan sulfate proteoglycan biosynthetic process oligodendrocyte development Wnt signaling pathway nuclear receptor binding protein kinase binding neural tube development pituitary gland development bone mineralization BMP signaling pathway negative regulation of BMP signaling pathway embryonic genitalia morphogenesis regulation of myelination positive regulation of insulin secretion positive regulation of insulin secretion positive regulation of protein binding secretory granule localization regulation of hormone metabolic process protein-DNA complex somatic stem cell population maintenance somatic stem cell population maintenance multicellular organism growth organ growth negative regulation of fibroblast growth factor receptor signaling pathway odontogenesis of dentin-containing tooth glucose homeostasis glucose homeostasis positive regulation of apoptotic process negative regulation of DNA-binding transcription factor activity sequence-specific DNA binding sequence-specific DNA binding maintenance of DNA repeat elements skin development gamma-catenin binding fat cell differentiation negative regulation of fat cell differentiation negative regulation of gluconeogenesis positive regulation of gluconeogenesis negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of organ growth positive regulation of lipid biosynthetic process embryonic digestive tract morphogenesis embryonic hindgut morphogenesis myoblast fate commitment myoblast fate commitment regulation of skeletal muscle tissue development regulation of smooth muscle cell proliferation regulation of oligodendrocyte differentiation epithelial cell proliferation positive regulation of epithelial cell proliferation positive regulation of epithelial cell proliferation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway face morphogenesis regulation of insulin secretion involved in cellular response to glucose stimulus regulation of insulin secretion involved in cellular response to glucose stimulus RNA polymerase II-specific DNA-binding transcription factor binding armadillo repeat domain binding beta-catenin-TCF7L2 complex catenin-TCF7L2 complex catenin-TCF7L2 complex negative regulation of canonical Wnt signaling pathway positive regulation of protein localization to nucleus insulin metabolic process promoter-specific chromatin binding beta-catenin-TCF complex negative regulation of type B pancreatic cell apoptotic process negative regulation of extrinsic apoptotic signaling pathway |
04310 04520 04916 05200 05210 05213 05215 05216 05217 05221 05412 |
| 1452377_at |
Kmt2a |
lysine (K)-specific methyltransferase 2A |
9 |
-44803354 |
AK017541 |
214162 |
226 |
DNA binding chromatin binding protein binding nucleus nucleus nucleoplasm cytosol DNA methylation chromatin organization regulation of DNA-templated transcription methyltransferase activity zinc ion binding visual learning response to light stimulus post-embryonic development anterior/posterior pattern specification anterior/posterior pattern specification regulation of gene expression positive regulation of gene expression transferase activity peptidyl-lysine monomethylation methylation circadian regulation of gene expression histone methyltransferase complex histone methyltransferase complex embryonic hemopoiesis exploration behavior protein modification process histone H3K4 methyltransferase activity histone H3K4 methyltransferase activity histone H3K4 methyltransferase activity histone H3K4 methyltransferase activity identical protein binding protein homodimerization activity T-helper 2 cell differentiation unmethylated CpG binding transcription initiation-coupled chromatin remodeling positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding fibroblast proliferation negative regulation of fibroblast proliferation regulation of short-term neuronal synaptic plasticity rhythmic process spleen development homeostasis of number of cells within a tissue cognition definitive hemopoiesis protein-containing complex assembly lysine-acetylated histone binding MLL1 complex cellular response to transforming growth factor beta stimulus negative regulation of DNA methylation-dependent heterochromatin formation protein-cysteine methyltransferase activity DNA-binding transcription factor binding histone H3K4 monomethyltransferase activity histone H3K4 trimethyltransferase activity |
|
| 1426297_at |
Tcf3 |
transcription factor 3 |
10 |
-80409540 |
AF352579 |
21423 |
346 |
negative regulation of transcription by RNA polymerase II chromatin nucleosome euchromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific natural killer cell differentiation B cell lineage commitment DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex transcription regulator complex transcription regulator complex transcription regulator complex cytoplasm cytosol chromatin remodeling regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II gastrulation nervous system development response to xenobiotic stimulus gene expression positive regulation of gene expression positive regulation of gene expression lymphocyte differentiation cell differentiation PDZ domain binding erythrocyte differentiation positive regulation of B cell proliferation mitogen-activated protein kinase kinase kinase binding response to lipopolysaccharide protein-containing complex T cell differentiation in thymus immunoglobulin V(D)J recombination immunoglobulin V(D)J recombination immunoglobulin V(D)J recombination identical protein binding protein homodimerization activity bHLH transcription factor binding bHLH transcription factor binding sequence-specific DNA binding sequence-specific DNA binding positive regulation of neuron differentiation positive regulation of cell cycle positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein heterodimerization activity protein heterodimerization activity protein dimerization activity cell development Peyer's patch development protein stabilization positive regulation of DNA-binding transcription factor activity RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II-specific DNA-binding transcription factor binding vitamin D response element binding E-box binding E-box binding E-box binding RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex DNA-binding transcription factor binding regulation of G1/S transition of mitotic cell cycle |
|
| 1419537_at |
Tfec |
transcription factor EC |
6 |
-16833380 |
NM_031198 |
21426 |
34 |
negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding nucleus nucleus nucleoplasm cytosol regulation of DNA-templated transcription regulation of transcription by RNA polymerase II cellular response to heat positive regulation of transcription by RNA polymerase II protein dimerization activity sequence-specific double-stranded DNA binding |
|
| 1434339_at |
Fnbp1l |
formin binding protein 1-like |
3 |
-122538718 |
AW548221 |
214459 |
30 |
cytoplasm cytosol cytoskeleton plasma membrane endocytosis vesicle budding from membrane autophagy signal transduction lipid binding membrane invagination membrane vesicle organization vesicle transport along actin filament cytoplasmic vesicle GTPase binding positive regulation of filopodium assembly cilium assembly clathrin-dependent endocytosis plasma membrane tubulation |
|
| 1457825_x_at |
Tcn2 |
transcobalamin 2 |
11 |
-3917079, -3917077, -3917079 |
BB515151 |
21452 |
40 |
extracellular region extracellular space extracellular space extracellular space extracellular space monoatomic ion transport cobalt ion transport external side of plasma membrane cobalamin transport cobalamin transport cobalamin transport cobalamin binding cobalamin binding cobalamin binding metal ion binding molecular carrier activity cargo receptor ligand activity cargo receptor ligand activity |
04977 |
| 1444003_at |
Neurl3 |
neuralized E3 ubiquitin protein ligase 3 |
1 |
-36264601 |
AW610818 |
214854 |
18 |
immune system process cytoplasm early endosome protein ubiquitination transferase activity innate immune response metal ion binding ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin-dependent endocytosis |
|
| 1437105_at |
Kdm5a |
lysine demethylase 5A |
6 |
120364098 |
BM246184 |
214899 |
59 |
negative regulation of transcription by RNA polymerase II chromatin transcription cis-regulatory region binding DNA binding chromatin binding transcription coactivator activity enzyme inhibitor activity protein binding nucleus nucleus nucleus nucleoplasm chromatin organization chromatin remodeling regulation of DNA-templated transcription multicellular organism development zinc ion binding oxidoreductase activity chromatin DNA binding histone H3K4 demethylase activity circadian regulation of gene expression protein-DNA complex histone H3K4me/H3K4me2/H3K4me3 demethylase activity histone H3K4me/H3K4me2/H3K4me3 demethylase activity methylated histone binding histone binding positive regulation of DNA-templated transcription metal ion binding rhythmic process regulation of DNA-binding transcription factor activity dioxygenase activity facultative heterochromatin formation |
|
| 1452099_at |
Utp25 |
UTP25 small subunit processome component |
1 |
-193104399, -193104402, -193104402, -193115655 |
BG070043 |
215193 |
24 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleus nucleolus nucleolus rRNA processing multicellular organism development rRNA binding protein catabolic process protein destabilization small-subunit processome U3 snoRNA binding U3 snoRNA binding positive regulation of embryonic development embryonic organ development protein localization to nucleolus |
|
| 1434573_at |
Traf3ip3 |
TRAF3 interacting protein 3 |
1 |
-193175503 |
BE986588 |
215243 |
27 |
Golgi membrane cytoplasmic pattern recognition receptor signaling pathway mitochondrion mitochondrial outer membrane lysosome endoplasmic reticulum membrane Golgi apparatus plasma membrane membrane mitochondrial membrane positive regulation of type I interferon production positive regulation of interferon-alpha production positive regulation of interferon-beta production cellular response to interferon-alpha cellular response to interferon-beta regulation of protein homodimerization activity zf-TRAF domain binding molecular adaptor activity antiviral innate immune response |
|
| 1425958_at |
Il36g |
interleukin 36G |
2 |
24186475 |
AY071843 |
215257 |
46 |
cytokine production positive regulation of cytokine production immune system process inflammatory response to antigenic stimulus cytokine activity cytokine activity extracellular region extracellular space extracellular space nucleoplasm cytoplasm cytosol plasma membrane inflammatory response immune response positive regulation of gene expression cytokine-mediated signaling pathway interleukin-6 production positive regulation of interleukin-6 production innate immune response negative regulation of myoblast differentiation cellular response to lipopolysaccharide negative regulation of myoblast fusion |
|
| 1451243_at |
Rnpep |
arginyl aminopeptidase (aminopeptidase B) |
1 |
-135262698 |
BC019200 |
215615 |
22 |
aminopeptidase activity copper ion binding extracellular region extracellular space extracellular space plasma membrane proteolysis proteolysis peptidase activity metallopeptidase activity zinc ion binding external side of plasma membrane protein processing hydrolase activity secretory granule peptide binding negative regulation of blood pressure metal ion binding cobalt ion binding metalloaminopeptidase activity metalloaminopeptidase activity |
|
| 1434404_at |
Miga1 |
mitoguardin 1 |
3 |
-152273459 |
BB375245 |
215708 |
23 |
mitochondrion mitochondrial outer membrane plasma membrane mitochondrial fusion mitochondrial fusion mitochondrial fusion membrane protein homodimerization activity protein heterodimerization activity |
|
| 1426159_x_at |
Tcrb-J |
T cell receptor beta, joining region |
6 |
|
U46841 |
21580 |
50 |
|
|
| 1454658_at |
Ilvbl |
ilvB (bacterial acetolactate synthase)-like |
10 |
78574512, 78574499, 78574990, 78574990 |
BI408416 |
216136 |
19 |
magnesium ion binding fatty acid alpha-oxidation catalytic activity acetolactate synthase activity endoplasmic reticulum endoplasmic reticulum membrane acetolactate synthase complex lipid metabolic process fatty acid metabolic process isoleucine biosynthetic process valine biosynthetic process membrane lyase activity thiamine pyrophosphate binding metal ion binding flavin adenine dinucleotide binding |
|
| 1437377_a_at |
Polrmt |
polymerase (RNA) mitochondrial (DNA directed) |
10 |
-79736124 |
BB739221 |
216151 |
29 |
3'-5'-RNA exonuclease activity DNA-directed RNA polymerase complex mitochondrial promoter sequence-specific DNA binding DNA binding DNA primase activity DNA-directed 5'-3' RNA polymerase activity DNA-directed 5'-3' RNA polymerase activity protein binding mitochondrion mitochondrion mitochondrial matrix DNA-templated transcription mitochondrial transcription mitochondrial transcription transcription initiation at mitochondrial promoter transferase activity nucleotidyltransferase activity protein-containing complex protein-containing complex mitochondrial DNA-directed RNA polymerase complex mitochondrial nucleoid sequence-specific DNA binding sequence-specific DNA binding |
|
| 1455019_x_at |
Ckap4 |
cytoskeleton-associated protein 4 |
10 |
-84526304 |
BB818012 |
216197 |
39 |
molecular_function protein binding cytoplasm endoplasmic reticulum endoplasmic reticulum rough endoplasmic reticulum rough endoplasmic reticulum lipid droplet cytoskeleton plasma membrane biological_process cell surface membrane |
04141 |
| 1434306_at |
Rab3ip |
RAB3A interacting protein |
10 |
-116905779 |
BF319015 |
216363 |
30 |
guanyl-nucleotide exchange factor activity protein binding nucleus cytoplasm centrosome cytosol cytoskeleton protein targeting to membrane exocytosis protein transport small GTPase binding small GTPase binding protein localization to organelle identical protein binding identical protein binding cell projection perinuclear region of cytoplasm GTPase binding negative regulation of filopodium assembly cilium assembly Golgi to plasma membrane transport vesicle proximal dendrite |
|
| 1428332_at |
Pik3ip1 |
phosphoinositide-3-kinase interacting protein 1 |
11 |
3330730 |
AW556858 |
216505 |
28 |
endopeptidase activity signaling receptor binding extracellular space plasma membrane membrane negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction phosphatidylinositol 3-kinase inhibitor activity phosphatidylinositol 3-kinase inhibitor activity |
|
| 1416542_at |
Phf1 |
PHD finger protein 1 |
17 |
26933126 |
NM_009343 |
21652 |
36 |
transcription corepressor binding DNA binding chromatin binding chromatin binding protein binding nucleus nucleus nucleoplasm cytoplasm centrosome cytosol cytoskeleton chromatin organization chromatin organization regulation of DNA-templated transcription DNA damage response methylated histone binding methylated histone binding methylated histone binding ESC/E(Z) complex ESC/E(Z) complex site of double-strand break identical protein binding metal ion binding DNA repair-dependent chromatin remodeling histone methyltransferase binding |
|
| 1434648_a_at |
Ccm2 |
cerebral cavernous malformation 2 |
11 |
6560182, 6546886 |
BI903794 |
216527 |
60 |
blood vessel development vasculogenesis vasculogenesis vasculogenesis in utero embryonic development in utero embryonic development endothelial cell development endothelial cell development vasculature development vasculature development endothelium development protein binding cytoplasm mitochondrion heart development heart development heart development heart development protein-containing complex multicellular organism growth multicellular organism growth cell-cell junction organization regulation of angiogenesis inner ear development venous blood vessel morphogenesis venous blood vessel morphogenesis pericardium development pericardium development blood vessel endothelial cell differentiation endothelial tube morphogenesis |
|
| 1436034_at |
Cep68 |
centrosomal protein 68 |
11 |
-20227036 |
AW550283 |
216543 |
20 |
nucleoplasm cytoplasm centrosome cytosol cytoskeleton centrosome cycle centriole-centriole cohesion protein kinase binding protein domain specific binding cell junction protein localization to organelle centriolar satellite |
|
| 1427241_at |
Papolg |
poly(A) polymerase gamma |
11 |
-23862645 |
BC019635 |
216578 |
16 |
nucleotide binding RNA binding ATP binding nucleus nucleus nucleoplasm cytosol mRNA polyadenylation mRNA processing nuclear body transferase activity nucleotidyltransferase activity RNA 3'-end processing metal ion binding poly(A) RNA polymerase activity |
03015 |
| 1460204_at |
Tec |
tec protein tyrosine kinase |
5 |
-72755717 |
NM_013689 |
21682 |
76 |
nucleotide binding adaptive immune response adaptive immune response immune system process protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding cytoplasm cytosol cytoskeleton plasma membrane plasma membrane cell-cell junction protein phosphorylation protein phosphorylation integrin-mediated signaling pathway lipid binding regulation of platelet activation regulation of platelet activation membrane kinase activity phosphorylation transferase activity intracellular signal transduction tissue regeneration protein self-association metal ion binding T cell receptor signaling pathway B cell receptor signaling pathway B cell receptor signaling pathway |
04380 04660 |
| 1428466_at |
Chd3 |
chromodomain helicase DNA binding protein 3 |
11 |
-69343272 |
AK011183 |
216848 |
37 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin transcription cis-regulatory region binding DNA binding chromatin binding protein binding nucleus nucleus nucleoplasm nucleoplasm nucleolus cytoplasm centrosome chromatin organization chromatin remodeling chromatin remodeling spindle organization centrosome cycle NuRD complex NuRD complex NuRD complex NuRD complex PML body ATP hydrolysis activity ATP hydrolysis activity centriolar satellite histone binding regulation of cell fate specification negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription ATP-dependent chromatin remodeler activity ATP-dependent chromatin remodeler activity regulation of stem cell differentiation |
|
| 1434873_a_at |
Acap1 |
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 |
11 |
-69881566 |
BB115902 |
216859 |
18 |
molecular_function GTPase activator activity cytoplasm endosome lipid metabolic process signal transduction biological_process membrane lipid catabolic process metal ion binding |
04144 |
| 1451601_a_at |
Spns2 |
SPNS lysolipid transporter 2, sphingosine-1-phosphate |
11 |
-72451637, -72451637 |
BC025823 |
216892 |
43 |
B cell homeostasis lymphocyte homeostasis regulation of humoral immune response regulation of humoral immune response sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway endosome plasma membrane sphingolipid metabolic process lipid transport lipid transport sensory perception of sound membrane membrane transmembrane transporter activity T cell homeostasis sphingolipid transporter activity sphingolipid transporter activity sphingolipid transporter activity regulation of eye pigmentation lymph node development transmembrane transport bone development lymphocyte migration regulation of T cell migration |
|
| 1425025_at |
Tmem106a |
transmembrane protein 106A |
11 |
101582241, 101582241, 101582298 |
BC022145 |
217203 |
14 |
immune system process molecular_function plasma membrane membrane positive regulation of interleukin-1 beta production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production CD80 biosynthetic process CD86 biosynthetic process macrophage activation positive regulation of canonical NF-kappaB signal transduction positive regulation of MAPK cascade innate immune response positive regulation of MHC class II biosynthetic process positive regulation of nitric oxide metabolic process |
|
| 1460363_at |
Tnrc6c |
trinucleotide repeat containing 6C |
11 |
117654288 |
BB795102 |
217351 |
25 |
P-body endoderm formation molecular_function nucleic acid binding RNA binding nucleoplasm cytosol regulation of translation transforming growth factor beta receptor signaling pathway endoderm development regulatory ncRNA-mediated gene silencing embryonic hemopoiesis miRNA-mediated post-transcriptional gene silencing miRNA-mediated post-transcriptional gene silencing embryonic organ development positive regulation of nuclear-transcribed mRNA poly(A) tail shortening positive regulation of nuclear-transcribed mRNA poly(A) tail shortening lung saccule development regulation of miRNA-mediated gene silencing positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
|
| 1426640_s_at |
Trib2 |
tribbles pseudokinase 2 |
12 |
-15791726 |
BB354684 |
217410 |
56 |
protein kinase activity protein kinase inhibitor activity ATP binding nucleus cytoplasm cytoskeleton protein phosphorylation mitogen-activated protein kinase kinase binding ubiquitin protein ligase binding positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of interleukin-10 production regulation of MAP kinase activity negative regulation of DNA-binding transcription factor activity negative regulation of fat cell differentiation positive regulation of ubiquitin-protein transferase activity ubiquitin-protein transferase regulator activity RNA polymerase II-specific DNA-binding transcription factor binding |
|
| 1448224_at |
Tfam |
transcription factor A, mitochondrial |
10 |
-71225476 |
NM_009360 |
21780 |
225 |
transcription cis-regulatory region binding mitochondrial promoter sequence-specific DNA binding mitochondrial promoter sequence-specific DNA binding transcription coactivator binding DNA binding chromatin binding nucleus mitochondrion mitochondrion mitochondrion mitochondrial matrix mitochondrial transcription mitochondrial transcription transcription initiation at mitochondrial promoter transcription initiation at mitochondrial promoter heat shock protein binding protein-containing complex mitochondrial respiratory chain complex assembly mitochondrial transcription factor activity mitochondrial nucleoid mitochondrial nucleoid sequence-specific DNA binding positive regulation of DNA-templated transcription |
05016 |
| 1415871_at |
Tgfbi |
transforming growth factor, beta induced |
13 |
56609585 |
NM_009369 |
21810 |
91 |
extracellular matrix structural constituent collagen binding extracellular region basement membrane extracellular space extracellular space extracellular space extracellular space trans-Golgi network cell adhesion cell adhesion extracellular matrix organization extracellular matrix organization extracellular matrix extracellular matrix identical protein binding cell adhesion molecule binding extracellular matrix binding localization collagen-containing extracellular matrix |
|
| 1426397_at |
Tgfbr2 |
transforming growth factor, beta receptor II |
9 |
-116087694 |
BG793483 |
21813 |
626 |
nucleotide binding branching involved in blood vessel morphogenesis vasculogenesis in utero embryonic development epithelial to mesenchymal transition heart looping positive regulation of mesenchymal cell proliferation lens development in camera-type eye positive regulation of tolerance induction to self antigen positive regulation of B cell tolerance induction positive regulation of T cell tolerance induction outflow tract septum morphogenesis membranous septum morphogenesis outflow tract morphogenesis aortic valve morphogenesis atrioventricular valve morphogenesis tricuspid valve morphogenesis cardiac left ventricle morphogenesis endocardial cushion fusion growth plate cartilage development growth plate cartilage chondrocyte growth protein kinase activity protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase activity transforming growth factor beta receptor activity transforming growth factor beta receptor activity transforming growth factor beta receptor activity transforming growth factor beta receptor activity, type II protein binding ATP binding glycosaminoglycan binding extracellular space plasma membrane plasma membrane plasma membrane caveola protein phosphorylation protein phosphorylation receptor-mediated endocytosis apoptotic process transmembrane receptor protein serine/threonine kinase signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway Notch signaling pathway smoothened signaling pathway gastrulation brain development heart development heart development negative regulation of cell population proliferation response to xenobiotic stimulus animal organ morphogenesis external side of plasma membrane external side of plasma membrane cell surface regulation of gene expression positive regulation of epithelial cell migration positive regulation of epithelial to mesenchymal transition membrane kinase activity phosphorylation transferase activity activin receptor activity kinase activator activity cell differentiation lung development mitogen-activated protein kinase kinase kinase binding type I transforming growth factor beta receptor binding type I transforming growth factor beta receptor binding type III transforming growth factor beta receptor binding embryonic hemopoiesis aorta morphogenesis signaling receptor activity regulation of cell population proliferation receptor complex receptor complex membrane raft positive regulation of angiogenesis SMAD binding SMAD binding SMAD binding metal ion binding activin binding positive regulation of smooth muscle cell proliferation embryonic cranial skeleton morphogenesis artery morphogenesis transforming growth factor beta binding transforming growth factor beta binding transforming growth factor beta binding positive regulation of NK T cell differentiation cartilage development roof of mouth development negative regulation of cardiac muscle cell proliferation molecular adaptor activity positive regulation of SMAD protein signal transduction SMAD protein signal transduction ventricular septum morphogenesis lung morphogenesis bronchus development bronchus morphogenesis trachea morphogenesis trachea formation mammary gland morphogenesis lung lobe morphogenesis Langerhans cell differentiation secondary palate development transforming growth factor beta ligand-receptor complex response to cholesterol response to cholesterol cellular response to growth factor stimulus regulation of stem cell proliferation positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation inferior endocardial cushion morphogenesis lens fiber cell apoptotic process miRNA transport positive regulation of reactive oxygen species metabolic process positive regulation of CD4-positive, alpha-beta T cell proliferation regulation of stem cell differentiation |
04010 04060 04144 04350 04380 04520 05142 05200 05210 05212 05220 |
| 1433795_at |
Tgfbr3 |
transforming growth factor, beta receptor III |
5 |
-107106566 |
BM122301 |
21814 |
93 |
blood vessel development vasculogenesis osteoblast differentiation in utero embryonic development blastocyst development epithelial to mesenchymal transition epithelial to mesenchymal transition liver development blood vessel remodeling muscular septum morphogenesis outflow tract morphogenesis ventricular compact myocardium morphogenesis epicardial cell to mesenchymal cell transition transmembrane signaling receptor activity transforming growth factor beta receptor activity transforming growth factor beta receptor activity transforming growth factor beta receptor activity transforming growth factor beta receptor activity type II transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding transforming growth factor beta receptor binding protein binding glycosaminoglycan binding glycosaminoglycan binding extracellular region extracellular space cytoplasm endoplasmic reticulum plasma membrane immune response transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor complex assembly heparin binding cell population proliferation positive regulation of cell population proliferation external side of plasma membrane cell surface positive regulation of gene expression negative regulation of gene expression negative regulation of epithelial cell migration negative regulation of epithelial to mesenchymal transition coreceptor activity membrane cell migration regulation of transforming growth factor beta receptor signaling pathway fibroblast growth factor binding PDZ domain binding negative regulation of cell migration BMP signaling pathway BMP signaling pathway positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of transforming growth factor beta receptor signaling pathway negative regulation of transforming growth factor beta receptor signaling pathway positive regulation of BMP signaling pathway response to follicle-stimulating hormone collagen metabolic process inhibin-betaglycan-ActRII complex response to prostaglandin E response to luteinizing hormone intracellular signal transduction BMP binding negative regulation of canonical NF-kappaB signal transduction receptor complex SMAD binding SMAD binding activin binding transforming growth factor beta binding transforming growth factor beta binding transforming growth factor beta binding negative regulation of epithelial cell proliferation positive regulation of NF-kappaB transcription factor activity ventricular cardiac muscle tissue morphogenesis roof of mouth development cardiac muscle cell proliferation positive regulation of cardiac muscle cell proliferation definitive hemopoiesis cardiac epithelial to mesenchymal transition definitive erythrocyte differentiation heart trabecula formation positive regulation of SMAD protein signal transduction positive regulation of SMAD protein signal transduction negative regulation of SMAD protein signal transduction ventricular septum morphogenesis apoptotic process involved in morphogenesis epicardium-derived cardiac fibroblast cell development coronary vasculature development coronary vasculature morphogenesis vasculogenesis involved in coronary vascular morphogenesis vasculogenesis involved in coronary vascular morphogenesis visceral serous pericardium development heart trabecula morphogenesis secondary palate development protein-containing complex assembly transforming growth factor beta receptor activity, type III positive regulation of cell migration involved in sprouting angiogenesis blood vessel diameter maintenance negative regulation of extracellular matrix assembly negative regulation of apoptotic process involved in morphogenesis |
|
| 1451416_a_at |
Tgm1 |
transglutaminase 1, K polypeptide |
14 |
-55700008, -55700008 |
BC026422 |
21816 |
66 |
protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity adherens junction animal organ morphogenesis positive regulation of keratinocyte proliferation membrane transferase activity acyltransferase activity peptide cross-linking peptide cross-linking protein metabolic process keratinocyte differentiation keratinization identical protein binding positive regulation of cell cycle metal ion binding |
|
| 1433428_x_at |
Tgm2 |
transglutaminase 2, C polypeptide |
2 |
-158116404 |
AW321975 |
21817 |
290 |
nucleotide binding chromatin nucleosome blood vessel remodeling protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity calcium ion binding calcium ion binding GTP binding GTP binding extracellular region nucleus chromosome cytoplasm mitochondrion mitochondrion cytosol cytosol plasma membrane proteolysis G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway peptidase activity transaminase activity gene expression dopamine secretion membrane transferase activity acyltransferase activity hydrolase activity peptide cross-linking peptide cross-linking peptide cross-linking protein deamination protein domain specific binding extracellular matrix extracellular matrix negative regulation of endoplasmic reticulum calcium ion concentration negative regulation of endoplasmic reticulum calcium ion concentration identical protein binding regulation of apoptotic process positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction phospholipase binding apoptotic cell clearance positive regulation of cell adhesion metal ion binding perinuclear region of cytoplasm positive regulation of smooth muscle cell proliferation protein-glutamine glutaminase activity positive regulation of neurogenesis protein homooligomerization positive regulation of mitochondrial calcium ion concentration positive regulation of mitochondrial calcium ion concentration branching involved in salivary gland morphogenesis salivary gland cavitation collagen-containing extracellular matrix cellular response to cocaine histone serotonyltransferase activity histone dopaminyltransferase activity peptide histaminyltransferase activity cellular response to dopamine cellular response to serotonin regulation of apoptotic cell clearance regulation of apoptotic cell clearance |
05016 |
| 1424988_at |
Mylip |
myosin regulatory light chain interacting protein |
13 |
45389741 |
BC010206 |
218203 |
32 |
ubiquitin-protein transferase activity ubiquitin-protein transferase activity ubiquitin-protein transferase activity cytoplasm cytoskeleton plasma membrane ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process nervous system development cytoskeletal protein binding negative regulation of neuron projection development negative regulation of low-density lipoprotein particle clearance membrane protein ubiquitination transferase activity protein destabilization regulation of low-density lipoprotein particle receptor catabolic process cholesterol homeostasis positive regulation of protein catabolic process metal ion binding ubiquitin protein ligase activity ubiquitin protein ligase activity cellular response to low-density lipoprotein particle stimulus |
|
| 1433649_at |
Kdm1b |
lysine (K)-specific demethylase 1B |
13 |
47043498 |
BM243793 |
218214 |
28 |
negative regulation of transcription by RNA polymerase II chromatin nucleosome chromatin binding protein binding nucleus nucleoplasm chromosome chromatin organization multicellular organism development transcription factor binding zinc ion binding zinc ion binding oxidoreductase activity oxidoreductase activity histone H3K4 demethylase activity histone binding epigenetic programing of female pronucleus transcription initiation-coupled chromatin remodeling positive regulation of transcription by RNA polymerase II metal ion binding flavin adenine dinucleotide binding flavin adenine dinucleotide binding genomic imprinting FAD binding FAD-dependent H3K4me/H3K4me3 demethylase activity FAD-dependent H3K4me/H3K4me3 demethylase activity |
|
| 1460302_at |
Thbs1 |
thrombospondin 1 |
2 |
118111875 |
AI385532 |
21825 |
363 |
angiogenesis phosphatidylserine binding negative regulation of endothelial cell proliferation negative regulation of endothelial cell proliferation negative regulation of cell-matrix adhesion fibronectin binding protease binding sprouting angiogenesis negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II negative regulation of dendritic cell antigen processing and presentation outflow tract morphogenesis endocardial cushion development growth plate cartilage development growth plate cartilage development endopeptidase inhibitor activity integrin binding extracellular matrix structural constituent calcium ion binding protein binding extracellular region fibrinogen complex extracellular space extracellular space extracellular space endoplasmic reticulum apoptotic process inflammatory response inflammatory response response to unfolded protein cell adhesion heparin binding positive regulation of cell population proliferation negative regulation of cell population proliferation response to mechanical stimulus response to glucose external side of plasma membrane cell surface positive regulation of endothelial cell migration negative regulation of endothelial cell migration negative regulation of long-chain fatty acid import across plasma membrane negative regulation of nitric oxide mediated signal transduction negative regulation of cGMP-mediated signaling negative regulation of plasminogen activation positive regulation of macrophage chemotaxis positive regulation of fibroblast migration positive regulation of cell-substrate adhesion cell migration negative regulation of angiogenesis negative regulation of angiogenesis negative regulation of angiogenesis negative regulation of angiogenesis sarcoplasmic reticulum fibroblast growth factor binding peptide cross-linking secretory granule low-density lipoprotein particle binding positive regulation of blood coagulation positive regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of transforming growth factor beta receptor signaling pathway extracellular matrix platelet alpha granule response to magnesium ion negative regulation of interleukin-12 production positive regulation of tumor necrosis factor production response to endoplasmic reticulum stress negative regulation of fibroblast growth factor receptor signaling pathway positive regulation of phosphorylation protein homodimerization activity positive regulation of macrophage activation negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process laminin binding positive regulation of MAP kinase activity positive regulation of blood vessel endothelial cell migration negative regulation of blood vessel endothelial cell migration engulfment of apoptotic cell positive regulation of translation positive regulation of angiogenesis behavioral response to pain blood vessel morphogenesis positive regulation of smooth muscle cell proliferation transforming growth factor beta binding extracellular matrix binding positive regulation of chemotaxis response to calcium ion positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of fibrinolysis collagen-containing extracellular matrix collagen-containing extracellular matrix fibrinogen binding collagen V binding monocyte aggregation positive regulation of transforming growth factor beta production cellular response to nitric oxide negative regulation of cell migration involved in sprouting angiogenesis positive regulation of extrinsic apoptotic signaling pathway via death domain receptors negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis negative regulation of sprouting angiogenesis positive regulation of endothelial cell apoptotic process positive regulation of reactive oxygen species metabolic process negative regulation of endothelial cell chemotaxis |
04115 04145 04350 04510 04512 05144 05219 |
| 1451221_at |
Ice1 |
interactor of little elongation complex ELL subunit 1 |
13 |
-70588688 |
BC018507 |
218333 |
19 |
euchromatin nucleus nucleoplasm transcription elongation factor complex Cajal body nuclear body protein-macromolecule adaptor activity positive regulation of protein-containing complex assembly histone locus body snRNA transcription by RNA polymerase II snRNA transcription by RNA polymerase III positive regulation of transcription by RNA polymerase III positive regulation of intracellular protein transport |
|
| 1423135_at |
Thy1 |
thymus cell antigen 1, theta |
9 |
44043383 |
AV028402 |
21838 |
303 |
angiogenesis regulation of cell-matrix adhesion positive regulation of cellular extravasation GTPase activator activity GTPase activator activity integrin binding integrin binding endoplasmic reticulum cytosol plasma membrane cytoskeleton organization integrin-mediated signaling pathway integrin-mediated signaling pathway integrin-mediated signaling pathway cell-cell signaling cell-cell signaling external side of plasma membrane external side of plasma membrane cell surface membrane apical plasma membrane enzyme binding protein kinase binding negative regulation of cell migration dendrite dendrite growth cone axolemma dendrite membrane neuronal cell body membrane heterotypic cell-cell adhesion GPI anchor binding receptor clustering myelin sheath membrane raft membrane raft membrane raft retinal cone cell development focal adhesion assembly negative regulation of axonogenesis T cell receptor signaling pathway negative regulation of T cell receptor signaling pathway positive regulation of T cell activation positive regulation of release of sequestered calcium ion into cytosol positive regulation of focal adhesion assembly positive regulation of focal adhesion assembly positive regulation of focal adhesion assembly negative regulation of neuron projection regeneration negative regulation of neuron projection regeneration side of membrane cell-cell adhesion regulation of Rho-dependent protein serine/threonine kinase activity |
04670 |
| 1416814_at |
Tia1 |
cytotoxic granule-associated RNA binding protein 1 |
6 |
86404218 |
BG518542 |
21841 |
77 |
regulation of alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome negative regulation of cytokine production nucleic acid binding RNA binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol mRNA processing apoptotic process RNA splicing cytoplasmic stress granule cytoplasmic stress granule negative regulation of translation negative regulation of translation stress granule assembly mRNA 3'-UTR AU-rich region binding regulation of mRNA splicing, via spliceosome nuclear stress granule nuclear stress granule protein localization to cytoplasmic stress granule positive regulation of epithelial cell apoptotic process ribonucleoprotein complex |
|
| 1452821_at |
Tial1 |
Tia1 cytotoxic granule-associated RNA binding protein-like 1 |
7 |
-128439776, -128439776 |
AK020218 |
21843 |
55 |
nucleic acid binding DNA binding RNA binding mRNA 3'-UTR binding protein binding nucleus nucleoplasm cytoplasm lysosome cytosol apoptotic process germ cell development negative regulation of cell population proliferation cytoplasmic stress granule cytoplasmic stress granule stem cell division positive regulation of hippo signaling mRNA 3'-UTR AU-rich region binding stem cell proliferation protein-RNA adaptor activity ribonucleoprotein complex positive regulation of miRNA-mediated gene silencing positive regulation of stem cell proliferation |
|
| 1415869_a_at |
Trim28 |
tripartite motif-containing 28 |
7 |
13024151 |
NM_011588 |
21849 |
205 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin euchromatin heterochromatin in utero embryonic development epithelial to mesenchymal transition DNA binding DNA binding chromatin binding chromatin binding transcription coactivator activity transcription corepressor activity protein kinase activity ubiquitin-protein transferase activity protein binding nucleus nucleus nucleoplasm nucleoplasm DNA repair chromatin organization chromatin organization protein phosphorylation embryo implantation zinc ion binding transferase activity protein sumoylation protein sumoylation SUMO transferase activity ubiquitin protein ligase binding protein-containing complex Krueppel-associated box domain binding positive regulation of protein import into nucleus post-fertilization epigenetic regulation of gene expression positive regulation of DNA binding positive regulation of DNA binding suppression of viral release by host innate immune response innate immune response innate immune response innate immune response positive regulation of DNA repair negative regulation of single stranded viral RNA replication via double stranded DNA intermediate negative regulation of single stranded viral RNA replication via double stranded DNA intermediate negative regulation of single stranded viral RNA replication via double stranded DNA intermediate negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription protein autophosphorylation metal ion binding convergent extension involved in axis elongation embryonic placenta morphogenesis ubiquitin protein ligase activity chromo shadow domain binding genomic imprinting positive regulation of DNA methylation-dependent heterochromatin formation positive regulation of DNA methylation-dependent heterochromatin formation RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex negative regulation of DNA demethylation promoter-specific chromatin binding |
|
| 1460227_at |
Timp1 |
tissue inhibitor of metalloproteinase 1 |
X |
20870165 |
BC008107 |
21857 |
283 |
protease binding protease binding connective tissue replacement involved in inflammatory response wound healing enzyme inhibitor activity cytokine activity extracellular region basement membrane basement membrane extracellular space extracellular space extracellular space growth factor activity metalloendopeptidase inhibitor activity metalloendopeptidase inhibitor activity zinc ion binding positive regulation of cell population proliferation response to hormone negative regulation of peptidase activity negative regulation of endopeptidase activity negative regulation of endopeptidase activity peptidase inhibitor activity extracellular matrix extracellular matrix response to cytokine negative regulation of apoptotic process negative regulation of catalytic activity metal ion binding negative regulation of membrane protein ectodomain proteolysis negative regulation of membrane protein ectodomain proteolysis cellular response to UV-A negative regulation of trophoblast cell migration negative regulation of metallopeptidase activity regulation of integrin-mediated signaling pathway |
|
| 1451253_at |
Pxk |
PX domain containing serine/threonine kinase |
14 |
8098210 |
BC016131 |
218699 |
24 |
actin binding protein kinase activity protein binding ATP binding nucleus cytoplasm cytoplasm early endosome late endosome cytosol plasma membrane plasma membrane plasma membrane protein phosphorylation protein targeting to lysosome inflammatory response endosome to lysosome transport membrane negative regulation of ATP-dependent activity negative regulation of ATP-dependent activity protein-containing complex centriolar satellite phosphatidylinositol binding phosphatidylinositol binding negative regulation of monoatomic ion transport negative regulation of monoatomic ion transport early endosome to late endosome transport modulation of chemical synaptic transmission |
|
| 1438673_at |
Slc4a7 |
solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
14 |
14703024, 14718783 |
AW555750 |
218756 |
49 |
solute:inorganic anion antiporter activity protein binding cytoplasm plasma membrane plasma membrane plasma membrane purine nucleotide biosynthetic process pyrimidine nucleotide biosynthetic process monoatomic ion transport sodium ion transport monoatomic anion transport visual perception sensory perception of sound monoatomic anion transmembrane transporter activity sodium:bicarbonate symporter activity sodium:bicarbonate symporter activity sodium:bicarbonate symporter activity symporter activity bicarbonate transport membrane basolateral plasma membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane apical plasma membrane apical plasma membrane cochlear nucleus development cytoplasmic vesicle stereocilium locomotory exploration behavior cell projection retinal cell programmed cell death regulation of intracellular pH regulation of intracellular pH transmembrane transport auditory receptor cell development auditory receptor cell development camera-type eye photoreceptor cell differentiation retina vasculature morphogenesis in camera-type eye cellular response to growth factor stimulus phagosome acidification |
|
| 1437525_a_at |
Polr3a |
polymerase (RNA) III (DNA directed) polypeptide A |
14 |
-24448693 |
BB559175 |
218832 |
19 |
magnesium ion binding RNA polymerase III activity chromatin binding DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm RNA polymerase III complex RNA polymerase III complex cytoplasm zinc ion binding positive regulation of interferon-beta production tRNA transcription by RNA polymerase III innate immune response DNA/RNA hybrid binding |
00230 00240 01100 03020 04623 |
| 1418162_at |
Tlr4 |
toll-like receptor 4 |
4 |
66827550 |
AF185285 |
21898 |
3343 |
lipopolysaccharide binding lipopolysaccharide binding microglial cell activation lipopolysaccharide immune receptor activity lipopolysaccharide immune receptor activity lipopolysaccharide immune receptor activity phagocytic cup activation of innate immune response toll-like receptor signaling pathway wound healing involved in inflammatory response B cell proliferation involved in immune response immune system process nitric oxide production involved in inflammatory response regulation of dendritic cell cytokine production MyD88-dependent toll-like receptor signaling pathway MyD88-dependent toll-like receptor signaling pathway MyD88-dependent toll-like receptor signaling pathway innate immune response-activating signaling pathway transmembrane signaling receptor activity signaling receptor binding protein binding cytoplasm endosome plasma membrane plasma membrane leukotriene metabolic process nitric oxide biosynthetic process phagocytosis inflammatory response inflammatory response immune response response to oxidative stress signal transduction activation of NF-kappaB-inducing kinase activity I-kappaB phosphorylation I-kappaB phosphorylation JNK cascade JNK cascade response to bacterium external side of plasma membrane cell surface endosome membrane gene expression positive regulation of platelet activation positive regulation of gene expression positive regulation of gene expression positive regulation of gene expression macrophage cytokine production macrophage cytokine production astrocyte development microglia differentiation positive regulation of smooth muscle cell migration membrane neurogenesis positive regulation of B cell proliferation lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide response to lipopolysaccharide response to lipopolysaccharide detection of lipopolysaccharide detection of lipopolysaccharide detection of lipopolysaccharide detection of lipopolysaccharide interferon-beta production type II interferon production interleukin-10 production interleukin-6 production interleukin-6 production tumor necrosis factor production tumor necrosis factor production regulation of tumor necrosis factor production negative regulation of type II interferon production negative regulation of interleukin-17 production negative regulation of interleukin-23 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of chemokine production positive regulation of chemokine production positive regulation of interferon-alpha production positive regulation of interferon-beta production positive regulation of interferon-beta production positive regulation of type II interferon production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 production positive regulation of interleukin-1 production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-12 production positive regulation of interleukin-13 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway TRIF-dependent toll-like receptor signaling pathway cellular response to platelet-derived growth factor stimulus signaling receptor activity B cell proliferation macrophage activation macrophage activation macrophage activation defense response to bacterium identical protein binding cell projection positive regulation of macrophage activation positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction receptor complex receptor complex positive regulation of MAP kinase activity phosphatidylinositol 3-kinase binding innate immune response MHC class II biosynthetic process positive regulation of MHC class II biosynthetic process positive regulation of nitric oxide biosynthetic process positive regulation of nitric oxide biosynthetic process response to ethanol mast cell activation positive regulation of transcription by RNA polymerase II positive regulation of JNK cascade positive regulation of JNK cascade lymphocyte proliferation lipopolysaccharide receptor complex protein heterodimerization activity perinuclear region of cytoplasm positive regulation of smooth muscle cell proliferation positive regulation of lymphocyte proliferation regulation of inflammatory response positive regulation of inflammatory response positive regulation of inflammatory response positive regulation of peptidyl-tyrosine phosphorylation defense response to Gram-negative bacterium defense response to Gram-negative bacterium detection of temperature stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of pain positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity stress-activated MAPK cascade positive regulation of nitric-oxide synthase biosynthetic process intestinal epithelial structure maintenance positive regulation of macrophage cytokine production positive regulation of macrophage cytokine production positive regulation of macrophage cytokine production ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade nucleotide-binding oligomerization domain containing 1 signaling pathway positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway nucleotide-binding oligomerization domain containing 2 signaling pathway positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway response to fatty acid cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipoteichoic acid cellular response to type II interferon negative regulation of cold-induced thermogenesis cellular response to oxidised low-density lipoprotein particle stimulus cellular response to oxidised low-density lipoprotein particle stimulus positive regulation of cytokine production involved in inflammatory response positive regulation of cytokine production involved in inflammatory response positive regulation of NLRP3 inflammasome complex assembly positive regulation of non-canonical NF-kappaB signal transduction positive regulation of reactive oxygen species biosynthetic process positive regulation of cellular response to macrophage colony-stimulating factor stimulus positive regulation of matrix metallopeptidase secretion cellular response to amyloid-beta positive regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of extrinsic apoptotic signaling pathway |
04145 04620 05140 05142 05144 05145 05146 05323 |
| 1422754_at |
Tmod1 |
tropomodulin 1 |
4 |
46039221 |
NM_021883 |
21916 |
65 |
actin binding tropomyosin binding tropomyosin binding tropomyosin binding cytoplasm cytoskeleton cytoskeleton striated muscle thin filament striated muscle thin filament actin filament muscle contraction muscle contraction actin filament organization COP9 signalosome adult locomotory behavior membrane myofibril myofibril myofibril sarcomere sarcomere myofibril assembly myofibril assembly cortical cytoskeleton pointed-end actin filament capping lens fiber cell development |
|
| 1438855_x_at |
Tnfaip2 |
tumor necrosis factor, alpha-induced protein 2 |
12 |
111442660 |
BB233088 |
21928 |
30 |
exocyst exocyst SNARE binding angiogenesis exocytosis exocytosis multicellular organism development cell differentiation exocyst localization |
|
| 1460415_a_at |
Cd40 |
CD40 antigen |
2 |
165055635 |
AI385482 |
21939 |
607 |
positive regulation of protein phosphorylation immune system process immunoglobulin production regulation of immunoglobulin production immune response-regulating cell surface receptor signaling pathway immune response-regulating cell surface receptor signaling pathway antigen binding protein binding extracellular region extracellular space plasma membrane intracellular calcium ion homeostasis intracellular calcium ion homeostasis external side of plasma membrane external side of plasma membrane cell surface cell surface membrane B cell mediated immunity enzyme binding protein domain specific binding CD40 signaling pathway CD40 signaling pathway positive regulation of B cell proliferation positive regulation of B cell proliferation ubiquitin protein ligase binding interleukin-12 production positive regulation of interleukin-12 production CD40 receptor complex CD40 receptor complex signaling receptor activity B cell proliferation B cell proliferation B cell activation B cell activation B cell activation positive regulation of tyrosine phosphorylation of STAT protein defense response to protozoan neuronal cell body varicosity intracellular membrane-bounded organelle positive regulation of MAP kinase activity phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of blood vessel endothelial cell migration positive regulation of GTPase activity positive regulation of angiogenesis positive regulation of transcription by RNA polymerase II positive regulation of isotype switching to IgG isotypes regulation of immune response positive regulation of NF-kappaB transcription factor activity defense response to virus positive regulation of protein kinase C signaling positive regulation of endothelial cell apoptotic process |
04060 04514 04620 04672 05144 05145 05310 05320 05322 05330 05340 05416 |
| 1452389_at |
Cd27 |
CD27 antigen |
6 |
-125232621 |
L24495 |
21940 |
112 |
positive regulation of immunoglobulin production transmembrane signaling receptor activity protein binding apoptotic process external side of plasma membrane external side of plasma membrane cell surface membrane positive regulation of type II interferon production B cell proliferation cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process positive regulation of B cell differentiation positive regulation of T cell differentiation positive regulation of JNK cascade negative regulation of T cell apoptotic process extrinsic apoptotic signaling pathway |
04060 |
| 1449184_at |
Pglyrp1 |
peptidoglycan recognition protein 1 |
7 |
18884689 |
NM_009402 |
21946 |
41 |
immune system process cytokine activity extracellular region extracellular space cytoplasm apoptotic process zinc ion binding N-acetylmuramoyl-L-alanine amidase activity peptidoglycan catabolic process response to bacterium peptidoglycan immune receptor activity peptidoglycan immune receptor activity detection of bacterium detection of bacterium Hsp70 protein binding killing of cells of another organism negative regulation of type II interferon production negative regulation of natural killer cell differentiation involved in immune response defense response to bacterium peptidoglycan binding peptidoglycan binding innate immune response receptor ligand activity negative regulation of inflammatory response defense response to Gram-positive bacterium defense response to Gram-positive bacterium biological process involved in interaction with host molecular adaptor activity antimicrobial humoral immune response mediated by antimicrobial peptide |
|
| 1416731_at |
Top2b |
topoisomerase (DNA) II beta |
14 |
16365205 |
BB166592 |
21974 |
72 |
nucleotide binding resolution of meiotic recombination intermediates heterochromatin sister chromatid segregation neuron migration DNA binding chromatin binding DNA topoisomerase activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm cytosol DNA metabolic process DNA topological change axonogenesis isomerase activity B cell differentiation B cell differentiation forebrain development positive regulation of single stranded viral RNA replication via double stranded DNA intermediate metal ion binding |
|
| 1419494_a_at |
Tpd52 |
tumor protein D52 |
3 |
-8926529, -8926529, -8926529 |
BC002036 |
21985 |
32 |
calcium ion binding protein binding cytoplasm cytoplasm endoplasmic reticulum positive regulation of cell population proliferation B cell differentiation identical protein binding protein homodimerization activity protein homodimerization activity synapse synapse synapse perinuclear region of cytoplasm glutamatergic synapse glutamatergic synapse glutamatergic synapse |
|
| 1425028_a_at |
Tpm2 |
tropomyosin 2, beta |
4 |
-43513725 |
BC024358 |
22004 |
71 |
actin binding structural constituent of cytoskeleton protein binding cytoplasm cytoskeleton muscle thin filament tropomyosin actin filament muscle contraction muscle contraction actin filament organization actin cytoskeleton identical protein binding protein homodimerization activity regulation of ATP-dependent activity protein heterodimerization activity actin filament binding actin filament binding |
04260 05410 05414 |
| 1454851_at |
Nr2c2 |
nuclear receptor subfamily 2, group C, member 2 |
6 |
92091417, 92092432 |
AV162817 |
22026 |
113 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nuclear receptor activity protein binding nucleus nucleoplasm regulation of DNA-templated transcription spermatogenesis zinc ion binding cerebellum development cell differentiation cell differentiation lipopolysaccharide-mediated signaling pathway p38MAPK cascade positive regulation of embryonic development positive regulation of embryonic development sequence-specific DNA binding positive regulation of myoblast differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding positive regulation of behavior anatomical structure development meiotic cell cycle sequence-specific double-stranded DNA binding |
|
| 1453181_x_at |
Plscr1 |
phospholipid scramblase 1 |
9 |
92250193 |
BF319989 |
22038 |
43 |
magnesium ion binding DNA-binding transcription activator activity, RNA polymerase II-specific virus receptor activity DNA binding nuclease activity epidermal growth factor receptor binding calcium ion binding protein binding nucleus nucleus nucleoplasm nucleolus cytoplasm Golgi apparatus cytosol cytosol plasma membrane plasma membrane plasma membrane phosphatidylserine biosynthetic process lipid transport acute-phase response immune response zinc ion binding membrane hydrolase activity plasma membrane phospholipid scrambling plasma membrane phospholipid scrambling SH3 domain binding phospholipid scramblase activity phospholipid scramblase activity enzyme binding myeloid cell differentiation negative regulation of protein binding lead ion binding regulation of mast cell activation response to interferon-alpha CD4 receptor binding positive regulation of apoptotic process negative regulation of viral genome replication positive regulation of innate immune response membrane raft mercury ion binding perinuclear region of cytoplasm defense response to virus regulation of Fc receptor mediated stimulatory signaling pathway collagen-containing extracellular matrix phosphatidylserine exposure on apoptotic cell surface phosphatidylserine exposure on apoptotic cell surface phosphatidylserine exposure on apoptotic cell surface cellular response to lipopolysaccharide cellular response to cytokine stimulus intrinsic apoptotic signaling pathway positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage |
|
| 1448361_at |
Ttc3 |
tetratricopeptide repeat domain 3 |
16 |
94370738 |
BB833716 |
22129 |
33 |
ubiquitin-protein transferase activity ubiquitin-protein transferase activity protein binding nucleus nucleoplasm nucleolus cytoplasm vacuole Golgi apparatus cytosol ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process transferase activity negative regulation of axon extension negative regulation of neuron differentiation metal ion binding protein K48-linked ubiquitination |
|
| 1416119_at |
Txn1 |
thioredoxin 1 |
4 |
-57943372 |
NM_011660 |
22166 |
146 |
negative regulation of transcription by RNA polymerase II protein binding extracellular region nucleus nucleus nucleoplasm cytoplasm cytoplasm mitochondrion cytosol cytosol cytosol response to radiation protein-disulfide reductase activity protein-disulfide reductase activity enzyme binding axon dendrite positive regulation of peptidyl-serine phosphorylation protein homodimerization activity neuronal cell body positive regulation of DNA binding cell redox homeostasis cell redox homeostasis negative regulation of protein export from nucleus protein-disulfide reductase (NAD(P)) activity cellular detoxification of hydrogen peroxide response to nitric oxide positive regulation of peptidyl-cysteine S-nitrosylation |
|
| 1450484_a_at |
Cmpk2 |
cytidine/uridine monophosphate kinase 2 |
12 |
26469214 |
AK004595 |
22169 |
20 |
nucleotide binding cytidylate kinase activity cytidylate kinase activity nucleoside diphosphate kinase activity nucleoside diphosphate kinase activity thymidylate kinase activity thymidylate kinase activity ATP binding nucleoplasm cytoplasm mitochondrion mitochondrion pyrimidine nucleotide biosynthetic process dUDP biosynthetic process dUDP biosynthetic process dTDP biosynthetic process dTDP biosynthetic process dTTP biosynthetic process UMP/dUMP kinase activity kinase activity phosphorylation transferase activity UMP kinase activity nucleoside monophosphate phosphorylation nucleoside monophosphate kinase activity cellular response to lipopolysaccharide |
00240 01100 |
| 1448230_at |
Usp10 |
ubiquitin specific peptidase 10 |
8 |
119910359 |
NM_009462 |
22224 |
51 |
p53 binding cysteine-type endopeptidase activity cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity protein binding nucleus nucleus nucleoplasm cytoplasm endosome early endosome early endosome cytosol cytosol DNA repair proteolysis autophagy DNA damage response peptidase activity cysteine-type peptidase activity regulation of autophagy regulation of autophagy protein deubiquitination protein deubiquitination hydrolase activity cytosolic ribosome DNA damage response, signal transduction by p53 class mediator DNA damage response, signal transduction by p53 class mediator protein-containing complex monoubiquitinated protein deubiquitination negative regulation of canonical NF-kappaB signal transduction transmembrane transporter binding intermediate filament cytoskeleton negative regulation of stress granule assembly cellular response to interleukin-1 rescue of stalled ribosome molecular function inhibitor activity |
|
| 1419063_at |
Ugt8a |
UDP galactosyltransferase 8A |
3 |
-125865271 |
NM_011674 |
22239 |
68 |
protein localization to paranode region of axon 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity endoplasmic reticulum endoplasmic reticulum lipid metabolic process sphingolipid metabolic process galactosylceramide biosynthetic process galactosylceramide biosynthetic process cytoskeleton organization ceramide glucosyltransferase activity UDP-glycosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity glycolipid biosynthetic process membrane transferase activity glycosyltransferase activity paranodal junction assembly myelination N-acylsphingosine galactosyltransferase activity neuron projection morphogenesis |
00600 01100 |
| 1448562_at |
Upp1 |
uridine phosphorylase 1 |
11 |
9118007, 9118102, 9118506 |
NM_009477 |
22271 |
47 |
catalytic activity uridine phosphorylase activity uridine phosphorylase activity uridine phosphorylase activity uridine phosphorylase activity nucleoplasm cytoplasm cytosol cytosol uridine catabolic process uridine catabolic process uridine catabolic process pyrimidine nucleotide metabolic process CMP catabolic process dCMP catabolic process thymidine phosphorylase activity nucleoside metabolic process nucleotide catabolic process transferase activity glycosyltransferase activity pentosyltransferase activity identical protein binding UMP salvage UMP catabolic process dTMP catabolic process dUMP catabolic process uridine metabolic process deoxyuridine phosphorylase activity |
00240 00983 01100 |
| 1421863_at |
Vamp1 |
vesicle-associated membrane protein 1 |
6 |
125215580 |
AK018783 |
22317 |
44 |
SNAP receptor activity mitochondrion plasma membrane vesicle fusion cell surface membrane synaptic vesicle priming synaptic vesicle priming vesicle-mediated transport syntaxin binding SNARE complex cytoplasmic vesicle neuromuscular junction neuromuscular junction regulation of synaptic vesicle fusion to presynaptic active zone membrane regulation of synaptic vesicle fusion to presynaptic active zone membrane SNARE complex assembly SNARE complex assembly specific granule membrane neuron projection synapse tertiary granule membrane presynapse glutamatergic synapse glutamatergic synapse |
04130 |
| 1435244_at |
Vav2 |
vav 2 oncogene |
2 |
-27262103 |
BF535947 |
22325 |
109 |
angiogenesis phosphotyrosine residue binding guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding protein binding cytoplasm cytoplasm cytosol plasma membrane small GTPase-mediated signal transduction cell migration cell migration cell projection assembly lamellipodium assembly intracellular signal transduction regulation of GTPase activity regulation of GTPase activity metal ion binding positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
04062 04510 04650 04660 04662 04664 04666 04670 04810 |
| 1451562_at |
Ggact |
gamma-glutamylamine cyclotransferase |
14 |
-122890859 |
BC006662 |
223267 |
12 |
cytosol lyase activity cellular modified amino acid catabolic process gamma-glutamylaminecyclotransferase activity |
|
| 1435375_at |
Otulinl |
OTU deubiquitinase with linear linkage specificity like |
15 |
-27655070 |
BM224662 |
223433 |
16 |
molecular_function nucleus nuclear envelope cytoplasm endoplasmic reticulum biological_process membrane cytoplasmic side of endoplasmic reticulum membrane |
|
| 1455555_at |
Vipr1 |
vasoactive intestinal peptide receptor 1 |
9 |
121642715 |
BF224468 |
22354 |
46 |
transmembrane signaling receptor activity G protein-coupled receptor activity vasoactive intestinal polypeptide receptor activity vasoactive intestinal polypeptide receptor activity plasma membrane plasma membrane signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled peptide receptor activity membrane peptide hormone binding peptide hormone binding receptor complex |
04080 |
| 1422921_at |
Vpreb3 |
V-set pre-B cell surrogate light chain 3 |
10 |
75948299 |
NM_009514 |
22364 |
18 |
immunoglobulin production negative regulation of immunoglobulin production molecular_function extracellular space endoplasmic reticulum immune response |
|
| 1455197_at |
Rnd1 |
Rho family GTPase 1 |
15 |
-98669204 |
BE852181 |
223881 |
19 |
nucleotide binding GTPase activity GTPase activity signaling receptor binding GTP binding GTP binding cytoplasm cytosol cytosol cytoskeleton plasma membrane plasma membrane adherens junction actin filament organization actin filament organization negative regulation of cell adhesion signal transduction small GTPase-mediated signal transduction actin cytoskeleton membrane neuron remodeling cell migration protein kinase binding regulation of actin cytoskeleton organization intracellular membrane-bounded organelle |
04360 |
| 1455337_at |
Fgd4 |
FYVE, RhoGEF and PH domain containing 4 |
16 |
-16416914, -16416914, -16416914 |
BQ175875 |
224014 |
32 |
actin binding guanyl-nucleotide exchange factor activity cytoplasm cytoplasm cytoskeleton cytoskeleton organization regulation of cell shape lamellipodium lamellipodium assembly microspike assembly filopodium cell projection positive regulation of JUN kinase activity positive regulation of JNK cascade filopodium assembly metal ion binding actin filament binding |
|
| 1434513_at |
Atp13a3 |
ATPase type 13A3 |
16 |
-30312423 |
BQ030867 |
224088 |
16 |
nucleotide binding transporter activity ATP binding endosome intracellular calcium ion homeostasis polyamine transmembrane transporter activity ABC-type putrescine transporter activity P-type ion transporter activity membrane ATP hydrolysis activity ATPase-coupled monoatomic cation transmembrane transporter activity ATPase-coupled monoatomic cation transmembrane transporter activity early endosome membrane late endosome membrane late endosome membrane metal ion binding recycling endosome membrane P-type transmembrane transporter activity polyamine transmembrane transport |
|
| 1437223_s_at |
Xbp1 |
X-box binding protein 1 |
11 |
5520640 |
AV051768 |
22433 |
402 |
negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding angiogenesis regulation of cell growth liver development positive regulation of protein phosphorylation endothelial cell proliferation endothelial cell proliferation protease binding glandular epithelial cell maturation positive regulation of immunoglobulin production positive regulation of immunoglobulin production DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity nucleus nucleus nucleus cytoplasm cytoplasm endoplasmic reticulum endoplasmic reticulum membrane cytosol regulation of DNA-templated transcription regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II ubiquitin-dependent protein catabolic process lipid metabolic process autophagy apoptotic process response to unfolded protein multicellular organism development muscle organ development positive regulation of cell population proliferation response to xenobiotic stimulus regulation of autophagy positive regulation of autophagy negative regulation of myotube differentiation protein transport membrane protein kinase binding cell differentiation positive regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway endoplasmic reticulum unfolded protein response endoplasmic reticulum unfolded protein response endoplasmic reticulum unfolded protein response exocrine pancreas development chromatin DNA binding ubiquitin protein ligase binding regulation of protein stability protein destabilization protein destabilization cellular response to nutrient positive regulation of TOR signaling positive regulation of interleukin-6 production cellular response to insulin stimulus cellular response to oxidative stress response to endoplasmic reticulum stress response to endoplasmic reticulum stress intracellular triglyceride homeostasis positive regulation of vascular wound healing cellular response to vascular endothelial growth factor stimulus phosphatidylinositol 3-kinase regulatory subunit binding cellular response to glucose starvation positive regulation of protein import into nucleus cholesterol homeostasis identical protein binding histone deacetylase binding negative regulation of apoptotic process phosphatidylinositol 3-kinase/protein kinase B signal transduction sequence-specific DNA binding sequence-specific DNA binding ubiquitin-like protein ligase binding positive regulation of MHC class II biosynthetic process positive regulation of B cell differentiation positive regulation of T cell differentiation positive regulation of fat cell differentiation positive regulation of angiogenesis positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein heterodimerization activity vascular endothelial growth factor receptor signaling pathway neuron development response to electrical stimulus fatty acid homeostasis sterol homeostasis serotonin secretion, neurotransmission adipose tissue development epithelial cell maturation involved in salivary gland development intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress negative regulation of ERK1 and ERK2 cascade cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to amino acid stimulus cellular response to fructose stimulus cellular response to glucose stimulus cellular response to interleukin-4 cellular response to peptide hormone stimulus cellular response to fluid shear stress cellular response to laminar fluid shear stress RNA polymerase II transcription regulator complex positive regulation of plasma cell differentiation negative regulation of endoplasmic reticulum unfolded protein response positive regulation of endoplasmic reticulum unfolded protein response positive regulation of protein acetylation negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway positive regulation of lactation response to insulin-like growth factor stimulus cellular response to leukemia inhibitory factor sequence-specific double-stranded DNA binding positive regulation of hepatocyte proliferation positive regulation of endothelial cell apoptotic process |
04141 |
| 1451006_at |
Xdh |
xanthine dehydrogenase |
17 |
-73883894 |
AV286265 |
22436 |
95 |
allantoin metabolic process allantoin metabolic process allantoin metabolic process negative regulation of protein phosphorylation negative regulation of endothelial cell proliferation xanthine dehydrogenase activity xanthine dehydrogenase activity xanthine dehydrogenase activity xanthine dehydrogenase activity xanthine oxidase activity xanthine oxidase activity xanthine oxidase activity iron ion binding protein binding extracellular region extracellular space extracellular space cytoplasm peroxisome cytosol cytosol cytosol guanine catabolic process guanine catabolic process inosine catabolic process inosine catabolic process inosine catabolic process deoxyinosine catabolic process deoxyinosine catabolic process deoxyinosine catabolic process adenosine catabolic process adenosine catabolic process adenosine catabolic process deoxyadenosine catabolic process deoxyguanosine catabolic process AMP catabolic process AMP catabolic process IMP catabolic process IMP catabolic process activation of cysteine-type endopeptidase activity involved in apoptotic process lactation hypoxanthine catabolic process hypoxanthine catabolic process hypoxanthine catabolic process xanthine catabolic process xanthine catabolic process xanthine catabolic process response to aluminum ion negative regulation of gene expression iron-sulfur cluster assembly oxidoreductase activity sarcoplasmic reticulum molybdenum ion binding regulation of epithelial cell differentiation identical protein binding protein homodimerization activity molybdopterin cofactor binding amide catabolic process amide catabolic process amide catabolic process negative regulation of endothelial cell differentiation GMP catabolic process dGMP catabolic process dAMP catabolic process metal ion binding nitrite reductase (NO-forming) activity flavin adenine dinucleotide binding iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction hypoxanthine dehydrogenase activity hypoxanthine dehydrogenase activity hypoxanthine dehydrogenase activity hypoxanthine oxidase activity hypoxanthine oxidase activity hypoxanthine oxidase activity FAD binding positive regulation of p38MAPK cascade negative regulation of vascular endothelial growth factor signaling pathway positive regulation of reactive oxygen species metabolic process negative regulation of vasculogenesis |
00230 00232 00983 01100 04146 |
| 1425058_at |
Zfp472 |
zinc finger protein 472 |
17 |
32965830 |
BC023090 |
224691 |
18 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II |
|
| 1439505_at |
Clic5 |
chloride intracellular channel 5 |
17 |
44188571 |
AA210377 |
224796 |
35 |
response to dietary excess diet induced thermogenesis chloride channel activity chloride channel activity cytoplasm cytoplasm mitochondrion Golgi apparatus cytoskeleton plasma membrane plasma membrane monoatomic ion transport chloride transport chloride transport visual perception sensory perception of sound sensory perception of sound protein localization actin cytoskeleton membrane membrane stereocilium stereocilium bundle monoatomic ion transmembrane transport monoatomic ion channel complex chloride channel complex neuromuscular process controlling balance response to stimulus auditory receptor cell stereocilium organization |
|
| 1459805_x_at |
Dus3l |
dihydrouridine synthase 3 like |
17 |
56764750 |
BB482412 |
224907 |
20 |
tRNA dihydrouridine synthesis mRNA processing regulation of translation tRNA processing oxidoreductase activity tRNA dihydrouridine synthase activity tRNA dihydrouridine synthase activity metal ion binding flavin adenine dinucleotide binding tRNA-dihydrouridine47 synthase activity mRNA dihydrouridine synthase activity |
|
| 1424641_a_at |
Thoc1 |
THO complex 1 |
18 |
9958179 |
BC024951 |
225160 |
36 |
transcription export complex THO complex THO complex part of transcription export complex THO complex part of transcription export complex chromosome, telomeric region DNA binding RNA binding protein binding nucleus cytoplasm mRNA processing mRNA export from nucleus mRNA export from nucleus apoptotic process signal transduction RNA splicing nuclear speck regulation of DNA-templated transcription elongation regulation of apoptotic process mRNA transport |
03013 03040 |
| 1428837_at |
Klhl14 |
kelch-like 14 |
18 |
-21550378 |
AK018108 |
225266 |
18 |
protein binding cytoplasm cytoplasm endoplasmic reticulum endoplasmic reticulum cytosol actin cytoskeleton membrane aggresome neuron projection neuron projection neuronal cell body neuronal cell body |
|
| 1451277_at |
Ptgr3 |
prostaglandin reductase 3 |
18 |
84088157 |
BC025897 |
225791 |
18 |
mitochondrion peroxisome lipid metabolic process zinc ion binding oxidoreductase activity 13-prostaglandin reductase activity 13-prostaglandin reductase activity negative regulation of fat cell differentiation 15-oxoprostaglandin 13-oxidase activity |
|
| 1433537_at |
Atrx |
ATRX, chromatin remodeler |
X |
-105797614 |
AV112912 |
22589 |
138 |
nucleotide binding meiotic spindle organization nuclear chromosome condensed chromosome, centromeric region chromosome, telomeric region heterochromatin DNA binding chromatin binding chromatin binding helicase activity protein binding ATP binding nucleus nucleus nucleoplasm chromosome pericentric heterochromatin pericentric heterochromatin DNA repair chromatin organization nucleosome assembly chromatin remodeling chromatin remodeling transcription by RNA polymerase II DNA damage response spermatogenesis positive regulation of nuclear cell cycle DNA replication DNA translocase activity nuclear body PML body hydrolase activity DNA damage response, signal transduction by p53 class mediator forebrain development replication fork processing replication fork processing chromatin DNA binding subtelomeric heterochromatin formation subtelomeric heterochromatin formation positive regulation of telomere maintenance methylated histone binding methylated histone binding post-embryonic forelimb morphogenesis multicellular organism growth histone binding histone binding histone binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding Sertoli cell development chromo shadow domain binding chromosome organization involved in meiotic cell cycle protein localization to chromosome, telomeric region seminiferous tubule development cellular response to hydroxyurea chromosome, subtelomeric region ATP-dependent chromatin remodeler activity negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric |
|
| 1460366_at |
Eml3 |
echinoderm microtubule associated protein like 3 |
19 |
8929693, 8929662 |
BC022146 |
225898 |
16 |
microtubule cytoskeleton organization nucleus cytoplasm spindle cytoskeleton microtubule spindle microtubule cell cycle mitotic metaphase chromosome alignment microtubule binding microtubule cytoskeleton midbody protein self-association cell division mitotic spindle regulation of mitotic spindle assembly mitotic spindle microtubule |
|
| 1434245_a_at |
Cyb561a3 |
cytochrome b561 family, member A3 |
19 |
10577156, 10577447 |
BB218627 |
225912 |
14 |
nucleolus lysosome lysosomal membrane lysosomal membrane endosome intracellular iron ion homeostasis membrane oxidoreductase activity oxidoreductase activity late endosome membrane intracellular membrane-bounded organelle metal ion binding transmembrane ascorbate ferrireductase activity |
|
| 1433771_at |
Abhd17b |
abhydrolase domain containing 17B |
19 |
21653308 |
AV173092 |
226016 |
18 |
protein depalmitoylation protein depalmitoylation protein depalmitoylation endosome plasma membrane plasma membrane proteolysis serine-type peptidase activity palmitoyl-(protein) hydrolase activity palmitoyl-(protein) hydrolase activity palmitoyl-(protein) hydrolase activity endosome membrane postsynaptic density membrane hydrolase activity cell projection synapse postsynaptic membrane recycling endosome membrane postsynaptic density membrane postsynaptic recycling endosome membrane glutamatergic synapse regulation of postsynapse organization regulation of postsynapse organization regulation of protein localization to synapse negative regulation of protein localization to microtubule regulation of dendritic spine maintenance positive regulation of protein localization to endosome |
|
| 1427318_s_at |
Myof |
myoferlin |
19 |
-37899035 |
BI555209 |
226101 |
45 |
plasma membrane repair plasma membrane repair phospholipid binding phospholipid binding phospholipid binding nucleus plasma membrane plasma membrane caveola glycerol metabolic process membrane regulation of vascular endothelial growth factor receptor signaling pathway cytoplasmic vesicle T-tubule organization T-tubule organization centriolar satellite cellular response to heat intracellular membrane-bounded organelle metal ion binding muscle cell development membrane fusion |
|
| 1454708_at |
Ablim1 |
actin-binding LIM protein 1 |
19 |
-57032732, -57032732, -57032732, -57032732, -57032732 |
BG065289 |
226251 |
51 |
stress fiber stress fiber actin binding protein binding cytoplasm cytoskeleton transcription by RNA polymerase II cytoskeleton organization axon guidance postsynaptic density actin cytoskeleton actin cytoskeleton lamellipodium lamellipodium assembly lamellipodium assembly positive regulation of transcription by RNA polymerase II metal ion binding actin filament binding cilium assembly cilium assembly |
04360 |
| 1419922_s_at |
Atrnl1 |
attractin like 1 |
19 |
57611033 |
AW555641 |
226255 |
20 |
Notch binding protein binding plasma membrane G protein-coupled receptor signaling pathway membrane carbohydrate binding |
|
| 1455544_at |
Zranb3 |
zinc finger, RAN-binding domain containing 3 |
1 |
-127954178, -127954178, -127954178 |
BM228797 |
226409 |
21 |
nucleotide binding nucleic acid binding catalytic activity helicase activity nuclease activity endonuclease activity DNA endonuclease activity DNA endonuclease activity ATP binding nucleus nucleoplasm chromosome DNA repair DNA repair DNA damage response metabolic process zinc ion binding response to UV hydrolase activity replication fork processing replication fork processing DNA rewinding ATP-dependent DNA/DNA annealing activity nuclear replication fork nuclear replication fork negative regulation of DNA recombination metal ion binding K63-linked polyubiquitin modification-dependent protein binding replication fork reversal ATP-dependent chromatin remodeler activity |
|
| 1457035_at |
Ifi207 |
interferon activated gene 207 |
1 |
-173723427 |
AI607873 |
226691 |
13 |
negative regulation of transcription by RNA polymerase II activation of innate immune response activation of innate immune response double-stranded DNA binding double-stranded DNA binding nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol cytosol transcription factor binding monocyte differentiation positive regulation of interleukin-1 beta production cellular response to interferon-beta cellular response to glucose starvation identical protein binding negative regulation of DNA binding negative regulation of viral genome replication negative regulation of gene expression, epigenetic negative regulation of innate immune response negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II defense response to virus cellular response to ionizing radiation intrinsic apoptotic signaling pathway by p53 class mediator activation of cysteine-type endopeptidase activity negative regulation of AIM2 inflammasome complex assembly negative regulation of cysteine-type endopeptidase activity |
|
| 1423962_at |
Wdr26 |
WD repeat domain 26 |
1 |
-181173225 |
BC020044 |
226757 |
29 |
ubiquitin ligase complex molecular_function nucleus nucleoplasm cytoplasm mitochondrion cytosol GID complex proteasome-mediated ubiquitin-dependent protein catabolic process |
|
| 1455816_a_at |
Kctd3 |
potassium channel tetramerisation domain containing 3 |
1 |
-188971095, -188971097 |
BB321232 |
226823 |
18 |
molecular_function protein binding plasma membrane biological_process membrane protein homooligomerization |
|
| 1424706_at |
Zfp51 |
zinc finger protein 51 |
17 |
21450373 |
BC011183 |
22709 |
19 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II |
|
| 1425495_at |
Zfp62 |
zinc finger protein 62 |
11 |
49203291, 49203730, 49204318 |
BC022935 |
22720 |
23 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific nucleus nucleus regulation of transcription by RNA polymerase II metal ion binding |
|
| 1433564_at |
Dgkd |
diacylglycerol kinase, delta |
1 |
87853286 |
BB094429 |
227333 |
35 |
nucleotide binding ATP-dependent diacylglycerol kinase activity ATP-dependent diacylglycerol kinase activity ATP-dependent diacylglycerol kinase activity ATP binding cytoplasm cytosol plasma membrane clathrin-coated pit lipid metabolic process phosphatidic acid biosynthetic process endocytosis signal transduction protein kinase C-activating G protein-coupled receptor signaling pathway protein transport membrane kinase activity phosphorylation transferase activity kinase binding cytoplasmic vesicle intracellular signal transduction identical protein binding protein homodimerization activity positive regulation of epidermal growth factor receptor signaling pathway diacylglycerol metabolic process diacylglycerol metabolic process diacylglycerol metabolic process lipid phosphorylation lipid phosphorylation lipid phosphorylation metal ion binding protein heterodimerization activity negative regulation of protein kinase C signaling positive regulation of clathrin-dependent endocytosis |
00561 00564 01100 04070 |
| 1437870_at |
Slco4c1 |
solute carrier organic anion transporter family, member 4C1 |
1 |
-96818783 |
AV024403 |
227394 |
28 |
plasma membrane monoatomic ion transport multicellular organism development spermatogenesis organic anion transmembrane transporter activity sodium-independent organic anion transmembrane transporter activity organic anion transport membrane basolateral plasma membrane basolateral plasma membrane transmembrane transporter activity cell differentiation sodium-independent organic anion transport transmembrane transport |
|
| 1436312_at |
Ikzf1 |
IKAROS family zinc finger 1 |
11 |
11690176, 11685924 |
AV317621 |
22778 |
243 |
negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific natural killer cell differentiation DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex pericentric heterochromatin pericentric heterochromatin cytoplasm cytosol chromatin organization regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cell cycle multicellular organism development poly-pyrimidine tract binding positive regulation of gene expression protein domain specific binding hemopoiesis lymphocyte differentiation B cell differentiation T cell differentiation erythrocyte differentiation forebrain development positive regulation of transcription elongation by RNA polymerase II protein-containing complex protein-DNA complex amacrine cell differentiation positive regulation of multicellular organism growth positive regulation of multicellular organism growth identical protein binding sequence-specific DNA binding establishment of protein localization positive regulation of neutrophil differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of RNA polymerase II transcription preinitiation complex assembly positive regulation of transcription by RNA polymerase II metal ion binding lymph node development thymus development Peyer's patch development gland development retinal bipolar neuron differentiation |
|
| 1436649_at |
Ikzf3 |
IKAROS family zinc finger 3 |
11 |
-98464692 |
BB151746 |
22780 |
57 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol regulation of transcription by RNA polymerase II response to bacterium B cell differentiation T cell differentiation regulation of B cell proliferation B cell activation identical protein binding protein homodimerization activity histone deacetylase binding regulation of apoptotic process sequence-specific DNA binding sequence-specific DNA binding regulation of B cell differentiation regulation of lymphocyte differentiation positive regulation of transcription by RNA polymerase II metal ion binding protein heterodimerization activity promoter-specific chromatin binding |
|
| 1451451_at |
Gca |
grancalcin |
2 |
62664326 |
BC021450 |
227960 |
21 |
calcium ion binding calcium ion binding cytoplasm cytosol cytosol plasma membrane membrane protein homodimerization activity metal ion binding protein heterodimerization activity |
|
| 1451141_at |
Mettl8 |
methyltransferase 8, methylcytidine |
2 |
-70964560, -70964561 |
BC004636 |
228019 |
21 |
histone acetyltransferase activity nucleus cytoplasm mitochondrion skeletal muscle tissue development tRNA processing methyltransferase activity mRNA methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity transferase activity methylation fat cell differentiation tRNA (cytidine-3-)-methyltransferase activity positive regulation of mitochondrial translation mitochondrial tRNA modification mRNA methylation mRNA methylation tRNA C3-cytosine methylation |
|
| 1455080_at |
Ppp1r16b |
protein phosphatase 1, regulatory subunit 16B |
2 |
158667134, 158666732 |
BB375209 |
228852 |
25 |
positive regulation of endothelial cell proliferation enzyme inhibitor activity nucleus cytoplasm plasma membrane membrane nuclear speck myosin phosphatase regulator activity protein phosphatase regulator activity regulation of protein dephosphorylation positive regulation of protein dephosphorylation negative regulation of protein dephosphorylation cell projection perinuclear region of cytoplasm regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction establishment of endothelial barrier establishment of endothelial barrier establishment of endothelial barrier negative regulation of peptidyl-serine dephosphorylation positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis regulation of sprouting angiogenesis |
|
| 1452922_at |
Ppp1r3d |
protein phosphatase 1, regulatory subunit 3D |
2 |
-178411205 |
AK011539 |
228966 |
12 |
protein phosphatase type 1 complex phosphoprotein phosphatase activity regulation of glycogen biosynthetic process regulation of glycogen biosynthetic process regulation of glycogen catabolic process protein phosphatase 1 binding enzyme binding glycogen granule glycogen binding |
04910 |
| 1425062_at |
Fcrl1 |
Fc receptor-like 1 |
3 |
87376386, 87376386 |
BF163263 |
229499 |
18 |
plasma membrane cell surface coreceptor activity membrane B cell activation |
|
| 1455046_a_at |
Pogz |
pogo transposable element with ZNF domain |
3 |
94837436 |
BI250645 |
229584 |
44 |
double-strand break repair via homologous recombination chromatin nucleic acid binding DNA binding nucleus nucleus nucleoplasm chromosome cytoplasm cytosol DNA repair DNA recombination DNA damage response cell cycle mitotic sister chromatid cohesion positive regulation of transcription by RNA polymerase II metal ion binding cell division kinetochore assembly |
|
| 1451932_a_at |
Adamtsl4 |
ADAMTS-like 4 |
3 |
-95676200 |
BC016215 |
229595 |
23 |
protease binding epithelial cell development extracellular region interstitial matrix apoptotic process extracellular matrix organization extracellular matrix organization extracellular matrix identical protein binding positive regulation of apoptotic process pigment cell development |
|
| 1435174_at |
Rsbn1 |
rosbin, round spermatid basic protein 1 |
3 |
103914119 |
AW546080 |
229675 |
23 |
protein binding nucleus nucleus chromatin organization biological_process oxidoreductase activity histone H4K20 demethylase activity metal ion binding dioxygenase activity |
|
| 1452717_at |
Slc25a24 |
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24 |
3 |
109123148 |
BM230959 |
229731 |
25 |
adenine nucleotide transmembrane transporter activity ATP transmembrane transporter activity ATP transmembrane transporter activity calcium ion binding mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial transport antiporter activity ADP transport ATP transport membrane cellular response to oxidative stress metal ion binding adenine nucleotide transport transmembrane transport cellular response to calcium ion ATP:inorganic phosphate antiporter activity ADP:inorganic phosphate antiporter activity mitochondrial ATP transmembrane transport |
|
| 1434380_at |
Gbp7 |
guanylate binding protein 7 |
3 |
142530335 |
BM241271 |
229900 |
19 |
nucleotide binding activation of innate immune response immune system process GTPase activity GTPase activity protein binding GTP binding GTP binding membrane hydrolase activity symbiont-containing vacuole membrane cytoplasmic vesicle cytoplasmic vesicle cellular response to interferon-beta defense response to bacterium defense response to protozoan defense response to protozoan defense response to protozoan adhesion of symbiont to host innate immune response defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to virus cytolysis in another organism cellular response to type II interferon cellular response to type II interferon |
|
| 1437760_at |
Galnt12 |
polypeptide N-acetylgalactosaminyltransferase 12 |
4 |
47091922 |
AV376137 |
230145 |
22 |
molecular_function polypeptide N-acetylgalactosaminyltransferase activity polypeptide N-acetylgalactosaminyltransferase activity Golgi apparatus Golgi apparatus protein O-linked glycosylation biological_process membrane transferase activity glycosyltransferase activity carbohydrate binding metal ion binding |
00512 01100 |
| 1426315_a_at |
Tmem268 |
transmembrane protein 268 |
4 |
63558762, 63560226 |
AV326978 |
230279 |
12 |
molecular_function cellular_component biological_process membrane |
|
| 1433968_a_at |
Megf9 |
multiple EGF-like-domains 9 |
4 |
-70431926 |
BQ174710 |
230316 |
22 |
extracellular matrix structural constituent basement membrane basement membrane axon guidance animal organ morphogenesis tissue development membrane |
|
| 1437395_at |
Tut4 |
terminal uridylyl transferase 4 |
4 |
108460007, 108459409 |
BE370775 |
230594 |
33 |
oocyte maturation cytokine production nucleic acid binding protein binding nucleus nucleolus cytoplasm cytoplasm cytosol cytosol zinc ion binding miRNA metabolic process miRNA metabolic process miRNA catabolic process transferase activity nucleotidyltransferase activity stem cell population maintenance regulatory ncRNA-mediated gene silencing pre-miRNA processing RNA 3'-end processing RNA 3'-end processing regulation of lipopolysaccharide-mediated signaling pathway negative regulation of NF-kappaB transcription factor activity positive regulation of interleukin-6 production miRNA binding cytoplasmic ribonucleoprotein granule metal ion binding RNA uridylyltransferase activity RNA uridylyltransferase activity RNA uridylyltransferase activity RNA uridylyltransferase activity interleukin-6-mediated signaling pathway uridylyltransferase activity uridylyltransferase activity RNA 3' uridylation RNA 3' uridylation RNA 3' uridylation retrotransposon silencing by mRNA destabilization polyuridylation-dependent mRNA catabolic process |
|
| 1440819_s_at |
Szt2 |
SZT2 subunit of KICSTOR complex |
4 |
-118362739 |
BB541793 |
230676 |
28 |
lysosome lysosomal membrane peroxisome peroxisome central nervous system development post-embryonic development membrane corpus callosum morphogenesis response to nutrient levels cellular response to amino acid starvation cellular response to glucose starvation pigmentation protein localization to lysosome GATOR2 complex KICSTOR complex regulation of superoxide dismutase activity negative regulation of TORC1 signaling negative regulation of TORC1 signaling GATOR1 complex |
|
| 1435362_at |
Foxj3 |
forkhead box J3 |
4 |
119539660, 119542335 |
BB026073 |
230700 |
38 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus regulation of DNA-templated transcription regulation of transcription by RNA polymerase II male meiosis I spermatogenesis cell differentiation sequence-specific DNA binding positive regulation of transcription by RNA polymerase II meiotic cell cycle sequence-specific double-stranded DNA binding |
|
| 1435087_at |
Zfp362 |
zinc finger protein 362 |
4 |
-128773084 |
BI409907 |
230761 |
7 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity regulation of transcription by RNA polymerase II |
|
| 1428467_at |
Tardbp |
TAR DNA binding protein |
4 |
-148612381 |
AK004440 |
230908 |
286 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding negative regulation of protein phosphorylation nucleic acid binding DNA binding double-stranded DNA binding RNA binding RNA binding RNA binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleoplasm nucleoplasm perichromatin fibrils cytoplasm mitochondrion mRNA processing lipid binding RNA splicing RNA splicing gene expression regulation of gene expression negative regulation of gene expression nuclear speck regulation of protein stability regulation of protein stability positive regulation of insulin secretion interchromatin granule positive regulation of protein import into nucleus regulation of circadian rhythm identical protein binding regulation of apoptotic process intracellular non-membrane-bounded organelle negative regulation by host of viral transcription rhythmic process regulation of cell cycle 3'-UTR-mediated mRNA destabilization 3'-UTR-mediated mRNA stabilization nuclear inner membrane organization pre-mRNA intronic binding molecular condensate scaffold activity amyloid fibril formation |
|
| 1423919_at |
Haus3 |
HAUS augmin-like complex, subunit 3 |
5 |
-34153896 |
BC027393 |
231123 |
26 |
cytoplasm centrosome centrosome cytoskeleton microtubule cell cycle centrosome cycle centrosome cycle spindle assembly spindle assembly cell division HAUS complex HAUS complex mitotic spindle mitotic spindle microtubule |
|
| 1437184_at |
Guf1 |
GUF1 homolog, GTPase |
5 |
69556923 |
BI789973 |
231279 |
18 |
nucleotide binding GTPase activity GTP binding mitochondrion mitochondrion mitochondrial inner membrane translation membrane hydrolase activity positive regulation of translation mitochondrial ribosome binding |
|
| 1434311_at |
Cnot6l |
CCR4-NOT transcription complex, subunit 6-like |
5 |
-96070332, -96070332, -96070332 |
BB025078 |
231464 |
43 |
nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nuclear-transcribed mRNA poly(A) tail shortening catalytic activity nuclease activity exonuclease activity poly(A)-specific ribonuclease activity poly(A)-specific ribonuclease activity poly(A)-specific ribonuclease activity protein binding nucleus nucleus cytoplasm cytoplasm cytoplasm cytosol cytosol mRNA processing regulation of translation positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cytoplasmic mRNA processing body assembly hydrolase activity CCR4-NOT complex CCR4-NOT complex regulatory ncRNA-mediated gene silencing metal ion binding mRNA destabilization |
03018 |
| 1451335_at |
Plac8 |
placenta-specific 8 |
5 |
-100553725, -100553725 |
AF263458 |
231507 |
39 |
chromatin binding protein binding nucleus transcription by RNA polymerase II transcription by RNA polymerase II positive regulation of cell population proliferation response to cold negative regulation of multicellular organism growth defense response to bacterium negative regulation of apoptotic process negative regulation of apoptotic process positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II brown fat cell differentiation positive regulation of cold-induced thermogenesis |
|
| 1454799_at |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
5 |
100846228 |
AV300264 |
231510 |
22 |
1-acylglycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity protein binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane glycerol-3-phosphate metabolic process lipid metabolic process O-acyltransferase activity phospholipid biosynthetic process membrane transferase activity acyltransferase activity triglyceride biosynthetic process triglyceride biosynthetic process regulation of TOR signaling sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity |
00561 00564 01100 |
| 1455370_at |
A630023P12Rik |
RIKEN cDNA A630023P12 gene |
5 |
110514922 |
AI451630 |
231603 |
10 |
molecular_function cellular_component biological_process |
|
| 1424339_at |
Oasl1 |
2'-5' oligoadenylate synthetase-like 1 |
5 |
114923239 |
AB067533 |
231655 |
28 |
immune system process DNA binding RNA binding double-stranded RNA binding double-stranded RNA binding double-stranded RNA binding nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol cytosol response to virus membrane nucleotidyltransferase activity negative regulation of viral genome replication negative regulation of viral genome replication innate immune response defense response to virus defense response to virus regulation of ribonuclease activity interleukin-27-mediated signaling pathway positive regulation of RIG-I signaling pathway |
|
| 1428346_at |
Trafd1 |
TRAF type zinc finger domain containing 1 |
5 |
-121371724, -121371724 |
AK003586 |
231712 |
21 |
protein binding mitochondrion zinc ion binding negative regulation of innate immune response negative regulation of innate immune response metal ion binding |
|
| 1438675_at |
Sfswap |
splicing factor SWAP |
5 |
129501230, 129501239 |
BB278628 |
231769 |
26 |
alternative mRNA splicing, via spliceosome mRNA 5'-splice site recognition mRNA 5'-splice site recognition RNA binding protein binding nucleus RNA processing mRNA processing RNA splicing negative regulation of mRNA splicing, via spliceosome |
|
| 1427327_at |
Pilra |
paired immunoglobin-like type 2 receptor alpha |
5 |
-137821951 |
BB775785 |
231805 |
28 |
protein binding signal transduction membrane MHC class I protein binding |
|
| 1456762_at |
Gimap6 |
GTPase, IMAP family member 6 |
6 |
-48701582 |
BM237714 |
231931 |
18 |
nucleotide binding molecular_function GTP binding cytoplasm cytosol cytosol biological_process |
|
| 1438630_x_at |
Mat2a |
methionine adenosyltransferase 2A |
6 |
-72432795 |
AV260654 |
232087 |
50 |
nucleotide binding methionine adenosyltransferase activity methionine adenosyltransferase activity methionine adenosyltransferase activity ATP binding cytosol S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process one-carbon metabolic process circadian rhythm response to xenobiotic stimulus response to hormone amino acid binding transferase activity protein hexamerization small molecule binding identical protein binding metal ion binding methionine adenosyltransferase complex methionine adenosyltransferase complex protein heterooligomerization response to cAMP cellular response to leukemia inhibitory factor |
00270 01100 |
| 1451125_at |
Paip2b |
poly(A) binding protein interacting protein 2B |
6 |
-83806058 |
BC017133 |
232164 |
21 |
mRNA regulatory element binding translation repressor activity cytoplasm regulation of translation poly(A) binding negative regulation of translation negative regulation of translation translation repressor activity negative regulation of translational initiation |
|
| 1426988_at |
Klhl42 |
kelch-like 42 |
6 |
147091074 |
BB795533 |
232539 |
16 |
protein polyubiquitination protein polyubiquitination ubiquitin-protein transferase activity cytoplasm cytoskeleton cell cycle Cul3-RING ubiquitin ligase complex Cul3-RING ubiquitin ligase complex regulation of microtubule-based process regulation of microtubule-based process proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process cell division |
|
| 1456777_at |
Mgam |
maltase-glucoamylase |
6 |
40628830, 40628830 |
BB072761 |
232714 |
19 |
maltose catabolic process glucan 1,4-alpha-glucosidase activity alpha-1,4-glucosidase activity alpha-1,4-glucosidase activity alpha-1,4-glucosidase activity amylase activity apical plasma membrane maltose alpha-glucosidase activity alpha-glucosidase activity dextrin catabolic process |
00052 00500 01100 04973 |
| 1425128_at |
B3gnt8 |
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 |
7 |
25627623 |
BC025206 |
232984 |
13 |
Golgi membrane Golgi apparatus protein glycosylation protein O-linked glycosylation membrane protein N-acetylglucosaminyltransferase activity protein N-acetylglucosaminyltransferase activity transferase activity glycosyltransferase activity hexosyltransferase activity poly-N-acetyllactosamine biosynthetic process poly-N-acetyllactosamine biosynthetic process |
|
| 1425380_at |
Rasgrp4 |
RAS guanyl releasing protein 4 |
7 |
29134932 |
AF331457 |
233046 |
24 |
guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity nucleoplasm cytoplasm cytosol plasma membrane plasma membrane small GTPase-mediated signal transduction Ras protein signal transduction cell population proliferation response to extracellular stimulus membrane cell differentiation positive regulation of GTPase activity positive regulation of Ras protein signal transduction metal ion binding |
04010 |
| 1425216_at |
Ffar2 |
free fatty acid receptor 2 |
7 |
-30818356, -30818356, -30818356, -30818356, -30818356 |
AV370830 |
233079 |
103 |
leukocyte chemotaxis involved in inflammatory response immune system process mucosal immune response regulation of acute inflammatory response positive regulation of cytokine production involved in immune response cell surface pattern recognition receptor signaling pathway positive regulation of acute inflammatory response to non-antigenic stimulus G protein-coupled receptor activity G protein-coupled receptor activity G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane inflammatory response signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway lipid binding membrane lipid storage lipid storage positive regulation of insulin secretion positive regulation of chemokine production positive regulation of interleukin-8 production glucose homeostasis glucose homeostasis cell projection fat cell differentiation negative regulation of insulin secretion negative regulation of insulin secretion cellular response to fatty acid cellular response to fatty acid cellular response to fatty acid cellular response to fatty acid regulation of peptide hormone secretion regulation of peptide hormone secretion ligand-gated ion channel signaling pathway |
|
| 1460620_at |
Zfp592 |
zinc finger protein 592 |
7 |
80993683 |
BB668116 |
233410 |
30 |
DNA binding protein binding nucleus PH domain binding insulin receptor substrate binding negative regulation of insulin receptor signaling pathway metal ion binding regulation of peptidyl-tyrosine phosphorylation |
|
| 1452857_at |
Crebzf |
CREB/ATF bZIP transcription factor |
7 |
90442780 |
AW546339 |
233490 |
31 |
DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm mitochondrion regulation of DNA-templated transcription regulation of transcription by RNA polymerase II response to virus regulation of gene expression identical protein binding sequence-specific DNA binding negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-binding transcription factor activity RNA polymerase II transcription regulator complex |
|
| 1455452_x_at |
Kctd14 |
potassium channel tetramerisation domain containing 14 |
7 |
97451333, 97453203 |
AW552116 |
233529 |
14 |
molecular_function cellular_component biological_process |
|
| 1451342_at |
Spon1 |
spondin 1, (f-spondin) extracellular matrix protein |
7 |
113765997 |
BC020531 |
233744 |
54 |
extracellular matrix structural constituent protein binding extracellular region cell adhesion cell adhesion positive regulation of protein processing protein processing extracellular matrix positive regulation of protein binding metal ion binding LBD domain binding collagen-containing extracellular matrix negative regulation of amyloid-beta formation positive regulation of amyloid precursor protein catabolic process |
|
| 1428539_at |
Smg1 |
SMG1 nonsense mediated mRNA decay associated PI3K related kinase |
7 |
-118131311 |
AK011909 |
233789 |
32 |
nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein serine/threonine kinase activity protein serine/threonine kinase activity diacylglycerol-dependent serine/threonine kinase activity ATP binding nucleus nucleus nucleoplasm cytoplasm DNA repair protein phosphorylation DNA damage response kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation regulation of telomere maintenance chromatoid body telomeric DNA binding protein autophosphorylation phosphatidylinositol phosphate biosynthetic process metal ion binding |
03015 |
| 1455141_at |
Tnrc6a |
trinucleotide repeat containing 6a |
7 |
123123884 |
BI080625 |
233833 |
40 |
P-body P-body P-body nucleic acid binding RNA binding nucleoplasm nucleoplasm cytoplasm Golgi apparatus cytosol regulation of translation endoderm development cellular response to starvation RISC complex regulatory ncRNA-mediated gene silencing maintenance of protein location in cell miRNA-mediated post-transcriptional gene silencing miRNA-mediated post-transcriptional gene silencing miRNA-mediated gene silencing by inhibition of translation intracellular membrane-bounded organelle perinuclear region of cytoplasm molecular adaptor activity positive regulation of nuclear-transcribed mRNA poly(A) tail shortening |
|
| 1433598_at |
Arglu1 |
arginine and glutamate rich 1 |
8 |
-8666575 |
BG093966 |
234023 |
20 |
nucleoplasm nucleoplasm mitochondrion mitochondrion cytosol |
|
| 1424599_at |
Fgl1 |
fibrinogen-like protein 1 |
8 |
-41191433 |
BC021946 |
234199 |
28 |
adaptive immune response immune system process signaling receptor binding protein binding extracellular region extracellular region extracellular space cell-matrix adhesion cholesterol metabolic process regulation of glucose metabolic process response to stilbenoid identical protein binding regulation of immune response regulation of immune response negative regulation of T cell activation negative regulation of T cell activation adipose tissue development collagen-containing extracellular matrix platelet aggregation hepatocyte proliferation |
|
| 1451777_at |
Ddx60 |
DExD/H box helicase 60 |
8 |
61928086 |
BC013672 |
234311 |
19 |
double-stranded DNA binding RNA binding double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding protein binding cytoplasm cytoplasm cytoplasm cytosol response to virus intermediate filament cytoskeleton defense response to virus defense response to virus positive regulation of MDA-5 signaling pathway positive regulation of RIG-I signaling pathway |
|
| 1435798_a_at |
Sugp2 |
SURP and G patch domain containing 2 |
8 |
70234204, 70234204 |
BB772209 |
234373 |
27 |
molecular_function nucleic acid binding RNA binding nucleus nucleoplasm nucleoplasm RNA processing mRNA processing biological_process RNA splicing nuclear body |
|
| 1438577_at |
Inpp4b |
inositol polyphosphate-4-phosphatase, type II |
8 |
81342561, 81342561 |
BB376947 |
234515 |
33 |
cytoplasm lipid metabolic process intracellular calcium ion homeostasis lipid binding phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity hydrolase activity phosphatidylinositol bisphosphate phosphatase activity phosphatidylinositol trisphosphate phosphatase activity negative regulation of osteoclast differentiation negative regulation of osteoclast differentiation regulation of nucleocytoplasmic transport regulation of bone remodeling phosphatidylinositol dephosphorylation regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction |
00562 01100 04070 |
| 1424831_at |
Cpne2 |
copine II |
8 |
94533027 |
BC023348 |
234577 |
21 |
calcium-dependent phospholipid binding calcium-dependent phospholipid binding nucleus cytoplasm plasma membrane plasma membrane membrane metal ion binding cellular response to calcium ion cellular response to calcium ion |
|
| 1437709_x_at |
Ttc13 |
tetratricopeptide repeat domain 13 |
8 |
-124671326 |
BB492914 |
234875 |
13 |
molecular_function cellular_component biological_process |
|
| 1435397_at |
Zbtb44 |
zinc finger and BTB domain containing 44 |
9 |
31030643 |
AV146691 |
235132 |
23 |
molecular_function DNA binding nucleus biological_process metal ion binding |
|
| 1426232_at |
Msantd2 |
Myb/SANT-like DNA-binding domain containing 2 |
9 |
37489320 |
BC024479 |
235184 |
19 |
molecular_function cellular_component biological_process |
|
| 1428749_at |
Dmxl2 |
Dmx-like 2 |
9 |
-54365157 |
AK018275 |
235380 |
38 |
vacuolar acidification chemical synaptic transmission spermatogenesis brain development sensory perception of smell synaptic vesicle membrane corpus callosum development small GTPase binding cytoplasmic vesicle glucose homeostasis RAVE complex synapse neuronal dense core vesicle |
|
| 1426556_at |
Zfp280d |
zinc finger protein 280D |
9 |
72274887 |
BG066777 |
235469 |
23 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus regulation of DNA-templated transcription metal ion binding |
|
| 1436033_at |
Atosa |
atos homolog A |
9 |
74952879, 74976110, 74953052 |
BG276629 |
235493 |
16 |
molecular_function cellular_component nucleus biological_process |
|
| 1456735_x_at |
Pxylp1 |
2-phosphoxylose phosphatase 1 |
9 |
-96823342 |
BB458645 |
235534 |
18 |
Golgi apparatus Golgi apparatus glycosaminoglycan biosynthetic process glycosaminoglycan biosynthetic process positive regulation of heparan sulfate proteoglycan biosynthetic process membrane dephosphorylation hydrolase activity phosphatase activity phosphatase activity chondroitin sulfate proteoglycan biosynthetic process chondroitin sulfate proteoglycan biosynthetic process |
|
| 1433520_at |
Scap |
SREBF chaperone |
9 |
110333355, 110333287 |
BI412871 |
235623 |
80 |
Golgi membrane response to hypoxia protein binding endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane Golgi apparatus lipid metabolic process immune response steroid metabolic process cholesterol metabolic process lipid binding cholesterol binding membrane regulation of fatty acid metabolic process cytoplasmic vesicle response to insulin SREBP signaling pathway sterol binding SREBP-SCAP complex protein-containing complex regulation of fatty acid biosynthetic process cellular lipid metabolic process protein-containing complex binding regulation of cholesterol biosynthetic process regulation of cholesterol biosynthetic process positive regulation of cholesterol biosynthetic process |
|
| 1433769_at |
Als2cl |
ALS2 C-terminal like |
9 |
110880173, 110880321 |
BM201174 |
235633 |
20 |
GTPase activator activity protein binding cytoplasm cytoplasm endosome organization protein localization endosomal transport small GTPase binding small GTPase binding cytoplasmic vesicle cytoplasmic vesicle identical protein binding regulation of GTPase activity |
|
| 1434331_at |
Ago1 |
argonaute RISC catalytic subunit 1 |
4 |
-126435012, -126435012 |
BG072783 |
236511 |
58 |
P-body nuclear-transcribed mRNA catabolic process transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II complex binding core promoter sequence-specific DNA binding nucleic acid binding RNA binding RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding protein binding nucleus nucleus cytoplasm cytoplasm cytosol cytosol regulation of translation RNA secondary structure unwinding miRNA metabolic process positive regulation of gene expression RISC complex RISC complex RISC complex negative regulation of angiogenesis regulatory ncRNA-mediated gene silencing pre-miRNA processing pre-miRNA processing regulatory ncRNA-mediated post-transcriptional gene silencing miRNA processing miRNA binding miRNA binding miRNA binding miRNA-mediated gene silencing by inhibition of translation cytoplasmic ribonucleoprotein granule cytoplasmic ribonucleoprotein granule positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II RISC-loading complex RISC complex assembly positive regulation of non-canonical NF-kappaB signal transduction ribonucleoprotein complex |
|
| 1454714_x_at |
Phgdh |
3-phosphoglycerate dehydrogenase |
3 |
-98313170 |
AA561726 |
236539 |
78 |
phosphoglycerate dehydrogenase activity phosphoglycerate dehydrogenase activity phosphoglycerate dehydrogenase activity glutamine metabolic process glycine metabolic process L-serine metabolic process L-serine biosynthetic process threonine metabolic process amino acid biosynthetic process gamma-aminobutyric acid metabolic process regulation of gene expression oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor taurine metabolic process spinal cord development glial cell development neural tube development neurogenesis neuron projection development myelin sheath NAD binding G1 to G0 transition |
00260 01100 |
| 1454897_at |
Slc9a7 |
solute carrier family 9 (sodium/hydrogen exchanger), member 7 |
X |
-20098850 |
AV330057 |
236727 |
17 |
endosome Golgi apparatus trans-Golgi network plasma membrane plasma membrane monoatomic ion transport monoatomic cation transport potassium ion transport sodium ion transport regulation of pH antiporter activity sodium:proton antiporter activity sodium:proton antiporter activity potassium:proton antiporter activity potassium:proton antiporter activity membrane intracellular membrane-bounded organelle regulation of intracellular pH recycling endosome recycling endosome membrane transmembrane transport potassium ion transmembrane transport sodium ion import across plasma membrane proton transmembrane transport regulation of Golgi lumen acidification |
|
| 1454882_at |
L3mbtl3 |
L3MBTL3 histone methyl-lysine binding protein |
10 |
-26274467, -26274467 |
BB022070 |
237339 |
23 |
chromatin binding chromatin binding protein binding nucleus nucleus nucleus nucleoplasm nucleolus chromatin organization regulation of DNA-templated transcription zinc ion binding myeloid cell differentiation myeloid cell differentiation macrophage differentiation granulocyte differentiation histone binding identical protein binding erythrocyte maturation negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription metal ion binding regulation of DNA methylation-dependent heterochromatin formation methylation-dependent protein binding regulation of ubiquitin-dependent protein catabolic process positive regulation of ubiquitin-dependent protein catabolic process |
|
| 1444107_at |
Mideas |
mitotic deacetylase associated SANT domain protein |
12 |
-84149173, -84149173 |
BB091357 |
238317 |
21 |
histone deacetylase complex transcription corepressor activity nucleoplasm transcription regulator complex regulation of transcription by RNA polymerase II negative regulation of DNA-templated transcription |
|
| 1421366_at |
Clec5a |
C-type lectin domain family 5, member a |
6 |
-40574897 |
NM_021364 |
23845 |
31 |
virus receptor activity virus receptor activity virus receptor activity positive regulation of cytokine production osteoblast development immune system process protein binding cytosol plasma membrane cell surface membrane myeloid cell differentiation carbohydrate binding negative regulation of myeloid cell apoptotic process negative regulation of apoptotic process innate immune response innate immune response innate immune response |
|
| 1455945_at |
Zfp58 |
zinc finger protein 58 |
13 |
-67490166 |
AV282347 |
238693 |
16 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus nucleus regulation of DNA-templated transcription regulation of transcription by RNA polymerase II metal ion binding |
|
| 1452163_at |
Ets1 |
E26 avian leukemia oncogene 1, 5' domain |
9 |
32696036, 32636240 |
BB151715 |
23871 |
259 |
transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription corepressor binding DNA-binding transcription activator activity, RNA polymerase II-specific immune system process nucleic acid binding nucleic acid binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II positive regulation of cell population proliferation positive regulation of endothelial cell migration positive regulation of gene expression regulation of extracellular matrix disassembly cell differentiation positive regulation of cell migration nuclear receptor coactivator activity PML body organization histone acetyltransferase binding identical protein binding regulation of apoptotic process positive regulation of blood vessel endothelial cell migration sequence-specific DNA binding sequence-specific DNA binding positive regulation of erythrocyte differentiation regulation of angiogenesis positive regulation of angiogenesis negative regulation of cell cycle positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II response to antibiotic cell motility negative regulation of inflammatory response positive regulation of inflammatory response RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription factor binding positive regulation of miRNA transcription positive regulation of leukocyte adhesion to vascular endothelial cell sequence-specific double-stranded DNA binding |
04320 05211 |
| 1430986_at |
Farsb |
phenylalanyl-tRNA synthetase, beta subunit |
1 |
-78424744, -78417957 |
AK012154 |
23874 |
35 |
nucleotide binding magnesium ion binding RNA binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity phenylalanine-tRNA ligase activity ATP binding cytoplasm translation phenylalanyl-tRNA aminoacylation phenylalanyl-tRNA aminoacylation phenylalanine-tRNA ligase complex phenylalanine-tRNA ligase complex ligase activity metal ion binding protein heterotetramerization |
00970 |
| 1453851_a_at |
Gadd45g |
growth arrest and DNA-damage-inducible 45 gamma |
13 |
51846674 |
AK007410 |
23882 |
77 |
protein binding nucleus nucleus nucleus cytoplasm cytoplasm negative regulation of protein kinase activity apoptotic process multicellular organism development cell differentiation type II interferon production identical protein binding positive regulation of apoptotic process positive regulation of MAPK cascade T-helper 1 cell differentiation positive regulation of JNK cascade regulation of cell cycle regulation of cell cycle positive regulation of cold-induced thermogenesis positive regulation of p38MAPK cascade |
04010 04110 04115 |
| 1418216_at |
Ggt5 |
gamma-glutamyltransferase 5 |
10 |
75589380 |
NM_011820 |
23887 |
23 |
peptidyltransferase activity leukotriene-C(4) hydrolase leukotriene-C(4) hydrolase leukotriene-C(4) hydrolase plasma membrane plasma membrane plasma membrane proteolysis amino acid metabolic process fatty acid metabolic process glutathione biosynthetic process glutathione catabolic process glutathione catabolic process inflammatory response inflammatory response peptidase activity membrane transferase activity acyltransferase activity hydrolase activity leukotriene biosynthetic process glutathione hydrolase activity glutathione hydrolase activity leukotriene C4 gamma-glutamyl transferase activity leukotriene D4 biosynthetic process leukotriene D4 biosynthetic process leukotriene D4 biosynthetic process leukotriene D4 biosynthetic process |
00430 00460 00480 00590 01100 |
| 1436395_at |
Card6 |
caspase recruitment domain family, member 6 |
15 |
-5097438 |
BB766747 |
239319 |
18 |
molecular_function cytoplasm regulation of canonical NF-kappaB signal transduction |
04621 |
| 1457264_at |
Phf20l1 |
PHD finger protein 20-like 1 |
15 |
66577571 |
AV349060 |
239510 |
21 |
molecular_function nucleus regulation of DNA-templated transcription regulation of transcription by RNA polymerase II negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of protein catabolic process NSL complex metal ion binding methylation-dependent protein binding |
|
| 1453196_a_at |
Oasl2 |
2'-5' oligoadenylate synthetase-like 2 |
5 |
114896933 |
BQ033138 |
23962 |
26 |
nucleotide binding 2'-5'-oligoadenylate synthetase activity 2'-5'-oligoadenylate synthetase activity immune system process RNA binding double-stranded RNA binding double-stranded RNA binding ATP binding nucleoplasm cytosol purine nucleotide biosynthetic process response to virus membrane transferase activity nucleotidyltransferase activity negative regulation of viral genome replication innate immune response metal ion binding defense response to virus defense response to virus regulation of ribonuclease activity interleukin-27-mediated signaling pathway |
|
| 1436608_at |
Pced1b |
PC-esterase domain containing 1B |
15 |
97247106 |
BB457436 |
239647 |
13 |
molecular_function cellular_component biological_process |
|
| 1449380_at |
Pacsin1 |
protein kinase C and casein kinase substrate in neurons 1 |
17 |
27685238, 27655590 |
BI731319 |
23969 |
49 |
protein binding phospholipid binding phospholipid binding phospholipid binding cytoplasm cytoplasm cytoplasm endosome plasma membrane plasma membrane endocytosis cytoskeleton organization cytoskeleton organization actin filament organization signal transduction cytoskeletal protein binding lipid binding membrane regulation of endocytosis COPI-coated vesicle cytoplasmic vesicle ruffle membrane identical protein binding cell projection neuron projection myelin sheath axon terminus synapse synapse negative regulation of endocytosis perinuclear region of cytoplasm synaptic vesicle endocytosis synaptic vesicle endocytosis neuron development neuron projection morphogenesis neuron projection morphogenesis protein localization to membrane protein localization to plasma membrane plasma membrane tubulation plasma membrane tubulation plasma membrane tubulation photoreceptor ribbon synapse presynapse presynaptic endocytic zone postsynaptic density membrane glutamatergic synapse regulation of postsynaptic neurotransmitter receptor internalization positive regulation of dendrite development positive regulation of dendrite development |
|
| 1434510_at |
Papss2 |
3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
19 |
32620004, 32595714 |
BF780807 |
23972 |
67 |
sulfate assimilation sulfate assimilation sulfate assimilation nucleotide binding catalytic activity adenylylsulfate kinase activity adenylylsulfate kinase activity adenylylsulfate kinase activity sulfate adenylyltransferase (ATP) activity sulfate adenylyltransferase (ATP) activity ATP binding cytosol blood coagulation metabolic process kinase activity phosphorylation transferase activity nucleotidyltransferase activity hormone metabolic process 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process bone development |
00230 00450 00920 01100 |
| 1440226_at |
Zfp760 |
zinc finger protein 760 |
17 |
21707740 |
BB088782 |
240034 |
14 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II |
|
| 1424672_at |
Dmxl1 |
Dmx-like 1 |
18 |
49832996 |
BC020141 |
240283 |
20 |
molecular_function vacuolar acidification RAVE complex |
|
| 1439831_at |
Iigp1c |
interferon inducible GTPase 1C |
18 |
60212076 |
AW111920 |
240327 |
13 |
GTPase activity endoplasmic reticulum membrane defense response cellular response to interferon-beta cellular response to interferon-beta |
|
| 1456126_at |
Malt1 |
MALT1 paracaspase |
18 |
65430989 |
BB485735 |
240354 |
110 |
fibrillar center B-1 B cell differentiation protease binding polkadots immune system process positive regulation of T cell cytokine production endopeptidase activity cysteine-type endopeptidase activity ubiquitin-protein transferase activity protein binding nucleus cytoplasm cytosol cytosol cytosol proteolysis proteolysis apoptotic process canonical NF-kappaB signal transduction activation of NF-kappaB-inducing kinase activity peptidase activity response to fungus hydrolase activity kinase activator activity lipopolysaccharide-mediated signaling pathway CBM complex positive regulation of interleukin-1 beta production positive regulation of interleukin-2 production protein-containing complex small molecule binding T cell proliferation B cell activation B cell activation identical protein binding regulation of apoptotic process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process protein self-association innate immune response innate immune response T cell receptor signaling pathway T cell receptor signaling pathway T cell receptor signaling pathway regulation of T cell receptor signaling pathway positive regulation of T cell activation positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity nuclear export proteolysis involved in protein catabolic process cellular response to lipopolysaccharide positive regulation of T-helper 17 cell differentiation |
04660 04662 |
| 1421923_at |
Sh3bp5 |
SH3-domain binding protein 5 (BTK-associated) |
14 |
-31372613, -31372613 |
BQ179335 |
24056 |
30 |
protein kinase inhibitor activity protein kinase inhibitor activity guanyl-nucleotide exchange factor activity nucleoplasm cytoplasm cytoplasm mitochondrion negative regulation of protein kinase activity membrane nuclear body SH3 domain binding cytoplasmic vesicle membrane cytoplasmic vesicle intracellular signal transduction intracellular signal transduction |
|
| 1449163_at |
Sigirr |
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
7 |
-141091174 |
NM_023059 |
24058 |
68 |
negative regulation of cytokine-mediated signaling pathway acute-phase response signal transduction membrane negative regulation of chemokine production negative regulation of DNA-binding transcription factor activity |
|
| 1450024_at |
Sufu |
SUFU negative regulator of hedgehog signaling |
19 |
46396895 |
AJ308624 |
24069 |
125 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II neural tube closure heart looping ventricular septum development protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm cytoplasm cytosol cilium regulation of DNA-templated transcription smoothened signaling pathway multicellular organism development determination of left/right symmetry beta-catenin binding transcription factor binding transcription factor binding protein kinase binding spinal cord dorsal/ventral patterning smoothened signaling pathway involved in ventral spinal cord interneuron specification smoothened signaling pathway involved in spinal cord motor neuron cell fate specification aorta development cytoplasmic sequestering of transcription factor cytoplasmic sequestering of transcription factor skin development negative regulation of smoothened signaling pathway negative regulation of smoothened signaling pathway coronary vasculature development GLI-SUFU complex negative regulation of ubiquitin-dependent protein catabolic process |
04340 05200 05217 |
| 1438687_at |
Lax1 |
lymphocyte transmembrane adaptor 1 |
1 |
-133679028, -133679028 |
BE630983 |
240754 |
17 |
adaptive immune response immune system process immunoglobulin production Golgi apparatus cytosol plasma membrane plasma membrane immune response immune response membrane protein kinase binding intracellular signal transduction intracellular signal transduction B cell activation SH2 domain binding negative regulation of MAP kinase activity lymphocyte activation lymphocyte activation antigen receptor-mediated signaling pathway antigen receptor-mediated signaling pathway negative regulation of T cell activation negative regulation of T cell activation regulation of lymphocyte activation |
|
| 1419132_at |
Tlr2 |
toll-like receptor 2 |
3 |
-83836271 |
NM_011905 |
24088 |
1959 |
lipopolysaccharide binding amyloid-beta binding amyloid-beta binding microglial cell activation positive regulation of cytokine production toll-like receptor signaling pathway toll-like receptor signaling pathway response to molecule of fungal origin immune system process positive regulation of leukocyte migration regulation of dendritic cell cytokine production cell surface pattern recognition receptor signaling pathway MyD88-dependent toll-like receptor signaling pathway transmembrane signaling receptor activity protein binding cytoplasm Golgi apparatus plasma membrane plasma membrane leukotriene metabolic process nitric oxide biosynthetic process defense response inflammatory response inflammatory response immune response signal transduction I-kappaB phosphorylation learning negative regulation of cell population proliferation response to bacterium external side of plasma membrane cell surface positive regulation of gene expression macrophage cytokine production macrophage cytokine production microglia development membrane positive regulation of Wnt signaling pathway negative regulation of actin filament polymerization cytoplasmic vesicle central nervous system myelin formation response to bacterial lipoprotein response to peptidoglycan chemokine production interleukin-17 production interleukin-6 production interleukin-6 production tumor necrosis factor production negative regulation of interleukin-12 production negative regulation of interleukin-17 production positive regulation of chemokine production positive regulation of chemokine production positive regulation of interferon-beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-18 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production toll-like receptor 2 signaling pathway Toll-like receptor binding Toll-like receptor 1-Toll-like receptor 2 protein complex Toll-like receptor 2-Toll-like receptor 6 protein complex Toll-like receptor 2-Toll-like receptor 6 protein complex signaling receptor activity toll-like receptor TLR6:TLR2 signaling pathway pattern recognition receptor activity pattern recognition receptor activity detection of triacyl bacterial lipopeptide detection of diacyl bacterial lipopeptide triacyl lipopeptide binding triacyl lipopeptide binding triacyl lipopeptide binding diacyl lipopeptide binding identical protein binding peptidoglycan binding cell projection receptor complex cell body protein-containing complex binding protein-containing complex binding innate immune response membrane raft positive regulation of nitric oxide biosynthetic process positive regulation of transcription by RNA polymerase II nitric oxide metabolic process positive regulation of oligodendrocyte differentiation positive regulation of inflammatory response positive regulation of inflammatory response negative regulation of phagocytosis negative regulation of phagocytosis defense response to Gram-positive bacterium defense response to Gram-positive bacterium leukocyte migration positive regulation of NF-kappaB transcription factor activity positive regulation of nitric-oxide synthase biosynthetic process negative regulation of synapse assembly positive regulation of macrophage cytokine production positive regulation of macrophage cytokine production ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade response to fatty acid lipoteichoic acid binding cellular response to bacterial lipopeptide cellular response to bacterial lipopeptide cellular response to lipoteichoic acid cellular response to lipoteichoic acid cellular response to peptidoglycan cellular response to type II interferon lipopeptide binding cellular response to diacyl bacterial lipopeptide cellular response to triacyl bacterial lipopeptide xenophagy positive regulation of non-canonical NF-kappaB signal transduction positive regulation of intracellular signal transduction positive regulation of neutrophil migration positive regulation of cellular response to macrophage colony-stimulating factor stimulus positive regulation of xenophagy positive regulation of matrix metallopeptidase secretion neutrophil migration |
04145 04620 05140 05142 05144 05145 05146 05323 |
| 1452960_at |
Scyl3 |
SCY1-like 3 (S. cerevisiae) |
1 |
163929764, 163929099 |
BB274851 |
240880 |
17 |
Golgi membrane protein kinase activity protein binding ATP binding cytoplasm endoplasmic reticulum Golgi apparatus Golgi apparatus cytosol protein phosphorylation inflammatory response protein localization spinal cord motor neuron differentiation lamellipodium identical protein binding cell projection neuron development |
|
| 1436317_at |
Pgap1 |
post-GPI attachment to proteins 1 |
1 |
-54472999 |
BM115569 |
241062 |
27 |
endoplasmic reticulum endoplasmic reticulum GPI anchor metabolic process GPI anchor biosynthetic process endoplasmic reticulum to Golgi vesicle-mediated transport sensory perception of sound embryonic pattern specification embryonic pattern specification anterior/posterior axis specification anterior/posterior axis specification protein transport membrane hydrolase activity hydrolase activity, acting on ester bonds forebrain regionalization forebrain regionalization phosphatidylinositol deacylase activity phosphatidylinositol deacylase activity head development head development positive regulation of ER to Golgi vesicle-mediated transport |
00563 01100 |
| 1418191_at |
Usp18 |
ubiquitin specific peptidase 18 |
6 |
121245905 |
NM_011909 |
24110 |
78 |
cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity protein binding nucleus nucleus cytosol cytosol proteolysis peptidase activity cysteine-type peptidase activity response to bacterium protein deubiquitination protein deubiquitination hydrolase activity ISG15-specific peptidase activity ISG15-specific peptidase activity response to stilbenoid intracellular membrane-bounded organelle molecular adaptor activity |
|
| 1456147_at |
St8sia6 |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 |
2 |
-13654935 |
BB486599 |
241230 |
22 |
ganglioside biosynthetic process blastocyst hatching alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Golgi apparatus protein glycosylation protein glycosylation N-glycan processing protein O-linked glycosylation lipid metabolic process sialyltransferase activity glycoprotein metabolic process glycolipid biosynthetic process oligosaccharide metabolic process oligosaccharide metabolic process membrane carbohydrate biosynthetic process transferase activity glycosyltransferase activity |
|
| 1450777_at |
Xrn2 |
5'-3' exoribonuclease 2 |
2 |
147012998 |
NM_011917 |
24128 |
37 |
3'-5'-RNA exonuclease activity nuclear-transcribed mRNA catabolic process transcription termination site sequence-specific DNA binding nucleic acid binding DNA binding RNA binding nuclease activity exonuclease activity 5'-3' RNA exonuclease activity 5'-3' RNA exonuclease activity protein binding nucleus nucleus nucleoplasm nucleolus nucleobase-containing compound metabolic process DNA repair DNA recombination DNA-templated transcription termination termination of RNA polymerase II transcription mRNA processing microtubule-based process spermatogenesis 5'-3' exonuclease activity RNA metabolic process aggresome hydrolase activity identical protein binding metal ion binding |
03008 03018 |
| 1433657_at |
Fam78a |
family with sequence similarity 78, member A |
2 |
-32050054, -32050054, -32050054, -32066884 |
BI111848 |
241303 |
11 |
molecular_function cellular_component biological_process |
|
| 1449414_at |
Zfp53 |
zinc finger protein 53 |
17 |
21488987 |
NM_013843 |
24132 |
19 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific protein binding nucleus regulation of transcription by RNA polymerase II |
|
| 1448760_at |
Zfp68 |
zinc finger protein 68 |
5 |
-138603651 |
NM_013844 |
24135 |
29 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II |
|
| 1434418_at |
Cers6 |
ceramide synthase 6 |
2 |
68861440 |
BQ176664 |
241447 |
43 |
DNA binding protein binding endoplasmic reticulum lipid metabolic process inflammatory response membrane transferase activity sphingolipid biosynthetic process ceramide biosynthetic process ceramide biosynthetic process ceramide biosynthetic process ceramide biosynthetic process sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity positive regulation of oligodendrocyte apoptotic process |
|
| 1447788_s_at |
Tspyl3 |
TSPY-like 3 |
2 |
-153222369 |
BB308532 |
241732 |
10 |
chromatin molecular_function chromatin binding nucleus biological_process histone binding |
|
| 1456328_at |
Bank1 |
B cell scaffold protein with ankyrin repeats 1 |
3 |
-136053363 |
AI451642 |
242248 |
24 |
MAPK cascade protease binding signaling receptor binding signaling receptor binding protein binding signal transduction response to bacterium interleukin-6 production negative regulation of interleukin-6 production signaling adaptor activity B cell activation B cell activation phospholipase binding positive regulation of MAPK cascade phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of translational initiation perinuclear region of cytoplasm positive regulation of peptidyl-tyrosine phosphorylation negative regulation of B cell activation negative regulation of B cell activation negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction protein tyrosine kinase binding protein tyrosine kinase binding |
|
| 1433441_at |
Fbxl5 |
F-box and leucine-rich repeat protein 5 |
5 |
-43757748, -43744617 |
BQ173911 |
242960 |
33 |
iron ion binding nucleus cytoplasm intracellular iron ion homeostasis protein ubiquitination SCF ubiquitin ligase complex SCF ubiquitin ligase complex protein catabolic process SCF-dependent proteasomal ubiquitin-dependent protein catabolic process SCF-dependent proteasomal ubiquitin-dependent protein catabolic process positive regulation of protein catabolic process metal ion binding perinuclear region of cytoplasm iron-sulfur cluster binding multicellular organismal-level iron ion homeostasis multicellular organismal-level iron ion homeostasis |
|
| 1455026_at |
Sbno1 |
strawberry notch 1 |
5 |
-124368701, -124368701 |
BE947961 |
243272 |
25 |
nucleus regulation of DNA-templated transcription regulation of DNA-templated transcription chromatin DNA binding histone binding |
|
| 1456061_at |
Gimap8 |
GTPase, IMAP family member 8 |
6 |
48647360, 48647233, 48647360 |
BM243674 |
243374 |
14 |
nucleotide binding GTP binding cytoplasm mitochondrion endoplasmic reticulum endoplasmic reticulum Golgi apparatus regulation of T cell apoptotic process |
|
| 1452463_x_at |
Igk |
immunoglobulin kappa chain complex |
6 |
|
BG966217 |
243469 |
218 |
|
|
| 1426774_at |
Parp12 |
poly (ADP-ribose) polymerase family, member 12 |
6 |
-39086411 |
BM227980 |
243771 |
28 |
NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity cellular_component nucleus nucleus transferase activity glycosyltransferase activity nucleotidyltransferase activity metal ion binding protein auto-ADP-ribosylation NAD+-protein ADP-ribosyltransferase activity NAD+-protein ADP-ribosyltransferase activity |
|
| 1435955_at |
Siglecg |
sialic acid binding Ig-like lectin G |
7 |
43408279, 43408238 |
BE447170 |
243958 |
38 |
hematopoietic progenitor cell differentiation adaptive immune response immune system process negative regulation of immunoglobulin production protein binding plasma membrane plasma membrane cell adhesion cell adhesion membrane phosphatase binding carbohydrate binding regulation of B cell proliferation regulation of B cell proliferation sialic acid binding sialic acid binding SH2 domain binding innate immune response regulation of immune response negative regulation of calcium-mediated signaling negative regulation of inflammatory response to wounding |
|
| 1436590_at |
Ppp1r3b |
protein phosphatase 1, regulatory subunit 3B |
8 |
35375758, 35376661 |
BG071940 |
244416 |
21 |
protein phosphatase type 1 complex protein phosphatase type 1 complex phosphoprotein phosphatase activity carbohydrate metabolic process glycogen metabolic process regulation of glycogen biosynthetic process regulation of glycogen biosynthetic process regulation of glycogen catabolic process protein phosphatase 1 binding protein phosphatase regulator activity enzyme binding glycogen granule [phosphorylase] phosphatase activity glycogen binding |
04910 |
| 1442434_at |
Prag1 |
PEAK1 related kinase activating pseudokinase 1 |
8 |
36094827 |
BM195829 |
244418 |
23 |
protein kinase activity protein kinase activity protein binding ATP binding nucleus cytoplasm focal adhesion protein phosphorylation protein phosphorylation regulation of cell shape regulation of Notch signaling pathway negative regulation of neuron projection development cell migration positive regulation of Rho protein signal transduction identical protein binding anchoring junction regulation of cell motility |
|
| 1456485_at |
Npat |
nuclear protein in the AT region |
9 |
53537046 |
BM207451 |
244879 |
31 |
in utero embryonic development transcription coregulator activity transcription coactivator activity transcription corepressor activity nucleus nucleus nucleoplasm cytoplasm cell cycle Cajal body cell cycle G1/S phase transition positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II Gemini of coiled bodies |
|
| 1427197_at |
Atr |
ataxia telangiectasia and Rad3 related |
9 |
95857596 |
AF236887 |
245000 |
150 |
DNA damage checkpoint signaling DNA damage checkpoint signaling DNA damage checkpoint signaling nucleotide binding telomere maintenance male germ cell nucleus XY body DNA binding protein kinase activity protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleus nuclear envelope nucleoplasm nucleoplasm chromosome Golgi apparatus nucleobase-containing compound metabolic process DNA repair double-strand break repair protein phosphorylation protein phosphorylation DNA damage response DNA damage response embryo implantation negative regulation of DNA replication response to mechanical stimulus kinase activity phosphorylation PML body transferase activity peptidyl-serine phosphorylation replication fork processing positive regulation of telomere maintenance via telomerase MutLalpha complex binding MutSalpha complex binding cellular response to UV histone H2AXS139 kinase activity regulation of protein binding positive regulation of DNA damage response, signal transduction by p53 class mediator protein autophosphorylation nuclear membrane disassembly chromosome organization protein localization to chromosome, telomeric region ATR-ATRIP complex ATR-ATRIP complex cellular response to gamma radiation replicative senescence site of DNA damage establishment of RNA localization to telomere positive regulation of telomerase catalytic core complex assembly regulation of double-strand break repair |
04110 04115 |
| 1423411_at |
Rbm47 |
RNA binding motif protein 47 |
5 |
-66016548, -66016548, -66016548 |
BI099836 |
245945 |
30 |
regulation of alternative mRNA splicing, via spliceosome hematopoietic progenitor cell differentiation nucleic acid binding RNA binding RNA binding mRNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleus cytoplasm mRNA processing RNA splicing cytidine to uridine editing cytidine to uridine editing cytidine to uridine editing enzyme binding apolipoprotein B mRNA editing enzyme complex positive regulation of interleukin-10 production positive regulation of type I interferon-mediated signaling pathway 3'-UTR-mediated mRNA stabilization 3'-UTR-mediated mRNA stabilization enzyme-substrate adaptor activity enzyme-substrate adaptor activity |
|
| 1433811_at |
Mllt6 |
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6 |
11 |
97663411 |
BG245272 |
246198 |
28 |
renal system process nucleus chromatin organization regulation of transcription by RNA polymerase II positive regulation of sodium ion transport nucleosome binding nucleosome binding negative regulation of urine volume renal sodium excretion renal potassium excretion histone binding histone binding positive regulation of transcription by RNA polymerase II renal water absorption |
|
| 1425225_at |
Fcgr4 |
Fc receptor, IgG, low affinity IV |
1 |
171018925 |
BC027310 |
246256 |
55 |
antibody-dependent cellular cytotoxicity immune system process dendritic cell antigen processing and presentation extracellular space plasma membrane plasma membrane cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane cell surface cell surface membrane IgE receptor activity IgG receptor activity IgG receptor activity low-affinity IgG receptor activity IgE binding IgG binding Fc-gamma receptor III complex GPI anchor binding perforin production neutrophil activation natural killer cell degranulation positive regulation of bone resorption cellular response to lipopolysaccharide immune receptor activity immune receptor activity Fc receptor-mediated immune complex endocytosis |
04145 04380 04650 05140 05150 05322 |
| 1435264_at |
Emilin2 |
elastin microfibril interfacer 2 |
17 |
-71252171, -71252171 |
BB811788 |
246707 |
29 |
extracellular region collagen trimer cell adhesion extracellular matrix constituent conferring elasticity positive regulation of blood coagulation negative regulation of cell migration positive regulation of apoptotic process positive regulation of angiogenesis collagen-containing extracellular matrix collagen-containing extracellular matrix positive regulation of defense response to bacterium positive regulation of platelet aggregation |
|
| 1425374_at |
Oas3 |
2'-5' oligoadenylate synthetase 3 |
5 |
-120753097 |
AB067534 |
246727 |
20 |
nucleotide binding 2'-5'-oligoadenylate synthetase activity 2'-5'-oligoadenylate synthetase activity 2'-5'-oligoadenylate synthetase activity immune system process RNA binding double-stranded RNA binding double-stranded RNA binding double-stranded RNA binding ATP binding nucleus nucleoplasm nucleoplasm cytoplasm cytosol cytosol plasma membrane response to virus membrane transferase activity nucleotidyltransferase activity positive regulation of interferon-beta production positive regulation of tumor necrosis factor production negative regulation of chemokine (C-X-C motif) ligand 9 production RIG-I signaling pathway MDA-5 signaling pathway defense response to bacterium negative regulation of viral genome replication negative regulation of viral genome replication innate immune response metal ion binding defense response to virus defense response to virus negative regulation of type I interferon-mediated signaling pathway regulation of ribonuclease activity regulation of ribonuclease activity positive regulation of monocyte chemotactic protein-1 production negative regulation of chemokine (C-C motif) ligand 5 production negative regulation of IP-10 production negative regulation of chemokine (C-X-C motif) ligand 2 production |
05160 |
| 1425065_at |
Oas2 |
2'-5' oligoadenylate synthetase 2 |
5 |
-120730332 |
AB067535 |
246728 |
29 |
nucleotide binding 2'-5'-oligoadenylate synthetase activity 2'-5'-oligoadenylate synthetase activity 2'-5'-oligoadenylate synthetase activity immune system process RNA binding double-stranded RNA binding double-stranded RNA binding double-stranded RNA binding ATP binding nucleoplasm cytoplasm cytosol RNA catabolic process response to virus response to bacterium membrane transferase activity nucleotidyltransferase activity positive regulation of interferon-beta production positive regulation of tumor necrosis factor production defense response to bacterium negative regulation of viral genome replication innate immune response metal ion binding perinuclear region of cytoplasm defense response to virus defense response to virus type I interferon-mediated signaling pathway regulation of ribonuclease activity interleukin-27-mediated signaling pathway interleukin-27-mediated signaling pathway regulation of lactation |
05160 |
| 1427994_at |
Cd300lf |
CD300 molecule like family member F |
11 |
-115116213 |
BM230330 |
246746 |
57 |
virus receptor activity phosphatidylserine binding immune system process transmembrane signaling receptor activity interleukin-4 receptor binding protein binding plasma membrane plasma membrane lipid binding membrane osteoclast differentiation negative regulation of mast cell activation negative regulation of mast cell activation negative regulation of MyD88-dependent toll-like receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway interleukin-13-mediated signaling pathway identical protein binding ceramide binding ceramide binding positive regulation of interleukin-4-mediated signaling pathway negative regulation of apoptotic cell clearance positive regulation of apoptotic cell clearance positive regulation of apoptotic cell clearance |
|
| 1455735_at |
Ap1s3 |
adaptor-related protein complex AP-1, sigma 3 |
1 |
-79606875 |
AW259574 |
252903 |
20 |
molecular_function lysosomal membrane early endosome Golgi apparatus clathrin-coated pit protein targeting intracellular protein transport protein transport membrane vesicle-mediated transport vesicle-mediated transport membrane coat AP-1 adaptor complex cytoplasmic vesicle trans-Golgi network membrane clathrin adaptor activity intracellular membrane-bounded organelle intracellular membrane-bounded organelle platelet dense granule organization melanosome assembly |
04142 |
| 1419722_at |
Klk8 |
kallikrein related-peptidase 8 |
7 |
43797576 |
NM_008940 |
259277 |
54 |
serine-type endopeptidase activity serine-type endopeptidase activity extracellular region extracellular space cytoplasm cytoplasm proteolysis memory memory peptidase activity peptidase activity serine-type peptidase activity response to wounding hydrolase activity secretory granule keratinocyte proliferation neuron projection morphogenesis neuron projection morphogenesis regulation of synapse organization synapse organization serine protease inhibitor complex |
|
| 1427711_a_at |
Ceacam1 |
CEA cell adhesion molecule 1 |
7 |
-25461701 |
X15351 |
26365 |
158 |
regulation of cell growth blood vessel development negative regulation of cytokine production regulation of immune system process negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target actin binding granulocyte colony-stimulating factor receptor binding protein binding calmodulin binding extracellular space plasma membrane plasma membrane plasma membrane cell-cell junction adherens junction negative regulation of protein kinase activity cell adhesion signal transduction external side of plasma membrane basal plasma membrane cell surface cell surface cell surface regulation of endothelial cell migration bile acid transmembrane transporter activity bile acid and bile salt transport membrane basolateral plasma membrane apical plasma membrane lateral plasma membrane kinase binding protein kinase binding protein phosphatase binding cell junction negative regulation of granulocyte differentiation filamin binding cytoplasmic vesicle negative regulation of interleukin-1 production cellular response to insulin stimulus GPI anchor binding Toll-like receptor binding common myeloid progenitor cell proliferation insulin receptor internalization granulocyte colony-stimulating factor signaling pathway regulation of epidermal growth factor receptor signaling pathway regulation of epidermal growth factor receptor signaling pathway T cell receptor complex negative regulation of T cell proliferation identical protein binding protein homodimerization activity cell projection negative regulation of vascular permeability positive regulation of MAP kinase activity protein-containing complex binding cell-cell junction organization regulation of endothelial cell differentiation negative regulation of osteoclast differentiation negative regulation of fatty acid biosynthetic process negative regulation of bone resorption protein heterodimerization activity protein dimerization activity negative regulation of lipid biosynthetic process regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction ciliary membrane regulation of blood vessel remodeling transforming growth factor beta ligand-receptor complex anchoring junction regulation of ERK1 and ERK2 cascade negative regulation of platelet aggregation cell-cell adhesion via plasma-membrane adhesion molecules insulin catabolic process insulin catabolic process regulation of homophilic cell adhesion positive regulation of homophilic cell adhesion regulation of sprouting angiogenesis protein tyrosine kinase binding protein tyrosine kinase binding protein tyrosine kinase binding negative regulation of hepatocyte proliferation negative regulation of hepatocyte proliferation positive regulation of vasculogenesis |
|
| 1417074_at |
Ceacam10 |
CEA cell adhesion molecule 10 |
7 |
24777203, 24777166 |
NM_007675 |
26366 |
20 |
regulation of immune system process plasma membrane signal transduction cell surface protein tyrosine kinase binding |
|
| 1419515_at |
Fgd2 |
FYVE, RhoGEF and PH domain containing 2 |
17 |
29360913 |
NM_013710 |
26382 |
25 |
ruffle guanyl-nucleotide exchange factor activity nucleus cytoplasm cytoplasm endosome early endosome cytoskeleton plasma membrane cytoskeleton organization membrane cell projection positive regulation of JUN kinase activity filopodium assembly metal ion binding phosphatidylinositol phosphate binding |
|
| 1457666_s_at |
Ifi202b |
interferon activated gene 202B |
1 |
-173962568 |
AV229143 |
26388 |
54 |
cellular response to interferon-beta |
04623 |
| 1424850_at |
Map3k1 |
mitogen-activated protein kinase kinase kinase 1 |
13 |
-111746427 |
L13103 |
26401 |
113 |
MAPK cascade nucleotide binding protein polyubiquitination morphogenesis of an epithelial sheet epithelial cell morphogenesis protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity JUN kinase kinase kinase activity JUN kinase kinase kinase activity MAP kinase kinase activity MAP kinase kinase kinase activity ubiquitin-protein transferase activity protein binding ATP binding cytoplasm cytosol protein phosphorylation ubiquitin-dependent protein catabolic process transforming growth factor beta receptor signaling pathway JNK cascade cytoskeletal protein binding zinc ion binding JUN kinase binding apoptotic mitochondrial changes kinase activity phosphorylation transferase activity protein kinase binding cell junction regulation of cell migration positive regulation of actin filament polymerization mitogen-activated protein kinase kinase binding filamentous actin negative regulation of actin filament bundle assembly wound healing camera-type eye development positive regulation of apoptotic process positive regulation of MAPK cascade positive regulation of JUN kinase activity protein-containing complex binding positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of JNK cascade sphingolipid binding metal ion binding positive regulation of viral transcription mitogen-activated protein kinase binding eyelid development in camera-type eye positive regulation of canonical Wnt signaling pathway |
04010 04120 04622 04722 04912 |
| 1455597_at |
Map3k2 |
mitogen-activated protein kinase kinase kinase 2 |
18 |
32163088 |
AV024458 |
26405 |
52 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding nucleus nucleoplasm cytoplasm cytoplasm cytosol protein phosphorylation kinase activity phosphorylation transferase activity protein kinase binding intracellular signal transduction metal ion binding |
04010 04540 04912 |
| 1459800_s_at |
Map3k4 |
mitogen-activated protein kinase kinase kinase 4 |
17 |
-12227620, -12227620 |
AV079128 |
26407 |
82 |
MAPK cascade nucleotide binding placenta development protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding cytoplasm cytoplasm protein phosphorylation response to UV-C regulation of gene expression kinase activity phosphorylation transferase activity male germ-line sex determination positive regulation of telomere maintenance via telomerase intracellular signal transduction positive regulation of JUN kinase activity positive regulation of JUN kinase activity positive regulation of JUN kinase activity metal ion binding determination of dorsal identity positive regulation of telomerase activity chorionic trophoblast cell differentiation positive regulation of p38MAPK cascade positive regulation of telomere capping |
04010 04912 |
| 1439323_a_at |
Map4k1 |
mitogen-activated protein kinase kinase kinase kinase 1 |
7 |
28982049, 28982853 |
BB546619 |
26411 |
41 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding ATP binding cytoplasm protein phosphorylation protein phosphorylation protein phosphorylation JNK cascade cell population proliferation MAP kinase kinase kinase kinase activity MAP kinase kinase kinase kinase activity kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation intracellular signal transduction intracellular signal transduction positive regulation of MAPK cascade protein autophosphorylation cellular response to phorbol 13-acetate 12-myristate |
04010 |
| 1434833_at |
Map4k2 |
mitogen-activated protein kinase kinase kinase kinase 2 |
19 |
6341159 |
BB667222 |
26412 |
17 |
nucleotide binding immune system process protein kinase activity protein serine/threonine kinase activity ATP binding cytoplasm cytoplasm Golgi apparatus plasma membrane protein phosphorylation protein phosphorylation vesicle targeting MAP kinase kinase kinase kinase activity MAP kinase kinase kinase kinase activity membrane kinase activity phosphorylation transferase activity mitogen-activated protein kinase kinase kinase binding intracellular signal transduction intracellular signal transduction positive regulation of JUN kinase activity innate immune response positive regulation of JNK cascade |
04010 |
| 1448871_at |
Mapk13 |
mitogen-activated protein kinase 13 |
17 |
28769316 |
NM_011950 |
26415 |
68 |
MAPK cascade nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity MAP kinase activity ATP binding nucleus nucleoplasm cytoplasm protein phosphorylation response to osmotic stress cell cycle kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation positive regulation of interleukin-6 production cellular response to UV intracellular signal transduction stress-activated MAPK cascade cellular response to hydrogen peroxide cellular response to interleukin-1 cellular response to sorbitol cellular response to anisomycin cellular response to sodium arsenite |
04010 04370 04380 04620 04621 04622 04660 04664 04670 04722 04912 04914 05014 05140 05142 05145 05160 |
| 1419165_at |
Zfp260 |
zinc finger protein 260 |
7 |
30095075 |
D45210 |
26466 |
24 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus nucleus nucleoplasm cytosol regulation of transcription by RNA polymerase II multicellular organism development metal ion binding |
|
| 1452261_at |
Shprh |
SNF2 histone linker PHD RING helicase |
10 |
11149429, 11149429, 11149429 |
BC006883 |
268281 |
24 |
nucleotide binding protein polyubiquitination protein polyubiquitination nucleosome DNA binding helicase activity ubiquitin-protein transferase activity ATP binding cellular_component DNA repair nucleosome assembly DNA damage response DNA damage response transferase activity hydrolase activity ubiquitin protein ligase binding metal ion binding ubiquitin protein ligase activity ubiquitin protein ligase activity ATP-dependent chromatin remodeler activity |
|
| 1427417_at |
Scml4 |
Scm polycomb group protein like 4 |
10 |
42860511, 42860511 |
BB212066 |
268297 |
14 |
chromatin binding nucleus nucleus histone binding negative regulation of DNA-templated transcription |
|
| 1446715_at |
Abca13 |
ATP-binding cassette, sub-family A member 13 |
11 |
9191941 |
BB503961 |
268379 |
22 |
nucleotide binding lipid transporter activity ATP binding lipid transport lipid transport membrane ATP hydrolysis activity cytoplasmic vesicle positive regulation of cholesterol transport positive regulation of cholesterol transport ceramide transport ATPase-coupled transmembrane transporter activity intracellular membrane-bounded organelle transmembrane transport intracellular vesicle intracellular vesicle ABC-type transporter activity positive regulation of synaptic vesicle endocytosis |
02010 |
| 1458148_at |
Nlrc3 |
NLR family, CARD domain containing 3 |
16 |
-3945006 |
BB466171 |
268857 |
31 |
nucleotide binding protein binding ATP binding cytoplasm cytoplasm cytosol cytosol canonical NF-kappaB signal transduction canonical NF-kappaB signal transduction canonical NF-kappaB signal transduction regulation of protein ubiquitination regulation of protein ubiquitination negative regulation of NF-kappaB transcription factor activity negative regulation of NF-kappaB transcription factor activity response to lipopolysaccharide negative regulation of interferon-alpha production negative regulation of interferon-beta production negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production negative regulation of interleukin-6 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production negative regulation of tumor necrosis factor production centriolar satellite intracellular signal transduction phosphatidylinositol 3-kinase regulatory subunit binding T cell activation negative regulation of canonical NF-kappaB signal transduction negative regulation of canonical NF-kappaB signal transduction negative regulation of canonical NF-kappaB signal transduction negative regulation of canonical NF-kappaB signal transduction negative regulation of canonical NF-kappaB signal transduction intracellular membrane-bounded organelle negative regulation of innate immune response negative regulation of fibroblast proliferation perinuclear region of cytoplasm negative regulation of epithelial cell proliferation negative regulation of inflammatory response negative regulation of inflammatory response negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction molecular function inhibitor activity negative regulation of cytokine production involved in inflammatory response negative regulation of NLRP3 inflammasome complex assembly negative regulation of non-canonical NF-kappaB signal transduction |
|
| 1422013_at |
Clec4a2 |
C-type lectin domain family 4, member a2 |
6 |
123122689, 123123315 |
NM_011999 |
26888 |
32 |
adaptive immune response immune system process calcium ion binding mannose binding plasma membrane external side of plasma membrane membrane carbohydrate binding carbohydrate binding carbohydrate binding innate immune response metal ion binding antifungal innate immune response |
|
| 1442339_at |
Stfa2l1 |
stefin A2 like 1 |
16 |
36156810 |
BB667930 |
268885 |
10 |
cornified envelope protease binding cysteine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity extracellular space nucleoplasm cytoplasm cytosol cytosol negative regulation of peptidase activity peptide cross-linking keratinocyte differentiation negative regulation of proteolysis cell-cell adhesion peptidase inhibitor complex |
|
| 1455745_at |
Cln8 |
CLN8 transmembrane ER and ERGIC protein |
8 |
14888535 |
BM249363 |
26889 |
87 |
protein binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment phospholipid metabolic process phospholipid metabolic process phospholipid metabolic process ceramide metabolic process apoptotic process mitochondrial membrane organization lysosome organization nervous system development nervous system development visual perception adult walking behavior cholesterol metabolic process associative learning adult locomotory behavior regulation of cell size macromolecule catabolic process membrane protein metabolic process spinal cord motor neuron differentiation somatic motor neuron differentiation protein catabolic process social behavior negative regulation of neuron apoptotic process photoreceptor cell maintenance musculoskeletal movement neuromuscular process controlling posture neuromuscular process controlling balance negative regulation of transferase activity neuron apoptotic process glutamate reuptake lipid homeostasis retina development in camera-type eye neurofilament cytoskeleton organization ceramide binding ceramide binding retinal rod cell apoptotic process |
|
| 1435641_at |
Mgat4a |
mannoside acetylglucosaminyltransferase 4, isoenzyme A |
1 |
-37439339, -37439339 |
BB109391 |
269181 |
21 |
extracellular region endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment Golgi apparatus Golgi stack protein glycosylation protein N-linked glycosylation protein N-linked glycosylation N-glycan processing acetylglucosaminyltransferase activity acetylglucosaminyltransferase activity alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity membrane transferase activity glycosyltransferase activity metal ion binding |
00510 01100 |
| 1433794_at |
Setx |
senataxin |
2 |
29124991 |
BM211942 |
269254 |
43 |
MAPK cascade nucleotide binding nuclear chromosome chromosome, telomeric region transcription termination site sequence-specific DNA binding transcription termination site sequence-specific DNA binding RNA binding helicase activity protein binding ATP binding nucleus nucleoplasm chromosome cytoplasm DNA repair double-strand break repair DNA recombination DNA-templated transcription termination termination of RNA polymerase II transcription termination of RNA polymerase II transcription mRNA splice site recognition DNA damage response spermatogenesis nervous system development circadian rhythm fibroblast growth factor receptor signaling pathway positive regulation of neuron projection development nuclear body nuclear body hydrolase activity cell differentiation axon growth cone positive regulation of RNA splicing cellular response to oxidative stress identical protein binding cell projection negative regulation of apoptotic process phosphatidylinositol 3-kinase/protein kinase B signal transduction cellular response to fibroblast growth factor stimulus intercellular bridge positive regulation of transcription by RNA polymerase II rhythmic process positive regulation of termination of DNA-templated transcription cellular response to hydrogen peroxide cellular response to retinoic acid positive regulation of DNA-templated transcription initiation positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled |
|
| 1435655_at |
Rpl12 |
ribosomal protein L12 |
2 |
32961711 |
BG807990 |
269261 |
38 |
cytoplasmic translation RNA binding structural constituent of ribosome structural constituent of ribosome protein binding nucleus nucleolus cytoplasm cytosol ribosome translation translation postsynaptic density cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome synapse synapse synapse large ribosomal subunit rRNA binding large ribosomal subunit rRNA binding presynapse postsynapse translation at presynapse translation at postsynapse ribonucleoprotein complex |
03010 |
| 1456038_at |
Fbxl4 |
F-box and leucine-rich repeat protein 4 |
4 |
22357542 |
BB003709 |
269514 |
20 |
autophagy of mitochondrion autophagy of mitochondrion nucleus cytoplasm mitochondrion mitochondrial intermembrane space nuclear speck SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
|
| 1439464_s_at |
Tex10 |
testis expressed gene 10 |
4 |
-48430857 |
AV278060 |
269536 |
25 |
nucleus nucleus nucleoplasm cytoplasm mitochondrion MLL1 complex MLL1 complex |
|
| 1435004_at |
Pank4 |
pantothenate kinase 4 |
4 |
154964122 |
BM119773 |
269614 |
25 |
nucleotide binding pantothenate kinase activity pantothenate kinase activity ATP binding extracellular space nucleus cytoplasm cytosol cytosol cytosol coenzyme A biosynthetic process coenzyme A biosynthetic process coenzyme A catabolic process coenzyme A catabolic process hydrolase activity phosphatase activity metal ion binding |
00770 01100 |
| 1434935_at |
Aak1 |
AP2 associated kinase 1 |
6 |
86849504, 86849283, 86849504 |
BG067888 |
269774 |
36 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity Notch binding ATP binding cytosol plasma membrane clathrin-coated pit protein phosphorylation protein phosphorylation endocytosis membrane kinase activity phosphorylation transferase activity cell leading edge regulation of protein localization AP-2 adaptor complex binding AP-2 adaptor complex binding cell projection terminal bouton intracellular membrane-bounded organelle calyx of Held synapse positive regulation of Notch signaling pathway protein stabilization clathrin complex presynapse presynapse presynapse presynaptic endocytosis presynaptic endocytosis presynaptic endocytosis regulation of clathrin-dependent endocytosis regulation of clathrin-dependent endocytosis |
|
| 1456411_at |
Rccd1 |
RCC1 domain containing 1 |
7 |
-80316615 |
BM218704 |
269955 |
14 |
molecular_function chromosome cytosol plasma membrane chromatin organization biological_process |
|
| 1434945_at |
Lpcat2 |
lysophosphatidylcholine acyltransferase 2 |
8 |
92855332 |
AW743924 |
270084 |
26 |
1-acylglycerol-3-phosphate O-acyltransferase activity calcium ion binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus Golgi stack lipid droplet plasma membrane lipid metabolic process platelet activating factor biosynthetic process O-acyltransferase activity phospholipid biosynthetic process membrane transferase activity acyltransferase activity phosphatidylcholine acyl-chain remodeling lysophosphatidic acid acyltransferase activity metal ion binding 1-alkenylglycerophosphocholine O-acyltransferase activity 1-acylglycerophosphocholine O-acyltransferase activity 1-acylglycerophosphocholine O-acyltransferase activity 1-alkylglycerophosphocholine O-acetyltransferase activity plasmalogen synthase activity membrane organization |
00564 00565 01100 |
| 1433661_at |
Nlrx1 |
NLR family member X1 |
9 |
-44252712, -44252712, -44252712 |
BB830346 |
270151 |
63 |
nucleotide binding immune system process protein binding ATP binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane plasma membrane macrophage cytokine production negative regulation of macrophage cytokine production membrane interferon-beta production interleukin-6 production negative regulation of interferon-beta production negative regulation of interleukin-6 production negative regulation of RIG-I signaling pathway negative regulation of canonical NF-kappaB signal transduction negative regulation of canonical NF-kappaB signal transduction innate immune response negative regulation of innate immune response negative regulation of inflammatory response |
04622 |
| 1418398_a_at |
Tspan32 |
tetraspanin 32 |
7 |
143005658, 143005045 |
AF175771 |
27027 |
32 |
molecular_function intracellular anatomical structure cytoskeleton organization integrin-mediated signaling pathway blood coagulation hemostasis cell surface membrane negative regulation of myeloid dendritic cell activation T cell proliferation negative regulation of T cell proliferation defense response to protozoan regulation of defense response to virus integrin alphaIIb-beta3 complex platelet aggregation |
|
| 1433966_x_at |
Asns |
asparagine synthetase |
6 |
-7675164 |
AV212753 |
27053 |
41 |
nucleotide binding asparagine synthase (glutamine-hydrolyzing) activity asparagine synthase (glutamine-hydrolyzing) activity ATP binding cytosol cytosol cytosol asparagine biosynthetic process asparagine biosynthetic process glutamine metabolic process amino acid biosynthetic process ligase activity cellular response to glucose starvation identical protein binding negative regulation of apoptotic process positive regulation of mitotic cell cycle |
00250 00910 01100 |
| 1418397_at |
Zfp275 |
zinc finger protein 275 |
X |
73342619, 73342620 |
BC019962 |
27081 |
33 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II |
|
| 1443932_at |
Klhdc1 |
kelch domain containing 1 |
12 |
69241831 |
BQ176961 |
271005 |
10 |
cytoplasm cytosol Cul5-RING ubiquitin ligase complex ubiquitin-dependent protein catabolic process via the C-end degron rule pathway ubiquitin ligase-substrate adaptor activity |
|
| 1454826_at |
Zbtb11 |
zinc finger and BTB domain containing 11 |
16 |
55973803 |
BM195115 |
271377 |
21 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus nucleoplasm regulation of DNA-templated transcription metal ion binding |
|
| 1430154_at |
Vps13a |
vacuolar protein sorting 13A |
19 |
-16615365 |
AI666321 |
271564 |
32 |
molecular_function mitochondrion mitochondrial outer membrane lysosome lysosomal membrane endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus lipid droplet protein targeting to vacuole lipid transport autophagy autophagy nervous system development locomotory behavior endosome membrane membrane flagellated sperm motility sperm mitochondrion organization dense core granule cytoplasmic vesicle mitochondrial membrane social behavior mitochondria-associated endoplasmic reticulum membrane protein retention in Golgi apparatus sperm midpiece neuronal dense core vesicle lumen lysosomal protein catabolic process |
|
| 1426956_a_at |
Trp53bp1 |
transformation related protein 53 binding protein 1 |
2 |
-121194834 |
AJ414734 |
27223 |
200 |
DNA damage checkpoint signaling chromosome, centromeric region kinetochore chromosome, telomeric region chromosome, telomeric region p53 binding DNA binding damaged DNA binding transcription coregulator activity protein binding nucleus nucleus nucleus nucleoplasm replication fork chromosome cytoplasm DNA repair double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining regulation of DNA-templated transcription DNA damage response transcription factor binding nuclear body nuclear body methylated histone binding methylated histone binding site of double-strand break site of double-strand break telomeric DNA binding histone binding sequence-specific DNA binding positive regulation of isotype switching positive regulation of isotype switching positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein homooligomerization RNA polymerase II-specific DNA-binding transcription factor binding ubiquitin modification-dependent histone binding double-strand break repair via classical nonhomologous end joining histone reader activity DNA repair complex negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination |
|
| 1430700_a_at |
Pla2g7 |
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
17 |
43568450 |
AK005158 |
27226 |
59 |
1-alkyl-2-acetylglycerophosphocholine esterase activity 1-alkyl-2-acetylglycerophosphocholine esterase activity phospholipid binding extracellular region extracellular space lipid metabolic process inflammatory response phospholipid catabolic process lipid catabolic process hydrolase activity low-density lipoprotein particle high-density lipoprotein particle low-density lipoprotein particle remodeling lipid oxidation plasma lipoprotein particle oxidation phosphatidylcholine catabolic process platelet activating factor metabolic process calcium-independent phospholipase A2 activity platelet activating factor catabolic process positive regulation of monocyte chemotaxis |
00565 01100 |
| 1460407_at |
Spib |
Spi-B transcription factor (Spi-1/PU.1 related) |
7 |
-44525994 |
BM244106 |
272382 |
62 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific immature B cell differentiation DNA binding DNA-binding transcription factor activity nucleus nucleus transcription regulator complex regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cell differentiation macrophage differentiation sequence-specific DNA binding positive regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding |
|
| 1459522_s_at |
Gyg1 |
glycogenin 1 |
3 |
-20122083, -20122082 |
AU017667 |
27357 |
41 |
glucose binding cytoplasm glycogen biosynthetic process glycogen biosynthetic process glycogen biosynthetic process glycogenin glucosyltransferase activity glycogenin glucosyltransferase activity transferase activity glycosyltransferase activity glycosyltransferase activity manganese ion binding protein homodimerization activity metal ion binding UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity |
|
| 1423298_at |
Add3 |
adducin 3 |
19 |
53140442, 53142755, 53143996 |
BM239842 |
27360 |
36 |
condensed nuclear chromosome actin binding protein kinase C binding structural constituent of cytoskeleton calmodulin binding cytoplasm cytoskeleton cytoskeleton plasma membrane plasma membrane brush border cell-cell junction cell cortex response to xenobiotic stimulus postsynaptic density postsynaptic density membrane positive regulation of vasoconstriction actin filament binding barbed-end actin filament capping positive regulation of cytoskeleton organization |
|
| 1457753_at |
Tlr13 |
toll-like receptor 13 |
X |
106143274 |
BI655907 |
279572 |
34 |
toll-like receptor signaling pathway toll-like receptor signaling pathway immune system process MyD88-dependent toll-like receptor signaling pathway RNA binding transmembrane signaling receptor activity protein binding cytoplasm endosome inflammatory response inflammatory response immune response signal transduction response to virus membrane rRNA binding toll-like receptor 13 signaling pathway signaling receptor activity identical protein binding regulation of MAPK cascade innate immune response |
|
| 1435357_at |
Rsrp1 |
arginine/serine rich protein 1 |
4 |
134923624 |
BE652553 |
27981 |
21 |
spliceosomal complex assembly molecular_function cellular_component nucleus biological_process |
|
| 1437478_s_at |
Efhd2 |
EF hand domain containing 2 |
4 |
-141858141 |
AA409309 |
27984 |
52 |
calcium ion binding calcium ion binding protein binding membrane metal ion binding |
|
| 1417953_at |
Fam3c |
FAM3 metabolism regulating signaling molecule C |
6 |
-22306521 |
AK016470 |
27999 |
41 |
molecular_function extracellular region extracellular space Golgi apparatus multicellular organism development biological_process carbohydrate binding cytoplasmic vesicle |
|
| 1456531_x_at |
Prpf19 |
pre-mRNA processing factor 19 |
19 |
10898644, 10895230 |
BB458578 |
28000 |
44 |
DNA damage checkpoint signaling protein polyubiquitination spliceosomal tri-snRNP complex assembly spliceosomal complex assembly mRNA splicing, via spliceosome mRNA splicing, via spliceosome mRNA splicing, via spliceosome Prp19 complex Prp19 complex ubiquitin-protein transferase activity ubiquitin-protein transferase activity protein binding nucleus nucleus DNA replication factor A complex spliceosomal complex cytoplasm cytoplasm cytoskeleton DNA repair double-strand break repair via nonhomologous end joining mRNA processing DNA damage response protein localization RNA splicing lipid biosynthetic process proteasomal protein catabolic process proteasomal protein catabolic process protein ubiquitination nuclear speck transferase activity ubiquitin-ubiquitin ligase activity site of double-strand break identical protein binding positive regulation of mRNA splicing, via spliceosome positive regulation of astrocyte differentiation ubiquitin protein ligase activity protein K63-linked ubiquitination U2-type catalytic step 1 spliceosome U2-type catalytic step 2 spliceosome catalytic step 2 spliceosome |
03040 04120 |
| 1420129_s_at |
Rtcb |
RNA 2',3'-cyclic phosphate and 5'-OH ligase |
10 |
-85938636 |
AA409545 |
28088 |
39 |
nucleotide binding tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate in utero embryonic development placenta development RNA ligase (ATP) activity RNA ligase (ATP) activity GTP binding nucleus nucleus nuclear envelope nucleoplasm cytoplasm cytoplasm endoplasmic reticulum membrane cytosol tRNA splicing, via endonucleolytic cleavage and ligation RNA processing tRNA processing RNA ligase activity ligase activity vinculin binding intracellular membrane-bounded organelle metal ion binding tRNA-splicing ligase complex tRNA-splicing ligase complex |
|
| 1434746_at |
Mga |
MAX gene associated |
2 |
119897227 |
BG797579 |
29808 |
52 |
chromatin RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific cell fate specification DNA binding DNA-binding transcription factor activity nucleus nucleus transcription regulator complex regulation of DNA-templated transcription regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II protein dimerization activity MLL1 complex MLL1 complex cellular response to leukemia inhibitory factor |
|
| 1453365_at |
Rabgap1l |
RAB GTPase activating protein 1-like |
1 |
-160219173, -160256571 |
AK018430 |
29809 |
27 |
GTPase activator activity GTPase activator activity nucleus endosome early endosome Golgi apparatus endocytosis protein transport small GTPase binding small GTPase binding regulation of protein localization megakaryocyte development regulation of GTPase activity |
|
| 1415936_at |
Bcar3 |
breast cancer anti-estrogen resistance 3 |
3 |
122483568, 122419756 |
NM_013867 |
29815 |
27 |
phosphotyrosine residue binding lens morphogenesis in camera-type eye guanyl-nucleotide exchange factor activity protein binding cytoplasm focal adhesion epidermal growth factor receptor signaling pathway small GTPase-mediated signal transduction positive regulation of cell population proliferation insulin receptor signaling pathway membrane kinase binding positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation positive regulation of MAPK cascade positive regulation of GTPase activity anchoring junction endothelin receptor signaling pathway |
|
| 1425553_s_at |
Hip1r |
huntingtin interacting protein 1 related |
5 |
123973627 |
AA590970 |
29816 |
47 |
actin binding protein binding phospholipid binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm cytosol cytoskeleton plasma membrane clathrin-coated pit cell cortex endocytosis endocytosis receptor-mediated endocytosis receptor-mediated endocytosis activation of cysteine-type endopeptidase activity involved in apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process actin filament organization postsynaptic density membrane apical plasma membrane SH3 domain binding regulation of endocytosis clathrin-coated vesicle clathrin-coated vesicle clathrin-coated vesicle clathrin binding clathrin binding negative regulation of actin filament polymerization negative regulation of actin filament polymerization cytoplasmic vesicle clathrin light chain binding clathrin light chain binding positive regulation of protein binding ruffle membrane dendrite cytoplasm regulation of actin cytoskeleton organization regulation of actin cytoskeleton organization negative regulation of Arp2/3 complex-mediated actin nucleation phosphatidylinositol binding clathrin adaptor activity clathrin adaptor activity clathrin adaptor activity identical protein binding protein homodimerization activity protein homodimerization activity neuronal cell body positive regulation of apoptotic process negative regulation of apoptotic process dendritic spine intracellular membrane-bounded organelle phosphatidylinositol-3,4-bisphosphate binding phosphatidylinositol-3,4-bisphosphate binding positive regulation of epidermal growth factor receptor signaling pathway protein heterodimerization activity clathrin coat assembly clathrin coat assembly perinuclear region of cytoplasm protein stabilization actin filament binding actin filament binding actin filament binding digestive system development regulation of gastric acid secretion membrane organization phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-3,5-bisphosphate binding synaptic membrane postsynapse glutamatergic synapse postsynapse organization positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway positive regulation of clathrin coat assembly regulation of clathrin-dependent endocytosis positive regulation of clathrin-dependent endocytosis positive regulation of platelet-derived growth factor receptor-beta signaling pathway |
|
| 1452469_a_at |
Smtn |
smoothelin |
11 |
-3517521 |
BF578669 |
29856 |
32 |
negative regulation of systemic arterial blood pressure actin binding cytoplasm microtubule organizing center cytoskeleton actin cytoskeleton organization filamentous actin positive regulation of cardiac muscle contraction |
|
| 1419574_at |
Zfp292 |
zinc finger protein 292 |
4 |
-34803109 |
NM_013889 |
30046 |
35 |
DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA binding nucleus nucleus regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding |
|
| 1417928_at |
Pdlim4 |
PDZ and LIM domain 4 |
11 |
-54054927 |
NM_019417 |
30794 |
40 |
stress fiber stress fiber actin binding protein binding nucleus cytoplasm endosome cytoskeleton adherens junction heart development actin cytoskeleton membrane protein phosphatase binding protein phosphatase binding Z disc lamellipodium actin cytoskeleton organization actin cytoskeleton organization early endosome lumen filamentous actin filamentous actin recycling endosome lumen protein homodimerization activity actinin binding cell projection neuron projection dendritic spine synapse postsynaptic membrane metal ion binding perinuclear region of cytoplasm muscle alpha-actinin binding alpha-actinin binding positive regulation of stress fiber assembly muscle structure development excitatory chemical synaptic transmission |
|
| 1416858_a_at |
Fkbp3 |
FK506 binding protein 3 |
12 |
-65062431 |
NM_013902 |
30795 |
35 |
peptidyl-prolyl cis-trans isomerase activity protein binding nucleus isomerase activity |
|
| 1448420_a_at |
Fbxl12 |
F-box and leucine-rich repeat protein 12 |
9 |
-20637748, -20637748 |
NM_013911 |
30843 |
25 |
ubiquitin ligase complex cytoplasm ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
|
| 1425086_a_at |
Slamf6 |
SLAM family member 6 |
1 |
171917461, 171917461 |
AF248636 |
30925 |
48 |
natural killer cell differentiation natural killer cell proliferation adaptive immune response immune system process plasma membrane plasma membrane external side of plasma membrane membrane positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of interleukin-17 production T cell activation innate immune response positive regulation of natural killer cell mediated cytotoxicity T-helper 17 cell lineage commitment T-helper 17 cell lineage commitment |
|
| 1417010_at |
Zbtb18 |
zinc finger and BTB domain containing 18 |
1 |
177444660, 177445820, 177444652, 177442350, 177442350, 177444937 |
NM_013915 |
30928 |
46 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II heterochromatin DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific in utero embryonic development DNA binding nucleus nucleus nucleus nucleoplasm regulation of transcription by RNA polymerase II multicellular organism development skeletal muscle tissue development nuclear speck cerebellum development hippocampus development cerebral cortex development sequence-specific DNA binding negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II metal ion binding neuron development homeostasis of number of cells regulation of cell division sequence-specific double-stranded DNA binding |
|
| 1421998_at |
Tor3a |
torsin family 3, member A |
1 |
-156653616 |
NM_023141 |
30935 |
24 |
nucleotide binding protein binding ATP binding nuclear envelope cytoplasm endoplasmic reticulum endoplasmic reticulum lumen endoplasmic reticulum lumen endoplasmic reticulum lumen ATP hydrolysis activity |
|
| 1447854_s_at |
H2bc21 |
H2B clustered histone 21 |
3 |
96221071 |
AV127319 |
319190 |
25 |
nucleosome lipopolysaccharide binding innate immune response in mucosa DNA binding protein binding extracellular space nucleus nucleoplasm nucleoplasm chromosome cytosol plasma membrane negative regulation of tumor necrosis factor-mediated signaling pathway antibacterial humoral response structural constituent of chromatin killing of cells of another organism CENP-A containing nucleosome protein heterodimerization activity defense response to Gram-negative bacterium defense response to Gram-positive bacterium antimicrobial humoral immune response mediated by antimicrobial peptide |
05322 |
| 1434521_at |
Rfx7 |
regulatory factor X, 7 |
9 |
72532239 |
BB148972 |
319758 |
22 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding |
|
| 1441516_a_at |
C130050O18Rik |
RIKEN cDNA C130050O18 gene |
5 |
139406386, 139405283 |
BB527707 |
319772 |
10 |
molecular_function cellular_component biological_process |
|
| 1454795_at |
Cobll1 |
Cobl-like 1 |
2 |
-65088338 |
AV080881 |
319876 |
17 |
actin monomer binding |
|
| 1417321_at |
Zcchc7 |
zinc finger, CCHC domain containing 7 |
4 |
44756558 |
NM_138590 |
319885 |
24 |
molecular_function nucleic acid binding RNA binding nucleus nucleolus cytosol biological_process zinc ion binding TRAMP complex metal ion binding nuclear mRNA surveillance of mRNA 3'-end processing nuclear polyadenylation-dependent rRNA catabolic process nuclear polyadenylation-dependent snoRNA catabolic process nuclear polyadenylation-dependent snRNA catabolic process nuclear polyadenylation-dependent tRNA catabolic process nuclear polyadenylation-dependent CUT catabolic process |
03018 |
| 1426550_at |
Sidt1 |
SID1 transmembrane family, member 1 |
16 |
-44240179 |
AI449329 |
320007 |
21 |
RNA binding double-stranded RNA binding double-stranded RNA binding lysosome plasma membrane cholesterol binding membrane RNA transport RNA transmembrane transporter activity |
|
| 1437514_at |
Trem6l |
triggering receptor expressed on myeloid cells-like 6 |
17 |
48316161 |
BB134165 |
320148 |
11 |
cell surface signaling receptor activity |
|
| 1434397_at |
Zdhhc17 |
zinc finger, DHHC domain containing 17 |
10 |
-110941779, -110941779 |
BM248633 |
320150 |
46 |
Golgi membrane Golgi membrane signaling receptor binding protein binding Golgi apparatus Golgi apparatus plasma membrane axonogenesis membrane palmitoyltransferase activity palmitoyltransferase activity palmitoyltransferase activity transferase activity acyltransferase activity peptidyl-L-cysteine S-palmitoylation protein palmitoylation protein palmitoylation protein palmitoylation protein-cysteine S-myristoyltransferase activity protein-cysteine S-palmitoyltransferase activity protein-cysteine S-palmitoyltransferase activity Golgi-associated vesicle membrane cytoplasmic vesicle identical protein binding lipoprotein transport cell projection regulation of programmed cell death intracellular membrane-bounded organelle synapse regulation of neurotrophin TRK receptor signaling pathway regulation of ERK1 and ERK2 cascade protein-cysteine S-stearoyltransferase activity |
|
| 1427202_at |
Etfbkmt |
electron transfer flavoprotein beta subunit lysine methyltransferase |
6 |
149141512 |
AV002340 |
320204 |
15 |
cytoplasm mitochondrion mitochondrial matrix mitochondrial matrix methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity protein-lysine N-methyltransferase activity protein-lysine N-methyltransferase activity protein-lysine N-methyltransferase activity transferase activity peptidyl-lysine methylation peptidyl-lysine trimethylation peptidyl-lysine trimethylation peptidyl-lysine trimethylation heat shock protein binding methylation protein-containing complex negative regulation of electron transfer activity negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase |
|
| 1435266_at |
Scai |
suppressor of cancer cell invasion |
2 |
-39066214 |
BB495464 |
320271 |
24 |
transcription corepressor activity transcription corepressor activity transcription corepressor activity protein binding nucleus nucleus nucleoplasm cytoplasm DNA-templated transcription negative regulation of signal transduction membrane negative regulation of cell migration negative regulation of cell migration nuclear membrane negative regulation of Rho protein signal transduction |
|
| 1455132_at |
Rasal3 |
RAS protein activator like 3 |
17 |
-32390658, -32390658 |
AV312663 |
320484 |
20 |
GTPase activator activity cytoplasm identical protein binding regulation of GTPase activity negative regulation of Ras protein signal transduction positive regulation of NK T cell proliferation cytoplasmic side of membrane |
|
| 1455340_at |
Dennd5b |
DENN domain containing 5B |
6 |
-148988068 |
BB763709 |
320560 |
18 |
guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity membrane small GTPase binding small GTPase binding positive regulation of triglyceride transport |
|
| 1437202_at |
Mysm1 |
myb-like, SWIRM and MPN domains 1 |
4 |
-94942040 |
BB494594 |
320713 |
49 |
immune system process DNA binding transcription coactivator activity transcription coactivator activity nucleus nucleoplasm nucleolus cytoplasm chromatin organization chromatin remodeling chromatin remodeling proteolysis peptidase activity metallopeptidase activity hydrolase activity regulation of cell migration protein-containing complex histone binding histone binding pigmentation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding regulation of hair follicle development metal-dependent deubiquitinase activity histone H2A deubiquitinase activity regulation of hemopoiesis |
|
| 1442023_at |
A530030E21Rik |
RIKEN cDNA A530030E21 gene |
16 |
|
BB220605 |
320731 |
7 |
molecular_function cellular_component biological_process |
|
| 1437699_at |
E430014B02Rik |
RIKEN cDNA E430014B02 gene |
17 |
|
BB031353 |
320908 |
7 |
molecular_function cellular_component biological_process |
|
| 1454788_at |
Arl4c |
ADP-ribosylation factor-like 4C |
1 |
-88698225 |
BQ176306 |
320982 |
23 |
nucleotide binding GTPase activity GTP binding GTP binding cytoplasm cytoplasm cytosol plasma membrane intracellular protein transport membrane endocytic recycling endocytic recycling cell projection alpha-tubulin binding |
|
| 1428162_at |
Lrif1 |
ligand dependent nuclear receptor interacting factor 1 |
3 |
106721681, 106684986 |
AK008209 |
321000 |
16 |
chromosome, telomeric region Barr body Barr body protein binding nucleus nucleoplasm chromosome regulation of DNA-templated transcription dosage compensation by inactivation of X chromosome centriolar satellite nuclear retinoic acid receptor binding |
|
| 1437356_at |
Gpr183 |
G protein-coupled receptor 183 |
14 |
-121952330 |
BM242490 |
321019 |
67 |
adaptive immune response B cell activation involved in immune response mature B cell differentiation involved in immune response immune system process dendritic cell chemotaxis G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane humoral immune response signal transduction G protein-coupled receptor signaling pathway oxysterol binding oxysterol binding T cell chemotaxis membrane osteoclast differentiation leukocyte chemotaxis leukocyte chemotaxis positive regulation of B cell proliferation positive regulation of B cell proliferation dendritic cell homeostasis cell chemotaxis T follicular helper cell differentiation positive regulation of ERK1 and ERK2 cascade regulation of astrocyte chemotaxis |
|
| 1443698_at |
Xaf1 |
XIAP associated factor 1 |
11 |
72301628 |
BB645745 |
327959 |
21 |
nucleus nucleoplasm cytoplasm mitochondrion mitochondrion apoptotic process negative regulation of protein-containing complex assembly negative regulation of type I interferon production response to interferon-beta metal ion binding molecular sequestering activity |
|
| 1453160_at |
Med13 |
mediator complex subunit 13 |
11 |
-86267032 |
BB244704 |
327987 |
36 |
transcription coregulator activity transcription coactivator activity transcription coactivator activity nucleus nucleoplasm nucleoplasm regulation of transcription by RNA polymerase II mediator complex mediator complex mediator complex cholesterol homeostasis negative regulation of DNA-binding transcription factor activity positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II nuclear thyroid hormone receptor binding positive regulation of transcription initiation by RNA polymerase II triglyceride homeostasis CKM complex |
|
| 1428172_at |
Prpf39 |
pre-mRNA processing factor 39 |
12 |
65036333 |
BB460975 |
328110 |
18 |
commitment complex mRNA 5'-splice site recognition nucleus U1 snRNP RNA processing mRNA processing RNA splicing pre-mRNA 5'-splice site binding U2-type prespliceosome |
|
| 1435090_at |
Tubgcp6 |
tubulin, gamma complex component 6 |
15 |
-89099097 |
BB477000 |
328580 |
16 |
microtubule cytoskeleton organization mitotic cell cycle spindle pole equatorial microtubule organizing center gamma-tubulin complex gamma-tubulin ring complex cytoplasm centrosome centrosome microtubule organizing center cytoskeleton microtubule microtubule nucleation microtubule nucleation microtubule binding cytoplasmic microtubule organization gamma-tubulin binding gamma-tubulin binding microtubule minus-end binding spindle assembly meiotic cell cycle |
|
| 1438296_at |
Slc2a4rg-ps |
Slc2a4 regulator, pseudogene |
2 |
181384249 |
BE632919 |
329584 |
7 |
|
|
| 1452868_at |
Usp24 |
ubiquitin specific peptidase 24 |
4 |
106316212 |
AK012842 |
329908 |
26 |
cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity nucleus cytosol proteolysis peptidase activity cysteine-type peptidase activity protein deubiquitination protein deubiquitination hydrolase activity |
|
| 1438148_at |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
5 |
90786100 |
BB829808 |
330122 |
23 |
cytokine activity protein binding extracellular region extracellular space extracellular space chemotaxis defense response inflammatory response inflammatory response immune response positive regulation of cytosolic calcium ion concentration chemokine activity chemokine activity chemokine activity neutrophil chemotaxis neutrophil chemotaxis neutrophil chemotaxis CXCR chemokine receptor binding antimicrobial humoral immune response mediated by antimicrobial peptide chemokine-mediated signaling pathway cellular response to lipopolysaccharide |
|
| 1454762_at |
Xkrx |
X-linked Kx blood group related, X-linked |
X |
-134149042 |
BM932447 |
331524 |
14 |
molecular_function cellular_component biological_process membrane |
|
| 1438195_at |
Gpd1l |
glycerol-3-phosphate dehydrogenase 1-like |
9 |
-114899338 |
BB727537 |
333433 |
22 |
regulation of heart rate cytoplasm cytosol plasma membrane carbohydrate metabolic process glycerol-3-phosphate metabolic process NADH metabolic process glycerol-3-phosphate dehydrogenase complex positive regulation of sodium ion transport membrane oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor sodium channel regulator activity NAD metabolic process negative regulation of peptidyl-serine phosphorylation protein homodimerization activity transmembrane transporter binding glycerol-3-phosphate catabolic process glycerol-3-phosphate dehydrogenase [NAD(P)+] activity NAD binding regulation of ventricular cardiac muscle cell membrane depolarization ventricular cardiac muscle cell action potential negative regulation of protein kinase C signaling positive regulation of protein localization to cell surface regulation of sodium ion transmembrane transporter activity |
00564 |
| 1434394_at |
N4bp2 |
NEDD4 binding protein 2 |
5 |
65763520 |
AV116077 |
333789 |
20 |
endonuclease activity endonuclease activity DNA endonuclease activity protein binding ATP binding cytosol ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity |
|
| 1435463_s_at |
Myo1d |
myosin ID |
11 |
-80482126 |
C76327 |
338367 |
37 |
microfilament motor activity microfilament motor activity nucleotide binding cytoskeletal motor activity actin binding protein binding calmodulin binding ATP binding cytoplasm cytoplasm endosome plasma membrane plasma membrane microvillus brush border brush border endocytosis actin filament organization protein transport actin cytoskeleton membrane basolateral plasma membrane myosin complex protein domain specific binding actin filament-based movement axon axolemma cytoplasmic vesicle cell projection neuron projection neuronal cell body neuronal cell body myelin sheath myelin sheath myelin sheath plasma membrane raft calcium-dependent protein binding actin filament binding actin filament binding cellular localization apical dendrite |
|
| 1435432_at |
Agap1 |
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
1 |
89454810 |
BE688580 |
347722 |
33 |
nucleotide binding GTPase activity GTPase activity GTPase activator activity GTPase activator activity GTP binding phospholipid binding cytoplasm cytosol protein transport metal ion binding activation of GTPase activity |
04144 |
| 1434681_at |
Txlng |
taxilin gamma |
X |
-162778916, -162788789 |
BG069603 |
353170 |
26 |
protein binding nucleus cytoplasm cytosol cell cycle regulation of cell cycle process membrane syntaxin binding regulation of bone mineralization nuclear membrane nuclear membrane regulation of cell cycle regulation of cell cycle DNA-binding transcription factor binding |
|
| 1416958_at |
Nr1d2 |
nuclear receptor subfamily 1, group D, member 2 |
14 |
-18204055 |
NM_011584 |
353187 |
72 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nuclear receptor activity nuclear receptor activity protein binding nucleus nucleus nucleoplasm cytoplasm regulation of DNA-templated transcription zinc ion binding hormone-mediated signaling pathway regulation of lipid metabolic process cell differentiation regulation of circadian rhythm regulation of circadian rhythm sequence-specific DNA binding negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II metal ion binding rhythmic process circadian behavior regulation of inflammatory response negative regulation of inflammatory response lipid homeostasis energy homeostasis sequence-specific double-stranded DNA binding regulation of skeletal muscle cell differentiation |
|
| 1444090_at |
Pram1 |
PML-RAR alpha-regulated adaptor molecule 1 |
17 |
33638094, 33638055 |
AI561611 |
378460 |
18 |
plasma membrane plasma membrane integrin-mediated signaling pathway integrin-mediated signaling pathway lipid binding protein kinase binding protein-containing complex regulation of neutrophil degranulation T cell receptor signaling pathway protein localization to plasma membrane |
|
| 1431997_at |
3000002C10Rik |
glyceraldehyde-3-phosphate dehydrogenase pseudogene |
9 |
-109830153 |
AK013857 |
378954 |
11 |
|
|
| 1445687_at |
Milr1 |
mast cell immunoglobulin like receptor 1 |
11 |
106751225, 106751225 |
BE629676 |
380732 |
20 |
protein binding extracellular region plasma membrane membrane negative regulation of mast cell activation mast cell degranulation |
|
| 1428279_a_at |
Atxn7l1 |
ataxin 7-like 1 |
12 |
33147685, 33302514, 33315404, 33314296, 33146970, 33146967 |
AK013145 |
380753 |
16 |
molecular_function cellular_component biological_process |
|
| 1455530_at |
Ighd |
immunoglobulin heavy constant delta |
12 |
|
BE686052 |
380797 |
34 |
antigen binding antigen binding external side of plasma membrane immunoglobulin mediated immune response immunoglobulin mediated immune response somatic hypermutation of immunoglobulin genes B cell receptor complex positive regulation of B cell proliferation positive regulation of interleukin-1 production B cell proliferation regulation of immune response regulation of immune response |
|
| 1437060_at |
Olfm4 |
olfactomedin 4 |
14 |
80000301 |
AV290148 |
380924 |
51 |
structural molecule activity protein binding extracellular region extracellular space extracellular space extracellular space nucleoplasm mitochondrion cytosol plasma membrane immune response cell adhesion signal transduction protein-containing complex specific granule negative regulation of canonical NF-kappaB signal transduction intercellular bridge cadherin binding perinuclear region of cytoplasm negative regulation of immune response positive regulation of substrate adhesion-dependent cell spreading |
|
| 1435550_at |
Kmt2d |
lysine (K)-specific methyltransferase 2D |
15 |
-98831668 |
BB702910 |
381022 |
100 |
transcription cis-regulatory region binding DNA-binding transcription activator activity, RNA polymerase II-specific oocyte growth in utero embryonic development transcription coactivator activity protein binding nucleus nucleoplasm chromatin organization methyltransferase activity positive regulation of cell population proliferation regulation of gene expression transferase activity heterochromatin formation methylation positive regulation of intracellular estrogen receptor signaling pathway histone methyltransferase complex histone binding histone H3K4 methyltransferase activity histone H3K4 methyltransferase activity response to estrogen MLL3/4 complex MLL3/4 complex positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding oogenesis histone H3K4 monomethyltransferase activity |
|
| 1456792_at |
Tbc1d2 |
TBC1 domain family, member 2 |
4 |
-46604389 |
BG967046 |
381605 |
17 |
GTPase activator activity GTPase activator activity nucleoplasm cytoplasm cytosol plasma membrane cell junction cytoplasmic vesicle positive regulation of GTPase activity cadherin binding anchoring junction activation of GTPase activity |
|
| 1435391_at |
Rbm33 |
RNA binding motif protein 33 |
5 |
28317188 |
BM236842 |
381626 |
23 |
molecular_function nucleic acid binding RNA binding RNA binding cellular_component nucleus cytoplasm RNA export from nucleus biological_process protein-macromolecule adaptor activity oxidative single-stranded RNA demethylation regulation of mRNA stability lncRNA binding N6-methyladenosine-containing RNA reader activity |
|
| 1428492_at |
Glipr2 |
GLI pathogenesis-related 2 |
4 |
43957701 |
BM208214 |
384009 |
26 |
Golgi membrane extracellular region extracellular space Golgi apparatus positive regulation of epithelial cell migration positive regulation of epithelial to mesenchymal transition membrane protein homodimerization activity positive regulation of ERK1 and ERK2 cascade |
|
| 1436941_at |
Nxpe3 |
neurexophilin and PC-esterase domain family, member 3 |
16 |
-55839952 |
BB626288 |
385658 |
11 |
molecular_function cellular_component biological_process |
|
| 1455291_s_at |
Znrf2 |
zinc and ring finger 2 |
6 |
54816915 |
BG071922 |
387524 |
20 |
fibrillar center nucleoplasm cytoplasm cytoplasm lysosome endosome plasma membrane membrane membrane transferase activity cytoplasmic vesicle membrane protein-containing complex cell projection proteasome-mediated ubiquitin-dependent protein catabolic process intracellular membrane-bounded organelle intracellular membrane-bounded organelle synapse metal ion binding ubiquitin protein ligase activity ubiquitin protein ligase activity protein K48-linked ubiquitination |
|
| 1434301_at |
Lratd2 |
LRAT domain containing 1 |
15 |
-60818995 |
BE303700 |
399603 |
17 |
molecular_function cytoplasm plasma membrane biological_process |
|
| 1435754_at |
Zyg11b |
zyg-ll family member B, cell cycle regulator |
4 |
-108227754 |
BQ180736 |
414872 |
17 |
protein quality control for misfolded or incompletely synthesized proteins Cul2-RING ubiquitin ligase complex Cul2-RING ubiquitin ligase complex positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
|
| 1428231_at |
Cpsf6 |
cleavage and polyadenylation specific factor 6 |
10 |
-117344667, -117344666 |
BB425379 |
432508 |
43 |
nucleic acid binding RNA binding mRNA binding mRNA binding protein binding nucleus nucleus nucleoplasm perichromatin fibrils cytoplasm mRNA cleavage and polyadenylation specificity factor complex mRNA cleavage and polyadenylation specificity factor complex mRNA cleavage factor complex mRNA processing nuclear speck mRNA 3'-end processing interchromatin granule paraspeckles ribosomal large subunit binding positive regulation of RNA export from nucleus localization protein tetramerization protein heterotetramerization mRNA alternative polyadenylation mRNA alternative polyadenylation messenger ribonucleoprotein complex assembly exon-exon junction complex binding ribonucleoprotein complex |
03015 |
| 1457285_at |
Zscan26 |
zinc finger and SCAN domain containing 26 |
13 |
-21442180 |
BB354728 |
432731 |
14 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus nucleoplasm cytosol regulation of transcription by RNA polymerase II metal ion binding |
|
| 1455324_at |
Plcxd2 |
phosphatidylinositol-specific phospholipase C, X domain containing 2 |
16 |
-45959260 |
BQ176176 |
433022 |
16 |
molecular_function cellular_component nucleus lipid metabolic process signal transduction phosphoric diester hydrolase activity phosphoric diester hydrolase activity biological_process lipid catabolic process hydrolase activity |
|
| 1434046_at |
AA467197 |
expressed sequence AA467197 |
2 |
122637886 |
BG961961 |
433470 |
18 |
nucleus mitochondrion mitochondrial respiratory chain complex IV response to bacterium |
|
| 1455518_at |
Zdhhc18 |
zinc finger, DHHC domain containing 18 |
4 |
-133606991 |
BB324402 |
503610 |
18 |
immune system process endoplasmic reticulum Golgi apparatus Golgi apparatus protein targeting to membrane protein localization membrane palmitoyltransferase activity palmitoyltransferase activity transferase activity acyltransferase activity peptidyl-L-cysteine S-palmitoylation peptidyl-L-cysteine S-palmitoylation protein palmitoylation protein-cysteine S-palmitoyltransferase activity protein-cysteine S-palmitoyltransferase activity innate immune response negative regulation of innate immune response negative regulation of cGAS/STING signaling pathway |
|
| 1449222_at |
Ebi3 |
Epstein-Barr virus induced gene 3 |
17 |
55952622 |
NM_015766 |
50498 |
106 |
cytokine receptor activity cytokine receptor activity cytokine activity protein binding extracellular region extracellular space external side of plasma membrane membrane cytokine-mediated signaling pathway cytokine binding T cell proliferation receptor complex interleukin-27 receptor binding |
|
| 1419681_a_at |
Prok2 |
prokineticin 2 |
6 |
-99711298 |
NM_015768 |
50501 |
66 |
angiogenesis G protein-coupled receptor binding G protein-coupled receptor binding endothelial cell proliferation endothelial cell proliferation epicardium-derived cardiac endothelial cell differentiation extracellular region chemotaxis neuropeptide signaling pathway spermatogenesis circadian rhythm negative regulation of apoptotic process positive regulation of smooth muscle contraction rhythmic process coronary vasculature development vasculogenesis involved in coronary vascular morphogenesis epicardium-derived cardiac vascular smooth muscle cell differentiation |
|
| 1434958_at |
Sacs |
sacsin |
14 |
61138456, 61138456 |
BG075163 |
50720 |
30 |
nucleus cytoplasm mitochondrion Hsp70 protein binding Hsp70 protein binding identical protein binding low-density lipoprotein particle receptor binding protein-folding chaperone binding proteasome binding negative regulation of inclusion body assembly |
|
| 1419212_at |
Icosl |
icos ligand |
10 |
78069367 |
NM_015790 |
50723 |
119 |
regulation of cytokine production adaptive immune response immune system process signaling receptor binding signaling receptor binding protein binding plasma membrane plasma membrane signal transduction external side of plasma membrane external side of plasma membrane membrane positive regulation of interleukin-4 production positive regulation of activated T cell proliferation T cell activation B cell activation identical protein binding intracellular membrane-bounded organelle isotype switching T cell receptor signaling pathway |
04514 04672 |
| 1456388_at |
Atp11a |
ATPase, class VI, type 11A |
8 |
12757015 |
AV378604 |
50770 |
36 |
nucleotide binding magnesium ion binding in utero embryonic development transporter activity ATP binding endosome endoplasmic reticulum endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane lipid transport positive regulation of myotube differentiation positive regulation of myotube differentiation phospholipid transport membrane ATP hydrolysis activity intracellular membrane-bounded organelle phospholipid translocation metal ion binding recycling endosome recycling endosome phosphatidylethanolamine flippase activity regulation of membrane lipid distribution ATPase-coupled intramembrane lipid transporter activity ATPase-coupled intramembrane lipid transporter activity phosphatidylserine flippase activity phospholipid-translocating ATPase complex |
|
| 1417009_at |
C1ra |
complement component 1, r subcomponent A |
6 |
124512620 |
NM_023143 |
50909 |
22 |
immune system process serine-type endopeptidase activity serine-type endopeptidase activity calcium ion binding extracellular region extracellular space extracellular space proteolysis complement activation complement activation, classical pathway peptidase activity serine-type peptidase activity hydrolase activity zymogen activation zymogen activation identical protein binding innate immune response molecular sequestering activity |
04145 04610 05150 05322 |
| 1456698_s_at |
Hnrnpdl |
heterogeneous nuclear ribonucleoprotein D-like |
5 |
-100033578 |
BB711246 |
50926 |
41 |
nucleic acid binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm poly(A) binding poly(A) binding regulation of gene expression regulation of gene expression mRNA metabolic process poly(G) binding poly(G) binding synapse synapse |
|
| 1449508_at |
Il27ra |
interleukin 27 receptor, alpha |
8 |
-84030285 |
NM_016671 |
50931 |
162 |
negative regulation of cellular extravasation positive regulation of T-helper 1 type immune response negative regulation of type 2 immune response protein binding extracellular region cytoplasm plasma membrane external side of plasma membrane membrane cytokine-mediated signaling pathway cytokine binding negative regulation of interleukin-17 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of type II interferon production receptor complex negative regulation of neuron apoptotic process interleukin-27 receptor activity interleukin-27 receptor activity regulation of isotype switching to IgG isotypes defense response to Gram-positive bacterium negative regulation of T-helper 17 type immune response negative regulation of T cell extravasation |
|
| 1434390_at |
Hnrnpu |
heterogeneous nuclear ribonucleoprotein U |
1 |
-178326733, -178321107 |
BB200448 |
51810 |
88 |
negative regulation of transcription by RNA polymerase II nucleotide binding nuclear chromosome alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome chromosome, centromeric region kinetochore RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II complex binding TFIIH-class transcription factor complex binding DNA binding chromatin binding double-stranded DNA binding single-stranded DNA binding transcription corepressor activity RNA binding RNA binding RNA binding RNA binding double-stranded RNA binding single-stranded RNA binding mRNA 3'-UTR binding actin binding protein binding ATP binding nucleus nucleus nucleus nucleoplasm spliceosomal complex chromosome telomerase holoenzyme complex cytoplasm centrosome cytosol cytoskeleton chromatin organization mRNA processing cell cycle multicellular organism development regulation of mitotic cell cycle poly(A) binding RNA splicing dosage compensation by inactivation of X chromosome cell surface positive regulation of gene expression mRNA metabolic process nuclear matrix nuclear speck snRNA binding poly(C) RNA binding cell differentiation dendrite midbody chromatin DNA binding negative regulation of telomere maintenance via telomerase dendrite cytoplasm circadian regulation of gene expression protein-containing complex negative regulation of kinase activity poly(G) binding negative regulation of transcription elongation by RNA polymerase II pre-mRNA binding cytoplasmic ribonucleoprotein granule identical protein binding ribonucleoprotein complex binding sequence-specific DNA binding protein-containing complex binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II mRNA stabilization rhythmic process cell division maintenance of protein location in nucleus cardiac muscle cell development telomerase RNA binding CRD-mediated mRNA stabilization CRD-mediated mRNA stability complex catalytic step 2 spliceosome cellular response to glucocorticoid stimulus cellular response to dexamethasone stimulus mitotic spindle positive regulation of brown fat cell differentiation RNA polymerase II transcription regulator complex inactive sex chromosome inactive sex chromosome dendritic transport of messenger ribonucleoprotein complex dendritic transport of messenger ribonucleoprotein complex RNA polymerase II C-terminal domain binding lncRNA binding negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay regulation of mitotic spindle assembly regulation of chromatin organization positive regulation of attachment of mitotic spindle microtubules to kinetochore protein localization to spindle microtubule mitotic spindle midzone RNA localization to chromatin mitotic spindle microtubule cellular response to leukemia inhibitory factor sequence-specific double-stranded DNA binding promoter-specific chromatin binding promoter-specific chromatin binding promoter-specific chromatin binding adaptive thermogenesis ribonucleoprotein complex ribonucleoprotein complex ribonucleoprotein complex positive regulation of stem cell proliferation negative regulation of stem cell differentiation negative regulation of stem cell differentiation positive regulation of cytoplasmic translation |
03040 |
| 1433640_at |
Fubp1 |
far upstream element (FUSE) binding protein 1 |
3 |
152210421 |
BG070740 |
51886 |
55 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding nucleic acid binding DNA binding RNA binding mRNA binding protein binding nucleus nucleus nucleoplasm cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of gene expression positive regulation of gene expression synapse synapse somatic stem cell division developmental cell growth hematopoietic stem cell proliferation positive regulation of Schwann cell migration |
|
| 1453239_a_at |
Ankrd22 |
ankyrin repeat domain 22 |
19 |
-34122548 |
AK012869 |
52024 |
15 |
molecular_function cellular_component biological_process |
|
| 1429005_at |
Mfhas1 |
malignant fibrous histiocytoma amplified sequence 1 |
8 |
35587788 |
BB107412 |
52065 |
18 |
nucleotide binding immune system process GTP binding cytoplasm defense response inflammatory response inflammatory response signal transduction negative regulation of signal transduction erythrocyte differentiation ubiquitin protein ligase binding regulation of toll-like receptor signaling pathway negative regulation of toll-like receptor 2 signaling pathway negative regulation of toll-like receptor 2 signaling pathway positive regulation of toll-like receptor 2 signaling pathway positive regulation of toll-like receptor 2 signaling pathway negative regulation of toll-like receptor 4 signaling pathway negative regulation of protein dephosphorylation regulation of macrophage activation innate immune response innate immune response positive regulation of JNK cascade negative regulation of inflammatory response protein phosphatase 2A binding positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of ERK1 and ERK2 cascade negative regulation of protein localization to nucleus positive regulation of p38MAPK cascade |
|
| 1435342_at |
Kcnk6 |
potassium inwardly-rectifying channel, subfamily K, member 6 |
7 |
-29221927 |
BG069589 |
52150 |
21 |
regulation of systemic arterial blood pressure negative regulation of systemic arterial blood pressure potassium channel activity plasma membrane outward rectifier potassium channel activity potassium ion leak channel activity stabilization of membrane potential regulation of resting membrane potential potassium ion transmembrane transport |
|
| 1438000_x_at |
Zfp622 |
zinc finger protein 622 |
15 |
25984365 |
BB026724 |
52521 |
21 |
nucleic acid binding nucleus nucleoplasm nucleolus cytoplasm Golgi apparatus cytosol zinc ion binding intrinsic apoptotic signaling pathway in response to oxidative stress preribosome, large subunit precursor positive regulation of kinase activity ribosome biogenesis ribosomal large subunit biogenesis ribosomal large subunit biogenesis positive regulation of apoptotic process positive regulation of MAPK cascade positive regulation of JNK cascade metal ion binding preribosome binding |
|
| 1419985_s_at |
Ccdc69 |
coiled-coil domain containing 69 |
11 |
-55049737 |
C87579 |
52570 |
14 |
nucleus cytoplasm cytoplasm cytoskeleton microtubule binding spindle midzone spindle midzone assembly |
|
| 1424333_at |
Trmt10c |
tRNA methyltransferase 10C, mitochondrial RNase P subunit |
16 |
-56033719 |
BC023147 |
52575 |
26 |
tRNA binding tRNA binding mitochondrial RNA 5'-end processing nucleus nucleoplasm nucleoplasm mitochondrion mitochondrion mitochondrion mitochondrion tRNA processing methyltransferase activity transferase activity mitochondrial ribonuclease P complex methylation mitochondrial nucleoid identical protein binding tRNA methyltransferase complex tRNA (guanosine(9)-N1)-methyltransferase activity positive regulation of mitochondrial translation positive regulation of mitochondrial translation mitochondrial tRNA methylation mRNA methylation mitochondrial tRNA processing mitochondrial tRNA 5'-end processing mitochondrial tRNA 5'-end processing tRNA (adenine(9)-N1)-methyltransferase activity mitochondrial tRNA 3'-end processing |
|
| 1433557_at |
Cbx7 |
chromobox 7 |
15 |
-79915806 |
AV024881 |
52609 |
60 |
negative regulation of transcription by RNA polymerase II chromatin heterochromatin chromatin binding RNA binding single-stranded RNA binding protein binding nucleus nucleus nucleoplasm chromosome cytosol chromatin organization PcG protein complex positive regulation of transcription elongation by RNA polymerase II methylated histone binding PRC1 complex sebaceous gland development |
|
| 1430447_a_at |
Lair1 |
leukocyte-associated Ig-like receptor 1 |
7 |
-4007072 |
AK017222 |
52855 |
32 |
plasma membrane plasma membrane membrane |
|
| 1416708_a_at |
Gramd1a |
GRAM domain containing 1A |
7 |
-31130126 |
NM_027898 |
52857 |
25 |
endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane cytosol plasma membrane plasma membrane plasma membrane lipid transport autophagy lipid binding cholesterol binding cholesterol binding membrane cytoplasmic vesicle intracellular sterol transport organelle membrane contact site cellular response to cholesterol cholesterol transfer activity cholesterol transfer activity endoplasmic reticulum-plasma membrane contact site endoplasmic reticulum-plasma membrane contact site |
|
| 1417168_a_at |
Usp2 |
ubiquitin specific peptidase 2 |
9 |
44069428, 44084919, 44067020 |
AI553394 |
53376 |
50 |
negative regulation of transcription by RNA polymerase II cysteine-type deubiquitinase activity protein binding nucleus cytoplasm cytoplasm centrosome proteolysis cell cycle muscle organ development peptidase activity cysteine-type peptidase activity membrane protein deubiquitination protein deubiquitination hydrolase activity cyclin binding ubiquitin protein ligase binding circadian regulation of gene expression identical protein binding entrainment of circadian clock by photoperiod locomotor rhythm positive regulation of mitotic cell cycle metal ion binding perinuclear region of cytoplasm rhythmic process circadian behavior negative regulation of skeletal muscle tissue development positive regulation of skeletal muscle tissue development protein stabilization negative regulation of calcium ion transport |
|
| 1420477_at |
Nap1l1 |
nucleosome assembly protein 1-like 1 |
10 |
111473226 |
BG064031 |
53605 |
48 |
chromatin chromatin binding protein binding nucleus nucleus cytoplasm nucleosome assembly nucleosome assembly nervous system development kinase binding histone binding positive regulation of neurogenesis histone chaperone activity positive regulation of neural precursor cell proliferation |
|
| 1450784_at |
Reck |
reversion-inducing-cysteine-rich protein with kazal motifs |
4 |
43875529 |
NM_016678 |
53614 |
66 |
blood vessel maturation blood vessel maturation blood vessel maturation sprouting angiogenesis endopeptidase inhibitor activity endopeptidase inhibitor activity endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity protein binding plasma membrane plasma membrane plasma membrane embryo implantation metalloendopeptidase inhibitor activity negative regulation of peptidase activity coreceptor activity membrane Wnt signaling pathway Wnt-protein binding extracellular matrix organization extracellular matrix organization negative regulation of cell migration peptidase inhibitor activity embryonic forelimb morphogenesis positive regulation of Notch signaling pathway regulation of angiogenesis canonical Wnt signaling pathway regulation of establishment of blood-brain barrier positive regulation of canonical Wnt signaling pathway side of membrane negative regulation of metalloendopeptidase activity negative regulation of metalloendopeptidase activity negative regulation of metalloendopeptidase activity Wnt signalosome |
|
| 1448221_at |
Ddx39b |
DEAD box helicase 39b |
17 |
35241745, 35242816 |
BC011067 |
53817 |
44 |
nucleotide binding spliceosomal complex assembly transcription export complex mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding RNA helicase activity RNA helicase activity mRNA binding helicase activity ATP binding nucleus spliceosomal complex U4 snRNP U6 snRNP cytoplasm mRNA processing mRNA export from nucleus mRNA export from nucleus ATP-dependent activity, acting on RNA RNA splicing RNA secondary structure unwinding nuclear matrix nuclear speck nuclear speck hydrolase activity ATP hydrolysis activity U6 snRNA binding U4 snRNA binding protein-containing complex identical protein binding ATP-dependent protein binding protein-containing complex binding positive regulation of translation mRNA transport positive regulation of cell growth involved in cardiac muscle cell development positive regulation of vascular associated smooth muscle cell proliferation positive regulation of DNA biosynthetic process |
03013 03015 03040 |
| 1423103_at |
Rfx5 |
regulatory factor X, 5 (influences HLA class II expression) |
3 |
94954107, 94954515 |
BB392192 |
53970 |
32 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II intracellular membrane-bounded organelle sequence-specific DNA binding positive regulation of transcription by RNA polymerase II RNA polymerase II transcription regulator complex sequence-specific double-stranded DNA binding |
04612 05340 |
| 1427564_at |
Diaph2 |
diaphanous related formin 2 |
X |
129749741 |
Y15910 |
54004 |
41 |
actin binding protein binding nucleolus endoplasmic reticulum actin filament multicellular organism development protein localization cellular component organization axon midline choice point recognition actin cytoskeleton organization actin filament polymerization actin filament polymerization cell differentiation small GTPase binding intracellular membrane-bounded organelle ephrin receptor signaling pathway oogenesis negative regulation of neuron projection regeneration multicellular organismal locomotion neuron projection retraction |
04810 |
| 1417244_a_at |
Irf7 |
interferon regulatory factor 7 |
7 |
-141263182 |
NM_016850 |
54123 |
270 |
chromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding immune system process immune system process cytoplasmic pattern recognition receptor signaling pathway regulation of adaptive immune response DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm cytoplasm cytosol regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of gene expression immunoglobulin mediated immune response positive regulation of type I interferon production positive regulation of type I interferon production positive regulation of type I interferon production type I interferon production positive regulation of interferon-alpha production positive regulation of interferon-alpha production positive regulation of interferon-beta production positive regulation of interferon-beta production regulation of MyD88-dependent toll-like receptor signaling pathway regulation of MyD88-independent toll-like receptor signaling pathway innate immune response regulation of innate immune response positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II defense response to virus defense response to virus type I interferon-mediated signaling pathway positive regulation of type I interferon-mediated signaling pathway sequence-specific double-stranded DNA binding |
04620 04622 04623 05160 |
| 1439953_at |
Pmm2 |
phosphomannomutase 2 |
16 |
8637706 |
BB709170 |
54128 |
28 |
phosphomannomutase activity phosphomannomutase activity nucleoplasm cytoplasm cytosol cytosol mannose metabolic process protein N-linked glycosylation GDP-mannose biosynthetic process isomerase activity neuronal cell body metal ion binding |
00051 00520 01100 |
| 1422576_at |
Atxn10 |
ataxin 10 |
15 |
85336254 |
NM_016843 |
54138 |
42 |
protein binding cytoplasm cytosol cytosol plasma membrane nervous system development enzyme binding dendrite neuron projection development neuron projection development identical protein binding neuronal cell body perinuclear region of cytoplasm cilium assembly |
|
| 1418301_at |
Irf6 |
interferon regulatory factor 6 |
1 |
193153111 |
NM_016851 |
54139 |
93 |
transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific immune system process DNA binding DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II cell population proliferation negative regulation of cell population proliferation negative regulation of keratinocyte proliferation cell differentiation keratinocyte differentiation sequence-specific DNA binding skin development skin development keratinocyte proliferation keratinocyte proliferation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II cell development roof of mouth development limb development mammary gland epithelial cell differentiation stem cell proliferation cranial skeletal system development sequence-specific double-stranded DNA binding negative regulation of stem cell proliferation |
|
| 1436598_at |
Icos |
inducible T cell co-stimulator |
1 |
60977913 |
AV313923 |
54167 |
224 |
T cell tolerance induction T cell tolerance induction protein binding plasma membrane external side of plasma membrane membrane T cell costimulation T cell costimulation cell-cell adhesion cell-cell adhesion |
04514 04660 04672 05340 |
| 1422850_at |
Pabpn1 |
poly(A) binding protein, nuclear 1 |
14 |
54894142 |
AV028400 |
54196 |
55 |
MAPK cascade nucleic acid binding RNA binding protein binding nucleus nucleus nucleus cytoplasm cytosol mRNA processing poly(A) binding poly(A) binding poly(A)+ mRNA export from nucleus regulation of mRNA 3'-end processing nuclear inclusion body protein self-association RNA polymerase binding cellular response to lipopolysaccharide positive regulation of polynucleotide adenylyltransferase activity ribonucleoprotein complex ribonucleoprotein complex |
03015 |
| 1427736_a_at |
Ccrl2 |
C-C motif chemokine receptor-like 2 |
9 |
-111054833, -111054833, -111054833 |
AJ318863 |
54199 |
39 |
G protein-coupled receptor activity chemokine receptor activity cytoplasm plasma membrane chemotaxis inflammatory response inflammatory response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration external side of plasma membrane membrane C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding chemokine receptor binding chemokine receptor binding CCR chemokine receptor binding cell chemotaxis chemokine-mediated signaling pathway |
|
| 1416441_at |
Cpq |
carboxypeptidase Q |
15 |
33083128 |
BB468025 |
54381 |
16 |
carboxypeptidase activity extracellular region extracellular space extracellular space extracellular space cytoplasm lysosome lysosome endoplasmic reticulum Golgi apparatus proteolysis proteolysis thyroid hormone generation thyroid hormone generation peptidase activity metallopeptidase activity hydrolase activity protein homodimerization activity peptide catabolic process peptide catabolic process intracellular membrane-bounded organelle metal ion binding metallodipeptidase activity metallodipeptidase activity |
|
| 1417793_at |
Irgm2 |
immunity-related GTPase family M member 2 |
11 |
58214976 |
NM_019440 |
54396 |
27 |
autophagosome assembly Golgi membrane Golgi membrane nucleotide binding autophagosome membrane positive regulation of protein phosphorylation immune system process GTPase activity GTPase activity GTPase activity GTPase activity G protein activity GTP binding cytoplasm mitochondrion vacuolar membrane endoplasmic reticulum membrane Golgi apparatus cytosol cytosol defense response response to bacterium positive regulation of autophagy positive regulation of peptidyl-threonine phosphorylation membrane hydrolase activity protein kinase binding protein-macromolecule adaptor activity cytoplasmic vesicle killing of cells of another organism protein destabilization negative regulation of type I interferon production positive regulation of peptidyl-serine phosphorylation cellular response to interferon-beta defense response to bacterium defense response to protozoan negative regulation of canonical NF-kappaB signal transduction regulation of protein-containing complex assembly protein serine/threonine kinase activator activity protein targeting to vacuolar membrane innate immune response negative regulation of defense response to virus CARD domain binding negative regulation of inflammatory response protein stabilization defense response to Gram-negative bacterium BH3 domain binding positive regulation of type II interferon-mediated signaling pathway regulation of protein complex stability protein lipidation involved in autophagosome assembly CAMKK-AMPK signaling cascade protein-containing complex assembly nucleotide-binding oligomerization domain containing 2 signaling pathway protein targeting to vacuole involved in autophagy cellular response to lipopolysaccharide positive regulation of protein serine/threonine kinase activity positive regulation of mitochondrial fission cellular response to virus negative regulation of cGAS/STING signaling pathway negative regulation of non-canonical inflammasome complex assembly negative regulation of NLRP3 inflammasome complex assembly positive regulation of autophagosome maturation positive regulation of mitophagy cardiolipin binding positive regulation of xenophagy positive regulation of lysosome organization |
|
| 1460283_at |
Mefv |
Mediterranean fever |
16 |
-3707214 |
NM_019453 |
54483 |
37 |
pattern recognition receptor signaling pathway immune system process actin binding nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytosol cytosol cytoskeleton microtubule microtubule associated complex inflammatory response zinc ion binding regulation of gene expression positive regulation of autophagy protein ubiquitination cytoplasmic vesicle regulation of interleukin-1 beta production negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 beta production response to type II interferon identical protein binding cell projection innate immune response innate immune response metal ion binding negative regulation of inflammatory response positive regulation of inflammatory response ubiquitin protein ligase activity canonical inflammasome complex pyroptosis negative regulation of macrophage inflammatory protein 1 alpha production negative regulation of cytokine production involved in inflammatory response negative regulation of NLRP3 inflammasome complex assembly pyroptosome complex assembly positive regulation of cysteine-type endopeptidase activity |
04621 |
| 1425814_a_at |
Calcrl |
calcitonin receptor-like |
2 |
-84330626 |
AF209905 |
54598 |
47 |
angiogenesis angiogenesis adrenomedullin receptor activity adrenomedullin receptor activity calcitonin gene-related peptide receptor activity calcitonin gene-related peptide receptor activity calcitonin gene-related peptide receptor activity transmembrane signaling receptor activity G protein-coupled receptor activity calcitonin receptor activity cytoplasm lysosome endosome endoplasmic reticulum plasma membrane plasma membrane calcium ion transport signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway heart development cell population proliferation positive regulation of cell population proliferation protein transport membrane receptor internalization negative regulation of smooth muscle contraction smooth muscle cell proliferation cellular response to sucrose stimulus neuronal dense core vesicle adrenomedullin receptor complex positive regulation of vascular associated smooth muscle cell proliferation CGRP receptor complex calcitonin gene-related peptide receptor signaling pathway adrenomedullin binding adrenomedullin receptor signaling pathway adrenomedullin receptor signaling pathway vascular associated smooth muscle cell proliferation |
04080 04270 |
| 1416996_at |
Tbc1d8 |
TBC1 domain family, member 8 |
1 |
-39371495, -39371495, -39373312 |
BC005421 |
54610 |
19 |
GTPase activator activity GTPase activator activity activation of GTPase activity |
|
| 1417894_at |
Adgrg3 |
adhesion G protein-coupled receptor G3 |
8 |
95017691 |
NM_025309 |
54672 |
22 |
transmembrane signaling receptor activity G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway membrane B cell differentiation regulation of cell migration negative regulation of CREB transcription factor activity negative regulation of non-canonical NF-kappaB signal transduction |
|
| 1416381_a_at |
Prdx5 |
peroxiredoxin 5 |
19 |
-6906696 |
BC008174 |
54683 |
73 |
RNA polymerase III transcription regulatory region sequence-specific DNA binding peroxidase activity signaling receptor binding signaling receptor binding protein binding nucleus cytoplasm cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion peroxisome peroxisome peroxisomal matrix peroxisomal matrix cytosol response to oxidative stress response to oxidative stress thioredoxin peroxidase activity thioredoxin peroxidase activity antioxidant activity antioxidant activity negative regulation of transcription by RNA polymerase III oxidoreductase activity cytoplasmic vesicle positive regulation of collagen biosynthetic process cellular response to oxidative stress cellular response to oxidative stress cellular response to reactive oxygen species hydrogen peroxide catabolic process hydrogen peroxide catabolic process hydrogen peroxide catabolic process identical protein binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process intracellular membrane-bounded organelle cell redox homeostasis perinuclear region of cytoplasm negative regulation of oxidoreductase activity regulation of apoptosis involved in tissue homeostasis NADPH oxidation peroxynitrite reductase activity thioredoxin-dependent peroxiredoxin activity reactive nitrogen species metabolic process |
04146 |
| 1433977_at |
Hs3st3b1 |
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 |
11 |
-63884692 |
BG918344 |
54710 |
28 |
branching involved in ureteric bud morphogenesis Golgi apparatus plasma membrane glycosaminoglycan biosynthetic process protein sulfation sulfotransferase activity [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity heparan sulfate proteoglycan biosynthetic process membrane transferase activity [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity |
00534 |
| 1451564_at |
Parp14 |
poly (ADP-ribose) polymerase family, member 14 |
16 |
-35832877 |
BC021340 |
547253 |
33 |
immune system process transcription corepressor activity NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity protein binding nucleus nucleus cytoplasm cytoplasm cytoplasm cytosol plasma membrane negative regulation of gene expression negative regulation of gene expression transferase activity glycosyltransferase activity nucleotidyltransferase activity enzyme binding positive regulation of tyrosine phosphorylation of STAT protein negative regulation of tyrosine phosphorylation of STAT protein innate immune response negative regulation of type II interferon-mediated signaling pathway negative regulation of type II interferon-mediated signaling pathway protein poly-ADP-ribosylation protein poly-ADP-ribosylation NAD+ binding positive regulation of interleukin-4-mediated signaling pathway positive regulation of interleukin-4-mediated signaling pathway NAD+-protein ADP-ribosyltransferase activity NAD+-protein ADP-ribosyltransferase activity |
|
| 1418392_a_at |
Gbp3 |
guanylate binding protein 3 |
3 |
142560355, 142560043 |
NM_018734 |
55932 |
28 |
nucleotide binding activation of innate immune response immune system process GTPase activity GTPase activity GTP binding GTP binding nucleus cytoplasm Golgi apparatus cytosol cytosol plasma membrane membrane hydrolase activity symbiont-containing vacuole membrane cytoplasmic vesicle cytoplasmic vesicle cellular response to interferon-beta defense response to bacterium identical protein binding protein homodimerization activity defense response to protozoan defense response to protozoan adhesion of symbiont to host innate immune response perinuclear region of cytoplasm defense response to Gram-positive bacterium defense response to Gram-positive bacterium cytolysis in another organism cellular response to lipopolysaccharide cellular response to type II interferon cellular response to type II interferon cellular response to tumor necrosis factor positive regulation of pyroptosis |
|
| 1423191_at |
Fnbp4 |
formin binding protein 4 |
2 |
90745557 |
AK013152 |
55935 |
27 |
protein binding nucleoplasm biological_process |
|
| 1432195_s_at |
Ccnl2 |
cyclin L2 |
4 |
155812488 |
AK008585 |
56036 |
28 |
cyclin-dependent protein kinase holoenzyme complex protein binding nucleus nucleus nucleoplasm regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cyclin-dependent protein serine/threonine kinase regulator activity cyclin-dependent protein serine/threonine kinase regulator activity regulation of apoptotic process intracellular membrane-bounded organelle regulation of RNA splicing regulation of centrosome cycle regulation of cell cycle |
|
| 1418131_at |
Samhd1 |
SAM domain and HD domain, 1 |
2 |
-157119560, -157097533 |
NM_018851 |
56045 |
51 |
nucleotide binding double-strand break repair via homologous recombination immune system process nucleic acid binding single-stranded DNA binding RNA binding catalytic activity GTP binding nucleus nucleus nucleoplasm chromosome plasma membrane dGTP catabolic process dGTP catabolic process DNA replication DNA repair DNA damage response metabolic process zinc ion binding dGTPase activity dGTPase activity dGTPase activity deoxyribonucleotide catabolic process somatic hypermutation of immunoglobulin genes hydrolase activity triphosphoric monoester hydrolase activity triphosphoric monoester hydrolase activity dGTP binding site of double-strand break identical protein binding innate immune response regulation of innate immune response regulation of innate immune response dATP catabolic process metal ion binding protein homotetramerization protein homotetramerization defense response to virus defense response to virus negative regulation of type I interferon-mediated signaling pathway negative regulation of type I interferon-mediated signaling pathway tetraspanin-enriched microdomain DNA strand resection involved in replication fork processing |
|
| 1434434_s_at |
Tcerg1 |
transcription elongation regulator 1 (CA150) |
18 |
42511486 |
AW557777 |
56070 |
40 |
negative regulation of transcription by RNA polymerase II DNA-binding transcription factor activity transcription coregulator activity transcription coregulator activity transcription corepressor activity nucleus nucleus nucleoplasm DNA-templated transcription regulation of DNA-templated transcription mRNA processing RNA splicing nuclear matrix identical protein binding ubiquitin-like protein conjugating enzyme binding positive regulation of transcription by RNA polymerase II RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase binding RNA polymerase binding proline-rich region binding |
03040 |
| 1436038_a_at |
Pigp |
phosphatidylinositol glycan anchor biosynthesis, class P |
16 |
-94364451, -94364451, -94364451, -94364451, -94358762 |
BF318238 |
56176 |
22 |
glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane GPI anchor biosynthetic process GPI anchor biosynthetic process GPI anchor biosynthetic process membrane phosphatidylinositol N-acetylglucosaminyltransferase activity |
00563 01100 |
| 1417523_at |
Plek |
pleckstrin |
11 |
-16971205 |
AF181829 |
56193 |
19 |
protein kinase C binding cytoplasm plasma membrane vesicle docking involved in exocytosis integrin-mediated signaling pathway positive regulation of platelet activation negative regulation of inositol phosphate biosynthetic process positive regulation of inositol-polyphosphate 5-phosphatase activity cell projection organization actin cytoskeleton organization positive regulation of actin filament depolymerization positive regulation of actin filament depolymerization phospholipase C-inhibiting G protein-coupled receptor signaling pathway cortical actin cytoskeleton organization ruffle organization positive regulation of actin filament bundle assembly ruffle membrane positive regulation of integrin activation intracellular signal transduction protein homodimerization activity phosphatidylinositol-3,4-bisphosphate binding negative regulation of G protein-coupled receptor signaling pathway phosphatidylinositol metabolic process regulation of cell diameter thrombin-activated receptor signaling pathway thrombin-activated receptor signaling pathway platelet aggregation protein kinase C signaling protein secretion by platelet |
|
| 1448706_at |
Tdp2 |
tyrosyl-DNA phosphodiesterase 2 |
13 |
24831658 |
NM_019551 |
56196 |
32 |
magnesium ion binding single-stranded DNA binding single-stranded DNA binding catalytic activity nuclease activity endonuclease activity nucleus nucleoplasm cytoplasm cytoplasm DNA repair double-strand break repair double-strand break repair DNA damage response phosphoric diester hydrolase activity aggresome nuclear body PML body PML body hydrolase activity manganese ion binding tyrosyl-RNA phosphodiesterase activity metal ion binding neuron development 5'-tyrosyl-DNA phosphodiesterase activity 5'-tyrosyl-DNA phosphodiesterase activity |
|
| 1422624_at |
Rev1 |
REV1, DNA directed polymerase |
1 |
-38052785 |
NM_019570 |
56210 |
60 |
DNA binding damaged DNA binding DNA-directed DNA polymerase activity protein binding nucleus DNA repair DNA damage response response to UV transferase activity nucleotidyltransferase activity deoxycytidyl transferase activity deoxycytidyl transferase activity error-prone translesion synthesis error-prone translesion synthesis metal ion binding error-free translesion synthesis DNA biosynthetic process |
|
| 1451146_at |
Zfp386 |
zinc finger protein 386 (Kruppel-like) |
12 |
116047723 |
BC004747 |
56220 |
21 |
negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific chromatin binding double-stranded DNA binding nucleus regulation of transcription by RNA polymerase II |
|
| 1429710_at |
Styx |
serine/threonine/tyrosine interaction protein |
14 |
45351185 |
BB812465 |
56291 |
17 |
pseudophosphatase activity protein binding nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytoplasm spermatogenesis negative regulation of protein binding negative regulation of protein binding MAPK export from nucleus negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process regulation of ERK1 and ERK2 cascade regulation of ERK1 and ERK2 cascade F-box domain binding F-box domain binding |
|
| 1419665_a_at |
Nupr1 |
nuclear protein transcription regulator 1 |
7 |
-126623245 |
NM_019738 |
56312 |
71 |
acute inflammatory response DNA binding chromatin binding transcription coactivator activity protein binding nucleus nucleus nucleoplasm cytoplasm protein acetylation negative regulation of cell population proliferation male gonad development response to toxic substance regulation of autophagy negative regulation of autophagy negative regulation of autophagy negative regulation of cardiac muscle cell apoptotic process acetyltransferase activator activity positive regulation of protein modification process protein-DNA complex skeletal muscle cell differentiation intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of apoptotic process negative regulation of DNA-binding transcription factor activity positive regulation of neuron apoptotic process fibroblast apoptotic process intercellular bridge negative regulation of cell cycle negative regulation of cell cycle negative regulation of cell cycle positive regulation of cell cycle negative regulation of glycolytic process fibroblast proliferation negative regulation of fibroblast proliferation perinuclear region of cytoplasm negative regulation of epithelial cell proliferation negative regulation of programmed necrotic cell death protein-containing complex assembly positive regulation of neuroinflammatory response positive regulation of proteasomal protein catabolic process negative regulation of autophagosome assembly positive regulation of oxidative phosphorylation negative regulation of epithelial cell apoptotic process negative regulation of type B pancreatic cell proliferation regulation of response to endoplasmic reticulum stress regulation of female gonad development positive regulation of fibroblast apoptotic process positive regulation of intrinsic apoptotic signaling pathway |
|
| 1460329_at |
B4galt6 |
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 |
18 |
-20684598 |
BG066773 |
56386 |
29 |
lactosylceramide biosynthetic process Golgi apparatus Golgi apparatus carbohydrate metabolic process lipid metabolic process sphingolipid metabolic process glycosphingolipid biosynthetic process glycosphingolipid biosynthetic process galactosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity ganglioside biosynthetic process via lactosylceramide membrane transferase activity glycosyltransferase activity central nervous system neuron axonogenesis central nervous system myelination sphingolipid biosynthetic process neuron maturation metal ion binding glycosylation |
00600 01100 |
| 1424973_at |
Cyp3a25 |
cytochrome P450, family 3, subfamily a, polypeptide 25 |
5 |
-145977193, -145977193 |
AF204959 |
56388 |
18 |
monooxygenase activity iron ion binding endoplasmic reticulum steroid metabolic process testosterone 16-alpha-hydroxylase activity steroid hydroxylase activity retinoic acid 4-hydroxylase activity response to bacterium membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen heme binding intracellular membrane-bounded organelle metal ion binding testosterone 6-beta-hydroxylase activity testosterone 6-beta-hydroxylase activity aromatase activity oxidative demethylation estrogen 16-alpha-hydroxylase activity estrogen 2-hydroxylase activity |
00140 00591 00830 00980 00982 00983 01100 |
| 1433669_at |
Akap8 |
A kinase anchor protein 8 |
17 |
-32303671 |
BB037566 |
56399 |
50 |
chromatin condensed chromosome condensed chromosome female pronucleus immune system process DNA binding chromatin binding double-stranded DNA binding protein binding nucleus nucleus nucleoplasm nucleolus cytoplasm mitotic chromosome condensation mitotic chromosome condensation zinc ion binding protein transport nuclear matrix nuclear matrix nuclear matrix negative regulation of tumor necrosis factor production protein kinase A regulatory subunit binding protein kinase A regulatory subunit binding histone deacetylase binding cell cycle G2/M phase transition innate immune response metal ion binding NF-kappaB binding cellular response to lipopolysaccharide cellular response to prostaglandin E stimulus |
|
| 1417124_at |
Dstn |
destrin |
2 |
143915330 |
NM_019771 |
56431 |
76 |
cytokinesis actin binding cytoplasm cytoplasm actin cytoskeleton actin cytoskeleton actin filament depolymerization actin filament depolymerization actin filament fragmentation actin filament fragmentation positive regulation of actin filament depolymerization cortical actin cytoskeleton cell motility actin filament severing actin filament binding actin filament binding actin filament binding |
|
| 1454811_a_at |
Serinc1 |
serine incorporator 1 |
10 |
-57515774 |
AV026664 |
56442 |
26 |
endoplasmic reticulum endoplasmic reticulum membrane plasma membrane plasma membrane lipid metabolic process phosphatidylserine metabolic process sphingolipid metabolic process phospholipid biosynthetic process membrane membrane enzyme binding protein-macromolecule adaptor activity membrane biogenesis |
|
| 1416983_s_at |
Foxo1 |
forkhead box O1 |
3 |
52268336 |
AI462296 |
56458 |
820 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific transcription coactivator binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development nucleic acid binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm regulation of gluconeogenesis regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II autophagy apoptotic process DNA damage response beta-catenin binding transcription factor binding insulin receptor signaling pathway insulin receptor signaling pathway insulin receptor signaling pathway cellular response to starvation gene expression positive regulation of autophagy cell differentiation chromatin DNA binding ubiquitin protein ligase binding response to insulin cellular response to insulin stimulus negative regulation of stress-activated MAPK cascade cellular response to oxidative stress regulation of cell population proliferation glucose homeostasis positive regulation of apoptotic process negative regulation of apoptotic process sequence-specific DNA binding sequence-specific DNA binding negative regulation of fat cell differentiation positive regulation of gluconeogenesis positive regulation of gluconeogenesis positive regulation of protein catabolic process positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of insulin secretion protein phosphatase 2A binding canonical Wnt signaling pathway response to fatty acid cellular response to hyperoxia cellular response to nitric oxide negative regulation of canonical Wnt signaling pathway neuronal stem cell population maintenance negative regulation of cardiac muscle hypertrophy in response to stress promoter-specific chromatin binding regulation of neural precursor cell proliferation regulation of reactive oxygen species metabolic process |
04910 05200 05215 |
| 1423350_at |
Socs5 |
suppressor of cytokine signaling 5 |
17 |
87107678 |
AA510713 |
56468 |
35 |
epidermal growth factor receptor binding protein binding cytoplasm phosphatidylinositol 3-kinase complex epidermal growth factor receptor signaling pathway negative regulation of epidermal growth factor-activated receptor activity receptor signaling pathway via JAK-STAT negative regulation of signal transduction kinase inhibitor activity cytokine-mediated signaling pathway receptor tyrosine kinase binding positive regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of interleukin-6 production intracellular signal transduction positive regulation of T-helper 1 cell differentiation negative regulation of T-helper 2 cell differentiation phosphatidylinositol phosphate biosynthetic process 1-phosphatidylinositol-3-kinase regulator activity negative regulation of inflammatory response cellular response to low-density lipoprotein particle stimulus negative regulation of monocyte chemotactic protein-1 production vascular endothelial cell response to fluid shear stress negative regulation of endothelial cell activation |
04630 |
| 1422064_a_at |
Zbtb20 |
zinc finger and BTB domain containing 20 |
16 |
43247283, 42907644 |
AY028963 |
56490 |
339 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific regulation of cytokine production regulation of immune system process DNA binding nucleus nucleoplasm nucleoplasm cytoplasm negative regulation of gene expression nuclear body positive regulation of interferon-beta production positive regulation of interferon-beta production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of glycolytic process negative regulation of DNA-templated transcription metal ion binding positive regulation of lipid biosynthetic process lipid homeostasis cellular response to glucose stimulus sequence-specific double-stranded DNA binding |
|
| 1447806_s_at |
Srpk3 |
serine/arginine-rich protein specific kinase 3 |
X |
73774404 |
BB036235 |
56504 |
18 |
nucleotide binding spliceosomal complex assembly protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein phosphorylation multicellular organism development muscle organ development skeletal muscle tissue development kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation cell differentiation intracellular signal transduction regulation of mRNA processing muscle tissue development |
|
| 1422852_at |
Cib2 |
calcium and integrin binding family member 2 |
9 |
-54544793 |
NM_019686 |
56506 |
32 |
magnesium ion binding magnesium ion binding photoreceptor outer segment photoreceptor inner segment integrin binding calcium ion binding calcium ion binding calcium ion binding cytoplasm cytoplasm cytosol plasma membrane muscle tendon junction positive regulation of cytosolic calcium ion concentration membrane neuromuscular junction stereocilium stereocilium stereocilium cuticular plate sarcolemma protein homodimerization activity cell projection protein-containing complex binding photoreceptor cell maintenance metal ion binding calcium ion homeostasis calcium ion homeostasis cellular response to ATP cell periphery |
|
| 1425518_at |
Rapgef4 |
Rap guanine nucleotide exchange factor (GEF) 4 |
2 |
71981214, 72054616, 71981214 |
AK004874 |
56508 |
94 |
nucleotide binding photoreceptor outer segment photoreceptor inner segment guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm cytosol plasma membrane brush border exocytosis adenylate cyclase-modulating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway small GTPase-mediated signal transduction Ras protein signal transduction postsynaptic density positive regulation of smooth muscle cell migration membrane basolateral plasma membrane apical plasma membrane calcium-ion regulated exocytosis regulation of exocytosis insulin secretion axon dendrite growth cone cAMP binding cAMP binding protein-macromolecule adaptor activity small GTPase binding positive regulation of insulin secretion protein-containing complex intracellular signal transduction neuronal cell body dendritic spine positive regulation of GTPase activity cone cell pedicle protein-containing complex binding hormone secretion positive regulation of protein secretion regulation of dendrite development negative regulation of synaptic transmission excitatory synapse hippocampal mossy fiber to CA3 synapse hippocampal mossy fiber to CA3 synapse regulation of synaptic vesicle cycle regulation of synaptic vesicle cycle regulation of neurotransmitter receptor localization to postsynaptic specialization membrane glutamatergic synapse regulation of postsynapse organization positive regulation of neuronal action potential |
04670 |
| 1436819_at |
Septin6 |
septin 6 |
X |
-36911271, -36913443 |
BG920446 |
56526 |
63 |
nucleotide binding chromosome, centromeric region kinetochore GTPase activity protein binding GTP binding chromosome cytoplasm cytoskeleton cilium septin ring septin ring cell cycle spermatogenesis synaptic vesicle microtubule cytoskeleton cell differentiation septin complex septin complex septin complex motile cilium cell division site cleavage furrow septin collar cell projection axon terminus cell division molecular adaptor activity cilium assembly cytoskeleton-dependent cytokinesis sperm annulus presynapse |
|
| 1415897_a_at |
Mgst1 |
microsomal glutathione S-transferase 1 |
6 |
138141586, 138140526 |
BI150149 |
56615 |
32 |
glutathione transferase activity glutathione transferase activity glutathione transferase activity glutathione peroxidase activity mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial inner membrane peroxisomal membrane endoplasmic reticulum glutathione metabolic process response to xenobiotic stimulus response to organonitrogen compound membrane transferase activity response to lipopolysaccharide glutathione transport identical protein binding glutathione binding apical part of cell cellular response to lipid hydroperoxide |
00480 00980 00982 |
| 1420330_at |
Clec4e |
C-type lectin domain family 4, member e |
6 |
-123281788 |
NM_019948 |
56619 |
103 |
positive regulation of cytokine production pattern recognition receptor signaling pathway T cell differentiation involved in immune response immune system process calcium ion binding protein binding plasma membrane immune response external side of plasma membrane membrane carbohydrate binding carbohydrate binding phagocytic vesicle membrane signaling receptor activity Fc-gamma receptor signaling pathway pattern recognition receptor activity pattern recognition receptor activity pattern recognition receptor activity defense response to bacterium cell projection innate immune response innate immune response metal ion binding glycolipid binding antifungal innate immune response antifungal innate immune response |
|
| 1425951_a_at |
Clec4n |
C-type lectin domain family 4, member n |
6 |
123229842 |
AF240358 |
56620 |
96 |
positive regulation of cytokine production response to yeast detection of yeast stimulatory C-type lectin receptor signaling pathway adaptive immune response immune system process calcium ion binding protein binding mannose binding plasma membrane plasma membrane external side of plasma membrane membrane carbohydrate binding carbohydrate binding carbohydrate binding pattern recognition receptor activity pattern recognition receptor activity positive regulation of canonical NF-kappaB signal transduction innate immune response metal ion binding positive regulation of peptidyl-tyrosine phosphorylation defense response to fungus antifungal innate immune response antifungal innate immune response positive regulation of intracellular signal transduction positive regulation of T-helper 17 type immune response |
|
| 1420699_at |
Clec7a |
C-type lectin domain family 7, member a |
6 |
-129461590, -129461590 |
NM_020008 |
56644 |
251 |
cell activation opsonin binding (1->3)-beta-D-glucan binding (1->3)-beta-D-glucan binding (1->3)-beta-D-glucan binding (1->3)-beta-D-glucan immune receptor activity response to yeast detection of yeast stimulatory C-type lectin receptor signaling pathway response to molecule of fungal origin leukocyte activation involved in immune response immune system process positive regulation of cytokine production involved in immune response positive regulation of dendritic cell cytokine production positive regulation of dendritic cell cytokine production cell surface pattern recognition receptor signaling pathway protein binding cytoplasm plasma membrane plasma membrane phagocytosis, recognition phagocytosis, recognition phagocytosis, recognition phagocytosis, engulfment inflammatory response cell recognition positive regulation of cell population proliferation positive regulation of cell population proliferation external side of plasma membrane cell surface cell surface positive regulation of gene expression membrane detection of fungus detection of fungus carbohydrate binding polysaccharide binding positive regulation of cell migration positive regulation of cell migration positive regulation of protein-containing complex assembly detection of molecule of fungal origin detection of molecule of fungal origin detection of molecule of fungal origin positive regulation of type II interferon production positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-2 production positive regulation of interleukin-2 production positive regulation of interleukin-23 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade positive regulation of superoxide anion generation pattern recognition receptor activity pattern recognition receptor activity pattern recognition receptor activity pattern recognition receptor activity identical protein binding regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of cysteine-type endopeptidase activity involved in apoptotic process innate immune response positive regulation of nitric oxide biosynthetic process metal ion binding positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phagocytosis positive regulation of phagocytosis positive regulation of phagocytosis positive regulation of calcium-mediated signaling positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of lymphocyte activation positive regulation of lymphocyte activation positive regulation of killing of cells of another organism positive regulation of killing of cells of another organism positive regulation of respiratory burst antifungal innate immune response antifungal innate immune response regulation of calcineurin-NFAT signaling cascade cellular response to molecule of fungal origin cellular response to molecule of fungal origin cellular response to molecule of fungal origin positive regulation of monocyte chemotactic protein-1 production positive regulation of wound healing positive regulation of wound healing cell-cell adhesion positive regulation of cytokine production involved in inflammatory response positive regulation of cytokine production involved in inflammatory response positive regulation of cell maturation positive regulation of T-helper 17 type immune response |
04145 |
| 1437270_a_at |
Clcf1 |
cardiotrophin-like cytokine factor 1 |
19 |
4214388, 4214237 |
BB825816 |
56708 |
35 |
positive regulation of immunoglobulin production positive regulation of type 2 immune response signaling receptor binding cytokine activity cytokine activity cytokine activity ciliary neurotrophic factor receptor binding ciliary neurotrophic factor receptor binding protein binding extracellular region extracellular region extracellular space cell surface receptor signaling pathway receptor signaling pathway via JAK-STAT receptor signaling pathway via JAK-STAT positive regulation of cell population proliferation B cell differentiation positive regulation of B cell proliferation positive regulation of B cell proliferation positive regulation of tyrosine phosphorylation of STAT protein positive regulation of tyrosine phosphorylation of STAT protein positive regulation of tyrosine phosphorylation of STAT protein negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process positive regulation of isotype switching to IgE isotypes positive regulation of astrocyte differentiation regulation of inflammatory response positive regulation of corticotropin-releasing hormone secretion regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of ERK1 and ERK2 cascade CRLF-CLCF1 complex CRLF-CLCF1 complex CRLF-CLCF1 complex CNTFR-CLCF1 complex CNTFR-CLCF1 complex negative regulation of motor neuron apoptotic process |
04060 04630 |
| 1423323_at |
Tacstd2 |
tumor-associated calcium signal transducer 2 |
6 |
-67534058 |
AV241768 |
56753 |
35 |
extracellular space extracellular space nucleus nucleus plasma membrane basal plasma membrane negative regulation of epithelial cell migration membrane lateral plasma membrane regulation of epithelial cell proliferation negative regulation of stress fiber assembly ureteric bud morphogenesis negative regulation of branching involved in ureteric bud morphogenesis negative regulation of substrate adhesion-dependent cell spreading negative regulation of ruffle assembly negative regulation of cell motility positive regulation of stem cell differentiation positive regulation of stem cell differentiation |
|
| 1440315_at |
Mbnl1 |
muscleblind like splicing regulator 1 |
3 |
60501178, 60472829 |
BB202204 |
56758 |
102 |
alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome regulatory region RNA binding in utero embryonic development RNA binding RNA binding double-stranded RNA binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytoplasm cytosol mRNA splice site recognition mRNA processing nervous system development skeletal muscle tissue development RNA splicing cytoplasmic stress granule embryonic limb morphogenesis regulation of RNA splicing regulation of RNA splicing myoblast differentiation metal ion binding |
|
| 1449738_s_at |
Supt20 |
SPT20 SAGA complex component |
3 |
54692814, 54695122, 54693104 |
C80158 |
56790 |
29 |
SAGA complex SAGA complex transcription coregulator activity transcription coregulator activity regulation of DNA repair regulation of transcription by RNA polymerase II multicellular organism development gastrulation regulation of RNA splicing positive regulation of gluconeogenesis positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II SAGA-type complex |
|
| 1440284_at |
Stap1 |
signal transducing adaptor family member 1 |
5 |
86071745 |
AI506066 |
56792 |
27 |
phosphotyrosine residue binding transmembrane receptor protein tyrosine kinase adaptor activity macrophage colony-stimulating factor receptor binding protein binding nucleus nucleoplasm cytoplasm mitochondrion cytosol transmembrane receptor protein tyrosine kinase signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway response to bacterium positive regulation of gene expression negative regulation of macrophage chemotaxis protein kinase binding protein kinase binding myeloid cell differentiation protein tyrosine kinase activator activity protein-macromolecule adaptor activity receptor tyrosine kinase binding protein-containing complex centriolar satellite signaling adaptor activity signaling adaptor activity negative regulation of phosphorylation positive regulation of B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway positive regulation of phagocytosis, engulfment cellular response to lipopolysaccharide negative regulation of ruffle assembly negative regulation of macrophage colony-stimulating factor signaling pathway positive regulation of microglial cell activation negative regulation of microglial cell migration positive regulation of microglial cell mediated cytotoxicity |
|
| 1436959_x_at |
Nsmf |
NMDA receptor synaptonuclear signaling and neuronal migration factor |
2 |
25054378 |
BB311061 |
56876 |
39 |
euchromatin protein binding nucleus nucleus nucleus nuclear envelope nucleoplasm cytoplasm cytoplasm cytoplasm cytoskeleton plasma membrane postsynaptic density membrane nuclear matrix dendrite cortical cytoskeleton nuclear membrane positive regulation of protein dephosphorylation cell projection neuron projection dendritic spine perikaryon regulation of neuron apoptotic process synapse regulation of neuronal synaptic plasticity calcium-dependent protein binding regulation of dendrite morphogenesis cellular response to amino acid stimulus cellular response to electrical stimulus cellular response to gonadotropin stimulus apical dendrite postsynapse glutamatergic synapse postsynapse to nucleus signaling pathway regulation of neuron migration positive regulation of neuron migration positive regulation of neuron migration |
|
| 1425890_at |
Ly6i |
lymphocyte antigen 6 family member I |
15 |
-74979533 |
AF232024 |
57248 |
13 |
plasma membrane plasma membrane membrane acetylcholine receptor inhibitor activity acetylcholine receptor binding acetylcholine receptor signaling pathway side of membrane |
|
| 1449015_at |
Retnla |
resistin like alpha |
16 |
48842608 |
NM_020509 |
57262 |
89 |
hormone activity extracellular region extracellular space |
|
| 1423108_at |
Slc25a20 |
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 |
9 |
108662135 |
AV008091 |
57279 |
36 |
in utero embryonic development mitochondrion mitochondrion mitochondrial envelope mitochondrial inner membrane cytosol mitochondrial transport lipid transport acyl carnitine transmembrane transporter activity acyl carnitine transmembrane transporter activity membrane carnitine transmembrane transport carnitine transmembrane transport |
|
| 1426100_a_at |
Tk2 |
thymidine kinase 2, mitochondrial |
8 |
-104226690 |
AF105217 |
57813 |
37 |
nucleotide binding deoxycytidine kinase activity deoxycytidine kinase activity thymidine kinase activity thymidine kinase activity thymidine kinase activity ATP binding cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane nucleobase-containing compound metabolic process mitochondrial DNA replication deoxyribonucleotide metabolic process kinase activity phosphorylation transferase activity deoxynucleoside kinase activity deoxynucleoside kinase activity mitochondrial DNA metabolic process deoxycytidine metabolic process thymidine metabolic process DNA biosynthetic process |
00240 00983 01100 |
| 1421479_at |
Zfp318 |
zinc finger protein 318 |
17 |
46383765 |
NM_021346 |
57908 |
28 |
nucleic acid binding protein binding nucleus nucleoplasm nucleoplasm cytosol zinc ion binding protein homodimerization activity negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription metal ion binding protein heterodimerization activity meiotic cell cycle |
|
| 1423182_at |
Tnfrsf13b |
tumor necrosis factor receptor superfamily, member 13b |
11 |
61142483, 61126754 |
AK004668 |
57916 |
86 |
B cell homeostasis B cell homeostasis B cell homeostasis hematopoietic progenitor cell differentiation hematopoietic progenitor cell differentiation adaptive immune response immune system process plasma membrane external side of plasma membrane membrane negative regulation of B cell proliferation negative regulation of B cell proliferation |
04060 04672 05340 |
| 1456261_at |
Sh3kbp1 |
SH3-domain kinase binding protein 1 |
X |
159942692, 159627271, 159840467, 159708600, 159627283 |
BB766215 |
58194 |
54 |
protein binding cytoplasm cytoskeleton cell-cell junction endocytosis apoptotic process cytoskeleton organization actin filament organization regulation of cell shape membrane cell migration cell migration SH3 domain binding endocytic vesicle cytoplasmic vesicle ubiquitin protein ligase binding neuron projection synapse positive regulation of B cell activation molecular adaptor activity ubiquitin-dependent endocytosis anchoring junction |
04144 |
| 1429947_a_at |
Zbp1 |
Z-DNA binding protein 1 |
2 |
-173206611, -173213735 |
AK008179 |
58203 |
85 |
activation of innate immune response activation of innate immune response immune system process DNA binding DNA binding DNA binding left-handed Z-DNA binding RNA binding double-stranded RNA binding double-stranded RNA adenosine deaminase activity protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytosol cytosol apoptotic process programmed cell death identical protein binding positive regulation of apoptotic process positive regulation of apoptotic process innate immune response regulation of inflammatory response positive regulation of inflammatory response defense response to fungus defense response to virus defense response to virus defense response to virus positive regulation of type I interferon-mediated signaling pathway positive regulation of type I interferon-mediated signaling pathway positive regulation of necroptotic process positive regulation of necroptotic process positive regulation of necroptotic process pyroptosis antiviral innate immune response regulation of interleukin-1-mediated signaling pathway |
04623 |
| 1452966_at |
Bcl11b |
B cell leukemia/lymphoma 11B |
12 |
-107910402 |
AK020296 |
58208 |
764 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific keratinocyte development epithelial cell morphogenesis DNA-binding transcription factor activity protein binding intracellular anatomical structure nucleus nucleus transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II apoptotic process axonogenesis negative regulation of cell population proliferation post-embryonic development regulation of gene expression regulation of keratinocyte proliferation SWI/SNF complex SWI/SNF complex regulation of lipid metabolic process striatal medium spiny neuron differentiation commitment of neuronal cell to specific neuron type in forebrain central nervous system neuron differentiation post-embryonic camera-type eye development T cell differentiation in thymus T cell receptor V(D)J recombination hematopoietic stem cell migration odontogenesis of dentin-containing tooth neuron projection positive T cell selection sequence-specific DNA binding skin development regulation of neuron differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II alpha-beta T cell differentiation metal ion binding thymus development T cell apoptotic process negative regulation of T cell apoptotic process thymocyte apoptotic process negative regulation of thymocyte apoptotic process olfactory bulb axon guidance lymphoid lineage cell migration into thymus sequence-specific double-stranded DNA binding |
|
| 1447284_at |
Trem1 |
triggering receptor expressed on myeloid cells 1 |
17 |
48232738 |
BB784999 |
58217 |
126 |
cytokine production positive regulation of cell-matrix adhesion adaptive immune response cytokine production involved in immune response cytokine production involved in immune response immune system process transmembrane signaling receptor activity extracellular space plasma membrane cell surface positive regulation of cardiac muscle cell apoptotic process positive regulation of macrophage chemotaxis membrane neutrophil chemotaxis neutrophil chemotaxis chemokine production chemokine production innate immune response neutrophil-mediated killing of gram-negative bacterium neutrophil-mediated killing of gram-negative bacterium neutrophil extravasation scaffold protein binding receptor decoy activity neutrophil migration |
|
| 1460271_at |
Trem3 |
triggering receptor expressed on myeloid cells 3 |
17 |
48247728 |
NM_021407 |
58218 |
23 |
cytokine production cytokine production involved in immune response cytokine production involved in immune response protein binding plasma membrane membrane cell migration neutrophil chemotaxis neutrophil chemotaxis chemokine production chemokine production positive regulation of innate immune response neutrophil-mediated killing of gram-negative bacterium neutrophil-mediated killing of gram-negative bacterium neutrophil extravasation |
|
| 1421977_at |
Mmp19 |
matrix metallopeptidase 19 |
10 |
128790909, 128790954 |
AF153199 |
58223 |
33 |
angiogenesis metalloendopeptidase activity metalloendopeptidase activity metalloendopeptidase activity extracellular region extracellular region extracellular space extracellular space plasma membrane proteolysis multicellular organism development peptidase activity metallopeptidase activity zinc ion binding membrane hydrolase activity cell differentiation extracellular matrix organization collagen catabolic process collagen catabolic process extracellular matrix metal ion binding side of membrane |
|
| 1460174_at |
Dexi |
dexamethasone-induced transcript |
16 |
-10530206 |
NM_021428 |
58239 |
17 |
molecular_function cellular_component biological_process |
|
| 1416799_at |
Trpm7 |
transient receptor potential cation channel, subfamily M, member 7 |
2 |
-126791557 |
AV320241 |
58800 |
146 |
nucleotide binding ruffle actin binding protein kinase activity protein serine/threonine kinase activity monoatomic ion channel activity monoatomic cation channel activity calcium channel activity calcium channel activity calcium channel activity protein binding ATP binding plasma membrane protein phosphorylation monoatomic ion transport calcium ion transport calcium ion transport calcium ion transport memory intracellular magnesium ion homeostasis programmed cell death membrane kinase activity phosphorylation calcium-dependent cell-matrix adhesion transferase activity myosin binding synaptic vesicle membrane actomyosin structure organization monoatomic ion transmembrane transport neuronal cell body positive regulation of apoptotic process varicosity protein autophosphorylation metal ion binding protein tetramerization transmembrane transport necroptotic process calcium ion transmembrane transport monoatomic cation transmembrane transport |
|
| 1420641_a_at |
Sqor |
sulfide quinone oxidoreductase |
2 |
122771712, 122781998, 122765358 |
AF174535 |
59010 |
26 |
mitochondrion mitochondrion mitochondrial inner membrane oxidoreductase activity quinone binding sulfide oxidation, using sulfide:quinone oxidoreductase sulfide oxidation, using sulfide:quinone oxidoreductase sulfide:quinone oxidoreductase activity sulfide:quinone oxidoreductase activity FAD binding glutathione-dependent sulfide quinone oxidoreductase activity |
|
| 1418530_at |
Nup160 |
nucleoporin 160 |
2 |
90677214 |
NM_021512 |
59015 |
31 |
kinetochore nucleus nuclear envelope nuclear pore nuclear pore nuclear pore nuclear pore mRNA export from nucleus mRNA export from nucleus nucleocytoplasmic transport protein transport structural constituent of nuclear pore structural constituent of nuclear pore structural constituent of nuclear pore nuclear pore outer ring mRNA transport nephron development |
03013 |
| 1417190_at |
Nampt |
nicotinamide phosphoribosyltransferase |
12 |
32820334 |
AW989410 |
59027 |
189 |
nucleotide binding microglial cell activation cytokine activity extracellular region extracellular space nucleus cytoplasm cytosol circadian rhythm NAD biosynthetic process NAD biosynthetic process negative regulation of autophagy regulation of lung blood pressure nuclear speck transferase activity glycosyltransferase activity pyridine nucleotide biosynthetic process cell junction circadian regulation of gene expression identical protein binding identical protein binding positive regulation of transcription by RNA polymerase II nicotinamide phosphoribosyltransferase activity nicotinamide phosphoribosyltransferase activity nicotinamide phosphoribosyltransferase activity rhythmic process positive regulation of smooth muscle cell proliferation positive regulation of nitric-oxide synthase biosynthetic process heterocyclic compound binding negative regulation of cellular senescence |
00760 |
| 1417710_at |
Mettl9 |
methyltransferase like 9 |
7 |
121034444 |
NM_021554 |
59052 |
19 |
mitochondrion endoplasmic reticulum methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity transferase activity methylation protein-L-histidine N-pros-methyltransferase activity protein-L-histidine N-pros-methyltransferase activity |
|
| 1423467_at |
Ms4a4b |
membrane-spanning 4-domains, subfamily A, member 4B |
19 |
11443557 |
BB199001 |
60361 |
20 |
Golgi apparatus plasma membrane plasma membrane |
|
| 1417719_at |
Sap30 |
sin3 associated polypeptide |
8 |
-57482701 |
NM_021788 |
60406 |
31 |
histone deacetylase complex histone deacetylase complex negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II DNA binding transcription coregulator activity transcription corepressor activity protein binding nucleus nucleus nucleoplasm nucleoplasm regulation of DNA-templated transcription negative regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway skeletal muscle cell differentiation metal ion binding modulation by host of symbiont transcription Sin3-type complex negative regulation of stem cell population maintenance positive regulation of stem cell population maintenance |
|
| 1419043_a_at |
Iigp1 |
interferon inducible GTPase 1 |
18 |
60376028, 60373615 |
BM239828 |
60440 |
45 |
nucleotide binding immune system process GTPase activity GTPase activity GTPase activity protein binding GTP binding nucleus cytoplasm endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane Golgi apparatus defense response response to bacterium regulation of autophagy membrane hydrolase activity GDP binding cytokine-mediated signaling pathway symbiont-containing vacuole membrane cellular response to interferon-beta cellular response to interferon-beta identical protein binding identical protein binding defense response to protozoan innate immune response defense response to Gram-negative bacterium |
|
| 1422478_a_at |
Acss2 |
acyl-CoA synthetase short-chain family member 2 |
2 |
155518042 |
NM_019811 |
60525 |
51 |
nucleotide binding chromatin binding transcription coactivator activity acetate-CoA ligase activity acetate-CoA ligase activity acetate-CoA ligase activity acetate-CoA ligase activity protein binding ATP binding nucleus nucleus cytoplasm cytoplasm cytosol cytosol acetyl-CoA biosynthetic process acetyl-CoA biosynthetic process lipid metabolic process long-term memory lipid biosynthetic process ligase activity acetate biosynthetic process propionate biosynthetic process propionate-CoA ligase activity |
00010 00620 00640 01100 |
| 1419714_at |
Cd274 |
CD274 antigen |
19 |
29367437 |
NM_021893 |
60533 |
509 |
adaptive immune response immune system process positive regulation of tolerance induction to tumor cell transcription coactivator activity protein binding nucleoplasm endosome plasma membrane immune response immune response signal transduction cell surface receptor signaling pathway cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane cell surface actin cytoskeleton membrane positive regulation of cell migration T cell costimulation T cell costimulation early endosome membrane negative regulation of type II interferon production negative regulation of interleukin-10 production positive regulation of interleukin-10 production response to cytokine TRIF-dependent toll-like receptor signaling pathway positive regulation of T cell proliferation positive regulation of T cell proliferation negative regulation of T cell proliferation negative regulation of T cell proliferation negative regulation of activated T cell proliferation recycling endosome membrane extracellular exosome cellular response to lipopolysaccharide negative regulation of tumor necrosis factor superfamily cytokine production positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of CD8-positive, alpha-beta T cell activation |
04514 |
| 1451370_at |
Ccdc107 |
coiled-coil domain containing 107 |
4 |
43493364 |
BC027414 |
622404 |
12 |
molecular_function cellular_component biological_process membrane |
|
| 1441887_x_at |
Gm6377 |
predicted gene 6377 |
X |
109196755 |
BB548587 |
622976 |
11 |
molecular_function cellular_component regulation of lysosomal lumen pH |
|
| 1438238_at |
2010315B03Rik |
RIKEN cDNA 2010315B03 gene |
9 |
-124291803 |
BB744779 |
630836 |
10 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity regulation of transcription by RNA polymerase II |
|
| 1426607_at |
Tmem267 |
transmembrane protein 267 |
13 |
119488472, 119488085 |
BG068672 |
633640 |
13 |
molecular_function cellular_component biological_process membrane |
|
| 1449976_a_at |
Gpr35 |
G protein-coupled receptor 35 |
1 |
92978902, 92973118, 92975346 |
NM_022320 |
64095 |
42 |
G protein-coupled receptor activity G protein-coupled receptor activity chemokine receptor activity plasma membrane plasma membrane cytoskeleton organization signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration membrane positive regulation of Rho protein signal transduction macrophage chemotaxis chemokine-mediated signaling pathway negative regulation of voltage-gated calcium channel activity negative regulation of neuronal action potential |
04080 |
| 1418206_at |
Sdf2l1 |
stromal cell-derived factor 2-like 1 |
16 |
-17130137 |
NM_022324 |
64136 |
21 |
endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum chaperone complex response to endoplasmic reticulum stress ERAD pathway regulation of apoptotic process chaperone cofactor-dependent protein refolding protein-folding chaperone binding ATPase binding misfolded protein binding cellular response to misfolded protein protein folding chaperone complex |
|
| 1435517_x_at |
Ralb |
v-ral simian leukemia viral oncogene B |
1 |
-119470304 |
BB465250 |
64143 |
33 |
nucleotide binding regulation of exocyst assembly positive regulation of protein phosphorylation GTPase activity GTPase activity G protein activity GTP binding GTP binding plasma membrane plasma membrane apoptotic process cell cycle signal transduction Ras protein signal transduction cellular response to starvation membrane hydrolase activity GDP binding GDP binding midbody receptor internalization ubiquitin protein ligase binding negative regulation of protein binding positive regulation of protein binding positive regulation of epidermal growth factor receptor signaling pathway ATPase binding cell division regulation of exocyst localization cellular response to exogenous dsRNA positive regulation of protein serine/threonine kinase activity positive regulation of autophagosome assembly |
05200 05212 |
| 1416863_at |
Abhd8 |
abhydrolase domain containing 8 |
8 |
-71456699 |
NM_022419 |
64296 |
18 |
catalytic activity hydrolase activity |
|
| 1418797_at |
Ms4a8a |
membrane-spanning 4-domains, subfamily A, member 8A |
19 |
-11067470 |
NM_022430 |
64381 |
14 |
plasma membrane plasma membrane cell surface receptor signaling pathway membrane |
|
| 1417527_at |
Ap3m2 |
adaptor-related protein complex 3, mu 2 subunit |
8 |
-22787353 |
BC027301 |
64933 |
26 |
early endosome Golgi apparatus intracellular protein transport endocytosis anterograde axonal transport protein transport membrane synaptic vesicle coating vesicle-mediated transport AP-3 adaptor complex clathrin adaptor complex cytoplasmic vesicle cytoplasmic vesicle clathrin-coated vesicle cargo loading, AP-3-mediated synaptic vesicle recycling intracellular transport anterograde synaptic vesicle transport |
04142 |
| 1437236_a_at |
Zfp110 |
zinc finger protein 110 |
7 |
12834760 |
AV263718 |
65020 |
33 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding chromatin binding neurotrophin p75 receptor binding protein binding nucleus cytoplasm cytosol chromatin remodeling regulation of DNA-templated transcription regulation of transcription by RNA polymerase II apoptotic process sequence-specific DNA binding regulation of JNK cascade metal ion binding neuron apoptotic process extrinsic apoptotic signaling pathway retinal cell apoptotic process sequence-specific double-stranded DNA binding |
04722 |
| 1420697_at |
Slc15a3 |
solute carrier family 15, member 3 |
19 |
10842543 |
NM_023044 |
65221 |
18 |
immune system process lysosome lysosomal membrane lysosomal membrane lysosomal membrane endosome oligopeptide transport endosome membrane protein transport symporter activity peptidoglycan transmembrane transporter activity peptide transport peptidoglycan transport membrane transmembrane transporter activity intracellular membrane-bounded organelle innate immune response transmembrane transport positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway dipeptide transmembrane transporter activity dipeptide transmembrane transporter activity dipeptide import across plasma membrane dipeptide import across plasma membrane |
|
| 1415682_at |
Xpo7 |
exportin 7 |
14 |
-70662125, -70662125 |
NM_023045 |
65246 |
34 |
nuclear export signal receptor activity nuclear export signal receptor activity protein binding nucleus nuclear pore nuclear pore cytoplasm cytoplasm protein export from nucleus protein export from nucleus intracellular protein transport nucleocytoplasmic transport protein transport small GTPase binding nuclear transport |
|
| 1440845_at |
Tmem243 |
transmembrane protein 243, mitochondrial |
5 |
9100736 |
BB323696 |
652925 |
11 |
molecular_function cellular_component biological_process |
|
| 1448263_a_at |
Cndp2 |
CNDP dipeptidase 2 |
18 |
-84667464, -84667464 |
NM_023149 |
66054 |
41 |
carboxypeptidase activity nucleoplasm cytoplasm cytosol cytosol proteolysis proteolysis proteolysis peptidase activity metallopeptidase activity hydrolase activity dipeptidase activity dipeptidase activity dipeptidase activity metal ion binding metallodipeptidase activity alanylglutamate dipeptidase activity |
|
| 1447678_at |
Hsd17b14 |
hydroxysteroid (17-beta) dehydrogenase 14 |
7 |
45554927 |
BB399925 |
66065 |
14 |
estradiol 17-beta-dehydrogenase [NAD(P)] activity estradiol 17-beta-dehydrogenase [NAD(P)] activity cytosol cytosol steroid catabolic process steroid catabolic process identical protein binding testosterone 17-beta-dehydrogenase (NADP+) activity |
|
| 1419103_a_at |
Abhd6 |
abhydrolase domain containing 6 |
14 |
8002887, 8002965 |
NM_025341 |
66082 |
41 |
catalytic activity phospholipase activity mitochondrion mitochondrion lysosome lysosomal membrane endosome lipid metabolic process phospholipid catabolic process membrane hydrolase activity negative regulation of cell migration late endosome membrane AMPA glutamate receptor complex postsynaptic membrane acylglycerol catabolic process acylglycerol catabolic process acylglycerol catabolic process positive regulation of lipid biosynthetic process acylglycerol lipase activity acylglycerol lipase activity acylglycerol lipase activity acylglycerol lipase activity monoacylglycerol catabolic process long-term synaptic depression glutamatergic synapse glutamatergic synapse GABA-ergic synapse regulation of retrograde trans-synaptic signaling by endocanabinoid regulation of retrograde trans-synaptic signaling by endocanabinoid negative regulation of cold-induced thermogenesis regulation of endocannabinoid signaling pathway lysobisphosphatidic acid metabolic process |
|
| 1428797_at |
Setd6 |
SET domain containing 6 |
8 |
95715912 |
AK010304 |
66083 |
22 |
protein binding nucleus nucleus nucleoplasm cytosol methyltransferase activity protein-lysine N-methyltransferase activity protein-lysine N-methyltransferase activity transferase activity peptidyl-lysine methylation peptidyl-lysine monomethylation peptidyl-lysine monomethylation stem cell population maintenance negative regulation of NF-kappaB transcription factor activity methylation stem cell differentiation regulation of inflammatory response NF-kappaB binding S-adenosyl-L-methionine binding |
|
| 1434484_at |
Wfdc21 |
WAP four-disulfide core domain 21 |
11 |
83746939 |
AV006463 |
66107 |
13 |
serine-type endopeptidase inhibitor activity extracellular region extracellular space extracellular space enzyme activator activity antibacterial humoral response peptidase inhibitor activity response to lipopolysaccharide response to tumor necrosis factor innate immune response white fat cell differentiation |
|
| 1423754_at |
Ifitm3 |
interferon induced transmembrane protein 3 |
7 |
-141009589 |
BC010291 |
66141 |
97 |
immune system process nucleus cytoplasm lysosome lysosomal membrane endosome endoplasmic reticulum plasma membrane plasma membrane plasma membrane receptor-mediated endocytosis negative regulation of cell population proliferation response to virus cell surface membrane cytoplasmic vesicle early endosome membrane protein-containing complex response to type II interferon response to interferon-alpha response to interferon-beta negative regulation of viral genome replication innate immune response apical part of cell negative regulation of viral entry into host cell negative regulation of viral entry into host cell defense response to virus defense response to virus defense response to virus defense response to virus type I interferon-mediated signaling pathway type I interferon-mediated signaling pathway |
|
| 1428883_at |
Maco1 |
macoilin 1 |
4 |
-134802760, -134802759 |
AK003528 |
66146 |
25 |
nucleus endoplasmic reticulum chemotaxis brain development microtubule binding membrane neuronal signal transduction neuronal signal transduction axon rough endoplasmic reticulum membrane rough endoplasmic reticulum membrane nuclear membrane nuclear membrane neuron projection neuron projection terminus synapse |
|
| 1429520_a_at |
Acer3 |
alkaline ceramidase 3 |
7 |
-98213809, -98213809 |
BE573407 |
66190 |
19 |
Golgi membrane calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus lipid metabolic process sphingolipid metabolic process ceramide metabolic process inflammatory response zinc ion binding positive regulation of cell population proliferation membrane hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides N-acylsphingosine amidohydrolase activity myelination regulation of programmed cell death sphingosine biosynthetic process sphingosine biosynthetic process ceramide catabolic process ceramide catabolic process metal ion binding phytoceramidase activity phytoceramidase activity phytoceramidase activity phytosphingosine biosynthetic process phytosphingosine biosynthetic process dihydroceramidase activity ceramidase activity |
00600 |
| 1448919_at |
Cd302 |
CD302 antigen |
2 |
-60251992 |
NM_025422 |
66205 |
16 |
cytoplasm cell cortex phagocytosis external side of plasma membrane membrane filopodium carbohydrate binding signaling receptor activity cell projection |
|
| 1424683_at |
Retreg1 |
reticulophagy regulator 1 |
15 |
25933551, 25940825, 25843297, 25940701, 25942678 |
BC019494 |
66270 |
34 |
mitophagy protein binding nucleolus endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus cis-Golgi network autophagy endoplasmic reticulum organization membrane nuclear body sensory perception of pain collagen catabolic process negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process protein self-association white fat cell differentiation reticulophagy reticulophagy reticulophagy reticulophagy endoplasmic reticulum-autophagosome adaptor activity |
|
| 1438413_at |
Senp7 |
SUMO1/sentrin specific peptidase 7 |
16 |
56075403, 56057529, 56075403, 56075479 |
AV231698 |
66315 |
28 |
immune system process protein binding nucleus nucleus cytoplasm cytoplasm proteolysis peptidase activity cysteine-type peptidase activity hydrolase activity protein desumoylation protein desumoylation innate immune response SUMO-specific endopeptidase activity SUMO-specific endopeptidase activity antiviral innate immune response |
|
| 1416775_at |
Dmac2 |
distal membrane arm assembly complex 2 |
7 |
25619492, 25619413 |
NM_025504 |
66349 |
13 |
mitochondrion mitochondrial respiratory chain complex I SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process mitochondrial respiratory chain complex I assembly mitochondrial respiratory chain complex I assembly |
|
| 1426440_at |
Dhrs7 |
dehydrogenase/reductase 7 |
12 |
-72650352 |
AK009385 |
66375 |
19 |
carbonyl reductase (NADPH) activity endoplasmic reticulum endoplasmic reticulum membrane membrane oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor retinol metabolic process NADP-retinol dehydrogenase activity |
|
| 1435346_at |
Ccdc82 |
coiled-coil domain containing 82 |
9 |
13246955 |
BE352816 |
66396 |
12 |
molecular_function nucleus biological_process |
|
| 1417138_s_at |
Polr2e |
polymerase (RNA) II (DNA directed) polypeptide E |
10 |
-80035952 |
NM_025554 |
66420 |
24 |
DNA-directed RNA polymerase complex RNA polymerase I activity RNA polymerase II activity RNA polymerase III activity DNA binding DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm nucleoplasm RNA polymerase II, core complex RNA polymerase II, core complex RNA polymerase III complex RNA polymerase III complex RNA polymerase I complex RNA polymerase I complex DNA-templated transcription transcription elongation by RNA polymerase I transcription by RNA polymerase II transcription by RNA polymerase II tRNA transcription by RNA polymerase III RPAP3/R2TP/prefoldin-like complex |
00230 00240 01100 03020 05016 |
| 1455170_at |
2810001G20Rik |
RIKEN cDNA 2810001G20 gene |
11 |
64079483 |
BB250227 |
66456 |
12 |
molecular_function cellular_component biological_process |
|
| 1417075_at |
Fam136a |
family with sequence similarity 136, member A |
6 |
86365645, 86365470 |
NM_025591 |
66488 |
18 |
molecular_function cytoplasm cytoplasm mitochondrion biological_process |
|
| 1436153_a_at |
Zmynd11 |
zinc finger, MYND domain containing 11 |
13 |
-9684835, -9684835, -9684835, -9684835 |
BB561053 |
66505 |
27 |
DNA binding double-stranded DNA binding transcription corepressor activity protein binding nucleus nucleus nucleoplasm chromosome chromatin organization zinc ion binding zinc ion binding regulation of signal transduction regulation of transcription elongation by RNA polymerase II regulation of transcription elongation by RNA polymerase II methylated histone binding methylated histone binding methylated histone binding histone binding negative regulation of canonical NF-kappaB signal transduction negative regulation of JNK cascade metal ion binding defense response to virus negative regulation of extrinsic apoptotic signaling pathway |
|
| 1425193_at |
Sppl2a |
signal peptide peptidase like 2A |
2 |
-126890394 |
BC026578 |
66552 |
34 |
lysosome lysosomal membrane lysosomal membrane endosome late endosome plasma membrane proteolysis membrane protein ectodomain proteolysis peptidase activity membrane hydrolase activity Golgi-associated vesicle membrane Golgi-associated vesicle membrane membrane protein intracellular domain proteolysis late endosome membrane membrane protein proteolysis membrane protein proteolysis membrane protein proteolysis aspartic endopeptidase activity, intramembrane cleaving aspartic endopeptidase activity, intramembrane cleaving protein homodimerization activity intracellular membrane-bounded organelle regulation of immune response regulation of immune response lumenal side of endoplasmic reticulum membrane cytoplasmic side of endoplasmic reticulum membrane |
|
| 1437041_at |
Pnisr |
PNN interacting serine/arginine-rich |
4 |
21848047 |
BB120903 |
66625 |
22 |
molecular_function nucleus nucleoplasm cytosol plasma membrane biological_process nuclear speck nuclear speck presynaptic active zone |
|
| 1438442_at |
Sike1 |
suppressor of IKBKE 1 |
3 |
102995739 |
AI450236 |
66641 |
14 |
molecular_function cytoplasm biological_process protein kinase binding small GTPase binding |
04622 |
| 1434662_at |
Atg4a |
autophagy related 4A, cysteine peptidase |
X |
140956906, 140953844 |
BM237732 |
666468 |
16 |
autophagosome assembly autophagosome assembly mitophagy cysteine-type endopeptidase activity cytoplasm C-terminal protein lipidation proteolysis autophagy cysteine-type peptidase activity protein processing protein-phosphatidylethanolamide deconjugating activity protein-phosphatidylethanolamide deconjugating activity piecemeal microautophagy of the nucleus aggrephagy protein delipidation protein delipidation |
04140 |
| 1442219_at |
Gm8369 |
predicted gene 8369 |
19 |
11492037 |
BB218965 |
666926 |
9 |
molecular_function Golgi apparatus plasma membrane biological_process |
|
| 1425738_at |
Igkv3-12 |
immunoglobulin kappa variable 3-12 |
6 |
|
M35669 |
667914 |
3 |
immunoglobulin production extracellular space extracellular space immune response monomeric IgA immunoglobulin complex secretory IgA immunoglobulin complex pentameric IgM immunoglobulin complex |
|
| 1418778_at |
Mcub |
mitochondrial calcium uniporter dominant negative beta subunit |
3 |
-129914959 |
NM_025779 |
66815 |
23 |
protein binding nucleoplasm mitochondrion mitochondrion mitochondrial inner membrane monoatomic ion transport calcium ion transport mitochondrial calcium ion transmembrane transport membrane calcium channel inhibitor activity calcium channel inhibitor activity calcium channel complex calcium import into the mitochondrion intracellular membrane-bounded organelle mitochondrial calcium ion homeostasis mitochondrial calcium ion homeostasis uniplex complex uniplex complex |
|
| 1455817_x_at |
Zxdb |
zinc finger, X-linked, duplicated B |
X |
94724568 |
AI661029 |
668166 |
11 |
transcription coregulator activity transcription coactivator activity nucleus nucleus regulation of transcription by RNA polymerase II metal ion binding C2H2 zinc finger domain binding |
|
| 1435002_at |
Zfp507 |
zinc finger protein 507 |
7 |
-35772345 |
BM249415 |
668501 |
22 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus regulation of DNA-templated transcription metal ion binding |
|
| 1454650_at |
Trim35 |
tripartite motif-containing 35 |
14 |
66297024 |
BQ175280 |
66854 |
32 |
protein binding nucleus cytoplasm cytoplasm apoptotic process zinc ion binding negative regulation of cell population proliferation protein ubiquitination transferase activity myeloid cell apoptotic process positive regulation of myeloid cell apoptotic process positive regulation of apoptotic process positive regulation of apoptotic process suppression of viral release by host innate immune response innate immune response negative regulation of mitotic cell cycle metal ion binding ubiquitin protein ligase activity |
|
| 1460672_at |
2410002F23Rik |
RIKEN cDNA 2410002F23 gene |
7 |
44246721 |
BC016099 |
668661 |
18 |
molecular_function cellular_component Golgi apparatus biological_process response to virus |
|
| 1429473_at |
Zfp869 |
zinc finger protein 869 |
8 |
-69705136, -69705137 |
AV292561 |
66869 |
18 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific nucleus nucleus regulation of transcription by RNA polymerase II retrotransposon silencing |
|
| 1417978_at |
Eif4e3 |
eukaryotic translation initiation factor 4E member 3 |
6 |
-99625136 |
BC027014 |
66892 |
23 |
RNA 7-methylguanosine cap binding RNA binding translation initiation factor activity translation initiation factor activity translation translational initiation translational initiation regulation of translation eukaryotic translation initiation factor 4F complex |
|
| 1451346_at |
Mtap |
methylthioadenosine phosphorylase |
4 |
89137369 |
BG075139 |
66902 |
38 |
catalytic activity nucleus nucleoplasm cytoplasm cytosol cytosol purine ribonucleoside salvage nucleoside metabolic process transferase activity glycosyltransferase activity pentosyltransferase activity S-methyl-5-thioadenosine phosphorylase activity S-methyl-5-thioadenosine phosphorylase activity L-methionine salvage from methylthioadenosine methylation |
00270 01100 |
| 1448689_at |
Rras2 |
related RAS viral (r-ras) oncogene 2 |
7 |
-114046781 |
NM_025846 |
66922 |
49 |
nucleotide binding GTPase activity GTPase activity protein binding GTP binding GTP binding intracellular anatomical structure Golgi apparatus plasma membrane plasma membrane signal transduction Ras protein signal transduction Ras protein signal transduction membrane cell migration hydrolase activity GDP binding Schwann cell migration positive regulation of Schwann cell migration |
04010 04530 04810 |
| 1423986_a_at |
Shisa5 |
shisa family member 5 |
9 |
109054865, 109038566, 109051156, 109051095, 109040413, 109052853 |
BC010238 |
66940 |
22 |
nucleus nuclear envelope endoplasmic reticulum endoplasmic reticulum apoptotic process membrane intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator WW domain binding intrinsic apoptotic signaling pathway by p53 class mediator |
04115 |
| 1439387_x_at |
Ctu2 |
cytosolic thiouridylase subunit 2 |
8 |
122476142 |
BB253397 |
66965 |
15 |
tRNA binding tRNA wobble uridine modification tRNA wobble position uridine thiolation cytoplasm cytosol tRNA processing sulfurtransferase activity protein-containing complex tRNA thio-modification |
04122 |
| 1417840_at |
Cep19 |
centrosomal protein 19 |
16 |
32099788 |
NM_025892 |
66994 |
18 |
spindle pole spindle pole molecular_function nucleoplasm cytoplasm centrosome centrosome centriole centriole cytoskeleton cilium cell projection organization microtubule anchoring at centrosome microtubule anchoring at centrosome ciliary basal body ciliary basal body cell projection cilium assembly vesicle targeting, trans-Golgi to periciliary membrane compartment vesicle targeting, trans-Golgi to periciliary membrane compartment |
|
| 1437862_at |
Rbm25 |
RNA binding motif protein 25 |
12 |
83635709, 83632242 |
AI159652 |
67039 |
31 |
regulation of alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome nucleic acid binding RNA binding mRNA binding mRNA binding nucleus cytoplasm mRNA processing apoptotic process RNA splicing nuclear speck regulation of apoptotic process |
03040 |
| 1431694_a_at |
Ctnnbip1 |
catenin beta interacting protein 1 |
4 |
149518240, 149545116 |
AK003595 |
67087 |
41 |
negative regulation of transcription by RNA polymerase II branching involved in ureteric bud morphogenesis regulation of vascular permeability involved in acute inflammatory response protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytosol cytosol beta-catenin binding beta-catenin binding beta-catenin binding anterior/posterior pattern specification Wnt signaling pathway negative regulation of Wnt signaling pathway negative regulation of Wnt signaling pathway negative regulation of Wnt signaling pathway beta-catenin destruction complex beta-catenin destruction complex negative regulation of protein-containing complex assembly negative regulation of protein binding negative regulation of DNA binding negative regulation of DNA-binding transcription factor activity negative regulation of DNA-binding transcription factor activity positive regulation of monocyte differentiation positive regulation of osteoblast differentiation negative regulation of smooth muscle cell proliferation negative regulation of transcription initiation by RNA polymerase II armadillo repeat domain binding negative regulation of mesenchymal cell proliferation negative regulation of canonical Wnt signaling pathway beta-catenin-ICAT complex |
04310 |
| 1423569_at |
Gatm |
glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
2 |
-122594472 |
AW108522 |
67092 |
43 |
kidney development mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial intermembrane space cytosol creatine metabolic process creatine biosynthetic process creatine biosynthetic process response to nutrient learning or memory response to organic substance muscle atrophy amidinotransferase activity amidinotransferase activity glycine amidinotransferase activity membrane transferase activity response to peptide hormone response to mercury ion positive regulation of cold-induced thermogenesis |
00260 00330 01100 |
| 1417777_at |
Ptgr1 |
prostaglandin reductase 1 |
4 |
-58965589 |
BC014865 |
67103 |
19 |
cytoplasm lipid metabolic process fatty acid metabolic process prostaglandin metabolic process prostaglandin metabolic process oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2-alkenal reductase [NAD(P)+] activity 2-alkenal reductase (NADP+) activity 13-prostaglandin reductase activity 15-oxoprostaglandin 13-oxidase activity 15-oxoprostaglandin 13-oxidase activity |
|
| 1452067_at |
Naaa |
N-acylethanolamine acid amidase |
5 |
-92257659 |
BI106821 |
67111 |
30 |
cytoplasm lysosome lysosome lipid metabolic process fatty acid metabolic process sphingosine metabolic process membrane lipid catabolic process hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds N-acylsphingosine amidohydrolase activity fatty acid amide hydrolase activity N-(long-chain-acyl)ethanolamine deacylase activity N-acylethanolamine metabolic process N-acylphosphatidylethanolamine metabolic process ceramidase activity DNA-binding transcription factor binding |
|
| 1433688_x_at |
Rpl14 |
ribosomal protein L14 |
9 |
120571516 |
BE993872 |
67115 |
44 |
cytoplasmic translation RNA binding RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome cytoplasm cytosol ribosome rRNA processing translation postsynaptic density cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome ribosomal large subunit biogenesis ribosomal large subunit biogenesis synapse synapse synapse presynapse postsynapse translation at presynapse translation at postsynapse ribonucleoprotein complex |
03010 |
| 1437878_s_at |
Ttc14 |
tetratricopeptide repeat domain 14 |
3 |
33800182 |
BB711506 |
67120 |
19 |
nucleic acid binding protein binding cellular_component biological_process |
|
| 1438037_at |
Herc6 |
hect domain and RLD 6 |
6 |
57580991 |
AW208668 |
67138 |
20 |
hematopoietic progenitor cell differentiation immune system process ubiquitin-protein transferase activity nucleoplasm cytoplasm cytoplasm cytosol ubiquitin-dependent protein catabolic process response to bacterium protein ubiquitination protein ubiquitination transferase activity cyclin binding innate immune response ubiquitin protein ligase activity ubiquitin protein ligase activity |
|
| 1430526_a_at |
Smarca2 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
19 |
26605159, 26748402, 26748164 |
AK011935 |
67155 |
131 |
nucleotide binding chromatin chromatin transcription cis-regulatory region binding DNA binding DNA binding chromatin binding transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm chromatin organization nucleosome assembly chromatin remodeling regulation of DNA-templated transcription regulation of transcription by RNA polymerase II nervous system development ATP-dependent activity, acting on DNA cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation SWI/SNF complex SWI/SNF complex hydrolase activity regulation of mitotic metaphase/anaphase transition negative regulation of cell growth brahma complex aortic smooth muscle cell differentiation histone binding intracellular membrane-bounded organelle intermediate filament cytoskeleton positive regulation of T cell differentiation negative regulation of cell differentiation positive regulation of cell differentiation positive regulation of myoblast differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II fibroblast proliferation negative regulation of fibroblast proliferation hematopoietic stem cell homeostasis regulation of G0 to G1 transition SWI/SNF superfamily-type complex npBAF complex npBAF complex nBAF complex nBAF complex bBAF complex GBAF complex ATP-dependent chromatin remodeler activity positive regulation of stem cell population maintenance regulation of G1/S transition of mitotic cell cycle positive regulation of double-strand break repair regulation of nucleotide-excision repair |
|
| 1417364_at |
Eef1g |
eukaryotic translation elongation factor 1 gamma |
19 |
8967040 |
AF321126 |
67160 |
42 |
translation elongation factor activity nucleus cytoplasm cytoplasm endoplasmic reticulum translation translational elongation translational elongation |
|
| 1453731_a_at |
Dram2 |
DNA-damage regulated autophagy modulator 2 |
3 |
106547797 |
AK015888 |
67171 |
20 |
photoreceptor inner segment molecular_function cytoplasm lysosome lysosome Golgi apparatus plasma membrane autophagy apoptotic process visual perception regulation of autophagy regulation of autophagy membrane apical plasma membrane intracellular membrane-bounded organelle photoreceptor cell maintenance photoreceptor cell maintenance photoreceptor cell maintenance |
|
| 1417062_at |
Armc10 |
armadillo repeat containing 10 |
5 |
21646005 |
NM_026034 |
67211 |
23 |
p53 binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane endoplasmic reticulum membrane positive regulation of growth rate negative regulation of apoptotic process DNA binding domain binding negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator |
|
| 1448829_at |
Smc6 |
structural maintenance of chromosomes 6 |
12 |
11265885, 11265885, 11265885 |
AV281575 |
67241 |
32 |
nucleotide binding DNA secondary structure binding telomere maintenance via recombination double-strand break repair via homologous recombination chromosome, centromeric region chromosome, telomeric region chromosome, telomeric region sex chromosome damaged DNA binding single-stranded DNA binding ATP binding nucleus nucleus nucleus nucleoplasm chromosome DNA repair double-strand break repair DNA recombination DNA damage response PML body PML body ATP hydrolysis activity Smc5-Smc6 complex Smc5-Smc6 complex Smc5-Smc6 complex ubiquitin protein ligase binding interchromatin granule site of double-strand break site of double-strand break negative regulation by host of viral genome replication positive regulation of chromosome segregation cellular senescence mitotic spindle pole |
|
| 1417372_a_at |
Peli1 |
pellino 1 |
11 |
21091323 |
BC016515 |
67245 |
81 |
protein polyubiquitination positive regulation of cytokine production ubiquitin-protein transferase activity protein binding nucleus regulation of Toll signaling pathway transferase activity positive regulation of B cell proliferation positive regulation of protein ubiquitination negative regulation of NF-kappaB transcription factor activity response to lipopolysaccharide response to lipopolysaccharide positive regulation of toll-like receptor 3 signaling pathway positive regulation of toll-like receptor 4 signaling pathway T cell proliferation T cell activation negative regulation of T cell proliferation positive regulation of canonical NF-kappaB signal transduction proteasome-mediated ubiquitin-dependent protein catabolic process response to dsRNA negative regulation of T cell activation positive regulation of B cell activation negative regulation of necroptotic process negative regulation of necroptotic process ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin protein ligase activity protein K63-linked ubiquitination protein K48-linked ubiquitination protein K48-linked ubiquitination protein K48-linked ubiquitination |
|
| 1451965_at |
LOC672450 |
V(kappa) gene product |
6 |
|
AY058908 |
672450 |
1 |
|
|
| 1416766_at |
Mtarc2 |
mitochondrial amidoxime reducing component 2 |
1 |
-184813065, -184813065 |
NM_133684 |
67247 |
29 |
catalytic activity mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial inner membrane peroxisome nitric oxide biosynthetic process nitrate reductase activity nitrate reductase activity membrane oxidoreductase activity oxidoreductase activity, acting on other nitrogenous compounds as donors molybdenum ion binding molybdenum ion binding pyridoxal phosphate binding nitrate metabolic process nitrate metabolic process molybdopterin cofactor binding molybdopterin cofactor binding cellular detoxification of nitrogen compound nitrite reductase activity |
|
| 1455500_at |
Rnf213 |
ring finger protein 213 |
11 |
119390098 |
AW556558 |
672511 |
46 |
nucleotide binding angiogenesis angiogenesis sprouting angiogenesis sprouting angiogenesis immune system process catalytic activity ubiquitin-protein transferase activity ubiquitin-protein transferase activity ATP binding nucleolus nucleolus cytoplasm lipid droplet cytosol cytosol ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process lipid metabolic process metabolic process protein ubiquitination transferase activity hydrolase activity ATP hydrolysis activity regulation of lipid metabolic process defense response to bacterium defense response to bacterium metal ion binding protein autoubiquitination ubiquitin protein ligase activity protein K63-linked ubiquitination xenophagy lipid ubiquitination lipid ubiquitination lipid droplet formation negative regulation of non-canonical Wnt signaling pathway negative regulation of non-canonical Wnt signaling pathway |
|
| 1417780_at |
Cers4 |
ceramide synthase 4 |
8 |
4493404 |
BB006809 |
67260 |
34 |
DNA binding endoplasmic reticulum lipid metabolic process membrane transferase activity sphingolipid biosynthetic process ceramide biosynthetic process ceramide biosynthetic process ceramide biosynthetic process sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity |
|
| 1429503_at |
Dipk1a |
divergent protein kinase domain 1A |
5 |
-107908041 |
AK013580 |
67266 |
21 |
molecular_function cellular_component endoplasmic reticulum biological_process membrane |
|
| 1418007_at |
Paxbp1 |
PAX3 and PAX7 binding protein 1 |
16 |
-91014036 |
BM932567 |
67367 |
27 |
mRNA splicing, via spliceosome DNA binding nucleus nucleus transcription by RNA polymerase II muscle organ development transcription factor binding regulation of skeletal muscle satellite cell proliferation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II histone methyltransferase binding positive regulation of myoblast proliferation |
|
| 1448960_at |
Cxxc5 |
CXXC finger 5 |
18 |
35830313, 35829787, 35854686 |
NM_133687 |
67393 |
42 |
negative regulation of transcription by RNA polymerase II DNA binding nucleus nucleus nucleoplasm cytoplasm cytosol zinc ion binding methyl-CpG binding methyl-CpG binding regulation of generation of precursor metabolites and energy sequence-specific DNA binding metal ion binding DNA-binding transcription factor binding |
|
| 1456739_x_at |
Armcx2 |
armadillo repeat containing, X-linked 2 |
X |
-134804141 |
BB392869 |
67416 |
19 |
molecular_function mitochondrion mitochondrion mitochondrial outer membrane biological_process membrane |
|
| 1417066_at |
Coq8a |
coenzyme Q8A |
1 |
-180165237, -180165237, -180166613 |
AK014605 |
67426 |
24 |
nucleotide binding ATP binding mitochondrion mitochondrion ubiquinone biosynthetic process ubiquinone biosynthetic process membrane kinase activity phosphorylation transferase activity ADP binding |
|
| 1429642_at |
Zfand4 |
zinc finger, AN1-type domain 4 |
6 |
116264218, 116266531 |
AK012639 |
67492 |
13 |
molecular_function cellular_component biological_process zinc ion binding metal ion binding |
|
| 1428821_at |
Agpat2 |
1-acylglycerol-3-phosphate O-acyltransferase 2 |
2 |
-26593056 |
AK010891 |
67512 |
35 |
positive regulation of cytokine production 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerol-3-phosphate O-acyltransferase activity endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process phosphatidic acid biosynthetic process phosphatidic acid biosynthetic process phospholipid biosynthetic process membrane transferase activity acyltransferase activity triglyceride biosynthetic process triglyceride biosynthetic process |
00561 00564 01100 04975 |
| 1436419_a_at |
1700097N02Rik |
RIKEN cDNA 1700097N02 gene |
17 |
-30622440 |
AA266367 |
67522 |
11 |
molecular_function cellular_component biological_process |
|
| 1435351_at |
Bend5 |
BEN domain containing 5 |
4 |
111415005 |
AA189197 |
67621 |
12 |
molecular_function DNA binding Golgi apparatus negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription |
|
| 1456446_at |
4930523C07Rik |
RIKEN cDNA 4930523C07 gene |
1 |
160044379, 160044379 |
BM246687 |
67647 |
9 |
molecular_function cellular_component biological_process |
|
| 1424802_a_at |
Luc7l3 |
LUC7-like 3 (S. cerevisiae) |
11 |
-94291072 |
AW536179 |
67684 |
25 |
DNA binding mRNA binding mRNA binding nucleus nucleoplasm U1 snRNP U1 snRNP mRNA splice site recognition mRNA splice site recognition mRNA processing RNA splicing nuclear speck U2-type prespliceosome |
|
| 1453939_x_at |
Gm9706 |
predicted gene 9706 |
17 |
|
AK019325 |
677168 |
7 |
|
|
| 1448747_at |
Fbxo32 |
F-box protein 32 |
15 |
-58175878 |
AF441120 |
67731 |
102 |
protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol cytosol negative regulation of cardiac muscle hypertrophy positive regulation of cardiac muscle cell apoptotic process response to electrical stimulus involved in regulation of muscle adaptation muscle atrophy response to denervation involved in regulation of muscle adaptation protein ubiquitination protein ubiquitination SCF ubiquitin ligase complex SCF ubiquitin ligase complex Z disc cellular response to dexamethasone stimulus |
|
| 1421457_a_at |
Samsn1 |
SAM domain, SH3 domain and nuclear localization signals, 1 |
16 |
-75858793 |
NM_023380 |
67742 |
24 |
phosphotyrosine residue binding phosphotyrosine residue binding negative regulation of adaptive immune response nucleus nucleus nucleus cytoplasm cytoplasm cytosol cell projection negative regulation of peptidyl-tyrosine phosphorylation negative regulation of peptidyl-tyrosine phosphorylation negative regulation of B cell activation negative regulation of B cell activation |
|
| 1437297_at |
Chd8 |
chromodomain helicase DNA binding protein 8 |
14 |
-52198150 |
BB409788 |
67772 |
84 |
negative regulation of transcription by RNA polymerase II nucleotide binding chromatin in utero embryonic development startle response p53 binding DNA binding DNA binding DNA binding chromatin binding chromatin binding chromatin binding helicase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm chromatin organization chromatin remodeling chromatin remodeling mRNA processing brain development brain development brain development beta-catenin binding Wnt signaling pathway hydrolase activity ATP hydrolysis activity negative regulation of Wnt signaling pathway protein-containing complex methylated histone binding social behavior histone binding histone binding histone binding negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase III digestive tract development digestive tract development digestive tract development prepulse inhibition armadillo repeat domain binding MLL1 complex MLL1 complex negative regulation of canonical Wnt signaling pathway negative regulation of canonical Wnt signaling pathway ATP-dependent chromatin remodeler activity ATP-dependent chromatin remodeler activity negative regulation of fibroblast apoptotic process |
04310 |
| 1418580_at |
Rtp4 |
receptor transporter protein 4 |
16 |
23609918 |
BC024872 |
67775 |
18 |
detection of chemical stimulus involved in sensory perception of bitter taste detection of chemical stimulus involved in sensory perception of bitter taste protein binding cytoplasm cytoplasm protein targeting to membrane protein targeting to membrane membrane olfactory receptor binding metal ion binding protein insertion into membrane defense response to virus |
|
| 1426221_at |
Vwa5a |
von Willebrand factor A domain containing 5A |
9 |
38718267 |
BC004727 |
67776 |
21 |
molecular_function extracellular matrix structural constituent nucleoplasm biological_process collagen-containing extracellular matrix |
|
| 1422678_at |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
7 |
-99153662 |
AK002443 |
67800 |
73 |
2-acylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity cytoplasm mitochondrion endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane lipid droplet lipid droplet cytosol glycerol metabolic process lipid metabolic process monoacylglycerol biosynthetic process diacylglycerol biosynthetic process O-acyltransferase activity positive regulation of triglyceride biosynthetic process membrane membrane transferase activity acyltransferase activity triglyceride biosynthetic process triglyceride biosynthetic process triglyceride biosynthetic process triglyceride biosynthetic process lipid storage lipid storage low-density lipoprotein particle clearance long-chain fatty-acyl-CoA metabolic process long-chain fatty-acyl-CoA metabolic process intracellular triglyceride homeostasis cholesterol homeostasis protein homodimerization activity intracellular membrane-bounded organelle positive regulation of gluconeogenesis negative regulation of fatty acid oxidation diacylglycerol metabolic process diacylglycerol metabolic process diacylglycerol metabolic process perinuclear region of cytoplasm retinol O-fatty-acyltransferase activity regulation of lipoprotein metabolic process fatty acid homeostasis fat pad development cellular response to oleic acid regulation of cholesterol metabolic process regulation of plasma lipoprotein particle levels perinuclear endoplasmic reticulum membrane |
00561 01100 04975 |
| 1456377_x_at |
Limd2 |
LIM domain containing 2 |
11 |
-106156253, -106156253, -106156253 |
AV010467 |
67803 |
23 |
molecular_function nucleus nucleoplasm cytoplasm cytosol plasma membrane biological_process actin cytoskeleton metal ion binding actin filament binding actin filament bundle assembly |
|
| 1460224_at |
Snx2 |
sorting nexin 2 |
18 |
53176291 |
BC006960 |
67804 |
31 |
epidermal growth factor receptor binding insulin receptor binding cytoplasm lysosome endosome endosome intracellular protein transport lipid binding endosome membrane endosome membrane protein transport membrane membrane retromer complex retromer, tubulation complex protein-containing complex early endosome to Golgi transport phosphatidylinositol binding phosphatidylinositol binding retrograde transport, endosome to Golgi identical protein binding protein homodimerization activity cell projection protein heterodimerization activity lamellipodium morphogenesis transferrin receptor binding leptin receptor binding |
|
| 1416527_at |
Rab32 |
RAB32, member RAS oncogene family |
10 |
-10545038 |
NM_026405 |
67844 |
41 |
nucleotide binding GTPase activity GTPase activity protein binding GTP binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane early endosome endoplasmic reticulum Golgi apparatus trans-Golgi network trans-Golgi network intracellular protein transport mitochondrion organization endomembrane system membrane vesicle-mediated transport antigen processing and presentation GTP-dependent protein binding cytoplasmic vesicle vesicle melanosome organization melanosome membrane endosome to melanosome transport AP-1 adaptor complex binding AP-3 adaptor complex binding BLOC-2 complex binding melanosome melanosome melanosome mitochondria-associated endoplasmic reticulum membrane phagocytic vesicle protein localization to membrane phagosome maturation melanosome assembly |
|
| 1452732_at |
Asprv1 |
aspartic peptidase, retroviral-like 1 |
6 |
86628173 |
AK004007 |
67855 |
19 |
aspartic-type endopeptidase activity aspartic-type endopeptidase activity proteolysis peptidase activity membrane protein processing protein processing hydrolase activity skin development |
|
| 1425684_at |
Akr1b10 |
aldo-keto reductase family 1, member B10 |
6 |
34384246 |
BB493454 |
67861 |
16 |
retinal dehydrogenase activity alditol:NADP+ 1-oxidoreductase activity estradiol 17-beta-dehydrogenase [NAD(P)] activity extracellular region mitochondrion mitochondrion mitochondrion lysosome cytosol cytosol alcohol dehydrogenase (NADP+) activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor geranylgeranyl reductase activity indanol dehydrogenase activity NADP-retinol dehydrogenase activity |
|
| 1424039_at |
Saraf |
store-operated calcium entry-associated regulatory factor |
8 |
34154578 |
BC022616 |
67887 |
22 |
endoplasmic reticulum endoplasmic reticulum membrane monoatomic ion transport calcium ion transport membrane endoplasmic reticulum-plasma membrane contact site regulation of store-operated calcium entry regulation of store-operated calcium entry |
|
| 1416939_at |
Ppa1 |
pyrophosphatase (inorganic) 1 |
10 |
61648620 |
NM_026438 |
67895 |
37 |
magnesium ion binding inorganic diphosphate phosphatase activity inorganic diphosphate phosphatase activity cytoplasm phosphate-containing compound metabolic process phosphate-containing compound metabolic process pyrophosphatase activity hydrolase activity metal ion binding |
00190 |
| 1433530_at |
Rpl41 |
ribosomal protein L41 |
10 |
-128548109 |
BI694945 |
67945 |
26 |
cytoplasmic translation structural constituent of ribosome cytoplasm cytosol ribosome translation cytosolic large ribosomal subunit cytosolic large ribosomal subunit ribonucleoprotein complex |
03010 |
| 1416431_at |
Tubb6 |
tubulin, beta 6 class V |
18 |
67390730 |
NM_026473 |
67951 |
43 |
nucleotide binding microtubule cytoskeleton organization mitotic cell cycle GTPase activity structural constituent of cytoskeleton structural constituent of cytoskeleton GTP binding GTP binding cytoplasm cytoplasm cytoskeleton microtubule microtubule microtubule-based process microtubule cytoskeleton intercellular bridge metal ion binding mitotic spindle |
04145 04540 |
| 1416713_at |
Tppp3 |
tubulin polymerization-promoting protein family member 3 |
8 |
-105467491 |
NM_026481 |
67971 |
32 |
microtubule bundle formation microtubule bundle formation cytoplasm cytoskeleton microtubule microtubule embryo implantation tubulin binding tubulin binding positive regulation of protein polymerization decidualization microtubule polymerization microtubule polymerization perinuclear region of cytoplasm microtubule bundle |
|
| 1417153_at |
Nacc2 |
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing |
2 |
-26055535, -26055535 |
NM_026495 |
67991 |
24 |
negative regulation of transcription by RNA polymerase II chromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding nucleus nucleolus mitochondrion negative regulation of cell population proliferation protein-containing complex localization protein homodimerization activity histone deacetylase binding protein-containing complex binding negative regulation of DNA-templated transcription protein homooligomerization positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage |
|
| 1417126_a_at |
Rpl22l1 |
ribosomal protein L22 like 1 |
3 |
28805507 |
NM_026517 |
68028 |
25 |
cytoplasmic translation RNA binding structural constituent of ribosome structural constituent of ribosome cytosol ribosome translation ribonucleoprotein complex |
03010 |
| 1449415_at |
Chd1l |
chromodomain helicase DNA binding protein 1-like |
3 |
-97560747 |
NM_026539 |
68058 |
28 |
nucleotide binding nucleotide binding DNA helicase activity ATP binding nucleus nucleus nucleoplasm chromosome cytosol plasma membrane DNA repair chromatin remodeling chromatin remodeling DNA damage response DNA damage response hydrolase activity ATP hydrolysis activity nucleosome binding site of double-strand break site of DNA damage histone reader activity ATP-dependent chromatin remodeler activity poly-ADP-D-ribose modification-dependent protein binding |
|
| 1423803_s_at |
Nop53 |
NOP53 ribosome biogenesis factor |
7 |
-15937835 |
BC017637 |
68077 |
23 |
ribosomal large subunit assembly ribosomal large subunit assembly negative regulation of transcription by RNA polymerase II fibrillar center regulation of protein phosphorylation p53 binding protein binding nucleus nucleoplasm nucleolus nucleolus nucleolus cytosol DNA repair rRNA processing DNA damage response mitotic G2 DNA damage checkpoint signaling 5S rRNA binding 5S rRNA binding negative regulation of protein-containing complex assembly negative regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process rDNA heterochromatin regulation of RIG-I signaling pathway ribosome biogenesis identical protein binding regulation of apoptotic process intracellular membrane-bounded organelle protein stabilization regulation of cell cycle negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction cellular response to hypoxia regulation of signal transduction by p53 class mediator negative regulation of signal transduction by p53 class mediator negative regulation of transcription of nucleolar large rRNA by RNA polymerase I protein localization to nucleolus positive regulation of protein K63-linked deubiquitination regulation of aerobic respiration protein localization to nucleoplasm |
|
| 1416536_at |
Pwwp3a |
PWWP domain containing 3A, DNA repair factor |
10 |
80226597 |
NM_023431 |
68114 |
17 |
nucleus nucleus nucleoplasm cytosol cytosol DNA repair DNA repair chromatin organization chromatin organization DNA damage response nucleosome binding nucleosome binding |
|
| 1455203_at |
A930003A15Rik |
RIKEN cDNA A930003A15 gene |
16 |
-19876567 |
BB522820 |
68162 |
10 |
molecular_function cellular_component biological_process |
|
| 1434581_at |
Mturn |
maturin, neural progenitor differentiation regulator homolog (Xenopus) |
6 |
54681623 |
BB167663 |
68235 |
19 |
molecular_function cytoplasm cytoplasm multicellular organism development regulation of signaling negative regulation of NF-kappaB transcription factor activity positive regulation of megakaryocyte differentiation positive regulation of megakaryocyte differentiation positive regulation of megakaryocyte differentiation positive regulation of JNK cascade neuron development positive regulation of ERK1 and ERK2 cascade |
|
| 1437309_a_at |
Rpa1 |
replication protein A1 |
11 |
-75300258 |
BB491281 |
68275 |
81 |
telomere maintenance double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination condensed chromosome condensed nuclear chromosome lateral element male germ cell nucleus in utero embryonic development nucleic acid binding DNA binding chromatin binding damaged DNA binding damaged DNA binding single-stranded DNA binding nucleus nucleus nucleoplasm nucleoplasm DNA replication factor A complex DNA replication factor A complex DNA replication DNA repair base-excision repair nucleotide-excision repair nucleotide-excision repair mismatch repair DNA recombination DNA damage response telomere maintenance via telomerase positive regulation of cell population proliferation PML body hemopoiesis protein localization to chromosome site of double-strand break single-stranded telomeric DNA binding metal ion binding homeostasis of number of cells within a tissue chromosome organization meiotic cell cycle meiotic cell cycle site of DNA damage G-rich strand telomeric DNA binding chromatin-protein adaptor activity protein localization to site of double-strand break |
03030 03420 03430 03440 |
| 1431705_a_at |
Mcoln2 |
mucolipin 2 |
3 |
146150173, 146149832 |
AK014467 |
68279 |
23 |
adaptive immune response immune system process monoatomic cation channel activity calcium channel activity lysosome endosome plasma membrane monoatomic ion transport calcium ion transport protein transport membrane membrane positive regulation of chemokine production monoatomic ion transmembrane transport identical protein binding innate immune response recycling endosome calcium ion transmembrane transport positive regulation of monocyte chemotactic protein-1 production positive regulation of macrophage inflammatory protein 1 alpha production positive regulation of chemokine (C-C motif) ligand 5 production NAADP-sensitive calcium-release channel activity macrophage migration neutrophil migration regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of chemokine (C-X-C motif) ligand 2 production |
|
| 1454893_at |
Entrep3 |
endosomal transmembrane epsin interactor 3 |
3 |
89183142 |
BB765852 |
68521 |
12 |
molecular_function cellular_component biological_process membrane WW domain binding |
|
| 1452353_at |
Gpr155 |
G protein-coupled receptor 155 |
2 |
-73341505 |
BB762731 |
68526 |
14 |
molecular_function lysosome lysosomal membrane lipid binding cholesterol binding membrane negative regulation of BMP signaling pathway cellular response to amino acid starvation intracellular signal transduction cognition transmembrane transport cellular response to cholesterol positive regulation of TORC1 signaling |
|
| 1435464_at |
Smim14 |
small integral membrane protein 14 |
5 |
-65446843, -65446843, -65446843, -65446843, -65446843, -65446843 |
BB701294 |
68552 |
21 |
blastocyst hatching molecular_function endoplasmic reticulum endoplasmic reticulum membrane |
|
| 1429072_at |
Col6a4 |
collagen, type VI, alpha 4 |
9 |
-105990317 |
AK003211 |
68553 |
24 |
collagen binding extracellular region collagen trimer cell adhesion extracellular matrix structural constituent conferring tensile strength extracellular matrix organization extracellular matrix protein-containing complex collagen-containing extracellular matrix |
04510 04512 04974 |
| 1428583_at |
Nufip2 |
nuclear FMR1 interacting protein 2 |
11 |
77686138 |
BQ176203 |
68564 |
32 |
RNA binding RNA binding nucleus nucleoplasm nucleoplasm cytoplasm cytosol ribosome cytoplasmic stress granule cytoplasmic stress granule nuclear body |
|
| 1429352_at |
Mocos |
molybdenum cofactor sulfurase |
18 |
24653690 |
AK003797 |
68591 |
16 |
catalytic activity cellular_component Mo-molybdopterin cofactor biosynthetic process Mo-molybdopterin cofactor sulfurase activity Mo-molybdopterin cofactor sulfurase activity transferase activity molybdenum ion binding pyridoxal phosphate binding molybdopterin cofactor biosynthetic process molybdopterin cofactor metabolic process molybdopterin cofactor metabolic process molybdenum cofactor sulfurtransferase activity |
|
| 1424254_at |
Ifitm1 |
interferon induced transmembrane protein 1 |
7 |
140967428, 140968075, 140968027 |
BC027285 |
68713 |
37 |
ossification somitogenesis immune system process molecular_function lysosome lysosomal membrane early endosome plasma membrane plasma membrane negative regulation of cell population proliferation response to virus response to virus anterior/posterior pattern specification membrane negative regulation of cell migration protein-containing complex response to type II interferon response to type II interferon response to interferon-alpha response to interferon-alpha response to interferon-beta response to interferon-beta negative regulation of viral genome replication negative regulation of viral genome replication innate immune response positive regulation of osteoblast differentiation negative regulation of viral entry into host cell negative regulation of viral entry into host cell negative regulation of viral entry into host cell defense response to virus defense response to virus type I interferon-mediated signaling pathway |
04662 |
| 1452646_at |
Trp53inp2 |
transformation related protein 53 inducible nuclear protein 2 |
2 |
155381855 |
AK003956 |
68728 |
22 |
autophagosome assembly autophagosome assembly osteoblast differentiation tissue homeostasis nucleus nucleus cytoplasm autophagosome autophagosome cytosol ubiquitin-dependent protein catabolic process autophagy protein localization macroautophagy cytoplasmic vesicle ubiquitin binding positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription negative regulation of protein localization |
|
| 1416617_at |
Acss1 |
acyl-CoA synthetase short-chain family member 1 |
2 |
-150618110 |
NM_080575 |
68738 |
37 |
nucleotide binding acetate-CoA ligase activity acetate-CoA ligase activity acetate-CoA ligase activity ATP binding mitochondrion mitochondrion mitochondrial matrix mitochondrial matrix acetyl-CoA biosynthetic process acetyl-CoA biosynthetic process acetyl-CoA biosynthetic process lipid metabolic process AMP binding ligase activity acetate biosynthetic process acetyl-CoA biosynthetic process from acetate propionate biosynthetic process propionate-CoA ligase activity |
00010 00620 00640 01100 |
| 1419599_s_at |
Ms4a6d |
membrane-spanning 4-domains, subfamily A, member 6D |
19 |
-11586605 |
NM_026835 |
68774 |
19 |
molecular_function trans-Golgi network trans-Golgi network plasma membrane cell surface receptor signaling pathway membrane |
|
| 1454857_at |
Rnf122 |
ring finger protein 122 |
8 |
31111826, 31115052 |
AW551457 |
68867 |
19 |
cytoplasm endoplasmic reticulum Golgi apparatus negative regulation of mitochondrial membrane potential membrane positive regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process metal ion binding protein autoubiquitination ubiquitin protein ligase activity |
|
| 1424509_at |
Cd177 |
CD177 antigen |
7 |
-24743982 |
BC027283 |
68891 |
21 |
protease binding immune system process integrin binding plasma membrane cell adhesion leukocyte cell-cell adhesion leukocyte cell-cell adhesion membrane regulation of endocytosis secretory granule membrane positive regulation of superoxide anion generation protein localization to cell surface positive regulation of neutrophil degranulation positive regulation of neutrophil degranulation plasma membrane raft plasma membrane raft innate immune response cell-cell junction maintenance cell-cell junction maintenance calcium-dependent protein binding tertiary granule membrane neutrophil extravasation cell-cell adhesion via plasma-membrane adhesion molecules cell-cell adhesion via plasma-membrane adhesion molecules regulation of integrin-mediated signaling pathway regulation of integrin-mediated signaling pathway |
|
| 1424337_at |
Snx15 |
sorting nexin 15 |
19 |
-6119398 |
BC016091 |
69024 |
19 |
nucleolus cytoplasm cytosol plasma membrane lipid binding protein transport membrane cytoplasmic vesicle phosphatidylinositol binding intracellular membrane-bounded organelle |
|
| 1422497_at |
Slc30a5 |
solute carrier family 30 (zinc transporter), member 5 |
13 |
-100802647 |
NM_022885 |
69048 |
28 |
Golgi membrane zinc ion transmembrane transporter activity zinc ion transmembrane transporter activity nucleoplasm nucleolus endoplasmic reticulum membrane Golgi apparatus Golgi apparatus plasma membrane GPI anchor biosynthetic process monoatomic ion transport monoatomic cation transport zinc ion transport intracellular zinc ion homeostasis intracellular zinc ion homeostasis monoatomic cation transmembrane transporter activity response to zinc ion ER to Golgi transport vesicle membrane antiporter activity membrane apical plasma membrane zinc efflux transmembrane transporter activity insulin processing secretory granule secretory granule membrane cytoplasmic vesicle cytoplasmic vesicle trans-Golgi network membrane metal ion binding transmembrane transport zinc ion import into organelle zinc ion import across plasma membrane zinc:proton antiporter activity zinc ion import into Golgi lumen zinc ion import into Golgi lumen Golgi cis cisterna membrane |
|
| 1434493_at |
Rbis |
ribosomal biogenesis factor |
3 |
-14606288, -14606288 |
BG092222 |
69126 |
15 |
molecular_function nucleus nucleoplasm nucleolus nucleolus cytosol ribosome biogenesis ribosome biogenesis |
|
| 1429889_at |
Fcmr |
Fc fragment of IgM receptor |
1 |
130865776 |
AK007714 |
69169 |
34 |
polymeric immunoglobulin binding IgM binding high-affinity IgM receptor activity immune system process immunoglobulin transcytosis in epithelial cells humoral immune response mediated by circulating immunoglobulin transmembrane signaling receptor activity protein binding lysosomal membrane plasma membrane plasma membrane plasma membrane external side of plasma membrane cell surface membrane early endosome membrane trans-Golgi network membrane trans-Golgi network membrane regulation of B cell receptor signaling pathway negative regulation of lymphocyte apoptotic process Fc receptor-mediated immune complex endocytosis inhibition of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of extrinsic apoptotic signaling pathway |
|
| 1428637_at |
Dyrk2 |
dual-specificity tyrosine phosphorylation regulated kinase 2 |
10 |
-118859348 |
AK007736 |
69181 |
27 |
ubiquitin ligase complex nucleotide binding magnesium ion binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol cytoskeleton protein phosphorylation apoptotic process smoothened signaling pathway kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation peptidyl-tyrosine phosphorylation manganese ion binding intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator positive regulation of glycogen biosynthetic process negative regulation of calcineurin-NFAT signaling cascade ribonucleoprotein complex |
|
| 1430612_at |
Mcemp1 |
mast cell expressed membrane protein 1 |
8 |
3665761 |
BB533148 |
69189 |
13 |
molecular_function cellular_component biological_process membrane identical protein binding |
|
| 1427837_at |
Igkv15-103 |
immunoglobulin kappa chain variable 15-103 |
6 |
|
U25103 |
692169 |
10 |
immunoglobulin production extracellular space immune response IgG immunoglobulin complex |
|
| 1427757_at |
Igk-V21 |
immunoglobulin kappa chain variable 21 (V21) |
6 |
|
D29670 |
692179 |
22 |
|
|
| 1423142_a_at |
Gtpbp4 |
GTP binding protein 4 |
13 |
-8972477 |
AI987834 |
69237 |
34 |
regulation of cyclin-dependent protein serine/threonine kinase activity nucleotide binding maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) RNA binding GTPase activity GTPase activity GTP binding nucleus nucleoplasm nucleolus nucleolus cytoplasm cytosol negative regulation of DNA replication negative regulation of cell population proliferation negative regulation of cell-cell adhesion negative regulation of cell migration negative regulation of protein ubiquitination nuclear membrane negative regulation of collagen binding ribosome biogenesis ribosomal large subunit biogenesis ribosomal large subunit biogenesis perinuclear region of cytoplasm protein stabilization preribosome binding |
03008 |
| 1435664_at |
Zfp397 |
zinc finger protein 397 |
18 |
23954687 |
AV342828 |
69256 |
17 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus nucleolus cytoplasm cytosol plasma membrane regulation of transcription by RNA polymerase II microtubule cytoskeleton protein homodimerization activity negative regulation of DNA-templated transcription protein heterodimerization activity |
|
| 1452798_s_at |
Mapk1ip1 |
mitogen-activated protein kinase 1 interacting protein 1 |
7 |
-138835817 |
AK009250 |
69546 |
19 |
cellular_component cytoplasm cytoskeleton multicellular organism development biological_process identical protein binding meiotic cell cycle |
|
| 1424921_at |
Bst2 |
bone marrow stromal cell antigen 2 |
8 |
-71534255 |
BC008532 |
69550 |
50 |
immune system process negative regulation of plasmacytoid dendritic cell cytokine production cytoplasm endosome multivesicular body Golgi apparatus Golgi apparatus plasma membrane metalloendopeptidase inhibitor activity metalloendopeptidase inhibitor activity response to virus response to virus cell surface cell surface cell surface membrane apical plasma membrane negative regulation of cell growth negative regulation of cell migration regulation of actin cytoskeleton organization response to type II interferon response to interferon-alpha response to interferon-beta identical protein binding protein homodimerization activity intracellular membrane-bounded organelle negative regulation of viral genome replication negative regulation of viral genome replication innate immune response innate immune response innate immune response defense response to virus defense response to virus side of membrane negative regulation of intracellular transport of viral material negative regulation of intracellular transport of viral material negative regulation of intracellular transport of viral material |
|
| 1435020_at |
Klhdc2 |
kelch domain containing 2 |
12 |
69296680 |
BE980167 |
69554 |
23 |
protein binding nucleus nucleoplasm nuclear body Cul2-RING ubiquitin ligase complex nuclear membrane proteasome-mediated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process via the C-end degron rule pathway ubiquitin ligase-substrate adaptor activity |
|
| 1449027_at |
Rhou |
ras homolog family member U |
8 |
123653928 |
AF378088 |
69581 |
25 |
G1/S transition of mitotic cell cycle nucleotide binding GTPase activity GTPase activity GTP binding GTP binding Golgi apparatus plasma membrane plasma membrane endocytosis cytoskeleton organization actin filament organization establishment or maintenance of cell polarity small GTPase-mediated signal transduction regulation of cell shape regulation of cell shape membrane Rac protein signal transduction protein kinase binding actin cytoskeleton organization Cdc42 protein signal transduction cell projection metal ion binding anchoring junction |
|
| 1452839_at |
Dph5 |
diphthamide biosynthesis 5 |
3 |
115888182 |
AK010475 |
69740 |
17 |
cellular_component methyltransferase activity transferase activity protein histidyl modification to diphthamide methylation |
|
| 1439956_at |
Ms4a6b |
membrane-spanning 4-domains, subfamily A, member 6B |
19 |
11518558 |
BE692425 |
69774 |
15 |
molecular_function trans-Golgi network trans-Golgi network plasma membrane cell surface receptor signaling pathway membrane |
|
| 1428947_at |
Mzb1 |
marginal zone B and B1 cell-specific protein 1 |
18 |
-35647264 |
AK008016 |
69816 |
22 |
positive regulation of immunoglobulin production protein binding extracellular region extracellular region extracellular region cytoplasm endoplasmic reticulum endoplasmic reticulum lumen positive regulation of cell population proliferation positive regulation of cell population proliferation regulation of B cell proliferation regulation of B cell proliferation integrin activation endoplasmic reticulum chaperone complex endoplasmic reticulum chaperone complex regulation of cell population proliferation regulation of insulin receptor signaling pathway |
|
| 1453047_at |
Tspo2 |
translocator protein 2 |
17 |
-48448434 |
AK011003 |
70026 |
12 |
endoplasmic reticulum endoplasmic reticulum plasma membrane cholesterol binding cholesterol binding membrane organelle membrane intracellular cholesterol transport lipid droplet organization enucleate erythrocyte differentiation import across plasma membrane 5-aminolevulinic acid import across plasma membrane 5-aminolevulinic acid transmembrane transporter activity |
|
| 1452197_at |
Smc4 |
structural maintenance of chromosomes 4 |
3 |
69004737 |
AV172948 |
70099 |
40 |
single strand break repair nucleotide binding chromosome, centromeric region condensed nuclear chromosome condensin complex condensin complex condensin complex condensin complex chromatin binding single-stranded DNA binding protein binding ATP binding nucleus chromosome cytoplasm cytosol cell cycle mitotic chromosome condensation meiotic chromosome condensation nuclear speck ATP hydrolysis activity chromosome condensation meiotic chromosome segregation chromosome organization cell division kinetochore organization positive regulation of chromosome segregation positive regulation of chromosome separation positive regulation of chromosome condensation |
|
| 1430878_at |
2210406H18Rik |
RIKEN cDNA 2210406H18 gene |
7 |
|
AV078837 |
70133 |
7 |
molecular_function cellular_component biological_process |
|
| 1428512_at |
Bhlhb9 |
basic helix-loop-helix domain containing, class B9 |
X |
135885850 |
AK012577 |
70237 |
25 |
nucleus nucleus cytoplasm cytosol learning or memory protein homodimerization activity negative regulation of neuron apoptotic process positive regulation of neurogenesis positive regulation of synapse assembly positive regulation of dendritic spine morphogenesis |
|
| 1440795_x_at |
Rabep2 |
rabaptin, RAB GTPase binding effector protein 2 |
7 |
126428766 |
BB259371 |
70314 |
25 |
GTPase activator activity cytoplasm endosome centrosome cytosol cytoskeleton endocytosis growth factor activity protein transport cell projection organization ciliary basal body cell projection intracellular membrane-bounded organelle intracellular membrane-bounded organelle regulation of cilium assembly |
|
| 1428572_at |
Basp1 |
brain abundant, membrane attached signal protein 1 |
15 |
-25363276 |
AK011545 |
70350 |
45 |
chromatin transcription cis-regulatory region binding transcription cis-regulatory region binding transcription corepressor activity transcription corepressor activity transcription corepressor activity protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytoplasm plasma membrane COP9 signalosome membrane nuclear matrix PML body nuclear speck protein domain specific binding cell junction cell projection negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription podocyte differentiation |
|
| 1423989_at |
Tecpr1 |
tectonin beta-propeller repeat containing 1 |
5 |
-144194441 |
BC025567 |
70381 |
22 |
autophagosome membrane autophagosome membrane nucleoplasm lysosome lysosomal membrane lysosomal membrane autophagy lipid binding membrane macroautophagy cytoplasmic vesicle phosphatidylinositol-3-phosphate binding phosphatidylinositol-3-phosphate binding protein-containing complex intracellular membrane-bounded organelle autophagosome maturation autophagosome maturation regulation of autophagosome maturation |
|
| 1419033_at |
Stk26 |
serine/threonine kinase 26 |
X |
50841370 |
AW556821 |
70415 |
26 |
Golgi membrane nucleotide binding magnesium ion binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding cytoplasm cytoplasm Golgi apparatus Golgi apparatus Golgi-associated vesicle cytosol protein phosphorylation protein phosphorylation apoptotic process cellular response to starvation membrane kinase activity phosphorylation apical plasma membrane transferase activity microvillus assembly negative regulation of cell migration negative regulation of cell migration stress-activated protein kinase signaling cascade response to hydrogen peroxide identical protein binding protein homodimerization activity regulation of apoptotic process protein autophosphorylation metal ion binding perinuclear region of cytoplasm cell periphery |
|
| 1429461_at |
Ints2 |
integrator complex subunit 2 |
11 |
-86210680 |
AK013101 |
70422 |
24 |
molecular_function nucleus cytoplasm membrane snRNA processing integrator complex integrator complex snRNA 3'-end processing |
|
| 1429383_at |
Csnk1g3 |
casein kinase 1, gamma 3 |
18 |
53862112 |
BM195380 |
70425 |
24 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus cytoplasm cytoplasm plasma membrane protein phosphorylation endocytosis signal transduction Wnt signaling pathway kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation positive regulation of canonical Wnt signaling pathway |
04340 |
| 1426623_a_at |
Arhgap17 |
Rho GTPase activating protein 17 |
7 |
-123279148 |
AV351061 |
70497 |
36 |
GTPase activator activity GTPase activator activity intracellular anatomical structure cytoplasm cytosol cytosol plasma membrane plasma membrane bicellular tight junction actin filament organization signal transduction membrane SH3 domain binding calcium-ion regulated exocytosis regulation of actin cytoskeleton organization regulation of Rac protein signal transduction positive regulation of GTPase activity anchoring junction |
|
| 1427050_at |
Txndc16 |
thioredoxin domain containing 16 |
14 |
-45134447 |
BC027108 |
70561 |
15 |
molecular_function extracellular region endoplasmic reticulum endoplasmic reticulum lumen biological_process |
|
| 1447774_x_at |
Prxl2a |
peroxiredoxin like 2A |
14 |
-40993734, -40993734, -40993734, -40993734, -40993734 |
AV332575 |
70564 |
26 |
extracellular region cytoplasm cytoplasm mitochondrion antioxidant activity antioxidant activity regulation of osteoclast differentiation |
|
| 1429413_at |
Cpm |
carboxypeptidase M |
10 |
117629499 |
AK017670 |
70574 |
25 |
carboxypeptidase activity metallocarboxypeptidase activity metallocarboxypeptidase activity extracellular space plasma membrane proteolysis peptide metabolic process peptidase activity metallopeptidase activity zinc ion binding membrane protein processing hydrolase activity metal ion binding side of membrane |
|
| 1447100_s_at |
Fam241a |
family with sequence similarity 241, member A |
3 |
-127869687 |
C80506 |
70617 |
15 |
molecular_function Golgi apparatus biological_process membrane intracellular membrane-bounded organelle |
|
| 1418401_a_at |
Dusp16 |
dual specificity phosphatase 16 |
6 |
-134715467 |
NM_130447 |
70686 |
40 |
phosphoprotein phosphatase activity nucleus nucleus nucleoplasm cytoplasm cytoplasm protein dephosphorylation protein tyrosine/threonine phosphatase activity JUN kinase binding dephosphorylation phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAP kinase tyrosine phosphatase activity peptidyl-tyrosine dephosphorylation negative regulation of MAPK cascade negative regulation of MAPK cascade negative regulation of JUN kinase activity MAPK export from nucleus mitogen-activated protein kinase p38 binding mitogen-activated protein kinase binding |
04010 |
| 1430570_at |
Kynu |
kynureninase |
2 |
43555324, 43555324, 43555324 |
AV227891 |
70789 |
16 |
nucleoplasm cytoplasm cytoplasm mitochondrion mitochondrion cytosol tryptophan catabolic process NAD biosynthetic process hydrolase activity pyridine nucleotide biosynthetic process tryptophan catabolic process to kynurenine tryptophan catabolic process to acetyl-CoA quinolinate biosynthetic process pyridoxal phosphate binding kynureninase activity kynureninase activity response to type II interferon response to vitamin B6 protein homodimerization activity anthranilate metabolic process anthranilate metabolic process 3-hydroxykynureninase activity |
00380 01100 |
| 1428727_at |
Cep192 |
centrosomal protein 192 |
18 |
67800106 |
AK014527 |
70799 |
25 |
pericentriolar material pericentriolar material cytoplasm cytoplasm centrosome centrosome centriole centriole microtubule nucleation mitotic spindle assembly checkpoint signaling centriole replication centriole replication response to bacterium protein kinase binding phosphatase binding regulation of centriole replication regulation of centrosome cycle regulation of establishment of protein localization protein localization to centrosome centrosome-templated microtubule nucleation centrosome-templated microtubule nucleation mitotic spindle assembly mitotic spindle assembly procentriole procentriole replication complex |
|
| 1433648_at |
Spag9 |
sperm associated antigen 9 |
11 |
94044129, 93996090 |
BM938614 |
70834 |
69 |
negative regulation of protein phosphorylation MAP-kinase scaffold activity MAP-kinase scaffold activity protein binding cytoplasm cytoplasm lysosome lysosomal membrane cytosol cytosol JUN kinase binding JUN kinase binding membrane vesicle-mediated transport kinesin binding kinesin binding signaling receptor complex adaptor activity positive regulation of cell migration lysosome localization centriolar satellite retrograde transport, endosome to Golgi identical protein binding positive regulation of MAPK cascade positive regulation of MAPK cascade negative regulation of neuron differentiation positive regulation of neuron differentiation striated muscle cell differentiation negative regulation of dendrite extension |
|
| 1452974_at |
Nol8 |
nucleolar protein 8 |
13 |
49653077 |
AK017551 |
70930 |
23 |
nucleic acid binding RNA binding RNA binding nucleus chromosome nucleolus nucleolus rRNA processing protein localization to nucleolus protein localization to nucleolus cellular response to leukemia inhibitory factor |
|
| 1424081_at |
Pcgf6 |
polycomb group ring finger 6 |
19 |
-47033616 |
BC016195 |
71041 |
41 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II protein binding nucleus nucleus chromatin remodeling regulation of transcription by RNA polymerase II protein domain specific binding PcG protein complex PcG protein complex PRC1 complex PRC1 complex negative regulation of DNA-templated transcription metal ion binding |
|
| 1439495_at |
Uvssa |
UV stimulated scaffold protein A |
5 |
33378695 |
BB476293 |
71101 |
14 |
RNA polymerase II complex binding RNA polymerase II complex binding nucleoplasm chromosome chromosome DNA repair transcription-coupled nucleotide-excision repair transcription-coupled nucleotide-excision repair DNA damage response response to UV response to UV protein ubiquitination |
|
| 1429031_at |
Zfp626 |
zinc finger protein 626 |
7 |
27807195 |
BM938256 |
71163 |
14 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II |
|
| 1453119_at |
Otud1 |
OTU domain containing 1 |
2 |
19657730 |
BB530087 |
71198 |
24 |
cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity cellular_component proteolysis peptidase activity cysteine-type peptidase activity hydrolase activity protein K63-linked deubiquitination protein K63-linked deubiquitination |
|
| 1431143_x_at |
Aifm2 |
apoptosis-inducing factor, mitochondrion-associated 2 |
10 |
61715262, 61720648, 61715262 |
AK017403 |
71361 |
31 |
DNA binding electron-transferring-flavoprotein dehydrogenase activity electron-transferring-flavoprotein dehydrogenase activity protein binding nucleus cytoplasm cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial outer membrane lipid droplet cytosol plasma membrane ubiquinone metabolic process apoptotic mitochondrial changes apoptotic mitochondrial changes membrane oxidoreductase activity oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor mitochondrial membrane vitamin K metabolic process positive regulation of apoptotic process positive regulation of apoptotic process flavin adenine dinucleotide binding flavin adenine dinucleotide binding negative regulation of ferroptosis regulation of cellular response to oxidative stress cellular detoxification |
|
| 1436925_at |
Foxn3 |
forkhead box N3 |
12 |
-99195093 |
AV228812 |
71375 |
35 |
cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity nucleus nucleus regulation of DNA-templated transcription regulation of DNA-templated transcription cell cycle mitotic G2 DNA damage checkpoint signaling sequence-specific DNA binding negative regulation of DNA-templated transcription craniofacial suture morphogenesis |
|
| 1427384_at |
Chd6 |
chromodomain helicase DNA binding protein 6 |
2 |
-160946977 |
BB529459 |
71389 |
25 |
nucleotide binding chromatin transcription coregulator binding DNA binding DNA binding chromatin binding helicase activity ATP binding nucleus nucleus nucleoplasm chromatin organization chromatin remodeling ATP-dependent activity, acting on DNA regulation of gene expression hydrolase activity ATP hydrolysis activity histone binding cell redox homeostasis positive regulation of transcription by RNA polymerase II ATP-dependent chromatin remodeler activity ATP-dependent chromatin remodeler activity |
|
| 1428579_at |
Fmnl2 |
formin-like 2 |
2 |
52857867 |
AK017338 |
71409 |
27 |
actin binding cytosol cytoskeleton organization regulation of cell shape cellular component organization cell migration regulation of cell morphogenesis actin cytoskeleton organization cortical actin cytoskeleton organization cortical actin cytoskeleton organization small GTPase binding actin filament binding |
|
| 1428773_s_at |
Bcor |
BCL6 interacting corepressor |
X |
-12036737, -12036737, -12134453 |
AK018370 |
71458 |
58 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding blastocyst hatching transcription corepressor activity transcription corepressor activity transcription corepressor activity ubiquitin-protein transferase activity protein binding nucleus nucleus nucleus nucleoplasm chromatin organization heat shock protein binding histone deacetylase binding BCOR complex DNA-binding transcription factor binding |
|
| 1436898_at |
Sfpq |
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) |
4 |
127021300, 127021300 |
BI738328 |
71514 |
95 |
negative regulation of transcription by RNA polymerase II alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome double-strand break repair via homologous recombination chromatin transcription cis-regulatory region binding activation of innate immune response immune system process nucleic acid binding DNA binding chromatin binding RNA binding RNA binding protein binding nucleus nucleus nucleoplasm cytoplasm DNA repair chromatin remodeling regulation of DNA-templated transcription mRNA processing DNA damage response RNA splicing nuclear matrix dendrite dendrite cytoplasm paraspeckles paraspeckles regulation of circadian rhythm negative regulation of circadian rhythm protein homodimerization activity histone deacetylase binding innate immune response positive regulation of sister chromatid cohesion negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II rhythmic process chromosome organization regulation of cell cycle RNA polymerase II transcription regulator complex dendritic transport of messenger ribonucleoprotein complex dendritic transport of messenger ribonucleoprotein complex dendritic transport of messenger ribonucleoprotein complex positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway |
|
| 1429387_at |
Grap |
GRB2-related adaptor protein |
11 |
61653320 |
AK018457 |
71520 |
18 |
phosphotyrosine residue binding epidermal growth factor receptor binding nucleoplasm cytoplasm plasma membrane signal transduction COP9 signalosome membrane regulation of MAPK cascade synapse |
|
| 1452952_at |
Fam217b |
family with sequence similarity 217, member B |
2 |
178414533 |
AK018518 |
71532 |
9 |
molecular_function nucleoplasm cytosol biological_process |
|
| 1426276_at |
Ifih1 |
interferon induced with helicase C domain 1 |
2 |
-62595792 |
AY075132 |
71586 |
168 |
nucleotide binding immune system process DNA binding RNA binding RNA helicase activity double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding helicase activity protein binding ATP binding nucleus cytoplasm cytoplasm cytoplasm mitochondrion zinc ion binding zinc ion binding response to virus response to virus hydrolase activity ATP hydrolysis activity protein sumoylation protein domain specific binding interferon-beta production positive regulation of interferon-alpha production positive regulation of interferon-beta production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production pattern recognition receptor activity MDA-5 signaling pathway MDA-5 signaling pathway identical protein binding ribonucleoprotein complex binding negative regulation of viral genome replication innate immune response metal ion binding protein complex oligomerization defense response to virus type I interferon-mediated signaling pathway positive regulation of response to cytokine stimulus cellular response to exogenous dsRNA antiviral innate immune response antiviral innate immune response |
04622 |
| 1428509_at |
Myo1e |
myosin IE |
9 |
70207349 |
AK018649 |
71602 |
55 |
microfilament motor activity nucleotide binding vasculogenesis in utero embryonic development kidney development glomerular filtration cytoskeletal motor activity actin binding calmodulin binding ATP binding cytoplasm cytoplasm cytoskeleton plasma membrane microvillus brush border adherens junction nitrogen compound metabolic process endocytosis endocytosis actin filament organization lipid binding actin cytoskeleton myosin complex ATP hydrolysis activity hemopoiesis cytoplasmic vesicle cuticular plate glomerulus development glomerular basement membrane development protein-containing complex phosphatidylinositol binding post-embryonic hemopoiesis protein-containing complex binding clathrin-coated endocytic vesicle platelet-derived growth factor receptor signaling pathway actin filament binding actin filament binding anchoring junction podocyte development |
|
| 1429055_at |
Shtn1 |
shootin 1 |
19 |
-58973357 |
BB559293 |
71653 |
31 |
protein binding cytoplasm cytoplasm cytoskeleton microtubule microtubule associated complex substrate-dependent cell migration, cell extension Ras protein signal transduction multicellular organism development axonogenesis microtubule cytoskeleton kinesin binding lamellipodium filopodium axon growth cone growth cone cell leading edge cell leading edge Cdc42 protein signal transduction netrin-activated signaling pathway identical protein binding cell projection perikaryon axonal growth cone axonal growth cone axonal growth cone positive regulation of axon extension perinuclear region of cytoplasm neuron projection morphogenesis neuron projection morphogenesis cell adhesion molecule binding actin filament binding membrane depolarization cytoplasmic actin-based contraction involved in cell motility endoplasmic reticulum polarization actin filament bundle retrograde transport regulation of establishment of cell polarity regulation of establishment of cell polarity regulation of neuron migration positive regulation of neuron migration positive regulation of neuron migration positive regulation of neuron migration |
|
| 1424250_a_at |
Arhgef3 |
Rho guanine nucleotide exchange factor 3 |
14 |
27238009, 27143992, 27361388, 27336036 |
BC012262 |
71704 |
32 |
guanyl-nucleotide exchange factor activity cytoplasm positive regulation of Rho protein signal transduction intracellular signal transduction |
|
| 1424524_at |
Dram1 |
DNA-damage regulated autophagy modulator 1 |
10 |
-88322803 |
BC021433 |
71712 |
22 |
molecular_function cytoplasm lysosome lysosome autophagy apoptotic process regulation of autophagy regulation of autophagy membrane |
|
| 1435137_s_at |
1200015M12Rik |
RIKEN cDNA 1200015M12 gene |
19 |
|
BB119177 |
71739 |
9 |
molecular_function cellular_component biological_process |
|
| 1428449_at |
Gtf3c2 |
general transcription factor IIIC, polypeptide 2, beta |
5 |
-31156005 |
AV297256 |
71752 |
29 |
transcription factor TFIIIC complex transcription factor TFIIIC complex RNA polymerase III general transcription initiation factor activity DNA binding nucleoplasm transcription by RNA polymerase III transcription by RNA polymerase III |
|
| 1428385_at |
Marchf8 |
membrane associated ring-CH-type finger 8 |
6 |
116338021 |
AK005032 |
71779 |
25 |
protein polyubiquitination protein polyubiquitination adaptive immune response immune system process antigen processing and presentation of peptide antigen via MHC class II antigen processing and presentation of peptide antigen via MHC class II ubiquitin-protein transferase activity ubiquitin-protein transferase activity cytoplasm lysosome lysosome endosome endoplasmic reticulum Golgi apparatus immune response zinc ion binding membrane protein ubiquitination transferase activity cytoplasmic vesicle early endosome membrane late endosome membrane MHC protein binding MHC class II protein binding negative regulation of MHC class II biosynthetic process metal ion binding ubiquitin protein ligase activity ubiquitin protein ligase activity |
|
| 1452316_at |
Ints12 |
integrator complex subunit 12 |
3 |
133091854 |
AK003874 |
71793 |
21 |
molecular_function nucleus snRNA processing integrator complex integrator complex snRNA 3'-end processing metal ion binding |
|
| 1429274_at |
Lypd6b |
LY6/PLAUR domain containing 6B |
2 |
49787682 |
AK009282 |
71897 |
18 |
cellular_component plasma membrane membrane acetylcholine receptor regulator activity acetylcholine receptor regulator activity side of membrane |
|
| 1452257_at |
Bdh1 |
3-hydroxybutyrate dehydrogenase, type 1 |
16 |
31428752, 31422296 |
BF322712 |
71911 |
43 |
catalytic activity 3-hydroxybutyrate dehydrogenase activity 3-hydroxybutyrate dehydrogenase activity phospholipid binding mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane lipid metabolic process metabolic process steroid metabolic process membrane oxidoreductase activity intracellular membrane-bounded organelle |
00072 00650 01100 |
| 1431055_a_at |
Snx10 |
sorting nexin 10 |
6 |
51524259, 51545292, 51524083, 51544522, 51523902 |
AK010399 |
71982 |
37 |
gastric acid secretion 1-phosphatidylinositol binding nucleus nucleus cytoplasm endosome endosome endoplasmic reticulum endoplasmic reticulum centrosome cytoskeleton intracellular protein transport endocytosis endosome organization lipid binding protein transport membrane vesicle organization cellular homeostasis cell projection organization secretory granule osteoclast differentiation extrinsic component of endosome membrane phosphatidylinositol binding bone mineralization involved in bone maturation tooth eruption bone resorption bone remodeling ATPase binding establishment of localization in cell calcium ion homeostasis cilium assembly cilium assembly protein localization to cilium protein localization to centrosome apical cytoplasm ruffle assembly phosphatidylinositol phosphate binding cellular response to leukemia inhibitory factor |
|
| 1436759_x_at |
Cnn3 |
calponin 3, acidic |
3 |
121426540 |
AV172168 |
71994 |
47 |
actin binding calmodulin binding cytosol actin filament organization microtubule binding actin cytoskeleton actin cytoskeleton dendrite actomyosin structure organization neuronal cell body dendritic spine actin filament binding postsynapse glutamatergic synapse |
|
| 1433833_at |
Fndc3b |
fibronectin type III domain containing 3B |
3 |
-27416134 |
BG064539 |
72007 |
35 |
endoplasmic reticulum fibroblast migration membrane substrate adhesion-dependent cell spreading positive regulation of fat cell differentiation positive regulation of fat cell differentiation negative regulation of osteoblast differentiation positive regulation of fibroblast proliferation type II pneumocyte differentiation |
|
| 1419307_at |
Tnfrsf13c |
tumor necrosis factor receptor superfamily, member 13c |
15 |
-82221741 |
NM_028075 |
72049 |
108 |
B cell homeostasis adaptive immune response immune system process germinal center formation positive regulation of germinal center formation external side of plasma membrane external side of plasma membrane membrane positive regulation of B cell proliferation positive regulation of B cell proliferation T cell costimulation T cell costimulation T cell costimulation B cell costimulation B cell costimulation positive regulation of type II interferon production tumor necrosis factor-mediated signaling pathway signaling receptor activity T cell proliferation T cell proliferation B cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation regulation of immune response |
04060 04672 05340 |
| 1454785_at |
Dusp11 |
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) |
6 |
-85942268 |
BE951717 |
72102 |
18 |
fibrillar center RNA binding polynucleotide 5'-phosphatase activity polynucleotide 5'-phosphatase activity phosphoprotein phosphatase activity protein tyrosine phosphatase activity nucleus nucleoplasm protein dephosphorylation protein tyrosine/serine/threonine phosphatase activity dephosphorylation nuclear speck hydrolase activity phosphatase activity intercellular bridge |
|
| 1451079_at |
Adpgk |
ADP-dependent glucokinase |
9 |
59291571 |
BC021526 |
72141 |
30 |
extracellular region endoplasmic reticulum endoplasmic reticulum carbohydrate metabolic process glucose metabolic process glucose metabolic process glucose metabolic process glycolytic process kinase activity phosphorylation transferase activity phosphotransferase activity, alcohol group as acceptor ADP-specific glucokinase activity ADP-specific glucokinase activity ADP-specific glucokinase activity metal ion binding |
00010 01100 |
| 1428517_at |
Wdfy3 |
WD repeat and FYVE domain containing 3 |
5 |
-101832952 |
AK012075 |
72145 |
50 |
autophagosome membrane beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity 1-phosphatidylinositol binding nucleus nuclear envelope nucleoplasm nucleolus cytoplasm cytoplasm autophagosome cytosol plasma membrane autophagy multicellular organism development lipid binding membrane inclusion body PML body Atg12-Atg5-Atg16 complex aggrephagy aggrephagy cell projection metal ion binding |
|
| 1428357_at |
Tdrp |
testis development related protein |
8 |
-13952007, -13952007 |
AK011462 |
72148 |
22 |
molecular_function nucleus nucleus cytoplasm cytosol cytosol spermatogenesis spermatogenesis intracellular membrane-bounded organelle |
|
| 1424444_a_at |
1600014C10Rik |
RIKEN cDNA 1600014C10 gene |
7 |
38183786, 38183216 |
BC019834 |
72244 |
15 |
molecular_function cytoplasm mitochondrion endoplasmic reticulum cytosol autophagy apoptotic process response to oxidative stress membrane mitochondrial membrane mitochondrial calcium ion homeostasis |
|
| 1433768_at |
Palld |
palladin, cytoskeletal associated protein |
8 |
-61514703, -61511430, -61511430, -61511430 |
BG071905 |
72333 |
61 |
stress fiber stress fiber ruffle podosome keratinocyte development epithelial cell morphogenesis actin binding nucleus nucleus cytoplasm mitochondrion cytosol cytoskeleton cytoskeleton actin filament actin filament plasma membrane plasma membrane focal adhesion focal adhesion homophilic cell adhesion via plasma membrane adhesion molecules axon guidance receptor activity cytoskeletal protein binding actin cytoskeleton cell migration Z disc Z disc lamellipodium actin cytoskeleton organization filopodium axon axon growth cone cell projection neuronal cell body neuronal cell body axonal growth cone synapse organization excitatory synapse anchoring junction |
|
| 1424029_at |
Tspyl4 |
TSPY-like 4 |
10 |
34297420 |
BC017540 |
72480 |
17 |
chromatin molecular_function chromatin binding nucleus nucleus nucleosome assembly biological_process histone binding |
|
| 1428389_s_at |
Wdr43 |
WD repeat domain 43 |
17 |
71616214 |
AK012043 |
72515 |
25 |
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) chromatin RNA polymerase II complex binding fibrillar center transcription elongation factor activity RNA binding protein binding nucleus nucleoplasm nucleolus nucleolus nucleolus rRNA processing small-subunit processome regulation of transcription elongation by RNA polymerase II ribosome biogenesis ribosomal small subunit biogenesis positive regulation of transcription by RNA polymerase I regulation of stem cell population maintenance positive regulation of rRNA processing |
03008 |
| 1428768_at |
Pan3 |
PAN3 poly(A) specific ribonuclease subunit |
5 |
147430155 |
AK012409 |
72587 |
23 |
nucleotide binding nuclear-transcribed mRNA poly(A) tail shortening nuclear-transcribed mRNA poly(A) tail shortening deadenylation-dependent decapping of nuclear-transcribed mRNA P-body P-body RNA binding poly(A)-specific ribonuclease activity protein kinase activity protein binding ATP binding nucleus cytoplasm mRNA processing protein phosphorylation protein targeting poly(A) binding positive regulation of cytoplasmic mRNA processing body assembly positive regulation of cytoplasmic mRNA processing body assembly PAN complex PAN complex metal ion binding |
03018 |
| 1428810_at |
2700097O09Rik |
RIKEN cDNA 2700097O09 gene |
12 |
-55045660 |
AK012621 |
72658 |
20 |
methyltransferase activity |
|
| 1430195_at |
2810043O03Rik |
RIKEN cDNA 2810043O03 gene |
9 |
|
BF662697 |
72697 |
8 |
molecular_function cellular_component biological_process |
|
| 1426223_at |
Ttc39c |
tetratricopeptide repeat domain 39C |
18 |
12643532 |
BC020021 |
72747 |
17 |
molecular_function cellular_component otolith morphogenesis cilium assembly |
|
| 1429096_at |
2810455D13Rik |
RIKEN cDNA 2810455D13 gene |
19 |
|
AK013353 |
72810 |
7 |
molecular_function cellular_component biological_process |
|
| 1426985_s_at |
Fam76b |
family with sequence similarity 76, member B |
9 |
13827715 |
AV337692 |
72826 |
19 |
nucleus nuclear speck nuclear speck |
|
| 1438969_x_at |
Dhx30 |
DExH-box helicase 30 |
9 |
-110084318, -110084318, -110084318 |
BB105391 |
72831 |
35 |
nucleotide binding G-quadruplex RNA binding nucleic acid binding DNA helicase activity chromatin binding RNA binding RNA helicase activity RNA helicase activity RNA helicase activity double-stranded RNA binding helicase activity ATP binding intracellular anatomical structure nucleus cytoplasm cytoplasm cytoplasm mitochondrion cytosol central nervous system development hydrolase activity ribonucleoprotein granule ribosome biogenesis mitochondrial nucleoid mitochondrial large ribosomal subunit assembly |
|
| 1435445_at |
Ccnt2 |
cyclin T2 |
1 |
127774163 |
AV377237 |
72949 |
28 |
transcription coactivator binding chromatin binding protein binding nucleus nucleus nucleoplasm cytoplasm cytosol plasma membrane regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cell cycle skeletal muscle tissue development cyclin/CDK positive transcription elongation factor complex cyclin/CDK positive transcription elongation factor complex cyclin-dependent protein serine/threonine kinase regulator activity early viral transcription late viral transcription protein kinase binding positive regulation of DNA-templated transcription, elongation positive regulation of transcription elongation by RNA polymerase II positive regulation of transcription by RNA polymerase II perinuclear region of cytoplasm regulation of muscle cell differentiation cell division cyclin-dependent protein serine/threonine kinase activator activity RNA polymerase binding 7SK snRNA binding |
|
| 1431050_at |
Rps6ka5 |
ribosomal protein S6 kinase, polypeptide 5 |
12 |
-100548439 |
BE291900 |
73086 |
109 |
nucleotide binding magnesium ion binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding ATP binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of DNA-templated transcription protein phosphorylation protein phosphorylation inflammatory response kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation histone H3S10 kinase activity intracellular signal transduction intracellular signal transduction post-translational protein modification post-translational protein modification histone H3S28 kinase activity histone H3S28 kinase activity histone H2AS1 kinase activity negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of NF-kappaB transcription factor activity interleukin-1-mediated signaling pathway regulation of postsynapse organization regulation of postsynapse organization |
04010 04722 05219 |
| 1429954_at |
Clec4a3 |
C-type lectin domain family 4, member a3 |
6 |
122952514, 122952643 |
AK014135 |
73149 |
12 |
calcium ion binding mannose binding external side of plasma membrane carbohydrate binding carbohydrate binding antifungal innate immune response |
|
| 1455433_at |
Zfp942 |
zinc finger protein 942 |
17 |
-21926962 |
BM241540 |
73233 |
14 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II |
|
| 1434675_at |
Zfp763 |
zinc finger protein 763 |
17 |
-33016863 |
BB442939 |
73451 |
15 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II |
|
| 1454923_at |
Iws1 |
IWS1, SUPT6 interacting protein |
18 |
32067733 |
BQ175964 |
73473 |
22 |
molecular_function nucleus nucleus nucleoplasm chromatin remodeling mRNA processing RNA splicing regulation of mRNA export from nucleus poly(A)+ mRNA export from nucleus regulation of mRNA processing mRNA transport transcription elongation-coupled chromatin remodeling |
|
| 1450234_at |
Ms4a6c |
membrane-spanning 4-domains, subfamily A, member 6C |
19 |
11469367, 11469367 |
AF237910 |
73656 |
14 |
trans-Golgi network trans-Golgi network plasma membrane cell surface receptor signaling pathway membrane |
|
| 1451649_a_at |
Wdr75 |
WD repeat domain 75 |
1 |
45795165 |
BC004071 |
73674 |
24 |
RNA binding nucleus nucleolus nucleolus rRNA processing small-subunit processome ribosome biogenesis ribosomal small subunit biogenesis positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase I positive regulation of rRNA processing positive regulation of rRNA processing |
03008 |
| 1429396_at |
Atg16l2 |
autophagy related 16 like 2 |
7 |
-101289615 |
AK010773 |
73683 |
26 |
autophagosome assembly autophagosome assembly autophagosome membrane protein binding nucleoplasm cytoplasm cytosol protein transport macroautophagy phagophore assembly site membrane phagophore assembly site membrane Atg12-Atg5-Atg16 complex Atg12-Atg5-Atg16 complex Atg12-Atg5-Atg16 complex negative stranded viral RNA replication negative stranded viral RNA replication |
|
| 1428781_at |
Dmkn |
dermokine |
7 |
30763755, 30776404, 30763757 |
BI452905 |
73712 |
23 |
molecular_function extracellular region extracellular space extracellular space cell differentiation cornified envelope assembly cornified envelope assembly |
|
| 1436506_a_at |
Snhg6 |
small nucleolar RNA host gene 6 |
1 |
-9942024 |
AW988981 |
73824 |
19 |
molecular_function cellular_component biological_process |
|
| 1435040_at |
Irak3 |
interleukin-1 receptor-associated kinase 3 |
10 |
-120141647, -120141647 |
AV228493 |
73914 |
89 |
nucleotide binding magnesium ion binding magnesium ion binding positive regulation of cytokine production negative regulation of cytokine-mediated signaling pathway protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding ATP binding nucleus nucleus nucleus cytoplasm cytoplasm cytoplasm plasma membrane protein phosphorylation protein phosphorylation apoptotic process signal transduction Toll signaling pathway response to virus positive regulation of macrophage tolerance induction negative regulation of macrophage cytokine production cytokine-mediated signaling pathway protein kinase binding negative regulation of NF-kappaB transcription factor activity response to peptidoglycan response to lipopolysaccharide negative regulation of interleukin-12 production negative regulation of interleukin-12 production negative regulation of interleukin-12 production negative regulation of interleukin-6 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production negative regulation of tumor necrosis factor production negative regulation of tumor necrosis factor production negative regulation of toll-like receptor signaling pathway intracellular signal transduction negative regulation of protein catabolic process negative regulation of protein catabolic process protein homodimerization activity regulation of apoptotic process negative regulation of protein-containing complex disassembly regulation of protein-containing complex disassembly response to exogenous dsRNA negative regulation of MAP kinase activity negative regulation of MAP kinase activity negative regulation of MAP kinase activity negative regulation of innate immune response protein autophosphorylation protein heterodimerization activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity interleukin-1-mediated signaling pathway interleukin-1-mediated signaling pathway interleukin-1-mediated signaling pathway response to interleukin-1 cellular response to lipopolysaccharide |
04210 04722 |
| 1434468_at |
Otud4 |
OTU domain containing 4 |
8 |
79639675 |
BM238914 |
73945 |
29 |
immune system process cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity nucleus cytoplasm cytosol proteolysis peptidase activity cysteine-type peptidase activity protein deubiquitination hydrolase activity negative regulation of toll-like receptor signaling pathway negative regulation of toll-like receptor signaling pathway negative regulation of toll-like receptor signaling pathway innate immune response molecular adaptor activity K63-linked deubiquitinase activity K63-linked deubiquitinase activity K63-linked deubiquitinase activity protein K63-linked deubiquitination protein K63-linked deubiquitination protein K48-linked deubiquitination positive regulation of DNA demethylation regulation of protein K48-linked deubiquitination regulation of protein K48-linked deubiquitination negative regulation of interleukin-1-mediated signaling pathway negative regulation of interleukin-1-mediated signaling pathway negative regulation of interleukin-1-mediated signaling pathway |
|
| 1429960_at |
4930438A08Rik |
RIKEN cDNA 4930438A08 gene |
11 |
58274827 |
BB775376 |
73988 |
8 |
L-amino-acid oxidase activity cellular_component amino acid catabolic process polyamine oxidase activity |
|
| 1433590_at |
Herc3 |
hect domain and RLD 3 |
6 |
58831464, 58833699, 58831464 |
BM239854 |
73998 |
19 |
cytoplasm ubiquitin-dependent protein catabolic process protein ubiquitination ubiquitin protein ligase activity |
04120 |
| 1429443_at |
Cpne4 |
copine IV |
9 |
104566700, 104569654, 104588057 |
AK014396 |
74020 |
22 |
protein binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding plasma membrane metal ion binding cellular response to calcium ion |
|
| 1448407_at |
Vsir |
V-set immunoregulatory receptor |
10 |
60346850 |
BC003967 |
74048 |
56 |
negative regulation of T cell cytokine production protein binding plasma membrane plasma membrane plasma membrane external side of plasma membrane positive regulation of gene expression positive regulation of endopeptidase activity membrane enzyme binding positive regulation of cell migration BMP signaling pathway BMP signaling pathway positive regulation of BMP signaling pathway positive regulation of BMP signaling pathway zymogen activation negative regulation of type II interferon production negative regulation of interleukin-10 production negative regulation of interleukin-17 production negative regulation of tumor necrosis factor production identical protein binding positive regulation of regulatory T cell differentiation negative regulation of alpha-beta T cell activation stem cell differentiation stem cell differentiation regulation of immune response endopeptidase activator activity positive regulation of collagen catabolic process negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of CD8-positive, alpha-beta T cell proliferation positive regulation of stem cell differentiation |
|
| 1424032_at |
Hvcn1 |
hydrogen voltage-gated channel 1 |
5 |
122210286, 122209728, 122210138 |
BC021548 |
74096 |
68 |
monoatomic ion channel activity plasma membrane monoatomic ion transport response to pH response to zinc ion response to zinc ion membrane membrane apical plasma membrane voltage-gated monoatomic cation channel activity voltage-gated proton channel activity voltage-gated proton channel activity voltage-gated proton channel activity positive regulation of superoxide anion generation monoatomic ion transmembrane transport monoatomic ion channel complex identical protein binding identical protein binding regulation of intracellular pH intracellular pH elevation transmembrane transport regulation of acrosome reaction cellular response to zinc ion cellular response to pH proton transmembrane transport proton transmembrane transport proton transmembrane transport regulation of reactive oxygen species biosynthetic process |
|
| 1428141_at |
Gga2 |
golgi associated, gamma adaptin ear containing, ARF binding protein 2 |
7 |
-121986721 |
AK004632 |
74105 |
26 |
protein binding endosome Golgi apparatus trans-Golgi network trans-Golgi network intracellular protein transport Golgi to plasma membrane transport protein transport membrane vesicle-mediated transport clathrin-coated vesicle small GTPase binding small GTPase binding protein localization to cell surface protein localization to cell surface phosphatidylinositol binding Golgi to plasma membrane protein transport ubiquitin binding |
04142 |
| 1447432_s_at |
Zfp263 |
zinc finger protein 263 |
16 |
3744098 |
AI326880 |
74120 |
26 |
negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding nucleus nucleus regulation of DNA-templated transcription regulation of transcription by RNA polymerase II sequence-specific DNA binding negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II metal ion binding sequence-specific double-stranded DNA binding |
|
| 1434949_at |
Armc8 |
armadillo repeat containing 8 |
9 |
-99478390, -99518244 |
BE995635 |
74125 |
26 |
ubiquitin ligase complex molecular_function nucleus nucleoplasm cytoplasm cytosol GID complex proteasome-mediated ubiquitin-dependent protein catabolic process intracellular membrane-bounded organelle |
|
| 1443609_s_at |
Syvn1 |
synovial apoptosis inhibitor 1, synoviolin |
19 |
6047144, 6046575 |
C85322 |
74126 |
87 |
ubiquitin ligase complex Hrd1p ubiquitin ligase ERAD-L complex in utero embryonic development immature B cell differentiation protein binding nucleoplasm cytoplasm endoplasmic reticulum smooth endoplasmic reticulum ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process response to unfolded protein multicellular organism development endomembrane system membrane protein ubiquitination transferase activity protein catabolic process retrograde protein transport, ER to cytosol ERAD pathway ERAD pathway ERAD pathway Derlin-1 retrotranslocation complex endoplasmic reticulum quality control compartment endoplasmic reticulum quality control compartment endoplasmic reticulum quality control compartment metal ion binding protein stabilization protein stabilization unfolded protein binding protein-folding chaperone binding ATPase binding ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin protein ligase activity intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress protein K48-linked ubiquitination negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway ubiquitin-specific protease binding |
04120 04141 |
| 1428248_at |
Nfx1 |
nuclear transcription factor, X-box binding 1 |
4 |
40970942, 40970905 |
AK005038 |
74164 |
34 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific nucleic acid binding DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleolus cytosol plasma membrane zinc ion binding transferase activity negative regulation of MHC class II biosynthetic process metal ion binding protein autoubiquitination ubiquitin protein ligase activity |
|
| 1428700_at |
P2ry13 |
purinergic receptor P2Y, G-protein coupled 13 |
3 |
-59207893 |
AK008013 |
74191 |
44 |
G protein-coupled receptor activity endoplasmic reticulum plasma membrane signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway negative regulation of adenylate cyclase activity membrane G protein-coupled purinergic nucleotide receptor activity G protein-coupled purinergic nucleotide receptor activity cellular response to organic cyclic compound |
04080 |
| 1436421_s_at |
Arpc5l |
actin related protein 2/3 complex, subunit 5-like |
2 |
39008138 |
BB403233 |
74192 |
25 |
actin binding cytoplasm cytoplasm cytoskeleton Arp2/3 protein complex Arp2/3 protein complex actin cytoskeleton cell migration regulation of actin filament polymerization Arp2/3 complex-mediated actin nucleation Arp2/3 complex-mediated actin nucleation synapse synapse actin filament binding glutamatergic synapse glutamatergic synapse |
04666 04810 05100 |
| 1455700_at |
Mterf2 |
mitochondrial transcription termination factor 2 |
10 |
-85119432, -85119440 |
BB359043 |
74238 |
16 |
nucleic acid binding DNA binding double-stranded DNA binding mitochondrion mitochondrion mitochondrial matrix regulation of DNA-templated transcription termination of mitochondrial transcription mitochondrial nucleoid |
|
| 1429201_at |
Cyld |
CYLD lysine 63 deubiquitinase |
8 |
88697027 |
AK013508 |
74256 |
137 |
immune system process cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity protein binding cytoplasm centrosome spindle cytosol cytosol cytoskeleton microtubule cytoplasmic microtubule plasma membrane proteolysis regulation of mitotic cell cycle regulation of mitotic cell cycle peptidase activity cysteine-type peptidase activity zinc ion binding cytoplasmic side of plasma membrane regulation of tumor necrosis factor-mediated signaling pathway regulation of tumor necrosis factor-mediated signaling pathway membrane Wnt signaling pathway protein deubiquitination protein deubiquitination protein deubiquitination hydrolase activity protein kinase binding midbody negative regulation of NF-kappaB transcription factor activity negative regulation of NF-kappaB transcription factor activity ciliary basal body cell projection CD4-positive or CD8-positive, alpha-beta T cell lineage commitment regulation of protein binding innate immune response regulation of B cell differentiation positive regulation of T cell differentiation negative regulation of JNK cascade negative regulation of JNK cascade metal ion binding homeostasis of number of cells regulation of inflammatory response negative regulation of inflammatory response regulation of T cell receptor signaling pathway positive regulation of T cell receptor signaling pathway regulation of necroptotic process regulation of necroptotic process K63-linked deubiquitinase activity K63-linked deubiquitinase activity K63-linked deubiquitinase activity Met1-linked polyubiquitin deubiquitinase activity proline-rich region binding necroptotic process necroptotic process necroptotic process regulation of microtubule cytoskeleton organization protein K63-linked deubiquitination protein K63-linked deubiquitination negative regulation of canonical Wnt signaling pathway ciliary tip ripoptosome assembly involved in necroptotic process negative regulation of non-canonical NF-kappaB signal transduction regulation of cilium assembly negative regulation of p38MAPK cascade negative regulation of p38MAPK cascade positive regulation of protein localization protein linear deubiquitination protein linear deubiquitination K48-linked deubiquitinase activity negative regulation of interleukin-18-mediated signaling pathway positive regulation of extrinsic apoptotic signaling pathway positive regulation of extrinsic apoptotic signaling pathway regulation of intrinsic apoptotic signaling pathway regulation of intrinsic apoptotic signaling pathway |
04380 04622 |
| 1451776_s_at |
Hopx |
HOP homeobox |
5 |
-77086985, -77086985 |
BC024546 |
74318 |
162 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II trophectodermal cell differentiation trophectodermal cell differentiation DNA binding protein binding nucleus nucleus nucleus cytoplasm regulation of transcription by RNA polymerase II multicellular organism development heart development regulation of heart contraction cell differentiation histone deacetylase regulator activity regulation of protein binding positive regulation of skeletal muscle tissue regeneration negative regulation of cell differentiation lung alveolus development chaperone-mediated protein complex assembly positive regulation of striated muscle cell differentiation positive regulation of gap junction assembly |
|
| 1453485_s_at |
Mettl23 |
methyltransferase like 23 |
11 |
116843514 |
AK016897 |
74319 |
18 |
female pronucleus male pronucleus protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytoplasm chromatin organization multicellular organism development methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity protein-lysine N-methyltransferase activity transferase activity peptidyl-lysine methylation heat shock protein binding methylation protein-containing complex protein-arginine omega-N asymmetric methyltransferase activity histone H3R17 methyltransferase activity histone methyltransferase activity epigenetic programming in the zygotic pronuclei epigenetic programing of male pronucleus positive regulation of transcription by RNA polymerase II cognition DNA-binding transcription factor binding |
|
| 1428663_at |
Sgms2 |
sphingomyelin synthase 2 |
3 |
-131318985, -131318985, -131318985, -131318985, -131318985, -131318985 |
AK017223 |
74442 |
71 |
Golgi membrane Golgi membrane ceramide phosphoethanolamine synthase activity nucleoplasm Golgi apparatus plasma membrane plasma membrane lipid metabolic process sphingolipid metabolic process sphingomyelin biosynthetic process sphingomyelin biosynthetic process sphingomyelin biosynthetic process sphingomyelin biosynthetic process membrane kinase activity phosphorylation transferase activity phosphotransferase activity, for other substituted phosphate groups regulation of bone mineralization sphingomyelin synthase activity sphingomyelin synthase activity sphingomyelin synthase activity sphingomyelin synthase activity ceramide biosynthetic process ceramide biosynthetic process ceramide cholinephosphotransferase activity ceramide cholinephosphotransferase activity ceramide cholinephosphotransferase activity ceramide phosphoethanolamine biosynthetic process |
00600 01100 |
| 1430005_a_at |
Batf2 |
basic leucine zipper transcription factor, ATF-like 2 |
19 |
6164438 |
AK016990 |
74481 |
32 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cell differentiation defense response to protozoan myeloid dendritic cell differentiation RNA polymerase II transcription regulator complex |
|
| 1447522_s_at |
Tnks2 |
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
19 |
36834231 |
AI662480 |
74493 |
33 |
protein polyubiquitination pericentriolar material telomere maintenance chromosome, telomeric region NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity nucleus nucleus nuclear envelope chromosome cytoplasm cytoplasm Golgi apparatus membrane Wnt signaling pathway transferase activity glycosyltransferase activity nucleotidyltransferase activity enzyme binding multicellular organism growth regulation of multicellular organism growth metal ion binding perinuclear region of cytoplasm protein localization to chromosome, telomeric region protein localization to chromosome, telomeric region protein poly-ADP-ribosylation protein auto-ADP-ribosylation positive regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway positive regulation of telomere capping positive regulation of telomere capping negative regulation of telomere maintenance via telomere lengthening NAD+-protein ADP-ribosyltransferase activity |
|
| 1429570_at |
Mlkl |
mixed lineage kinase domain-like |
8 |
-111311797 |
AK018636 |
74568 |
217 |
nucleotide binding protein binding ATP binding ATP binding nucleus cytoplasm cytoplasm cytosol plasma membrane plasma membrane protein phosphorylation cell surface receptor signaling pathway programmed cell death membrane protein kinase binding cell junction identical protein binding protein-containing complex binding defense response to virus defense response to virus protein homotrimerization necroptotic process necroptotic process necroptotic signaling pathway necroptotic signaling pathway execution phase of necroptosis execution phase of necroptosis execution phase of necroptosis |
|
| 1430143_at |
4930426D05Rik |
RIKEN cDNA 4930426D05 gene |
18 |
21651564 |
AK015205 |
74644 |
11 |
molecular_function cellular_component biological_process |
|
| 1433756_at |
S100pbp |
S100P binding protein |
4 |
-129148001, -129148001 |
BI452674 |
74648 |
16 |
molecular_function nucleus nucleus cytosol cytosol biological_process nuclear speck calcium-dependent protein binding calcium-dependent protein binding |
|
| 1429319_at |
Rhoh |
ras homolog family member H |
5 |
65861219, 65863583 |
BM243660 |
74734 |
35 |
nucleotide binding immunological synapse GTPase activity GTPase activity protein binding GTP binding GTP binding cytoplasm cytoplasm plasma membrane plasma membrane actin filament organization signal transduction small GTPase-mediated signal transduction membrane kinase inhibitor activity protein kinase binding T cell differentiation negative regulation of canonical NF-kappaB signal transduction mast cell activation positive regulation of T cell differentiation |
04670 |
| 1425294_at |
Slamf8 |
SLAM family member 8 |
1 |
-172581376 |
BC024587 |
74748 |
18 |
leukocyte chemotaxis involved in inflammatory response leukocyte chemotaxis involved in inflammatory response B-1 B cell lineage commitment negative regulation of macrophage chemotaxis membrane regulation of NAD(P)H oxidase activity signaling receptor activity signaling receptor activity defense response to bacterium identical protein binding regulation of kinase activity regulation of B cell differentiation regulation of B cell differentiation negative regulation of respiratory burst involved in inflammatory response cellular response to xenobiotic stimulus negative regulation of monocyte chemotaxis phagosome acidification negative regulation of neutrophil migration negative regulation of dendritic cell chemotaxis |
|
| 1435465_at |
Kbtbd11 |
kelch repeat and BTB (POZ) domain containing 11 |
8 |
15011024 |
AW049906 |
74901 |
22 |
molecular_function cellular_component biological_process |
|
| 1455169_at |
Rab11fip2 |
RAB11 family interacting protein 2 (class I) |
19 |
-59902883, -59902883 |
BG076094 |
74998 |
25 |
phagocytic cup phagocytic cup nucleoplasm endosome endosome plasma membrane phagocytosis protein transport membrane protein kinase binding establishment of cell polarity small GTPase binding TRAM-dependent toll-like receptor 4 signaling pathway insulin secretion involved in cellular response to glucose stimulus identical protein binding protein homodimerization activity intracellular membrane-bounded organelle positive regulation of GTPase activity regulated exocytosis regulated exocytosis positive regulation of protein localization to plasma membrane |
04144 |
| 1433514_at |
Etnk1 |
ethanolamine kinase 1 |
6 |
143167229 |
BG066916 |
75320 |
35 |
nucleotide binding ethanolamine kinase activity ethanolamine kinase activity ATP binding cytoplasm cytoplasm lipid metabolic process phosphatidylethanolamine biosynthetic process phosphatidylethanolamine biosynthetic process phospholipid biosynthetic process kinase activity phosphorylation transferase activity |
00564 01100 |
| 1453266_at |
Zbtb4 |
zinc finger and BTB domain containing 4 |
11 |
69765911 |
BB767069 |
75580 |
25 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding nucleus nucleoplasm chromosome cytosol regulation of DNA-templated transcription DNA damage response methyl-CpG binding methyl-CpNpG binding nuclear body protein kinase binding protein homodimerization activity sequence-specific DNA binding negative regulation of DNA-templated transcription metal ion binding |
|
| 1424713_at |
Calml4 |
calmodulin-like 4 |
9 |
62858103 |
AY061807 |
75600 |
20 |
calcium ion binding calcium ion binding microvillus enzyme regulator activity myosin head/neck binding brush border assembly |
|
| 1449303_at |
Sesn3 |
sestrin 3 |
9 |
14276300 |
NM_030261 |
75747 |
34 |
protein binding nucleus cytoplasm positive regulation of macroautophagy oxidoreductase activity oxidoreductase activity, acting on peroxide as acceptor TORC2 complex response to insulin response to insulin cellular response to amino acid starvation TORC2 signaling cellular response to glucose starvation glucose homeostasis glucose homeostasis regulation of insulin receptor signaling pathway regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GATOR2 complex leucine binding cellular response to amino acid stimulus cellular response to leucine regulation of response to reactive oxygen species negative regulation of TORC1 signaling negative regulation of TORC1 signaling negative regulation of TORC1 signaling cellular response to leucine starvation |
04115 |
| 1428651_at |
Klhl24 |
kelch-like 24 |
16 |
20097553 |
AK004187 |
75785 |
20 |
cytoplasm adherens junction protein ubiquitination desmosome Cul3-RING ubiquitin ligase complex cell projection intermediate filament organization protein autoubiquitination anchoring junction regulation of kainate selective glutamate receptor activity |
|
| 1435374_at |
Cdyl2 |
chromodomain protein, Y chromosome-like 2 |
8 |
-116568723 |
BG071670 |
75796 |
20 |
transcription corepressor activity nucleus nucleus methylated histone binding |
|
| 1427428_at |
Clec4g |
C-type lectin domain family 4, member g |
8 |
-3716070 |
BC025069 |
75863 |
24 |
virus receptor activity T cell mediated immunity negative regulation of T cell mediated immunity negative regulation of T cell mediated immunity protein binding mannose binding plasma membrane plasma membrane immune response external side of plasma membrane membrane carbohydrate binding carbohydrate binding polysaccharide binding immature T cell proliferation in thymus negative regulation of immature T cell proliferation in thymus negative regulation of T cell proliferation biological process involved in interspecies interaction between organisms alpha-beta T cell proliferation negative regulation of alpha-beta T cell proliferation symbiont entry into host cell fructose binding carbohydrate derivative binding virus coreceptor activity positive regulation of viral life cycle |
|
| 1427902_at |
Srrm2 |
serine/arginine repetitive matrix 2 |
17 |
23803224, 23803186 |
BQ176063 |
75956 |
36 |
mRNA splicing, via spliceosome mRNA binding nucleus spliceosomal complex mRNA processing RNA splicing Cajal body nuclear speck C2H2 zinc finger domain binding U2-type precatalytic spliceosome U2-type catalytic step 2 spliceosome catalytic step 2 spliceosome |
|
| 1428694_at |
Mir17hg |
Mir17 host gene (non-protein coding) |
14 |
115044389 |
AK017164 |
75957 |
35 |
molecular_function cellular_component response to wounding |
|
| 1434236_at |
Zdhhc20 |
zinc finger, DHHC domain containing 20 |
14 |
-57832701 |
BB667600 |
75965 |
21 |
Golgi membrane cytoplasm endoplasmic reticulum endoplasmic reticulum Golgi apparatus Golgi apparatus plasma membrane protein targeting to membrane zinc ion binding membrane synaptic vesicle maturation palmitoyltransferase activity transferase activity acyltransferase activity peptidyl-L-cysteine S-palmitoylation peptidyl-L-cysteine S-palmitoylation protein palmitoylation protein-cysteine S-palmitoyltransferase activity protein-cysteine S-palmitoyltransferase activity intracellular membrane-bounded organelle positive regulation by host of viral process metal ion binding |
|
| 1452970_at |
Zmym2 |
zinc finger, MYM-type 2 |
14 |
56886602, 56886602, 56886842 |
AK017929 |
76007 |
42 |
protein binding nucleus zinc ion binding PML body ubiquitin conjugating enzyme binding negative regulation of DNA-templated transcription metal ion binding |
|
| 1429672_at |
5830407E08Rik |
RIKEN cDNA 5830407E08 gene |
2 |
|
BB234837 |
76013 |
7 |
molecular_function cellular_component biological_process |
|
| 1436491_at |
Gm11346 |
X-linked lymphocyte-regulated 5 pseudogene |
13 |
-24598124 |
BB387637 |
76024 |
8 |
|
|
| 1441317_x_at |
Jakmip1 |
janus kinase and microtubule interacting protein 1 |
5 |
37050856, 37085235 |
BB316060 |
76071 |
21 |
RNA binding cytoplasm cytoskeleton microtubule microtubule binding protein transport microtubule cytoskeleton membrane kinesin binding kinase binding GABA receptor binding GABA receptor binding cognition ribonucleoprotein complex |
|
| 1428457_at |
Ttpal |
tocopherol (alpha) transfer protein-like |
2 |
163602313, 163607211 |
AK014262 |
76080 |
15 |
molecular_function biological_process phosphatidylinositol bisphosphate binding |
|
| 1435959_at |
Arhgap15 |
Rho GTPase activating protein 15 |
2 |
43787354, 43748823, 43748823 |
BM246535 |
76117 |
24 |
GTPase activator activity nucleoplasm cytoplasm cytoplasm plasma membrane signal transduction regulation of cell shape membrane regulation of GTPase activity |
|
| 1428696_at |
Rftn1 |
raftlin lipid raft linker 1 |
17 |
-49993306 |
AK009372 |
76438 |
20 |
membrane raft assembly T cell antigen processing and presentation double-stranded RNA binding cytoplasm endosome plasma membrane membrane protein transport into membrane raft positive regulation of interleukin-17 production protein-containing complex dsRNA transport toll-like receptor 3 signaling pathway positive regulation of growth rate response to exogenous dsRNA membrane raft T cell receptor signaling pathway B cell receptor signaling pathway protein localization to membrane raft |
|
| 1456542_s_at |
Qrsl1 |
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 |
10 |
-43874189 |
BB517855 |
76563 |
19 |
nucleotide binding catalytic activity ATP binding mitochondrion mitochondrion mitochondrion translation ligase activity glutamyl-tRNA(Gln) amidotransferase complex glutamyl-tRNA(Gln) amidotransferase complex regulation of protein stability mitochondrial translation mitochondrial translation mitochondrial translation glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity glutaminyl-tRNAGln biosynthesis via transamidation glutaminyl-tRNAGln biosynthesis via transamidation |
|
| 1453568_at |
Dapl1 |
death associated protein-like 1 |
2 |
59484652 |
BE633038 |
76747 |
20 |
cellular_component apoptotic process negative regulation of autophagy cell differentiation cellular response to amino acid starvation death domain binding apoptotic signaling pathway negative regulation of CD8-positive, alpha-beta T cell activation |
|
| 1435274_at |
Spopl |
speckle-type BTB/POZ protein-like |
2 |
-23510053 |
BQ175341 |
76857 |
26 |
nucleus nucleus cytoplasm regulation of proteolysis negative regulation of protein ubiquitination Cul3-RING ubiquitin ligase complex ubiquitin protein ligase binding proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process |
|
| 1417290_at |
Lrg1 |
leucine-rich alpha-2-glycoprotein 1 |
17 |
-56119677 |
NM_029796 |
76905 |
52 |
positive regulation of endothelial cell proliferation positive regulation of endothelial cell proliferation type II transforming growth factor beta receptor binding transforming growth factor beta receptor binding voltage-gated potassium channel activity extracellular space extracellular space voltage-gated potassium channel complex response to bacterium positive regulation of epithelial to mesenchymal transition positive regulation of keratinocyte proliferation positive regulation of keratinocyte proliferation positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of transforming growth factor beta receptor signaling pathway type I transforming growth factor beta receptor binding wound healing, spreading of epidermal cells wound healing, spreading of epidermal cells intracellular membrane-bounded organelle transmembrane transporter binding positive regulation of angiogenesis positive regulation of angiogenesis positive regulation of angiogenesis positive regulation of angiogenesis brown fat cell differentiation keratinocyte migration keratinocyte migration positive regulation of epithelial cell proliferation involved in wound healing positive regulation of epithelial cell proliferation involved in wound healing leukocyte adhesion to vascular endothelial cell leukocyte adhesion to vascular endothelial cell potassium channel activator activity |
|
| 1428207_at |
Bcl7a |
B cell CLL/lymphoma 7A |
5 |
123344447 |
AK014498 |
77045 |
35 |
chromatin molecular_function chromatin remodeling regulation of transcription by RNA polymerase II positive regulation of cell population proliferation SWI/SNF complex SWI/SNF complex SWI/SNF complex regulation of mitotic metaphase/anaphase transition negative regulation of cell differentiation regulation of G0 to G1 transition GBAF complex positive regulation of stem cell population maintenance regulation of G1/S transition of mitotic cell cycle positive regulation of double-strand break repair regulation of nucleotide-excision repair |
|
| 1428531_at |
Ints7 |
integrator complex subunit 7 |
1 |
191575635 |
BB457797 |
77065 |
26 |
DNA damage checkpoint signaling molecular_function nucleus chromosome cytoplasm DNA damage response snRNA processing nuclear body integrator complex integrator complex snRNA 3'-end processing cellular response to ionizing radiation |
|
| 1426978_at |
Klhl2 |
kelch-like 2, Mayven |
8 |
-64739674 |
AW682368 |
77113 |
23 |
stress fiber actin binding cytoplasm cytoskeleton actin cytoskeleton protein ubiquitination Cul3-RING ubiquitin ligase complex identical protein binding protein homodimerization activity cell projection ubiquitin ligase-substrate adaptor activity |
|
| 1454967_at |
Crebrf |
CREB3 regulatory factor |
17 |
26715649 |
BM246522 |
77128 |
26 |
negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity nucleus nucleus nucleoplasm cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II response to unfolded protein nuclear body nuclear body response to endoplasmic reticulum stress maternal behavior maternal behavior positive regulation of protein catabolic process positive regulation of transcription by RNA polymerase II negative regulation of endoplasmic reticulum unfolded protein response negative regulation of glucocorticoid mediated signaling pathway negative regulation of glucocorticoid mediated signaling pathway positive regulation of prolactin signaling pathway |
|
| 1428407_at |
Hnrnpa0 |
heterogeneous nuclear ribonucleoprotein A0 |
13 |
-58125878 |
BG073366 |
77134 |
28 |
nucleic acid binding RNA binding mRNA binding nucleus nucleus nucleoplasm inflammatory response protein kinase binding response to lipopolysaccharide mRNA 3'-UTR AU-rich region binding mRNA 3'-UTR AU-rich region binding synapse synapse 3'-UTR-mediated mRNA stabilization 3'-UTR-mediated mRNA stabilization ribonucleoprotein complex |
|
| 1434084_at |
Zfp266 |
zinc finger protein 266 |
9 |
-20495068 |
BF142017 |
77519 |
22 |
RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II |
|
| 1451574_at |
Bcl9 |
B cell CLL/lymphoma 9 |
3 |
-97203661 |
BC019641 |
77578 |
45 |
transcription coactivator activity nucleus cytoplasm Golgi apparatus Golgi apparatus cis-Golgi network cis-Golgi network transcription by RNA polymerase II beta-catenin binding beta-catenin binding myotube differentiation involved in skeletal muscle regeneration Wnt signaling pathway sarcoplasm somatic stem cell population maintenance skeletal muscle cell differentiation myoblast differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II canonical Wnt signaling pathway canonical Wnt signaling pathway beta-catenin-TCF complex beta-catenin-TCF complex |
|
| 1427532_at |
Trat1 |
T cell receptor associated transmembrane adaptor 1 |
16 |
-48730773 |
BB622792 |
77647 |
15 |
negative regulation of receptor recycling negative regulation of receptor recycling adaptive immune response immune system process molecular_function plasma membrane membrane centriolar satellite T cell receptor complex T cell receptor complex positive regulation of calcium-mediated signaling positive regulation of T cell receptor signaling pathway positive regulation of T cell receptor signaling pathway negative regulation of transport mitotic spindle |
|
| 1434105_at |
Epm2aip1 |
EPM2A interacting protein 1 |
9 |
111271844 |
AV340515 |
77781 |
23 |
protein binding nucleus cytoplasm endoplasmic reticulum glycogen biosynthetic process response to insulin identical protein binding positive regulation of glycogen biosynthetic process positive regulation of glycogen biosynthetic process cytoplasmic side of endoplasmic reticulum membrane positive regulation of glycogen (starch) synthase activity |
|
| 1429088_at |
Lbh |
limb-bud and heart |
17 |
72918304 |
AK007400 |
77889 |
32 |
nucleus nucleus nucleus cytoplasm regulation of DNA-templated transcription multicellular organism development regulation of gene expression mammary gland development protein-containing complex negative regulation of intracellular estrogen receptor signaling pathway regulation of MAPK cascade negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription mammary gland epithelial cell differentiation positive regulation of somatic stem cell population maintenance positive regulation of somatic stem cell division positive regulation of mammary stem cell proliferation negative regulation of stem cell differentiation |
|
| 1421144_at |
Rpgrip1 |
retinitis pigmentosa GTPase regulator interacting protein 1 |
14 |
52110902 |
NM_023879 |
77945 |
48 |
protein binding cilium axoneme visual perception thromboxane A2 receptor binding photoreceptor connecting cilium photoreceptor connecting cilium eye photoreceptor cell development cell projection neuron projection retinal rod cell development response to stimulus retina development in camera-type eye neural precursor cell proliferation non-motile cilium photoreceptor distal connecting cilium non-motile cilium assembly |
|
| 1438018_at |
Hook1 |
hook microtubule tethering protein 1 |
4 |
95967378 |
BB463518 |
77963 |
34 |
actin binding protein binding cytoplasm cytoplasm centrosome cytoskeleton microtubule Golgi organization endosome organization lysosome organization multicellular organism development spermatogenesis spermatid development microtubule binding microtubule binding microtubule binding endosome to lysosome transport protein transport microtubule cytoskeleton cell differentiation cytoskeleton-dependent intracellular transport cytoskeleton-dependent intracellular transport HOPS complex cytoplasmic microtubule organization cytoplasmic microtubule organization identical protein binding protein homodimerization activity early endosome to late endosome transport dynein light intermediate chain binding FHF complex manchette assembly protein localization to perinuclear region of cytoplasm |
|
| 1424256_at |
Rdh12 |
retinol dehydrogenase 12 |
12 |
79208912 |
BC016204 |
77974 |
29 |
photoreceptor inner segment NAD-retinol dehydrogenase activity NAD-retinol dehydrogenase activity lipid metabolic process visual perception visual perception oxidoreductase activity retinol metabolic process retinol metabolic process response to stimulus NADP-retinol dehydrogenase activity cellular detoxification of aldehyde cellular detoxification of aldehyde |
00830 01100 |
| 1428789_at |
Ralgps2 |
Ral GEF with PH domain and SH3 binding motif 2 |
1 |
-156804165, -156804165 |
AK008856 |
78255 |
30 |
guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity cytoplasm plasma membrane plasma membrane small GTPase-mediated signal transduction Ras protein signal transduction membrane positive regulation of GTPase activity |
|
| 1428004_at |
Snrnp25 |
small nuclear ribonucleoprotein 25 (U11/U12) |
11 |
32205414 |
BC028766 |
78372 |
17 |
mRNA splicing, via spliceosome molecular_function nucleus nucleoplasm spliceosomal complex U12-type spliceosomal complex U12-type spliceosomal complex cytosol mRNA processing biological_process RNA splicing intercellular bridge |
|
| 1422952_at |
Sapcd1 |
suppressor APC domain containing 1 |
17 |
-35025972 |
NM_023893 |
78376 |
16 |
molecular_function cellular_component biological_process |
|
| 1448618_at |
Mvp |
major vault protein |
7 |
-126986859 |
NM_080638 |
78388 |
40 |
nucleus nucleus cytoplasm cytoplasm cytosol cytoskeleton cell population proliferation protein kinase binding protein phosphatase binding negative regulation of protein autophosphorylation ERBB signaling pathway negative regulation of epidermal growth factor receptor signaling pathway identical protein binding perinuclear region of cytoplasm negative regulation of protein tyrosine kinase activity protein activation cascade ribonucleoprotein complex |
|
| 1427469_at |
Helz |
helicase with zinc finger domain |
11 |
107547932 |
BI251153 |
78455 |
28 |
nucleotide binding RNA binding helicase activity protein binding ATP binding nucleus cytosol hydrolase activity regulatory ncRNA-mediated post-transcriptional gene silencing P granule metal ion binding |
|
| 1437249_at |
Skap1 |
src family associated phosphoprotein 1 |
11 |
96464590 |
BG075562 |
78473 |
28 |
immunological synapse positive regulation of cell-matrix adhesion adaptive immune response immune system process positive regulation of adaptive immune response protein binding nucleus nucleoplasm cytoplasm cytoplasm cytosol cytosol plasma membrane plasma membrane plasma membrane cell-cell junction membrane protein kinase binding protein phosphatase binding protein-containing complex positive regulation of integrin activation positive regulation of cell-cell adhesion mediated by integrin positive regulation of heterotypic cell-cell adhesion T cell receptor complex SH2 domain binding plasma membrane raft protein-containing complex binding positive regulation of cell adhesion positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II T cell receptor signaling pathway protein localization to plasma membrane positive regulation of leukocyte cell-cell adhesion |
|
| 1435698_at |
Rictor |
RPTOR independent companion of MTOR, complex 2 |
15 |
6708380 |
BQ176694 |
78757 |
280 |
regulation of protein phosphorylation positive regulation of endothelial cell proliferation protein binding cytoskeleton organization multicellular organism development embryo development ending in birth or egg hatching regulation of gene expression peptidyl-serine phosphorylation protein kinase binding actin cytoskeleton organization positive regulation of cell growth positive regulation of actin filament polymerization cellular response to nutrient levels TOR signaling TORC2 complex TORC2 complex TORC2 complex positive regulation of TOR signaling regulation of actin cytoskeleton organization regulation of peptidyl-serine phosphorylation TORC2 signaling TORC2 signaling regulation of phosphorylation ribosome binding negative regulation of apoptotic process regulation of GTPase activity protein serine/threonine kinase activator activity protein serine/threonine kinase activator activity regulation of inflammatory response positive regulation of peptidyl-tyrosine phosphorylation regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction molecular adaptor activity regulation of establishment of cell polarity |
04150 |
| 1429612_at |
Eml4 |
echinoderm microtubule associated protein like 4 |
17 |
83350930, 83350940 |
AK019611 |
78798 |
26 |
microtubule cytoskeleton organization cytoplasm microtubule organizing center cytosol cytoskeleton microtubule negative regulation of microtubule depolymerization cell cycle mitotic metaphase chromosome alignment microtubule binding attachment of spindle microtubules to kinetochore microtubule cytoskeleton microtubule cytoskeleton midbody alpha-tubulin binding protein self-association beta-tubulin binding cell division mitotic spindle mitotic spindle |
|
| 1452815_at |
P2ry10 |
purinergic receptor P2Y, G-protein coupled 10 |
X |
107088491, 107089332 |
AK020001 |
78826 |
15 |
G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane positive regulation of Rho protein signal transduction |
04080 |
| 1434758_at |
Crispld2 |
cysteine-rich secretory protein LCCL domain containing 2 |
8 |
119992437 |
BB745401 |
78892 |
25 |
glycosaminoglycan binding glycosaminoglycan binding extracellular region extracellular space heparin binding transport vesicle extracellular matrix organization extracellular matrix face morphogenesis |
|
| 1448376_at |
Wrnip1 |
Werner helicase interacting protein 1 |
13 |
32802029 |
NM_030215 |
78903 |
28 |
nucleotide binding DNA synthesis involved in DNA repair DNA synthesis involved in DNA repair chromosome, telomeric region immune system process DNA binding protein binding ATP binding nucleus nucleus nucleus cytoplasm DNA replication DNA-templated DNA replication DNA repair DNA damage response enzyme activator activity hydrolase activity ATP hydrolysis activity single-stranded DNA helicase activity regulation of DNA-templated DNA replication initiation identical protein binding innate immune response metal ion binding perinuclear region of cytoplasm |
|
| 1416897_at |
Parp9 |
poly (ADP-ribose) polymerase family, member 9 |
16 |
35938469 |
NM_030253 |
80285 |
24 |
DNA damage checkpoint signaling negative regulation of transcription by RNA polymerase II positive regulation of defense response to virus by host immune system process transcription corepressor activity transcription corepressor activity NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity enzyme inhibitor activity nucleus nucleus nucleoplasm cytoplasm cytoplasm mitochondrion cytosol DNA repair double-strand break repair DNA damage response post-transcriptional regulation of gene expression negative regulation of gene expression negative regulation of gene expression transferase activity glycosyltransferase activity nucleotidyltransferase activity enzyme binding protein-containing complex positive regulation of chromatin binding histone binding positive regulation of tyrosine phosphorylation of STAT protein negative regulation of catalytic activity ubiquitin-like protein ligase binding ubiquitin-like protein ligase binding innate immune response positive regulation of DNA-templated transcription defense response to virus regulation of response to type II interferon positive regulation of type II interferon-mediated signaling pathway positive regulation of type II interferon-mediated signaling pathway positive regulation of type II interferon-mediated signaling pathway protein poly-ADP-ribosylation ADP-D-ribose binding site of DNA damage STAT family protein binding NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity positive regulation of protein localization to nucleus NAD+-protein ADP-ribosyltransferase activity |
|
| 1439610_at |
Rab27b |
RAB27B, member RAS oncogene family |
18 |
-69979130, -69979130 |
BE980253 |
80718 |
68 |
nucleotide binding GTPase activity GTPase activity G protein activity protein binding GTP binding GTP binding GTP binding endosome late endosome Golgi apparatus Golgi apparatus Golgi stack exocytosis membrane apical plasma membrane apical plasma membrane hydrolase activity regulation of exocytosis GDP binding protein domain specific binding trans-Golgi network transport vesicle secretory granule synaptic vesicle membrane myosin V binding multivesicular body membrane melanosome melanosome zymogen granule membrane positive regulation of exocytosis positive regulation of exocytosis synaptic vesicle endocytosis exocytic vesicle multivesicular body sorting pathway anterograde axonal protein transport |
04972 |
| 1421408_at |
Igsf6 |
immunoglobulin superfamily, member 6 |
7 |
-121064066 |
NM_030691 |
80719 |
13 |
molecular_function cellular_component biological_process membrane |
|
| 1446957_s_at |
N4bp1 |
NEDD4 binding protein 1 |
8 |
-86841138 |
C81621 |
80750 |
30 |
negative regulation of cytokine production immune system process RNA binding mRNA binding nuclease activity RNA nuclease activity protein binding nucleus nucleus nucleolus cytoplasm cytosol PML body PML body hydrolase activity negative regulation of protein ubiquitination negative regulation of protein ubiquitination negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of proteasomal ubiquitin-dependent protein catabolic process cellular response to UV cellular response to UV ubiquitin binding negative regulation of viral genome replication innate immune response regulation of innate immune response |
|
| 1417688_at |
Fam20c |
FAM20C, golgi associated secretory pathway kinase |
5 |
138755080 |
NM_030565 |
80752 |
53 |
Golgi membrane nucleotide binding skeletal system development protease binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity calcium ion binding ATP binding extracellular region extracellular space extracellular space extracellular space nucleoplasm cytoplasm endoplasmic reticulum Golgi apparatus Golgi apparatus protein phosphorylation protein phosphorylation protein phosphorylation membrane kinase activity phosphorylation transferase activity manganese ion binding positive regulation of bone mineralization biomineral tissue development osteoclast maturation regulation of fibroblast growth factor receptor signaling pathway protein self-association positive regulation of osteoblast differentiation protein autophosphorylation metal ion binding regulation of phosphorus metabolic process enamel mineralization enamel mineralization odontoblast differentiation dentinogenesis |
|
| 1451426_at |
Dhx58 |
DExH-box helicase 58 |
11 |
-100694883 |
AF316999 |
80861 |
39 |
nucleotide binding immune system process cytoplasmic pattern recognition receptor signaling pathway DNA binding RNA binding RNA helicase activity double-stranded RNA binding double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding helicase activity ATP binding cytoplasm cytoplasm zinc ion binding zinc ion binding response to virus response to bacterium hydrolase activity ATP hydrolysis activity negative regulation of type I interferon production negative regulation of type I interferon production positive regulation of type I interferon production negative regulation of MDA-5 signaling pathway negative regulation of RIG-I signaling pathway negative regulation of RIG-I signaling pathway negative regulation of RIG-I signaling pathway innate immune response regulation of innate immune response negative regulation of innate immune response negative regulation of innate immune response metal ion binding defense response to virus antiviral innate immune response positive regulation of MDA-5 signaling pathway positive regulation of RIG-I signaling pathway |
04622 |
| 1417460_at |
Ifitm2 |
interferon induced transmembrane protein 2 |
7 |
-140954838 |
NM_030694 |
80876 |
34 |
immune system process molecular_function lysosome lysosomal membrane endosome plasma membrane plasma membrane response to virus membrane early endosome membrane late endosome membrane protein-containing complex response to type II interferon response to interferon-alpha response to interferon-beta negative regulation of viral genome replication innate immune response negative regulation of viral entry into host cell negative regulation of viral entry into host cell defense response to virus defense response to virus defense response to virus type I interferon-mediated signaling pathway |
|
| 1449005_at |
Slc16a3 |
solute carrier family 16 (monocarboxylic acid transporters), member 3 |
11 |
120948483, 120949066 |
NM_030696 |
80879 |
79 |
plasma membrane plasma membrane plasma membrane monocarboxylic acid transmembrane transporter activity lactate transmembrane transporter activity symporter activity lactate:proton symporter activity lactate:proton symporter activity monocarboxylic acid transport monocarboxylic acid transport membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane lateral plasma membrane transmembrane transporter activity protein catabolic process nuclear membrane lactate transmembrane transport plasma membrane lactate transport pyruvate catabolic process synapse pyruvate transmembrane transporter activity transmembrane transport parallel fiber to Purkinje cell synapse postsynaptic density membrane pyruvate transmembrane transport |
|
| 1420591_at |
Gpr84 |
G protein-coupled receptor 84 |
15 |
-103308234 |
NM_030720 |
80910 |
33 |
urotensin II receptor activity G protein-coupled receptor activity plasma membrane signal transduction G protein-coupled receptor signaling pathway neuropeptide signaling pathway membrane receptor complex |
|
| 1456054_a_at |
Pum1 |
pumilio RNA-binding family member 1 |
4 |
130663320, 130663356 |
BB314559 |
80912 |
61 |
P-body RNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding mRNA 3'-UTR binding nucleoplasm cytoplasm cytoplasm cytosol cytosol regulation of translation spermatogenesis adult locomotory behavior cytoplasmic stress granule post-transcriptional regulation of gene expression post-transcriptional regulation of gene expression post-transcriptional gene silencing cell differentiation axon miRNA processing miRNA processing miRNA binding regulation of mRNA stability regulation of mRNA stability stem cell differentiation regulation of cell cycle regulation of chromosome segregation mRNA destabilization positive regulation of RIG-I signaling pathway positive regulation of miRNA-mediated gene silencing |
|
| 1421870_at |
Trim44 |
tripartite motif-containing 44 |
2 |
-102300118 |
NM_020267 |
80985 |
22 |
positive regulation of cytokine-mediated signaling pathway positive regulation of defense response to virus by host cytoplasm cytoplasm zinc ion binding regulation of gene expression regulation of gene expression protein ubiquitination positive regulation of DNA-templated transcription metal ion binding protein stabilization protein stabilization ubiquitin protein ligase activity negative regulation of protein K48-linked ubiquitination positive regulation of non-canonical NF-kappaB signal transduction |
|
| 1450350_a_at |
Jdp2 |
Jun dimerization protein 2 |
12 |
85599415, 85600017, 85599104 |
NM_030887 |
81703 |
44 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding chromatin binding double-stranded DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus chromatin remodeling regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cAMP response element binding protein homodimerization activity histone deacetylase binding leucine zipper domain binding protein-containing complex binding fat cell differentiation negative regulation of fat cell differentiation protein heterodimerization activity RNA polymerase II transcription regulator complex histone chaperone activity sequence-specific double-stranded DNA binding |
|
| 1440818_s_at |
Sf3b1 |
splicing factor 3b, subunit 1 |
1 |
-54985169 |
BB161546 |
81898 |
67 |
spliceosomal complex assembly spliceosomal complex assembly mRNA splicing, via spliceosome mRNA splicing, via spliceosome chromatin blastocyst formation chromatin binding RNA binding mRNA binding mRNA binding protein binding nucleus nucleus nucleus spliceosomal complex U2-type spliceosomal complex U2 snRNP U2 snRNP U12-type spliceosomal complex U12-type spliceosomal complex nucleolus chromatin remodeling mRNA processing RNA splicing anterior/posterior pattern specification nuclear matrix nuclear speck small nuclear ribonucleoprotein complex U11/U12 snRNP positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase III U2-type prespliceosome U2-type precatalytic spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome B-WICH complex splicing factor binding |
03040 |
| 1421463_at |
Siglece |
sialic acid binding Ig-like lectin E |
7 |
-43651069 |
AF329269 |
83382 |
55 |
protein binding plasma membrane phagocytosis, engulfment inflammatory response cell adhesion cell adhesion external side of plasma membrane membrane carbohydrate binding sialic acid binding sialic acid binding monosaccharide binding negative regulation of inflammatory response negative regulation of phagocytosis, engulfment negative regulation of phagocytosis, engulfment |
|
| 1449220_at |
Gimap3 |
GTPase, IMAP family member 3 |
6 |
-48764463 |
NM_031247 |
83408 |
20 |
mitochondrial genome maintenance nucleotide binding temperature homeostasis positive regulation of natural killer cell cytokine production positive regulation of humoral immune response mediated by circulating immunoglobulin protein binding GTP binding mitochondrion mitochondrial outer membrane endoplasmic reticulum positive regulation of calcium ion transport into cytosol membrane negative regulation of type II interferon production positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation myeloid dendritic cell differentiation T cell homeostasis negative regulation of apoptotic process negative regulation of nitric oxide biosynthetic process positive regulation of gamma-delta T cell differentiation positive regulation of membrane potential positive regulation of natural killer cell mediated cytotoxicity regulation of mitochondrial membrane permeability negative regulation of T cell activation negative regulation of lipid catabolic process |
|
| 1438069_a_at |
Rbm5 |
RNA binding motif protein 5 |
9 |
-107740494 |
BE446879 |
83486 |
34 |
spliceosomal complex assembly regulation of alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding RNA binding mRNA binding nucleus nucleus nucleoplasm spliceosomal complex mRNA processing apoptotic process RNA splicing positive regulation of apoptotic process metal ion binding |
|
| 1437752_at |
Lin28a |
lin-28 homolog A |
4 |
-134003329 |
BB706377 |
83557 |
153 |
P-body G-quadruplex RNA binding nucleic acid binding RNA binding RNA binding mRNA binding mRNA binding protein binding nucleus nucleus nucleolus nucleolus cytoplasm cytoplasm cytoplasm endoplasmic reticulum rough endoplasmic reticulum cytosol germ cell development germ cell development zinc ion binding cytoplasmic stress granule miRNA metabolic process miRNA catabolic process miRNA catabolic process miRNA catabolic process negative regulation of translation stem cell population maintenance regulatory ncRNA-mediated gene silencing pre-miRNA processing pre-miRNA processing pre-miRNA processing pre-miRNA processing RNA 3'-end processing translation initiation factor binding positive regulation of TOR signaling miRNA binding positive regulation of neuron differentiation negative regulation of glial cell differentiation positive regulation of translation metal ion binding stem cell differentiation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of miRNA-mediated gene silencing pre-miRNA binding RNA 3' uridylation cellular response to glucose stimulus protein-RNA adaptor activity positive regulation of cell proliferation involved in kidney development polysome binding sequence-specific mRNA binding negative regulation of pre-miRNA processing positive regulation of cytoplasmic translation |
|
| 1455940_x_at |
Wdr6 |
WD repeat domain 6 |
9 |
-108572310 |
BB453609 |
83669 |
22 |
tRNA binding wobble position ribose methylation cytoplasm cytoplasm cytosol plasma membrane cell cycle tRNA processing COP9 signalosome negative regulation of cell population proliferation negative regulation of autophagy enzyme regulator activity tRNA methylation protein-containing complex insulin receptor substrate binding G1 to G0 transition |
|
| 1424711_at |
Cemip2 |
cell migration inducing hyaluronidase 2 |
19 |
21778339 |
BC019745 |
83921 |
37 |
angiogenesis hyalurononglucosaminidase activity calcium ion binding nucleolus cytosol plasma membrane multicellular organism development metabolic process membrane hydrolase activity hydrolase activity, acting on glycosyl bonds hyaluronan catabolic process carbohydrate binding intracellular membrane-bounded organelle |
|
| 1419226_at |
Cd96 |
CD96 antigen |
16 |
-46035656 |
NM_032465 |
84544 |
21 |
natural killer cell cytokine production cytokine production involved in inflammatory response negative regulation of natural killer cell cytokine production protein binding cytoplasm inflammatory response cell adhesion cell-matrix adhesion cell-matrix adhesion membrane response to lipopolysaccharide negative regulation of type II interferon production |
|
| 1456426_at |
Clec2i |
C-type lectin domain family 2, member i |
6 |
128887586, 128887589 |
BE686253 |
93675 |
22 |
membrane raft assembly transmembrane signaling receptor activity protein binding endoplasmic reticulum plasma membrane external side of plasma membrane external side of plasma membrane cell surface cell surface membrane carbohydrate binding regulation of actin filament polymerization regulation of interleukin-2 production regulation of T cell proliferation receptor clustering negative regulation of osteoclast differentiation natural killer cell lectin-like receptor binding natural killer cell lectin-like receptor binding natural killer cell lectin-like receptor binding T cell receptor signaling pathway positive regulation of immunological synapse formation |
|
| 1455778_at |
Zkscan8 |
zinc finger with KRAB and SCAN domains 8 |
13 |
-21526419, -21513220 |
AW208912 |
93681 |
22 |
RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific regulation of transcription by RNA polymerase II |
|
| 1426536_at |
Ice2 |
interactor of little elongation complex ELL subunit 2 |
9 |
69397997 |
BE952805 |
93697 |
18 |
euchromatin nucleus nucleoplasm cytosol transcription elongation factor complex Cajal body nuclear body histone locus body snRNA transcription by RNA polymerase II snRNA transcription by RNA polymerase II snRNA transcription by RNA polymerase III snRNA transcription by RNA polymerase III positive regulation of transcription by RNA polymerase III positive regulation of transcription by RNA polymerase III |
|
| 1425295_at |
Rnase2a |
ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin) |
14 |
-51255261 |
BC020070 |
93726 |
12 |
innate immune response in mucosa RNA nuclease activity RNA nuclease activity RNA nuclease activity extracellular space extracellular space chemotaxis defense response to Gram-positive bacterium |
|
| 1418640_at |
Sirt1 |
sirtuin 1 |
10 |
-63319004 |
NM_019812 |
93759 |
1263 |
single strand break repair negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II rDNA heterochromatin formation pyrimidine dimer repair by nucleotide-excision repair pyrimidine dimer repair by nucleotide-excision repair DNA synthesis involved in DNA repair chromatin chromatin euchromatin heterochromatin heterochromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding angiogenesis angiogenesis ovulation from ovarian follicle fibrillar center intracellular glucose homeostasis positive regulation of protein phosphorylation positive regulation of endothelial cell proliferation p53 binding p53 binding p53 binding positive regulation of adaptive immune response transcription coactivator activity transcription corepressor activity transcription corepressor activity transcription corepressor activity histone deacetylase activity protein binding nucleus nucleus nucleus nuclear envelope nuclear inner membrane nuclear inner membrane nucleoplasm nucleoplasm nucleoplasm chromatin silencing complex cytoplasm mitochondrion mitochondrion cytosol chromatin organization chromatin remodeling protein deacetylation protein deacetylation protein deacetylation triglyceride mobilization apoptotic process DNA damage response response to oxidative stress transforming growth factor beta receptor signaling pathway multicellular organism development spermatogenesis regulation of mitotic cell cycle muscle organ development circadian rhythm positive regulation of cell population proliferation intrinsic apoptotic signaling pathway in response to DNA damage cellular response to starvation positive regulation of heart rate negative regulation of gene expression cardiac muscle cell apoptotic process negative regulation of cardiac muscle cell apoptotic process regulation of centrosome duplication negative regulation of triglyceride biosynthetic process positive regulation of cholesterol efflux regulation of lipid storage regulation of glucose metabolic process positive regulation of neuron projection development positive regulation of skeletal muscle cell proliferation positive regulation of macroautophagy positive regulation of macroautophagy protein ubiquitination PML body transferase activity nuclear receptor binding NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity peptidyl-lysine acetylation deacetylase activity deacetylase activity enzyme binding enzyme binding protein domain specific binding cell differentiation macrophage differentiation axon growth cone negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of prostaglandin biosynthetic process heterochromatin formation heterochromatin formation protein destabilization negative regulation of TOR signaling negative regulation of TOR signaling NAD-dependent histone H3K14 deacetylase activity regulation of endodeoxyribonuclease activity negative regulation of NF-kappaB transcription factor activity negative regulation of tumor necrosis factor production response to insulin circadian regulation of gene expression circadian regulation of gene expression protein-containing complex leptin-mediated signaling pathway rDNA heterochromatin rDNA heterochromatin protein lysine deacetylase activity protein lysine deacetylase activity protein lysine deacetylase activity regulation of smooth muscle cell apoptotic process NAD-dependent protein deacetylase activity NAD-dependent protein deacetylase activity NAD-dependent protein deacetylase activity ESC/E(Z) complex intracellular triglyceride homeostasis regulation of peroxisome proliferator activated receptor signaling pathway positive regulation of insulin secretion involved in cellular response to glucose stimulus regulation of cell population proliferation cellular response to glucose starvation vasodilation negative regulation of phosphorylation negative regulation of phosphorylation histone binding response to hydrogen peroxide behavioral response to starvation cholesterol homeostasis intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator identical protein binding regulation of apoptotic process positive regulation of apoptotic process positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of canonical NF-kappaB signal transduction proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process HLH domain binding protein kinase B binding bHLH transcription factor binding negative regulation of DNA-binding transcription factor activity negative regulation of DNA-binding transcription factor activity negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process positive regulation of blood vessel endothelial cell migration response to leptin positive regulation of MHC class II biosynthetic process response to ethanol negative regulation of fat cell differentiation positive regulation of gluconeogenesis positive regulation of gluconeogenesis positive regulation of DNA repair positive regulation of angiogenesis negative regulation of cell cycle negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by glucose positive regulation of insulin receptor signaling pathway metal ion binding NAD-dependent histone H3K9 deacetylase activity NAD-dependent histone H3K9 deacetylase activity NAD-dependent histone H4K16 deacetylase activity rhythmic process white fat cell differentiation mitogen-activated protein kinase binding negative regulation of helicase activity positive regulation of smooth muscle cell differentiation neuron apoptotic process maintenance of nucleus location positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction fatty acid homeostasis negative regulation of growth hormone secretion negative regulation of androgen receptor signaling pathway positive regulation of macrophage cytokine production positive regulation of cell growth involved in cardiac muscle cell development eNoSc complex cellular response to hydrogen peroxide NAD+ binding NAD+ binding lysine-acetylated histone binding regulation of bile acid biosynthetic process UV-damage excision repair cellular response to tumor necrosis factor cellular response to hypoxia cellular response to ionizing radiation regulation of protein serine/threonine kinase activity positive regulation of protein deacetylation regulation of brown fat cell differentiation stress-induced premature senescence energy homeostasis protein depropionylation protein-propionyllysine depropionylase activity DNA-binding transcription factor binding DNA repair-dependent chromatin remodeling histone H4K12 deacetylase activity histone H3K deacetylase activity NAD-dependent histone decrotonylase activity negative regulation of protein localization to nucleus negative regulation of protein acetylation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway negative regulation of attachment of mitotic spindle microtubules to kinetochore negative regulation of reactive oxygen species biosynthetic process positive regulation of adipose tissue development cellular response to resveratrol cellular response to amyloid-beta keratin filament binding cellular response to leukemia inhibitory factor promoter-specific chromatin binding positive regulation of macrophage apoptotic process negative regulation of fibroblast apoptotic process negative regulation of cAMP-dependent protein kinase activity positive regulation of cAMP-dependent protein kinase activity positive regulation of cAMP-dependent protein kinase activity positive regulation of thyroid-stimulating hormone secretion negative regulation of cellular response to testosterone stimulus negative regulation of peptidyl-lysine acetylation negative regulation of cellular senescence positive regulation of cellular senescence positive regulation of double-strand break repair |
|
| 1448709_at |
Arid1a |
AT-rich interaction domain 1A |
4 |
-133679007, -133679007 |
NM_033566 |
93760 |
160 |
negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin chromatin chromatin formation of primary germ layer neural tube closure cardiac chamber development optic cup formation involved in camera-type eye development DNA binding protein binding nucleus nucleoplasm nucleoplasm chromatin organization nucleosome disassembly chromatin remodeling chromatin remodeling chromatin remodeling regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II gastrulation nervous system development embryo implantation SWI/SNF complex SWI/SNF complex SWI/SNF complex SWI/SNF complex nuclear receptor binding stem cell population maintenance regulation of mitotic metaphase/anaphase transition intracellular estrogen receptor signaling pathway androgen receptor signaling pathway forebrain development nucleosome binding nucleosome binding brahma complex glucocorticoid receptor signaling pathway positive regulation of T cell differentiation positive regulation of cell differentiation positive regulation of myoblast differentiation positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription cardiac muscle cell differentiation placenta blood vessel development regulation of G0 to G1 transition SWI/SNF superfamily-type complex npBAF complex npBAF complex nBAF complex nBAF complex nBAF complex bBAF complex ATP-dependent chromatin remodeler activity positive regulation of stem cell population maintenance regulation of G1/S transition of mitotic cell cycle positive regulation of double-strand break repair regulation of nucleotide-excision repair |
|
| 1421968_a_at |
Nipa2 |
non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human) |
7 |
-55931265 |
NM_023647 |
93790 |
21 |
protein binding endosome early endosome plasma membrane plasma membrane monoatomic ion transport magnesium ion transmembrane transporter activity magnesium ion transport magnesium ion transport magnesium ion transport membrane membrane |
|
| 1419006_s_at |
Peli2 |
pellino 2 |
14 |
48120868 |
NM_033602 |
93834 |
25 |
protein polyubiquitination protein polyubiquitination positive regulation of protein phosphorylation protein binding cytosol regulation of Toll signaling pathway membrane transferase activity protein-macromolecule adaptor activity positive regulation of MAPK cascade ubiquitin protein ligase activity ubiquitin protein ligase activity |
|
| 1427322_at |
Brwd1 |
bromodomain and WD repeat domain containing 1 |
16 |
-96066667, -95992091, -96001547 |
BQ031260 |
93871 |
39 |
protein binding nucleus nucleus nucleus nucleoplasm nucleolus cytoplasm cytosol axoneme regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cytoskeleton organization cytoskeleton organization regulation of cell shape regulation of cell shape motile cilium |
|
| 1439352_at |
Trim7 |
tripartite motif-containing 7 |
11 |
48826137, 48837470 |
BB825733 |
94089 |
24 |
nucleus nucleus cytoplasm cytoplasm cytoplasm Golgi apparatus zinc ion binding protein ubiquitination transferase activity metal ion binding defense response to virus ubiquitin protein ligase activity ubiquitin protein ligase activity antiviral innate immune response |
|
| 1455189_at |
Trim33 |
tripartite motif-containing 33 |
3 |
103279292 |
BB400432 |
94093 |
68 |
DNA binding protein binding nucleus nucleus nucleoplasm zinc ion binding gene expression protein ubiquitination transferase activity regulation of transforming growth factor beta receptor signaling pathway negative regulation of BMP signaling pathway metal ion binding ubiquitin protein ligase activity co-SMAD binding R-SMAD binding promoter-specific chromatin binding |
|
| 1417665_a_at |
Cpsf1 |
cleavage and polyadenylation specific factor 1 |
15 |
-76595807 |
NM_053193 |
94230 |
27 |
nucleic acid binding RNA binding nucleus nucleus nucleoplasm mRNA cleavage and polyadenylation specificity factor complex mRNA cleavage and polyadenylation specificity factor complex mRNA polyadenylation mRNA processing enzyme binding mRNA 3'-UTR AU-rich region binding |
03015 |
| 1435768_at |
Arid4b |
AT-rich interaction domain 4B |
13 |
14063783 |
AV371758 |
94246 |
41 |
negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding DNA binding protein binding nucleus nucleus nucleoplasm mitochondrion cytosol DNA methylation chromatin organization regulation of transcription by RNA polymerase II transcription by RNA polymerase II spermatogenesis negative regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway positive regulation of transcription by RNA polymerase II genomic imprinting establishment of Sertoli cell barrier negative regulation of stem cell population maintenance positive regulation of stem cell population maintenance |
|
| 1459900_at |
C79468 |
expressed sequence C79468 |
6 |
|
BQ086025 |
97294 |
1 |
|
|
| 1433475_a_at |
Fam8a1 |
family with sequence similarity 8, member A1 |
13 |
46669476 |
BG075168 |
97863 |
15 |
Hrd1p ubiquitin ligase complex molecular_function biological_process |
|
| 1416234_at |
Lrrc59 |
leucine rich repeat containing 59 |
11 |
94629776 |
AW476171 |
98238 |
24 |
nucleus endoplasmic reticulum membrane mitochondrial nucleoid intracellular membrane-bounded organelle |
|
| 1418998_at |
Kmo |
kynurenine 3-monooxygenase |
1 |
175632192 |
NM_133809 |
98256 |
39 |
monooxygenase activity kynurenine 3-monooxygenase activity kynurenine 3-monooxygenase activity kynurenine 3-monooxygenase activity extracellular space mitochondrion mitochondrial outer membrane mitochondrial outer membrane mitochondrial inner membrane tryptophan catabolic process response to salt stress positive regulation of glutamate secretion membrane NAD(P)H oxidase H2O2-forming activity oxidoreductase activity pyridine nucleotide biosynthetic process NAD metabolic process quinolinate biosynthetic process kynurenic acid biosynthetic process flavin adenine dinucleotide binding kynurenine metabolic process kynurenine metabolic process kynurenine metabolic process FAD binding L-kynurenine metabolic process positive regulation of glutamate secretion, neurotransmission |
00380 01100 |
| 1430165_at |
Stk17b |
serine/threonine kinase 17b (apoptosis-inducing) |
1 |
-53755511 |
AI661948 |
98267 |
36 |
nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleus nucleoplasm plasma membrane protein phosphorylation apoptotic process programmed cell death actin cytoskeleton membrane kinase activity phosphorylation transferase activity intracellular signal transduction intracellular signal transduction positive regulation of apoptotic process Flemming body positive regulation of fibroblast apoptotic process |
|
| 1427208_at |
Zfp451 |
zinc finger protein 451 |
1 |
-33761540, -33801959, -33761544 |
BC024435 |
98403 |
31 |
DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding transcription corepressor activity transcription corepressor activity nucleus nucleus PML body transferase activity protein sumoylation protein sumoylation negative regulation of transforming growth factor beta receptor signaling pathway sequence-specific DNA binding metal ion binding negative regulation of transcription initiation by RNA polymerase II negative regulation of transcription initiation by RNA polymerase II SUMO ligase activity SUMO ligase activity transcription regulator inhibitor activity |
|
| 1436999_at |
Pid1 |
phosphotyrosine interaction domain containing 1 |
1 |
-84036292 |
AI504908 |
98496 |
33 |
negative regulation of protein phosphorylation protein binding cytoplasm cytoplasm cytoplasm mitochondrion organization positive regulation of gene expression regulation of cell population proliferation cellular response to leptin stimulus positive regulation of transcription by RNA polymerase II negative regulation of glucose import negative regulation of glucose import negative regulation of glucose import negative regulation of insulin receptor signaling pathway regulation of mitochondrial membrane potential positive regulation of fat cell proliferation cellular response to cytokine stimulus cellular response to interleukin-6 cellular response to tumor necrosis factor cellular response to fatty acid negative regulation of protein localization to plasma membrane regulation of reactive oxygen species metabolic process regulation of reactive oxygen species metabolic process positive regulation of reactive oxygen species metabolic process negative regulation of ATP biosynthetic process positive regulation of ATP biosynthetic process |
|
| 1419907_s_at |
Fcrla |
Fc receptor-like A |
1 |
-170917593 |
BB219290 |
98752 |
26 |
transmembrane signaling receptor activity protein binding cytoplasm immune response cell surface receptor signaling pathway external side of plasma membrane cell differentiation |
|
| 1426894_s_at |
Eeig1 |
estrogen-induced osteoclastogenesis regulator 1 |
2 |
32535358 |
BC023470 |
98952 |
19 |
molecular_function protein binding cellular_component nucleus cytoplasm biological_process membrane membrane raft positive regulation of osteoclast differentiation |
|
| 1433878_at |
Mrps26 |
mitochondrial ribosomal protein S26 |
2 |
130563756 |
AI648866 |
99045 |
22 |
nucleoplasm mitochondrion mitochondrion mitochondrial inner membrane mitochondrial small ribosomal subunit mitochondrial small ribosomal subunit ribosome mitochondrial translation ribonucleoprotein complex |
|
| 1449628_s_at |
Stard7 |
StAR related lipid transfer domain containing 7 |
2 |
127270228, 127270228, 127270228 |
AI852671 |
99138 |
27 |
myeloid dendritic cell activation cytoplasm mitochondrion inflammatory response lipid binding T-helper 2 cell cytokine production type 2 immune response establishment of skin barrier mucociliary clearance |
|
| 1427946_s_at |
Dpyd |
dihydropyrimidine dehydrogenase |
3 |
118562179 |
BC028831 |
99586 |
23 |
nucleotide binding uracil binding uracil binding iron ion binding cytoplasm cytosol cytosol cytosol purine nucleobase catabolic process pyrimidine nucleobase catabolic process pyrimidine nucleobase catabolic process thymine catabolic process thymine catabolic process uracil catabolic process uracil catabolic process thymidine catabolic process CMP catabolic process dCMP catabolic process response to nutrient circadian rhythm response to xenobiotic stimulus response to organic cyclic compound oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors dihydropyrimidine dehydrogenase (NADP+) activity dihydropyrimidine dehydrogenase (NADP+) activity dihydropyrimidine dehydrogenase (NADP+) activity uracil metabolic process identical protein binding protein homodimerization activity UMP catabolic process dTMP catabolic process dUMP catabolic process metal ion binding NADP binding NADP binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding FAD binding |
00240 00410 00770 00983 01100 |
| 1423555_a_at |
Ifi44 |
interferon-induced protein 44 |
3 |
-151730922 |
BB329808 |
99899 |
19 |
molecular_function cytoplasm immune response response to bacterium |
|