Annotations for selected genes

Probe	Symbol	Description	Chromosome	Chromosome Location	GenBank	Gene	PubMed	Gene Ontology	Pathway
1436530_at	Wfdc17	WAP four-disulfide core domain 17	11	83704055	AA666504	100034251	7	serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity extracellular space antibacterial humoral response innate immune response
1457728_at	Niban3	niban apoptosis regulator 3	8	71597707	BB763642	100037278	11	molecular_function cellular_component biological_process
1446929_at	D130062J21Rik	RIKEN cDNA D130062J21 gene	4		BB459664	100038651	9	molecular_function cellular_component biological_process
1426113_x_at	Trav9d-3	T cell receptor alpha variable 9D-3	14		U07662	100038850	10	molecular_function cellular_component biological_process
1436040_at	Snhg12	small nucleolar RNA host gene 12	4	132308677	BI180630	100039864	26	molecular_function cellular_component biological_process
1456765_at	Nhsl2	NHS like 2	X	101849384	AV339861	100042480	12	molecular_function cellular_component cell differentiation
1428562_at	Mir22hg	Mir22 host gene (non-protein coding)	11	75461538	AK008813	100042498	16	response to wounding
1440451_at	Ankrd66	ankyrin repeat domain 66	17	-43534173	BG085035	100043332	10	molecular_function cellular_component biological_process
1426168_a_at	Trac	T cell receptor alpha constant	14		U95921	100101484	53	plasma membrane response to bacterium signaling receptor activity alpha-beta T cell receptor complex
1426716_at	Tdrd7	tudor domain containing 7	4	45965334, 45972296, 45972830	BC025099	100121	30	lens morphogenesis in camera-type eye lens morphogenesis in camera-type eye lens morphogenesis in camera-type eye RNA binding mRNA binding protein binding cytoplasm multicellular organism development germ cell development spermatogenesis spermatogenesis post-transcriptional regulation of gene expression cell differentiation P granule organization chromatoid body piRNA processing ribonucleoprotein granule P granule P granule lens fiber cell differentiation lens fiber cell differentiation lens fiber cell differentiation ribonucleoprotein complex
1427765_a_at	Trbv14	T cell receptor beta, variable 14	6		M31648	100124678	14	plasma membrane cell surface receptor signaling pathway
1427752_a_at	Trbv29	T cell receptor beta, variable 29	6		U63547	100124698	14	plasma membrane cell surface receptor signaling pathway peptide antigen binding
1433735_a_at	Tmem64	transmembrane protein 64	4	15265819	BG075363	100201	22	protein binding endoplasmic reticulum endoplasmic reticulum membrane osteoclast differentiation regulation of ATP-dependent activity positive regulation of fat cell differentiation negative regulation of osteoblast differentiation positive regulation of osteoclast differentiation positive regulation of osteoclast differentiation positive regulation of bone resorption positive regulation of bone resorption regulation of cytosolic calcium ion concentration regulation of cytosolic calcium ion concentration negative regulation of canonical Wnt signaling pathway
1417300_at	Smpdl3b	sphingomyelin phosphodiesterase, acid-like 3B	4	-132732965	NM_133888	100340	28	immune system process sphingomyelin phosphodiesterase activity protein binding extracellular region extracellular space extracellular space plasma membrane lipid metabolic process sphingomyelin catabolic process inflammatory response phosphoric diester hydrolase activity phosphoric diester hydrolase activity phosphoric diester hydrolase activity phosphoric diester hydrolase activity metabolic process zinc ion binding membrane lipid catabolic process hydrolase activity hydrolase activity, acting on glycosyl bonds negative regulation of toll-like receptor signaling pathway innate immune response negative regulation of innate immune response membrane lipid catabolic process metal ion binding negative regulation of inflammatory response side of membrane
1456393_at	Bbip1	BBSome interacting protein 1	19	-53929658	AI642124	100503572	20	molecular_function cytoplasm BBSome BBSome eating behavior ciliary membrane cilium assembly cilium assembly receptor localization to non-motile cilium receptor localization to non-motile cilium
1440967_at	Gm15708	predicted gene 15708	5	144277060	AI666381	100504231	8	molecular_function cellular_component biological_process
1422892_s_at	H2-Ea	histocompatibility 2, class II antigen E alpha	17	-34341951	U13648	100504404	69	immunological synapse positive regulation of T cell mediated cytotoxicity myeloid dendritic cell antigen processing and presentation antigen processing and presentation of endogenous peptide antigen via MHC class II peptide antigen assembly with MHC class II protein complex peptide antigen assembly with MHC class II protein complex antigen processing and presentation of peptide or polysaccharide antigen via MHC class II lysosome lysosomal membrane lysosomal membrane plasma membrane external side of plasma membrane cell surface immunoglobulin mediated immune response immunoglobulin mediated immune response antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding polysaccharide binding late endosome membrane late endosome membrane positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation peptide antigen binding peptide antigen binding T cell receptor binding MHC class II protein complex MHC class II protein complex positive regulation of memory T cell differentiation regulation of T-helper cell differentiation positive regulation of immune response positive regulation of immune response positive regulation of immune response positive regulation of T cell activation cognition positive regulation of CD4-positive, alpha-beta T cell activation
1420342_at	Gdap10	ganglioside-induced differentiation-associated-protein 10	12	32824115	NM_010268	100504486	5	molecular_function cellular_component response to bacterium
1430622_at	4833423F13Rik	RIKEN cDNA 4833423F13 gene	16		AW764291	100504504	7	molecular_function cellular_component biological_process
1438676_at	Gbp6	guanylate binding protein 6	5	-105270701	BM241485	100702	17	nucleotide binding immune system process GTPase activity GTPase activity GTP binding GTP binding response to bacterium hydrolase activity symbiont-containing vacuole membrane cytoplasmic vesicle cytoplasmic vesicle cellular response to interferon-beta defense response to protozoan defense response to protozoan adhesion of symbiont to host innate immune response defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium cellular response to lipopolysaccharide cellular response to type II interferon cellular response to type II interferon
1416414_at	Emilin1	elastin microfibril interfacer 1	5	30913785	NM_133918	100952	61	aortic valve morphogenesis protein binding extracellular region extracellular region collagen trimer extracellular space extracellular space cell adhesion cell-matrix adhesion regulation of blood pressure positive regulation of gene expression negative regulation of gene expression positive regulation of cell-substrate adhesion cell migration negative regulation of angiogenesis extracellular matrix constituent conferring elasticity extracellular matrix constituent conferring elasticity extracellular matrix constituent conferring elasticity extracellular matrix organization negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of vascular endothelial growth factor receptor signaling pathway extracellular matrix negative regulation of collagen biosynthetic process cell adhesion mediated by integrin integrin alpha4-beta1 complex regulation of cell population proliferation identical protein binding identical protein binding positive regulation of angiogenesis elastic fiber assembly negative regulation of cell activation molecular adaptor activity negative regulation of SMAD protein signal transduction collagen-containing extracellular matrix collagen-containing extracellular matrix collagen-containing extracellular matrix negative regulation of ERK1 and ERK2 cascade integrin binding involved in cell-matrix adhesion positive regulation of defense response to bacterium negative regulation of vascular endothelial growth factor signaling pathway positive regulation of extracellular matrix assembly negative regulation of collagen fibril organization negative regulation of macrophage migration EMILIN complex
1418201_at	Plekhg2	pleckstrin homology domain containing, family G (with RhoGef domain) member 2	7	-28359603	NM_138752	101497	19	guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity regulation of actin filament polymerization regulation of actin filament polymerization small GTPase binding
1434333_a_at	Prkd2	protein kinase D2	7	16843064, 16842901	AW557946	101540	44	nucleotide binding angiogenesis positive regulation of endothelial cell proliferation adaptive immune response immune system process protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity diacylglycerol-dependent serine/threonine kinase activity protein kinase C binding ATP binding nucleus nucleoplasm cytoplasm Golgi apparatus cytosol cytosol plasma membrane protein phosphorylation cell adhesion phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of endothelial cell migration membrane kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation positive regulation of vascular endothelial growth factor receptor signaling pathway positive regulation of interleukin-2 production positive regulation of interleukin-8 production intracellular signal transduction intracellular signal transduction cellular response to vascular endothelial growth factor stimulus positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway positive regulation of blood vessel endothelial cell migration positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of angiogenesis positive regulation of cell adhesion positive regulation of transcription by RNA polymerase II protein autophosphorylation metal ion binding vascular endothelial growth factor receptor signaling pathway T cell receptor signaling pathway positive regulation of T cell receptor signaling pathway positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity regulation of T cell apoptotic process positive regulation of ERK1 and ERK2 cascade protein serine kinase activity positive regulation of intracellular signal transduction positive regulation of DNA biosynthetic process positive regulation of endothelial cell chemotaxis
1423975_s_at	Numa1	nuclear mitotic apparatus protein 1	7	101969842	BC006631	101706	63	establishment of mitotic spindle orientation establishment of mitotic spindle orientation establishment of mitotic spindle orientation spindle pole spindle pole microtubule bundle formation protein binding nucleus nucleoplasm chromosome cytoplasm centrosome centrosome cytosol cytoskeleton microtubule spindle microtubule spindle microtubule plasma membrane cell cortex cell cycle chromosome segregation microtubule binding microtubule binding lipid binding tubulin binding membrane nuclear matrix nuclear matrix protein domain specific binding dendrite positive regulation of BMP signaling pathway astral microtubule organization positive regulation of microtubule polymerization spindle pole centrosome positive regulation of intracellular transport protein-containing complex phosphatidylinositol binding microtubule plus-end microtubule minus-end neuronal cell body protein-containing complex binding apical part of cell positive regulation of keratinocyte differentiation microtubule plus-end binding microtubule minus-end binding cell division positive regulation of hair follicle development positive regulation of chromosome segregation cortical microtubule anastral spindle assembly regulation of mitotic spindle organization lung epithelial cell differentiation mitotic spindle astral microtubule dynein complex binding mitotic spindle regulation of metaphase plate congression microtubule bundle mitotic spindle pole mitotic spindle pole lateral cell cortex disordered domain specific binding cell cortex region cell cortex region positive regulation of protein localization to spindle pole body positive regulation of mitotic spindle elongation positive regulation of protein localization to cell cortex cytoplasmic microtubule bundle positive regulation of chromosome separation positive regulation of spindle assembly mitotic spindle midzone
1460403_at	Psip1	PC4 and SFRS1 interacting protein 1	4	-83461878, -83455680	BF117241	101739	44	mRNA 5'-splice site recognition euchromatin heterochromatin DNA binding chromatin binding transcription coactivator activity nucleus nucleus nucleoplasm chromatin remodeling response to oxidative stress response to heat nuclear periphery positive regulation of transcription by RNA polymerase II supercoiled DNA binding DNA-binding transcription factor binding
1423806_at	Ints4	integrator complex subunit 4	7	97480955	BC013813	101861	24	molecular_function nucleus nucleolus snRNA processing snRNA processing integrator complex integrator complex
1430075_at	Sf3b3	splicing factor 3b, subunit 3	8	-110810491	AK017529	101943	38	SAGA complex mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding protein binding nucleus nucleus nucleoplasm spliceosomal complex U2-type spliceosomal complex U2 snRNP U12-type spliceosomal complex nucleolus regulation of DNA repair mRNA processing RNA splicing U2 snRNA binding negative regulation of protein catabolic process regulation of RNA splicing protein-containing complex binding positive regulation of DNA-templated transcription U2-type precatalytic spliceosome catalytic step 2 spliceosome	03040
1418553_at	Arhgef18	Rho/Rac guanine nucleotide exchange factor 18	8	3393007, 3353436	NM_133962	102098	35	guanyl-nucleotide exchange factor activity cytoplasm cytosol cytoskeleton plasma membrane plasma membrane small GTPase-mediated signal transduction regulation of cell shape membrane actin cytoskeleton organization regulation of Rho protein signal transduction apical part of cell metal ion binding negative regulation of stress fiber assembly protein localization to cell-cell junction
1436501_at	Mtus1	mitochondrial tumor suppressor 1	8	-40990911, -40990911, -40990911, -40990911	BB747681	102103	30	nucleus nucleus nucleolus cytoplasm mitochondrion Golgi apparatus plasma membrane cell cycle microtubule binding regulation of macrophage chemotaxis regulation of macrophage chemotaxis microtubule cytoskeleton membrane
1416065_a_at	Ankrd10	ankyrin repeat domain 10	8	-11613840, -11611580, -11613840	NM_133971	102334	20	molecular_function nucleoplasm
1416210_at	Imp3	IMP3, U3 small nucleolar ribonucleoprotein	9	56937499	NM_133976	102462	21	RNA binding structural constituent of ribosome nucleus nucleoplasm nucleolus rRNA processing rRNA processing small ribosomal subunit rRNA binding snoRNA binding preribosome small-subunit processome small-subunit processome Mpp10 complex Mpp10 complex ribosome biogenesis ribosomal small subunit biogenesis ribosomal small subunit biogenesis ribonucleoprotein complex	03008
1458206_at	Gm30054	predicted gene, 30054	14		BB201845	102631812
1441589_at	Gm38448	predicted gene, 38448	11		BB634277	102632682	7
1430479_at	Gm32819	predicted gene, 32819	9		AK008147	102635498	8
1451190_a_at	Sbk1	SH3-binding kinase 1	7	126272495, 126248396	BC025837	104175	25	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding cellular_component cytoplasm protein phosphorylation kinase activity phosphorylation transferase activity
1428750_at	Cdc42ep2	CDC42 effector protein 2	19	-5917555	BF453885	104252	20	opioid peptide activity GTPase activator activity cytoplasm cytoplasm cytosol cytoskeleton cytoskeleton plasma membrane plasma membrane Rho protein signal transduction regulation of cell shape regulation of cell shape microtubule cytoskeleton membrane actin cytoskeleton organization positive regulation of actin filament polymerization positive regulation of actin filament polymerization small GTPase binding small GTPase binding positive regulation of pseudopodium assembly positive regulation of pseudopodium assembly phagocytic vesicle cellular response to type II interferon
1455643_s_at	Tsr1	TSR1 20S rRNA accumulation	11	74898079	BF228294	104662	25	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GTPase activity GTP binding nucleus preribosome, small subunit precursor U3 snoRNA binding ribosome biogenesis
1437956_at	Pik3r6	phosphoinositide-3-kinase regulatory subunit 5	11	68503018	AV281292	104709	31	angiogenesis protein binding cytoplasm plasma membrane phosphatidylinositol 3-kinase complex phosphatidylinositol 3-kinase complex, class IA phosphatidylinositol 3-kinase complex, class IB G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway membrane regulation of natural killer cell mediated cytotoxicity positive regulation of MAP kinase activity positive regulation of MAP kinase activity positive regulation of T cell differentiation positive regulation of angiogenesis 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity 1-phosphatidylinositol-3-kinase regulator activity 1-phosphatidylinositol-3-kinase regulator activity
1448104_at	Aldh6a1	aldehyde dehydrogenase family 6, subfamily A1	12	-84430720, -84430720	NM_134042	104776	26	methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity nucleoplasm mitochondrion mitochondrion mitochondrion thymine catabolic process thymine catabolic process valine metabolic process valine catabolic process valine catabolic process oxidoreductase activity oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor thiolester hydrolase activity beta-alanine catabolic process thymine metabolic process brown fat cell differentiation	00280 00562 00640 01100
1453864_at	Rdh14	retinol dehydrogenase 14 (all-trans and 9-cis)	12	10390779	AK014097	105014	21	nucleoplasm mitochondrion endoplasmic reticulum cytosol lipid metabolic process alcohol dehydrogenase (NADP+) activity oxidoreductase activity retinol metabolic process NADP-retinol dehydrogenase activity NADP-retinol dehydrogenase activity
1418772_at	Tasor2	transcription activation suppressor family member 2	13	-3566034	NM_134063	105203	19	molecular_function nucleoplasm nucleoplasm cytosol biological_process negative regulation of gene expression, epigenetic
1423746_at	Txndc5	thioredoxin domain containing 5	13	-38500270, -38500270, -38500270	BC016252	105245	52	protein disulfide isomerase activity protein disulfide isomerase activity endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum lumen protein folding protein-disulfide reductase activity oxidoreductase activity isomerase activity	04141
1424824_at	Slain1	SLAIN motif family, member 1	14	103650227	BB704967	105439	17	molecular_function cytoplasm cytoskeleton microtubule nucleation positive regulation of microtubule polymerization cytoplasmic microtubule organization microtubule plus-end
1426459_s_at	Rimoc1	RAB7A interacting MON1-CCZ1 complex subunit 1	15	-3982034	BG073457	106064	14	mitophagy molecular_function nucleoplasm cytoplasm cytosol autophagy
1451199_at	Qtrt2	queuine tRNA-ribosyltransferase accessory subunit 2	16	-43861412	BC017628	106248	18	tRNA binding protein binding cytoplasm mitochondrion mitochondrial outer membrane tRNA modification tRNA processing zinc ion binding tRNA-guanosine(34) queuine transglycosylase activity membrane pentosyltransferase activity protein-containing complex protein-containing complex protein homodimerization activity metal ion binding protein heterodimerization activity tRNA-guanine transglycosylation tRNA-guanine transglycosylation tRNA-guanine transglycosylation transferase complex
1448722_s_at	Ppcs	phosphopantothenoylcysteine synthetase	4	-119418526	NM_026494	106564	19	nucleotide binding heart process phosphopantothenate--cysteine ligase activity phosphopantothenate--cysteine ligase activity ATP binding nucleus cytoplasm acetyl-CoA biosynthetic process coenzyme A biosynthetic process coenzyme A biosynthetic process ligase activity identical protein binding protein homodimerization activity	00770 01100
1416165_at	Rab31	RAB31, member RAS oncogene family	17	-65651725	NM_133685	106572	26	nucleotide binding phagocytic cup GTPase activity GTPase activity protein binding GTP binding cytoplasm endosome early endosome late endosome Golgi apparatus trans-Golgi network intracellular protein transport endomembrane system membrane GDP binding cytoplasmic vesicle receptor internalization trans-Golgi network membrane trans-Golgi network membrane cellular response to insulin stimulus early phagosome membrane Golgi to plasma membrane protein transport Golgi to plasma membrane protein transport regulated exocytosis phagocytic vesicle Golgi vesicle transport positive regulation of phagocytosis, engulfment phagosome maturation	04144
1417971_at	Nrm	nurim (nuclear envelope membrane protein)	17	35861317	NM_134122	106582	20	molecular_function nucleus nuclear envelope nuclear inner membrane nuclear lamina biological_process membrane nuclear membrane nuclear membrane
1428736_at	Gramd2b	GRAM domain containing 2B	18	56432131, 56400339	AV259880	107022	16	molecular_function cytoplasmic microtubule cytoplasmic microtubule biological_process identical protein binding
1427146_at	Carns1	carnosine synthase 1	19	-4164323	BB356222	107239	16	nucleotide binding ATP binding cellular_component ligase activity ATP hydrolysis activity ATP hydrolysis activity ATP hydrolysis activity carnosine biosynthetic process carnosine biosynthetic process carnosine biosynthetic process metal ion binding carnosine synthase activity carnosine synthase activity carnosine synthase activity homocarnosine synthase activity homocarnosine synthase activity homocarnosine synthase activity
1434372_at	AW112010	expressed sequence AW112010	19	-11047611	BE688358	107350	10	molecular_function cellular_component biological_process
1425927_a_at	Atf5	activating transcription factor 5	7	-44812255, -44812255	AF375476	107503	66	transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding chromatin binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex cytoplasm centrosome cytosol cytoskeleton regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II circadian rhythm negative regulation of cell population proliferation post-embryonic development regulation of gene expression tubulin binding kinase binding olfactory bulb interneuron differentiation olfactory bulb interneuron development cerebellar granule cell precursor proliferation olfactory lobe development heat shock protein binding multicellular organism growth negative regulation of apoptotic process negative regulation of apoptotic process sequence-specific DNA binding sequence-specific DNA binding fat cell differentiation fat cell differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of centrosome cycle negative regulation of astrocyte differentiation negative regulation of neurogenesis RNA polymerase II transcription regulator complex negative regulation of cell cycle G2/M phase transition
1424375_s_at	Gimap4	GTPase, IMAP family member 4	6	48684577	BC005577	107526	22	nucleotide binding GTP binding cytoplasm cytosol cytosol intracellular membrane-bounded organelle
1452367_at	Coro2a	coronin, actin binding protein 2A	4	-46536936, -46536936	AI316747	107684	22	actin binding brush border transcription repressor complex actin filament binding
1432492_a_at	Haao	3-hydroxyanthranilate 3,4-dioxygenase	17	-83831353	AK002295	107766	24	3-hydroxyanthranilate 3,4-dioxygenase activity 3-hydroxyanthranilate 3,4-dioxygenase activity 3-hydroxyanthranilate 3,4-dioxygenase activity iron ion binding cytoplasm cytoplasm cytosol ferrous iron binding NAD biosynthetic process response to zinc ion oxidoreductase activity pyridine nucleotide biosynthetic process quinolinate biosynthetic process oxygen binding mitochondrial membrane 'de novo' NAD biosynthetic process from tryptophan response to cadmium ion metal ion binding quinolinate metabolic process quinolinate metabolic process dioxygenase activity neuron cellular homeostasis	00380 01100
1426775_s_at	Scamp1	secretory carrier membrane protein 1	13	-94201309, -94201432	BM115445	107767	26	protein binding endosome Golgi apparatus trans-Golgi network exocytosis endocytosis synaptic vesicle protein transport protein transport membrane protein domain specific binding clathrin-coated vesicle cytoplasmic vesicle membrane synaptic vesicle membrane synaptic vesicle membrane trans-Golgi network membrane zymogen granule membrane synapse establishment of localization in cell recycling endosome membrane recycling endosome membrane
1428669_at	Bmyc	brain expressed myelocytomatosis oncogene	2	25706878	AK012810	107771	31	G1/S transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II MAPK cascade chromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific core promoter sequence-specific DNA binding transcription coregulator binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity nucleus nucleoplasm nucleolus spindle chromatin remodeling DNA methylation-dependent heterochromatin formation regulation of DNA-templated transcription intracellular iron ion homeostasis DNA damage response response to gamma radiation regulation of cell cycle process positive regulation of gene expression regulation of telomere maintenance protein-DNA complex disassembly protein-containing complex identical protein binding positive regulation of cysteine-type endopeptidase activity involved in apoptotic process protein-containing complex binding negative regulation of monocyte differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of fibroblast proliferation negative regulation of fibroblast proliferation positive regulation of epithelial cell proliferation chromosome organization negative regulation of cell division molecular adaptor activity negative regulation of transcription initiation by RNA polymerase II ERK1 and ERK2 cascade E-box binding cellular response to hypoxia cellular response to xenobiotic stimulus Myc-Max complex RNA polymerase II transcription repressor complex DNA-binding transcription factor binding positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator positive regulation of miRNA transcription SCF ubiquitin ligase complex binding
1425706_a_at	Ddb2	damage specific DNA binding protein 2	2	-91211581, -91211580	AY027937	107986	35	protein polyubiquitination DNA binding damaged DNA binding damaged DNA binding ubiquitin-protein transferase activity nucleus nucleus nucleus nucleoplasm chromosome DNA repair DNA repair nucleotide-excision repair pyrimidine dimer repair DNA damage response DNA damage response response to UV response to UV cell junction Cul4A-RING E3 ubiquitin ligase complex Cul4A-RING E3 ubiquitin ligase complex Cul4B-RING E3 ubiquitin ligase complex protein-containing complex cellular response to UV cellular response to UV protein-containing complex binding protein autoubiquitination UV-damage excision repair Cul4-RING E3 ubiquitin ligase complex site of DNA damage	03420 04115 04120
1427860_at	Igkv6-15	immunoglobulin kappa variable 6-15	6		U55641	108022	4	immunoglobulin production extracellular space immune response
1451962_at	Igkv6-20	immunoglobulin kappa variable 6-20	6		L41881	108024	6	immunoglobulin production extracellular space immune response
1419645_at	Cstf2	cleavage stimulation factor, 3' pre-RNA subunit 2	X	134059175, 134059175	BM120662	108062	40	nucleic acid binding RNA binding mRNA binding nucleus nucleoplasm mRNA cleavage and polyadenylation specificity factor complex mRNA cleavage and polyadenylation specificity factor complex mRNA processing nuclear body mRNA 3'-end processing cleavage body	03015
1420994_at	B3gnt5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	16	19760233	BM214359	108105	23	Golgi membrane Golgi apparatus protein glycosylation protein O-linked glycosylation lipid metabolic process multicellular organism development central nervous system development beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity membrane transferase activity glycosyltransferase activity hexosyltransferase activity sphingolipid biosynthetic process lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity	00601 01100
1437506_at	Adamts6	ADAM metallopeptidase with thrombospondin type 1 motif 6	13	104287834	AV286717	108154	19	kidney development cardiac septum development metalloendopeptidase activity proteolysis heart development extracellular matrix organization extracellular matrix aorta development coronary vasculature development
1436780_at	Ogt	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	X	101640217, 101640050	BG065325	108155	161	negative regulation of transcription by RNA polymerase II histone acetyltransferase complex mitophagy positive regulation of transcription from RNA polymerase II promoter by glucose euchromatin negative regulation of protein phosphorylation positive regulation of protein phosphorylation catalytic activity protein binding phosphatidylinositol-3,4,5-trisphosphate binding intracellular anatomical structure nucleus nucleus nucleus nucleus nucleoplasm cytoplasm mitochondrion cytosol plasma membrane glucosamine metabolic process regulation of glycolytic process regulation of gluconeogenesis chromatin organization regulation of transcription by RNA polymerase II protein O-linked glycosylation protein O-linked glycosylation protein O-linked glycosylation protein O-linked glycosylation protein O-linked glycosylation apoptotic process N-acetyltransferase activity lipid binding positive regulation of gene expression negative regulation of peptidyl-threonine phosphorylation membrane protein N-acetylglucosaminyltransferase activity protein processing transferase activity glycosyltransferase activity protein N-acetylglucosaminyltransferase complex protein domain specific binding hemopoiesis negative regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of protein ubiquitination negative regulation of protein ubiquitination chromatin DNA binding negative regulation of proteasomal ubiquitin-dependent protein catabolic process response to insulin circadian regulation of gene expression protein-containing complex negative regulation of peptidyl-serine phosphorylation regulation of Rac protein signal transduction peptide binding zymogen granule identical protein binding cell projection neuronal cell body NSL complex protein-containing complex binding synapse synapse positive regulation of translation positive regulation of cell size positive regulation of proteolysis positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of insulin receptor signaling pathway positive regulation of lipid biosynthetic process intracellular distribution of mitochondria rhythmic process regulation of synapse assembly regulation of synapse assembly regulation of synapse assembly cellular response to lipopolysaccharide cellular response to glucose stimulus negative regulation of protein targeting to membrane protein O-acetylglucosaminyltransferase activity protein O-acetylglucosaminyltransferase activity protein O-acetylglucosaminyltransferase activity protein O-acetylglucosaminyltransferase activity regulation of neurotransmitter receptor localization to postsynaptic specialization membrane regulation of neurotransmitter receptor localization to postsynaptic specialization membrane regulation of neurotransmitter receptor localization to postsynaptic specialization membrane glutamatergic synapse glutamatergic synapse glutamatergic synapse glutamatergic synapse GABA-ergic synapse presynaptic cytosol postsynaptic cytosol positive regulation of cold-induced thermogenesis cerebellar granule cell to Purkinje cell synapse negative regulation of cellular response to hypoxia positive regulation of protein localization to nucleus negative regulation of stem cell population maintenance positive regulation of stem cell population maintenance positive regulation of reactive oxygen species biosynthetic process positive regulation of TORC1 signaling	00514
1435222_at	Foxp1	forkhead box P1	6	-98925341, -98925341, -98925341, -98925341	BM220880	108655	301	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific core promoter sequence-specific DNA binding transcription coregulator binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific positive regulation of mesenchymal cell proliferation pre-B cell differentiation positive regulation of immunoglobulin production negative regulation of B cell apoptotic process DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleus regulation of DNA-templated transcription regulation of transcription by RNA polymerase II transcription by RNA polymerase II DNA damage response heart development skeletal muscle tissue development motor neuron axon guidance embryo development embryo development regulation of gene expression positive regulation of endothelial cell migration negative regulation of gene expression ventral spinal cord development osteoclast differentiation lung development response to lipopolysaccharide regulation of interleukin-1 beta production regulation of interleukin-12 production regulation of tumor necrosis factor production positive regulation of interleukin-21 production immunoglobulin V(D)J recombination osteoclast development macrophage activation monocyte activation endothelial cell activation identical protein binding identical protein binding sequence-specific DNA binding protein self-association regulation of monocyte differentiation negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II metal ion binding positive regulation of smooth muscle cell proliferation smooth muscle tissue development positive regulation of epithelial cell proliferation nuclear androgen receptor binding regulation of inflammatory response positive regulation of B cell receptor signaling pathway cardiac muscle cell differentiation regulation of cardiac muscle cell proliferation regulation of cardiac muscle cell proliferation negative regulation of androgen receptor signaling pathway negative regulation of cell growth involved in cardiac muscle cell development lung secretory cell differentiation T follicular helper cell differentiation innate vocalization behavior regulation of action potential regulation of defense response to bacterium regulation of lung goblet cell differentiation negative regulation of lung goblet cell differentiation regulation of macrophage colony-stimulating factor production positive regulation of hydrogen peroxide-mediated programmed cell death regulation of endothelial tube morphogenesis cellular response to ionomycin sequence-specific double-stranded DNA binding regulation of chemokine (C-X-C motif) ligand 2 production
1426473_at	Dnajc9	DnaJ heat shock protein family (Hsp40) member C9	14	-20384637	BM942465	108671	26	extracellular space nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol plasma membrane nucleosome assembly membrane heat shock protein binding heat shock protein binding positive regulation of ATP-dependent activity histone binding protein-folding chaperone binding protein folding chaperone complex
1435996_at	Card11	caspase recruitment domain family, member 11	5	-140872998	AV095659	108723	92	immunological synapse immune system process immunoglobulin production protein binding cytoplasm cytoplasm plasma membrane plasma membrane plasma membrane signal transduction canonical NF-kappaB signal transduction membrane B cell differentiation positive regulation of B cell proliferation T cell costimulation CBM complex interleukin-2 production positive regulation of interleukin-2 production positive regulation of interleukin-2 production CD4-positive, alpha-beta T cell proliferation TORC1 signaling B cell proliferation T cell activation regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction protein self-association thymic T cell selection membrane raft regulation of B cell differentiation regulation of T cell differentiation lymphocyte activation homeostasis of number of cells CARD domain binding CARD domain binding regulation of immune response positive regulation of T cell receptor signaling pathway positive regulation of T cell receptor signaling pathway positive regulation of T cell activation positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity protein homooligomerization positive regulation of CD4-positive, alpha-beta T cell proliferation	04660 04662
1437152_at	Mex3b	mex3 RNA binding family member B	7	82867332	BG072837	108797	22	P-body nucleic acid binding RNA binding nucleus nucleoplasm cytoplasm cytosol phagocytosis positive regulation of cell-cell adhesion GTPase activating protein binding positive regulation of GTPase activity metal ion binding positive regulation of phagocytosis establishment of localization in cell protein localization to cell cortex cell-cell adhesion
1456541_x_at	Atad3a	ATPase family, AAA domain containing 3A	4	-155740639	BB357220	108888	53	nucleotide binding protein binding ATP binding mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrion organization membrane ATP hydrolysis activity mitochondrial nucleoid identical protein binding
1426897_at	Rcc2	regulator of chromosome condensation 2	4	140701472	AV122997	108911	37	chromosome, centromeric region guanyl-nucleotide exchange factor activity nucleus chromosome cytoplasm cytoskeleton microtubule plasma membrane cell cycle integrin-mediated signaling pathway microtubule binding regulation of fibroblast migration positive regulation of G2/M transition of mitotic cell cycle membrane membrane protein kinase binding protein domain specific binding regulation of cell migration midbody small GTPase binding small GTPase binding small GTPase binding early endosome membrane negative regulation of GTPase activity negative regulation of GTPase activity negative regulation of GTPase activity chromosome, centromeric core domain establishment of protein localization focal adhesion assembly cell division negative regulation of focal adhesion assembly positive regulation of attachment of spindle microtubules to kinetochore chromosome passenger complex localization to kinetochore activation of GTPase activity negative regulation of substrate adhesion-dependent cell spreading regulation of ruffle assembly regulation of ruffle assembly mitotic spindle midzone
1433776_at	Lhfpl6	LHFPL tetraspan subfamily member 6	3	53041546	AV149705	108927	16	molecular_function biological_process membrane membrane
1438487_s_at	Zzz3	zinc finger, ZZ domain containing 3	3	152396683, 152396002, 152395472	BB724567	108946	28	DNA binding nucleus nucleoplasm nucleolus chromatin organization regulation of DNA-templated transcription regulation of transcription by RNA polymerase II zinc ion binding methylated histone binding regulation of embryonic development metal ion binding regulation of cell division regulation of cell division regulation of cell cycle regulation of cell cycle lysine-acetylated histone binding mitotic spindle regulation of tubulin deacetylation histone reader activity ATAC complex ATAC complex
1454850_at	Tbc1d10c	TBC1 domain family, member 10c	19	-4184356	AV060417	108995	21	GTPase activator activity GTPase activator activity plasma membrane filopodium membrane calcineurin-NFAT signaling cascade B cell activation retrograde transport, endosome to Golgi negative regulation of B cell activation negative regulation of B cell activation ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade negative regulation of calcineurin-NFAT signaling cascade activation of GTPase activity
1440202_at	5930412I24Rik	RIKEN cDNA 5930412I24 gene	13		BB036159	109206	1	molecular_function cellular_component biological_process
1427957_at	Adtrp	androgen dependent TFPI regulating protein	13	-41763147, -41763147	AI256077	109254	16	positive regulation of protein phosphorylation cell migration involved in sprouting angiogenesis negative regulation of leukocyte migration negative regulation of extracellular matrix constituent secretion plasma membrane caveola lipid metabolic process cell surface positive regulation of gene expression endomembrane system membrane hydrolase activity negative regulation of blood coagulation long-chain fatty acid catabolic process negative regulation of protein secretion cellular response to oxidised low-density lipoprotein particle stimulus negative regulation of leukocyte cell-cell adhesion negative regulation of lymphocyte migration
1424108_at	Glo1	glyoxalase 1	17	-30592861	BC024663	109801	110	lactoylglutathione lyase activity lactoylglutathione lyase activity nucleoplasm cytosol plasma membrane regulation of transcription by RNA polymerase II glutathione metabolic process zinc ion binding zinc ion binding methylglyoxal metabolic process lyase activity methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione osteoclast differentiation negative regulation of apoptotic process metal ion binding	00620
1417741_at	Pygl	liver glycogen phosphorylase	12	-70190814	NM_133198	110095	42	nucleotide binding purine nucleobase binding catalytic activity 1,4-alpha-oligoglucan phosphorylase activity protein binding ATP binding glucose binding cytoplasm cytoplasm carbohydrate metabolic process glycogen metabolic process glycogen catabolic process glycogen catabolic process glycogen catabolic process 5-phosphoribose 1-diphosphate biosynthetic process metabolic process glycogen phosphorylase activity glycogen phosphorylase activity glycogen phosphorylase activity response to bacterium AMP binding transferase activity glycosyltransferase activity vitamin binding pyridoxal phosphate binding pyridoxal phosphate binding carbohydrate binding bile acid binding glucose homeostasis identical protein binding necroptotic process linear malto-oligosaccharide phosphorylase activity SHG alpha-glucan phosphorylase activity	00500 04910
1439141_at	Gpr18	G protein-coupled receptor 18	14	-121911433	BG145550	110168	27	CD8-positive, alpha-beta intraepithelial T cell differentiation CD8-positive, alpha-beta intraepithelial T cell differentiation CD8-positive, gamma-delta intraepithelial T cell differentiation CD8-positive, gamma-delta intraepithelial T cell differentiation negative regulation of leukocyte chemotaxis G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane cytoplasmic vesicle negative regulation of tumor necrosis factor production positive regulation of Rho protein signal transduction
1437380_x_at	Pgd	phosphogluconate dehydrogenase	4	-149149990, -149149990	BB558114	110208	56	phosphogluconate dehydrogenase (decarboxylating) activity phosphogluconate dehydrogenase (decarboxylating) activity phosphogluconate dehydrogenase (decarboxylating) activity cytoplasm cytosol cytosol pentose-phosphate shunt NADP metabolic process phosphogluconate 2-dehydrogenase activity pentose-phosphate shunt, oxidative branch pentose-phosphate shunt, oxidative branch pentose-phosphate shunt, oxidative branch oxidoreductase activity pentose biosynthetic process D-gluconate metabolic process carbohydrate binding carboxylic acid binding D-gluconate catabolic process NADP binding NADP binding	00030 00480 01100
1448856_a_at	Msra	methionine sulfoxide reductase A	14	-64122620, -64122620, -64122620, -64122620, -64122620	NM_026322	110265	84	nucleus nucleoplasm cytoplasm mitochondrion cytosol plasma membrane peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity peptide-methionine (S)-S-oxide reductase activity actin cytoskeleton membrane oxidoreductase activity midbody cellular response to oxidative stress L-methionine-(S)-S-oxide reductase activity intracellular membrane-bounded organelle
1437993_x_at	Qdpr	quinoid dihydropteridine reductase	5	-45434031	BB221333	110391	48	6,7-dihydropteridine reductase activity 6,7-dihydropteridine reductase activity cytoplasm cytoplasm mitochondrion L-phenylalanine catabolic process tetrahydrobiopterin biosynthetic process tetrahydrobiopterin biosynthetic process oxidoreductase activity identical protein binding NADPH binding NADPH binding NADH binding NADH binding	00790 01100
1417185_at	Ly6a	lymphocyte antigen 6 family member A	15	-74994876	BC002070	110454	192	protein binding intracellular anatomical structure plasma membrane plasma membrane response to bacterium external side of plasma membrane membrane acetylcholine receptor inhibitor activity acetylcholine receptor binding acetylcholine receptor signaling pathway side of membrane
1454843_at	Prps2	phosphoribosyl pyrophosphate synthetase 2	X	-167346319	BM934034	110639	26	nucleotide binding magnesium ion binding ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase complex ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ribose phosphate diphosphokinase activity ATP binding ATP binding cytoplasm cytosol 5-phosphoribose 1-diphosphate biosynthetic process 5-phosphoribose 1-diphosphate biosynthetic process 5-phosphoribose 1-diphosphate biosynthetic process 5-phosphoribose 1-diphosphate biosynthetic process pentose-phosphate shunt purine nucleotide biosynthetic process AMP biosynthetic process ribonucleoside monophosphate biosynthetic process nucleotide biosynthetic process AMP binding kinase activity phosphorylation transferase activity GDP binding carbohydrate binding protein-containing complex identical protein binding ADP binding cellular biosynthetic process metal ion binding	00030 00230 01100
1428719_at	Iglc2	immunoglobulin lambda constant 2	16		AK008551	110786	29	antigen binding extracellular region plasma membrane immunoglobulin mediated immune response IgG immunoglobulin complex IgG immunoglobulin complex
1427233_at	Tshz1	teashirt zinc finger family member 1	18	-84011626, -84011626	AV291373	110796	52	DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding DNA binding protein binding nucleus nucleus regulation of transcription by RNA polymerase II multicellular organism development anterior/posterior pattern specification regulation of gene expression middle ear morphogenesis metal ion binding soft palate development
1452430_s_at	Srsf1	serine and arginine-rich splicing factor 1	11	88047372	X66091	110809	110	alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome mRNA 5'-splice site recognition in utero embryonic development nucleic acid binding RNA binding mRNA binding mRNA binding mRNA binding protein binding nucleus nucleus nucleus nucleoplasm spliceosomal complex cytoplasm mRNA processing RNA splicing RNA splicing nuclear speck nuclear speck nuclear speck signal transduction involved in regulation of gene expression signal transduction involved in regulation of gene expression positive regulation of RNA splicing protein localization to nucleus exon-exon junction complex protein kinase B binding regulation of RNA splicing DNA topoisomerase binding mRNA stabilization mRNA stabilization RS domain binding mRNA transport cardiac muscle contraction catalytic step 2 spliceosome cellular response to interleukin-17 interleukin-17-mediated signaling pathway interleukin-17-mediated signaling pathway molecular function regulator activity protein localization to P-body	03040
1418231_at	Lims1	LIM and senescent cell antigen-like domains 1	10	58323546, 58351962, 58394372, 58371453	BC005621	110829	73	protein binding cytoplasm plasma membrane cell-cell junction cell-cell junction focal adhesion focal adhesion focal adhesion cell-matrix adhesion establishment or maintenance of cell polarity integrin-mediated signaling pathway zinc ion binding positive regulation of gene expression positive regulation of cell-substrate adhesion membrane protein kinase binding protein-containing complex tumor necrosis factor-mediated signaling pathway chordate embryonic development positive regulation of canonical NF-kappaB signal transduction positive regulation of GTPase activity protein-containing complex binding establishment of protein localization cell-cell junction organization cell-cell junction organization negative regulation of DNA-templated transcription metal ion binding perinuclear region of cytoplasm positive regulation of focal adhesion assembly neural precursor cell proliferation anchoring junction hepatocyte apoptotic process cell-cell adhesion cell-cell adhesion positive regulation of substrate adhesion-dependent cell spreading positive regulation of substrate adhesion-dependent cell spreading negative regulation of hepatocyte apoptotic process negative regulation of cholangiocyte proliferation cholangiocyte proliferation negative regulation of neural precursor cell proliferation negative regulation of hepatocyte proliferation positive regulation of integrin-mediated signaling pathway positive regulation of integrin-mediated signaling pathway
1448138_at	Ptpa	protein phosphatase 2 protein activator	2	30441852, 30416049	NM_138748	110854	33	protein phosphatase type 2A complex protein phosphatase type 2A complex nucleotide binding peptidyl-prolyl cis-trans isomerase activity peptidyl-prolyl cis-trans isomerase activity phosphoprotein phosphatase activity signaling receptor binding ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm mitotic spindle organization protein tyrosine phosphatase activator activity protein tyrosine phosphatase activator activity isomerase activity phosphatase activator activity protein phosphatase regulator activity negative regulation of phosphoprotein phosphatase activity positive regulation of phosphoprotein phosphatase activity calcium channel complex positive regulation of protein dephosphorylation negative regulation of protein dephosphorylation protein homodimerization activity positive regulation of apoptotic process regulation of phosphoprotein phosphatase activity protein phosphatase 2A binding ATPase complex
1421840_at	Abca1	ATP-binding cassette, sub-family A member 1	4	-53030788	BB144704	11303	455	nucleotide binding peptide secretion signaling receptor binding protein binding ATP binding phospholipid transporter activity phospholipid transporter activity phospholipid transporter activity endosome Golgi apparatus plasma membrane plasma membrane protein lipidation phagocytosis, engulfment lysosome organization G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway high-density lipoprotein particle binding cholesterol metabolic process cholesterol metabolic process protein transmembrane transporter activity protein secretion protein secretion external side of plasma membrane cell surface positive regulation of cholesterol efflux phospholipid transport membrane endosomal transport basolateral plasma membrane ATP hydrolysis activity syntaxin binding signal release signal release endocytic vesicle cholesterol transport phosphatidylcholine binding small GTPase binding intracellular cholesterol transport regulation of Cdc42 protein signal transduction cholesterol efflux cholesterol efflux cholesterol efflux phospholipid efflux phospholipid efflux phospholipid efflux phospholipid efflux apolipoprotein binding apolipoprotein A-I binding apolipoprotein A-I receptor activity high-density lipoprotein particle assembly response to laminar fluid shear stress lipoprotein metabolic process lipoprotein biosynthetic process lipoprotein biosynthetic process ATPase-coupled transmembrane transporter activity ATPase-coupled transmembrane transporter activity cholesterol homeostasis intracellular membrane-bounded organelle intracellular membrane-bounded organelle reverse cholesterol transport reverse cholesterol transport membrane raft phospholipid translocation phospholipid translocation phagocytic vesicle sphingolipid floppase activity perinuclear region of cytoplasm ATPase binding establishment of localization in cell transmembrane transport phospholipid homeostasis platelet dense granule organization cellular response to lipopolysaccharide cellular response to retinoic acid protein transmembrane transport positive regulation of high-density lipoprotein particle assembly phosphatidylcholine floppase activity phosphatidylcholine floppase activity phosphatidylserine floppase activity phosphatidylserine floppase activity intracellular vesicle cholesterol transfer activity cholesterol transfer activity cholesterol transfer activity export across plasma membrane ATPase-coupled intramembrane lipid transporter activity floppase activity ABC-type transporter activity	02010 04975
1428847_a_at	Macf1	microtubule-actin crosslinking factor 1	4	-123349632	BM248206	11426	95	mesoderm formation actin binding actin binding structural molecule activity calcium ion binding protein binding cytoplasm cytoplasm cytoplasm Golgi apparatus cytoskeleton microtubule microtubule microtubule intermediate filament plasma membrane cell cortex post-translational protein targeting to endoplasmic reticulum membrane establishment or maintenance of cell polarity microtubule binding protein localization regulation of epithelial cell migration postsynaptic density actin cytoskeleton actin cytoskeleton microtubule cytoskeleton membrane membrane Wnt signaling pathway Wnt signaling pathway cell migration ATP hydrolysis activity positive regulation of Wnt signaling pathway positive regulation of Wnt signaling pathway regulation of cell migration ruffle membrane regulation of microtubule-based process regulation of microtubule-based process regulation of microtubule-based process wound healing wound healing cell projection Golgi to plasma membrane protein transport intermediate filament cytoskeleton organization intermediate filament cytoskeleton organization positive regulation of axon extension metal ion binding microtubule minus-end binding actin filament binding regulation of focal adhesion assembly regulation of focal adhesion assembly regulation of focal adhesion assembly regulation of neuron projection arborization
1424654_at	Acp2	acid phosphatase 2, lysosomal	2	91202911	BB022890	11432	43	skeletal system development phosphotyrosine residue binding acid phosphatase activity acid phosphatase activity acid phosphatase activity acid phosphatase activity phosphoprotein phosphatase activity lysosome lysosome lysosome lysosome lysosome organization lysosome organization response to organic substance membrane dephosphorylation hydrolase activity autophagic cell death	00740 04142
1431609_a_at	Acp5	acid phosphatase 5, tartrate resistant	9	-22126726, -22126726, -22126726	AK008391	11433	113	acid phosphatase activity acid phosphatase activity acid phosphatase activity acid phosphatase activity extracellular space lysosome lysosome nitric oxide biosynthetic process negative regulation of cell adhesion ferrous iron binding ferrous iron binding ferric iron binding ferric iron binding macrophage cytokine production negative regulation of macrophage cytokine production dephosphorylation hydrolase activity positive regulation of cell migration response to lipopolysaccharide interleukin-1 beta production interleukin-12 production tumor necrosis factor production negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production negative regulation of tumor necrosis factor production negative regulation of superoxide anion generation response to cytokine superoxide anion generation negative regulation of nitric oxide biosynthetic process bone resorption bone resorption metal ion binding negative regulation of inflammatory response defense response to Gram-positive bacterium bone morphogenesis	00740 04142 04380 05323
1429379_at	Lyve1	lymphatic vessel endothelial hyaluronan receptor 1	7	-110850606	AV124537	114332	389	positive regulation of cellular extravasation transmembrane signaling receptor activity transmembrane signaling receptor activity hyaluronic acid binding hyaluronic acid binding hyaluronic acid binding plasma membrane plasma membrane plasma membrane glycosaminoglycan catabolic process receptor-mediated endocytosis receptor-mediated endocytosis cell adhesion membrane hyaluronan catabolic process cargo receptor activity cargo receptor activity cell periphery
1416871_at	Adam8	a disintegrin and metallopeptidase domain 8	7	-139978931	NM_007403	11501	76	cell morphogenesis angiogenesis podosome podosome leukocyte migration involved in inflammatory response positive regulation of acute inflammatory response positive regulation of cellular extravasation positive regulation of cellular extravasation metalloendopeptidase activity metalloendopeptidase activity integrin binding calcium ion binding protein binding cytoplasm plasma membrane plasma membrane proteolysis proteolysis inflammatory response inflammatory response cell-matrix adhesion canonical NF-kappaB signal transduction peptidase activity metallopeptidase activity metallopeptidase activity zinc ion binding cell surface positive regulation of epithelial to mesenchymal transition membrane hydrolase activity regulation of cell-cell adhesion regulation of cell-cell adhesion phagolysosome dense core granule membrane positive regulation of T cell differentiation in thymus specific granule positive regulation of MAPK cascade negative regulation of neuron apoptotic process blood vessel endothelial cell migration positive regulation of innate immune response regulation of osteoclast differentiation positive regulation of bone resorption positive regulation of bone resorption positive regulation of cell adhesion metal ion binding lymphocyte chemotaxis tissue morphogenesis positive regulation of inflammatory response cell adhesion molecule binding cell adhesion molecule binding cell adhesion molecule binding positive regulation of membrane protein ectodomain proteolysis positive regulation of membrane protein ectodomain proteolysis positive regulation of membrane protein ectodomain proteolysis positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction membrane fusion positive regulation of thymocyte apoptotic process tertiary granule alpha9-beta1 integrin-ADAM8 complex cellular response to hypoxia osteoclast fusion cell-cell adhesion positive regulation of transforming growth factor beta1 activation positive regulation of tumor necrosis factor (ligand) superfamily member 11 production positive regulation of neutrophil extravasation negative regulation of thymocyte aggregation positive regulation of T cell migration positive regulation of fibronectin-dependent thymocyte migration positive regulation of eosinophil migration
1450065_at	Adcy7	adenylate cyclase 7	8	88282991, 88289065, 88272402, 88294203	NM_007406	11513	34	nucleotide binding regulation of adaptive immune response adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity adenylate cyclase activity ATP binding plasma membrane cAMP biosynthetic process cAMP biosynthetic process cAMP biosynthetic process adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway activation of adenylate cyclase activity adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway cyclic nucleotide biosynthetic process membrane lyase activity phosphorus-oxygen lyase activity intracellular signal transduction metal ion binding cellular response to lithium ion cellular response to ethanol negative regulation of cytokine production involved in inflammatory response	00230 04020 04062 04114 04270 04540 04912 04914 04916 04970 04971 04972 04976 05414
1435287_at	Add2	adducin 2	6	86028680, 86078047, 86028680, 86078047	AV298858	11519	67	actin binding structural constituent of cytoskeleton calmodulin binding cytoplasm cytoskeleton cytoskeleton plasma membrane plasma membrane monoatomic ion transport synapse assembly synapse assembly synapse assembly F-actin capping protein complex postsynaptic density postsynaptic density membrane protein kinase binding hemopoiesis spectrin binding cytoplasmic vesicle positive regulation of protein binding protein homodimerization activity plasma membrane raft protein heterodimerization activity protein dimerization activity leukocyte migration leukocyte tethering or rolling actin filament binding actin filament binding barbed-end actin filament capping barbed-end actin filament capping actin filament bundle assembly protein-containing complex assembly postsynapse glutamatergic synapse
1448318_at	Plin2	perilipin 2	4	-86656564	NM_007408	11520	154	protein binding nucleus cytoplasm lipid droplet lipid droplet lipid droplet lipid droplet cytosol cytosol cytosol plasma membrane positive regulation of sequestering of triglyceride long-chain fatty acid transport membrane lipid storage lipid storage lipid storage cellular response to glucose starvation lipid droplet disassembly
1435368_a_at	Parp1	poly (ADP-ribose) polymerase family, member 1	1	180568890	BB767586	11545	673	negative regulation of transcription by RNA polymerase II telomere maintenance chromatin chromatin immune system process DNA binding chromatin binding chromatin binding damaged DNA binding catalytic activity NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity protein binding nucleus nucleus nucleus nuclear envelope nucleoplasm nucleoplasm transcription regulator complex chromosome nucleolus nucleolus nucleolus cytoplasm mitochondrion cytosol DNA metabolic process DNA repair DNA repair DNA repair base-excision repair double-strand break repair double-strand break repair double-strand break repair apoptotic process DNA damage response mitochondrion organization mitochondrion organization transforming growth factor beta receptor signaling pathway metabolic process zinc ion binding positive regulation of cardiac muscle hypertrophy carbohydrate biosynthetic process protein autoprocessing nuclear body transferase activity glycosyltransferase activity nucleotidyltransferase activity enzyme binding protein kinase binding signal transduction involved in regulation of gene expression nuclear estrogen receptor binding DNA ADP-ribosylation nucleosome binding ubiquitin protein ligase binding mitochondrial DNA metabolic process negative regulation of interleukin-17 production positive regulation of DNA-templated transcription, elongation cellular response to insulin stimulus regulation of protein localization protein-containing complex protein-containing complex protein-DNA complex positive regulation of intracellular estrogen receptor signaling pathway negative regulation of transcription elongation by RNA polymerase II cellular response to oxidative stress cellular response to UV site of double-strand break protein modification process regulation of growth rate identical protein binding protein homodimerization activity histone deacetylase binding positive regulation of canonical NF-kappaB signal transduction mitochondrial DNA repair nuclear replication fork regulation of DNA methylation innate immune response regulation of circadian sleep/wake cycle, non-REM sleep negative regulation of innate immune response negative regulation of innate immune response negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II decidualization metal ion binding behavioral response to cocaine regulation of catalytic activity voluntary musculoskeletal movement NAD binding positive regulation of mitochondrial depolarization positive regulation of SMAD protein signal transduction positive regulation of necroptotic process RNA polymerase II-specific DNA-binding transcription factor binding protein poly-ADP-ribosylation protein poly-ADP-ribosylation protein poly-ADP-ribosylation protein auto-ADP-ribosylation R-SMAD binding protein localization to chromatin cellular response to superoxide replication fork reversal site of DNA damage site of DNA damage NAD DNA ADP-ribosyltransferase activity transcription regulator activator activity NAD+-protein-serine ADP-ribosyltransferase activity NAD+- protein-aspartate ADP-ribosyltransferase activity NAD+- protein-aspartate ADP-ribosyltransferase activity NAD+-protein-glutamate ADP-ribosyltransferase activity NAD+-protein-glutamate ADP-ribosyltransferase activity NAD+-protein-glutamate ADP-ribosyltransferase activity NAD+-protein-tyrosine ADP-ribosyltransferase activity NAD+-protein-histidine ADP-ribosyltransferase activity NAD+-histone H2BS6 serine ADP-ribosyltransferase activity NAD+-histone H3S10 serine ADP-ribosyltransferase activity NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity negative regulation of cGAS/STING signaling pathway positive regulation of protein localization to nucleus regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway regulation of single strand break repair positive regulation of single strand break repair positive regulation of single strand break repair negative regulation of adipose tissue development negative regulation of telomere maintenance via telomere lengthening cellular response to amyloid-beta positive regulation of myofibroblast differentiation regulation of base-excision repair positive regulation of double-strand break repair via homologous recombination cellular response to nerve growth factor stimulus NAD+-protein ADP-ribosyltransferase activity NAD+-protein ADP-ribosyltransferase activity NAD+-protein ADP-ribosyltransferase activity ATP generation from poly-ADP-D-ribose negative regulation of ATP biosynthetic process	03410
1449383_at	Adss1	adenylosuccinate synthase 1	12	112620046	NM_007421	11565	32	nucleotide binding GTPase activity adenylosuccinate synthase activity adenylosuccinate synthase activity adenylosuccinate synthase activity protein binding GTP binding cytoplasm cytoplasm cytoplasm purine nucleotide metabolic process purine nucleotide biosynthetic process AMP biosynthetic process aspartate metabolic process membrane ligase activity identical protein binding 'de novo' AMP biosynthetic process AMP salvage AMP salvage IMP metabolic process IMP metabolic process metal ion binding actin filament binding	00230 00250 01100
1449838_at	Crisp3	cysteine-rich secretory protein 3	17	-40221776	NM_009639	11572	18	extracellular region extracellular space cytoplasmic vesicle
1418204_s_at	Aif1	allograft inflammatory factor 1	17	-35170985	NM_019467	11629	273	ruffle microglial cell activation phagocytic cup positive regulation of protein phosphorylation actin binding calcium ion binding calcium ion binding protein binding nucleus nucleus cytoplasm cytoplasm cytosol cytoskeleton actin filament actin filament plasma membrane phagocytosis, engulfment positive regulation of cell population proliferation negative regulation of gene expression positive regulation of muscle hyperplasia membrane Rac protein signal transduction lamellipodium lamellipodium actin filament polymerization parallel actin filament bundle assembly positive regulation of cell migration ruffle membrane ruffle membrane ruffle membrane positive regulation of chemokine production positive regulation of interleukin-6 production cellular response to oxidative stress positive regulation of T cell proliferation cell projection negative regulation of apoptotic process perikaryon positive regulation of nitric oxide biosynthetic process metal ion binding perinuclear region of cytoplasm positive regulation of smooth muscle cell proliferation negative regulation of smooth muscle cell proliferation positive regulation of chemotaxis actin filament binding actin filament binding actin filament binding actin filament bundle assembly actin filament bundle assembly actin filament bundle assembly actin crosslink formation negative regulation of smooth muscle cell chemotaxis positive regulation of smooth muscle cell chemotaxis positive regulation of mononuclear cell migration positive regulation of monocyte chemotaxis positive regulation of fibroblast growth factor production ruffle assembly ruffle assembly ruffle assembly glial cell projection positive regulation of G1/S transition of mitotic cell cycle positive regulation of T cell migration
1452016_at	Alox5ap	arachidonate 5-lipoxygenase activating protein	5	149265003	BC026209	11690	44	leukotriene production involved in inflammatory response positive regulation of acute inflammatory response arachidonate 5-lipoxygenase activity glutathione transferase activity leukotriene-C4 synthase activity glutathione peroxidase activity protein binding nucleus nuclear envelope nuclear envelope endoplasmic reticulum endoplasmic reticulum leukotriene metabolic process enzyme activator activity membrane leukotriene biosynthetic process leukotriene biosynthetic process leukotriene biosynthetic process leukotriene biosynthetic process lipoxygenase pathway enzyme binding nuclear membrane identical protein binding protein-containing complex binding arachidonic acid binding protein homotrimerization cellular response to calcium ion
1418685_at	Tirap	toll-interleukin 1 receptor (TIR) domain-containing adaptor protein	9	-35184390, -35184390, -35184390	NM_054096	117149	130	immune system process protein kinase C binding protein binding phosphatidylinositol-4,5-bisphosphate binding cytoplasm cytoplasm plasma membrane plasma membrane inflammatory response signal transduction cell surface receptor signaling pathway cell surface receptor signaling pathway response to bacterium cell surface macrophage cytokine production membrane myeloid cell differentiation endocytic vesicle positive regulation of B cell proliferation extrinsic component of cytoplasmic side of plasma membrane positive regulation of protein-containing complex assembly response to lipopolysaccharide ruffle membrane tumor necrosis factor production regulation of interferon-beta production regulation of interleukin-15 production positive regulation of interleukin-12 production positive regulation of interleukin-15 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production regulation of stress-activated MAPK cascade positive regulation of toll-like receptor 2 signaling pathway positive regulation of toll-like receptor 3 signaling pathway toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway positive regulation of toll-like receptor 4 signaling pathway signaling adaptor activity signaling adaptor activity Toll-like receptor 4 binding Toll-like receptor 4 binding Toll-like receptor 2 binding Toll-like receptor 2 binding Toll-like receptor 2 binding TIRAP-dependent toll-like receptor 4 signaling pathway identical protein binding identical protein binding positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of JUN kinase activity innate immune response regulation of innate immune response positive regulation of innate immune response positive regulation of JNK cascade defense response to Gram-positive bacterium positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity molecular adaptor activity positive regulation of macrophage cytokine production positive regulation of ERK1 and ERK2 cascade 3'-UTR-mediated mRNA stabilization cellular response to bacterial lipopeptide cellular response to lipoteichoic acid positive regulation of neutrophil chemotaxis positive regulation of chemokine (C-X-C motif) ligand 1 production positive regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of chemokine (C-X-C motif) ligand 2 production	04620
1460197_a_at	Steap4	STEAP family member 4	5	7960471	NM_054098	117167	39	nucleoplasm endosome endosome Golgi apparatus plasma membrane plasma membrane plasma membrane plasma membrane monoatomic ion transport iron ion transport cupric reductase activity cupric reductase activity electron transfer activity copper ion import copper ion import membrane oxidoreductase activity heme binding iron import into cell fat cell differentiation metal ion binding ferric-chelate reductase (NADPH) activity ferric-chelate reductase (NADPH) activity ferric-chelate reductase (NADPH) activity protein homotrimerization FAD binding iron ion import across cell outer membrane
1422573_at	Ampd3	adenosine monophosphate deaminase 3	7	110772603, 110768205, 110773635, 110768621	D85596	11717	39	AMP deaminase activity AMP deaminase activity AMP deaminase activity AMP deaminase activity cytosol IMP biosynthetic process IMP biosynthetic process IMP biosynthetic process AMP catabolic process nucleotide metabolic process purine ribonucleoside monophosphate biosynthetic process hydrolase activity deaminase activity IMP salvage erythrocyte homeostasis ADP metabolic process ADP catabolic process AMP metabolic process AMP metabolic process ATP metabolic process ATP metabolic process GTP metabolic process GTP metabolic process metal ion binding energy homeostasis	00230 01100
1425718_a_at	Ivns1abp	influenza virus NS1A binding protein	1	151344485, 151344497, 151344497	BC004092	117198	29	protein binding nucleus cytoplasm cytosol cytoskeleton RNA splicing response to virus negative regulation of protein ubiquitination intrinsic apoptotic signaling pathway negative regulation of intrinsic apoptotic signaling pathway
1450627_at	Ank	progressive ankylosis	15	27466676	NM_020332	11732	84	inorganic phosphate transmembrane transporter activity inorganic phosphate transmembrane transporter activity ATP transmembrane transporter activity extracellular region plasma membrane plasma membrane gene expression gene expression phosphate ion transmembrane transporter activity membrane membrane bone mineralization bone mineralization regulation of bone mineralization inorganic diphosphate transmembrane transporter activity inorganic diphosphate transmembrane transporter activity inorganic diphosphate transmembrane transporter activity inorganic diphosphate transport phosphate ion transmembrane transport muscle cell cellular homeostasis phosphate ion homeostasis calcium ion homeostasis diphosphate metabolic process diphosphate metabolic process cementum mineralization cementum mineralization inhibition of non-skeletal tissue mineralization inhibition of non-skeletal tissue mineralization response to sodium phosphate ATP export
1418468_at	Anxa11	annexin A11	14	25842154	NM_013469	11744	34	phosphatidylserine binding calcium ion binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding nucleus nuclear envelope nucleoplasm cytoplasm cytoplasm cytoplasm spindle cytosol cytoskeleton plasma membrane phagocytosis cell cycle phosphatidylethanolamine binding midbody cytokinetic process cytokinetic process specific granule azurophil granule S100 protein binding phagocytic vesicle calcium-dependent protein binding cell division response to calcium ion collagen-containing extracellular matrix
1460330_at	Anxa3	annexin A3	5	96793384	AW702161	11745	33	phosphatidylserine binding phospholipase inhibitor activity calcium ion binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding cytoplasm cytoplasm plasma membrane plasma membrane phagocytosis positive regulation of endothelial cell migration membrane phospholipase A2 inhibitor activity axon dendrite phagocytic vesicle membrane specific granule defense response to bacterium neuronal cell body neutrophil degranulation positive regulation of angiogenesis calcium-dependent protein binding positive regulation of DNA metabolic process positive regulation of DNA-binding transcription factor activity collagen-containing extracellular matrix
1421223_a_at	Anxa4	annexin A4	6	-86736839, -86736839	NM_013471	11746	42	phosphatidylserine binding kidney development calcium ion binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding nucleus cytoplasm cytoplasm plasma membrane plasma membrane regulation of transcription by RNA polymerase II Notch signaling pathway cell surface vesicle membrane membrane apical plasma membrane cytoplasmic vesicle nuclear membrane negative regulation of NF-kappaB transcription factor activity negative regulation of interleukin-8 production identical protein binding calcium-dependent protein binding perinuclear region of cytoplasm NF-kappaB binding collagen-containing extracellular matrix
1452342_at	Apbb2	amyloid beta precursor protein binding family B member 2	5	-66298724, -66298724	AW542721	11787	41	negative regulation of transcription by RNA polymerase II amyloid-beta binding amyloid-beta binding neuron migration protein binding nucleus nucleus cytoplasm cytoplasm endosome early endosome endoplasmic reticulum Golgi apparatus regulation of DNA-templated transcription smooth muscle contraction axon guidance transcription factor binding extracellular matrix organization maintenance of lens transparency positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of transcription by RNA polymerase II protein stabilization negative regulation of cell cycle phase transition
1435543_at	Apc	APC, WNT signaling pathway regulator	18	34247693, 34220983	BM124893	11789	1824	MAPK cascade MAPK cascade mitotic cytokinesis mitotic cytokinesis kinetochore cell fate specification kidney development endothelial cell proliferation endothelial cell proliferation negative regulation of endothelial cell proliferation negative regulation of endothelial cell proliferation hair follicle development protease binding protein binding nucleus nucleus cytoplasm cytoplasm Golgi apparatus centrosome cytoskeleton microtubule cytoplasmic microtubule plasma membrane adherens junction bicellular tight junction cell cortex apoptotic process DNA damage response microtubule depolymerization negative regulation of microtubule depolymerization negative regulation of microtubule depolymerization negative regulation of microtubule depolymerization metaphase/anaphase transition of mitotic cell cycle metaphase/anaphase transition of mitotic cell cycle mitotic spindle assembly checkpoint signaling cell adhesion establishment or maintenance of cell polarity pattern specification process pattern specification process nervous system development axonogenesis axonogenesis beta-catenin binding beta-catenin binding beta-catenin binding beta-catenin binding microtubule binding microtubule binding cell population proliferation cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation insulin receptor signaling pathway insulin receptor signaling pathway axis specification anterior/posterior pattern specification dorsal/ventral pattern formation proximal/distal pattern formation regulation of epithelial cell migration fibroblast migration positive regulation of fibroblast migration microtubule cytoskeleton membrane Wnt signaling pathway Wnt signaling pathway Wnt signaling pathway lateral plasma membrane catenin complex catenin complex cell migration cell migration cell migration stem cell population maintenance protein kinase regulator activity protein kinase binding protein kinase binding lamellipodium protein catabolic process negative regulation of Wnt signaling pathway negative regulation of Wnt signaling pathway regulation of cell migration positive regulation of cell migration axon dendrite growth cone growth cone synaptic vesicle membrane regulation of epithelial cell differentiation beta-catenin destruction complex beta-catenin destruction complex beta-catenin destruction complex positive regulation of microtubule polymerization cytoplasmic microtubule organization neuron projection development cell projection membrane positive regulation of pseudopodium assembly ubiquitin protein ligase binding nuclear membrane ruffle membrane regulation of microtubule-based process protein-containing complex T cell differentiation in thymus Scrib-APC-beta-catenin complex somatic stem cell population maintenance somatic stem cell population maintenance odontogenesis negative regulation of odontogenesis cell projection neuronal cell body positive regulation of apoptotic process negative regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process negative regulation of MAPK cascade negative regulation of MAPK cascade skin development axonal growth cone axonal growth cone neuron projection terminus canonical Wnt signaling pathway involved in negative regulation of apoptotic process canonical Wnt signaling pathway involved in positive regulation of apoptotic process fibroblast apoptotic process protein-containing complex binding gamma-catenin binding gamma-catenin binding regulation of cell differentiation regulation of cell differentiation positive regulation of cell differentiation regulation of osteoblast differentiation regulation of osteoclast differentiation positive regulation of protein catabolic process positive regulation of protein catabolic process positive regulation of protein catabolic process negative regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of cell adhesion muscle cell cellular homeostasis microtubule polymerization perinuclear region of cytoplasm thymus development epithelial cell proliferation epithelial cell proliferation negative regulation of epithelial cell proliferation negative regulation of epithelial cell proliferation microtubule plus-end binding microtubule plus-end binding regulation of nitrogen compound metabolic process chromosome organization chromosome organization cell division regulation of cell cycle positive regulation of cell division regulation of attachment of spindle microtubules to kinetochore regulation of attachment of spindle microtubules to kinetochore retina development in camera-type eye negative regulation of cardiac muscle cell proliferation canonical Wnt signaling pathway epithelial cell proliferation involved in prostate gland development negative regulation of epithelial cell proliferation involved in prostate gland development protein-containing complex assembly anchoring junction dynein complex binding dynein complex binding cell body fiber negative regulation of canonical Wnt signaling pathway negative regulation of canonical Wnt signaling pathway negative regulation of canonical Wnt signaling pathway positive regulation of cold-induced thermogenesis negative regulation of cell cycle G1/S phase transition epithelial cell apoptotic process negative regulation of epithelial cell apoptotic process negative regulation of acinar cell proliferation negative regulation of acinar cell proliferation positive regulation of protein localization to centrosome positive regulation of protein localization to centrosome acinar cell proliferation acinar cell proliferation negative regulation of G1/S transition of mitotic cell cycle regulation of glutamate metabolic process positive regulation of fibroblast apoptotic process	04310 04810 05200 05210 05213 05217
1449193_at	Cd5l	CD5 antigen-like	3	87357880	NM_009690	11801	54	immune system process serine-type endopeptidase activity extracellular region cytoplasm plasma membrane plasma membrane apoptotic process inflammatory response cell surface cell surface membrane regulation of complement activation zymogen activation positive regulation of complement-dependent cytotoxicity
1427442_a_at	App	amyloid beta precursor protein	16	-84954435	BC005490	11820	1463	G2/M transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II mitotic cell cycle RNA polymerase II cis-regulatory region sequence-specific DNA binding G protein-coupled receptor binding microglial cell activation response to yeast positive regulation of protein phosphorylation suckling behavior astrocyte activation involved in immune response chromatin binding serine-type endopeptidase inhibitor activity signaling receptor binding signaling receptor binding frizzled binding insulin receptor binding integrin binding protein binding extracellular region extracellular space nucleus nuclear envelope lumen cytoplasm cytoplasm mitochondrion lysosome endosome early endosome early endosome early endosome endoplasmic reticulum Golgi apparatus Golgi apparatus Golgi apparatus Golgi-associated vesicle plasma membrane plasma membrane plasma membrane clathrin-coated pit cell-cell junction regulation of transcription by RNA polymerase II regulation of translation protein phosphorylation intracellular copper ion homeostasis intracellular copper ion homeostasis endocytosis apoptotic process response to oxidative stress cell adhesion regulation of epidermal growth factor-activated receptor activity G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway Notch signaling pathway axonogenesis axonogenesis central nervous system development learning or memory learning memory memory mating behavior locomotory behavior synaptic vesicle axo-dendritic transport axo-dendritic transport heparin binding cholesterol metabolic process cholesterol metabolic process negative regulation of cell population proliferation associative learning adult locomotory behavior visual learning cell surface cell surface cell surface negative regulation of peptidase activity regulation of gene expression regulation of gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of protein kinase A signaling positive regulation of peptidyl-threonine phosphorylation positive regulation of G2/M transition of mitotic cell cycle microglia development membrane membrane membrane axon midline choice point recognition neuron remodeling dendrite development dendrite development peptidase activator activity calcium-mediated signaling antibacterial humoral response antifungal humoral response enzyme binding COPII-coated ER to Golgi transport vesicle neuron differentiation neuron differentiation extracellular matrix organization peptidase inhibitor activity axon axon growth cone signaling receptor activator activity signaling receptor activator activity signaling receptor activator activity forebrain development forebrain development neuron projection development cytoplasmic vesicle neuromuscular junction positive regulation of protein binding positive regulation of chemokine production positive regulation of type II interferon production positive regulation of interleukin-1 beta production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of superoxide anion generation protein-containing complex acetylcholine receptor binding positive regulation of peptidyl-serine phosphorylation regulation of toll-like receptor signaling pathway apolipoprotein binding very-low-density lipoprotein particle low-density lipoprotein particle intermediate-density lipoprotein particle high-density lipoprotein particle ionotropic glutamate receptor signaling pathway ciliary rootlet regulation of multicellular organism growth chemoattractant activity identical protein binding protein homodimerization activity cell projection neuron projection neuron projection positive regulation of apoptotic process ion binding receptor complex positive regulation of cysteine-type endopeptidase activity involved in apoptotic process regulation of protein binding regulation of protein binding heparan sulfate proteoglycan binding positive regulation of MAPK cascade positive regulation of neuron apoptotic process positive regulation of cAMP-mediated signaling cell body main axon innate immune response membrane raft membrane raft apical part of cell positive regulation of nitric oxide biosynthetic process negative regulation of neuron differentiation negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of G protein-coupled receptor signaling pathway positive regulation of glycolytic process positive regulation of mitotic cell cycle positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of JNK cascade metal ion binding ephrin receptor binding transition metal ion binding protein heterodimerization activity receptor ligand activity astrocyte activation regulation of long-term neuronal synaptic plasticity perinuclear region of cytoplasm perinuclear region of cytoplasm collateral sprouting in absence of injury presynaptic active zone presynaptic active zone positive regulation of inflammatory response regulation of peptidyl-tyrosine phosphorylation low-density lipoprotein particle receptor binding RAGE receptor binding regulation of synapse structure or activity synapse organization defense response to Gram-negative bacterium defense response to Gram-positive bacterium positive regulation of calcium-mediated signaling neuromuscular process controlling balance cognition positive regulation of membrane protein ectodomain proteolysis protein-folding chaperone binding positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity synaptic assembly at neuromuscular junction spindle midzone positive regulation of protein metabolic process protein homooligomerization protein tetramerization neuron apoptotic process neuron apoptotic process PTB domain binding smooth endoplasmic reticulum calcium ion homeostasis recycling endosome long-term synaptic potentiation positive regulation of protein tyrosine kinase activity antimicrobial humoral immune response mediated by antimicrobial peptide neuron cellular homeostasis protein trimerization positive regulation of ERK1 and ERK2 cascade endosome to plasma membrane transport vesicle response to interleukin-1 growth factor receptor binding cellular response to norepinephrine stimulus positive regulation of monocyte chemotaxis negative regulation of canonical Wnt signaling pathway astrocyte projection presynapse postsynapse modulation of excitatory postsynaptic potential neuronal dense core vesicle amyloid-beta complex regulation of spontaneous synaptic transmission cytoplasmic polyadenylation positive regulation of receptor binding negative regulation of protein localization to nucleus regulation of amyloid-beta clearance negative regulation of long-term synaptic potentiation positive regulation of long-term synaptic potentiation positive regulation of non-canonical NF-kappaB signal transduction negative regulation of miRNA transcription regulation of dendritic spine maintenance positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process regulation of acetylcholine-gated cation channel activity regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway negative regulation of blood circulation negative regulation of blood circulation positive regulation of G protein-coupled receptor internalization positive regulation of endothelin production positive regulation of endothelin production positive regulation of protein import cellular response to amyloid-beta regulation of presynapse assembly positive regulation of response to endoplasmic reticulum stress regulation of amyloid fibril formation positive regulation of amyloid fibril formation regulation of response to calcium ion amyloid fibril formation neuron projection maintenance growth cone lamellipodium lipoprotein particle growth cone filopodium positive regulation of T cell migration positive regulation of excitatory postsynaptic potential positive regulation of extrinsic apoptotic signaling pathway	05010
1419549_at	Arg1	arginase, liver	10	-24915206	NM_007482	11846	276	urea cycle positive regulation of endothelial cell proliferation adaptive immune response immune system process arginase activity arginase activity arginase activity extracellular space cytoplasm cytoplasm mitochondrial outer membrane cytosol arginine metabolic process hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines arginine catabolic process to ornithine arginine catabolic process to ornithine manganese ion binding manganese ion binding collagen biosynthetic process negative regulation of T cell proliferation identical protein binding defense response to protozoan neuronal cell body innate immune response negative regulation of activated T cell proliferation metal ion binding negative regulation of type II interferon-mediated signaling pathway positive regulation of neutrophil mediated killing of fungus regulation of L-arginine import across plasma membrane negative regulation of T-helper 2 cell cytokine production	00330 01100 05146
1418847_at	Arg2	arginase type II	12	79130787	NM_009705	11847	119	urea cycle ureteric bud development adaptive immune response immune system process negative regulation of type 2 immune response arginase activity arginase activity cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion arginine metabolic process striated muscle contraction hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines arginine catabolic process to ornithine arginine catabolic process to ornithine manganese ion binding regulation of interleukin-1 beta production negative regulation of interleukin-13 production negative regulation of interleukin-17 production negative regulation of tumor necrosis factor production negative regulation of tumor necrosis factor production innate immune response negative regulation of striated muscle contraction metal ion binding nitric-oxide synthase binding negative regulation of macrophage inflammatory protein 1 alpha production negative regulation of chemokine (C-C motif) ligand 4 production negative regulation of chemokine (C-C motif) ligand 5 production negative regulation of defense response to bacterium regulation of reactive oxygen species biosynthetic process negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process regulation of L-arginine import across plasma membrane negative regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of cellular senescence	00330 01100 05146
1448605_at	Rhoc	ras homolog family member C	3	104789033	NM_007484	11853	46	nucleotide binding mitotic cytokinesis mitotic cytokinesis GTPase activity GTPase activity protein binding GTP binding GTP binding nucleus cytosol cytosol plasma membrane plasma membrane plasma membrane actin filament organization signal transduction small GTPase-mediated signal transduction membrane protein kinase binding positive regulation of cell migration positive regulation of protein-containing complex assembly cleavage furrow stereocilium regulation of actin cytoskeleton organization apical junction assembly apical junction assembly positive regulation of stress fiber assembly positive regulation of lipase activity
1450897_at	Arhgap5	Rho GTPase activating protein 5	12	52516076	BM248774	11855	40	positive regulation of mesenchymal cell proliferation GTPase activity GTPase activator activity GTPase activator activity GTP binding cytoplasm endoplasmic reticulum cytosol cytosol plasma membrane signal transduction Rho protein signal transduction regulation of cell size regulation of cell size epithelial cell migration positive regulation of epithelial cell migration membrane cell migration mammary gland development SH2 domain binding	04510 04670
1416735_at	Asah1	N-acylsphingosine amidohydrolase 1	8	-41340645	NM_019734	11886	64	transcription corepressor activity extracellular region extracellular space nucleus nucleus lysosome lipid metabolic process fatty acid metabolic process sphingolipid metabolic process response to organic substance hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides nuclear receptor binding N-acylsphingosine amidohydrolase activity N-acylsphingosine amidohydrolase activity N-acylsphingosine amidohydrolase activity fatty acid amide hydrolase activity keratinocyte differentiation lung development sphingosine biosynthetic process sphingosine biosynthetic process ceramide biosynthetic process ceramide catabolic process ceramide catabolic process ceramide catabolic process regulation of steroid biosynthetic process regulation of programmed necrotic cell death cellular response to tumor necrosis factor ceramidase activity	00600 01100 04142
1429123_at	Rab27a	RAB27A, member RAS oncogene family	9	73064147, 73044809	BB025283	11891	157	nucleotide binding photoreceptor outer segment GTPase activity GTPase activity G protein activity protein binding GTP binding GTP binding GTP binding intracellular anatomical structure lysosome endosome late endosome Golgi apparatus Golgi apparatus exocytosis exocytosis blood coagulation protein secretion positive regulation of gene expression membrane vesicle-mediated transport apical plasma membrane apical plasma membrane hydrolase activity GDP binding antigen processing and presentation protein domain specific binding secretory granule secretory granule secretory granule melanocyte differentiation dendrite myosin V binding melanosome localization melanosome transport multivesicular body membrane Weibel-Palade body multivesicular body organization melanosome melanosome melanosome cytotoxic T cell degranulation natural killer cell degranulation pigmentation positive regulation of exocytosis positive regulation of exocytosis positive regulation of phagocytosis pigment granule localization pigment granule transport exocytic vesicle exocytic vesicle multivesicular body sorting pathway complement-dependent cytotoxicity positive regulation of regulated secretory pathway positive regulation of reactive oxygen species biosynthetic process positive regulation of constitutive secretory pathway exosomal secretion
1421205_at	Atm	ataxia telangiectasia mutated	9	-53437121	NM_007499	11920	660	DNA damage checkpoint signaling DNA damage checkpoint signaling DNA damage checkpoint signaling nucleotide binding pexophagy telomere maintenance double-strand break repair via homologous recombination chromosome, telomeric region ovarian follicle development response to hypoxia somitogenesis pre-B cell allelic exclusion immune system process immunoglobulin production DNA binding protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity DNA-dependent protein kinase activity protein binding ATP binding nucleus nucleus nucleus nucleus nucleoplasm nucleoplasm nucleolus cytoplasm peroxisome peroxisomal matrix centrosome spindle cytoskeleton DNA repair DNA repair protein phosphorylation protein phosphorylation protein phosphorylation DNA damage response DNA damage response DNA damage response cell cycle mitotic spindle assembly checkpoint signaling mitotic G2 DNA damage checkpoint signaling male meiotic nuclear division female meiotic nuclear division female gamete generation brain development heart development determination of adult lifespan female gonad development intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage post-embryonic development response to ionizing radiation response to ionizing radiation regulation of autophagy regulation of autophagy positive regulation of gene expression kinase activity 1-phosphatidylinositol-3-kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation positive regulation of cell migration negative regulation of B cell proliferation cytoplasmic vesicle regulation of telomere maintenance via telomerase positive regulation of telomere maintenance via telomerase V(D)J recombination cellular response to reactive oxygen species multicellular organism growth histone H2AXS139 kinase activity peptidyl-serine autophosphorylation lipoprotein catabolic process signal transduction in response to DNA damage identical protein binding positive regulation of apoptotic process intracellular membrane-bounded organelle positive regulation of DNA damage response, signal transduction by p53 class mediator positive regulation of neuron apoptotic process positive regulation of neuron apoptotic process protein-containing complex binding meiotic telomere clustering positive regulation of cell adhesion positive regulation of transcription by RNA polymerase II protein autophosphorylation thymus development oocyte development neuron apoptotic process regulation of cell cycle chromosome organization involved in meiotic cell cycle histone mRNA catabolic process cellular response to retinoic acid cellular response to ionizing radiation cellular response to gamma radiation cellular response to X-ray cellular response to nitrosative stress replicative senescence establishment of RNA localization to telomere establishment of protein-containing complex localization to telomere positive regulation of DNA catabolic process regulation of microglial cell activation negative regulation of TORC1 signaling negative regulation of TORC1 signaling negative regulation of TORC1 signaling negative regulation of telomere capping positive regulation of telomere maintenance via telomere lengthening positive regulation of telomerase catalytic core complex assembly DNA repair complex	04110 04115 04210
1439036_a_at	Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	1	-164437098	AV152334	11931	93	response to hypoxia ATPase activator activity ATPase activator activity ATPase activator activity blastocyst development P-type sodium:potassium-exchanging transporter activity protein binding plasma membrane plasma membrane sodium:potassium-exchanging ATPase complex sodium:potassium-exchanging ATPase complex sodium:potassium-exchanging ATPase complex caveola monoatomic ion transport potassium ion transport sodium ion transport intracellular calcium ion homeostasis intracellular sodium ion homeostasis intracellular sodium ion homeostasis cell adhesion establishment or maintenance of transmembrane electrochemical gradient regulation of gene expression regulation of cardiac muscle contraction by calcium ion signaling intercalated disc membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane apical plasma membrane lateral plasma membrane protein kinase binding metal ion transport intracellular potassium ion homeostasis intracellular potassium ion homeostasis T-tubule protein-macromolecule adaptor activity organelle membrane positive regulation of ATP-dependent activity sodium ion transmembrane transport sperm flagellum sodium ion export across plasma membrane sodium ion export across plasma membrane sodium ion export across plasma membrane sarcolemma myelin sheath ATP metabolic process protein heterodimerization activity protein stabilization protein stabilization ATPase binding relaxation of cardiac muscle cardiac muscle contraction protein localization to plasma membrane membrane repolarization monoatomic cation transmembrane transport positive regulation of potassium ion transmembrane transporter activity proton transmembrane transport regulation of calcium ion transmembrane transport positive regulation of sodium ion export across plasma membrane positive regulation of calcium:sodium antiporter activity positive regulation of potassium ion import across plasma membrane positive regulation of P-type sodium:potassium-exchanging transporter activity positive regulation of P-type sodium:potassium-exchanging transporter activity potassium ion import across plasma membrane potassium ion import across plasma membrane	04260 04960 04964 04970 04971 04972 04973 04974 04976
1423126_at	Atp1b3	ATPase, Na+/K+ transporting, beta 3 polypeptide	9	-96332655, -96332655	BI080505	11933	32	ATPase activator activity ATPase activator activity P-type sodium:potassium-exchanging transporter activity protein binding cytoplasm plasma membrane sodium:potassium-exchanging ATPase complex sodium:potassium-exchanging ATPase complex caveola monoatomic ion transport potassium ion transport sodium ion transport intracellular sodium ion homeostasis intracellular sodium ion homeostasis membrane basolateral plasma membrane apical plasma membrane metal ion transport intracellular potassium ion homeostasis intracellular potassium ion homeostasis protein-macromolecule adaptor activity positive regulation of ATP-dependent activity sodium ion transmembrane transport sperm flagellum sodium ion export across plasma membrane sodium ion export across plasma membrane protein stabilization ATPase binding potassium ion transmembrane transport protein localization to plasma membrane membrane repolarization positive regulation of potassium ion transmembrane transporter activity positive regulation of sodium ion export across plasma membrane positive regulation of potassium ion import across plasma membrane potassium ion import across plasma membrane potassium ion import across plasma membrane	04260 04960 04964 04970 04971 04972 04973 04974 04976
1438809_at	Atp5f1c	ATP synthase F1 subunit gamma	2	-10056030, -10056030	AI644507	11949	53	mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) protein binding mitochondrion mitochondrial inner membrane mitochondrial inner membrane mitochondrial proton-transporting ATP synthase complex ATP biosynthetic process monoatomic ion transport proton motive force-driven ATP synthesis proton motive force-driven ATP synthesis membrane ATP hydrolysis activity proton motive force-driven mitochondrial ATP synthesis myelin sheath proton-transporting ATP synthase complex, catalytic core F(1) proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATP synthase activity, rotational mechanism proton transmembrane transport	00190 01100 05010 05012 05016
1422508_at	Atp6v1a	ATPase, H+ transporting, lysosomal V1 subunit A	16	-44085403	NM_007508	11964	50	nucleotide binding vacuolar proton-transporting V-type ATPase, V1 domain ATP binding nucleoplasm cytoplasm mitochondrion lysosome cytosol cytosol plasma membrane microvillus monoatomic ion transport intracellular iron ion homeostasis membrane apical plasma membrane ATP hydrolysis activity secretory granule cytoplasmic vesicle proton-transporting V-type ATPase complex proton-transporting V-type ATPase, V1 domain cellular response to increased oxygen levels myelin sheath intracellular membrane-bounded organelle ATP metabolic process proton-transporting ATP synthase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism proton-transporting ATPase activity, rotational mechanism synaptic vesicle lumen acidification synaptic vesicle lumen acidification synaptic vesicle lumen acidification extrinsic component of synaptic vesicle membrane transmembrane transporter complex proton transmembrane transport proton transmembrane transport ATPase complex	00190 01100 04145 04966 05323
1436515_at	Bach2	BTB and CNC homology, basic leucine zipper transcription factor 2	4	32417434	BB529913	12014	101	negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm cytoplasm cytosol regulation of DNA-templated transcription regulation of transcription by RNA polymerase II ion binding import into nucleus RNA polymerase II transcription regulator complex primary adaptive immune response involving T cells and B cells sequence-specific double-stranded DNA binding
1440770_at	Bcl2	B cell leukemia/lymphoma 2	1	-106538175, -106712164	AI505544	12043	792	G1/S transition of mitotic cell cycle protein polyubiquitination mitotic cell cycle cell morphogenesis cell morphogenesis response to acid chemical ossification ovarian follicle development metanephros development ureteric bud development branching involved in ureteric bud morphogenesis branching involved in ureteric bud morphogenesis behavioral fear response leukocyte homeostasis B cell homeostasis B cell apoptotic process B cell apoptotic process kidney development kidney development release of cytochrome c from mitochondria regulation of cell-matrix adhesion protease binding lymphocyte homeostasis lymphocyte homeostasis lymphoid progenitor cell differentiation B cell lineage commitment T cell lineage commitment immune system development negative regulation of B cell apoptotic process response to ischemia renal system process protein binding intracellular anatomical structure nucleus nucleus cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane cytosol protein dephosphorylation melanin metabolic process regulation of nitrogen utilization intracellular calcium ion homeostasis apoptotic process apoptotic process DNA damage response response to oxidative stress actin filament organization axonogenesis transcription factor binding cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation male gonad development extrinsic apoptotic signaling pathway via death domain receptors intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to oxidative stress apoptotic mitochondrial changes response to xenobiotic stimulus response to xenobiotic stimulus response to toxic substance response to toxic substance post-embryonic development post-embryonic development post-embryonic development animal organ morphogenesis response to iron ion response to UV-B response to gamma radiation regulation of gene expression regulation of autophagy negative regulation of autophagy negative regulation of autophagy negative regulation of calcium ion transport into cytosol regulation of glycoprotein biosynthetic process negative regulation of cardiac muscle cell apoptotic process mesenchymal cell development positive regulation of neuron maturation smooth muscle cell migration positive regulation of smooth muscle cell migration channel activity membrane membrane cell growth channel inhibitor activity cell migration peptidyl-serine phosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation protein phosphatase binding cochlear nucleus development gland morphogenesis regulation of transmembrane transporter activity mitochondrial crista hemopoiesis B cell differentiation T cell differentiation T cell differentiation negative regulation of ossification positive regulation of cell growth negative regulation of cell growth melanocyte differentiation melanocyte differentiation negative regulation of cell migration positive regulation of B cell proliferation hair follicle morphogenesis axon regeneration ubiquitin protein ligase binding regulation of protein stability nuclear membrane nuclear membrane mitochondrial membrane endoplasmic reticulum calcium ion homeostasis glomerulus development negative regulation of cellular pH reduction regulation of protein localization protein-containing complex myeloid cell apoptotic process negative regulation of myeloid cell apoptotic process T cell differentiation in thymus positive regulation of peptidyl-serine phosphorylation osteoblast proliferation negative regulation of osteoblast proliferation response to cytokine response to cytokine response to nicotine organ growth regulation of growth positive regulation of multicellular organism growth B cell proliferation cellular response to glucose starvation response to hydrogen peroxide neuron maturation identical protein binding protein homodimerization activity regulation of apoptotic process T cell homeostasis T cell homeostasis negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process regulation of programmed cell death positive regulation of catalytic activity myelin sheath CD8-positive, alpha-beta T cell lineage commitment pigmentation negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process ear development ear development protein-containing complex binding regulation of viral genome replication response to ethanol positive regulation of melanocyte differentiation negative regulation of mitotic cell cycle retinal cell programmed cell death negative regulation of retinal cell programmed cell death regulation of mitochondrial membrane permeability pore complex protein heterodimerization activity protein heterodimerization activity focal adhesion assembly developmental pigmentation developmental pigmentation developmental pigmentation regulation of developmental pigmentation positive regulation of developmental pigmentation positive regulation of developmental pigmentation perinuclear region of cytoplasm spleen development spleen development thymus development thymus development response to steroid hormone digestive tract morphogenesis developmental growth oocyte development skeletal muscle fiber development positive regulation of skeletal muscle fiber development pigment granule organization stem cell development homeostasis of number of cells within a tissue regulation of catalytic activity B cell receptor signaling pathway response to glucocorticoid response to glucocorticoid BH domain binding neuron apoptotic process neuron apoptotic process neuron apoptotic process BH3 domain binding defense response to virus establishment of localization in cell protein phosphatase 2A binding regulation of cell cycle regulation of mitochondrial membrane potential regulation of calcium ion transport molecular adaptor activity hematopoietic stem cell differentiation calcium ion transport into cytosol intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress lymphocyte apoptotic process negative regulation of lymphocyte apoptotic process T cell apoptotic process T cell apoptotic process negative regulation of T cell apoptotic process cellular response to organic substance cellular response to hypoxia reactive oxygen species metabolic process dendritic cell apoptotic process motor neuron apoptotic process BAD-BCL-2 complex extrinsic apoptotic signaling pathway in absence of ligand extrinsic apoptotic signaling pathway in absence of ligand cell-cell adhesion DNA-binding transcription factor binding epithelial cell apoptotic process negative regulation of epithelial cell apoptotic process negative regulation of G1/S transition of mitotic cell cycle negative regulation of G1/S transition of mitotic cell cycle negative regulation of reactive oxygen species metabolic process negative regulation of dendritic cell apoptotic process negative regulation of motor neuron apoptotic process negative regulation of anoikis negative regulation of apoptotic signaling pathway negative regulation of apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand negative regulation of intrinsic apoptotic signaling pathway negative regulation of intrinsic apoptotic signaling pathway	04141 04210 04510 04722 05014 05145 05200 05210 05215 05222
1418133_at	Bcl3	B cell leukemia/lymphoma 3	7	-19808461	NM_033601	12051	93	follicular dendritic cell differentiation marginal zone B cell differentiation humoral immune response mediated by circulating immunoglobulin germinal center formation transcription coactivator activity transcription corepressor activity protein binding nucleus nucleus nucleoplasm cytoplasm cytosol plasma membrane protein import into nucleus DNA damage response canonical NF-kappaB signal transduction response to virus response to UV-C antimicrobial humoral response extracellular matrix organization DNA damage response, signal transduction by p53 class mediator midbody protein-macromolecule adaptor activity negative regulation of NF-kappaB transcription factor activity type II interferon production negative regulation of interleukin-8 production negative regulation of tumor necrosis factor production positive regulation of type II interferon production positive regulation of interleukin-10 production protein-containing complex Bcl3-Bcl10 complex Bcl3/NF-kappaB2 complex Bcl3/NF-kappaB2 complex T-helper 1 type immune response defense response to bacterium intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator histone deacetylase binding histone deacetylase binding defense response to protozoan regulation of apoptotic process regulation of apoptotic process negative regulation of apoptotic process intracellular membrane-bounded organelle T-helper 2 cell differentiation positive regulation of translation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of receptor signaling pathway via JAK-STAT spleen development T cell apoptotic process T cell apoptotic process negative regulation of T cell apoptotic process negative regulation of T cell apoptotic process DNA-binding transcription factor binding DNA-binding transcription factor binding
1450624_at	Bhmt	betaine-homocysteine methyltransferase	13	-93616890	NM_016668	12116	46	nucleus cytosol cytosol amino-acid betaine metabolic process methyltransferase activity zinc ion binding methionine biosynthetic process methionine biosynthetic process protein-containing complex identical protein binding protein-containing complex binding betaine-homocysteine S-methyltransferase activity betaine-homocysteine S-methyltransferase activity betaine-homocysteine S-methyltransferase activity extracellular exosome 'de novo' L-methionine biosynthetic process L-methionine salvage L-methionine salvage	00260 00270 01100
1450779_at	Fabp7	fatty acid binding protein 7, brain	10	57784922	NM_021272	12140	376	startle response fatty acid binding fatty acid binding nucleus cytoplasm cytosol cytosol cell-cell junction lipid binding fatty acid transport cell proliferation in forebrain neurogenesis cell projection neuronal cell body epithelial cell proliferation prepulse inhibition cell periphery	03320
1422775_at	Blk	B lymphoid kinase	14	-63372836	NM_007549	12143	44	nucleotide binding protein kinase activity protein tyrosine kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity signaling receptor binding protein binding ATP binding cytosol plasma membrane protein phosphorylation protein phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway membrane kinase activity phosphorylation transferase activity peptidyl-tyrosine phosphorylation cell differentiation positive regulation of insulin secretion positive regulation of protein binding innate immune response B cell receptor signaling pathway
1422003_at	Cxcr5	C-X-C motif chemokine receptor 5	9	-44511786	NM_007551	12145	159	G protein-coupled receptor activity plasma membrane chemotaxis immune response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration external side of plasma membrane external side of plasma membrane membrane C-C chemokine receptor activity C-X-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding leukocyte chemotaxis positive regulation of cytokinesis B cell activation lymph node development cell chemotaxis	04060 04062
1448733_at	Bmi1	Bmi1 polycomb ring finger oncogene	2	18677017	M64279	12151	354	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II ubiquitin ligase complex heterochromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding skeletal system development in utero embryonic development chromatin binding protein binding nucleus cytoplasm cytosol DNA methylation chromatin organization chromatin organization humoral immune response brain development zinc ion binding nuclear body nuclear body rostrocaudal neural tube patterning positive regulation of B cell proliferation PcG protein complex PcG protein complex positive regulation of immature T cell proliferation in thymus PRC1 complex PRC1 complex PRC1 complex sequence-specific DNA binding metal ion binding somatic stem cell division embryonic skeletal system morphogenesis embryonic skeletal system development hematopoietic stem cell homeostasis RING-like zinc finger domain binding ubiquitin-protein transferase activator activity apoptotic signaling pathway promoter-specific chromatin binding promoter-specific chromatin binding promoter-specific chromatin binding regulation of adaxial/abaxial pattern formation negative regulation of apoptotic signaling pathway
1422084_at	Bmx	BMX non-receptor tyrosine kinase	X	-164192841	AF012104	12169	37	nucleotide binding adaptive immune response protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity ATP binding nucleoplasm cytoplasm plasma membrane plasma membrane protein phosphorylation protein phosphorylation apoptotic process cell adhesion signal transduction kinase activity phosphorylation transferase activity ruffle membrane intracellular signal transduction protein autophosphorylation metal ion binding B cell receptor signaling pathway
1449453_at	Bst1	bone marrow stromal cell antigen 1	5	43818892	AI647987	12182	39	uropod regulation of cell-matrix adhesion NAD+ nucleosidase activity NAD+ nucleosidase activity plasma membrane plasma membrane positive regulation of cell population proliferation membrane transferase activity hydrolase activity phosphorus-oxygen lyase activity positive regulation of B cell proliferation regulation of actin cytoskeleton organization NADP+ nucleosidase activity regulation of inflammatory response regulation of peptidyl-tyrosine phosphorylation regulation of calcium-mediated signaling NAD+ nucleotidase, cyclic ADP-ribose generating regulation of neutrophil chemotaxis side of membrane	00760 01100 04020 04970 04972
1450644_at	Zfp36l1	zinc finger protein 36, C3H type-like 1	12	-80107759	M58566	12192	57	MAPK cascade MAPK cascade MAPK cascade nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay P-body vasculogenesis proepicardium development DNA binding RNA binding mRNA binding mRNA binding protein binding nucleus nucleus cytoplasm cytoplasm cytosol mRNA processing mRNA catabolic process regulation of translation apoptotic process multicellular organism development heart development cell population proliferation response to wounding regulation of gene expression regulation of keratinocyte proliferation neural tube development nuclear-transcribed mRNA catabolic process, deadenylation-independent decay regulation of mRNA 3'-end processing cellular response to insulin stimulus T cell differentiation in thymus T cell differentiation in thymus multicellular organism growth mRNA 3'-UTR AU-rich region binding mRNA 3'-UTR AU-rich region binding mRNA 3'-UTR AU-rich region binding p38MAPK cascade regulation of mRNA stability regulation of mRNA stability regulation of mRNA stability phosphatidylinositol 3-kinase/protein kinase B signal transduction phosphatidylinositol 3-kinase/protein kinase B signal transduction cellular response to fibroblast growth factor stimulus regulation of B cell differentiation positive regulation of fat cell differentiation regulation of keratinocyte differentiation negative regulation of erythrocyte differentiation positive regulation of monocyte differentiation regulation of myoblast differentiation metal ion binding mesendoderm development embryonic organ development mRNA transport chorio-allantoic fusion spongiotrophoblast layer development 3'-UTR-mediated mRNA destabilization 3'-UTR-mediated mRNA destabilization 3'-UTR-mediated mRNA destabilization ERK1 and ERK2 cascade cellular response to cAMP cellular response to cAMP cellular response to tumor necrosis factor cellular response to epidermal growth factor stimulus cellular response to peptide hormone stimulus cellular response to peptide hormone stimulus cellular response to glucocorticoid stimulus cellular response to hypoxia cellular response to salt stress cellular response to transforming growth factor beta stimulus 14-3-3 protein binding regulation of stem cell proliferation cellular response to raffinose positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay negative regulation of mitotic cell cycle phase transition regulation of keratinocyte apoptotic process positive regulation of intracellular mRNA localization ribonucleoprotein complex ribonucleoprotein complex ribonucleoprotein complex
1451021_a_at	Klf5	Kruppel-like transcription factor 5	14	99298690	BI465857	12224	179	negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific angiogenesis DNA binding DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm nucleoplasm transcription regulator complex Golgi apparatus regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of gene expression skeletal muscle satellite cell differentiation satellite cell activation involved in skeletal muscle regeneration myotube differentiation involved in skeletal muscle regeneration myotube differentiation involved in skeletal muscle regeneration microvillus assembly regulation of microvillus assembly skeletal muscle cell differentiation intracellular membrane-bounded organelle skeletal muscle tissue regeneration MRF binding sequence-specific DNA binding positive regulation of fat cell differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding intestinal epithelial cell development positive regulation of transcription by transcription factor localization cell-cell signaling via exosome positive regulation of miRNA transcription cellular response to leukemia inhibitory factor sequence-specific double-stranded DNA binding
1442018_at	Btg1	BTG anti-proliferation factor 1	10	96617000	BE632903	12226	50	nucleus nucleus cytoplasm cytoplasm protein methylation cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation enzyme binding positive regulation of catalytic activity positive regulation of endothelial cell differentiation positive regulation of myoblast differentiation positive regulation of angiogenesis negative regulation of mitotic cell cycle positive regulation of fibroblast apoptotic process	03018
1438948_x_at	Tspo	translocator protein	15	83563572	AV101079	12257	142	androgen binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane endoplasmic reticulum cytosol steroid biosynthetic process monoatomic ion transport chloride transport lipid transport glial cell migration benzodiazepine receptor activity negative regulation of mitochondrion organization cholesterol binding membrane negative regulation of protein ubiquitination negative regulation of tumor necrosis factor production cholesterol homeostasis positive regulation of apoptotic process intracellular membrane-bounded organelle transmembrane transporter binding negative regulation of nitric oxide biosynthetic process behavioral response to pain regulation of steroid biosynthetic process positive regulation of mitochondrial depolarization positive regulation of calcium ion transport contact inhibition positive regulation of glial cell proliferation negative regulation of glial cell proliferation positive regulation of programmed necrotic cell death establishment of protein localization to mitochondrion maintenance of protein location in mitochondrion negative regulation of mitophagy negative regulation of ATP metabolic process response to acetylcholine positive regulation of reactive oxygen species metabolic process positive regulation of reactive oxygen species metabolic process negative regulation of corticosterone secretion	04080
1416625_at	Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	2	-84765359	NM_009776	12258	43	complement binding negative regulation of complement activation, lectin pathway immune system process serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity extracellular region extracellular space extracellular space extracellular space extracellular space complement activation, classical pathway blood coagulation hemostasis negative regulation of peptidase activity negative regulation of endopeptidase activity peptidase inhibitor activity fibrinolysis innate immune response collagen-containing extracellular matrix	04610
1449401_at	C1qc	complement component 1, q subcomponent, C chain	4	-136889801	NM_007574	12262	34	immune system process extracellular region extracellular region collagen trimer complement component C1 complex extracellular space complement activation, classical pathway complement activation, classical pathway negative regulation of granulocyte differentiation innate immune response synapse synapse synapse negative regulation of macrophage differentiation complement component C1q complex postsynapse synapse pruning	04610 05020 05142 05150 05322
1421211_a_at	Ciita	class II transactivator	16	10480071, 10489780, 10488177	AF042158	12265	187	negative regulation of transcription by RNA polymerase II nucleotide binding transcription cis-regulatory region binding protein serine/threonine kinase activity protein binding ATP binding GTP binding nucleus nucleoplasm cytosol regulation of DNA-templated transcription cell surface kinase activity phosphorylation PML body transferase activity acyltransferase activity response to type II interferon response to type II interferon protein-containing complex binding positive regulation of MHC class I biosynthetic process positive regulation of MHC class I biosynthetic process positive regulation of MHC class II biosynthetic process positive regulation of MHC class II biosynthetic process negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of viral entry into host cell response to antibiotic DNA-binding transcription factor binding	04612 05145 05340
1423954_at	C3	complement component 3	17	-57203966	K02782	12266	681	positive regulation of type IIa hypersensitivity positive regulation of protein phosphorylation positive regulation of activation of membrane attack complex immune system process complement receptor mediated signaling pathway endopeptidase inhibitor activity protein binding extracellular region extracellular space extracellular space extracellular space extracellular space lipid metabolic process fatty acid metabolic process inflammatory response complement activation complement activation complement activation complement activation complement activation, alternative pathway complement activation, classical pathway lipid binding response to bacterium cell surface positive regulation of vascular endothelial growth factor production positive regulation of glucose transmembrane transport regulation of triglyceride biosynthetic process positive regulation of lipid storage neuron remodeling C5L2 anaphylatoxin chemotactic receptor binding protein-containing complex oviduct epithelium development vascular associated smooth muscle cell differentiation innate immune response positive regulation of G protein-coupled receptor signaling pathway positive regulation of angiogenesis positive regulation of receptor-mediated endocytosis positive regulation of receptor-mediated endocytosis positive regulation of developmental growth positive regulation of phagocytosis retina development in camera-type eye positive regulation of phagocytosis, engulfment positive regulation of phagocytosis, engulfment positive regulation of ERK1 and ERK2 cascade amyloid-beta clearance amyloid-beta clearance complement-dependent cytotoxicity complement-mediated synapse pruning vertebrate eye-specific patterning positive regulation of apoptotic cell clearance	04145 04610 05140 05142 05150 05322
1439902_at	C5ar1	complement component 5a receptor 1	7	-16246742, -16246744	BB552085	12273	290	microglial cell activation complement component C5a binding complement receptor mediated signaling pathway complement receptor activity complement component C5a receptor activity complement component C5a receptor activity complement component C5a receptor activity G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane chemotaxis inflammatory response signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration cell surface positive regulation of vascular endothelial growth factor production positive regulation of macrophage chemotaxis membrane basolateral plasma membrane cell proliferation in hindbrain neutrophil chemotaxis cytoplasmic vesicle response to peptidoglycan complement component C5a signaling pathway mRNA transcription by RNA polymerase II negative regulation of neuron apoptotic process apical part of cell positive regulation of angiogenesis astrocyte activation positive regulation of epithelial cell proliferation defense response to Gram-positive bacterium cognition positive regulation of ERK1 and ERK2 cascade positive regulation of neutrophil chemotaxis amyloid-beta clearance presynapse organization regulation of tau-protein kinase activity	04080 04610 05150
1419091_a_at	Anxa2	annexin A2	9	69453682	NM_007585	12306	171	angiogenesis cornified envelope stress fiber ruffle phosphatidylserine binding positive regulation of receptor recycling positive regulation of protein phosphorylation protease binding phospholipase inhibitor activity serine-type endopeptidase inhibitor activity calcium ion binding protein binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding phosphatidylinositol-4,5-bisphosphate binding extracellular region basement membrane extracellular space cytoplasm cytoplasm cytoplasm lysosomal membrane endosome early endosome lipid droplet cytosol cytosol cytosol plasma membrane plasma membrane plasma membrane cell cortex cell adhesion cell-matrix adhesion body fluid secretion cytoskeletal protein binding cell surface cell surface response to activity membrane membrane basolateral plasma membrane nuclear matrix phospholipase A2 inhibitor activity cell junction collagen fibril organization lung development midbody small GTPase binding late endosome membrane vesicle negative regulation of low-density lipoprotein particle receptor catabolic process protein-containing complex myelin sheath adaxonal region sarcolemma fibrinolysis mRNA transcription by RNA polymerase II identical protein binding Schmidt-Lanterman incisure macropinosome S100 protein binding bone sialoprotein binding membrane raft positive regulation of exocytosis positive regulation of transcription by RNA polymerase II positive regulation of fibroblast proliferation calcium-dependent protein binding perinuclear region of cytoplasm regulation of neurogenesis positive regulation of binding collagen-containing extracellular matrix extracellular exosome cellular response to acid chemical protein localization to plasma membrane RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex plasma membrane protein complex plasma membrane protein complex plasma membrane protein complex epithelial cell apoptotic process positive regulation of low-density lipoprotein particle clearance positive regulation of low-density lipoprotein particle receptor binding positive regulation of low-density lipoprotein receptor activity positive regulation of receptor-mediated endocytosis involved in cholesterol transport positive regulation of receptor-mediated endocytosis involved in cholesterol transport positive regulation of plasma membrane repair AnxA2-p11 complex PCSK9-AnxA2 complex
1423097_s_at	Capn7	calpain 7	14	31336637	BQ257745	12339	23	endopeptidase activity cysteine-type endopeptidase activity calcium-dependent cysteine-type endopeptidase activity nucleus centrosome cytosol proteolysis proteolysis peptidase activity cysteine-type peptidase activity positive regulation of epithelial cell migration hydrolase activity MIT domain binding self proteolysis
1449434_at	Car3	carbonic anhydrase 3	3	14863537	NM_007606	12350	68	carbonate dehydratase activity carbonate dehydratase activity cytoplasm cytoplasm cytosol cytosol cytosol one-carbon metabolic process response to oxidative stress zinc ion binding response to bacterium nickel cation binding phosphatase activity lyase activity metal ion binding	00910
1448949_at	Car4	carbonic anhydrase 4	11	84957753	NM_007607	12351	66	carbonate dehydratase activity carbonate dehydratase activity carbonate dehydratase activity protein binding rough endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment Golgi apparatus trans-Golgi network plasma membrane plasma membrane plasma membrane one-carbon metabolic process regulation of pH zinc ion binding external side of plasma membrane cell surface carbon dioxide transport bicarbonate transport membrane apical plasma membrane sarcoplasmic reticulum lyase activity transport vesicle membrane secretory granule membrane brush border membrane sarcolemma metal ion binding perinuclear region of cytoplasm extracellular exosome side of membrane	00910
1449265_at	Casp1	caspase 1	9	5298516	BC008152	12362	965	response to hypoxia response to hypoxia microglial cell activation positive regulation of cytokine production positive regulation of cytokine production pattern recognition receptor signaling pathway endopeptidase activity cysteine-type endopeptidase activity cysteine-type endopeptidase activity protein binding extracellular region cytoplasm cytoplasm cytoplasm cytoplasm cytosol cytosol cytosol microtubule plasma membrane proteolysis apoptotic process osmosensory signaling pathway myoblast fusion memory peptidase activity cysteine-type peptidase activity response to xenobiotic stimulus response to bacterium regulation of autophagy macrophage cytokine production response to organic cyclic compound membrane protein processing protein processing protein autoprocessing protein autoprocessing hydrolase activity kinase binding response to lipopolysaccharide response to lipopolysaccharide interleukin-1 alpha production interleukin-1 beta production interleukin-1 beta production positive regulation of interleukin-1 alpha production positive regulation of interleukin-1 alpha production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-18 production protein-containing complex response to ATP defense response to bacterium identical protein binding regulation of apoptotic process positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of cysteine-type endopeptidase activity involved in apoptotic process positive regulation of circadian sleep/wake cycle, non-REM sleep CARD domain binding regulation of inflammatory response regulation of inflammatory response regulation of inflammatory response positive regulation of inflammatory response positive regulation of inflammatory response positive regulation of inflammatory response defense response to Gram-negative bacterium protein maturation protein maturation defense response to virus mitochondrial depolarization membrane hyperpolarization positive regulation of macrophage cytokine production canonical inflammasome complex pyroptosis pyroptosis pyroptosis pyroptosis cellular response to lipopolysaccharide cellular response to organic substance cellular response to type II interferon IPAF inflammasome complex IPAF inflammasome complex NLRP1 inflammasome complex NLRP1 inflammasome complex NLRP3 inflammasome complex NLRP3 inflammasome complex caspase binding scaffold protein binding AIM2 inflammasome complex AIM2 inflammasome complex protease inhibitor complex programmed necrotic cell death cytokine precursor processing signaling receptor ligand precursor processing AIM2 inflammasome complex assembly AIM2 inflammasome complex assembly positive regulation of tumor necrosis factor-mediated signaling pathway	04621 04623 05014
1449591_at	Casp4	caspase 4, apoptosis-related cysteine peptidase	9	5308848, 5308859	NM_007609	12363	281	lipopolysaccharide binding lipopolysaccharide binding immune system process cysteine-type endopeptidase activity cysteine-type endopeptidase activity cysteine-type endopeptidase activity cysteine-type endopeptidase activity protein binding extracellular region cytoplasm cytoplasm mitochondrion endoplasmic reticulum cytosol cytosol plasma membrane proteolysis inflammatory response actin filament organization peptidase activity cysteine-type peptidase activity lipid binding macrophage cytokine production programmed cell death membrane protein autoprocessing protein autoprocessing hydrolase activity detection of lipopolysaccharide interleukin-1 beta production positive regulation of interleukin-1 beta production protein-containing complex ectopic germ cell programmed cell death ectopic germ cell programmed cell death defense response to bacterium defense response to bacterium regulation of apoptotic process neuronal cell body positive regulation of neuron apoptotic process innate immune response CARD domain binding regulation of inflammatory response positive regulation of inflammatory response positive regulation of inflammatory response positive regulation of inflammatory response defense response to Gram-positive bacterium protein maturation positive regulation of macrophage cytokine production positive regulation of macrophage cytokine production canonical inflammasome complex pyroptosis pyroptosis NLRP1 inflammasome complex NLRP1 inflammasome complex scaffold protein binding non-canonical inflammasome complex non-canonical inflammasome complex non-canonical inflammasome complex assembly non-canonical inflammasome complex assembly positive regulation of NLRP3 inflammasome complex assembly positive regulation of interleukin-18-mediated signaling pathway
1433718_a_at	Cbx1	chromobox 1	11	96789134, 96789134	BB224832	12412	107	negative regulation of transcription by RNA polymerase II chromosome, centromeric region chromosome, telomeric region chromatin chromatin female pronucleus male pronucleus DNA binding chromatin binding protein binding nucleus nucleus nucleoplasm pericentric heterochromatin pericentric heterochromatin spindle chromatin organization DNA damage response chromocenter nuclear body enzyme binding methylated histone binding identical protein binding intracellular membrane-bounded organelle negative regulation of DNA-templated transcription molecular adaptor activity site of DNA damage histone methyltransferase binding
1419583_at	Cbx4	chromobox 4	11	-119077570	NM_007625	12418	48	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding chromatin binding single-stranded RNA binding protein binding nucleus nucleus nucleoplasm nucleoplasm chromatin organization nuclear body nuclear body transferase activity protein sumoylation protein sumoylation SUMO transferase activity SUMO transferase activity enzyme binding PcG protein complex SUMO binding SUMO binding SUMO binding methylated histone binding PRC1 complex PRC1 complex negative regulation of DNA-templated transcription phosphoprotein binding SUMO ligase activity SUMO ligase activity
1425837_a_at	Noct	nocturnin	3	51224446	AF199491	12457	49	3'-5'-RNA exonuclease activity deadenylation-dependent decapping of nuclear-transcribed mRNA P-body RNA binding mRNA binding catalytic activity poly(A)-specific ribonuclease activity poly(A)-specific ribonuclease activity protein binding nucleus cytoplasm mitochondrion NADP metabolic process circadian rhythm response to extracellular stimulus negative regulation of gene expression hydrolase activity NADP phosphatase activity response to lipopolysaccharide circadian regulation of gene expression P-body assembly regulation of circadian rhythm positive regulation of fat cell differentiation negative regulation of osteoblast differentiation regulation of embryonic development metal ion binding mRNA stabilization perinuclear region of cytoplasm rhythmic process NADPH phosphatase activity
1450357_a_at	Ccr6	C-C motif chemokine receptor 6	17	8243806, 8236042, 8245057, 8242525	NM_009835	12458	182	leukocyte migration involved in inflammatory response G protein-coupled receptor activity chemokine receptor activity protein binding plasma membrane chemotaxis chemotaxis immune response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration external side of plasma membrane external side of plasma membrane cell surface cell surface positive regulation of epithelial cell migration membrane C-C chemokine receptor activity C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling calcium-mediated signaling C-C chemokine binding C-C chemokine binding C-C chemokine binding sperm flagellum sperm flagellum isotype switching to IgA isotypes cell chemotaxis cell chemotaxis positive regulation of flagellated sperm motility involved in capacitation positive regulation of flagellated sperm motility involved in capacitation lymphocyte migration T cell migration thymocyte migration thymocyte migration sperm midpiece sperm principal piece sperm principal piece sperm plasma membrane sperm plasma membrane DN2 thymocyte differentiation DN3 thymocyte differentiation regulation of T cell migration positive regulation of dendritic cell chemotaxis positive regulation of dendritic cell chemotaxis	04060 04062
1417268_at	Cd14	CD14 antigen	18	-36725063	NM_009841	12475	285	lipopolysaccharide binding lipopolysaccharide binding positive regulation of cytokine production positive regulation of cytokine production lipopolysaccharide immune receptor activity response to molecule of bacterial origin immune system process cell surface pattern recognition receptor signaling pathway extracellular region extracellular space Golgi apparatus plasma membrane receptor-mediated endocytosis inflammatory response response to bacterium response to bacterium external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface membrane positive regulation of lipopolysaccharide-mediated signaling pathway positive regulation of type I interferon production positive regulation of type II interferon production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway positive regulation of toll-like receptor 4 signaling pathway response to tumor necrosis factor innate immune response membrane raft membrane raft membrane raft positive regulation of endocytosis lipopolysaccharide receptor complex lipopolysaccharide receptor complex lipoteichoic acid binding cellular response to molecule of bacterial origin cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipoteichoic acid cellular response to diacyl bacterial lipopeptide cellular response to triacyl bacterial lipopeptide side of membrane	04010 04145 04620 04640 04810 05146
1450570_a_at	Cd19	CD19 antigen	7	-126408447	NM_009844	12478	836	B-1 B cell differentiation adaptive immune response B cell proliferation involved in immune response immune system process plasma membrane plasma membrane plasma membrane external side of plasma membrane external side of plasma membrane external side of plasma membrane membrane immunoglobulin mediated immune response B cell mediated immunity protein-containing complex antigen receptor-mediated signaling pathway B cell receptor signaling pathway B cell receptor signaling pathway B cell receptor signaling pathway regulation of B cell receptor signaling pathway regulation of B cell receptor signaling pathway regulation of B cell activation positive regulation of release of sequestered calcium ion into cytosol positive regulation of release of sequestered calcium ion into cytosol positive regulation of release of sequestered calcium ion into cytosol positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	04640 04662 05340
1418770_at	Cd2	CD2 antigen	3	-101275907	NM_013486	12481	72	signaling receptor binding signaling receptor binding protein binding extracellular region nucleoplasm Golgi apparatus plasma membrane plasma membrane cell-cell junction cell adhesion external side of plasma membrane external side of plasma membrane cytoplasmic side of plasma membrane cell surface membrane protein kinase binding natural killer cell activation receptor tyrosine kinase binding positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production protein-containing complex heterotypic cell-cell adhesion natural killer cell mediated cytotoxicity identical protein binding identical protein binding protein self-association cell-cell adhesion cell-cell adhesion	04514 04640
1450912_at	Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	19	-11249678	BB236617	12482	50	store-operated calcium entry epidermal growth factor receptor binding nucleoplasm plasma membrane plasma membrane cell surface receptor signaling pathway response to bacterium external side of plasma membrane external side of plasma membrane cell surface membrane immunoglobulin binding B cell differentiation B cell activation identical protein binding plasma membrane raft B cell receptor signaling pathway protein tetramerization calcium ion import into cytosol positive regulation of calcium ion import across plasma membrane	04640
1419768_at	Cd22	CD22 antigen	7	-30865403, -30865403	AF102134	12483	145	negative regulation of immunoglobulin production protein binding early endosome early endosome plasma membrane cell adhesion cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane cell surface coreceptor activity membrane protein phosphatase binding protein phosphatase binding regulation of endocytosis carbohydrate binding regulation of B cell proliferation regulation of B cell proliferation neuronal cell body membrane sialic acid binding sialic acid binding B cell activation B cell activation CD4 receptor binding CD4 receptor binding regulation of immune response negative regulation of calcium-mediated signaling negative regulation of B cell receptor signaling pathway negative regulation of B cell receptor signaling pathway recycling endosome recycling endosome	04514 04640 04662
1437025_at	Cd28	CD28 antigen	1	60746387	AV313615	12487	529	immunological synapse protease binding positive regulation of inflammatory response to antigenic stimulus plasma membrane transcription by RNA polymerase II immune response external side of plasma membrane external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface positive regulation of gene expression negative regulation of gene expression membrane protein kinase binding T cell costimulation T cell costimulation T cell costimulation T cell costimulation T cell costimulation interleukin-2 production positive regulation of interleukin-10 production positive regulation of interleukin-2 production positive regulation of interleukin-2 production positive regulation of interleukin-4 production CD4-positive, alpha-beta T cell proliferation CD4-positive, alpha-beta T cell proliferation T cell proliferation T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation T cell activation T cell activation regulation of T cell proliferation identical protein binding phosphatidylinositol 3-kinase/protein kinase B signal transduction negative thymic T cell selection regulatory T cell differentiation regulation of regulatory T cell differentiation positive regulation of mitotic nuclear division positive regulation of transcription by RNA polymerase II positive regulation of isotype switching to IgG isotypes T cell receptor signaling pathway T cell receptor signaling pathway positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction apoptotic signaling pathway protein complex involved in cell adhesion positive regulation of CD4-positive, alpha-beta T cell proliferation positive regulation of CD4-positive, alpha-beta T cell proliferation	04514 04660 04672 04940 05320 05322 05323 05330 05332 05416
1450513_at	Cd33	CD33 molecule	7	-43527455	NM_021293	12489	27	nucleoplasm peroxisome Golgi apparatus cytosol plasma membrane plasma membrane cell adhesion cell adhesion external side of plasma membrane cell surface membrane protein phosphatase binding carbohydrate binding sialic acid binding sialic acid binding	04640
1419206_at	Cd37	CD37 antigen	7	-45233631, -45233631	BC019402	12493	35	immunological synapse immunoglobulin production positive regulation of immunoglobulin production regulation of humoral immune response membrane negative regulation of myeloid dendritic cell activation T cell proliferation negative regulation of T cell proliferation defense response to protozoan regulation of defense response to virus	04640
1450136_at	Cd38	CD38 antigen	5	43868808	NM_007646	12494	222	response to hypoxia NAD+ nucleosidase activity NAD+ nucleosidase activity plasma membrane plasma membrane positive regulation of cytosolic calcium ion concentration positive regulation of cell population proliferation response to xenobiotic stimulus response to hormone cell surface negative regulation of neuron projection development artery smooth muscle contraction membrane basolateral plasma membrane transferase activity hydrolase activity hydrolase activity, acting on glycosyl bonds phosphorus-oxygen lyase activity phosphorus-oxygen lyase activity positive regulation of cell growth positive regulation of B cell proliferation positive regulation of B cell proliferation positive regulation of B cell proliferation positive regulation of insulin secretion response to hydroperoxide B cell proliferation identical protein binding negative regulation of apoptotic process negative regulation of bone resorption negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of vasoconstriction NADP+ nucleosidase activity B cell receptor signaling pathway long-term synaptic depression NAD+ nucleotidase, cyclic ADP-ribose generating	00760 01100 04020 04640 04970 04972
1417384_at	Entpd5	ectonucleoside triphosphate diphosphohydrolase 5	12	-84373875, -84373875	NM_007647	12499	30	GDP phosphatase activity GDP phosphatase activity GDP phosphatase activity extracellular region extracellular space endoplasmic reticulum endoplasmic reticulum lumen UDP-glucose metabolic process UDP catabolic process protein N-linked glycosylation nucleoside diphosphate catabolic process membrane hydrolase activity nucleoside diphosphate phosphatase activity ribonucleoside triphosphate phosphatase activity CDP phosphatase activity ADP phosphatase activity UDP phosphatase activity UDP phosphatase activity UDP phosphatase activity 'de novo' post-translational protein folding IDP phosphatase activity	00230 00240
1422828_at	Cd3d	CD3 antigen, delta polypeptide	9	44981785	NM_013487	12500	58	adaptive immune response immune system process transmembrane signaling receptor activity transmembrane signaling receptor activity protein binding plasma membrane cell surface receptor signaling pathway cell surface receptor signaling pathway external side of plasma membrane membrane T cell receptor complex T cell receptor complex alpha-beta T cell receptor complex alpha-beta T cell receptor complex alpha-beta T cell receptor complex T cell activation identical protein binding positive thymic T cell selection positive thymic T cell selection protein-containing complex assembly	04640 04660 05142 05340
1422105_at	Cd3e	CD3 antigen, epsilon polypeptide	9	-44998742	NM_007648	12501	332	immunological synapse positive regulation of cell-matrix adhesion adaptive immune response immune system process positive regulation of T cell anergy T cell anergy transmembrane signaling receptor activity transmembrane signaling receptor activity protein binding endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane cell-cell junction cell surface receptor signaling pathway cell surface receptor signaling pathway smoothened signaling pathway response to nutrient external side of plasma membrane external side of plasma membrane external side of plasma membrane positive regulation of gene expression negative regulation of gene expression membrane dendrite development SH3 domain binding peptidyl-tyrosine phosphorylation calcium-mediated signaling cerebellum development T cell costimulation type II interferon production interleukin-4 production positive regulation of type II interferon production positive regulation of interleukin-2 production positive regulation of interleukin-4 production positive regulation of cell-cell adhesion mediated by integrin CD4-positive, alpha-beta T cell proliferation T cell proliferation T cell receptor complex positive regulation of T cell proliferation positive regulation of T cell proliferation alpha-beta T cell receptor complex alpha-beta T cell receptor complex alpha-beta T cell receptor complex T cell activation identical protein binding dendritic spine cell body positive thymic T cell selection negative thymic T cell selection negative regulation of smoothened signaling pathway lymphocyte activation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling T cell receptor signaling pathway positive regulation of T cell activation apoptotic signaling pathway positive regulation of CD4-positive, alpha-beta T cell proliferation	04640 04660 05142 05340
1419178_at	Cd3g	CD3 antigen, gamma polypeptide	9	-44969571	M58149	12502	65	adaptive immune response immune system process transmembrane signaling receptor activity transmembrane signaling receptor activity cytosol plasma membrane establishment or maintenance of cell polarity cell surface receptor signaling pathway cell surface receptor signaling pathway external side of plasma membrane protein transport membrane alpha-beta T cell receptor complex alpha-beta T cell receptor complex alpha-beta T cell receptor complex identical protein binding positive thymic T cell selection regulation of lymphocyte apoptotic process	04640 04660 05142
1426396_at	Cd247	CD247 antigen	1	165788680, 165788680, 165788680	AK017904	12503	174	adaptive immune response immune system process transmembrane signaling receptor activity protein binding cytoplasm Golgi apparatus plasma membrane plasma membrane cell surface receptor signaling pathway membrane interleukin-2 production Fc-gamma receptor III complex Fc-gamma receptor signaling pathway T cell receptor complex alpha-beta T cell receptor complex alpha-beta T cell receptor complex alpha-beta T cell receptor complex identical protein binding protein homodimerization activity protein heterodimerization activity T cell receptor signaling pathway T cell receptor signaling pathway protein complex oligomerization protein-containing complex assembly protein tyrosine kinase binding positive regulation of protein localization to cell surface	04650 04660 05142
1452483_a_at	Cd44	CD44 antigen	2	-102811141	X66083	12505	648	regulation of cell growth branching involved in ureteric bud morphogenesis wound healing involved in inflammatory response positive regulation of adaptive immune response negative regulation of mature B cell apoptotic process transmembrane signaling receptor activity cytokine receptor activity cytokine receptor activity cytokine receptor activity type II transforming growth factor beta receptor binding epidermal growth factor receptor binding protein binding hyaluronic acid binding hyaluronic acid binding hyaluronic acid binding extracellular region Golgi apparatus cytosol plasma membrane plasma membrane plasma membrane microvillus receptor-mediated endocytosis receptor-mediated endocytosis inflammatory response cell adhesion cell adhesion external side of plasma membrane cell surface cell surface positive regulation of gene expression membrane Wnt signaling pathway channel regulator activity basolateral plasma membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane cell migration protein kinase binding cytokine binding hyaluronan catabolic process hyaluronan catabolic process hyaluronan catabolic process neuron projection development lamellipodium membrane protein-containing complex positive regulation of neutrophil apoptotic process positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation positive regulation of heterotypic cell-cell adhesion macrophage fusion macrophage migration inhibitory factor receptor complex macrophage migration inhibitory factor receptor complex macrophage migration inhibitory factor receptor complex cargo receptor activity cargo receptor activity cargo receptor activity T cell activation cell projection negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of DNA damage response, signal transduction by p53 class mediator wound healing, spreading of cells cellular response to fibroblast growth factor stimulus membrane raft negative regulation of regulatory T cell differentiation negative regulation of inflammatory response positive regulation of peptidyl-tyrosine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation phosphoprotein binding branching involved in prostate gland morphogenesis positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade monocyte aggregation positive regulation of monocyte aggregation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator regulation of lamellipodium morphogenesis negative regulation of CD4-positive, alpha-beta T cell proliferation	04512 04640
1418353_at	Cd5	CD5 antigen	19	-10718142	NM_007650	12507	144	protein binding plasma membrane plasma membrane external side of plasma membrane cell surface membrane T cell costimulation T cell costimulation apoptotic signaling pathway	04640
1451910_a_at	Cd6	CD6 antigen	19	-10789338	U12434	12511	36	lipopolysaccharide binding immunological synapse formation immunological synapse positive regulation of protein phosphorylation acute inflammatory response to antigenic stimulus protein binding plasma membrane cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules cell surface membrane protein kinase binding lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide T cell receptor complex positive regulation of T cell proliferation identical protein binding lipoteichoic acid binding positive regulation of cytokine production involved in inflammatory response	04514
1449164_at	Cd68	CD68 antigen	11	-69664212	BC021637	12514	109	inflammatory response to antigenic stimulus negative regulation of dendritic cell antigen processing and presentation lysosome lysosomal membrane lysosomal membrane endosome plasma membrane plasma membrane plasma membrane membrane cellular response to nutrient levels late endosome membrane autocrine signaling cellular response to lipopolysaccharide cellular response to organic substance establishment of protein localization to organelle cellular response to oxidised low-density lipoprotein particle stimulus	04142
1428735_at	Cd69	CD69 antigen	6	-129267323	AK017979	12515	117	calcium ion binding external side of plasma membrane external side of plasma membrane cell surface membrane carbohydrate binding protein-containing complex identical protein binding cellular response to xenobiotic stimulus
1426112_a_at	Cd72	CD72 antigen	4	-43447723	BC003824	12517	70	transmembrane signaling receptor activity plasma membrane membrane carbohydrate binding	04662
1418830_at	Cd79a	CD79A antigen (immunoglobulin-associated alpha)	7	24897496	NM_007655	12518	432	adaptive immune response immune system process transmembrane signaling receptor activity protein binding multivesicular body plasma membrane plasma membrane cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane membrane B cell receptor complex B cell receptor complex B cell differentiation B cell differentiation B cell proliferation B cell activation identical protein binding membrane raft B cell receptor signaling pathway B cell receptor signaling pathway IgM B cell receptor complex	04662 05340
1416111_at	Cd83	CD83 antigen	13	43785111	NM_009856	12522	66	external side of plasma membrane response to organic cyclic compound membrane interleukin-10 production interleukin-2 production interleukin-4 production negative regulation of interleukin-4 production positive regulation of interleukin-10 production positive regulation of interleukin-2 production CD4-positive, alpha-beta T cell differentiation positive regulation of CD4-positive, alpha-beta T cell differentiation
1451673_at	Cd8a	CD8 subunit alpha	6	71373426	M12825	12525	623	adaptive immune response immune system process T cell mediated immunity T cell mediated immunity protein binding plasma membrane plasma membrane cell surface receptor signaling pathway cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface cell surface membrane calcium-mediated signaling protein kinase binding MHC class I protein complex binding T cell activation identical protein binding receptor complex receptor complex plasma membrane raft cytotoxic T cell differentiation cytotoxic T cell differentiation positive regulation of calcium-mediated signaling T cell receptor signaling pathway defense response to virus	04514 04612 04640 04660 05340
1426170_a_at	Cd8b1	CD8 subunit beta 1	6	71322787	U34882	12526	115	adaptive immune response immune system process protein binding plasma membrane plasma membrane external side of plasma membrane cell surface cell surface coreceptor activity membrane MHC class I protein binding receptor complex regulation of immune response	04514 04612 04640 04660 05340
1426002_a_at	Cdc7	cell division cycle 7	5	106964321, 106964560	AB018574	12545	39	nucleotide binding double-strand break repair via break-induced replication protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm protein phosphorylation cell cycle signal transduction positive regulation of cell population proliferation positive regulation of nuclear cell cycle DNA replication positive regulation of G2/M transition of mitotic cell cycle kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation cell cycle phase transition intercellular bridge metal ion binding cell division mitotic spindle	04110
1424638_at	Cdkn1a	cyclin dependent kinase inhibitor 1A	17	29090978, 29093768	AK007630	12575	1178	regulation of cyclin-dependent protein serine/threonine kinase activity cyclin-dependent protein kinase holoenzyme complex cyclin-dependent protein kinase holoenzyme complex cyclin-dependent protein kinase holoenzyme complex in utero embryonic development protein kinase inhibitor activity protein kinase inhibitor activity cyclin-dependent protein serine/threonine kinase inhibitor activity protein binding nucleus nucleus nucleus nucleoplasm nucleolus cytoplasm cytosol protein import into nucleus DNA damage response DNA damage response DNA damage response DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator cell cycle mitotic G2 DNA damage checkpoint signaling regulation of mitotic cell cycle regulation of mitotic cell cycle heart development negative regulation of cell population proliferation negative regulation of cell population proliferation epidermis development response to UV regulation of G2/M transition of mitotic cell cycle negative regulation of gene expression nuclear body protein kinase binding cyclin-dependent protein kinase activating kinase activity keratinocyte differentiation negative regulation of cell growth cyclin binding positive regulation of B cell proliferation ubiquitin protein ligase binding cellular response to extracellular stimulus negative regulation of protein binding protein-containing complex cellular response to amino acid starvation cellular response to amino acid starvation wound healing tissue regeneration negative regulation of phosphorylation intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of apoptotic process positive regulation of programmed cell death keratinocyte proliferation protein-containing complex binding negative regulation of cyclin-dependent protein serine/threonine kinase activity negative regulation of cyclin-dependent protein serine/threonine kinase activity positive regulation of protein kinase activity metal ion binding fibroblast proliferation positive regulation of fibroblast proliferation perinuclear region of cytoplasm regulation of cell cycle regulation of cell cycle regulation of cell cycle PCNA-p21 complex cellular response to ionizing radiation cellular response to gamma radiation cellular response to UV-B signal transduction by p53 class mediator cellular senescence cellular senescence oncogene-induced cell senescence oncogene-induced cell senescence protein sequestering activity molecular function activator activity molecular function inhibitor activity regulation of cell cycle G1/S phase transition negative regulation of cyclin-dependent protein kinase activity negative regulation of vascular associated smooth muscle cell proliferation negative regulation of cardiac muscle tissue regeneration regulation of G1/S transition of mitotic cell cycle regulation of G1/S transition of mitotic cell cycle negative regulation of G1/S transition of mitotic cell cycle regulation of DNA biosynthetic process negative regulation of DNA biosynthetic process positive regulation of reactive oxygen species metabolic process	04012 04110 04115 05160 05200 05214 05215 05218 05219 05220
1420497_a_at	Cebpz	CCAAT/enhancer binding protein zeta	17	-78919002	NM_009882	12607	25	transcription coactivator activity nucleus nucleus CCAAT-binding factor complex positive regulation of transcription by RNA polymerase II
1427844_a_at	Cebpb	CCAAT/enhancer binding protein beta	2	167688914	AB012278	12608	583	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II condensed chromosome, centromeric region chromatin transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific ovarian follicle development embryonic placenta development granuloma formation DNA binding DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II positive regulation of gene expression nuclear matrix nuclear matrix kinase binding cell differentiation neuron differentiation chromatin DNA binding response to lipopolysaccharide regulation of interleukin-6 production positive regulation of interleukin-4 production mammary gland epithelial cell proliferation response to endoplasmic reticulum stress histone acetyltransferase binding nuclear glucocorticoid receptor binding T-helper 1 cell activation CHOP-C/EBP complex negative regulation of T cell proliferation defense response to bacterium identical protein binding protein homodimerization activity histone deacetylase binding negative regulation of neuron apoptotic process sequence-specific DNA binding sequence-specific DNA binding ubiquitin-like protein ligase binding fat cell differentiation fat cell differentiation regulation of cell differentiation positive regulation of fat cell differentiation positive regulation of osteoblast differentiation regulation of osteoclast differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein heterodimerization activity positive regulation of inflammatory response brown fat cell differentiation mammary gland epithelial cell differentiation myeloid cell development RNA polymerase II-specific DNA-binding transcription factor binding intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress positive regulation of biomineral tissue development cellular response to lipopolysaccharide cellular response to amino acid stimulus cellular response to interleukin-1 hepatocyte proliferation hepatocyte proliferation RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex liver regeneration positive regulation of cold-induced thermogenesis DNA-binding transcription factor binding regulation of odontoblast differentiation regulation of odontoblast differentiation C/EBP complex C/EBP complex sequence-specific double-stranded DNA binding positive regulation of sodium-dependent phosphate transport regulation of dendritic cell differentiation
1418066_at	Cfl2	cofilin 2, muscle	12	-54858818	AI323758	12632	51	actin binding nucleus cytoplasm cytoplasm cytoskeleton actin filament organization skeletal muscle tissue development actin cytoskeleton actin cytoskeleton Z disc actin filament depolymerization actin filament depolymerization actin filament depolymerization actin filament fragmentation actin filament fragmentation positive regulation of actin filament depolymerization I band sarcomere organization muscle cell cellular homeostasis actin filament severing actin filament binding actin filament binding	04360 04666 04810
1451537_at	Chi3l1	chitinase 3 like 1	1	134182403, 134182155	BC005611	12654	98	protein binding extracellular region extracellular region extracellular space cytoplasm endoplasmic reticulum carbohydrate metabolic process chitin catabolic process apoptotic process inflammatory response activation of NF-kappaB-inducing kinase activity chitin binding chitin binding positive regulation of peptidyl-threonine phosphorylation lung development positive regulation of interleukin-8 production positive regulation of angiogenesis positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of ERK1 and ERK2 cascade	00520
1419764_at	Chil3	chitinase-like 3	3	-106147553	NM_009892	12655	67	polysaccharide catabolic process production of molecular mediator involved in inflammatory response beta-N-acetylhexosaminidase activity extracellular region extracellular region extracellular space nucleus cytoplasm endoplasmic reticulum carbohydrate metabolic process chitin catabolic process chitin catabolic process inflammatory response chitin binding chitin binding metabolic process hydrolase activity hydrolase activity, acting on glycosyl bonds kinase binding carbohydrate binding cytoplasmic vesicle positive regulation of chemokine production N-acetyl-beta-D-galactosaminidase activity
1416332_at	Cirbp	cold inducible RNA binding protein	10	80167838, 80167838, 80167838, 80168170, 80165989	NM_007705	12696	87	nucleic acid binding RNA binding RNA binding mRNA 3'-UTR binding nucleus nucleus nucleoplasm nucleoplasm spliceosomal complex cytoplasm cytoplasm poly(U) RNA binding response to UV cytoplasmic stress granule negative regulation of cell growth translation repressor activity stress granule assembly positive regulation of translation positive regulation of mRNA splicing, via spliceosome mRNA stabilization small ribosomal subunit rRNA binding cellular response to cold regulation of cell cycle G1/S phase transition
1455899_x_at	Socs3	suppressor of cytokine signaling 3	11	-117966086	BB241535	12702	471	phosphotyrosine residue binding regulation of protein phosphorylation protein binding cytosol phosphatidylinositol 3-kinase complex signal transduction receptor signaling pathway via JAK-STAT cytoplasmic side of plasma membrane negative regulation of signal transduction cell differentiation cell differentiation protein tyrosine kinase inhibitor activity miRNA binding miRNA binding intracellular signal transduction negative regulation of tyrosine phosphorylation of STAT protein positive regulation of cell differentiation positive regulation of cell differentiation negative regulation of receptor signaling pathway via JAK-STAT negative regulation of insulin receptor signaling pathway phosphatidylinositol phosphate biosynthetic process 1-phosphatidylinositol-3-kinase regulator activity negative regulation of inflammatory response branching involved in labyrinthine layer morphogenesis placenta blood vessel development cellular response to interleukin-17 cellular response to leukemia inhibitory factor	04120 04380 04630 04910 04920 04930 05160
1450446_a_at	Socs1	suppressor of cytokine signaling 1	16	-10783808	AB000710	12703	327	regulation of cytokine production regulation of protein phosphorylation insulin-like growth factor receptor binding protein binding nucleus nucleoplasm cytosol phosphatidylinositol 3-kinase complex receptor signaling pathway via JAK-STAT negative regulation of signal transduction regulation of activation of Janus kinase activity kinase inhibitor activity cytokine-mediated signaling pathway cytokine-mediated signaling pathway protein kinase binding macrophage differentiation cytoplasmic vesicle intracellular signal transduction cytoplasmic ribonucleoprotein granule regulation of tyrosine phosphorylation of STAT protein negative regulation of tyrosine phosphorylation of STAT protein negative regulation of tyrosine phosphorylation of STAT protein positive regulation of CD4-positive, alpha-beta T cell differentiation negative regulation of CD8-positive, alpha-beta T cell differentiation fat cell differentiation positive regulation of regulatory T cell differentiation regulation of receptor signaling pathway via JAK-STAT negative regulation of receptor signaling pathway via JAK-STAT negative regulation of receptor signaling pathway via JAK-STAT negative regulation of insulin receptor signaling pathway phosphatidylinositol phosphate biosynthetic process 1-phosphatidylinositol-3-kinase regulator activity cellular response to amino acid stimulus cellular response to cytokine stimulus cellular response to organic cyclic compound negative regulation of hepatic stellate cell proliferation positive regulation of fibroblast apoptotic process	04120 04380 04630 04910 04930 05145
1426124_a_at	Clk1	CDC-like kinase 1	1	-58411987	U21209	12747	43	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein tyrosine kinase activity protein binding ATP binding nucleus nucleus protein phosphorylation kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation peptidyl-tyrosine phosphorylation peptidyl-tyrosine phosphorylation regulation of RNA splicing regulation of RNA splicing protein autophosphorylation
1417743_at	Clk2	CDC-like kinase 2	3	89164794	BC015080	12748	35	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein tyrosine kinase activity ATP binding nucleus nucleus nucleus nucleoplasm protein phosphorylation protein phosphorylation response to organic substance response to ionizing radiation kinase activity phosphorylation nuclear body transferase activity peptidyl-tyrosine phosphorylation peptidyl-tyrosine phosphorylation response to retinoic acid identical protein binding regulation of RNA splicing regulation of RNA splicing negative regulation of gluconeogenesis protein autophosphorylation
1422886_a_at	Clk4	CDC like kinase 4	11	51263113	NM_007714	12750	24	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity protein tyrosine kinase activity ATP binding nucleus nucleus protein phosphorylation kinase activity phosphorylation transferase activity peptidyl-tyrosine phosphorylation peptidyl-tyrosine phosphorylation regulation of RNA splicing regulation of RNA splicing protein autophosphorylation
1421734_at	Cxcr2	C-X-C motif chemokine receptor 2	1	74153993	NM_009909	12765	350	acute inflammatory response to antigenic stimulus positive regulation of leukocyte chemotaxis interleukin-8 receptor activity interleukin-8 receptor activity G protein-coupled receptor activity chemokine receptor activity chemokine receptor activity protein binding nucleoplasm plasma membrane chemotaxis chemotaxis immune response cellular defense response signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration positive regulation of cell population proliferation external side of plasma membrane cell surface positive regulation of cardiac muscle cell apoptotic process microtubule cytoskeleton membrane C-C chemokine receptor activity C-X-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding interleukin-8 binding neutrophil chemotaxis neutrophil chemotaxis receptor internalization negative regulation of neutrophil apoptotic process interleukin-8-mediated signaling pathway neutrophil activation mast cell granule negative regulation of apoptotic process negative regulation of apoptotic process positive regulation of vascular permeability positive regulation of angiogenesis metanephric tubule morphogenesis mitotic spindle positive regulation of neutrophil chemotaxis	04060 04062 04144
1449925_at	Cxcr3	C-X-C motif chemokine receptor 3	X	-101731534	NM_009910	12766	339	angiogenesis negative regulation of endothelial cell proliferation regulation of leukocyte migration G protein-coupled receptor activity chemokine receptor activity plasma membrane chemotaxis inflammatory response immune response signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration positive regulation of cell population proliferation external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface cell surface T cell chemotaxis membrane C-C chemokine receptor activity C-X-C chemokine receptor activity negative regulation of angiogenesis calcium-mediated signaling calcium-mediated signaling chemokine binding C-C chemokine binding C-X-C chemokine binding regulation of cell adhesion signaling receptor activity positive regulation of angiogenesis positive regulation of transcription by RNA polymerase II positive regulation of chemotaxis positive regulation of release of sequestered calcium ion into cytosol cell chemotaxis negative regulation of execution phase of apoptosis positive regulation of execution phase of apoptosis	04060 04062
1448710_at	Cxcr4	C-X-C motif chemokine receptor 4	1	-128588198	D87747	12767	672	branching involved in blood vessel morphogenesis neuron migration neuron migration kidney development positive regulation of protein phosphorylation epithelial cell development ventricular septum development actin binding G protein-coupled receptor activity chemokine receptor activity protein binding lysosome endosome early endosome late endosome plasma membrane plasma membrane cell-cell junction chemotaxis immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration germ cell development nervous system development brain development brain development motor neuron axon guidance germ cell migration animal organ morphogenesis external side of plasma membrane external side of plasma membrane cell surface cell surface response to organic cyclic compound membrane cell migration C-C chemokine receptor activity calcium-mediated signaling calcium-mediated signaling cytokine binding C-C chemokine binding C-C chemokine binding neurogenesis neurogenesis telencephalon cell migration regulation of cell adhesion regulation of cell migration regulation of cell migration positive regulation of cell migration growth cone cell leading edge cytoplasmic vesicle ubiquitin protein ligase binding myosin light chain binding protein-containing complex positive regulation of vascular wound healing hematopoietic stem cell migration aorta development small molecule binding C-X-C motif chemokine 12 receptor activity CXCL12-activated CXCR4 signaling pathway CXCL12-activated CXCR4 signaling pathway T cell proliferation regulation of programmed cell death ubiquitin binding myelin maintenance blood vessel endothelial cell migration endothelial cell differentiation generation of neurons positive regulation of oligodendrocyte differentiation positive regulation of neurogenesis regulation of viral process regulation of chemotaxis positive regulation of chemotaxis detection of temperature stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of pain regulation of calcium ion transport cardiac muscle contraction cell chemotaxis endothelial tube morphogenesis neural precursor cell proliferation anchoring junction positive regulation of ERK1 and ERK2 cascade cellular response to cytokine stimulus cellular response to cytokine stimulus cellular response to organonitrogen compound positive regulation of calcium ion import positive regulation of cold-induced thermogenesis response to tacrolimus positive regulation of dendrite extension positive regulation of vasculature development positive regulation of mesenchymal stem cell migration positive regulation of macrophage migration inhibitory factor signaling pathway regulation of neuron migration	04060 04062 04144 04360 04670 04672
1419609_at	Ccr1	C-C motif chemokine receptor 1	9	-123962125	AV231648	12768	160	phosphatidylinositol phospholipase C activity G protein-coupled receptor activity chemokine receptor activity protein binding cytoplasm plasma membrane calcium ion transport intracellular calcium ion homeostasis exocytosis chemotaxis inflammatory response inflammatory response immune response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration cell-cell signaling external side of plasma membrane external side of plasma membrane negative regulation of gene expression membrane C-C chemokine receptor activity C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding myeloid cell differentiation positive regulation of cell migration negative regulation of bone mineralization leukocyte chemotaxis leukocyte chemotaxis chemokine (C-C motif) ligand 7 binding chemokine (C-C motif) ligand 7 binding neuronal cell body positive regulation of osteoclast differentiation negative regulation of innate immune response positive regulation of calcium ion transport cell chemotaxis chemokine-mediated signaling pathway positive regulation of ERK1 and ERK2 cascade chemokine (C-C motif) ligand 5 binding chemokine (C-C motif) ligand 5 binding positive regulation of monocyte chemotaxis	04060 04062
1427419_x_at	Ccr9	C-C motif chemokine receptor 9	9	123767210	AJ131357	12769	95	CD8-positive, gamma-delta intraepithelial T cell differentiation G protein-coupled receptor activity chemokine receptor activity protein binding plasma membrane chemotaxis immune response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration external side of plasma membrane cell surface membrane C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding cell chemotaxis	04060 04062 04672
1424727_at	Ccr5	C-C motif chemokine receptor 5	9	124121542	D83648	12774	379	actin binding G protein-coupled receptor activity chemokine receptor activity cytoplasm endosome plasma membrane calcium ion transport chemotaxis defense response inflammatory response inflammatory response immune response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration cell-cell signaling external side of plasma membrane external side of plasma membrane external side of plasma membrane cell surface cell surface positive regulation of gene expression release of sequestered calcium ion into cytosol by sarcoplasmic reticulum membrane C-C chemokine receptor activity C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling calcium-mediated signaling protein kinase binding C-C chemokine binding C-C chemokine binding positive regulation of cell-cell adhesion regulation of cell migration negative regulation of axon extension positive regulation of cell killing positive regulation of fever generation positive regulation of interleukin-1 beta production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production identical protein binding positive regulation of neuron differentiation cell chemotaxis response to cholesterol chemokine (C-C motif) ligand 5 binding chemokine (C-C motif) ligand 5 binding negative regulation of macrophage apoptotic process negative regulation of neural precursor cell proliferation	04060 04062 04144 05145
1423466_at	Ccr7	C-C motif chemokine receptor 7	11	-99144198	BB204380	12775	392	establishment of T cell polarity myeloid dendritic cell chemotaxis lymphocyte chemotaxis across high endothelial venule positive regulation of dendritic cell antigen processing and presentation regulation of tolerance induction to self antigen positive regulation of hypersensitivity positive regulation of humoral immune response G protein-coupled receptor activity chemokine receptor activity protein binding mitochondrion plasma membrane plasma membrane chemotaxis inflammatory response inflammatory response immune response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration external side of plasma membrane external side of plasma membrane cell surface cell surface positive regulation of macrophage chemotaxis positive regulation of T cell chemotaxis membrane C-C chemokine receptor activity calcium-mediated signaling actin cytoskeleton organization response to lipopolysaccharide regulation of type II interferon production regulation of interleukin-1 beta production negative regulation of interleukin-12 production positive regulation of interleukin-1 beta production positive regulation of interleukin-12 production positive regulation of tumor necrosis factor production response to prostaglandin E chemokine (C-C motif) ligand 19 binding chemokine (C-C motif) ligand 19 binding chemokine (C-C motif) ligand 21 binding chemokine (C-C motif) ligand 21 binding C-C motif chemokine 19 receptor activity C-C motif chemokine 19 receptor activity C-C motif chemokine 21 receptor activity positive regulation of T cell proliferation positive regulation of JUN kinase activity positive regulation of GTPase activity negative thymic T cell selection positive regulation of T-helper 1 cell differentiation positive regulation of receptor-mediated endocytosis lymph node development homeostasis of number of cells positive regulation of phagocytosis positive regulation of T cell receptor signaling pathway positive regulation of filopodium assembly cell chemotaxis cellular response to cytokine stimulus response to nitric oxide positive regulation of neutrophil chemotaxis positive regulation of neutrophil chemotaxis lymphocyte migration into lymph node mature conventional dendritic cell differentiation negative regulation of leukocyte apoptotic process positive regulation of cell motility positive regulation of thymocyte migration positive regulation of dendritic cell chemotaxis positive regulation of immunological synapse formation positive regulation of T cell costimulation positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation regulation of dendritic cell dendrite assembly	04060 04062
1419691_at	Camp	cathelicidin antimicrobial peptide	9	-109847376	NM_009921	12796	135	lipopolysaccharide binding response to yeast positive regulation of protein phosphorylation innate immune response in mucosa immune system process chronic inflammatory response extracellular region extracellular space extracellular space defense response positive regulation of cell population proliferation antibacterial humoral response antifungal humoral response cytolysis positive regulation of interleukin-8 production modulation of process of another organism neutrophil activation specific granule specific granule defense response to bacterium defense response to bacterium cell projection innate immune response innate immune response innate immune response positive regulation of angiogenesis defense response to Gram-negative bacterium defense response to Gram-negative bacterium defense response to Gram-negative bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium cytolysis by host of symbiont cells killing by host of symbiont cells killing by host of symbiont cells antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide amyloid fibril formation	04970
1416740_at	Col5a1	collagen, type V, alpha 1	2	27886424	AW744319	12831	97	blood vessel development heart morphogenesis extracellular matrix structural constituent protein binding extracellular region collagen trimer collagen trimer collagen type V trimer collagen type V trimer collagen type XI trimer basement membrane extracellular space extracellular space cell adhesion cell adhesion heparin binding heparin binding cell migration extracellular matrix structural constituent conferring tensile strength extracellular matrix structural constituent conferring tensile strength collagen fibril organization collagen fibril organization collagen fibril organization collagen fibril organization extracellular matrix collagen biosynthetic process wound healing, spreading of epidermal cells tendon development tendon development proteoglycan binding skin development skin development integrin biosynthetic process platelet-derived growth factor binding eye morphogenesis regulation of cellular component organization collagen-containing extracellular matrix collagen-containing extracellular matrix collagen-containing extracellular matrix collagen-containing extracellular matrix supramolecular fiber organization negative regulation of endodermal cell differentiation	04510 04512 04974 05146
1459885_s_at	Cox7c	cytochrome c oxidase subunit 7C	13	-86044797	AA190297	12867	32	protein binding mitochondrion mitochondrial inner membrane mitochondrial respiratory chain complex IV mitochondrial respiratory chain complex IV mitochondrial electron transport, cytochrome c to oxygen mitochondrial electron transport, cytochrome c to oxygen membrane mitochondrial membrane	00190 01100 04260 05010 05012 05016
1455393_at	Cp	ceruloplasmin	3	19957053, 19957053, 19957053, 19957248	BB009037	12870	105	ferroxidase activity ferroxidase activity glutathione peroxidase activity copper ion binding copper ion binding extracellular region extracellular space extracellular space extracellular space plasma membrane monoatomic ion transport copper ion transport iron ion transport intracellular copper ion homeostasis intracellular iron ion homeostasis cell surface oxidoreductase activity oxidoreductase activity oxidoreductase activity, acting on metal ions, oxygen as acceptor response to copper ion metal ion binding phospholipid-hydroperoxide glutathione peroxidase activity protein-folding chaperone binding	00860
1448730_at	Cpa3	carboxypeptidase A3, mast cell	3	-20215615	NM_007753	12873	65	regulation of angiotensin levels in blood carboxypeptidase activity metallocarboxypeptidase activity metallocarboxypeptidase activity extracellular space proteolysis proteolysis peptidase activity metallopeptidase activity zinc ion binding hydrolase activity cytoplasmic vesicle metal ion binding	04614 04972 04974
1455009_at	Cpd	carboxypeptidase D	11	-76777207	AW550842	12874	24	carboxypeptidase activity metallocarboxypeptidase activity metallocarboxypeptidase activity extracellular space nucleus trans-Golgi network plasma membrane proteolysis peptide metabolic process peptidase activity metallopeptidase activity zinc ion binding membrane protein processing hydrolase activity protein-containing complex binding metal ion binding perinuclear region of cytoplasm protein phosphatase 2A binding
1425289_a_at	Cr2	complement receptor 2	1	-195136811	M35684	12902	184	complement binding immune system process T cell mediated immunity DNA binding complement receptor activity protein binding extracellular space extracellular space plasma membrane plasma membrane inflammatory response complement activation, alternative pathway complement activation, alternative pathway complement activation, classical pathway external side of plasma membrane cell surface membrane immunoglobulin mediated immune response B cell differentiation immunoglobulin receptor binding signaling receptor activity B cell proliferation protein homodimerization activity receptor complex innate immune response negative regulation of complement activation, classical pathway cartilage development bone development cellular response to lipopolysaccharide	04610 04640 04662
1449037_at	Crem	cAMP responsive element modulator	18	-3294165, -3266353, -3266353, -3266353, -3266353, -3266353	AI467599	12916	157	negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus transcription regulator complex cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II glycosphingolipid metabolic process spermatogenesis spermatogenesis circadian rhythm circadian regulation of gene expression negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II rhythmic process response to cAMP ATF4-CREB1 transcription factor complex sequence-specific double-stranded DNA binding
1416326_at	Crip1	cysteine-rich protein 1	12	113152011	NM_007763	12925	34	cytoplasm cytoplasm zinc ion binding zinc ion binding zinc ion binding intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage response to zinc ion response to zinc ion regulation of gene expression peptide binding peptide binding metal ion binding cellular response to antibiotic cellular response to antibiotic cellular response to UV-B cellular response to UV-B
1421946_at	Crp	C-reactive protein, pentraxin-related	1	172698055	NM_007768	12944	92	complement component C1q complex binding complement component C1q complex binding calcium ion binding extracellular region extracellular space extracellular space acute-phase response complement activation, classical pathway positive regulation of gene expression negative regulation of macrophage derived foam cell differentiation negative regulation of lipid storage regulation of low-density lipoprotein particle clearance cholesterol binding low-density lipoprotein particle binding low-density lipoprotein particle binding filopodium growth cone regulation of interleukin-8 production negative regulation of superoxide anion generation positive regulation of superoxide anion generation negative regulation of mononuclear cell proliferation vasoconstriction identical protein binding innate immune response positive regulation of nitric oxide biosynthetic process metal ion binding low-density lipoprotein particle receptor binding protein polymerization cellular response to calcium ion positive regulation of dendrite development
1420703_at	Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	19	-61224401	BM941868	12982	48	cytokine receptor activity receptor signaling pathway via JAK-STAT membrane granulocyte macrophage colony-stimulating factor receptor complex granulocyte-macrophage colony-stimulating factor signaling pathway positive regulation of leukocyte proliferation	04060 04630 04640 05200
1455660_at	Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	15	78325799, 78325989	BB769628	12983	153	regulation of cell growth cytokine receptor activity cytokine receptor activity protein binding plasma membrane receptor signaling pathway via JAK-STAT external side of plasma membrane coreceptor activity membrane immunoglobulin mediated immune response cytokine-mediated signaling pathway cytokine-mediated signaling pathway granulocyte macrophage colony-stimulating factor receptor complex interleukin-5-mediated signaling pathway interleukin-3-mediated signaling pathway granulocyte-macrophage colony-stimulating factor signaling pathway positive regulation of leukocyte proliferation	04060 04210 04630
1449360_at	Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	15	-78282507	NM_007781	12984	59	cytokine receptor activity cytokine receptor activity plasma membrane plasma membrane receptor signaling pathway via JAK-STAT external side of plasma membrane coreceptor activity membrane immunoglobulin mediated immune response cytokine-mediated signaling pathway cytokine-mediated signaling pathway granulocyte macrophage colony-stimulating factor receptor complex interleukin-5-mediated signaling pathway interleukin-3-mediated signaling pathway granulocyte-macrophage colony-stimulating factor signaling pathway positive regulation of leukocyte proliferation	04060 04210 04630
1427256_at	Vcan	versican	13	-89655309, -89709947	BM251152	13003	224	skeletal system development ureteric bud development positive regulation of neuroblast proliferation calcium ion binding hyaluronic acid binding extracellular region extracellular space cell adhesion central nervous system development heart development glial cell migration cell surface glial cell differentiation protein phosphatase binding extracellular matrix structural constituent conferring compression resistance carbohydrate binding extracellular matrix cell projection regulation of phosphoprotein phosphatase activity synapse synapse collagen-containing extracellular matrix collagen-containing extracellular matrix perineuronal net perineuronal net	04514
1422506_a_at	Cstb	cystatin B	10	78425669	NM_007793	13014	60	protease binding endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity extracellular space nucleus nucleolus cytoplasm cytosol cytosol adult locomotory behavior negative regulation of peptidase activity peptidase inhibitor activity negative regulation of proteolysis collagen-containing extracellular matrix
1434705_at	Ctbp2	C-terminal binding protein 2	7	-132987010, -132987010, -132987010	BG072903	13017	152	transcription coregulator binding transcription coregulator binding transcription corepressor binding chromatin binding transcription coactivator activity transcription coactivator activity transcription corepressor activity transcription corepressor activity transcription corepressor activity protein binding nucleus nucleus nucleus cytosol regulation of transcription by RNA polymerase II synaptic vesicle docking synaptic vesicle docking oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor transcription repressor complex protein kinase binding cell differentiation positive regulation of chromatin binding identical protein binding nuclear retinoic acid receptor binding protein-containing complex binding synapse negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of retinoic acid receptor signaling pathway positive regulation of retinoic acid receptor signaling pathway white fat cell differentiation NAD binding ribbon synapse photoreceptor ribbon synapse photoreceptor ribbon synapse photoreceptor ribbon synapse presynaptic active zone cytoplasmic component structural constituent of presynaptic active zone structural constituent of presynaptic active zone glutamatergic synapse glutamatergic synapse GABA-ergic synapse presynaptic cytosol DNA-binding transcription factor binding cellular response to leukemia inhibitory factor	04310 04330 05200 05220
1416382_at	Ctsc	cathepsin C	7	88278084, 88278084	NM_009982	13032	79	T cell mediated cytotoxicity cysteine-type endopeptidase activity serine-type endopeptidase activity extracellular space nucleoplasm cytoplasm lysosome lysosome centrosome proteolysis proteolysis peptidase activity cysteine-type peptidase activity cysteine-type peptidase activity dipeptidyl-peptidase activity response to organic substance peptidase activator activity involved in apoptotic process hydrolase activity phosphatase binding chloride ion binding negative regulation of myelination negative regulation of myelination identical protein binding intracellular membrane-bounded organelle protein self-association protein-folding chaperone binding proteolysis involved in protein catabolic process collagen-containing extracellular matrix positive regulation of proteolysis involved in protein catabolic process positive regulation of microglial cell activation positive regulation of apoptotic signaling pathway	04142
1451310_a_at	Ctsl	cathepsin L	13	-64361889	J02583	13039	221	fibronectin binding endopeptidase activity aminopeptidase activity cysteine-type endopeptidase activity cysteine-type endopeptidase activity protein binding collagen binding extracellular region extracellular space extracellular space extracellular space nucleus nucleolus lysosome lysosome lysosome multivesicular body Golgi apparatus plasma membrane microvillus proteolysis proteolysis thyroid hormone generation immune response peptidase activity cysteine-type peptidase activity cysteine-type endopeptidase activator activity involved in apoptotic process external side of plasma membrane external side of plasma membrane negative regulation of keratinocyte proliferation positive regulation of peptidase activity membrane hydrolase activity cysteine-type carboxypeptidase activity secretory granule protein catabolic process collagen catabolic process kininogen binding hair follicle morphogenesis cytoplasmic vesicle peptide binding histone binding histone binding catagen perikaryon intracellular membrane-bounded organelle CD4-positive, alpha-beta T cell lineage commitment proteoglycan binding keratinocyte proliferation protein-containing complex binding apical part of cell decidualization antigen processing and presentation of peptide antigen proteolysis involved in protein catabolic process proteolysis involved in protein catabolic process elastin catabolic process collagen-containing extracellular matrix serpin family protein binding positive regulation of apoptotic signaling pathway	04142 04145 04612 05323
1454268_a_at	Cyba	cytochrome b-245, alpha polypeptide	8	-122424770	AK018713	13057	75	stress fiber positive regulation of endothelial cell proliferation negative regulation of glomerular filtration by angiotensin protein binding cytoplasm mitochondrion endosome plasma membrane focal adhesion superoxide metabolic process inflammatory response electron transfer activity smooth muscle hypertrophy membrane superoxide-generating NAD(P)H oxidase activity apical plasma membrane oxidoreductase activity cytochrome complex assembly SH3 domain binding heme binding positive regulation of cell growth dendrite positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of superoxide anion generation positive regulation of toll-like receptor 2 signaling pathway superoxide anion generation superoxide anion generation NADPH oxidase complex NADPH oxidase complex NADPH oxidase complex neuronal cell body innate immune response innate immune response respiratory burst positive regulation of blood pressure metal ion binding protein heterodimerization activity positive regulation of smooth muscle cell proliferation hydrogen peroxide biosynthetic process positive regulation of phagocytosis regulation of release of sequestered calcium ion into cytosol establishment of localization in cell mucus secretion positive regulation of mucus secretion cellular response to organic substance reactive oxygen species metabolic process perinuclear endoplasmic reticulum positive regulation of defense response to bacterium positive regulation of reactive oxygen species biosynthetic process	04145 04380 04670 05140
1422978_at	Cybb	cytochrome b-245, beta polypeptide	X	-9435253	NM_007807	13058	775	protein binding nuclear envelope cytoplasm mitochondrion plasma membrane plasma membrane plasma membrane superoxide metabolic process superoxide metabolic process monoatomic ion transport defense response inflammatory response electron transfer activity response to xenobiotic stimulus membrane superoxide-generating NAD(P)H oxidase activity superoxide-generating NAD(P)H oxidase activity superoxide-generating NAD(P)H oxidase activity oxidoreductase activity heme binding dendrite positive regulation of tumor necrosis factor production monoatomic ion transmembrane transport monoatomic ion channel complex superoxide anion generation superoxide anion generation NADPH oxidase complex NADPH oxidase complex NADPH oxidase complex neuronal cell body innate immune response innate immune response phagocytic vesicle respiratory burst positive regulation of angiogenesis metal ion binding protein heterodimerization activity flavin adenine dinucleotide binding hydrogen peroxide biosynthetic process perinuclear endoplasmic reticulum hypoxia-inducible factor-1alpha signaling pathway	04145 04380 04670
1425645_s_at	Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	7	25897657	AF128849	13088	63	monooxygenase activity iron ion binding cytoplasm mitochondrial inner membrane endoplasmic reticulum xenobiotic metabolic process xenobiotic metabolic process steroid metabolic process testosterone 16-alpha-hydroxylase activity arachidonic acid epoxygenase activity steroid hydroxylase activity response to bacterium membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen epoxygenase P450 pathway heme binding heme binding Hsp70 protein binding xenobiotic catabolic process cellular ketone metabolic process intracellular membrane-bounded organelle intracellular membrane-bounded organelle metal ion binding Hsp90 protein binding testosterone 16-beta-hydroxylase activity anandamide 8,9 epoxidase activity anandamide 11,12 epoxidase activity anandamide 14,15 epoxidase activity aromatase activity estrogen 2-hydroxylase activity	00590 00830 00980 00982 01100
1415994_at	Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	7	140763818	NM_021282	13106	179	Golgi membrane long-chain fatty acid metabolic process lipid hydroxylation monooxygenase activity monooxygenase activity iron ion binding cytoplasm mitochondrion mitochondrial inner membrane endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process fatty acid metabolic process triglyceride metabolic process xenobiotic metabolic process xenobiotic metabolic process steroid metabolic process arachidonic acid epoxygenase activity response to bacterium membrane monoterpenoid metabolic process oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 4-nitrophenol 2-monooxygenase activity 4-nitrophenol metabolic process epoxygenase P450 pathway enzyme binding heme binding heme binding Hsp70 protein binding intracellular membrane-bounded organelle intracellular membrane-bounded organelle heterocycle metabolic process metal ion binding Hsp90 protein binding aromatase activity long-chain fatty acid omega-1 hydroxylase activity	00590 00591 00980 00982 01100
1416809_at	Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	5	-145854606	BC010528	13112	63	lipid hydroxylation monooxygenase activity monooxygenase activity iron ion binding endoplasmic reticulum endoplasmic reticulum membrane steroid metabolic process steroid metabolic process estrogen metabolic process retinoic acid 4-hydroxylase activity response to bacterium alkaloid catabolic process membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen heme binding demethylase activity xenobiotic catabolic process retinoic acid metabolic process intracellular membrane-bounded organelle metal ion binding testosterone 6-beta-hydroxylase activity testosterone 6-beta-hydroxylase activity aromatase activity oxidative demethylation oxidative demethylation estrogen 16-alpha-hydroxylase activity	00140 00591 00830 00980 00982 00983 01100
1420498_a_at	Dab2	disabled 2, mitogen-responsive phosphoprotein	15	6386747, 6299788	NM_023118	13132	128	negative regulation of transcription by RNA polymerase II cell morphogenesis fibrillar center in utero embryonic development positive regulation of receptor recycling positive regulation of protein phosphorylation positive regulation of receptor internalization integrin binding protein binding phosphatidylinositol-4,5-bisphosphate binding cytoplasm plasma membrane plasma membrane clathrin-coated pit clathrin-coated pit endocytosis receptor-mediated endocytosis receptor-mediated endocytosis apoptotic process transforming growth factor beta receptor signaling pathway multicellular organism development positive regulation of epithelial to mesenchymal transition positive regulation of epithelial to mesenchymal transition positive regulation of epithelial to mesenchymal transition negative regulation of neuron projection development protein transport membrane Wnt signaling pathway apical plasma membrane myeloid cell differentiation clathrin coat of coated pit clathrin-coated vesicle cell differentiation clathrin binding negative regulation of cell growth positive regulation of cell migration positive regulation of cell migration clathrin-coated vesicle membrane cytoplasmic vesicle negative regulation of protein binding positive regulation of aldosterone biosynthetic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of transcription elongation by RNA polymerase II leading edge cell differentiation phosphatidylinositol binding AP-2 adaptor complex binding clathrin adaptor activity clathrin adaptor activity clathrin adaptor activity cargo receptor activity cargo receptor activity cargo receptor activity negative regulation of apoptotic process negative regulation of apoptotic process intracellular membrane-bounded organelle intracellular membrane-bounded organelle positive regulation of cell adhesion positive regulation of cell adhesion positive regulation of endocytosis positive regulation of endocytosis positive regulation of transcription by RNA polymerase II positive regulation of JNK cascade SMAD binding clathrin coat assembly clathrin coat assembly perinuclear region of cytoplasm response to steroid hormone negative regulation of epithelial cell proliferation low-density lipoprotein particle receptor binding positive regulation of SMAD protein signal transduction negative regulation of androgen receptor signaling pathway negative regulation of ERK1 and ERK2 cascade cellular response to epidermal growth factor stimulus hematopoietic stem cell proliferation cellular response to transforming growth factor beta stimulus negative regulation of canonical Wnt signaling pathway negative regulation of canonical Wnt signaling pathway renal protein absorption extrinsic apoptotic signaling pathway positive regulation of substrate adhesion-dependent cell spreading positive regulation of substrate adhesion-dependent cell spreading positive regulation of substrate adhesion-dependent cell spreading negative regulation of protein localization to plasma membrane negative regulation of protein localization to plasma membrane positive regulation of Wnt signaling pathway, planar cell polarity pathway positive regulation of clathrin-dependent endocytosis positive regulation of clathrin-dependent endocytosis positive regulation of early endosome to late endosome transport positive regulation of aldosterone secretion positive regulation of integrin-mediated signaling pathway negative regulation of extrinsic apoptotic signaling pathway	04144
1433743_at	Dach1	dachshund family transcription factor 1	14	-97786845	BG075820	13134	88	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific suckling behavior DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm transcription regulator complex transcription regulator complex transcription regulator complex cytoplasm Golgi apparatus cytosol regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II multicellular organism development respiratory gaseous exchange by respiratory system negative regulation of transcription by competitive promoter binding nuclear speck negative regulation of cell migration regulation of nuclear cell cycle DNA replication type B pancreatic cell proliferation negative regulation of DNA-templated transcription development of primary female sexual characteristics negative regulation of fibroblast proliferation negative regulation of fibroblast proliferation epithelial cell proliferation negative regulation of cell proliferation involved in contact inhibition negative regulation of DNA biosynthetic process
1418762_at	Cd55	CD55 molecule, decay accelerating factor for complement	1	-130439025	NM_010016	13136	115	virus receptor activity immune system process positive regulation of T cell cytokine production enzyme inhibitor activity plasma membrane complement activation, classical pathway positive regulation of cytosolic calcium ion concentration lipid binding external side of plasma membrane cell surface membrane apical plasma membrane regulation of complement activation regulation of complement activation, classical pathway regulation of lipopolysaccharide-mediated signaling pathway innate immune response membrane raft negative regulation of complement activation side of membrane regulation of complement-dependent cytotoxicity positive regulation of CD4-positive, alpha-beta T cell activation positive regulation of CD4-positive, alpha-beta T cell proliferation	04610 04640 05416
1418578_at	Dgka	diacylglycerol kinase, alpha	10	-128720135, -128720135, -128720135, -128720135	BC006713	13139	62	nucleotide binding ATP-dependent diacylglycerol kinase activity ATP-dependent diacylglycerol kinase activity ATP-dependent diacylglycerol kinase activity calcium ion binding ATP binding phospholipid binding cytoplasm cytosol cytosol plasma membrane plasma membrane lipid metabolic process phosphatidic acid biosynthetic process signal transduction protein kinase C-activating G protein-coupled receptor signaling pathway lipid binding kinase activity phosphorylation transferase activity intracellular signal transduction diacylglycerol metabolic process diacylglycerol metabolic process glycerolipid metabolic process lipid phosphorylation lipid phosphorylation metal ion binding	00561 00564 01100 04070
1422432_at	Dbi	diazepam binding inhibitor	1	-120113279, -120113279	NM_007830	13167	78	fatty-acyl-CoA binding fatty-acyl-CoA binding behavioral fear response hair follicle development extracellular space mitochondrion endoplasmic reticulum Golgi apparatus fatty acid metabolic process triglyceride metabolic process learning or memory synaptic vesicle lipid binding glial cell proliferation lateral ventricle development benzodiazepine receptor binding negative regulation of fatty acid beta-oxidation regulation of synaptic transmission, GABAergic protein-lipid complex long-chain fatty acyl-CoA binding phosphatidylcholine acyl-chain remodeling identical protein binding contractile fiber skin development positive regulation of lipid biosynthetic process positive regulation of release of sequestered calcium ion into cytosol long-term synaptic potentiation perinuclear endoplasmic reticulum negative regulation of protein lipidation positive regulation of CoA-transferase activity positive regulation of phospholipid transport	03320
1438211_s_at	Dbp	D site albumin promoter binding protein	7	45705246	BB550183	13170	83	RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II circadian rhythm positive regulation of transcription by RNA polymerase II rhythmic process RNA polymerase II transcription regulator complex sequence-specific double-stranded DNA binding
1416145_at	Dhx15	DEAH-box helicase 15	5	-52150202, -52153323	BC003745	13204	47	nucleotide binding immune system process nucleic acid binding RNA binding RNA binding RNA helicase activity double-stranded RNA binding helicase activity helicase activity protein binding ATP binding intracellular anatomical structure nucleus spliceosomal complex U12-type spliceosomal complex mRNA processing RNA splicing nuclear speck hydrolase activity defense response to bacterium positive regulation of canonical NF-kappaB signal transduction innate immune response defense response to virus defense response to virus defense response to virus U2-type post-mRNA release spliceosomal complex antiviral innate immune response antiviral innate immune response antiviral innate immune response	03040
1423645_a_at	Ddx5	DEAD box helicase 5	11	-106780355, -106780354, -106780354	BC009142	13207	112	negative regulation of transcription by RNA polymerase II nucleotide binding alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome nuclear-transcribed mRNA catabolic process epithelial to mesenchymal transition nucleic acid binding transcription coregulator activity RNA binding RNA helicase activity RNA helicase activity mRNA 3'-UTR binding mRNA 3'-UTR binding helicase activity protein binding calmodulin binding ATP binding nucleus nucleus nucleus nucleoplasm spliceosomal complex nucleolus cytoplasm cytoplasm regulation of transcription by RNA polymerase II mRNA processing protein import into nucleus circadian rhythm RNA splicing mRNA transcription nuclear speck hydrolase activity enzyme binding BMP signaling pathway intracellular estrogen receptor signaling pathway androgen receptor signaling pathway primary miRNA processing MH2 domain binding pre-mRNA binding ribonucleoprotein complex binding ribonucleoprotein complex binding positive regulation of DNA damage response, signal transduction by p53 class mediator regulation of viral genome replication myoblast differentiation regulation of osteoblast differentiation positive regulation of DNA-templated transcription SMAD binding calcium-dependent protein binding rhythmic process nuclear androgen receptor binding regulation of androgen receptor signaling pathway miRNA transcription R-SMAD binding primary miRNA binding catalytic step 2 spliceosome intrinsic apoptotic signaling pathway by p53 class mediator promoter-specific chromatin binding ribonucleoprotein complex ribonucleoprotein complex regulation of skeletal muscle cell differentiation	03040
1424936_a_at	Dnah8	dynein, axonemal, heavy chain 8	17	30626935	AF356522	13417	28	nucleotide binding microtubule motor activity ATP binding cytoplasm cytoskeleton microtubule cilium axoneme microtubule-based movement minus-end-directed microtubule motor activity minus-end-directed microtubule motor activity ATP hydrolysis activity dynein complex motile cilium sperm flagellum sperm flagellum outer dynein arm outer dynein arm outer dynein arm assembly cell projection dynein intermediate chain binding dynein intermediate chain binding dynein light intermediate chain binding dynein light intermediate chain binding cilium movement involved in cell motility
1438279_at	Dpp4	dipeptidylpeptidase 4	2	-62330072, -62333222	BB532984	13482	226	virus receptor activity behavioral fear response response to hypoxia protease binding B-1a B cell differentiation regulation of T cell mediated immunity positive regulation of natural killer cell mediated immunity aminopeptidase activity serine-type endopeptidase activity signaling receptor binding collagen binding extracellular region plasma membrane plasma membrane proteolysis proteolysis cell adhesion peptidase activity serine-type peptidase activity dipeptidyl-peptidase activity dipeptidyl-peptidase activity positive regulation of cell population proliferation cell surface negative regulation of extracellular matrix disassembly membrane apical plasma membrane hydrolase activity lamellipodium endocytic vesicle protein catabolic process T cell costimulation regulation of cell-cell adhesion mediated by integrin locomotory exploration behavior psychomotor behavior T cell activation peptide binding identical protein binding protein homodimerization activity cell projection endothelial cell migration chemorepellent activity intercellular canaliculus anchoring junction negative regulation of neutrophil chemotaxis	04974
1437301_a_at	Dvl1	dishevelled segment polarity protein 1	4	155847401	BB153808	13542	151	regulation of protein phosphorylation negative regulation of protein phosphorylation positive regulation of protein phosphorylation heart looping outflow tract morphogenesis frizzled binding frizzled binding protein binding cytoplasm cytosol cytosol cytosol microtubule plasma membrane neurotransmitter secretion multicellular organism development axonogenesis axon guidance neuromuscular junction development beta-catenin binding positive regulation of neuron projection development postsynaptic density postsynaptic density postsynaptic density microtubule cytoskeleton microtubule cytoskeleton membrane Wnt signaling pathway synaptic vesicle exocytosis lateral plasma membrane enzyme binding protein kinase binding protein kinase binding convergent extension involved in neural plate elongation clathrin-coated vesicle axon axon dendrite growth cone cytoplasmic microtubule organization cytoplasmic microtubule organization small GTPase binding cytoplasmic vesicle cytoplasmic vesicle social behavior protein localization to microtubule intracellular signal transduction identical protein binding neuron projection neuronal cell body receptor clustering dendritic spine synapse collateral sprouting axon extension dendrite morphogenesis synapse organization synapse organization protein stabilization convergent extension involved in organogenesis convergent extension involved in organogenesis canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway Wnt signaling pathway, planar cell polarity pathway Wnt signaling pathway, planar cell polarity pathway Wnt signaling pathway, planar cell polarity pathway prepulse inhibition dendritic spine morphogenesis skeletal muscle acetylcholine-gated channel clustering cochlea morphogenesis planar cell polarity pathway involved in neural tube closure planar cell polarity pathway involved in neural tube closure Schaffer collateral - CA1 synapse Schaffer collateral - CA1 synapse Schaffer collateral - CA1 synapse presynapse presynapse glutamatergic synapse glutamatergic synapse glutamatergic synapse neuronal dense core vesicle neuronal dense core vesicle presynapse assembly presynapse assembly postsynapse organization postsynapse organization regulation of postsynapse organization regulation of postsynapse organization positive regulation of neuron projection arborization Wnt signalosome regulation of synaptic vesicle exocytosis regulation of synaptic vesicle exocytosis regulation of synaptic vesicle exocytosis positive regulation of excitatory postsynaptic potential	04310 04330 04916 05200 05217
1417444_at	E2f5	E2F transcription factor 5	3	14578670	BC003220	13559	59	G1/S transition of mitotic cell cycle RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity fibrillar center DNA binding DNA-binding transcription factor activity protein binding nucleus nuclear envelope nucleoplasm nucleoplasm transcription regulator complex nucleolus cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II animal organ morphogenesis sarcoplasm cell projection organization intracellular membrane-bounded organelle sequence-specific DNA binding protein dimerization activity regulation of cell cycle RNA polymerase II transcription regulator complex	04110 04350
1416301_a_at	Ebf1	early B cell factor 1	11	44618099, 44620227	BB125261	13591	257	RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II multicellular organism development positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II metal ion binding C2H2 zinc finger domain binding
1423571_at	S1pr1	sphingosine-1-phosphate receptor 1	3	-115710432	BB133079	13609	288	angiogenesis angiogenesis G protein-coupled receptor binding blood vessel maturation cardiac muscle tissue growth involved in heart morphogenesis sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway G protein-coupled receptor activity nucleoplasm cytoplasm endosome plasma membrane plasma membrane chemotaxis signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway brain development cell population proliferation positive regulation of cell population proliferation external side of plasma membrane membrane cell migration regulation of metabolic process lamellipodium assembly actin cytoskeleton organization regulation of cell adhesion positive regulation of cell migration regulation of bone mineralization leukocyte chemotaxis sphingosine-1-phosphate receptor activity sphingosine-1-phosphate receptor activity sphingosine-1-phosphate receptor activity intracellular membrane-bounded organelle regulation of bone resorption positive regulation of transcription by RNA polymerase II sphingolipid binding positive regulation of smooth muscle cell proliferation positive regulation of positive chemotaxis negative regulation of stress fiber assembly heart trabecula morphogenesis T cell migration	04080
1436329_at	Egr3	early growth response 3	14	70077316, 70077794	AV346607	13655	110	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific positive regulation of endothelial cell proliferation cell migration involved in sprouting angiogenesis DNA binding nucleus nucleoplasm regulation of transcription by RNA polymerase II neuromuscular synaptic transmission peripheral nervous system development positive regulation of T cell differentiation in thymus endothelial cell chemotaxis cellular response to vascular endothelial growth factor stimulus negative regulation of apoptotic process sequence-specific DNA binding cellular response to fibroblast growth factor stimulus regulation of gamma-delta T cell differentiation positive regulation of transcription by RNA polymerase II metal ion binding sequence-specific double-stranded DNA binding
1448175_at	Ehd1	EH-domain containing 1	19	6276895	NM_010119	13660	56	nucleotide binding calcium ion binding protein binding ATP binding GTP binding cytoplasm endosome early endosome early endosome lipid droplet plasma membrane plasma membrane cilium intracellular protein transport endocytosis endocytosis endocytosis endosome membrane positive regulation of cholesterol storage positive regulation of neuron projection development protein transport membrane endosomal transport ciliary pocket membrane cell projection organization endocytic vesicle endocytic vesicle platelet dense tubular network membrane neuron projection development small GTPase binding cytoplasmic vesicle early endosome membrane endocytic recycling endocytic recycling low-density lipoprotein particle clearance cholesterol homeostasis identical protein binding cell projection myelin sheath metal ion binding perinuclear region of cytoplasm perinuclear region of cytoplasm protein homooligomerization recycling endosome membrane recycling endosome membrane cilium assembly cilium assembly cilium assembly protein localization to cilium protein localization to plasma membrane positive regulation of myoblast fusion cellular response to nerve growth factor stimulus positive regulation of endocytic recycling	04144
1449278_at	Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	6	70844514, 70844514	NM_010121	13666	287	nucleotide binding skeletal system development ossification angiogenesis chondrocyte development protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity eukaryotic translation initiation factor 2alpha kinase activity eukaryotic translation initiation factor 2alpha kinase activity eukaryotic translation initiation factor 2alpha kinase activity eukaryotic translation initiation factor 2alpha kinase activity eukaryotic translation initiation factor 2alpha kinase activity protein binding ATP binding nucleus cytoplasm cytoplasm endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane translation regulation of translation regulation of translational initiation protein phosphorylation protein phosphorylation activation of cysteine-type endopeptidase activity involved in apoptotic process ER overload response response to unfolded protein endoplasmic reticulum organization lactation positive regulation of signal transduction positive regulation of vascular endothelial growth factor production positive regulation of vascular endothelial growth factor production positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression regulation of translational initiation by eIF2 alpha phosphorylation regulation of translational initiation by eIF2 alpha phosphorylation membrane kinase activity phosphorylation transferase activity negative regulation of translation negative regulation of translation negative regulation of translation negative regulation of translation peptidyl-serine phosphorylation regulation of fatty acid metabolic process calcium-mediated signaling enzyme binding protein phosphatase binding bone mineralization endoplasmic reticulum unfolded protein response endoplasmic reticulum unfolded protein response endoplasmic reticulum unfolded protein response endoplasmic reticulum unfolded protein response pancreas development endocrine pancreas development negative regulation of myelination negative regulation of translation in response to stress positive regulation of protein binding SREBP signaling pathway cellular response to amino acid starvation response to endoplasmic reticulum stress response to endoplasmic reticulum stress response to endoplasmic reticulum stress eiF2alpha phosphorylation in response to endoplasmic reticulum stress eiF2alpha phosphorylation in response to endoplasmic reticulum stress eiF2alpha phosphorylation in response to endoplasmic reticulum stress PERK-mediated unfolded protein response cellular response to glucose starvation cellular response to glucose starvation identical protein binding identical protein binding negative regulation of apoptotic process endoplasmic reticulum quality control compartment fat cell differentiation positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase I protein autophosphorylation protein autophosphorylation protein autophosphorylation insulin-like growth factor receptor signaling pathway perinuclear region of cytoplasm Hsp90 protein binding regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress cellular response to cold eukaryotic initiation factor eIF2 binding positive regulation of protein localization to nucleus negative regulation of translation in response to endoplasmic reticulum stress regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway positive regulation of glutathione biosynthetic process positive regulation of ERAD pathway	04141 05010 05160
1450934_at	Eif4a2	eukaryotic translation initiation factor 4A2	16	23107467	BM240314	13682	48	nucleotide binding cytoplasmic translational initiation nucleic acid binding RNA binding RNA helicase activity translation initiation factor activity translation initiation factor activity helicase activity ATP binding translation translational initiation eukaryotic translation initiation factor 4F complex hydrolase activity ATP hydrolysis activity perinuclear region of cytoplasm negative regulation of RNA-dependent RNA polymerase activity cellular response to leukemia inhibitory factor	03013
1427162_a_at	Elk4	ELK4, member of ETS oncogene family	1	132007619, 132008101, 132008344	AW146130	13714	45	negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding chromatin binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm cytosol regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cell differentiation sequence-specific DNA binding positive regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding	04010
1451161_a_at	Adgre1	adhesion G protein-coupled receptor E1	17	57358685	U66888	13733	274	adaptive immune response immune system process transmembrane signaling receptor activity G protein-coupled receptor activity G protein-coupled receptor activity calcium ion binding plasma membrane signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway external side of plasma membrane membrane cell periphery
1420965_a_at	Enc1	ectodermal-neural cortex 1	13	97241104	BM120053	13803	44	chromatin actin binding nucleus nucleoplasm cytoplasm cytoplasm cytoskeleton multicellular organism development proteasomal ubiquitin-independent protein catabolic process proteasomal ubiquitin-independent protein catabolic process positive regulation of neuron projection development nuclear matrix protein ubiquitination negative regulation of translation Cul3-RING ubiquitin ligase complex Cul3-RING ubiquitin ligase complex neuronal cell body
1417338_at	Epb42	erythrocyte membrane protein band 4.2	2	-121017890	U03487	13828	47	cell morphogenesis protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity cytoplasm cytoskeleton plasma membrane regulation of cell shape membrane peptide cross-linking peptide cross-linking hemoglobin metabolic process cortical cytoskeleton erythrocyte maturation spleen development monoatomic ion homeostasis multicellular organismal-level iron ion homeostasis ankyrin-1 complex
1418850_at	Epc1	enhancer of polycomb homolog 1	18	-6488891, -6435950, -6435950	NM_007935	13831	39	negative regulation of transcription by RNA polymerase II double-strand break repair via homologous recombination nucleosome nucleus nucleus nucleoplasm nucleolus cytoplasm chromatin organization regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II spermatogenesis spermatid development nuclear body cell differentiation nuclear membrane piccolo histone acetyltransferase complex piccolo histone acetyltransferase complex sperm DNA condensation NuA4 histone acetyltransferase complex site of double-strand break regulation of apoptotic process negative regulation of gene expression, epigenetic negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of striated muscle cell differentiation regulation of cell cycle chromatin-protein adaptor activity enzyme-substrate adaptor activity regulation of chromatin organization positive regulation of double-strand break repair via homologous recombination regulation of double-strand break repair
1422438_at	Ephx1	epoxide hydrolase 1, microsomal	1	-180989555	NM_010145	13849	55	catalytic activity epoxide hydrolase activity epoxide hydrolase activity endoplasmic reticulum lipid metabolic process cellular aromatic compound metabolic process oxysterol binding response to toxic substance response to organic cyclic compound membrane hydrolase activity ether hydrolase activity arachidonic acid metabolic process arachidonic acid metabolic process aromatic compound catabolic process enzyme binding cis-stilbene-oxide hydrolase activity diol biosynthetic process intracellular membrane-bounded organelle epoxide metabolic process epoxide metabolic process	00980 04976
1419406_a_at	Bcl11a	BCL11 transcription factor A	11	24080694, 24078055, 24078055	NM_016707	14025	86	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding transcription regulatory region nucleic acid binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription factor activity transcription coregulator activity transcription corepressor activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm regulation of transcription by RNA polymerase II gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of neuron projection development negative regulation of neuron projection development SWI/SNF complex SWI/SNF complex nuclear body protein sumoylation protein kinase binding B cell differentiation T cell differentiation paraspeckles protein homodimerization activity metal ion binding protein heterodimerization activity negative regulation of collateral sprouting positive regulation of collateral sprouting regulation of dendrite development postsynapse DNA-binding transcription factor binding negative regulation of dendrite extension negative regulation of neuron remodeling negative regulation of dendrite development negative regulation of dendrite development negative regulation of branching morphogenesis of a nerve
1434920_a_at	Evl	Ena-vasodilator stimulated phosphoprotein	12	108605765, 108635752, 108554719	AW553781	14026	50	actin binding protein binding profilin binding profilin binding cytoplasm cytoskeleton focal adhesion axon guidance actin polymerization or depolymerization actin polymerization or depolymerization negative regulation of epithelial cell migration SH3 domain binding SH3 domain binding lamellipodium actin filament-based movement platelet activation positive regulation of actin filament polymerization positive regulation of actin filament polymerization cell projection actin nucleation phagocytic vesicle barbed-end actin filament capping protein homotetramerization positive regulation of stress fiber assembly cellular response to type II interferon negative regulation of ruffle assembly
1436884_x_at	Ewsr1	Ewing sarcoma breakpoint region 1	11	-5069686, -5080077	BB699868	14030	101	nucleic acid binding transcription coregulator activity RNA binding RNA binding protein binding calmodulin binding nucleus nucleus nucleoplasm nucleolus cytoplasm plasma membrane regulation of DNA-templated transcription Cajal body membrane identical protein binding metal ion binding
1417160_s_at	Wfdc18	WAP four-disulfide core domain 18	11	83709003	NM_007969	14038	20	serine-type endopeptidase inhibitor activity extracellular region extracellular space negative regulation of peptidase activity antibacterial humoral response peptidase inhibitor activity innate immune response
1435203_at	Man2a2	mannosidase 2, alpha 2	7	-80349096	BB794673	140481	23	Golgi membrane catalytic activity alpha-mannosidase activity alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity Golgi apparatus carbohydrate metabolic process mannose metabolic process N-glycan processing protein deglycosylation metabolic process mannosidase activity membrane hydrolase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding metal ion binding	00510 01100
1449305_at	F10	coagulation factor X	8	13037307	NM_007972	14058	53	serine-type endopeptidase activity calcium ion binding phospholipid binding extracellular region extracellular space proteolysis blood coagulation hemostasis peptidase activity serine-type peptidase activity hydrolase activity positive regulation of TOR signaling	04610
1418897_at	F2	coagulation factor II	2	-91625319	NM_010168	14061	97	lipopolysaccharide binding positive regulation of protein phosphorylation endopeptidase activity serine-type endopeptidase activity serine-type endopeptidase activity serine-type endopeptidase activity signaling receptor binding calcium ion binding protein binding extracellular region extracellular space extracellular space proteolysis acute-phase response cell surface receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway blood coagulation hemostasis heparin binding peptidase activity serine-type peptidase activity positive regulation of cell population proliferation regulation of cell shape response to wounding external side of plasma membrane regulation of gene expression hydrolase activity platelet activation platelet activation platelet activation positive regulation of blood coagulation positive regulation of blood coagulation positive regulation of cell growth positive regulation of insulin secretion positive regulation of insulin secretion positive regulation of collagen biosynthetic process fibrinolysis negative regulation of proteolysis negative regulation of astrocyte differentiation positive regulation of release of sequestered calcium ion into cytosol regulation of cytosolic calcium ion concentration cytolysis by host of symbiont cells positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction antimicrobial humoral immune response mediated by antimicrobial peptide collagen-containing extracellular matrix collagen-containing extracellular matrix collagen-containing extracellular matrix thrombospondin receptor activity thrombin-activated receptor signaling pathway neutrophil-mediated killing of gram-negative bacterium positive regulation of lipid kinase activity negative regulation of cytokine production involved in inflammatory response positive regulation of protein localization to nucleus positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway ligand-gated ion channel signaling pathway ligand-gated ion channel signaling pathway positive regulation of reactive oxygen species metabolic process	04080 04610 04810
1448931_at	F2rl1	F2R like trypsin receptor 1	13	-95511729	NM_007974	14063	325	proteinase-activated receptor activity G-protein alpha-subunit binding protease binding T cell activation involved in immune response immune system process positive regulation of leukocyte chemotaxis positive regulation of cytokine production involved in immune response positive regulation of glomerular filtration G protein-coupled receptor activity G protein-coupled receptor activity G protein-coupled receptor activity early endosome plasma membrane inflammatory response signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of cytosolic calcium ion concentration blood coagulation negative regulation of tumor necrosis factor-mediated signaling pathway thrombin-activated receptor activity membrane regulation of blood coagulation positive regulation of cell migration positive regulation of actin filament depolymerization pseudopodium positive regulation of pseudopodium assembly G-protein beta-subunit binding negative regulation of chemokine production positive regulation of chemokine production positive regulation of chemokine production positive regulation of type II interferon production positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production heterotrimeric G-protein binding positive regulation of superoxide anion generation positive regulation of toll-like receptor 2 signaling pathway negative regulation of toll-like receptor 3 signaling pathway positive regulation of toll-like receptor 3 signaling pathway positive regulation of toll-like receptor 4 signaling pathway positive regulation of Rho protein signal transduction positive regulation of Rho protein signal transduction positive regulation of Rho protein signal transduction neutrophil activation vasodilation vasodilation vasodilation regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of eosinophil degranulation positive regulation of GTPase activity innate immune response cell-cell junction maintenance positive regulation of transcription by RNA polymerase II regulation of JNK cascade negative regulation of JNK cascade positive regulation of JNK cascade negative regulation of insulin secretion negative regulation of insulin secretion leukocyte migration positive regulation of chemotaxis positive regulation of positive chemotaxis defense response to virus defense response to virus positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of phagocytosis, engulfment establishment of endothelial barrier positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade thrombin-activated receptor signaling pathway leukocyte proliferation positive regulation of neutrophil mediated killing of gram-negative bacterium mature conventional dendritic cell differentiation mature conventional dendritic cell differentiation potassium channel activating, G protein-coupled receptor signaling pathway potassium channel activating, G protein-coupled receptor signaling pathway positive regulation of renin secretion into blood stream regulation of chemokine (C-X-C motif) ligand 2 production	04080 05143
1454699_at	Sesn1	sestrin 1	10	41810573, 41887438	BG076140	140742	40	fibrillar center protein binding nucleus nucleoplasm cytoplasm positive regulation of macroautophagy oxidoreductase activity oxidoreductase activity, acting on peroxide as acceptor negative regulation of cell growth cellular response to amino acid starvation cellular response to glucose starvation regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GATOR2 complex leucine binding leucine binding cellular response to amino acid stimulus cellular response to leucine reactive oxygen species metabolic process cellular oxidant detoxification regulation of response to reactive oxygen species negative regulation of TORC1 signaling negative regulation of TORC1 signaling negative regulation of TORC1 signaling cellular response to leucine starvation	04115
1416514_a_at	Fscn1	fascin actin-bundling protein 1	5	142960354	NM_007984	14086	77	stress fiber ruffle ruffle podosome actin binding protein binding cytoplasm cytoplasm cytosol cytoskeleton microvillus microvillus cell-cell junction actin filament organization cell-cell junction assembly establishment or maintenance of cell polarity positive regulation of lamellipodium assembly actin cytoskeleton actin cytoskeleton cell migration cell migration cell migration lamellipodium lamellipodium lamellipodium microspike assembly actin cytoskeleton organization parallel actin filament bundle assembly filopodium filopodium filopodium dendrite growth cone growth cone growth cone protein-macromolecule adaptor activity cell projection membrane cell projection membrane regulation of microvillus assembly regulation of actin cytoskeleton organization establishment of apical/basal cell polarity cell projection myelin sheath microspike cell motility actin filament binding actin filament binding actin filament binding actin filament bundle assembly actin filament bundle assembly actin filament bundle assembly positive regulation of filopodium assembly positive regulation of filopodium assembly anchoring junction positive regulation of podosome assembly positive regulation of extracellular matrix disassembly
1421775_at	Fcer1a	Fc receptor, IgE, high affinity I, alpha polypeptide	1	-173221270	NM_010184	14125	145	positive regulation of type I hypersensitivity serotonin secretion serotonin secretion protein binding plasma membrane plasma membrane signal transduction cell surface receptor signaling pathway cell surface receptor signaling pathway cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane cell surface membrane immunoglobulin mediated immune response type I hypersensitivity peptidyl-tyrosine phosphorylation leukotriene biosynthetic process calcium-mediated signaling IgE receptor activity IgE receptor activity high-affinity IgE receptor activity high-affinity IgE receptor activity IgE binding IgE binding IgE binding IgE binding granulocyte macrophage colony-stimulating factor production interleukin-3 production positive regulation of granulocyte macrophage colony-stimulating factor production positive regulation of interleukin-3 production mast cell cytokine production positive regulation of mast cell cytokine production type 2 immune response mast cell degranulation mast cell degranulation positive regulation of mast cell degranulation eosinophil degranulation positive regulation of MAP kinase activity positive regulation of JUN kinase activity membrane raft positive regulation of peptidyl-tyrosine phosphorylation positive regulation of calcium-mediated signaling establishment of localization in cell	04664 05310
1443264_at	Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	19	-11615520	AV241486	14126	46	endosome plasma membrane plasma membrane immune response signal transduction cell surface receptor signaling pathway cell surface receptor signaling pathway protein kinase C-activating G protein-coupled receptor signaling pathway external side of plasma membrane external side of plasma membrane membrane IgE receptor activity IgE binding protein kinase binding Fc-epsilon receptor I complex Fc-epsilon receptor I complex SH2 domain binding positive regulation of mast cell degranulation membrane raft phosphoprotein binding regulation of release of sequestered calcium ion into cytosol	04664 05310
1418340_at	Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	1	-171229571	NM_010185	14127	507	positive regulation of type IIa hypersensitivity positive regulation of type III hypersensitivity positive regulation of type I hypersensitivity neutrophil activation involved in immune response neutrophil activation involved in immune response T cell differentiation involved in immune response T cell differentiation involved in immune response immune system process Fc receptor mediated stimulatory signaling pathway Fc receptor mediated stimulatory signaling pathway serotonin secretion by platelet transmembrane signaling receptor activity protein binding plasma membrane plasma membrane plasma membrane phagocytosis, engulfment signal transduction cell surface receptor signaling pathway cell surface receptor signaling pathway integrin-mediated signaling pathway external side of plasma membrane external side of plasma membrane cell surface cell surface regulation of platelet activation regulation of platelet activation membrane immunoglobulin mediated immune response immunoglobulin mediated immune response IgE receptor activity IgE receptor activity IgE receptor activity IgE binding IgE binding IgG binding IgG binding antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II osteoclast differentiation neutrophil chemotaxis neutrophil chemotaxis receptor internalization interleukin-2 production interleukin-6 production interleukin-6 production tumor necrosis factor production tumor necrosis factor production positive regulation of interleukin-10 production positive regulation of interleukin-4 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production mast cell cytokine production mast cell cytokine production positive regulation of mast cell cytokine production positive regulation of mast cell cytokine production Fc-epsilon receptor I complex Fc-epsilon receptor I complex Fc-gamma receptor III complex mast cell apoptotic process mast cell apoptotic process negative regulation of mast cell apoptotic process negative regulation of mast cell apoptotic process Fc-gamma receptor signaling pathway Fc-gamma receptor signaling pathway Fc-epsilon receptor signaling pathway interleukin-3-mediated signaling pathway antigen processing and presentation of exogenous peptide antigen via MHC class I antigen processing and presentation of exogenous peptide antigen via MHC class I defense response to bacterium defense response to bacterium identical protein binding identical protein binding protein homodimerization activity mast cell degranulation mast cell degranulation positive regulation of mast cell degranulation positive regulation of mast cell degranulation innate immune response innate immune response membrane raft mast cell activation mast cell activation metal ion binding protein heterodimerization activity positive regulation of phagocytosis positive regulation of phagocytosis regulation of immune response positive regulation of immune response cellular response to low-density lipoprotein particle stimulus protein localization to plasma membrane positive regulation of protein localization to cell surface positive regulation of protein localization to cell surface	04650 04664 05310
1422122_at	Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	8	-3681736, -3681736, -3681736	M99371	14128	91	B cell antigen processing and presentation positive regulation of humoral immune response mediated by circulating immunoglobulin plasma membrane immune response external side of plasma membrane external side of plasma membrane membrane low-affinity IgE receptor activity IgE binding carbohydrate binding carbohydrate binding macrophage activation biological process involved in interspecies interaction between organisms metal ion binding positive regulation of nitric-oxide synthase activity positive regulation of killing of cells of another organism positive regulation of nitric-oxide synthase biosynthetic process Fc receptor-mediated immune complex endocytosis	04640
1417876_at	Fcgr1	Fc receptor, IgG, high affinity I	3	-96282908	AF143181	14129	204	antibody-dependent cellular cytotoxicity antibody-dependent cellular cytotoxicity positive regulation of type IIa hypersensitivity positive regulation of type III hypersensitivity immune system process plasma membrane receptor-mediated endocytosis phagocytosis, recognition phagocytosis, engulfment cell surface receptor signaling pathway cell surface receptor signaling pathway response to bacterium external side of plasma membrane external side of plasma membrane membrane IgG receptor activity IgG receptor activity high-affinity IgG receptor activity IgG binding IgG binding antigen processing and presentation of exogenous antigen leukotriene receptor binding antigen processing and presentation of exogenous peptide antigen via MHC class I defense response to bacterium innate immune response positive regulation of phagocytosis regulation of immune response positive regulation of phagocytosis, engulfment	04145 04380 04640 04666 05140 05150 05322
1451941_a_at	Fcgr2b	Fc receptor, IgG, low affinity IIb	1	-170960558	M14216	14130	504	amyloid-beta binding antibody-dependent cellular cytotoxicity negative regulation of type I hypersensitivity immunoglobulin production immune complex clearance negative regulation of immunoglobulin production negative regulation of inflammatory response to antigenic stimulus negative regulation of acute inflammatory response to antigenic stimulus negative regulation of humoral immune response mediated by circulating immunoglobulin protein binding extracellular region cytoplasm cytoskeleton plasma membrane plasma membrane plasma membrane receptor-mediated endocytosis phagocytosis phagocytosis, engulfment defense response cell surface receptor signaling pathway cell surface receptor signaling pathway response to bacterium external side of plasma membrane external side of plasma membrane cell surface membrane immunoglobulin mediated immune response dendrite development IgG receptor activity low-affinity IgG receptor activity IgG binding IgG binding IgG binding immunoglobulin binding antigen processing and presentation of exogenous peptide antigen via MHC class II cerebellum development negative regulation of B cell proliferation endocytic recycling interleukin-10 production negative regulation of interleukin-10 production positive regulation of tumor necrosis factor production negative regulation of neutrophil apoptotic process B cell proliferation dendritic spine cell body protein-containing complex binding positive regulation of JNK cascade regulation of long-term neuronal synaptic plasticity negative regulation of phagocytosis positive regulation of phagocytosis positive regulation of phagocytosis negative regulation of immune response positive regulation of DNA-binding transcription factor activity establishment of localization in cell recycling endosome cellular response to molecule of bacterial origin Fc receptor-mediated immune complex endocytosis regulation of dendritic spine maintenance regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway cellular response to amyloid-beta cellular response to amyloid-beta positive regulation of response to endoplasmic reticulum stress positive regulation of response to endoplasmic reticulum stress	04145 04380 04662 04666 05150 05322
1448620_at	Fcgr3	Fc receptor, IgG, low affinity III	1	-171051168, -171051168	NM_010188	14131	254	antibody-dependent cellular cytotoxicity antibody-dependent cellular cytotoxicity positive regulation of type IIa hypersensitivity positive regulation of type III hypersensitivity positive regulation of type I hypersensitivity positive regulation of type I hypersensitivity serotonin secretion plasma membrane phagocytosis, recognition phagocytosis, engulfment cell surface receptor signaling pathway cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane cell surface cell surface membrane IgG receptor activity IgG receptor activity IgG receptor activity IgG binding IgG binding neutrophil chemotaxis positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production immunoglobulin receptor binding antigen processing and presentation of exogenous peptide antigen via MHC class I mast cell activation mast cell activation positive regulation of phagocytosis positive regulation of phagocytosis regulation of immune response	04145 04380 04650 05140 05150 05322
1418497_at	Fgf13	fibroblast growth factor 13	X	-59062145, -59062145, -59062145, -59062145	AF020737	14168	65	MAPK cascade neuron migration nucleus nucleus nucleus cytoplasm cytoplasm cytoplasm cytosol cytosol microtubule plasma membrane sodium ion transport negative regulation of microtubule depolymerization nervous system development learning or memory learning memory microtubule binding growth factor activity intercalated disc membrane lateral plasma membrane sodium channel regulator activity sodium channel regulator activity sodium channel regulator activity hippocampus development cerebral cortex cell migration neurogenesis filopodium protein kinase activator activity axon dendrite growth cone cell projection neuron projection transmembrane transporter binding establishment of neuroblast polarity microtubule polymerization beta-tubulin binding negative regulation of collateral sprouting branching morphogenesis of a nerve protein localization to plasma membrane regulation of cardiac muscle cell action potential involved in regulation of contraction inhibitory synapse assembly regulation of voltage-gated sodium channel activity positive regulation of voltage-gated sodium channel activity	04010 04810 05200 05218
1442804_at	Fgr	FGR proto-oncogene, Src family tyrosine kinase	4	132974094	BB165085	14191	113	nucleotide binding phosphotyrosine residue binding phosphotyrosine residue binding positive regulation of cytokine production immune system process protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity signaling receptor binding protein binding ATP binding cytoplasm mitochondrion mitochondrial inner membrane cytoskeleton plasma membrane plasma membrane protein phosphorylation protein phosphorylation transmembrane receptor protein tyrosine kinase signaling pathway integrin-mediated signaling pathway integrin-mediated signaling pathway integrin-mediated signaling pathway regulation of cell shape actin cytoskeleton membrane aggresome kinase activity phosphorylation transferase activity peptidyl-tyrosine phosphorylation peptidyl-tyrosine phosphorylation protein kinase binding protein kinase binding cell differentiation bone mineralization positive regulation of cell migration ruffle membrane negative regulation of natural killer cell activation regulation of actin cytoskeleton organization immunoglobulin receptor binding Fc-gamma receptor I complex binding cell projection positive regulation of mast cell degranulation innate immune response innate immune response regulation of innate immune response regulation of protein kinase activity protein autophosphorylation skeletal system morphogenesis regulation of phagocytosis defense response to Gram-positive bacterium defense response to Gram-positive bacterium positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	04062
1424828_a_at	Fh1	fumarate hydratase 1	1	-175601377	BC006048	14194	58	urea cycle regulation of arginine metabolic process catalytic activity fumarate hydratase activity fumarate hydratase activity fumarate hydratase activity nucleus chromosome cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial matrix cytosol tricarboxylic acid cycle tricarboxylic acid cycle tricarboxylic acid cycle fumarate metabolic process fumarate metabolic process fumarate metabolic process malate metabolic process malate metabolic process DNA repair DNA damage response lyase activity site of double-strand break histone binding tricarboxylic acid cycle enzyme complex homeostasis of number of cells within a tissue positive regulation of cold-induced thermogenesis positive regulation of double-strand break repair via nonhomologous end joining	00020 01100 05200 05211
1416125_at	Fkbp5	FK506 binding protein 5	17	-28398752	U16959	14229	134	protein peptidyl-prolyl isomerization peptidyl-prolyl cis-trans isomerase activity peptidyl-prolyl cis-trans isomerase activity protein binding nucleus nucleoplasm cytoplasm cytoplasm cytosol response to bacterium isomerase activity heat shock protein binding chaperone-mediated protein folding chaperone-mediated protein folding
1418288_at	Lpin1	lipin 1	12	-16535668, -16535668	NM_015763	14245	138	negative regulation of transcription by RNA polymerase II mitochondrial fission transcription coactivator activity transcription coactivator activity protein binding nucleus nucleus transcription regulator complex cytoplasm mitochondrion mitochondrial outer membrane mitochondrial outer membrane endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane cytosol lipid metabolic process triglyceride mobilization immune response phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity phosphatidate phosphatase activity fatty acid catabolic process fatty acid catabolic process membrane hydrolase activity triglyceride biosynthetic process triglyceride biosynthetic process triglyceride biosynthetic process actin cytoskeleton organization ruffle organization negative regulation of myelination nuclear membrane cellular response to insulin stimulus cellular response to insulin stimulus cellular response to insulin stimulus histone deacetylase binding peroxisome proliferator activated receptor binding cellular lipid metabolic process fat cell differentiation regulation of fat cell differentiation positive regulation of DNA replication positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II phosphatidic acid metabolic process RNA polymerase II-specific DNA-binding transcription factor binding positive regulation of cold-induced thermogenesis
1448559_at	Flot1	flotillin 1	17	35823356	NM_008027	14251	66	positive regulation of cytokine production uropod positive regulation of protein phosphorylation protease binding regulation of receptor internalization regulation of receptor internalization regulation of receptor internalization protein binding endosome early endosome microtubule organizing center plasma membrane plasma membrane plasma membrane caveola caveola cell-cell junction adherens junction endocytosis axonogenesis axon guidance COP9 signalosome external side of plasma membrane membrane basolateral plasma membrane flotillin complex flotillin complex flotillin complex extracellular matrix disassembly lamellipodium cortical actin cytoskeleton cytoplasmic vesicle cytoplasmic vesicle positive regulation of protein binding positive regulation of protein binding positive regulation of synaptic transmission, dopaminergic positive regulation of interferon-beta production dsRNA transport positive regulation of heterotypic cell-cell adhesion positive regulation of toll-like receptor 3 signaling pathway centriolar satellite response to endoplasmic reticulum stress regulation of Rho protein signal transduction ionotropic glutamate receptor binding sarcolemma positive regulation of canonical NF-kappaB signal transduction cell-cell contact zone plasma membrane raft plasma membrane raft assembly plasma membrane raft organization membrane raft membrane raft synapse positive regulation of endocytosis positive regulation of endocytosis positive regulation of endocytosis positive regulation of skeletal muscle tissue development positive regulation of skeletal muscle tissue development presynaptic active zone protein stabilization regulation of neurotransmitter uptake protein kinase C signaling protein kinase C signaling protein kinase C signaling cellular response to exogenous dsRNA protein localization to plasma membrane protein localization to plasma membrane protein localization to plasma membrane dopaminergic synapse presynapse glutamatergic synapse GABA-ergic synapse positive regulation of myoblast fusion positive regulation of myoblast fusion positive regulation of cell junction assembly positive regulation of cell junction assembly positive regulation of cell junction assembly positive regulation of cell-cell adhesion mediated by cadherin positive regulation of cell-cell adhesion mediated by cadherin positive regulation of cell-cell adhesion mediated by cadherin	04910
1438164_x_at	Flot2	flotillin 2	11	78037930	BB118974	14252	60	uropod protease binding acrosomal membrane endosome plasma membrane plasma membrane caveola caveola adherens junction cell adhesion negative regulation of gene expression membrane basolateral plasma membrane flotillin complex flotillin complex flotillin complex lamellipodium endocytic vesicle cortical actin cytoskeleton cytoplasmic vesicle cytoplasmic vesicle cytoplasmic vesicle vesicle ionotropic glutamate receptor binding positive regulation of canonical NF-kappaB signal transduction intracellular membrane-bounded organelle cell-cell contact zone protein localization to plasma membrane raft membrane raft synapse regulation of myoblast differentiation regulation of myoblast differentiation perinuclear region of cytoplasm presynaptic active zone membrane protein stabilization protein localization to plasma membrane protein localization to plasma membrane anterograde dendritic transport anterograde dendritic transport glutamatergic synapse glutamatergic synapse glutamatergic synapse regulation of postsynaptic membrane neurotransmitter receptor levels regulation of postsynaptic membrane neurotransmitter receptor levels negative regulation of amyloid precursor protein catabolic process positive regulation of establishment of T cell polarity	04910
1437247_at	Fosl2	fos-like antigen 2	5	32136471	BM245170	14284	72	cell morphogenesis transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific ossification osteoblast differentiation response to hypoxia response to hypoxia cytokine production cytokine production NK T cell differentiation chondrocyte differentiation inflammatory response to antigenic stimulus keratinocyte development growth plate cartilage development DNA binding chromatin binding double-stranded DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II inflammatory response inflammatory response response to xenobiotic stimulus gene expression gene expression B cell differentiation T cell differentiation neutrophil differentiation macrophage differentiation macrophage differentiation bone mineralization osteoclast differentiation lung development response to estradiol response to lipopolysaccharide chemokine production granulocyte macrophage colony-stimulating factor production interleukin-2 production interleukin-4 production collagen metabolic process collagen biosynthetic process multicellular organism growth T-helper 2 cell cytokine production response to interleukin-13 chondrocyte proliferation myofibroblast differentiation regulation of multicellular organism growth regulation of multicellular organism growth B cell proliferation glucose homeostasis sequence-specific DNA binding innate immune response fat cell differentiation positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of fibroblast proliferation lung alveolus development smooth muscle tissue development tissue remodeling homeostasis of number of cells homeostasis of number of cells within a tissue homeostasis of number of cells within a tissue T cell receptor signaling pathway T cell receptor signaling pathway cartilage development response to glucocorticoid bone development bone development lung connective tissue development fat pad development alveolar secondary septum development mucus secretion chemokine (C-C motif) ligand 11 production RNA polymerase II transcription regulator complex response to interleukin-7 response to Gram-positive bacterium insulin metabolic process fat cell apoptotic process regulation of myofibroblast differentiation regulation of myofibroblast differentiation response to bleomycin response to leukemia inhibitory factor	04380
1422953_at	Fpr2	formyl peptide receptor 2	17	17887823	NM_008039	14289	126	amyloid-beta binding amyloid-beta binding positive regulation of protein phosphorylation complement receptor mediated signaling pathway immune response-regulating cell surface receptor signaling pathway complement receptor activity G protein-coupled receptor activity N-formyl peptide receptor activity N-formyl peptide receptor activity scavenger receptor binding cytoplasm plasma membrane plasma membrane chemotaxis inflammatory response signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration membrane calcium-mediated signaling positive regulation of superoxide anion generation signaling receptor activity signaling receptor activity defense response to bacterium positive regulation of innate immune response negative regulation of inflammatory response positive regulation of phagocytosis RAGE receptor binding positive chemotaxis positive regulation of ERK1 and ERK2 cascade positive regulation of monocyte chemotaxis cellular response to amyloid-beta cellular response to amyloid-beta	04080 05150
1450808_at	Fpr1	formyl peptide receptor 1	17	-17876470	NM_013521	14293	88	G protein-coupled receptor binding complement receptor mediated signaling pathway complement receptor activity G protein-coupled receptor activity N-formyl peptide receptor activity N-formyl peptide receptor activity N-formyl peptide receptor activity scavenger receptor binding cytoplasm plasma membrane plasma membrane chemotaxis inflammatory response signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration membrane RAGE receptor binding	04080 05150
1425822_a_at	Dtx1	deltex 1, E3 ubiquitin ligase	5	-120680263	AB015422	14357	44	Notch binding protein binding nucleus nucleoplasm nucleoplasm cytoplasm cytosol cytosol Notch signaling pathway Notch signaling pathway Notch signaling pathway zinc ion binding regulation of Notch signaling pathway glial cell differentiation protein ubiquitination protein ubiquitination nuclear body transferase activity SH3 domain binding T cell differentiation ubiquitin protein ligase binding negative regulation of T cell differentiation negative regulation of neuron differentiation metal ion binding ubiquitin protein ligase activity cellular response to leukemia inhibitory factor	04330
1448700_at	G0s2	G0/G1 switch gene 2	1	-193272159	NM_008059	14373	36	mitochondrion mitochondrion apoptotic process extrinsic apoptotic signaling pathway positive regulation of cold-induced thermogenesis positive regulation of extrinsic apoptotic signaling pathway positive regulation of extrinsic apoptotic signaling pathway
1448354_at	G6pdx	glucose-6-phosphate dehydrogenase X-linked	X	-74409482	NM_008062	14381	146	cytokine production angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure glucose-6-phosphate dehydrogenase activity glucose-6-phosphate dehydrogenase activity glucose-6-phosphate dehydrogenase activity glucose-6-phosphate dehydrogenase activity glucose binding cytoplasm cytosol cytosol cytosol carbohydrate metabolic process glucose metabolic process glucose metabolic process pentose-phosphate shunt cholesterol biosynthetic process NADP metabolic process NADPH regeneration NADP biosynthetic process NADP biosynthetic process glutathione metabolic process glutathione metabolic process response to oxidative stress pentose-phosphate shunt, oxidative branch pentose-phosphate shunt, oxidative branch pentose-phosphate shunt, oxidative branch cytoplasmic side of plasma membrane negative regulation of protein glutathionylation membrane oxidoreductase activity oxidoreductase activity, acting on CH-OH group of donors pentose biosynthetic process pentose biosynthetic process pentose biosynthetic process carbohydrate binding interleukin-10 production interleukin-12 production centriolar satellite cellular response to oxidative stress regulation of multicellular organism growth identical protein binding identical protein binding protein homodimerization activity intracellular membrane-bounded organelle erythrocyte maturation regulation of neuron apoptotic process response to ethanol ribose phosphate biosynthetic process erythrocyte development NADP binding glucose 6-phosphate metabolic process negative regulation of cell growth involved in cardiac muscle cell development positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel negative regulation of reactive oxygen species metabolic process	00030 00480 01100
1417694_at	Gab1	growth factor receptor bound protein 2-associated protein 1	8	-80764433, -80764430	NM_021356	14388	107	MAPK cascade angiogenesis protein binding cytoplasm cytoplasm cytosol cell-cell junction cell cortex response to oxidative stress signal transduction signal transduction epidermal growth factor receptor signaling pathway heart development epidermis development regulation of cell migration signaling adaptor activity signaling adaptor activity signaling adaptor activity response to hepatocyte growth factor cellular response to vascular endothelial growth factor stimulus vascular endothelial growth factor signaling pathway positive regulation of cell migration by vascular endothelial growth factor signaling pathway positive regulation of MAP kinase activity positive regulation of MAPK cascade positive regulation of MAPK cascade positive regulation of angiogenesis platelet-derived growth factor receptor signaling pathway labyrinthine layer development interleukin-6-mediated signaling pathway endothelial cell chemotaxis to vascular endothelial growth factor	04012 04722 05100 05211
1418655_at	B4galnt1	beta-1,4-N-acetyl-galactosaminyl transferase 1	10	127165155, 127165830, 127165830, 127165155	U18975	14421	105	Golgi membrane ganglioside biosynthetic process ganglioside biosynthetic process ganglioside biosynthetic process ganglioside biosynthetic process (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity Golgi apparatus lipid metabolic process sphingolipid metabolic process glycosphingolipid metabolic process glycosphingolipid metabolic process glycosphingolipid biosynthetic process vacuole organization spermatogenesis determination of adult lifespan acetylgalactosaminyltransferase activity acetylgalactosaminyltransferase activity membrane transferase activity glycosyltransferase activity hexosyltransferase activity lipid storage nerve development lipid glycosylation limb development motor behavior	00604 01100
1436222_at	Gas5	growth arrest specific 5	1	161035165, 161034600	AW547050	14455	83	molecular_function cellular_component response to bacterium
1448886_at	Gata3	GATA binding protein 3	2	-9857077	NM_008091	14462	602	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin cell morphogenesis transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding cis-regulatory region sequence-specific DNA binding transcription coactivator binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific in utero embryonic development cell fate determination neuron migration cell activation regulation of cytokine production positive regulation of cytokine production kidney development mesonephros development lens development in camera-type eye immune system process immune system development pro-T cell differentiation aortic valve morphogenesis cardiac right ventricle morphogenesis ventricular septum development DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity interleukin-2 receptor binding protein binding nucleus nucleus nucleoplasm chromatin remodeling chromatin remodeling regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II inflammatory response humoral immune response signal transduction nervous system development axon guidance zinc ion binding cell population proliferation negative regulation of cell population proliferation male gonad development post-embryonic development positive regulation of signal transduction gene expression positive regulation of endothelial cell migration positive regulation of gene expression negative regulation of gene expression negative regulation of epithelial to mesenchymal transition regulation of neuron projection development neuron differentiation T cell differentiation T cell differentiation erythrocyte differentiation macrophage differentiation regulation of epithelial cell differentiation TOR signaling type II interferon production interleukin-13 production interleukin-4 production interleukin-4 production interleukin-5 production negative regulation of type II interferon production negative regulation of type II interferon production negative regulation of interleukin-2 production positive regulation of interleukin-13 production positive regulation of interleukin-13 production positive regulation of interleukin-4 production positive regulation of interleukin-4 production positive regulation of interleukin-5 production positive regulation of interleukin-5 production T cell differentiation in thymus T cell differentiation in thymus negative regulation of mammary gland epithelial cell proliferation embryonic hemopoiesis embryonic hemopoiesis ureter maturation parathyroid hormone secretion norepinephrine biosynthetic process inner ear morphogenesis identical protein binding phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of neuron apoptotic process sequence-specific DNA binding sequence-specific DNA binding ear development thymic T cell selection T-helper 2 cell differentiation T-helper 2 cell differentiation innate immune response cell fate commitment positive regulation of T cell differentiation positive regulation of cell differentiation regulation of T-helper cell differentiation negative regulation of cell cycle negative regulation of cell cycle negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding cell maturation sympathetic nervous system development thymus development embryonic organ development embryonic organ development developmental growth anatomical structure formation involved in morphogenesis homeostasis of number of cells negative regulation of inflammatory response T cell receptor signaling pathway cartilage development positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction parathyroid gland development pharyngeal system development uterus development mesenchymal to epithelial transition mast cell differentiation ureteric bud formation RNA polymerase II-specific DNA-binding transcription factor binding E-box binding cellular response to cytokine stimulus cellular response to interleukin-4 cellular response to interleukin-4 otic vesicle development cellular response to BMP stimulus HMG box domain binding positive regulation of ureteric bud formation nephric duct morphogenesis nephric duct formation regulation of nephron tubule epithelial cell differentiation ureter morphogenesis lymphocyte migration negative regulation of DNA demethylation negative regulation of DNA demethylation positive regulation of miRNA transcription histone methyltransferase binding sequence-specific double-stranded DNA binding regulation of establishment of cell polarity negative regulation of cell motility negative regulation of endothelial cell apoptotic process positive regulation of T-helper 2 cell cytokine production negative regulation of cell proliferation involved in mesonephros development positive regulation of thyroid hormone generation positive regulation of transcription regulatory region DNA binding positive regulation of transcription regulatory region DNA binding regulation of cellular response to X-ray negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation
1420549_at	Gbp2b	guanylate binding protein 2b	3	142594846	NM_010259	14468	45	Golgi membrane nucleotide binding activation of innate immune response immune system process actin binding GTPase activity GTPase activity GTPase activity G protein activity GDP phosphatase activity endopeptidase inhibitor activity protein binding GTP binding GTP binding extracellular region nucleus nucleoplasm cytoplasm Golgi apparatus cytosol plasma membrane vesicle membrane actin cytoskeleton membrane hydrolase activity GMP binding GDP binding enzyme binding cytokine binding symbiont-containing vacuole membrane spectrin binding cytoplasmic vesicle cytoplasmic vesicle cytoplasmic vesicle cellular response to interferon-beta defense response to bacterium identical protein binding protein homodimerization activity defense response to protozoan defense response to protozoan adhesion of symbiont to host innate immune response perinuclear region of cytoplasm defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to virus cytolysis in another organism Hsp90 protein binding cellular response to lipopolysaccharide cellular response to type II interferon cellular response to type II interferon symbiont cell surface positive regulation of pyroptosis molecular function inhibitor activity
1435906_x_at	Gbp2	guanylate binding protein 2	3	142620662	BE197524	14469	65	Golgi membrane nucleotide binding activation of innate immune response immune system process actin binding GTPase activity GTPase activity GTPase activity G protein activity G protein activity GDP phosphatase activity endopeptidase inhibitor activity GTP binding GTP binding nucleus nucleoplasm cytoplasm Golgi apparatus cytosol protein targeting response to bacterium vesicle membrane actin cytoskeleton membrane hydrolase activity GDP binding enzyme binding cytokine binding symbiont-containing vacuole membrane spectrin binding GTPase regulator activity cytoplasmic vesicle cytoplasmic vesicle cytoplasmic vesicle cellular response to interferon-beta defense response to bacterium defense response to bacterium identical protein binding protein homodimerization activity defense response to protozoan defense response to protozoan adhesion of symbiont to host innate immune response perinuclear region of cytoplasm defense response to Gram-positive bacterium defense response to Gram-positive bacterium cytolysis in another organism cytolysis in another organism Hsp90 protein binding cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to type II interferon cellular response to type II interferon symbiont cell surface symbiont cell surface positive regulation of pyroptosis positive regulation of pyroptosis molecular function inhibitor activity positive regulation of AIM2 inflammasome complex assembly
1419595_a_at	Ggh	gamma-glutamyl hydrolase	4	20042051	NM_010281	14590	21	extracellular region extracellular space extracellular space lysosome vacuole peptidase activity omega peptidase activity response to xenobiotic stimulus response to zinc ion hydrolase activity response to insulin gamma-glutamyl-peptidase activity gamma-glutamyl-peptidase activity response to ethanol tetrahydrofolylpolyglutamate metabolic process	00790
1448485_at	Ggt1	gamma-glutamyltransferase 1	10	75573494, 75568661, 75564131, 75571559	NM_008116	14598	69	peptidyltransferase activity regulation of immune system process regulation of immune system process leukotriene-C(4) hydrolase extracellular space endoplasmic reticulum plasma membrane plasma membrane plasma membrane proteolysis glutathione metabolic process glutathione biosynthetic process glutathione catabolic process glutathione catabolic process spermatogenesis peptidase activity membrane transferase activity acyltransferase activity aminoacyltransferase activity hydrolase activity cysteine biosynthetic process peptide modification peptide modification vesicle glutathione hydrolase activity glutathione hydrolase activity perinuclear region of cytoplasm regulation of inflammatory response regulation of inflammatory response leukotriene C4 gamma-glutamyl transferase activity	00430 00460 00480 00590 01100
1417962_s_at	Ghr	growth hormone receptor	15	-3327524, -3317754, -3317754	NM_010284	14600	313	cytokine receptor activity growth hormone receptor activity growth hormone receptor activity growth hormone receptor activity protein binding extracellular region extracellular region extracellular space extracellular space nucleus cytosol cytosol plasma membrane plasma membrane plasma membrane endocytosis receptor signaling pathway via JAK-STAT lipid binding hormone-mediated signaling pathway external side of plasma membrane cell surface membrane membrane peptide hormone binding peptide hormone binding peptide hormone binding cytokine-mediated signaling pathway cytokine-mediated signaling pathway taurine metabolic process growth factor binding growth factor binding protein kinase binding protein phosphatase binding cytokine binding regulation of response to nutrient levels response to estradiol cellular response to hormone stimulus cytoplasmic ribonucleoprotein granule regulation of multicellular organism growth positive regulation of multicellular organism growth SH2 domain binding hormone metabolic process identical protein binding protein homodimerization activity neuronal cell body receptor complex positive regulation of receptor signaling pathway via JAK-STAT positive regulation of receptor signaling pathway via JAK-STAT insulin-like growth factor receptor signaling pathway positive regulation of peptidyl-tyrosine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation growth hormone receptor signaling pathway growth hormone receptor signaling pathway growth hormone receptor signaling pathway growth hormone receptor complex growth hormone receptor complex	04060 04080 04630
1426235_a_at	Glul	glutamate-ammonia ligase	1	153899928	AI391218	14645	247	nucleotide binding magnesium ion binding angiogenesis catalytic activity glutamine synthetase activity glutamine synthetase activity protein binding ATP binding cytoplasm cytoplasm mitochondrion mitochondrion endoplasmic reticulum cytosol plasma membrane glutamate metabolic process glutamine biosynthetic process glutamine biosynthetic process nitrogen compound metabolic process cell population proliferation cellular response to starvation response to glucose regulation of endothelial cell migration regulation of endothelial cell migration membrane nickel cation binding glutamate binding transferase activity ligase activity protein palmitoylation ammonia assimilation cycle protein-cysteine S-palmitoyltransferase activity manganese ion binding positive regulation of insulin secretion protein-containing complex ribosome biogenesis identical protein binding cell projection perikaryon myelin sheath myelin sheath intracellular membrane-bounded organelle axon terminus cell body dynein light chain binding metal ion binding positive regulation of epithelial cell proliferation positive regulation of synaptic transmission, glutamatergic glial cell projection regulation of sprouting angiogenesis regulation of sprouting angiogenesis regulation of protein localization to nucleolus	00250 00330 00910 01100
1421947_at	Gng12	guanine nucleotide binding protein (G protein), gamma 12	6	66896396, 66896890	NM_025278	14701	32	heterotrimeric G-protein complex heterotrimeric G-protein complex actin filament plasma membrane signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway membrane PDZ domain binding G-protein beta-subunit binding G-protein beta-subunit binding phosphate ion binding	04010 04062 04810
1428733_at	Gngt2	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2	11	95842667, 95842294, 95843244	AK010554	14710	25	heterotrimeric G-protein complex heterotrimeric G-protein complex plasma membrane signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway membrane G-protein beta-subunit binding G-protein beta-subunit binding	04062
1456887_at	Cmklr1	chemerin chemokine-like receptor 1	5	-113612354, -113612354	AW228687	14747	83	complement receptor mediated signaling pathway complement receptor activity G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane chemotaxis chemotaxis inflammatory response signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration positive regulation of macrophage chemotaxis positive regulation of macrophage chemotaxis membrane negative regulation of NF-kappaB transcription factor activity negative regulation of interleukin-12 production positive regulation of fat cell differentiation regulation of calcium-mediated signaling regulation of calcium-mediated signaling adipokinetic hormone receptor activity adipokinetic hormone binding positive regulation of cold-induced thermogenesis
1450081_x_at	Gpi1	glucose-6-phosphate isomerase 1	7	-34201326	NM_008155	14751	239	in utero embryonic development mesoderm formation positive regulation of immunoglobulin production glucose-6-phosphate isomerase activity glucose-6-phosphate isomerase activity glucose-6-phosphate isomerase activity glucose-6-phosphate isomerase activity cytokine activity protein binding extracellular region extracellular space cytoplasm cytosol cytosol plasma membrane gluconeogenesis gluconeogenesis glycolytic process glycolytic process glycolytic process growth factor activity positive regulation of endothelial cell migration isomerase activity ubiquitin protein ligase binding erythrocyte homeostasis glucose homeostasis myelin sheath negative regulation of neuron apoptotic process monosaccharide binding monosaccharide binding glucose 6-phosphate metabolic process glucose 6-phosphate metabolic process ciliary membrane glycolytic process through glucose-6-phosphate canonical glycolysis carbohydrate derivative binding carbohydrate derivative metabolic process	00010 00030 00500 00520 01100
1434848_at	Gpr27	G protein-coupled receptor 27	6	99692366	BB259283	14761	9	G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane positive regulation of insulin secretion involved in cellular response to glucose stimulus positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway
1421816_at	Gsr	glutathione reductase	8	33653237	AK019177	14782	83	glutathione-disulfide reductase (NADP) activity glutathione-disulfide reductase (NADP) activity glutathione-disulfide reductase (NADP) activity cytoplasm mitochondrion mitochondrion cytosol cytosol glutathione metabolic process glutathione metabolic process glutathione metabolic process spermatogenesis external side of plasma membrane oxidoreductase activity oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor cellular response to oxidative stress identical protein binding glutathione binding cell redox homeostasis cell redox homeostasis flavin adenine dinucleotide binding flavin adenine dinucleotide binding NADP binding cellular oxidant detoxification	00480
1448148_at	Grn	granulin	11	102430506	M86736	14824	257	trophectodermal cell proliferation blastocyst hatching astrocyte activation involved in immune response microglial cell activation involved in immune response cytokine activity protein binding extracellular region extracellular region extracellular region extracellular space extracellular space extracellular space mitochondrion lysosome lysosome lysosomal membrane endosome late endosome endoplasmic reticulum endoplasmic reticulum Golgi apparatus Golgi apparatus trans-Golgi network plasma membrane lysosome organization lysosomal transport lysosomal transport lysosomal lumen acidification embryo implantation positive regulation of cell population proliferation positive regulation of endothelial cell migration positive regulation of neuron projection development membrane positive regulation of cell migration vesicle response to estradiol locomotory exploration behavior chondrocyte proliferation negative regulation of neuron apoptotic process positive regulation of neuron apoptotic process synapse positive regulation of angiogenesis negative regulation of innate immune response synaptic vesicle endocytosis positive regulation of axon regeneration epithelial cell proliferation positive regulation of epithelial cell proliferation positive regulation of epithelial cell proliferation regulation of inflammatory response negative regulation of inflammatory response protein stabilization protein-folding chaperone binding negative regulation of hydrolase activity retina development in camera-type eye male mating behavior negative regulation of respiratory burst involved in inflammatory response positive regulation of dendritic spine development neural precursor cell proliferation glutamatergic synapse maintenance of synapse structure maintenance of synapse structure positive regulation of inflammatory response to wounding cerebellar climbing fiber to Purkinje cell synapse cerebellar climbing fiber to Purkinje cell synapse positive regulation of defense response to bacterium negative regulation of neutrophil activation positive regulation of protein folding negative regulation of microglial cell activation positive regulation of trophectodermal cell proliferation lysosomal protein catabolic process positive regulation of aspartic-type peptidase activity positive regulation of aspartic-type peptidase activity regulation of lysosome organization positive regulation of lysosome organization positive regulation of lysosome organization
1423423_at	Pdia3	protein disulfide isomerase associated 3	2	121413901	BF319868	14827	128	acrosomal vesicle adaptive immune response immune system process peptide antigen assembly with MHC class I protein complex protein disulfide isomerase activity protein disulfide isomerase activity protein binding extracellular region extracellular space endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum lumen smooth endoplasmic reticulum protein folding peptidase activity cell surface cell surface cell surface protein-disulfide reductase activity apical plasma membrane isomerase activity protein-disulfide reductase (glutathione) activity response to endoplasmic reticulum stress MHC class I protein binding identical protein binding MHC class I peptide loading complex TAP complex myelin sheath Tapasin-ERp57 complex platelet aggregation cellular response to vitamin D extrinsic apoptotic signaling pathway cellular response to interleukin-7 positive regulation of protein folding positive regulation of extrinsic apoptotic signaling pathway	04141 04612
1448330_at	Gstm1	glutathione S-transferase, mu 1	3	-108012249, -108012259	NM_010358	14862	48	glutathione transferase activity glutathione transferase activity steroid binding protein binding extracellular region cytoplasm cytosol lipid metabolic process glutathione metabolic process glutathione metabolic process nickel cation binding transferase activity enzyme binding protein kinase binding protein-containing complex xenobiotic catabolic process identical protein binding identical protein binding protein homodimerization activity myelin sheath glutathione binding intercellular bridge cellular response to xenobiotic stimulus	00480 00980 00982
1417883_at	Gstt2	glutathione S-transferase, theta 2	10	-75831844	BC012707	14872	26	glutathione transferase activity glutathione transferase activity glutathione peroxidase activity nucleus cytoplasm cytoplasm cytosol cytosol glutathione metabolic process glutathione metabolic process transferase activity cellular response to leukemia inhibitory factor	00480 00980 00982
1425628_a_at	Gtf2i	general transcription factor II I	5	-134237831, -134237831	AF043220	14886	91	DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm transcription by RNA polymerase II embryo development negative regulation of angiogenesis positive regulation of transcription by RNA polymerase II negative regulation of cytosolic calcium ion concentration RNA polymerase II-specific DNA-binding transcription factor binding	03022
1452896_at	Cfap20	cilia and flagella associated protein 20	8	-95420249	AK011217	14894	22	nucleus nucleoplasm cytoplasm centriole cytoskeleton microtubule axonemal microtubule cilium cilium protein polyglutamylation motile cilium ciliary basal body ciliary basal body cell projection cilium assembly cilium assembly regulation of cilium beat frequency involved in ciliary motility regulation of cilium beat frequency involved in ciliary motility axonemal B tubule inner sheath positive regulation of cell motility positive regulation of cell motility positive regulation of feeding behavior
1422703_at	Gk	glycerol kinase	X	-85701936	BF683028	14933	50	nucleotide binding glycerol kinase activity glycerol kinase activity glycerol kinase activity glycerol kinase activity ATP binding nucleus cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial outer membrane cytosol cytosol carbohydrate metabolic process glycerol metabolic process glycerol metabolic process glycerol metabolic process glycerol-3-phosphate metabolic process triglyceride metabolic process triglyceride metabolic process membrane kinase activity phosphorylation phosphorylation transferase activity phosphotransferase activity, alcohol group as acceptor regulation of fatty acid metabolic process triglyceride biosynthetic process histone binding glucose homeostasis response to ethanol glycerol-3-phosphate biosynthetic process glycerol-3-phosphate biosynthetic process	00561 01100 03320
1425643_at	Gypa	glycophorin A	8	80494044	M26385	14934	37	nucleoplasm cytosol plasma membrane plasma membrane external side of plasma membrane membrane identical protein binding identical protein binding regulation of response to osmotic stress ankyrin-1 complex	05144
1452431_s_at	H2-Aa	histocompatibility 2, class II antigen A, alpha	17	-34282743	AF119253	14960	123	adaptive immune response immune system process peptide antigen assembly with MHC class II protein complex antigen processing and presentation of peptide or polysaccharide antigen via MHC class II protein binding lysosome lysosomal membrane plasma membrane immune response external side of plasma membrane membrane antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding late endosome membrane response to type II interferon negative regulation of T cell proliferation peptide antigen binding peptide antigen binding MHC class II protein complex MHC class II protein complex protein-containing complex binding positive regulation of T cell differentiation antigen processing and presentation of peptide antigen positive regulation of immune response positive regulation of T cell activation	04145 04514 04612 04672 04940 05140 05145 05150 05310 05320 05322 05323 05330 05332 05416
1451721_a_at	H2-Ab1	histocompatibility 2, class II antigen A, beta 1	17	34263226	M15848	14961	868	adaptive immune response B cell affinity maturation immune system process peptide antigen assembly with MHC class II protein complex antigen processing and presentation of peptide or polysaccharide antigen via MHC class II positive regulation of antigen processing and presentation positive regulation of T-helper 1 type immune response protein binding intracellular anatomical structure lysosomal membrane early endosome multivesicular body Golgi apparatus plasma membrane immune response external side of plasma membrane cell surface toxic substance binding membrane antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding ubiquitin protein ligase binding late endosome membrane peptide antigen binding peptide antigen binding MHC class II protein complex MHC class II protein complex protein-containing complex binding positive regulation of alpha-beta T cell activation positive regulation of alpha-beta T cell activation positive regulation of alpha-beta T cell activation antigen processing and presentation of peptide antigen positive regulation of immune response positive regulation of T cell activation cellular response to type II interferon protein antigen binding	04145 04514 04612 04672 04940 05140 05145 05150 05310 05320 05322 05323 05330 05332 05416
1417314_at	Cfb	complement factor B	17	-34856373	NM_008198	14962	182	immune system process serine-type endopeptidase activity extracellular region proteolysis complement activation complement activation complement activation, alternative pathway complement activation, alternative pathway complement activation, alternative pathway peptidase activity serine-type peptidase activity response to bacterium hydrolase activity B cell proliferation innate immune response	04610 05150
1417025_at	H2-Eb1	histocompatibility 2, class II antigen E beta	17	34305866	NM_010382	14969	84	immunological synapse adaptive immune response immune system process peptide antigen assembly with MHC class II protein complex antigen processing and presentation of peptide or polysaccharide antigen via MHC class II protein binding lysosomal membrane lysosomal membrane plasma membrane immune response external side of plasma membrane cell surface membrane antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding polysaccharide binding late endosome membrane late endosome membrane MHC class II receptor activity response to type II interferon peptide antigen binding peptide antigen binding T cell receptor binding CD4 receptor binding MHC class II protein complex MHC class II protein complex MHC class II protein complex positive regulation of immune response positive regulation of T cell activation	04145 04514 04612 04640 04672 04940 05140 05145 05150 05310 05320 05322 05323 05330 05332 05416
1454987_a_at	Hsd17b8	hydroxysteroid 17-beta dehydrogenase 8	17	-34026032	AI323545	14979	32	estradiol 17-beta-dehydrogenase [NAD(P)] activity estradiol 17-beta-dehydrogenase [NAD(P)] activity estradiol 17-beta-dehydrogenase [NAD(P)] activity mitochondrion mitochondrial envelope mitochondrial matrix plasma membrane lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process steroid biosynthetic process estrogen biosynthetic process estrogen biosynthetic process androgen metabolic process estrogen metabolic process membrane oxidoreductase activity testosterone dehydrogenase (NAD+) activity protein heterotetramerization NADH binding (3R)-hydroxyacyl-CoA dehydrogenase (NAD) activity oxidoreductase complex	00140 01100
1419744_at	H2-DMb2	histocompatibility 2, class II, locus Mb2	17	34145248, 34143228	NM_010388	15000	24	MHC class II protein complex assembly peptide antigen assembly with MHC class II protein complex peptide antigen assembly with MHC class II protein complex protein binding lysosome lysosomal membrane lysosomal membrane lysosomal membrane late endosome multivesicular body endosome membrane membrane antigen processing and presentation antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding MHC class II protein complex binding late endosome membrane late endosome membrane positive regulation of T cell proliferation peptide antigen binding MHC class II protein complex MHC class II protein complex intracellular membrane-bounded organelle positive regulation of immune response positive regulation of T cell activation chaperone cofactor-dependent protein refolding positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	04145 04514 04612 04672 04940 05140 05145 05150 05310 05320 05322 05323 05330 05332 05416
1419297_at	H2-Oa	histocompatibility 2, O region alpha locus	17	34092378	NM_008206	15001	33	peptide antigen assembly with MHC class II protein complex negative regulation of antigen processing and presentation of peptide antigen via MHC class II lysosomal membrane antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding MHC class II protein complex binding late endosome membrane peptide antigen binding MHC class II protein complex MHC class II protein complex regulation of T cell differentiation positive regulation of immune response positive regulation of T cell activation	04145 04514 04612 04672 04940 05140 05145 05150 05310 05320 05322 05323 05330 05332 05416
1440837_at	H2-Ob	histocompatibility 2, O region beta locus	17	34238904	BG144448	15002	48	peptide antigen assembly with MHC class II protein complex negative regulation of antigen processing and presentation of peptide antigen via MHC class II intracellular anatomical structure lysosome lysosomal membrane antigen processing and presentation of exogenous peptide antigen via MHC class II MHC class II protein complex binding MHC class II protein complex binding late endosome membrane peptide antigen binding MHC class II protein complex MHC class II protein complex positive regulation of immune response positive regulation of T cell activation	04145 04514 04612 04672 04940 05140 05145 05150 05310 05320 05322 05323 05330 05332 05416
1421596_s_at	Ifi44l	interferon-induced protein 44 like	3	-151758736	NM_031367	15061	11	cytoplasm immune response immune response defense response to virus
1457769_at	H60a	histocompatibility 60a	10		BB822862	15101	35	positive regulation of immune response to tumor cell plasma membrane external side of plasma membrane membrane positive regulation of type II interferon production positive regulation of natural killer cell activation positive regulation of natural killer cell activation susceptibility to natural killer cell mediated cytotoxicity positive regulation of macrophage activation positive regulation of nitric oxide biosynthetic process natural killer cell lectin-like receptor binding cellular response to organic cyclic compound	04650
1455972_x_at	Hadh	hydroxyacyl-Coenzyme A dehydrogenase	3	-131233419	AV018774	15107	48	3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity 3-hydroxyacyl-CoA dehydrogenase activity protein binding nucleoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane lipid metabolic process fatty acid metabolic process fatty acid beta-oxidation fatty acid beta-oxidation response to xenobiotic stimulus response to activity oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor identical protein binding negative regulation of insulin secretion regulation of insulin secretion NAD+ binding positive regulation of cold-induced thermogenesis	00062 00071 00280 00310 00380 00650 01100
1419407_at	Hc	hemolytic complement	2	-34983328	NM_010406	15139	336	in utero embryonic development neutrophil homeostasis kidney development immune system process endopeptidase inhibitor activity extracellular region membrane attack complex extracellular space inflammatory response complement activation, alternative pathway complement activation, classical pathway positive regulation of vascular endothelial growth factor production negative regulation of macrophage chemotaxis killing of cells of another organism positive regulation of chemokine production glomerulus development innate immune response positive regulation of angiogenesis inflammatory response to wounding	04610 05020 05150 05322
1449455_at	Hck	hemopoietic cell kinase	2	153108467	NM_010407	15162	132	nucleotide binding phosphotyrosine residue binding immune system process protein kinase activity protein tyrosine kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity signaling receptor binding protein binding ATP binding nucleus cytoplasm lysosome Golgi apparatus cytosol cytosol cytoskeleton actin filament plasma membrane caveola focal adhesion protein phosphorylation protein phosphorylation exocytosis phagocytosis inflammatory response transmembrane receptor protein tyrosine kinase signaling pathway positive regulation of cell population proliferation lipid binding regulation of cell shape cytoplasmic side of plasma membrane membrane kinase activity phosphorylation transferase activity peptidyl-tyrosine phosphorylation cell differentiation cytoplasmic vesicle regulation of actin cytoskeleton organization intracellular signal transduction cell projection negative regulation of apoptotic process intracellular membrane-bounded organelle innate immune response innate immune response protein autophosphorylation regulation of phagocytosis defense response to Gram-positive bacterium regulation of DNA-binding transcription factor activity localization anchoring junction regulation of podosome assembly	04062 04666
1454713_s_at	Hdc	histidine decarboxylase	2	-126593659	BG072171	15186	219	histamine metabolic process histamine biosynthetic process histamine biosynthetic process histamine biosynthetic process histidine decarboxylase activity histidine decarboxylase activity histidine decarboxylase activity histidine decarboxylase activity cytoplasm amino acid metabolic process histidine metabolic process histidine catabolic process histidine catabolic process histidine catabolic process histidine catabolic process amino acid binding lyase activity carbon-carbon lyase activity carboxy-lyase activity carboxylic acid metabolic process pyridoxal phosphate binding dendrite catecholamine biosynthetic process identical protein binding neuronal cell body	00340 01100
1422018_at	Hivep2	human immunodeficiency virus type I enhancer binding protein 2	10	13966378, 13966074	NM_010437	15273	45	RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm transcription regulator complex DNA-templated transcription regulation of transcription by RNA polymerase II signal transduction positive regulation of transcription by RNA polymerase II metal ion binding
1455897_x_at	Hmgn1	high mobility group nucleosomal binding domain 1	16	-96121587	BF464696	15312	79	pyrimidine dimer repair by nucleotide-excision repair chromatin female germ cell nucleus DNA binding chromatin binding chromatin binding protein binding nucleus nucleus nucleoplasm cytoplasm transcription-coupled nucleotide-excision repair chromatin organization chromatin organization regulation of transcription by RNA polymerase II response to UV-B response to UV-C nucleosomal DNA binding regulation of development, heterochronic post-embryonic camera-type eye morphogenesis regulation of epithelial cell proliferation positive regulation of NAD+ ADP-ribosyltransferase activity
1436549_a_at	Hnrnpa1	heterogeneous nuclear ribonucleoprotein A1	15	103240396, 103240396	BE685966	15382	103	alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding DNA binding single-stranded DNA binding RNA binding single-stranded RNA binding mRNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding nucleus nucleus nucleoplasm spliceosomal complex cytoplasm mRNA processing RNA splicing positive regulation of gene expression protein domain specific binding RNA strand annealing activity miRNA binding cellular response to potassium ion pre-mRNA binding identical protein binding intracellular non-membrane-bounded organelle synapse synapse positive regulation of action potential mRNA transport telomeric repeat-containing RNA binding catalytic step 2 spliceosome catalytic step 2 spliceosome cellular response to organic substance G-rich strand telomeric DNA binding molecular condensate scaffold activity DNA/DNA annealing activity sequence-specific mRNA binding nucleoplasmic periphery of the nuclear pore complex ribonucleoprotein complex	03040
1448881_at	Hp	haptoglobin	8	-109575127	NM_017370	15439	97	liver development immune system process serine-type endopeptidase activity serine-type endopeptidase activity extracellular region extracellular space extracellular space extracellular space proteolysis acute-phase response Notch signaling pathway response to bacterium antioxidant activity hemoglobin binding haptoglobin-hemoglobin complex spherical high-density lipoprotein particle defense response to bacterium identical protein binding blood microparticle
1423944_at	Hpx	hemopexin	7	-105591610	BC011246	15458	45	positive regulation of immunoglobulin production positive regulation of humoral immune response mediated by circulating immunoglobulin extracellular region extracellular space extracellular space intracellular iron ion homeostasis tyrosine phosphorylation of STAT protein heme transmembrane transporter activity heme transport hemoglobin metabolic process heme binding heme metabolic process heme metabolic process positive regulation of tyrosine phosphorylation of STAT protein metal ion binding regulation of protein metabolic process positive regulation of response to type II interferon type II interferon-mediated signaling pathway positive regulation of type II interferon-mediated signaling pathway
1427127_x_at	Hspa1b	heat shock protein 1B	17	-34956428	M12573	15511	338	G protein-coupled receptor binding protease binding zona pellucida receptor complex signaling receptor binding protein binding ATP binding intracellular anatomical structure nucleus nucleus cytoplasm cytoplasm mitochondrion mitochondrion mitochondrial matrix centrosome centriole cytosol protein folding binding of sperm to zona pellucida response to heat inclusion body aggresome basolateral plasma membrane apical plasma membrane nuclear speck ATP hydrolysis activity ATP hydrolysis activity enzyme binding heat shock protein binding heat shock protein binding ubiquitin protein ligase binding positive regulation of proteasomal ubiquitin-dependent protein catabolic process protein-containing complex protein refolding histone deacetylase binding negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process protein folding chaperone protein folding chaperone protein folding chaperone cell body membrane raft perinuclear region of cytoplasm NF-kappaB binding unfolded protein binding chaperone cofactor-dependent protein refolding C3HC4-type RING finger domain binding ATP-dependent protein disaggregase activity regulation of mitotic spindle assembly ribonucleoprotein complex	03040 04010 04141 04144 04612 05145
1424067_at	Icam1	intercellular adhesion molecule 1	9	21015939	BC008626	15894	604	immunological synapse T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell acute inflammatory response to antigenic stimulus T cell antigen processing and presentation positive regulation of cellular extravasation integrin binding integrin binding extracellular space cell adhesion cell adhesion cell adhesion leukocyte cell-cell adhesion leukocyte cell-cell adhesion regulation of cell shape external side of plasma membrane cell surface membrane positive regulation of actin filament polymerization cell adhesion mediated by integrin adhesion of symbiont to host protein-containing complex binding membrane raft positive regulation of nitric oxide biosynthetic process positive regulation of vasoconstriction receptor-mediated virion attachment to host cell positive regulation of peptidyl-tyrosine phosphorylation negative regulation of calcium ion transport establishment of endothelial barrier extracellular exosome positive regulation of ERK1 and ERK2 cascade cellular response to glucose stimulus T cell extravasation establishment of endothelial intestinal barrier establishment of Sertoli cell barrier cell-cell adhesion regulation of ruffle assembly negative regulation of extrinsic apoptotic signaling pathway via death domain receptors cellular response to amyloid-beta positive regulation of leukocyte adhesion to vascular endothelial cell cellular response to leukemia inhibitory factor negative regulation of endothelial cell apoptotic process	04514 04650 04670 05143 05144 05150 05323 05416
1448862_at	Icam2	intercellular adhesion molecule 2	11	-106377655	NM_010494	15896	78	uropod integrin binding integrin binding protein binding plasma membrane microvillus cell adhesion cell adhesion membrane cleavage furrow cell projection cell periphery cell-cell adhesion	04514 04650
1425895_a_at	Id1	inhibitor of DNA binding 1, HLH protein	2	152736250	U43884	15901	323	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II endothelial cell morphogenesis protein binding nucleus nucleus nucleoplasm cytoplasm centrosome apoptotic process multicellular organism development heart development circadian rhythm positive regulation of gene expression positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression cell differentiation BMP signaling pathway protein destabilization protein destabilization positive regulation of actin filament bundle assembly circadian regulation of gene expression collagen metabolic process identical protein binding negative regulation of apoptotic process negative regulation of DNA binding regulation of MAPK cascade negative regulation of DNA-binding transcription factor activity protein self-association negative regulation of endothelial cell differentiation negative regulation of osteoblast differentiation regulation of angiogenesis negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription response to antibiotic protein dimerization activity rhythmic process positive regulation of epithelial cell proliferation negative regulation of dendrite morphogenesis lung morphogenesis lung vasculature development proteasome binding endothelial cell apoptotic process negative regulation of cold-induced thermogenesis transcription regulator activity transcription regulator inhibitor activity transcription regulator inhibitor activity regulation of vasculature development negative regulation of endothelial cell apoptotic process	04350
1435176_a_at	Id2	inhibitor of DNA binding 2	12	-25093798	BF019883	15902	477	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin euchromatin metanephros development natural killer cell differentiation natural killer cell differentiation thigmotaxis leukocyte differentiation membranous septum morphogenesis bundle of His development protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytosol regulation of transcription by RNA polymerase II multicellular organism development heart development circadian rhythm positive regulation of cell population proliferation adult locomotory behavior entrainment of circadian clock regulation of gene expression positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression negative regulation of gene expression oligodendrocyte development regulation of lipid metabolic process olfactory bulb development cell differentiation B cell differentiation erythrocyte differentiation circadian regulation of gene expression circadian regulation of gene expression protein-containing complex mammary gland epithelial cell proliferation regulation of circadian rhythm entrainment of circadian clock by photoperiod enucleate erythrocyte differentiation negative regulation of DNA binding negative regulation of DNA-binding transcription factor activity transmembrane transporter binding locomotor rhythm negative regulation of B cell differentiation positive regulation of fat cell differentiation positive regulation of erythrocyte differentiation positive regulation of macrophage differentiation regulation of neuron differentiation negative regulation of osteoblast differentiation positive regulation of blood pressure positive regulation of cell cycle negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription protein dimerization activity cell development cell maturation rhythmic process lymph node development Peyer's patch development embryonic digestive tract morphogenesis positive regulation of smooth muscle cell proliferation neuron fate commitment cell morphogenesis involved in neuron differentiation astrocyte differentiation oligodendrocyte differentiation positive regulation of astrocyte differentiation negative regulation of oligodendrocyte differentiation white fat cell differentiation negative regulation of muscle cell differentiation adipose tissue development mammary gland alveolus development epithelial cell differentiation involved in mammary gland alveolus development endodermal digestive tract morphogenesis RNA polymerase II-specific DNA-binding transcription factor binding cellular response to lithium ion dopaminergic neuron differentiation cellular senescence transcription regulator activity transcription regulator inhibitor activity negative regulation of dopaminergic neuron differentiation negative regulation of core promoter binding regulation of G1/S transition of mitotic cell cycle regulation of neural precursor cell proliferation	04350
1416630_at	Id3	inhibitor of DNA binding 3	4	136143821	NM_008321	15903	288	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II metanephros development protein binding nucleus nucleus cytoplasm regulation of DNA replication multicellular organism development central nervous system development heart development muscle organ development circadian rhythm positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression protein domain specific binding cell differentiation epithelial cell differentiation notochord development circadian regulation of gene expression odontogenesis positive regulation of apoptotic process bHLH transcription factor binding negative regulation of DNA-binding transcription factor activity negative regulation of myoblast differentiation negative regulation of osteoblast differentiation negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription protein dimerization activity rhythmic process cellular response to leptomycin B transcription regulator activity transcription regulator inhibitor activity leptomycin B binding	04350
1419647_a_at	Ier3	immediate early response 3	17	35821712	NM_133662	15937	44	response to protozoan negative regulation of systemic arterial blood pressure protein binding nucleus nucleus nucleus glycolytic process regulation of DNA repair DNA damage response DNA damage response mitotic G2 DNA damage checkpoint signaling intrinsic apoptotic signaling pathway in response to DNA damage membrane negative regulation of apoptotic process positive regulation of protein catabolic process negative regulation of glycolytic process regulation of nucleocytoplasmic transport negative regulation of inflammatory response negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway regulation of reactive oxygen species metabolic process
1418825_at	Irgm1	immunity-related GTPase family M member 1	11	-48865244	NM_008326	15944	95	autophagosome assembly autophagosome assembly Golgi membrane Golgi membrane nucleotide binding autophagosome membrane positive regulation of protein phosphorylation immune system process GTPase activity GTPase activity GTPase activity G protein activity GTP binding phosphatidylinositol-3,4,5-trisphosphate binding mitochondrion lysosome lysosomal membrane endosome late endosome autophagosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus lipid droplet cytosol plasma membrane autophagy defense response defense response lipid binding response to bacterium positive regulation of autophagy positive regulation of autophagy positive regulation of autophagy positive regulation of peptidyl-threonine phosphorylation membrane hydrolase activity protein kinase binding protein-macromolecule adaptor activity cytoplasmic vesicle protein destabilization mitochondrial membrane negative regulation of type I interferon production negative regulation of type I interferon production negative regulation of type II interferon production positive regulation of peptidyl-serine phosphorylation cellular response to interferon-beta defense response to bacterium defense response to bacterium defense response to bacterium cell projection positive regulation of macrophage activation negative regulation of canonical NF-kappaB signal transduction regulation of protein-containing complex assembly phosphatidylinositol-3,4-bisphosphate binding protein serine/threonine kinase activator activity autolysosome innate immune response innate immune response phagocytic vesicle negative regulation of defense response to virus negative regulation of defense response to virus CARD domain binding negative regulation of inflammatory response negative regulation of inflammatory response protein stabilization defense response to Gram-negative bacterium BH3 domain binding positive regulation of type II interferon-mediated signaling pathway positive regulation of type II interferon-mediated signaling pathway regulation of protein complex stability protein lipidation involved in autophagosome assembly CAMKK-AMPK signaling cascade protein-containing complex assembly nucleotide-binding oligomerization domain containing 2 signaling pathway protein targeting to vacuole involved in autophagy cellular response to lipopolysaccharide cellular response to type II interferon positive regulation of protein serine/threonine kinase activity regulation of mitochondrial fission positive regulation of mitochondrial fission autophagosome maturation cellular response to virus negative regulation of cGAS/STING signaling pathway negative regulation of NLRP3 inflammasome complex assembly negative regulation of NLRP3 inflammasome complex assembly positive regulation of autophagosome maturation positive regulation of autophagosome maturation positive regulation of mitophagy positive regulation of mitophagy cardiolipin binding cardiolipin binding negative regulation of hematopoietic stem cell proliferation positive regulation of xenophagy positive regulation of lysosome organization positive regulation of CD4-positive, alpha-beta T cell proliferation
1418930_at	Cxcl10	C-X-C motif chemokine ligand 10	5	-92346638	NM_021274	15945	338	positive regulation of leukocyte chemotaxis cytokine activity extracellular region extracellular space extracellular space extracellular space chemotaxis defense response inflammatory response inflammatory response immune response G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway chemokine activity chemokine activity heparin binding positive regulation of cell population proliferation response to bacterium external side of plasma membrane T cell chemotaxis regulation of T cell chemotaxis negative regulation of angiogenesis positive regulation of cell migration neutrophil chemotaxis killing of cells of another organism chemoattractant activity endothelial cell activation regulation of cell population proliferation regulation of apoptotic process CXCR chemokine receptor binding negative regulation of myoblast differentiation CXCR3 chemokine receptor binding positive regulation of release of sequestered calcium ion into cytosol defense response to virus antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide chemokine-mediated signaling pathway chemokine-mediated signaling pathway cellular response to lipopolysaccharide cellular response to lipopolysaccharide positive regulation of monocyte chemotaxis cellular response to interleukin-17 regulation of endothelial tube morphogenesis negative regulation of myoblast fusion positive regulation of T cell migration	04060 04062 04620 04622 04623
1419603_at	Ifi204	interferon activated gene 204	1	-173747293	NM_008329	15951	65	negative regulation of transcription by RNA polymerase II activation of innate immune response activation of innate immune response immune system process DNA binding double-stranded DNA binding double-stranded DNA binding double-stranded DNA binding transcription coregulator activity protein binding nucleus nucleoplasm nucleoplasm nucleolus nucleolus nucleolus cytoplasm cytosol cytosol regulation of transcription by RNA polymerase II multicellular organism development transcription factor binding response to bacterium nuclear speck monocyte differentiation ubiquitin protein ligase binding positive regulation of interleukin-1 beta production protein-containing complex cellular response to interferon-alpha cellular response to interferon-beta cellular response to interferon-beta cellular response to glucose starvation nuclear inclusion body intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator identical protein binding intracellular membrane-bounded organelle negative regulation of DNA binding negative regulation of viral genome replication innate immune response positive regulation of osteoblast differentiation negative regulation of gene expression, epigenetic negative regulation of innate immune response negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II inner ear development defense response to virus cellular response to ionizing radiation intrinsic apoptotic signaling pathway by p53 class mediator activation of cysteine-type endopeptidase activity negative regulation of AIM2 inflammasome complex assembly negative regulation of cysteine-type endopeptidase activity
1417292_at	Ifi47	interferon gamma inducible protein 47	11	49087016, 49076586	NM_008330	15953	20	GTPase activity endoplasmic reticulum endoplasmic reticulum membrane defense response defense response cellular response to interferon-beta
1450783_at	Ifit1	interferon-induced protein with tetratricopeptide repeats 1	19	34640888	NM_008331	15957	70	immune system process RNA binding RNA binding protein binding cytoplasm cytoplasm cytosol cytosol response to virus response to bacterium cellular response to interferon-alpha cellular response to interferon-beta innate immune response defense response to virus defense response to virus	05160
1418293_at	Ifit2	interferon-induced protein with tetratricopeptide repeats 2	19	34551087, 34550693	NM_008332	15958	45	immune system process RNA binding cytoplasm endoplasmic reticulum cytosol apoptotic process response to virus response to virus negative regulation of protein binding cellular response to interferon-alpha positive regulation of apoptotic process innate immune response defense response to virus defense response to virus antiviral innate immune response antiviral innate immune response
1449025_at	Ifit3	interferon-induced protein with tetratricopeptide repeats 3	19	34583528	NM_010501	15959	38	immune system process protein binding cytoplasm mitochondrion cytosol cytosol negative regulation of cell population proliferation response to virus response to bacterium cellular response to interferon-beta response to stilbenoid identical protein binding negative regulation of apoptotic process innate immune response defense response to virus defense response to virus antiviral innate immune response
1451462_a_at	Ifnar2	interferon (alpha and beta) receptor 2	16	91372782, 91372782, 91372782	AF013486	15976	96	type I interferon receptor activity type I interferon receptor activity type I interferon receptor activity extracellular region extracellular space extracellular space extracellular space plasma membrane regulation of transcription by RNA polymerase II receptor signaling pathway via JAK-STAT membrane protein kinase binding cytokine binding type I interferon binding immature T cell proliferation in thymus response to interferon-alpha response to interferon-beta cellular response to interferon-beta interleukin-22 receptor activity defense response to virus type I interferon-mediated signaling pathway type I interferon-mediated signaling pathway	04060 04380 04620 04630 04650 05160
1417640_at	Cd79b	CD79B antigen	11	-106311340	NM_008339	15985	66	adaptive immune response immune system process transmembrane signaling receptor activity protein binding plasma membrane plasma membrane cell surface receptor signaling pathway response to bacterium external side of plasma membrane external side of plasma membrane membrane B cell receptor complex B cell receptor complex B cell differentiation identical protein binding identical protein binding B cell receptor signaling pathway B cell receptor signaling pathway IgM B cell receptor complex	04662
1423756_s_at	Igfbp4	insulin-like growth factor binding protein 4	11	99041243	BC019836	16010	107	MAPK cascade regulation of cell growth protein binding insulin-like growth factor binding extracellular region extracellular space extracellular space extracellular space regulation of glucose metabolic process growth factor binding insulin-like growth factor I binding insulin-like growth factor II binding regulation of growth positive regulation of MAPK cascade regulation of insulin-like growth factor receptor signaling pathway positive regulation of insulin-like growth factor receptor signaling pathway type B pancreatic cell proliferation
1417933_at	Igfbp6	insulin-like growth factor binding protein 6	15	102144185	NM_008344	16012	47	fibronectin binding extracellular matrix structural constituent insulin-like growth factor binding extracellular region extracellular space extracellular space extracellular space cell migration growth factor binding insulin-like growth factor I binding insulin-like growth factor I binding insulin-like growth factor II binding insulin-like growth factor II binding positive regulation of stress-activated MAPK cascade insulin-like growth factor binary complex identical protein binding positive regulation of MAPK cascade regulation of insulin-like growth factor receptor signaling pathway collagen-containing extracellular matrix
1427329_a_at	Ighm	immunoglobulin heavy constant mu	12		AI326478	16019	911	MAPK cascade adaptive immune response pre-B cell allelic exclusion B cell affinity maturation humoral immune response mediated by circulating immunoglobulin regulation of immunoglobulin production single-stranded DNA binding antigen binding antigen binding transmembrane signaling receptor activity protein binding extracellular region extracellular space extracellular space cytoplasm plasma membrane plasma membrane complement activation, classical pathway external side of plasma membrane cell surface cell surface membrane immunoglobulin mediated immune response peptidyl-tyrosine phosphorylation antibacterial humoral response antibacterial humoral response B cell receptor complex antigen processing and presentation regulation of cell morphogenesis positive regulation of B cell proliferation phosphatidylcholine binding immunoglobulin receptor binding immunoglobulin receptor binding immunoglobulin receptor binding B cell proliferation B cell activation immunoglobulin complex, circulating immunoglobulin complex, circulating identical protein binding peptidoglycan binding positive regulation of MAPK cascade early endosome to late endosome transport innate immune response positive regulation of endocytosis perinuclear region of cytoplasm positive regulation of peptidyl-tyrosine phosphorylation positive regulation of immune response defense response to Gram-negative bacterium defense response to Gram-negative bacterium B cell receptor signaling pathway positive regulation of B cell activation IgM B cell receptor complex pentameric IgM immunoglobulin complex hexameric IgM immunoglobulin complex
1450424_a_at	Il18bp	interleukin 18 binding protein	7	-102015073	AF110803	16068	33	extracellular region extracellular space extracellular space interleukin-18 binding interleukin-18 binding T-helper 1 type immune response T-helper 1 type immune response
1430523_s_at	Iglv1	immunoglobulin lambda variable 1	16		AK008145	16142	57	immunoglobulin production extracellular space immune response
1425519_a_at	Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	18	60803848	BC003476	16149	242	prostaglandin biosynthetic process amyloid-beta binding positive regulation of protein phosphorylation positive regulation of cytokine-mediated signaling pathway positive regulation of cytokine-mediated signaling pathway positive regulation of cytokine-mediated signaling pathway adaptive immune response T cell activation involved in immune response immune system process positive regulation of dendritic cell antigen processing and presentation negative regulation of peptide secretion positive regulation of adaptive immune response positive regulation of type 2 immune response positive regulation of type 2 immune response negative regulation of mature B cell apoptotic process cytokine receptor activity cytokine receptor activity cytokine receptor activity protein binding extracellular region extracellular space nucleus cytoplasm cytoplasm lysosome endosome late endosome multivesicular body vacuole endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane plasma membrane plasma membrane intracellular protein transport intracellular protein transport defense response immune response external side of plasma membrane cell surface cell surface positive regulation of gene expression membrane immunoglobulin mediated immune response antigen processing and presentation antigen processing and presentation antigen processing and presentation antigen processing and presentation of exogenous peptide antigen via MHC class II cytokine binding cytokine binding MHC class II protein complex binding negative regulation of cell migration positive regulation of B cell proliferation positive regulation of prostaglandin biosynthetic process positive regulation of chemokine production positive regulation of interleukin-6 production positive regulation of interleukin-8 production protein-containing complex positive regulation of kinase activity positive regulation of kinase activity response to type II interferon response to type II interferon macrophage migration inhibitory factor signaling pathway macrophage migration inhibitory factor receptor complex macrophage migration inhibitory factor receptor complex NOS2-CD74 complex macrophage migration inhibitory factor binding macrophage migration inhibitory factor binding MHC class II protein binding MHC class II protein binding CD4 receptor binding MHC class II protein complex MHC class II protein binding, via antigen binding groove negative regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction positive regulation of MAPK cascade negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of DNA damage response, signal transduction by p53 class mediator protein folding chaperone positive thymic T cell selection negative thymic T cell selection positive regulation of innate immune response negative regulation of T cell differentiation positive regulation of T cell differentiation positive regulation of monocyte differentiation positive regulation of DNA-templated transcription negative regulation of viral entry into host cell positive regulation of viral entry into host cell positive regulation of fibroblast proliferation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation positive regulation of peptidyl-tyrosine phosphorylation protein stabilization nitric-oxide synthase binding chaperone cofactor-dependent protein refolding chaperone cofactor-dependent protein refolding positive regulation of macrophage cytokine production positive regulation of macrophage cytokine production protein-containing complex assembly protein trimerization positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade positive regulation of neutrophil chemotaxis negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator positive regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of macrophage migration inhibitory factor signaling pathway	04612
1426207_at	Ikbkb	inhibitor of kappaB kinase beta	8	-22659204	AF088910	16150	508	nucleotide binding B cell homeostasis protein kinase activity protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus cytoplasm cytoplasm cytoplasm cytosol protein phosphorylation canonical NF-kappaB signal transduction canonical NF-kappaB signal transduction I-kappaB phosphorylation positive regulation of cell population proliferation IkappaB kinase activity IkappaB kinase activity IkappaB kinase activity IkappaB kinase complex IkappaB kinase complex IkappaB kinase complex cytoplasmic side of plasma membrane positive regulation of sodium ion transport positive regulation of neuron projection development membrane kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation peptidyl-serine phosphorylation protein kinase binding protein phosphatase binding cortical actin cytoskeleton organization neuron projection development tumor necrosis factor-mediated signaling pathway tumor necrosis factor-mediated signaling pathway tumor necrosis factor-mediated signaling pathway tumor necrosis factor-mediated signaling pathway negative regulation of myosin-light-chain-phosphatase activity CD40 receptor complex regulation of phosphorylation identical protein binding protein homodimerization activity positive regulation of canonical NF-kappaB signal transduction protein-containing complex binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein heterodimerization activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity protein maturation response to cholecystokinin interleukin-1-mediated signaling pathway cellular response to tumor necrosis factor protein localization to plasma membrane scaffold protein binding regulation of establishment of endothelial barrier negative regulation of bicellular tight junction assembly transferrin receptor binding positive regulation of cation channel activity	04010 04062 04210 04380 04620 04621 04622 04623 04660 04662 04722 04910 04920 04930 05142 05145 05160 05200 05212 05215 05220 05221 05222
1425454_a_at	Il12a	interleukin 12a	3	68691423, 68690643	AF128210	16159	485	positive regulation of T cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target cytokine activity cytokine activity interleukin-12 receptor binding protein binding extracellular region extracellular region extracellular space extracellular space cytoplasm endoplasmic reticulum lumen Golgi lumen immune response growth factor activity cell population proliferation cell population proliferation cell surface response to UV-B cell migration endosome lumen response to lipopolysaccharide type II interferon production type II interferon production negative regulation of interleukin-17 production positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of natural killer cell activation positive regulation of mononuclear cell proliferation positive regulation of smooth muscle cell apoptotic process T-helper 1 cell activation interleukin-12-mediated signaling pathway T-helper 1 cell cytokine production T cell proliferation positive regulation of T cell proliferation interleukin-12 beta subunit binding interleukin-12 beta subunit binding positive regulation of tyrosine phosphorylation of STAT protein defense response to protozoan defense response to protozoan interleukin-12 complex interleukin-12 complex interleukin-12 complex interleukin-27 binding positive regulation of T cell differentiation positive regulation of cell adhesion positive regulation of natural killer cell mediated cytotoxicity protein heterodimerization activity negative regulation of smooth muscle cell proliferation positive regulation of lymphocyte proliferation negative regulation of protein secretion positive regulation of NK T cell activation cellular response to lipopolysaccharide extrinsic apoptotic signaling pathway cellular response to virus negative regulation of vascular endothelial growth factor signaling pathway negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis positive regulation of dendritic cell chemotaxis	04060 04620 04622 04630 04940 05140 05142 05143 05144 05145 05146 05330
1427164_at	Il13ra1	interleukin 13 receptor, alpha 1	X	36112107	BB730912	16164	69	cytokine receptor activity cytokine receptor activity positive regulation of cell population proliferation external side of plasma membrane membrane interleukin-13 receptor activity cytokine-mediated signaling pathway cytokine binding receptor complex	04060 04630
1448681_at	Il15ra	interleukin 15 receptor, alpha chain	2	11705711, 11705292	NM_133836	16169	160	natural killer cell differentiation extracellular region nucleus plasma membrane receptor signaling pathway via JAK-STAT cell surface negative regulation of neuron projection development membrane protein kinase binding cytoplasmic vesicle positive regulation of natural killer cell differentiation interleukin-15-mediated signaling pathway interleukin-15-mediated signaling pathway interleukin-15 receptor activity interleukin-15 receptor activity positive regulation of phagocytosis	04060 04630 04672
1417391_a_at	Il16	interleukin 16	7	-83642818, -83642818, -83642818	BC026894	16170	47	cytokine activity cytokine activity protein binding extracellular region extracellular space intracellular anatomical structure nucleus cytoplasm cytosol plasma membrane focal adhesion chemotaxis signal transduction positive regulation of gene expression nuclear speck cytokine-mediated signaling pathway leukocyte chemotaxis leukocyte chemotaxis positive regulation of chemokine production positive regulation of interleukin-1 alpha production positive regulation of interleukin-12 production positive regulation of interleukin-6 production CD4 receptor binding CD4 receptor binding positive regulation of inflammatory response induction of positive chemotaxis induction of positive chemotaxis regulation of calcium ion transport collagen-containing extracellular matrix Flemming body positive regulation of neutrophil activation
1417932_at	Il18	interleukin 18	9	50554699	NM_008360	16173	644	angiogenesis angiogenesis response to hypoxia cytokine activity cytokine activity cytokine activity extracellular region extracellular space extracellular space cytoplasm inflammatory response immune response cell population proliferation cell population proliferation extrinsic apoptotic signaling pathway via death domain receptors positive regulation of gene expression positive regulation of macrophage derived foam cell differentiation positive regulation of smooth muscle cell migration apical plasma membrane natural killer cell activation regulation of cell adhesion regulation of cell adhesion sleep sleep type II interferon production interleukin-6 production positive regulation of chemokine production positive regulation of granulocyte macrophage colony-stimulating factor production positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of interleukin-13 production positive regulation of interleukin-17 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of natural killer cell proliferation positive regulation of superoxide anion generation positive regulation of collagen biosynthetic process negative regulation of neutrophil apoptotic process interleukin-18-mediated signaling pathway interleukin-18-mediated signaling pathway T-helper 1 cell cytokine production T-helper 1 cell cytokine production T-helper 1 type immune response T-helper 1 type immune response positive regulation of activated T cell proliferation positive regulation of activated T cell proliferation neutrophil activation natural killer cell mediated cytotoxicity positive regulation of tyrosine phosphorylation of STAT protein cholesterol homeostasis positive regulation of apoptotic process positive regulation of vascular permeability positive regulation of neuron apoptotic process interleukin-18 receptor binding positive regulation of T-helper 2 cell differentiation negative regulation of myoblast differentiation positive regulation of transcription by RNA polymerase II receptor ligand activity positive regulation of smooth muscle cell proliferation positive regulation of inflammatory response negative regulation of peptidyl-tyrosine phosphorylation defense response to Gram-positive bacterium detection of mechanical stimulus involved in sensory perception of pain positive regulation of NF-kappaB transcription factor activity positive regulation of NK T cell proliferation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction establishment of skin barrier triglyceride homeostasis cellular response to peptide hormone stimulus positive regulation of cold-induced thermogenesis positive regulation of non-canonical NF-kappaB signal transduction positive regulation of male germ cell proliferation positive regulation of hepatocyte proliferation positive regulation of blood vessel remodeling positive regulation of T-helper 1 cell cytokine production	04060 04621 04623 05143 05144 05323
1421291_at	Il18rap	interleukin 18 receptor accessory protein	1	40515361	NM_010553	16174	17	interleukin-1 receptor activity plasma membrane inflammatory response signal transduction cell population proliferation coreceptor activity membrane hydrolase activity type II interferon production interleukin-6 production interleukin-18-mediated signaling pathway interleukin-18-mediated signaling pathway interleukin-18-mediated signaling pathway T-helper 1 cell cytokine production interleukin-18 receptor activity interleukin-18 receptor activity neutrophil activation interleukin-18 receptor complex positive regulation of natural killer cell mediated cytotoxicity NADP+ nucleosidase activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity NAD+ nucleotidase, cyclic ADP-ribose generating cellular response to interleukin-18	04060
1419532_at	Il1r2	interleukin 1 receptor, type II	1	40084713, 40086092	NM_010555	16178	56	interleukin-1 receptor activity interleukin-1 receptor activity interleukin-1, type II, blocking receptor activity extracellular region cytoplasm plasma membrane negative regulation of protein processing membrane protein processing interleukin-1 binding interleukin-1 binding negative regulation of interleukin-1 alpha production negative regulation of cytokine production involved in inflammatory response negative regulation of interleukin-1-mediated signaling pathway	04010 04060 04640 05146
1421844_at	Il1rap	interleukin 1 receptor accessory protein	16	26581704, 26581704, 26581704, 26581704	BE285634	16180	54	interleukin-33 receptor activity immune system process interleukin-1 receptor activity interleukin-1 receptor activity interleukin-1 receptor binding interleukin-1 receptor binding protein binding extracellular region plasma membrane inflammatory response signal transduction coreceptor activity membrane hydrolase activity cytokine-mediated signaling pathway interleukin-2 production positive regulation of interleukin-13 production positive regulation of interleukin-4 production positive regulation of interleukin-5 production positive regulation of interleukin-6 production protein-containing complex interleukin-33-mediated signaling pathway interleukin-33-mediated signaling pathway innate immune response synapse synapse NADP+ nucleosidase activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of synapse assembly NAD+ nucleotidase, cyclic ADP-ribose generating interleukin-1-mediated signaling pathway glutamatergic synapse glutamatergic synapse regulation of postsynaptic density assembly regulation of postsynaptic density assembly trans-synaptic signaling by trans-synaptic complex trans-synaptic signaling by trans-synaptic complex synaptic membrane adhesion synaptic membrane adhesion regulation of presynapse assembly regulation of presynapse assembly	04060 04210
1451798_at	Il1rn	interleukin 1 receptor antagonist	2	24345370, 24345290, 24336859	M57525	16181	200	fever generation inflammatory response to antigenic stimulus cytokine activity interleukin-1 receptor binding interleukin-1, type I receptor binding interleukin-1, type II receptor binding interleukin-1 receptor antagonist activity interleukin-1 receptor antagonist activity extracellular region extracellular space extracellular space nucleoplasm cytoplasm centrosome cytosol lipid metabolic process acute-phase response inflammatory response immune response memory negative regulation of glutamate secretion insulin secretion negative regulation of cell migration vesicle negative regulation of heterotypic cell-cell adhesion negative regulation of apoptotic process interleukin-1 type I receptor antagonist activity interleukin-1 type II receptor antagonist activity negative regulation of membrane potential response to glucocorticoid negative regulation of interleukin-1-mediated signaling pathway negative regulation of interleukin-1-mediated signaling pathway
1416295_a_at	Il2rg	interleukin 2 receptor, gamma chain	X	-101264384	L20048	16186	822	mature B cell differentiation CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation cytokine receptor activity cytokine receptor activity nucleoplasm endoplasmic reticulum plasma membrane plasma membrane external side of plasma membrane external side of plasma membrane cell surface gene expression regulation of gene expression positive regulation of gene expression coreceptor activity membrane cytokine-mediated signaling pathway cytokine binding interleukin-2 binding lymphocyte differentiation B cell differentiation positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation T cell differentiation in thymus positive regulation of T cell differentiation in thymus interleukin-15-mediated signaling pathway interleukin-2-mediated signaling pathway interleukin-9-mediated signaling pathway interleukin-15 receptor activity receptor complex positive regulation of B cell differentiation positive regulation of phagocytosis	04060 04144 04630 05340
1452843_at	Il6st	interleukin 6 signal transducer	13	112464069	AK017211	16195	319	cytokine receptor activity cytokine receptor activity ciliary neurotrophic factor receptor activity interleukin-6 receptor activity interleukin-6 receptor activity interleukin-11 receptor activity leukemia inhibitory factor receptor activity oncostatin-M receptor activity ciliary neurotrophic factor receptor binding interleukin-6 receptor binding protein binding extracellular space plasma membrane interleukin-6 receptor complex oncostatin-M receptor complex glycogen metabolic process triglyceride mobilization signal transduction positive regulation of cell population proliferation positive regulation of cell population proliferation regulation of Notch signaling pathway external side of plasma membrane external side of plasma membrane positive regulation of smooth muscle cell migration coreceptor activity membrane cytokine-mediated signaling pathway cytokine-mediated signaling pathway cytokine-mediated signaling pathway growth factor binding cytokine binding interleukin-11 binding interleukin-6 binding interleukin-6 binding protein tyrosine kinase activator activity dendrite neuronal cell body membrane response to cytokine interleukin-11-mediated signaling pathway oncostatin-M-mediated signaling pathway positive regulation of T cell proliferation positive regulation of tyrosine phosphorylation of STAT protein identical protein binding neuronal cell body receptor complex negative regulation of neuron apoptotic process cell body membrane raft positive regulation of osteoblast differentiation positive regulation of Notch signaling pathway positive regulation of Notch signaling pathway positive regulation of astrocyte differentiation leukemia inhibitory factor signaling pathway negative regulation of cytosolic calcium ion concentration intestinal epithelial cell development intestinal epithelial cell development interleukin-6-mediated signaling pathway interleukin-6-mediated signaling pathway negative regulation of interleukin-6-mediated signaling pathway interleukin-27-mediated signaling pathway ciliary neurotrophic factor receptor complex ciliary neurotrophic factor-mediated signaling pathway scaffold protein binding	04060 04630
1448575_at	Il7r	interleukin 7 receptor	15	-9506158	AI573431	16197	391	cell morphogenesis B cell homeostasis T cell mediated cytotoxicity negative regulation of T cell mediated cytotoxicity immunoglobulin production cytokine receptor activity cytokine receptor activity nucleoplasm cytosol plasma membrane plasma membrane positive regulation of cell population proliferation regulation of cell size regulation of cell size external side of plasma membrane external side of plasma membrane gene expression positive regulation of gene expression membrane cytokine-mediated signaling pathway hemopoiesis T cell differentiation T cell differentiation T cell differentiation in thymus positive regulation of T cell differentiation in thymus B cell proliferation B cell proliferation T cell homeostasis positive regulation of receptor signaling pathway via JAK-STAT lymph node development defense response to Gram-positive bacterium negative regulation of T cell apoptotic process positive regulation of receptor signaling pathway via STAT	04060 04630 04640 05340
1460669_at	Ilf3	interleukin enhancer binding factor 3	9	21367870, 21368531, 21367870	NM_010561	16201	75	virus receptor activity DNA binding DNA binding RNA binding double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding nucleus nucleus nucleoplasm nucleolus cytoplasm cytoplasm mitochondrion protein phosphorylation protein phosphorylation protein methylation negative regulation of translation enzyme binding mRNA 3'-UTR AU-rich region binding negative regulation of viral genome replication negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription defense response to virus ribonucleoprotein complex
1449988_at	Gimap1	GTPase, IMAP family member 1	6	48739046	NM_008376	16205	23	nucleotide binding GTP binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum Golgi apparatus membrane B cell differentiation CD4-positive, alpha-beta T cell differentiation CD8-positive, alpha-beta T cell differentiation
1460432_a_at	Eif3e	eukaryotic translation initiation factor 3, subunit E	15	-43250039	AK002576	16341	49	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay translation initiation factor activity translation initiation factor activity nucleus nucleus cytoplasm cytosol eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex eukaryotic translation initiation factor 3 complex translation translational initiation translational initiation translational initiation intracellular calcium ion homeostasis postsynaptic density postsynaptic density PML body transmembrane transporter binding positive regulation of translation positive regulation of intracellular protein transport positive regulation of mRNA binding	03013 05160
1448436_a_at	Irf1	interferon regulatory factor 1	11	53770013, 53770013, 53770472	NM_008390	16362	333	chromatin transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific immune system process immune system process regulation of adaptive immune response DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleus cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II apoptotic process canonical NF-kappaB signal transduction regulation of gene expression positive regulation of type I interferon production positive regulation of interferon-beta production positive regulation of interleukin-12 production positive regulation of interleukin-12 production positive regulation of natural killer cell differentiation regulation of MyD88-dependent toll-like receptor signaling pathway toll-like receptor 3 signaling pathway cellular response to interferon-beta negative regulation of tyrosine phosphorylation of STAT protein positive regulation of apoptotic process CD8-positive, alpha-beta T cell differentiation sequence-specific DNA binding sequence-specific DNA binding innate immune response regulation of innate immune response negative regulation of regulatory T cell differentiation positive regulation of T-helper 1 cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II defense response to virus defense response to virus regulation of cell cycle type II interferon-mediated signaling pathway response to growth hormone cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to peptide hormone stimulus regulation of CD8-positive, alpha-beta T cell proliferation	05160
1421173_at	Irf4	interferon regulatory factor 4	13	30749232	U34307	16364	301	nucleosome transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific immune system process DNA binding DNA-binding transcription factor activity transcription coactivator activity protein binding nucleus nucleus nucleoplasm cytosol chromatin remodeling regulation of DNA-templated transcription regulation of transcription by RNA polymerase II positive regulation of interleukin-10 production positive regulation of interleukin-13 production positive regulation of interleukin-2 production positive regulation of interleukin-4 production negative regulation of toll-like receptor signaling pathway defense response to protozoan myeloid dendritic cell differentiation positive regulation of DNA binding sequence-specific DNA binding positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II T-helper 17 cell lineage commitment positive regulation of cold-induced thermogenesis sequence-specific double-stranded DNA binding
1427381_at	Acod1	aconitate decarboxylase 1	14	103047011	L38281	16365	73	immune system process positive regulation of antimicrobial humoral response positive regulation of antimicrobial humoral response mitochondrion mitochondrion defense response defense response defense response inflammatory response embryo implantation response to bacterium lyase activity negative regulation of NF-kappaB transcription factor activity negative regulation of type I interferon production response to lipopolysaccharide negative regulation of toll-like receptor 2 signaling pathway negative regulation of toll-like receptor 4 signaling pathway cellular response to interferon-beta protein homodimerization activity protein homodimerization activity innate immune response negative regulation of innate immune response aconitate decarboxylase activity aconitate decarboxylase activity aconitate decarboxylase activity aconitate decarboxylase activity negative regulation of inflammatory response defense response to virus cellular response to molecule of bacterial origin cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to type II interferon cellular response to interleukin-1 cellular response to tumor necrosis factor cellular response to progesterone stimulus tolerance induction to lipopolysaccharide tolerance induction to lipopolysaccharide positive regulation of reactive oxygen species metabolic process
1422046_at	Itgam	integrin alpha M	7	128062639	NM_008401	16409	576	microglial cell activation neutrophil apoptotic process opsonin binding opsonin binding complement component C3b binding complement receptor mediated signaling pathway leukocyte migration involved in inflammatory response integrin binding protein binding extracellular space nucleus plasma membrane plasma membrane receptor-mediated endocytosis phagocytosis phagocytosis, engulfment cell adhesion cell adhesion leukocyte cell-cell adhesion cell-matrix adhesion integrin-mediated signaling pathway heparin binding integrin complex external side of plasma membrane external side of plasma membrane cell surface cell surface microglia development membrane neutrophil chemotaxis forebrain development heat shock protein binding positive regulation of superoxide anion generation positive regulation of superoxide anion generation positive regulation of superoxide anion generation cell adhesion mediated by integrin integrin alphaM-beta2 complex cargo receptor activity cargo receptor activity positive regulation of neutrophil degranulation heparan sulfate proteoglycan binding plasma membrane raft cellular extravasation negative regulation of dopamine metabolic process activated T cell proliferation positive regulation of mast cell differentiation leukocyte adhesion to vascular endothelial cell positive regulation of protein targeting to membrane amyloid-beta clearance amyloid-beta clearance cell-cell adhesion cell-cell adhesion complement-mediated synapse pruning vertebrate eye-specific patterning positive regulation of microglial cell mediated cytotoxicity positive regulation of prostaglandin-E synthase activity	04145 04514 04640 04670 04810 05140 05146 05150
1449829_at	Itgb2l	integrin beta 2-like	16	-96422297	NM_008405	16415	19	amyloid-beta binding leukocyte migration involved in inflammatory response integrin binding plasma membrane focal adhesion inflammatory response cell adhesion leukocyte cell-cell adhesion leukocyte cell-cell adhesion cell-matrix adhesion cell-matrix adhesion integrin-mediated signaling pathway integrin-mediated signaling pathway integrin complex cell surface cell surface membrane protein kinase binding protein kinase binding secretory granule ICAM-3 receptor activity neutrophil chemotaxis neutrophil chemotaxis heat shock protein binding positive regulation of superoxide anion generation cell adhesion mediated by integrin heterotypic cell-cell adhesion integrin alphaL-beta2 complex receptor clustering positive regulation of neutrophil degranulation endothelial cell migration plasma membrane raft protein-containing complex binding cellular extravasation positive regulation of nitric oxide biosynthetic process positive regulation of angiogenesis regulation of peptidyl-tyrosine phosphorylation cell adhesion molecule binding cell-cell adhesion neutrophil migration	04145 04514 04650 04670 04810 05140 05144 05146 05150 05323 05416
1431808_a_at	Itih4	inter alpha-trypsin inhibitor, heavy chain 4	14	30886475	AK004893	16427	30	serine-type endopeptidase inhibitor activity protein binding extracellular region extracellular space cytoplasm plasma membrane acute-phase response negative regulation of peptidase activity hyaluronan metabolic process peptidase inhibitor activity collagen-containing extracellular matrix
1417171_at	Itk	IL2 inducible T cell kinase	11	-46325147, -46344477	NM_010583	16428	153	nucleotide binding positive regulation of cytokine production NK T cell differentiation NK T cell differentiation NK T cell differentiation adaptive immune response adaptive immune response immune system process protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding nucleus cytoplasm cytosol cytosol plasma membrane cell-cell junction protein phosphorylation protein phosphorylation activation of phospholipase C activity kinase activity phosphorylation transferase activity type II interferon production type II interferon production interleukin-4 production interleukin-4 production intracellular signal transduction gamma-delta T cell activation metal ion binding T cell receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway	04062 04660 04670
1423608_at	Itm2a	integral membrane protein 2A	X	-107397194	BI966443	16431	31	amyloid-beta binding plasma cell differentiation immunoglobulin production Golgi apparatus plasma membrane membrane negative regulation of amyloid precursor protein biosynthetic process
1460203_at	Itpr1	inositol 1,4,5-trisphosphate receptor 1	6	108213095	NM_010585	16438	306	cell morphogenesis response to hypoxia response to hypoxia monoatomic ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium ion binding protein binding nuclear envelope nuclear envelope nuclear inner membrane nucleolus cytoplasm endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane plasma membrane calcineurin complex monoatomic ion transport calcium ion transport apoptotic process phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway post-embryonic development positive regulation of neuron projection development postsynaptic density calcium-release channel activity membrane sarcoplasmic reticulum sarcoplasmic reticulum sarcoplasmic reticulum calcium-mediated signaling calcium channel inhibitor activity protein phosphatase binding protein domain specific binding dendrite secretory granule membrane smooth endoplasmic reticulum membrane platelet dense granule membrane platelet dense tubular network cytoplasmic vesicle positive regulation of insulin secretion positive regulation of insulin secretion endoplasmic reticulum calcium ion homeostasis protein-containing complex protein-containing complex monoatomic ion transmembrane transport phosphatidylinositol binding phosphatidylinositol binding epithelial fluid transport identical protein binding neuronal cell body positive regulation of apoptotic process negative regulation of apoptotic process transmembrane transporter binding protein-containing complex binding synapse perinuclear region of cytoplasm negative regulation of calcium-mediated signaling voluntary musculoskeletal movement release of sequestered calcium ion into cytosol release of sequestered calcium ion into cytosol release of sequestered calcium ion into cytosol positive regulation of calcium ion transport transmembrane transport intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress calcium ion transmembrane transport inositol 1,4,5 trisphosphate binding inositol 1,4,5 trisphosphate binding cellular response to cAMP synaptic membrane liver regeneration Schaffer collateral - CA1 synapse Schaffer collateral - CA1 synapse Schaffer collateral - CA1 synapse inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels presynapse postsynapse GABA-ergic synapse ion channel modulating, G protein-coupled receptor signaling pathway ion channel modulating, G protein-coupled receptor signaling pathway regulation of postsynaptic cytosolic calcium ion concentration ligand-gated ion channel signaling pathway ligand-gated ion channel signaling pathway positive regulation of hepatocyte proliferation	04020 04070 04114 04270 04540 04720 04730 04912 04970 04971 04972 05010 05016
1417297_at	Itpr3	inositol 1,4,5-triphosphate receptor 3	17	27057303	NM_080553	16440	192	inositol hexakisphosphate binding monoatomic ion channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium channel activity calcium ion binding calcium ion binding protein binding nucleus nuclear envelope nuclear outer membrane nucleoplasm nucleolus cytoplasm endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane plasma membrane plasma membrane brush border monoatomic ion transport calcium ion transport G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration memory calcium-release channel activity membrane apical plasma membrane sarcoplasmic reticulum dendrite secretory granule membrane monoatomic ion transmembrane transport phosphatidylinositol binding phosphatidylinositol binding identical protein binding neuronal cell body receptor complex inositol 1,3,4,5 tetrakisphosphate binding protein-containing complex binding apical part of cell perinuclear region of cytoplasm sensory perception of bitter taste sensory perception of sweet taste sensory perception of umami taste release of sequestered calcium ion into cytosol response to calcium ion calcium ion homeostasis transmembrane transport long-term synaptic potentiation calcium ion transmembrane transport inositol 1,4,5 trisphosphate binding inositol 1,4,5 trisphosphate binding cellular response to cAMP cytoplasmic side of endoplasmic reticulum membrane presynapse	04020 04070 04114 04270 04540 04720 04730 04742 04912 04970 04971 04972 05010
1417409_at	Jun	jun proto-oncogene	4	-95049035	NM_010591	16476	764	negative regulation of transcription by RNA polymerase II chromatin euchromatin transcription cis-regulatory region binding transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific angiogenesis angiogenesis microglial cell activation release of cytochrome c from mitochondria liver development positive regulation of endothelial cell proliferation outflow tract morphogenesis DNA binding chromatin binding double-stranded DNA binding DNA-binding transcription factor activity GTPase activator activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex transcription regulator complex transcription regulator complex cytosol DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II apoptotic process transforming growth factor beta receptor signaling pathway learning transcription factor binding cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation response to xenobiotic stimulus positive regulation of epithelial cell migration transcription repressor complex release from viral latency enzyme binding monocyte differentiation axon regeneration ubiquitin protein ligase binding negative regulation of protein autophosphorylation protein-containing complex cellular response to reactive oxygen species response to endoplasmic reticulum stress leading edge cell differentiation cAMP response element binding transcription factor AP-1 complex transcription factor AP-1 complex response to muscle stretch regulation of cell population proliferation identical protein binding positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of DNA binding negative regulation of neuron apoptotic process positive regulation of neuron apoptotic process sequence-specific DNA binding negative regulation by host of viral transcription positive regulation by host of viral transcription ubiquitin-like protein ligase binding protein-containing complex binding positive regulation of monocyte differentiation positive regulation of DNA replication negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of fibroblast proliferation positive regulation of fibroblast proliferation positive regulation of smooth muscle cell proliferation cellular response to potassium ion starvation regulation of cell cycle regulation of cell cycle membrane depolarization SMAD protein signal transduction eyelid development in camera-type eye RNA polymerase II-specific DNA-binding transcription factor binding positive regulation of ERK1 and ERK2 cascade R-SMAD binding cellular response to cadmium ion cellular response to calcium ion HMG box domain binding cellular response to anisomycin RNA polymerase II transcription regulator complex general transcription initiation factor binding positive regulation of miRNA transcription positive regulation of vascular associated smooth muscle cell proliferation sequence-specific double-stranded DNA binding positive regulation of DNA-templated transcription initiation	04010 04012 04310 04380 04510 04620 04660 04662 04722 04912 05140 05142 05200 05210 05211 05323
1435772_at	Kif21b	kinesin family member 21B	1	136131389	AV122249	16565	37	nucleotide binding microtubule motor activity microtubule motor activity ATP binding cytoplasm cytoskeleton kinesin complex microtubule microtubule microtubule-based movement microtubule-based movement brain development microtubule binding microtubule binding ATP hydrolysis activity corpus callosum development cytoplasmic vesicle cell projection
1416021_a_at	Fabp5	fatty acid binding protein 5, epidermal	3	10012584	BC002008	16592	150	retinoic acid binding long-chain fatty acid transporter activity fatty acid binding fatty acid binding extracellular region extracellular space nucleus nucleus nucleus cytoplasm cytoplasm cytosol glucose metabolic process lipid metabolic process phosphatidylcholine biosynthetic process lipid transport lipid binding negative regulation of glucose transmembrane transport postsynaptic density fatty acid transport regulation of prostaglandin biosynthetic process positive regulation of peroxisome proliferator activated receptor signaling pathway glucose homeostasis identical protein binding synapse regulation of sensory perception of pain regulation of retrograde trans-synaptic signaling by endocanabinoid positive regulation of cold-induced thermogenesis	03320
1456341_a_at	Klf9	Kruppel-like transcription factor 9	19	23141225	AV354744	16601	96	RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus nucleoplasm cytosol plasma membrane regulation of DNA-templated transcription regulation of transcription by RNA polymerase II embryo implantation negative regulation of keratinocyte proliferation positive regulation of transcription by RNA polymerase II metal ion binding rhythmic process progesterone receptor signaling pathway cellular response to cortisol stimulus
1421304_at	Klra2	killer cell lectin-like receptor, subfamily A, member 2	6	-131219234	NM_008462	16633	25	plasma membrane cell adhesion membrane carbohydrate binding
1458802_at	Hivep3	human immunodeficiency virus type I enhancer binding protein 3	4	119814677	BB164127	16656	46	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus nucleus cytoplasm cytosol regulation of transcription by RNA polymerase II skeletal muscle cell differentiation positive regulation of DNA-templated transcription metal ion binding
1451716_at	Mafb	MAF bZIP transcription factor B	2	-160363676	AW412521	16658	292	RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II segment specification respiratory gaseous exchange by respiratory system gene expression protein processing rhombomere 5 development rhombomere 6 development abducens nerve formation keratinocyte differentiation T cell differentiation in thymus brain segmentation inner ear morphogenesis identical protein binding sequence-specific DNA binding protein-containing complex binding regulation of myeloid cell differentiation negative regulation of erythrocyte differentiation negative regulation of osteoclast differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II thymus development RNA polymerase II transcription regulator complex cornified envelope assembly sequence-specific double-stranded DNA binding
1455434_a_at	Ktn1	kinectin 1	14	47663755, 47649310	BF162017	16709	36	endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane microtubule-based movement protein transport membrane kinesin binding
1433939_at	Aff3	AF4/FMR2 family, member 3	1	-38175990	BQ177036	16764	39	DNA binding double-stranded DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity nucleus nucleus nucleoplasm cytosol DNA-templated transcription regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of gene expression regulation of gene expression nuclear body super elongation complex response to tumor necrosis factor embryonic hindlimb morphogenesis embryonic hindlimb morphogenesis
1428094_at	Lamp2	lysosomal-associated membrane protein 2	X	-38405048, -38419502, -38399646	BB390704	16784	183	autophagosome membrane protein binding extracellular space lysosome lysosome lysosomal membrane lysosomal membrane lysosomal membrane endosome late endosome late endosome trans-Golgi network plasma membrane plasma membrane protein targeting autophagy lysosomal lumen acidification ion channel inhibitor activity cellular response to starvation cellular response to starvation membrane enzyme binding protein domain specific binding protein catabolic process phagocytic vesicle membrane platelet dense granule membrane negative regulation of protein-containing complex assembly cytoplasmic vesicle regulation of protein stability late endosome membrane late endosome membrane late endosome membrane signaling adaptor activity intracellular membrane-bounded organelle autolysosome membrane raft muscle cell cellular homeostasis perinuclear region of cytoplasm protein stabilization chaperone-mediated autophagy chaperone-mediated autophagy chaperone-mediated autophagy protein targeting to lysosome involved in chaperone-mediated autophagy protein targeting to lysosome involved in chaperone-mediated autophagy protein targeting to lysosome involved in chaperone-mediated autophagy chaperone-mediated autophagy translocation complex extracellular exosome autophagosome maturation autophagosome maturation negative regulation of NLRP3 inflammasome complex assembly lysosomal protein catabolic process lysosomal matrix	04142 04145
1460651_at	Lat	linker for activation of T cells	7	-126363827	AF036907	16797	158	immunological synapse immunological synapse immunological synapse adaptive immune response lymphocyte homeostasis immune system process protein binding Golgi apparatus plasma membrane plasma membrane cell-cell junction inflammatory response inflammatory response immune response immune response cellular defense response signal transduction transmembrane receptor protein tyrosine kinase signaling pathway integrin-mediated signaling pathway Ras protein signal transduction COP9 signalosome gene expression membrane calcium-mediated signaling protein kinase binding protein kinase binding signaling receptor complex adaptor activity intracellular signal transduction intracellular signal transduction mast cell degranulation positive regulation of protein kinase activity homeostasis of number of cells T cell receptor signaling pathway regulation of T cell activation regulation of T cell activation	04650 04660 04664 04666
1421164_a_at	Arhgef1	Rho guanine nucleotide exchange factor 1	7	24902985, 24904345	NM_008488	16801	62	G protein-coupled receptor binding G protein-coupled receptor binding guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity GTPase activator activity protein binding cytoplasm cytoplasm cytosol plasma membrane microtubule depolymerization G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway membrane	04270 04810
1448550_at	Lbp	lipopolysaccharide binding protein	2	158306492	NM_008489	16803	65	lipopolysaccharide binding lipopolysaccharide binding lipopolysaccharide binding leukocyte chemotaxis involved in inflammatory response macrophage activation involved in immune response macrophage activation involved in immune response macrophage activation involved in immune response immune system process cell surface pattern recognition receptor signaling pathway signaling receptor binding extracellular region extracellular space extracellular space extracellular space lipid transport acute-phase response acute-phase response lipid binding cell surface cell surface coreceptor activity lipopolysaccharide transport membrane neutrophil chemotaxis lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway detection of molecule of bacterial origin response to lipopolysaccharide response to lipopolysaccharide tumor necrosis factor production negative regulation of tumor necrosis factor production positive regulation of chemokine production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of toll-like receptor 4 signaling pathway defense response to bacterium positive regulation of macrophage activation positive regulation of macrophage activation innate immune response innate immune response defense response to Gram-negative bacterium defense response to Gram-negative bacterium defense response to Gram-negative bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to Gram-positive bacterium positive regulation of phagocytosis, engulfment positive regulation of respiratory burst involved in inflammatory response lipoteichoic acid binding cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipoteichoic acid lipopeptide binding positive regulation of neutrophil chemotaxis regulation of membrane permeability	04620
1425396_a_at	Lck	lymphocyte protein tyrosine kinase	4	-129548343, -129548343	BC011474	16818	302	nucleotide binding pericentriolar material immunological synapse phosphotyrosine residue binding antigen binding protein kinase activity protein tyrosine kinase activity protein tyrosine kinase activity protein tyrosine kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein serine/threonine phosphatase activity signaling receptor binding protein binding ATP binding cytoplasm cytosol plasma membrane plasma membrane cell-cell junction protein phosphorylation protein phosphorylation protein phosphorylation activation of cysteine-type endopeptidase activity involved in apoptotic process cell surface receptor signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway response to xenobiotic stimulus response to mechanical stimulus response to metal ion positive regulation of gene expression phospholipase activator activity membrane kinase activity phosphorylation transferase activity peptidyl-tyrosine phosphorylation peptidyl-tyrosine phosphorylation protein kinase binding protein phosphatase binding protein phosphatase binding endocytic vesicle T cell differentiation T cell differentiation positive regulation of heterotypic cell-cell adhesion intracellular signal transduction peptidyl-tyrosine autophosphorylation Fc-gamma receptor signaling pathway SH2 domain binding gamma-delta T cell differentiation positive regulation of tyrosine phosphorylation of STAT protein response to hydrogen peroxide T cell receptor binding CD4 receptor binding CD4 receptor binding CD8 receptor binding identical protein binding phospholipase binding phosphatidylinositol 3-kinase binding protein-containing complex binding innate immune response membrane raft positive regulation of gamma-delta T cell differentiation regulation of regulatory T cell differentiation protein autophosphorylation B cell receptor signaling pathway B cell receptor signaling pathway regulation of T cell receptor signaling pathway positive regulation of T cell activation ATPase binding release of sequestered calcium ion into cytosol positive regulation of uterine smooth muscle contraction glutamatergic synapse postsynaptic specialization, intracellular component positive regulation of leukocyte cell-cell adhesion protein antigen binding positive regulation of intrinsic apoptotic signaling pathway	04380 04650 04660 05340
1427747_a_at	Lcn2	lipocalin 2	2	-32384636	X14607	16819	375	protease binding immune system process iron ion binding iron ion binding protein binding extracellular region extracellular region extracellular space extracellular space extracellular space extracellular space cytosol monoatomic ion transport iron ion transport apoptotic process short-term memory long-term memory response to xenobiotic stimulus response to virus response to bacterium response to herbicide positive regulation of endothelial cell migration positive regulation of gene expression siderophore transport siderophore transport positive regulation of cell projection organization cytoplasmic vesicle small molecule binding defense response to bacterium identical protein binding positive regulation of apoptotic process positive regulation of neuron apoptotic process innate immune response cellular response to hydrogen peroxide extrinsic apoptotic signaling pathway in absence of ligand positive regulation of hippocampal neuron apoptotic process negative regulation of hippocampal neuron apoptotic process positive regulation of cold-induced thermogenesis iron ion sequestering activity positive regulation of reactive oxygen species biosynthetic process enterobactin binding positive regulation of iron ion import across plasma membrane positive regulation of endothelial tube morphogenesis positive regulation of reactive oxygen species metabolic process
1452024_a_at	Ldb1	LIM domain binding 1	19	-46032589, -46032589, -46032589	AF030333	16825	137	negative regulation of transcription by RNA polymerase II chromatin transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery gastrulation with mouth forming second hair follicle development DNA binding chromatin binding transcription coactivator activity protein binding nucleus nucleus nucleoplasm transcription regulator complex transcription regulator complex transcription regulator complex transcription regulator complex transcription by RNA polymerase II cell adhesion multicellular organism development nervous system development anterior/posterior axis specification epithelial structure maintenance Wnt signaling pathway enzyme binding enzyme binding cerebellum development cerebellar Purkinje cell differentiation cellular component assembly neuron differentiation LIM domain binding LIM domain binding LIM domain binding LIM domain binding regulation of cell migration cell leading edge positive regulation of transcription elongation by RNA polymerase II protein-containing complex protein-containing complex somatic stem cell population maintenance identical protein binding protein homodimerization activity regulation of kinase activity protein self-association negative regulation of erythrocyte differentiation positive regulation of cell adhesion negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of hemoglobin biosynthetic process regulation of focal adhesion assembly primitive erythrocyte differentiation head development RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II transcription regulator complex DNA-binding transcription factor binding DNA-binding transcription factor binding beta-catenin-TCF complex
1434499_a_at	Ldhb	lactate dehydrogenase B	6	-142490248	AV219418	16832	77	catalytic activity lactate dehydrogenase activity L-lactate dehydrogenase activity L-lactate dehydrogenase activity L-lactate dehydrogenase activity cytoplasm mitochondrion mitochondrion mitochondrial inner membrane cytosol cytosol lactate metabolic process lactate metabolic process pyruvate metabolic process pyruvate metabolic process membrane oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor lactate biosynthetic process from pyruvate NAD metabolic process carboxylic acid metabolic process kinase binding identical protein binding myelin sheath membrane raft NAD binding oxidoreductase complex	00010 00270 00620 00640 01100
1454734_at	Lef1	lymphoid enhancer binding factor 1	3	131110296, 131112790, 131156293, 131110322, 131112790	AV156352	16842	676	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding transcription corepressor binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific branching involved in blood vessel morphogenesis somitogenesis somitogenesis epithelial to mesenchymal transition vasculature development sprouting angiogenesis nucleic acid binding DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex transcription regulator complex transcription regulator complex cytoplasm cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II beta-catenin binding transcription factor binding DNA binding, bending DNA binding, bending positive regulation of gene expression positive regulation of epithelial to mesenchymal transition Wnt signaling pathway dentate gyrus development hippocampus development forebrain radial glial cell differentiation forebrain neuroblast division formation of radial glial scaffolds regulation of cell-cell adhesion regulation of Wnt signaling pathway positive regulation of Wnt signaling pathway neutrophil differentiation embryonic limb morphogenesis nuclear estrogen receptor binding positive regulation of cell migration BMP signaling pathway positive regulation of granulocyte differentiation mammary gland development negative regulation of interleukin-13 production negative regulation of interleukin-4 production negative regulation of interleukin-5 production protein-DNA complex T cell receptor V(D)J recombination B cell proliferation histone binding odontogenesis of dentin-containing tooth odontogenesis of dentin-containing tooth histone deacetylase binding negative regulation of apoptotic process negative regulation of DNA binding sequence-specific DNA binding sequence-specific DNA binding tongue development positive regulation by host of viral transcription T-helper 1 cell differentiation gamma-catenin binding positive regulation of gamma-delta T cell differentiation positive regulation of cell differentiation negative regulation of striated muscle tissue development negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II alpha-beta T cell differentiation paraxial mesoderm formation cell development regulation of neurogenesis sensory perception of taste anatomical structure regression canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway face morphogenesis cell chemotaxis apoptotic process involved in morphogenesis chorio-allantoic fusion trachea gland development secondary palate development armadillo repeat domain binding C2H2 zinc finger domain binding protein localization to chromatin cellular response to cytokine stimulus cellular response to interleukin-4 positive regulation of cell proliferation in bone marrow negative regulation of apoptotic process in bone marrow cell odontoblast differentiation positive regulation of cell cycle process RNA polymerase II transcription regulator complex transcription regulator inhibitor activity positive regulation of odontoblast differentiation apoptotic process involved in blood vessel morphogenesis positive regulation of chondrocyte proliferation epithelial cell apoptotic process sequence-specific double-stranded DNA binding beta-catenin-TCF complex beta-catenin-TCF complex beta-catenin-TCF complex	04310 04520 04916 05200 05210 05213 05215 05216 05217 05221 05412
1426808_at	Lgals3	lectin, galactose binding, soluble 3	14	47373859	X16834	16854	428	skeletal system development cornified envelope immunological synapse immunological synapse immunological synapse immune system process monocyte chemotaxis monocyte chemotaxis protein binding extracellular region extracellular region extracellular space extracellular space extracellular space nucleus nucleus nucleus nucleoplasm spliceosomal complex cytoplasm cytoplasm cytoplasm mitochondrial inner membrane cytosol mRNA processing positive regulation of cell population proliferation RNA splicing external side of plasma membrane cell surface cell surface positive regulation of serotonin secretion IgE binding IgE binding protein phosphatase binding cell differentiation extracellular matrix organization carbohydrate binding neutrophil chemotaxis neutrophil chemotaxis extracellular matrix positive regulation of protein-containing complex assembly killing of cells of another organism Fc-gamma receptor I complex binding chemoattractant activity regulation of T cell proliferation negative regulation of apoptotic process laminin binding laminin binding innate immune response positive regulation of angiogenesis negative regulation of endocytosis negative regulation of endocytosis negative regulation of endocytosis monosaccharide binding disaccharide binding disaccharide binding eosinophil chemotaxis eosinophil chemotaxis macrophage chemotaxis macrophage chemotaxis advanced glycation end-product receptor activity negative regulation of T cell receptor signaling pathway positive chemotaxis positive chemotaxis antimicrobial humoral immune response mediated by antimicrobial peptide collagen-containing extracellular matrix regulation of T cell apoptotic process oligosaccharide binding mononuclear cell migration positive regulation of mononuclear cell migration positive regulation of calcium ion import positive regulation of calcium ion import glial cell projection molecular condensate scaffold activity regulation of extrinsic apoptotic signaling pathway via death domain receptors positive regulation of protein localization to plasma membrane negative regulation of cell proliferation in bone marrow negative regulation of immunological synapse formation negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell negative regulation of extrinsic apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway
1421217_a_at	Lgals9	lectin, galactose binding, soluble 9	11	-78962978	NM_010708	16859	121	positive regulation of cytokine production immune system process signaling receptor binding protein binding extracellular region extracellular region extracellular space nucleus nucleus nucleus cytoplasm cytoplasm cytosol cytosol chemotaxis heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules transforming growth factor beta receptor signaling pathway female pregnancy positive regulation of gene expression negative regulation of gene expression galactoside binding galactoside binding galactoside binding enzyme binding enzyme binding carbohydrate binding carbohydrate binding carbohydrate binding carbohydrate binding response to lipopolysaccharide negative regulation of type II interferon production negative regulation of type II interferon production negative regulation of type II interferon production positive regulation of chemokine production positive regulation of interleukin-1 production positive regulation of interleukin-10 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production negative regulation of natural killer cell activation regulation of natural killer cell differentiation positive regulation of macrophage activation receptor clustering negative regulation of natural killer cell degranulation protein serine/threonine kinase activator activity positive regulation of innate immune response maintenance of protein location positive regulation of regulatory T cell differentiation disaccharide binding negative regulation of inflammatory response positive regulation of oxidoreductase activity positive regulation of SMAD protein signal transduction collagen-containing extracellular matrix cellular response to virus positive regulation of defense response to bacterium positive regulation of T cell migration negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of CD4-positive, alpha-beta T cell proliferation
1454984_at	Lifr	LIF receptor alpha	15	7129571, 7140541, 7129571	AV246615	16880	116	cytokine receptor activity cytokine receptor activity ciliary neurotrophic factor receptor activity leukemia inhibitory factor receptor activity oncostatin-M receptor activity oncostatin-M receptor activity ciliary neurotrophic factor receptor binding ciliary neurotrophic factor receptor binding protein binding extracellular region plasma membrane positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation external side of plasma membrane negative regulation of muscle cell apoptotic process membrane cytokine-mediated signaling pathway cytokine-mediated signaling pathway growth factor binding cytokine binding cytokine binding animal organ regeneration response to cytokine oncostatin-M-mediated signaling pathway receptor complex receptor complex neuron projection morphogenesis leukemia inhibitory factor signaling pathway ciliary neurotrophic factor-mediated signaling pathway	04060 04630
1421262_at	Lipg	lipase, endothelial	18	-74939321	BC020991	16891	61	lipoprotein lipase activity lipoprotein lipase activity phospholipase activity phospholipase activity triglyceride lipase activity extracellular region extracellular space extracellular space early endosome Golgi apparatus lipid metabolic process fatty acid biosynthetic process heparin binding phospholipase A1 activity phospholipase A1 activity cell surface positive regulation of high-density lipoprotein particle clearance lipid catabolic process lipase activity hydrolase activity triglyceride catabolic process positive regulation of cholesterol transport high-density lipoprotein particle remodeling high-density lipoprotein particle remodeling cholesterol homeostasis cholesterol homeostasis reverse cholesterol transport regulation of lipoprotein metabolic process carboxylic ester hydrolase activity phosphatidylserine 1-acylhydrolase activity 1-acyl-2-lysophosphatidylserine acylhydrolase activity phospholipid homeostasis	00561 01100
1423520_at	Lmnb1	lamin B1	18	56707812	AA270173	16906	164	double-stranded DNA binding structural constituent of cytoskeleton structural constituent of cytoskeleton nucleus nucleus nuclear envelope nuclear envelope nuclear envelope nuclear envelope nuclear inner membrane lamin filament nuclear lamina nuclear lamina nuclear lamina nucleoplasm nucleoplasm intermediate filament nuclear envelope organization nuclear envelope organization nuclear migration JUN kinase binding positive regulation of G2/M transition of mitotic cell cycle nuclear matrix nuclear matrix heterochromatin formation nuclear membrane nuclear periphery phospholipase binding positive regulation of JNK cascade nuclear pore localization protein localization to nuclear envelope cellular response to L-glutamate sequence-specific double-stranded DNA binding
1460194_at	Phyh	phytanoyl-CoA hydroxylase	2	4918995	NM_010726	16922	29	fatty acid alpha-oxidation fatty acid alpha-oxidation fatty acid alpha-oxidation catalytic activity protein binding mitochondrion peroxisome peroxisome peroxisomal matrix 2-oxoglutarate metabolic process isoprenoid metabolic process ferrous iron binding oxidoreductase activity 2-oxobutyrate catabolic process carboxylic acid binding L-ascorbic acid binding metal ion binding phytanoyl-CoA dioxygenase activity phytanoyl-CoA dioxygenase activity dioxygenase activity methyl-branched fatty acid metabolic process 9+0 non-motile cilium	04146
1448213_at	Anxa1	annexin A1	19	-20373433	NM_010730	16952	251	cornified envelope cornified envelope neutrophil homeostasis neutrophil homeostasis phosphatidylserine binding adaptive immune response immune system process monocyte chemotaxis regulation of leukocyte migration single-stranded DNA binding single-stranded RNA binding phospholipase inhibitor activity calcium ion binding protein binding phospholipid binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding extracellular region extracellular space nucleus nucleoplasm cytoplasm cytoplasm cytoplasm endosome cytosol cytosol actin filament plasma membrane plasma membrane plasma membrane cilium phagocytosis phagocytosis inflammatory response signal transduction signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger lipid binding regulation of cell shape cell surface myoblast migration involved in skeletal muscle regeneration membrane apical plasma membrane lateral plasma membrane peptide cross-linking phospholipase A2 inhibitor activity actin cytoskeleton organization insulin secretion keratinocyte differentiation positive regulation of vesicle fusion positive regulation of prostaglandin biosynthetic process cytoplasmic vesicle motile cilium mitochondrial membrane DNA duplex unwinding regulation of interleukin-1 production negative regulation of interleukin-8 production positive regulation of interleukin-2 production protein-containing complex positive regulation of neutrophil apoptotic process cellular response to vascular endothelial growth factor stimulus double-stranded DNA helicase activity positive regulation of T cell proliferation neutrophil activation regulation of cell population proliferation sarcolemma mast cell granule identical protein binding cell projection positive regulation of apoptotic process innate immune response positive regulation of T-helper 1 cell differentiation negative regulation of T-helper 2 cell differentiation negative regulation of exocytosis alpha-beta T cell differentiation metal ion binding regulation of hormone secretion calcium-dependent protein binding arachidonic acid secretion negative regulation of protein secretion regulation of inflammatory response localization collagen-containing extracellular matrix extracellular exosome cellular response to hydrogen peroxide prolactin secretion cellular response to glucocorticoid stimulus cellular response to glucocorticoid stimulus cellular response to glucocorticoid stimulus granulocyte chemotaxis positive regulation of cell migration involved in sprouting angiogenesis positive regulation of wound healing synaptic membrane neutrophil clearance positive regulation of G1/S transition of mitotic cell cycle DNA/DNA annealing activity
1448655_at	Lrp1	low density lipoprotein receptor-related protein 1	10	-127538157	NM_008512	16971	382	protease binding astrocyte activation involved in immune response cardiac septum development signaling receptor binding calcium ion binding protein binding nucleus cytoplasm endosome early endosome Golgi apparatus cytoskeleton plasma membrane plasma membrane clathrin-coated pit endocytosis receptor-mediated endocytosis receptor-mediated endocytosis receptor-mediated endocytosis receptor-mediated endocytosis receptor-mediated endocytosis phagocytosis phagocytosis lysosomal transport enzyme-linked receptor protein signaling pathway positive regulation of cytosolic calcium ion concentration protein kinase C-activating G protein-coupled receptor signaling pathway multicellular organism development cholesterol metabolic process external side of plasma membrane negative regulation of gene expression negative regulation of cell-substrate adhesion positive regulation of cholesterol efflux positive regulation of neuron projection development negative regulation of neuron projection development negative regulation of smooth muscle cell migration coreceptor activity membrane basolateral plasma membrane alpha-2 macroglobulin receptor activity clathrin-coated vesicle negative regulation of Wnt signaling pathway dendrite negative regulation of transforming growth factor beta receptor signaling pathway clathrin heavy chain binding positive regulation of protein binding positive regulation of lipid transport regulation of cholesterol transport regulation of phospholipase A2 activity insulin-responsive compartment regulation of actin cytoskeleton organization apolipoprotein binding apolipoprotein binding positive regulation of insulin secretion involved in cellular response to glucose stimulus aorta morphogenesis cargo receptor activity cargo receptor activity cargo receptor activity neuronal cell body negative regulation of apoptotic process receptor complex apoptotic cell clearance negative regulation of neuron apoptotic process cellular lipid catabolic process axonal growth cone protein-containing complex binding apical part of cell positive regulation of axon extension positive regulation of endocytosis metal ion binding perinuclear region of cytoplasm positive regulation of axon extension involved in regeneration positive regulation of collateral sprouting of injured axon positive regulation of phagocytosis positive regulation of protein transport negative regulation of cytosolic calcium ion concentration negative regulation of focal adhesion assembly negative regulation of SMAD protein signal transduction coronary vasculature development chemoattraction of axon positive regulation of ERK1 and ERK2 cascade amyloid-beta clearance amyloid-beta clearance by transcytosis amyloid-beta clearance by transcytosis amyloid-beta clearance by transcytosis amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process amyloid-beta clearance by cellular catabolic process transport across blood-brain barrier positive regulation of Schwann cell migration positive regulation of amyloid-beta clearance positive regulation of protein localization to plasma membrane positive regulation of cholesterol import positive regulation of transcytosis cellular response to amyloid-beta positive regulation of vascular associated smooth muscle cell migration regulation of pulmonary blood vessel remodeling positive regulation of lysosomal protein catabolic process positive regulation of chemokine (C-X-C motif) ligand 2 production negative regulation of platelet-derived growth factor receptor-beta signaling pathway	05010 05144
1419135_at	Ltb	lymphotoxin B	17	35194506	NM_008518	16994	169	cytokine activity tumor necrosis factor receptor binding extracellular space plasma membrane immune response gene expression membrane positive regulation of interleukin-12 production positive regulation of canonical NF-kappaB signal transduction skin development lymph node development positive regulation of extrinsic apoptotic signaling pathway	04060 05323
1420407_at	Ltb4r1	leukotriene B4 receptor 1	14	55765961	NM_008519	16995	143	leukotriene B4 receptor activity leukotriene B4 receptor activity G protein-coupled receptor activity leukotriene receptor activity plasma membrane signal transduction G protein-coupled receptor signaling pathway neuropeptide signaling pathway G protein-coupled peptide receptor activity membrane	04080
1416435_at	Ltbr	lymphotoxin B receptor	6	-125306570	NM_010736	17000	231	protein binding Golgi apparatus plasma membrane apoptotic process immune response membrane ubiquitin protein ligase binding ubiquitin protein ligase binding identical protein binding myeloid dendritic cell differentiation positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of JNK cascade hematopoietic or lymphoid organ development lymph node development positive regulation of extrinsic apoptotic signaling pathway	04060 04672
1450009_at	Ltf	lactotransferrin	9	111019291	NM_008522	17002	112	ossification lipopolysaccharide binding regulation of cytokine production innate immune response in mucosa immune system process serine-type endopeptidase activity cysteine-type endopeptidase inhibitor activity iron ion binding extracellular region extracellular space extracellular space cytoplasm cytoplasm early endosome plasma membrane proteolysis monoatomic ion transport iron ion transport iron ion transport heparin binding peptidase activity serine-type peptidase activity cell surface hydrolase activity antibacterial humoral response antibacterial humoral response antifungal humoral response secretory granule killing of cells of another organism negative regulation of lipopolysaccharide-mediated signaling pathway regulation of tumor necrosis factor production negative regulation of ATP-dependent activity protein-containing complex positive regulation of osteoblast proliferation positive regulation of toll-like receptor 4 signaling pathway specific granule positive regulation of canonical NF-kappaB signal transduction protein serine/threonine kinase activator activity negative regulation by host of viral process negative regulation of viral genome replication innate immune response positive regulation of osteoblast differentiation negative regulation of membrane potential metal ion binding negative regulation of viral process defense response to Gram-negative bacterium defense response to Gram-positive bacterium positive regulation of NF-kappaB transcription factor activity cytolysis by host of symbiont cells recycling endosome bone morphogenesis antimicrobial humoral immune response mediated by antimicrobial peptide positive regulation of protein serine/threonine kinase activity membrane destabilizing activity negative regulation of single-species biofilm formation in or on host organism positive regulation of chondrocyte proliferation negative regulation of cysteine-type endopeptidase activity
1451780_at	Blnk	B cell linker	19	-40928926	AF068182	17060	110	protein binding cytoplasm cytoplasm cytosol plasma membrane transmembrane receptor protein tyrosine kinase signaling pathway lipid binding positive regulation of gene expression membrane enzyme binding protein kinase binding intracellular signal transduction intracellular signal transduction signaling adaptor activity B cell activation SH2 domain binding intracellular membrane-bounded organelle phospholipase binding B cell receptor signaling pathway protein tyrosine kinase binding	04380 04662 05340
1416359_at	Snx18	sorting nexin 18	13	-113592178	AV344473	170625	23	mitotic cell cycle mitotic cytokinesis protein binding phosphatidylinositol-4,5-bisphosphate binding endosome plasma membrane plasma membrane endocytosis endocytosis cell cycle lipid binding cytoplasmic side of plasma membrane protein transport membrane endosomal transport endosomal transport clathrin-coated vesicle growth cone cytoplasmic vesicle cytoplasmic vesicle phosphatidylinositol binding phosphatidylinositol binding cleavage furrow formation cleavage furrow formation neuronal cell body positive regulation of GTPase activity cell division recycling endosome membrane extracellular exosome plasma membrane tubulation positive regulation of autophagosome assembly
1416930_at	Ly6d	lymphocyte antigen 6 family member D	15	-74762055	NM_010742	17068	32	plasma membrane cell surface cell surface membrane lymphocyte differentiation lymphocyte differentiation response to stilbenoid side of membrane
1422041_at	Pilrb1	paired immunoglobin-like type 2 receptor beta 1	5	-137852146	NM_133209	170741	12	myeloid dendritic cell activation protein binding plasma membrane membrane MHC class I protein binding MHC class I protein binding negative regulation of osteoclast differentiation
1426218_at	Glcci1	glucocorticoid induced transcript 1	6	8520057, 8509599	AA152997	170772	34	cytoplasm cytoplasm
1454775_at	Hdac10	histone deacetylase 10	15	-89123302	AW548891	170787	28	histone deacetylase complex negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II histone deacetylase activity nucleus nucleoplasm cytoplasm cytosol DNA repair DNA recombination chromatin organization chromatin remodeling regulation of DNA-templated transcription autophagy DNA damage response macroautophagy hydrolase activity deacetylase activity deacetylase activity enzyme binding positive regulation of mismatch repair peptidyl-lysine deacetylation homologous recombination histone deacetylase binding intracellular membrane-bounded organelle negative regulation of DNA-templated transcription metal ion binding acetylputrescine deacetylase activity acetylspermidine deacetylase activity polyamine deacetylation spermidine deacetylation
1438398_at	Rbm39	RNA binding motif protein 39	2	-156147240, -156147240	BB203348	170791	50	nucleic acid binding RNA binding protein binding nucleus nucleoplasm mRNA processing RNA splicing microtubule cytoskeleton nuclear speck protein-containing complex centriolar satellite regulation of mRNA splicing, via spliceosome RS domain binding U1 snRNP binding
1449874_at	Ly96	lymphocyte antigen 96	1	16688455	NM_016923	17087	127	lipopolysaccharide binding lipopolysaccharide immune receptor activity lipopolysaccharide immune receptor activity toll-like receptor signaling pathway immune system process protein binding extracellular region plasma membrane inflammatory response lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway positive regulation of lipopolysaccharide-mediated signaling pathway positive regulation of lipopolysaccharide-mediated signaling pathway positive regulation of lipopolysaccharide-mediated signaling pathway positive regulation of lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide detection of lipopolysaccharide detection of lipopolysaccharide positive regulation of tumor necrosis factor production toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway Toll-like receptor 4 binding receptor complex innate immune response lipopolysaccharide receptor complex lipopolysaccharide receptor complex lipopolysaccharide receptor complex cellular response to lipopolysaccharide cellular response to lipopolysaccharide	04620 05145
1439200_x_at	Erdr1x	erythroid differentiation regulator 1 x	X, Y	90785441	BE686792	170942	31	molecular_function cellular_component negative regulation of cell population proliferation negative regulation of cell migration somatic stem cell population maintenance
1437540_at	Mcoln3	mucolipin 3	3	146121790	AV313762	171166	55	monoatomic cation channel activity cytoplasm lysosomal membrane endosome plasma membrane plasma membrane monoatomic ion transport sensory perception of sound locomotory behavior lipid binding membrane cytoplasmic vesicle monoatomic ion transmembrane transport inner ear auditory receptor cell differentiation cell projection NAADP-sensitive calcium-release channel activity
1434678_at	Mbnl3	muscleblind like splicing factor 3	X	-51113493	AV306759	171170	31	RNA binding nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytosol mRNA processing multicellular organism development RNA splicing regulation of RNA splicing regulation of RNA splicing negative regulation of myoblast differentiation metal ion binding
1455104_at	Mxd1	MAX dimerization protein 1	6	-86647044	AV228517	17119	49	negative regulation of transcription by RNA polymerase II chromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding protein binding nucleus nucleoplasm mitochondrion cytosol regulation of transcription by RNA polymerase II protein dimerization activity Mad-Max complex
1440162_x_at	Edaradd	EDAR associated via death domain	13	-12471208	BB446560	171211	53	hair follicle development death receptor binding protein binding cytoplasm signal transduction canonical NF-kappaB signal transduction multicellular organism development cell differentiation odontogenesis of dentin-containing tooth trachea gland development positive regulation of non-canonical NF-kappaB signal transduction
1422486_a_at	Smad4	SMAD family member 4	18	-73634790	AK004804	17128	546	negative regulation of transcription by RNA polymerase II chromatin transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific transcription corepressor binding transcription coactivator binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific ovarian follicle development ovarian follicle development osteoblast differentiation branching involved in ureteric bud morphogenesis response to hypoxia in utero embryonic development gastrulation with mouth forming second kidney development epithelial to mesenchymal transition outflow tract septum morphogenesis atrioventricular valve formation epithelial to mesenchymal transition involved in endocardial cushion formation left ventricular cardiac muscle tissue morphogenesis positive regulation of cell proliferation involved in heart valve morphogenesis cardiac septum development brainstem development DNA binding DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding collagen binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex transcription regulator complex cytoplasm cytoplasm centrosome cytosol DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II intracellular iron ion homeostasis transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway spermatogenesis single fertilization gastrulation axon guidance endoderm development mesoderm development cell population proliferation cell population proliferation negative regulation of cell population proliferation male gonad development female gonad development anatomical structure morphogenesis anatomical structure morphogenesis anterior/posterior pattern specification negative regulation of cardiac muscle hypertrophy positive regulation of gene expression epithelial cell migration positive regulation of cardiac muscle cell apoptotic process positive regulation of epithelial to mesenchymal transition neural crest cell differentiation cardiac muscle hypertrophy in response to stress regulation of transforming growth factor beta receptor signaling pathway cell differentiation cell differentiation negative regulation of cell growth BMP signaling pathway BMP signaling pathway BMP signaling pathway positive regulation of transforming growth factor beta receptor signaling pathway filamin binding activin responsive factor complex somite rostral/caudal axis specification regulation of transforming growth factor beta2 production activin receptor signaling pathway protein-containing complex positive regulation of luteinizing hormone secretion positive regulation of luteinizing hormone secretion intracellular signal transduction atrioventricular canal development endothelial cell activation regulation of cell population proliferation regulation of cell population proliferation negative regulation of protein catabolic process embryonic digit morphogenesis identical protein binding identical protein binding protein homodimerization activity sulfate binding sequence-specific DNA binding protein-containing complex binding negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II SMAD binding metal ion binding positive regulation of follicle-stimulating hormone secretion positive regulation of follicle-stimulating hormone secretion mesendoderm development developmental growth neuron fate commitment neuron fate specification tissue morphogenesis sebaceous gland development formation of anatomical boundary regulation of binding regulation of hair follicle development uterus development positive regulation of SMAD protein signal transduction SMAD protein signal transduction SMAD protein signal transduction SMAD protein signal transduction ventricular septum morphogenesis endocardial cell differentiation female gonad morphogenesis RNA polymerase II-specific DNA-binding transcription factor binding secondary palate development interleukin-6-mediated signaling pathway ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade I-SMAD binding I-SMAD binding R-SMAD binding SMAD protein complex heteromeric SMAD protein complex heteromeric SMAD protein complex heteromeric SMAD protein complex cellular response to glucose stimulus response to transforming growth factor beta cellular response to transforming growth factor beta stimulus metanephric mesenchyme morphogenesis nephrogenic mesenchyme morphogenesis seminiferous tubule development negative regulation of canonical Wnt signaling pathway RNA polymerase II transcription regulator complex extrinsic apoptotic signaling pathway positive regulation of extracellular matrix assembly positive regulation of miRNA transcription negative regulation of cardiac myofibril assembly	04110 04310 04350 04520 05200 05210 05212 05220
1443771_x_at	Smad7	SMAD family member 7	18	75367364	BB241324	17131	269	negative regulation of transcription by RNA polymerase II fibrillar center ureteric bud development negative regulation of T cell cytokine production transcription corepressor activity protein binding collagen binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex cytoplasm centrosome cytosol cytosol plasma membrane adherens junction regulation of DNA-templated transcription regulation of transcription by RNA polymerase II transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway beta-catenin binding anatomical structure morphogenesis regulation of epithelial to mesenchymal transition negative regulation of peptidyl-threonine phosphorylation negative regulation of peptidyl-threonine phosphorylation negative regulation of transcription by competitive promoter binding regulation of transforming growth factor beta receptor signaling pathway positive regulation of cell-cell adhesion positive regulation of cell-cell adhesion cell differentiation negative regulation of ossification negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of BMP signaling pathway negative regulation of BMP signaling pathway negative regulation of protein ubiquitination protein-containing complex localization ubiquitin protein ligase binding negative regulation of activin receptor signaling pathway protein-containing complex protein-containing complex negative regulation of peptidyl-serine phosphorylation negative regulation of peptidyl-serine phosphorylation adherens junction assembly type I transforming growth factor beta receptor binding intracellular signal transduction metal ion binding artery morphogenesis protein stabilization negative regulation of ubiquitin-protein transferase activity ventricular cardiac muscle tissue morphogenesis regulation of cardiac muscle contraction regulation of ventricular cardiac muscle cell membrane depolarization negative regulation of SMAD protein signal transduction negative regulation of SMAD protein signal transduction SMAD protein signal transduction ventricular septum morphogenesis I-SMAD binding I-SMAD binding activin receptor binding heteromeric SMAD protein complex cellular response to transforming growth factor beta stimulus cellular response to transforming growth factor beta stimulus transcription regulator inhibitor activity transcription regulator inhibitor activity negative regulation of chondrocyte proliferation positive regulation of chondrocyte hypertrophy ubiquitin ligase-substrate adaptor activity cellular response to leukemia inhibitory factor negative regulation of T-helper 17 type immune response negative regulation of T-helper 17 cell differentiation	04144 04350
1456060_at	Maf	MAF bZIP transcription factor	8	-115703252	AV284857	17132	208	negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific cytokine production lens development in camera-type eye DNA binding double-stranded DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II positive regulation of gene expression megakaryocyte differentiation regulation of chondrocyte differentiation identical protein binding sequence-specific DNA binding protein-containing complex binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II cell development inner ear development lens fiber cell differentiation lens fiber cell differentiation RNA polymerase II transcription regulator complex sequence-specific double-stranded DNA binding
1448647_at	Man2a1	mannosidase 2, alpha 1	17	64601648	NM_008549	17158	42	Golgi membrane Golgi membrane Golgi membrane in utero embryonic development liver development catalytic activity alpha-mannosidase activity alpha-mannosidase activity mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity extracellular space Golgi apparatus Golgi medial cisterna cis-Golgi network carbohydrate metabolic process mannose metabolic process N-glycan processing N-glycan processing N-glycan processing protein deglycosylation mitochondrion organization vacuole organization respiratory gaseous exchange by respiratory system metabolic process mannosidase activity membrane hydrolase activity hydrolase activity, acting on glycosyl bonds hydrolase activity, hydrolyzing N-glycosyl compounds carbohydrate binding identical protein binding protein homodimerization activity metal ion binding lung alveolus development positive regulation of neurogenesis retina morphogenesis in camera-type eye	00510 01100
1456439_x_at	Mical1	microtubule associated monooxygenase, calponin and LIM domain containing 1	10	41476313, 41478009	BB209438	171580	31	negative regulation of protein phosphorylation actin binding actin binding monooxygenase activity monooxygenase activity protein binding cytoplasm endosome cytosol cytoskeleton actin filament endosome membrane membrane NAD(P)H oxidase H2O2-forming activity oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen SH3 domain binding sulfur oxidation protein kinase binding actin filament depolymerization actin filament depolymerization midbody small GTPase binding negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process intercellular bridge metal ion binding FAD binding FAD binding regulation of regulated secretory pathway hippocampal mossy fiber expansion
1449498_at	Marco	macrophage receptor with collagenous structure	1	-120474537	NM_010766	17167	77	amyloid-beta binding G protein-coupled receptor binding immune system process collagen trimer extracellular space cytoplasm plasma membrane plasma membrane endocytosis receptor-mediated endocytosis phagocytosis, engulfment membrane extracellular matrix cargo receptor activity apoptotic cell clearance innate immune response amyloid-beta clearance	04145
1434888_a_at	Matr3	matrin 3	18	35562157	BM219545	17184	73	blastocyst formation activation of innate immune response immune system process heart valve development ventricular septum development nucleic acid binding RNA binding RNA binding nucleus nucleus zinc ion binding post-transcriptional regulation of gene expression nuclear matrix miRNA binding identical protein binding innate immune response metal ion binding
1416881_at	Mcl1	myeloid cell leukemia sequence 1	3	95658720	BC003839	17210	275	release of cytochrome c from mitochondria protein binding nucleus nucleus cytoplasm mitochondrion mitochondrion mitochondrial outer membrane cytosol apoptotic process DNA damage response multicellular organism development mitochondrial fusion intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage negative regulation of autophagy channel activity membrane membrane cell differentiation response to cytokine protein homodimerization activity regulation of apoptotic process positive regulation of apoptotic process positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process protein-containing complex binding protein heterodimerization activity protein heterodimerization activity protein dimerization activity BH domain binding BH3 domain binding BH3 domain binding Bcl-2 family protein complex extrinsic apoptotic signaling pathway in absence of ligand extrinsic apoptotic signaling pathway in absence of ligand extrinsic apoptotic signaling pathway in absence of ligand positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway negative regulation of anoikis negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
1449965_at	Mcpt8	mast cell protease 8	14	-56082163	NM_008572	17231	57	serine-type endopeptidase activity extracellular region extracellular space cytoplasm proteolysis peptidase activity serine-type peptidase activity hydrolase activity intracellular membrane-bounded organelle
1460542_s_at	Mdm4	transformed mouse 3T3 cell double minute 4	1	-132986104, -132986104	BQ173933	17248	142	negative regulation of transcription by RNA polymerase II regulation of heart rate heart valve development atrioventricular valve morphogenesis endocardial cushion morphogenesis ventricular septum development atrial septum development ubiquitin-protein transferase activity protein binding nucleus nucleoplasm positive regulation of cell population proliferation protein ubiquitination transcription repressor complex enzyme binding negative regulation of protein catabolic process negative regulation of apoptotic process negative regulation of DNA-templated transcription metal ion binding regulation of cell cycle protein-containing complex assembly negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	04115
1424852_at	Mef2c	myocyte enhancer factor 2C	13	83504033, 83573606, 83524742, 83523655	BB280300	17260	457	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II MAPK cascade MAPK cascade MAPK cascade transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development osteoblast differentiation osteoblast differentiation neuron migration B cell homeostasis heart looping endochondral ossification endochondral ossification blood vessel remodeling chondrocyte differentiation germinal center formation regulation of germinal center formation response to ischemia primary heart field specification secondary heart field specification outflow tract morphogenesis sinoatrial valve morphogenesis cardiac ventricle formation cardiac ventricle formation DNA binding DNA binding minor groove of adenine-thymine-rich DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytosol regulation of DNA-templated transcription regulation of DNA-templated transcription apoptotic process humoral immune response multicellular organism development nervous system development axon guidance heart development heart development skeletal muscle tissue development muscle cell fate determination learning or memory gene expression positive regulation of cardiac muscle hypertrophy positive regulation of gene expression positive regulation of gene expression positive regulation of gene expression negative regulation of gene expression positive regulation of alkaline phosphatase activity neural crest cell differentiation cardiac muscle hypertrophy in response to stress nuclear speck sarcomere cell differentiation cell differentiation neuron differentiation platelet formation monocyte differentiation negative regulation of ossification melanocyte differentiation positive regulation of bone mineralization positive regulation of B cell proliferation protein-containing complex embryonic heart tube development embryonic heart tube development skeletal muscle cell differentiation skeletal muscle cell differentiation cellular response to trichostatin A B cell proliferation histone deacetylase binding histone deacetylase binding intracellular membrane-bounded organelle positive regulation of MAPK cascade regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of blood vessel endothelial cell migration sequence-specific DNA binding cell fate commitment regulation of megakaryocyte differentiation positive regulation of myoblast differentiation positive regulation of neuron differentiation positive regulation of osteoblast differentiation positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of neurotransmitter secretion protein heterodimerization activity protein dimerization activity regulation of synaptic plasticity positive regulation of skeletal muscle tissue development neuron development cell morphogenesis involved in neuron differentiation embryonic viscerocranium morphogenesis embryonic skeletal system morphogenesis negative regulation of epithelial cell proliferation B cell receptor signaling pathway smooth muscle cell differentiation regulation of synapse assembly regulation of synaptic transmission, glutamatergic cardiac muscle cell differentiation cardiac muscle cell differentiation ventricular cardiac muscle cell differentiation roof of mouth development regulation of synaptic activity positive regulation of cardiac muscle cell proliferation excitatory postsynaptic potential transdifferentiation regulation of sarcomere organization cartilage morphogenesis regulation of dendritic spine development renal tubule morphogenesis RNA polymerase II-specific DNA-binding transcription factor binding cellular response to lipopolysaccharide cellular response to calcium ion cellular response to retinoic acid cellular response to growth factor stimulus cellular response to parathyroid hormone stimulus cellular response to xenobiotic stimulus cellular response to fluid shear stress cellular response to transforming growth factor beta stimulus HMG box domain binding cell proliferation in bone marrow positive regulation of cell proliferation in bone marrow glomerulus morphogenesis nephron tubule epithelial cell differentiation sympathetic neuron axon guidance DNA-binding transcription factor binding semaphorin-plexin signaling pathway involved in axon guidance negative regulation of vascular associated smooth muscle cell proliferation negative regulation of vascular associated smooth muscle cell migration negative regulation of vascular endothelial cell proliferation sequence-specific double-stranded DNA binding positive regulation of macrophage apoptotic process regulation of NMDA receptor activity regulation of AMPA receptor activity positive regulation of cardiac muscle cell differentiation positive regulation of cardiac muscle cell differentiation positive regulation of behavioral fear response epithelial cell proliferation involved in renal tubule morphogenesis positive regulation of skeletal muscle cell differentiation	04010
1434487_at	Mef2d	myocyte enhancer factor 2D	3	88142371	AV334508	17261	130	RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific osteoblast differentiation endochondral ossification chondrocyte differentiation DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytoplasm regulation of DNA-templated transcription apoptotic process multicellular organism development nervous system development enzyme binding cell differentiation cell differentiation skeletal muscle cell differentiation protein homodimerization activity histone deacetylase binding histone deacetylase binding intracellular membrane-bounded organelle positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein heterodimerization activity protein dimerization activity RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription factor binding positive regulation of vascular associated smooth muscle cell proliferation sequence-specific double-stranded DNA binding
1422869_at	Mertk	MER proto-oncogene tyrosine kinase	2	128698914	NM_008587	17289	238	nucleotide binding photoreceptor outer segment natural killer cell differentiation negative regulation of cytokine production protein kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity ATP binding extracellular space cytoplasm plasma membrane protein phosphorylation phagocytosis phagocytosis transmembrane receptor protein tyrosine kinase signaling pathway multicellular organism development spermatogenesis nervous system development membrane kinase activity phosphorylation cell migration transferase activity platelet activation secretion by cell positive regulation of kinase activity substrate adhesion-dependent cell spreading receptor complex apoptotic cell clearance apoptotic cell clearance apoptotic cell clearance lymphocyte activation positive regulation of phagocytosis negative regulation of lymphocyte activation establishment of localization in cell positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction retina development in camera-type eye vagina development neutrophil clearance negative regulation of leukocyte apoptotic process
1434447_at	Met	met proto-oncogene	6	17463956	BG060788	17295	431	negative regulation of transcription by RNA polymerase II nucleotide binding neuron migration endothelial cell morphogenesis liver development liver development placenta development protein kinase activity protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity hepatocyte growth factor receptor activity hepatocyte growth factor receptor activity hepatocyte growth factor receptor activity protein binding ATP binding extracellular space protein phosphorylation phagocytosis transmembrane receptor protein tyrosine kinase signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway chemical synaptic transmission multicellular organism development nervous system development brain development muscle organ development muscle organ development skeletal muscle tissue development beta-catenin binding basal plasma membrane basal plasma membrane positive regulation of gene expression negative regulation of gene expression positive regulation of peptidyl-threonine phosphorylation negative regulation of peptidyl-threonine phosphorylation positive regulation of glucose transmembrane transport positive regulation of neuron projection development muscle cell migration myotube differentiation membrane kinase activity phosphorylation cell migration transferase activity semaphorin receptor activity protein phosphatase binding neuron differentiation flagellated sperm motility dendrite adult behavior pancreas development positive regulation of microtubule polymerization regulation of interleukin-6 production positive regulation of peptidyl-serine phosphorylation positive regulation of kinase activity negative regulation of Rho protein signal transduction sperm flagellum glucose homeostasis identical protein binding neuronal cell body receptor complex phospholipase binding positive regulation of MAPK cascade phosphatidylinositol 3-kinase binding protein-containing complex binding postsynaptic membrane positive regulation of DNA replication positive regulation of mitotic nuclear division positive regulation of transcription by RNA polymerase II protein autophosphorylation hepatocyte growth factor receptor signaling pathway branching morphogenesis of an epithelial tube positive regulation of dendrite morphogenesis modulation of chemical synaptic transmission positive chemotaxis positive chemotaxis myoblast proliferation negative regulation of stress fiber assembly establishment of localization in cell cardiac muscle cell development cardiac muscle contraction excitatory synapse excitatory postsynaptic potential regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling establishment of skin barrier negative regulation of thrombin-activated receptor signaling pathway semaphorin-plexin signaling pathway semaphorin-plexin signaling pathway negative regulation of transforming growth factor beta production reactive oxygen species metabolic process molecular function activator activity regulation of cellular response to oxidative stress positive regulation of p38MAPK cascade negative regulation of hydrogen peroxide-mediated programmed cell death glucose transmembrane transport negative regulation of guanyl-nucleotide exchange factor activity positive regulation of endothelial cell chemotaxis	04060 04144 04360 04510 04520 05100 05144 05200 05211 05218
1418652_at	Cxcl9	C-X-C motif chemokine ligand 9	5	-92321330	NM_008599	17329	136	cytokine activity extracellular region extracellular space extracellular space chemotaxis defense response inflammatory response inflammatory response immune response adenylate cyclase-activating G protein-coupled receptor signaling pathway chemokine activity chemokine activity response to bacterium external side of plasma membrane neutrophil chemotaxis killing of cells of another organism regulation of cell population proliferation CXCR chemokine receptor binding positive regulation of myoblast differentiation CXCR3 chemokine receptor binding positive regulation of release of sequestered calcium ion into cytosol defense response to virus antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide chemokine-mediated signaling pathway cellular response to lipopolysaccharide positive regulation of myoblast fusion	04060 04062 04620
1455214_at	Mitf	melanogenesis associated transcription factor	6	97991782, 97929816, 97807057	BB763517	17342	528	negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleus cytoplasm lysosome lysosomal membrane DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II multicellular organism development regulation of gene expression positive regulation of gene expression membrane Wnt signaling pathway cell differentiation osteoclast differentiation melanocyte differentiation melanocyte differentiation melanocyte differentiation negative regulation of cell migration protein-containing complex regulation of cell population proliferation camera-type eye development negative regulation of apoptotic process pigmentation pigmentation sequence-specific DNA binding cell fate commitment regulation of osteoclast differentiation regulation of osteoclast differentiation positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II bone remodeling protein dimerization activity protein-containing complex assembly E-box binding E-box binding melanocyte apoptotic process positive regulation of DNA-templated transcription initiation regulation of RNA biosynthetic process	04380 04916 05200 05218
1428725_at	Pias2	protein inhibitor of activated STAT 2	18	77065679, 77065679, 77065207, 77065207	AK018146	17344	71	DNA binding transcription coregulator activity protein binding nucleus nucleus nucleoplasm nucleoplasm DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II zinc ion binding PML body transferase activity protein sumoylation protein sumoylation protein sumoylation SUMO transferase activity SUMO transferase activity SUMO transferase activity protein domain specific binding nuclear estrogen receptor binding androgen receptor signaling pathway ubiquitin protein ligase binding nuclear glucocorticoid receptor binding negative regulation of DNA-binding transcription factor activity positive regulation of DNA-templated transcription metal ion binding nuclear androgen receptor binding positive regulation of dendrite morphogenesis regulation of androgen receptor signaling pathway negative regulation of androgen receptor signaling pathway RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II-specific DNA-binding transcription factor binding SUMO ligase activity SUMO ligase activity	04120 04630 05160 05200 05222
1437226_x_at	Marcksl1	MARCKS-like 1	4	129513580	AV110584	17357	52	actin binding calmodulin binding cytoplasm cytoplasm cytoskeleton plasma membrane plasma membrane actin filament organization central nervous system development synaptic vesicle cell population proliferation positive regulation of cell population proliferation membrane presynaptic membrane actin filament binding regulation of presynaptic cytosolic calcium ion concentration presynaptic cytosol	04666 05140
1448383_at	Mmp14	matrix metallopeptidase 14 (membrane-inserted)	14	54431597	NM_008608	17387	234	skeletal system development ossification endochondral ossification endopeptidase activity metalloendopeptidase activity metalloendopeptidase activity metalloendopeptidase activity integrin binding extracellular space extracellular space nucleus cytoplasm cytosol plasma membrane plasma membrane proteolysis peptidase activity metallopeptidase activity zinc ion binding response to hormone positive regulation of myotube differentiation positive regulation of protein processing membrane cell migration hydrolase activity extracellular matrix organization positive regulation of cell growth lung development positive regulation of cell migration collagen catabolic process collagen catabolic process extracellular matrix cytoplasmic vesicle zymogen activation zymogen activation zymogen activation chondrocyte proliferation macropinosome intermediate filament cytoskeleton positive regulation of B cell differentiation negative regulation of Notch signaling pathway metal ion binding embryonic cranial skeleton morphogenesis branching morphogenesis of an epithelial tube tissue remodeling negative regulation of focal adhesion assembly head development bone development metalloaminopeptidase activity craniofacial suture morphogenesis regulation of protein localization to plasma membrane positive regulation of macrophage migration	04912
1449366_at	Mmp8	matrix metallopeptidase 8	9	7558428	NM_008611	17394	102	endopeptidase activity endopeptidase activity metalloendopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity calcium ion binding extracellular region extracellular space extracellular space extracellular space proteolysis peptidase activity metallopeptidase activity zinc ion binding hydrolase activity protein catabolic process extracellular matrix organization collagen catabolic process collagen catabolic process extracellular matrix positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production tumor necrosis factor binding metal ion binding cellular response to lipopolysaccharide cellular response to lipopolysaccharide positive regulation of neuroinflammatory response positive regulation of neuroinflammatory response positive regulation of tumor necrosis factor-mediated signaling pathway positive regulation of microglial cell activation
1448291_at	Mmp9	matrix metallopeptidase 9	2	164948218	NM_013599	17395	1127	skeletal system development skeletal system development positive regulation of protein phosphorylation fibronectin binding positive regulation of leukocyte migration endopeptidase activity metalloendopeptidase activity metalloendopeptidase activity metalloendopeptidase activity serine-type endopeptidase activity extracellular region extracellular space extracellular space proteolysis apoptotic process response to oxidative stress heart development embryo implantation peptidase activity peptidase activity metallopeptidase activity zinc ion binding response to xenobiotic stimulus cell migration hydrolase activity protein catabolic process extracellular matrix organization extracellular matrix organization extracellular matrix organization collagen catabolic process collagen catabolic process collagen catabolic process extracellular matrix positive regulation of synaptic plasticity protein-containing complex cellular response to reactive oxygen species identical protein binding positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of DNA binding protein-containing complex binding positive regulation of epidermal growth factor receptor signaling pathway positive regulation of angiogenesis metal ion binding negative regulation of fibroblast proliferation macrophage chemotaxis tissue remodeling positive regulation of keratinocyte migration collagen-containing extracellular matrix cellular response to cadmium ion cellular response to cell-matrix adhesion cellular response to UV-A positive regulation of release of cytochrome c from mitochondria positive regulation of receptor binding response to amyloid-beta positive regulation of vascular associated smooth muscle cell proliferation negative regulation of epithelial cell differentiation involved in kidney development negative regulation of intrinsic apoptotic signaling pathway negative regulation of cation channel activity negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	04670 05200 05219
1448788_at	Cd200	CD200 molecule	16	-45382134	AF004023	17470	116	protein binding plasma membrane negative regulation of cell population proliferation cell surface cell surface cell surface membrane axon axon negative regulation of NF-kappaB transcription factor activity negative regulation of interleukin-6 production positive regulation of CREB transcription factor activity heterotypic cell-cell adhesion heterotypic cell-cell adhesion neuron projection neuronal cell body neuronal cell body negative regulation of macrophage activation cell body regulation of immune response positive regulation of transforming growth factor beta production protein binding involved in heterotypic cell-cell adhesion cell-cell adhesion cell-cell adhesion mediator activity cell-cell adhesion mediator activity positive regulation of arginase activity positive regulation of protein-glutamine gamma-glutamyltransferase activity regulation of neuroinflammatory response negative regulation of neuroinflammatory response negative regulation of neuroinflammatory response negative regulation of neuroinflammatory response negative regulation of matrix metallopeptidase secretion negative regulation of macrophage migration negative regulation of T cell migration
1416915_at	Msh6	mutS homolog 6	17	87975049	U42190	17688	81	nucleotide binding magnesium ion binding four-way junction DNA binding chromatin DNA binding DNA binding chromatin binding damaged DNA binding damaged DNA binding double-stranded DNA binding ATP binding nucleus nucleus nucleoplasm chromosome Golgi apparatus cytosol DNA repair mismatch repair mismatch repair mismatch repair mismatch repair DNA damage response ATP-dependent activity, acting on DNA determination of adult lifespan intrinsic apoptotic signaling pathway in response to DNA damage response to UV somatic hypermutation of immunoglobulin genes somatic recombination of immunoglobulin gene segments enzyme binding mismatched DNA binding mismatched DNA binding guanine/thymine mispair binding guanine/thymine mispair binding single guanine insertion binding single thymine insertion binding MutSalpha complex MutSalpha complex MutSalpha complex oxidized purine DNA binding MutLalpha complex binding methylated histone binding intracellular membrane-bounded organelle ADP binding isotype switching isotype switching negative regulation of DNA recombination negative regulation of DNA recombination positive regulation of helicase activity intrinsic apoptotic signaling pathway ATP-dependent DNA damage sensor activity	03430 05200 05210
1422557_s_at	Mt1	metallothionein 1	8	94179088	NM_013602	17748	343	copper ion binding nucleus nucleus cytoplasm cytoplasm lysosome cytosol cytosol intracellular zinc ion homeostasis intracellular zinc ion homeostasis nitric oxide mediated signal transduction zinc ion binding zinc ion binding detoxification of copper ion detoxification of copper ion intracellular monoatomic cation homeostasis negative regulation of neuron apoptotic process metal ion binding metal ion binding cellular response to chromate cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion cellular response to zinc ion
1428942_at	Mt2	metallothionein 2	8	94172617	AA796766	17750	223	nucleus nucleus cytoplasm cytoplasm cytosol intracellular zinc ion homeostasis intracellular zinc ion homeostasis nitric oxide mediated signal transduction zinc ion binding zinc ion binding response to bacterium detoxification of copper ion detoxification of copper ion cadmium ion binding metal ion binding metal ion binding cellular response to cadmium ion cellular response to copper ion cellular response to zinc ion
1419254_at	Mthfd2	methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase	6	-83305703	BG076333	17768	45	magnesium ion binding catalytic activity methenyltetrahydrofolate cyclohydrolase activity methenyltetrahydrofolate cyclohydrolase activity methenyltetrahydrofolate cyclohydrolase activity methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NAD+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity methylenetetrahydrofolate dehydrogenase (NADP+) activity mitochondrion mitochondrion mitochondrion one-carbon metabolic process metabolic process oxidoreductase activity hydrolase activity tetrahydrofolate interconversion phosphate ion binding tetrahydrofolate metabolic process	00670 01100
1451905_a_at	Mx1	MX dynamin-like GTPase 1	16	-97447036, -97447034	M21039	17857	124	GTPase activity protein binding GTP binding GTP binding nucleus nucleus nuclear pore cytoplasm cytosol response to virus nuclear membrane identical protein binding innate immune response perinuclear region of cytoplasm
1450194_a_at	Myb	myeloblastosis oncogene	10	-21124929	NM_033597	17863	343	G1/S transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II mitotic cell cycle RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific in utero embryonic development DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm cytosol cytosol regulation of DNA-templated transcription regulation of DNA-templated transcription calcium ion transport regulation of gene expression stem cell division myeloid cell differentiation B cell differentiation erythrocyte differentiation positive regulation of collagen biosynthetic process positive regulation of neuron apoptotic process T-helper 2 cell differentiation negative regulation of megakaryocyte differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II spleen development thymus development embryonic digestive tract development positive regulation of smooth muscle cell proliferation homeostasis of number of cells positive regulation of glial cell proliferation myeloid cell development cellular response to interleukin-6 positive regulation of transforming growth factor beta production WD40-repeat domain binding RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex negative regulation of hematopoietic progenitor cell differentiation positive regulation of miRNA transcription positive regulation of hepatic stellate cell proliferation cellular response to leukemia inhibitory factor positive regulation of hepatic stellate cell activation positive regulation of testosterone secretion
1419272_at	Myd88	myeloid differentiation primary response gene 88	9	-119335933	BC005591	17874	2408	response to molecule of fungal origin leukocyte activation involved in inflammatory response neutrophil activation involved in immune response immune system process MyD88-dependent toll-like receptor signaling pathway MyD88-dependent toll-like receptor signaling pathway signaling receptor binding Toll binding interleukin-1 receptor binding interleukin-1 receptor binding protein binding nucleus cytoplasm cytoplasm cytosol plasma membrane plasma membrane plasma membrane chromatin organization phagocytosis phagocytosis apoptotic process inflammatory response immune response signal transduction cell surface receptor signaling pathway transmembrane receptor protein serine/threonine kinase signaling pathway JNK cascade JNK cascade Toll signaling pathway Toll signaling pathway response to virus induced systemic resistance cell surface gene expression regulation of gene expression positive regulation of gene expression positive regulation of gene expression macrophage cytokine production macrophage cytokine production microglia differentiation immunoglobulin mediated immune response cytokine-mediated signaling pathway extrinsic component of plasma membrane neurogenesis extrinsic component of cytoplasmic side of plasma membrane lipopolysaccharide-mediated signaling pathway positive regulation of type I interferon production response to peptidoglycan response to lipopolysaccharide response to lipopolysaccharide chemokine production type I interferon production interleukin-6 production tumor necrosis factor production tumor necrosis factor production regulation of interleukin-6 production regulation of tumor necrosis factor production positive regulation of chemokine production positive regulation of interleukin-1 beta production positive regulation of interleukin-17 production positive regulation of interleukin-23 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production protein-containing complex toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway toll-like receptor 8 signaling pathway Toll-like receptor binding Toll-like receptor binding signaling adaptor activity signaling adaptor activity interleukin-33-mediated signaling pathway regulation of cell population proliferation defense response to bacterium identical protein binding defense response to protozoan positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction skin development protein self-association innate immune response innate immune response positive regulation of transcription by RNA polymerase II positive regulation of JNK cascade positive regulation of smooth muscle cell proliferation positive regulation of lymphocyte proliferation regulation of inflammatory response defense response to Gram-positive bacterium defense response to Gram-positive bacterium positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity defense response to virus molecular adaptor activity type I interferon-mediated signaling pathway positive regulation of macrophage cytokine production positive regulation of macrophage cytokine production interleukin-1-mediated signaling pathway interleukin-1-mediated signaling pathway response to interleukin-1 3'-UTR-mediated mRNA stabilization neutrophil-mediated killing of bacterium TIR domain binding cellular response to lipopolysaccharide cellular response to organic substance establishment of endothelial intestinal barrier cellular response to oxidised low-density lipoprotein particle stimulus ATP-dependent histone chaperone activity positive regulation of cytokine production involved in inflammatory response positive regulation of cytokine production involved in inflammatory response positive regulation of NLRP3 inflammasome complex assembly regulation of neutrophil migration regulation of chemokine (C-X-C motif) ligand 1 production regulation of chemokine (C-X-C motif) ligand 2 production	04210 04620 05140 05142 05143 05144 05145
1422580_at	Myl4	myosin, light polypeptide 4	11	104577280, 104550662, 104576984	NM_010858	17896	93	regulation of the force of heart contraction actin monomer binding actin monomer binding calcium ion binding myosin complex myosin II complex A band A band positive regulation of ATP-dependent activity actin filament binding cardiac muscle contraction cardiac muscle contraction
1449550_at	Myo1c	myosin IC	11	75656014, 75651508, 75652149, 75650518	NM_008659	17913	86	microfilament motor activity microfilament motor activity microfilament motor activity nucleotide binding cytoskeletal motor activity actin binding signaling receptor binding protein binding calmodulin binding calmodulin binding ATP binding phospholipid binding nucleus nucleolus cytoplasm cytoplasm cytosol plasma membrane plasma membrane plasma membrane microvillus microvillus brush border chromatin remodeling protein targeting to membrane endocytosis actin filament organization basal plasma membrane actin cytoskeleton membrane membrane lateral plasma membrane myosin complex nuclear body actin filament-based movement vesicle transport along actin filament positive regulation of cell migration cytoplasmic vesicle membrane positive regulation of actin filament polymerization small GTPase binding cytoplasmic vesicle filamentous actin stereocilium stereocilium bundle ruffle membrane positive regulation of cell migration by vascular endothelial growth factor signaling pathway cell projection membrane raft phagocytic vesicle positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase III actin filament binding actin filament binding cellular response to type II interferon positive regulation of protein targeting to membrane positive regulation of protein targeting to membrane positive regulation of protein targeting to membrane B-WICH complex positive regulation of cellular response to insulin stimulus positive regulation of cellular response to insulin stimulus positive regulation of cellular response to insulin stimulus positive regulation of vascular endothelial growth factor signaling pathway regulation of bicellular tight junction assembly
1460273_a_at	Naip2	NLR family, apoptosis inhibitory protein 2	13	-100144062	NM_010872	17948	26	nucleotide binding immune system process protein binding ATP binding ATP binding apoptotic process inflammatory response inflammatory response negative regulation of tumor necrosis factor-mediated signaling pathway detection of bacterium detection of bacterium defense response to bacterium defense response to bacterium regulation of apoptotic process neuronal cell body cysteine-type endopeptidase inhibitor activity involved in apoptotic process cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process perikaryon innate immune response positive regulation of JNK cascade metal ion binding pyroptosis pyroptosis cellular response to estrogen stimulus IPAF inflammasome complex IPAF inflammasome complex protein serine/threonine kinase binding	04621
1425609_at	Ncf1	neutrophil cytosolic factor 1	5	-134220258, -134220052	BE370703	17969	363	response to yeast leukocyte mediated cytotoxicity respiratory burst involved in defense response protein binding cytoplasm cytoplasm cytosol cytosol plasma membrane leukotriene metabolic process NADP catabolic process smooth muscle contraction inflammatory response cellular defense response lipid binding response to bacterium cytoplasmic side of plasma membrane membrane membrane superoxide-generating NAD(P)H oxidase activity superoxide-generating NADPH oxidase activator activity superoxide-generating NADPH oxidase activator activity superoxide-generating NADPH oxidase activator activity superoxide-generating NADPH oxidase activator activity SH3 domain binding dendrite phosphatidylinositol binding superoxide anion generation superoxide anion generation defense response to bacterium NADPH oxidase complex NADPH oxidase complex neuronal cell body phosphatidylinositol-3,4-bisphosphate binding respiratory burst respiratory burst respiratory burst negative regulation of smooth muscle contraction hydrogen peroxide biosynthetic process epithelial cell proliferation defense response to Gram-positive bacterium defense response to fungus regulation of respiratory burst involved in inflammatory response neutrophil-mediated killing of gram-positive bacterium neutrophil-mediated killing of fungus reactive oxygen species biosynthetic process	04062 04145 04380 04666 04670 05140
1418465_at	Ncf4	neutrophil cytosolic factor 4	15	78244810	NM_008677	17972	42	protein binding cytoplasm cytoplasm endosome cytosol phagocytosis lipid binding endosome membrane membrane superoxide-generating NADPH oxidase activator activity superoxide-generating NADPH oxidase activator activity phosphatidylinositol-3-phosphate binding phosphatidylinositol binding superoxide anion generation superoxide anion generation NADPH oxidase complex NADPH oxidase complex respiratory burst	04145 04380 04670 05140
1428479_at	Nfatc1	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1	18	-80606204, -80647434, -80647434, -80606204	BB356861	18018	536	G1/S transition of mitotic cell cycle negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription coactivator binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific cytokine production epithelial to mesenchymal transition lymphangiogenesis B-1a B cell differentiation heart valve development aortic valve development pulmonary valve development heart valve morphogenesis aortic valve morphogenesis pulmonary valve morphogenesis endocardial cushion development nucleic acid binding DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm transcription regulator complex transcription regulator complex cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II calcium ion transport heart development transcription factor binding gene expression positive regulation of gene expression negative regulation of keratinocyte proliferation transition between fast and slow fiber sarcoplasm nuclear body osteoclast differentiation calcineurin-NFAT signaling cascade calcineurin-NFAT signaling cascade calcineurin-NFAT signaling cascade intracellular signal transduction wound healing regulation of hair cycle sequence-specific DNA binding keratinocyte proliferation cell quiescence negative regulation of osteoblast differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II mitogen-activated protein kinase p38 binding perinuclear region of cytoplasm ventricular septum morphogenesis branching involved in lymph vessel morphogenesis heart trabecula morphogenesis RNA polymerase II-specific DNA-binding transcription factor binding cellular response to calcium ion stem cell proliferation DNA-binding transcription factor binding negative regulation of vascular associated smooth muscle cell differentiation semi-lunar valve development sequence-specific double-stranded DNA binding positive regulation of DNA biosynthetic process negative regulation of stem cell proliferation	04310 04360 04370 04380 04650 04660 04662
1434836_at	Nfatc2ip	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein	7	-126382853	AV277440	18020	29	cytokine production cytokine production protein binding nucleus cytoplasm positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II
1419976_s_at	Nfatc3	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3	8	106059589, 106058817	C79787	18021	160	transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific branching involved in blood vessel morphogenesis response to hypoxia cytokine production blood vessel remodeling DNA binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm transcription regulator complex cytoplasm cytoplasm cytosol cytosol regulation of DNA-templated transcription regulation of transcription by RNA polymerase II transcription by RNA polymerase II multicellular organism development heart development transcription factor binding transcription factor binding cardiac muscle hypertrophy in response to stress myotube differentiation myotube cell development T cell differentiation calcineurin-NFAT signaling cascade calcineurin-NFAT signaling cascade vascular associated smooth muscle cell differentiation sequence-specific DNA binding positive thymic T cell selection cellular respiration positive regulation of nitric oxide biosynthetic process positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II thymus development skeletal muscle fiber development cellular response to calcium ion cellular response to lithium ion vascular associated smooth muscle cell development negative regulation of miRNA transcription DN4 thymocyte differentiation negative regulation of vascular associated smooth muscle cell differentiation positive regulation of artery morphogenesis sequence-specific double-stranded DNA binding regulation of store-operated calcium entry	04310 04360 04370 04650 04660 04662
1416543_at	Nfe2l2	nuclear factor, erythroid derived 2, like 2	2	-75675512, -75691051	NM_010902	18024	1716	chromatin transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific transcription coregulator binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex cytoplasm cytoplasm cytoplasm cytoplasm Golgi apparatus centrosome cytosol cytosol cytosol plasma membrane regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II inflammatory response response to oxidative stress transcription factor binding response to organic substance proteasomal ubiquitin-independent protein catabolic process positive regulation of gene expression positive regulation of gene expression negative regulation of cardiac muscle cell apoptotic process positive regulation of neuron projection development protein ubiquitination protein domain specific binding positive regulation of blood coagulation endoplasmic reticulum unfolded protein response ubiquitin protein ligase binding protein-DNA complex cellular response to oxidative stress cellular response to oxidative stress cellular response to oxidative stress response to endoplasmic reticulum stress PERK-mediated unfolded protein response cellular response to glucose starvation proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of blood vessel endothelial cell migration sequence-specific DNA binding sequence-specific DNA binding regulation of innate immune response cell redox homeostasis cell redox homeostasis positive regulation of angiogenesis positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of embryonic development aflatoxin catabolic process positive regulation of glucose import RNA polymerase II-specific DNA-binding transcription factor binding cellular response to hydrogen peroxide cellular response to copper ion cellular response to tumor necrosis factor cellular response to hypoxia cellular response to xenobiotic stimulus cellular response to fluid shear stress cellular response to laminar fluid shear stress RNA polymerase II transcription regulator complex negative regulation of cellular response to hypoxia regulation of cellular response to oxidative stress negative regulation of hematopoietic stem cell differentiation negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway positive regulation of glutathione biosynthetic process cellular response to angiotensin negative regulation of vascular associated smooth muscle cell migration regulation of removal of superoxide radicals negative regulation of endothelial cell apoptotic process positive regulation of reactive oxygen species metabolic process	04141
1418932_at	Nfil3	nuclear factor, interleukin 3, regulated	13	-52967208	AY061760	18030	130	negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific natural killer cell differentiation DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus DNA-templated transcription regulation of DNA-templated transcription regulation of DNA-templated transcription transcription by RNA polymerase II immune response circadian rhythm circadian rhythm positive regulation of gene expression positive regulation of gene expression identical protein binding negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription rhythmic process cellular response to interleukin-4 RNA polymerase II transcription regulator complex
1418722_at	Ngp	neutrophilic granule protein	9	110419807	NM_008694	18054	22	cysteine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity extracellular region extracellular space extracellular space defense response negative regulation of peptidase activity negative regulation of angiogenesis peptidase inhibitor activity cytoplasmic vesicle negative regulation of lymphangiogenesis
1448465_at	Nipsnap1	nipsnap homolog 1	11	4873950	BC010837	18082	31	protein binding protein binding mitochondrion mitochondrion mitochondrion mitochondrial inner membrane membrane sensory perception of pain sensory perception of pain synaptic membrane
1456573_x_at	Nnt	nicotinamide nucleotide transhydrogenase	13	-119335526, -119334316	BB205930	18115	75	negative regulation of protein phosphorylation mitochondrion mitochondrion mitochondrial inner membrane NADPH regeneration NADPH regeneration NAD(P)+ transhydrogenase activity NAD(P)+ transhydrogenase activity positive regulation of mitochondrial membrane potential membrane oxidoreductase activity intracellular oxygen homeostasis negative regulation of apoptotic process cell redox homeostasis NADP binding NADP binding reactive oxygen species metabolic process cellular oxidant detoxification proton transmembrane transport positive regulation of hydrogen peroxide catabolic process	00760 01100
1426851_a_at	Ccn3	cellular communication network factor 3	15	54745909	X96585	18133	75	angiogenesis chondrocyte differentiation chondrocyte differentiation Notch binding integrin binding integrin binding extracellular region extracellular space extracellular space cytoplasm gap junction cell adhesion signal transduction signal transduction growth factor activity heparin binding regulation of gene expression fibroblast migration negative regulation of myotube differentiation smooth muscle cell migration negative regulation of cell growth axon dendrite extracellular matrix cell adhesion mediated by integrin endothelial cell chemotaxis neuronal cell body intracellular membrane-bounded organelle type B pancreatic cell proliferation positive regulation of cell differentiation positive regulation of Notch signaling pathway negative regulation of insulin secretion smooth muscle cell proliferation smooth muscle cell proliferation negative regulation of inflammatory response cell chemotaxis negative regulation of SMAD protein signal transduction hematopoietic stem cell homeostasis collagen-containing extracellular matrix anchoring junction endothelial cell-cell adhesion negative regulation of monocyte chemotaxis negative regulation of non-canonical NF-kappaB signal transduction negative regulation of chondrocyte proliferation negative regulation of sensory perception of pain bone regeneration
1415839_a_at	Npm1	nucleophosmin 1	11	-33152497, -33154924	NM_008722	18148	183	ribosomal subunit export from nucleus ribosomal large subunit export from nucleus ribosomal large subunit export from nucleus ribosomal small subunit export from nucleus ribosomal small subunit export from nucleus cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) core promoter sequence-specific DNA binding regulation of cell growth granular component p53 binding nucleic acid binding DNA binding chromatin binding transcription coactivator activity RNA binding RNA binding RNA binding protein kinase inhibitor activity protein binding ATP binding phosphatidylinositol-3,4,5-trisphosphate binding nucleus nucleus nucleoplasm nucleoplasm nucleoplasm nucleolus nucleolus nucleolus cytoplasm cytoplasm cytoplasm centrosome centrosome centrosome cytosol cytoskeleton DNA repair nucleosome assembly chromatin remodeling cell volume homeostasis cell volume homeostasis nucleocytoplasmic transport nucleocytoplasmic transport centrosome cycle protein localization protein localization positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation rRNA transcription post-transcriptional regulation of gene expression negative regulation of gene expression negative regulation of cardiac muscle cell apoptotic process regulation of centrosome duplication regulation of centrosome duplication positive regulation of centrosome duplication negative regulation of centrosome duplication large ribosomal subunit small ribosomal subunit nuclear matrix nuclear speck rRNA binding rRNA binding enzyme binding protein kinase binding Tat protein binding positive regulation of cellular biosynthetic process positive regulation of cellular biosynthetic process positive regulation of protein ubiquitination spindle pole centrosome regulation of protein stability protein destabilization regulation of endodeoxyribonuclease activity protein-containing complex protein-DNA complex cellular response to UV ribosomal large subunit biogenesis ribosomal large subunit biogenesis ribosomal large subunit biogenesis ribosomal small subunit biogenesis ribosomal small subunit biogenesis ribosomal small subunit biogenesis histone binding histone binding identical protein binding identical protein binding protein homodimerization activity ribosomal large subunit binding ribosomal small subunit binding negative regulation of apoptotic process negative regulation of apoptotic process protein kinase B binding regulation of DNA damage response, signal transduction by p53 class mediator regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of protein kinase activity by regulation of protein phosphorylation positive regulation of translation positive regulation of DNA replication positive regulation of protein kinase activity positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of centriole replication negative regulation of mRNA splicing, via spliceosome negative regulation of epithelial cell proliferation protein stabilization protein stabilization positive regulation of DNA metabolic process NF-kappaB binding unfolded protein binding positive regulation of NF-kappaB transcription factor activity regulation of cell cycle regulation of endoribonuclease activity regulation of eIF2 alpha phosphorylation by dsRNA cellular senescence DNA-binding transcription factor binding molecular condensate scaffold activity regulation of mRNA stability involved in cellular response to UV positive regulation of cell cycle G2/M phase transition positive regulation of protein localization to nucleolus positive regulation of protein localization to nucleolus ribonucleoprotein complex ribonucleoprotein complex
1420361_at	Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	1	74375202	NM_013612	18173	249	negative regulation of cytokine production positive regulation of cytokine production T cell proliferation involved in immune response T cell cytokine production positive regulation of dendritic cell antigen processing and presentation positive regulation of T-helper 1 type immune response iron ion transmembrane transporter activity iron ion transmembrane transporter activity iron ion transmembrane transporter activity manganese ion transmembrane transporter activity manganese ion transmembrane transporter activity manganese ion transmembrane transporter activity manganese ion transmembrane transporter activity lysosome lysosomal membrane lysosomal membrane endosome late endosome late endosome plasma membrane plasma membrane monoatomic ion transport iron ion transport iron ion transport manganese ion transport manganese ion transport manganese ion transport manganese ion transport intracellular iron ion homeostasis intracellular iron ion homeostasis phagocytosis inflammatory response vacuolar acidification response to bacterium response to bacterium endosome membrane endosome membrane positive regulation of gene expression cadmium ion transmembrane transporter activity nitrite transport membrane metal ion transport phagocytic vesicle membrane phagocytic vesicle membrane phagocytic vesicle membrane phagocytic vesicle membrane late endosome membrane activation of protein kinase activity response to lipopolysaccharide response to lipopolysaccharide response to lipopolysaccharide type II interferon production interleukin-2 production interleukin-3 production positive regulation of type II interferon production response to type II interferon iron ion transmembrane transport wound healing macrophage activation macrophage activation defense response to bacterium protein homodimerization activity defense response to protozoan MHC class II biosynthetic process respiratory burst positive regulation of transcription by RNA polymerase II metal ion transmembrane transporter activity transition metal ion transmembrane transporter activity antigen processing and presentation of peptide antigen mRNA stabilization positive regulation of phagocytosis defense response to Gram-negative bacterium metal cation:proton antiporter activity metal cation:proton antiporter activity metal cation:proton antiporter activity establishment of localization in cell multicellular organismal-level iron ion homeostasis cadmium ion transmembrane transport tertiary granule membrane cellular detoxification of cadmium ion L-arginine transmembrane transport	04142
1435088_at	Nsd1	nuclear receptor-binding SET-domain protein 1	13	55209781	BM945177	18193	58	negative regulation of transcription by RNA polymerase II chromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding gastrulation with mouth forming second chromatin binding transcription coregulator activity transcription coregulator activity transcription corepressor activity protein binding nucleus nucleus nucleus chromosome chromatin organization regulation of DNA-templated transcription regulation of DNA-templated transcription multicellular organism development methyltransferase activity zinc ion binding transferase activity nuclear estrogen receptor binding methylation regulation of peptidyl-serine phosphorylation histone methyltransferase complex histone methyltransferase activity histone H4K20 methyltransferase activity nuclear retinoic acid receptor binding positive regulation of DNA-templated transcription metal ion binding nuclear retinoid X receptor binding nuclear thyroid hormone receptor binding histone H3K36 methyltransferase activity histone H3K36 methyltransferase activity histone H3K36 methyltransferase activity nuclear androgen receptor binding histone H3K36 dimethyltransferase activity regulation of RNA polymerase II regulatory region sequence-specific DNA binding	00310
1416107_at	Nsg2	neuron specific gene family member 2	11	32001276, 32000699, 32000418, 32000418	NM_008741	18197	25	lysosome endosome endosome early endosome late endosome Golgi apparatus dopamine receptor signaling pathway membrane endosomal transport dendrite cytoplasmic vesicle membrane cytoplasmic vesicle clathrin light chain binding clathrin light chain binding multivesicular body membrane trans-Golgi network membrane cell projection lysosomal lumen clathrin coat assembly clathrin coat assembly Golgi cis cisterna membrane
1451054_at	Orm1	orosomucoid 1	4	63344555	BE628912	18405	62	regulation of immune system process extracellular region extracellular space extracellular space acute-phase response small molecule binding
1420967_at	Slc25a15	solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15	8	-22375549, -22375549	AW541300	18408	20	L-ornithine transmembrane transporter activity L-ornithine transmembrane transporter activity mitochondrion mitochondrion mitochondrion mitochondrial inner membrane L-lysine transmembrane transporter activity antiporter activity membrane L-arginine transmembrane transporter activity L-lysine transmembrane transport L-arginine transmembrane transport mitochondrial L-ornithine transmembrane transport
1421456_at	P2ry1	purinergic receptor P2Y, G-protein coupled 1	3	61002784	NM_008772	18441	124	nucleotide binding G protein-coupled ADP receptor activity G protein-coupled ADP receptor activity positive regulation of protein phosphorylation G protein-coupled adenosine receptor signaling pathway G protein-coupled receptor activity ATP binding ATP binding plasma membrane plasma membrane plasma membrane cilium monoatomic ion transport monoatomic ion transport signal transduction G protein-coupled receptor signaling pathway adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration glial cell migration regulation of cell shape response to mechanical stimulus negative regulation of norepinephrine secretion postsynaptic density membrane basolateral plasma membrane apical plasma membrane signal transduction involved in regulation of gene expression platelet activation dendrite A1 adenosine receptor binding A1 adenosine receptor binding positive regulation of inositol trisphosphate biosynthetic process G protein-coupled purinergic nucleotide receptor signaling pathway eating behavior positive regulation of monoatomic ion transport positive regulation of monoatomic ion transport ADP binding cell body G protein-coupled purinergic nucleotide receptor activity G protein-coupled ATP receptor activity G protein-coupled ATP receptor activity postsynaptic membrane positive regulation of transcription by RNA polymerase II positive regulation of hormone secretion protein heterodimerization activity presynaptic active zone membrane establishment of localization in cell establishment of localization in cell positive regulation of penile erection positive regulation of ERK1 and ERK2 cascade cellular response to organic cyclic compound cellular response to purine-containing compound protein localization to plasma membrane relaxation of muscle scaffold protein binding blood vessel diameter maintenance glutamatergic synapse regulation of presynaptic cytosolic calcium ion concentration regulation of synaptic vesicle exocytosis	04080
1416410_at	Pafah1b3	platelet-activating factor acetylhydrolase, isoform 1b, subunit 3	7	-25295048, -25295048	NM_008776	18476	37	1-alkyl-2-acetylglycerophosphocholine esterase activity protein binding cytoplasm cytoplasm lipid metabolic process spermatogenesis spermatogenesis 1-alkyl-2-acetylglycerophosphocholine esterase complex lipid catabolic process hydrolase activity identical protein binding protein homodimerization activity protein-containing complex binding protein heterodimerization activity platelet-activating factor acetyltransferase activity platelet-activating factor acetyltransferase activity	00565 01100
1454638_a_at	Pah	phenylalanine hydroxylase	10	87521794	AW106920	18478	125	catalytic activity monooxygenase activity phenylalanine 4-monooxygenase activity phenylalanine 4-monooxygenase activity phenylalanine 4-monooxygenase activity iron ion binding L-phenylalanine metabolic process L-phenylalanine catabolic process tyrosine biosynthetic process tyrosine biosynthetic process metabolic process aromatic amino acid metabolic process oxidoreductase activity amino acid binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen tyrosine biosynthetic process, by oxidation of phenylalanine tyrosine biosynthetic process, by oxidation of phenylalanine identical protein binding metal ion binding	00360 00400 01100
1420979_at	Pak1	p21 (RAC1) activated kinase 1	7	97842938, 97788540	BF456404	18479	224	nucleotide binding response to hypoxia ruffle positive regulation of protein phosphorylation catalytic activity protein kinase activity protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding collagen binding ATP binding nucleus nucleoplasm chromosome cytoplasm cytoplasm cytoplasm cytosol cytoskeleton actin filament plasma membrane cell-cell junction focal adhesion chromatin remodeling protein phosphorylation protein phosphorylation exocytosis apoptotic process DNA damage response neuromuscular junction development metabolic process positive regulation of cell population proliferation response to organic substance regulation of gene expression positive regulation of fibroblast migration postsynaptic density postsynaptic density intercalated disc membrane kinase activity phosphorylation dendrite development cell migration transferase activity transmission of nerve impulse protein kinase binding amygdala development establishment of cell polarity Z disc lamellipodium actin cytoskeleton organization positive regulation of cell migration axon axon dendrite dendrite growth cone positive regulation of microtubule polymerization small GTPase binding nuclear membrane cellular response to insulin stimulus regulation of actin cytoskeleton organization regulation of actin cytoskeleton organization protein-containing complex positive regulation of peptidyl-serine phosphorylation positive regulation of intracellular estrogen receptor signaling pathway intracellular signal transduction wound healing identical protein binding cell projection gamma-tubulin binding receptor clustering regulation of MAPK cascade regulation of MAPK cascade positive regulation of JUN kinase activity positive regulation of axon extension positive regulation of insulin receptor signaling pathway protein autophosphorylation hepatocyte growth factor receptor signaling pathway branching morphogenesis of an epithelial tube neuron projection morphogenesis regulation of axonogenesis localization positive regulation of stress fiber assembly negative regulation of cell proliferation involved in contact inhibition dendritic spine development negative regulation of cell growth involved in cardiac muscle cell development gamma-aminobutyric acid secretion, neurotransmission glutamate secretion, neurotransmission anchoring junction cellular response to organic cyclic compound positive regulation of microtubule nucleation positive regulation of protein targeting to membrane observational learning glutamatergic synapse glutamatergic synapse glutamatergic synapse GABA-ergic synapse GABA-ergic synapse GABA-ergic synapse GABA-ergic synapse regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission regulation of long-term synaptic potentiation protein localization to cytoplasmic stress granule positive regulation of vascular associated smooth muscle cell proliferation positive regulation of vascular associated smooth muscle cell migration	04010 04012 04062 04360 04510 04650 04660 04666 04810 05211
1458978_at	Pax5	paired box 5	4	-44524750	BG144033	18507	229	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm transcription regulator complex regulation of DNA-templated transcription regulation of transcription by RNA polymerase II multicellular organism development spermatogenesis nervous system development animal organ morphogenesis lateral ventricle development cerebral cortex development cell differentiation adult behavior skeletal muscle cell differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II embryonic cranial skeleton morphogenesis anatomical structure development dopaminergic neuron differentiation
1418840_at	Pdcd4	programmed cell death 4	19	53903350, 53892230	NM_011050	18569	101	RNA binding protein binding nucleus nucleus cytoplasm cytosol cytosol apoptotic process BMP signaling pathway positive regulation of smooth muscle cell apoptotic process negative regulation of apoptotic process negative regulation of DNA-templated transcription positive regulation of inflammatory response regulation of protein metabolic process epithelial to mesenchymal transition involved in cardiac fibroblast development cellular response to lipopolysaccharide negative regulation of cytokine production involved in inflammatory response positive regulation of non-canonical NF-kappaB signal transduction negative regulation of vascular associated smooth muscle cell proliferation negative regulation of myofibroblast differentiation negative regulation of vascular associated smooth muscle cell differentiation positive regulation of vascular associated smooth muscle cell apoptotic process positive regulation of endothelial cell apoptotic process
1422474_at	Pde4b	phosphodiesterase 4B, cAMP specific	4	102589842, 102254938, 102254741, 102570059, 102587557, 102421554	BM246564	18578	79	gamma-tubulin complex neutrophil homeostasis 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity calcium channel regulator activity protein binding nucleus centrosome cytosol cytosol voltage-gated calcium channel complex synaptic vesicle postsynaptic density membrane cAMP-mediated signaling Z disc cAMP binding neutrophil chemotaxis positive regulation of type II interferon production positive regulation of interleukin-2 production gamma-tubulin binding dendritic spine transmembrane transporter binding transmembrane transporter binding 3',5'-cyclic-GMP phosphodiesterase activity perinuclear region of cytoplasm perinuclear region of cytoplasm T cell receptor signaling pathway leukocyte migration excitatory synapse cellular response to lipopolysaccharide cellular response to xenobiotic stimulus cellular response to epinephrine stimulus negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway cell periphery regulation of cardiac muscle cell contraction negative regulation of relaxation of cardiac muscle regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	00230
1458218_s_at	Pde7a	phosphodiesterase 7A	3	-19223108, -19223108	AU015378	18583	30	cyclic-nucleotide phosphodiesterase activity 3',5'-cyclic-nucleotide phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity 3',5'-cyclic-AMP phosphodiesterase activity nucleus cytoplasm cytosol signal transduction phosphoric diester hydrolase activity hydrolase activity cAMP-mediated signaling cAMP-mediated signaling cAMP-mediated signaling metal ion binding 3',5'-cyclic-GMP phosphodiesterase activity perinuclear region of cytoplasm	00230
1422760_at	Padi4	peptidyl arginine deiminase, type IV	4	-140745507	NM_011061	18602	120	immune system process protein-arginine deiminase activity protein-arginine deiminase activity protein-arginine deiminase activity calcium ion binding nucleus nucleus cytoplasm cytoplasm chromatin organization nucleosome assembly chromatin remodeling chromatin remodeling hydrolase activity stem cell population maintenance protein-containing complex identical protein binding post-translational protein modification innate immune response metal ion binding histone arginine deiminase activity histone arginine deiminase activity histone H3R2 arginine deiminase activity histone H3R8 arginine deiminase activity histone H3R17 arginine deiminase activity histone H3R26 arginine deiminase activity
1419276_at	Enpp1	ectonucleotide pyrophosphatase/phosphodiesterase 1	10	-24637913	AF339910	18605	147	cell morphogenesis cell morphogenesis ossification vasculogenesis osteoblast differentiation osteoblast differentiation kidney development B-1 B cell homeostasis endochondral ossification morphogenesis of an epithelium response to dietary excess leukocyte activation involved in inflammatory response plasma cell differentiation immunoglobulin production involved in immunoglobulin-mediated immune response inflammatory response to antigenic stimulus nucleic acid binding exonuclease activity phosphodiesterase I activity phosphodiesterase I activity phosphodiesterase I activity phosphodiesterase I activity dinucleotide phosphatase activity dinucleotide phosphatase activity dinucleotide phosphatase activity scavenger receptor activity insulin receptor binding calcium ion binding ATP binding extracellular region extracellular region extracellular space extracellular space extracellular space plasma membrane plasma membrane generation of precursor metabolites and energy glycolytic process fatty acid metabolic process phosphate-containing compound metabolic process nitrogen compound metabolic process immune response mitochondrion organization smoothened signaling pathway heart development sensory perception of sound adult walking behavior phosphoric diester hydrolase activity zinc ion binding cell population proliferation cell population proliferation determination of adult lifespan adult locomotory behavior fibroblast growth factor receptor signaling pathway nucleoside triphosphate catabolic process nucleoside triphosphate catabolic process response to wounding cell surface cell surface cell surface response to inorganic substance gene expression gene expression gene expression gene expression coenzyme A diphosphatase activity magnesium ion homeostasis microglia differentiation coenzyme A catabolic process coenzyme A catabolic process membrane Wnt signaling pathway pyrophosphatase activity hydrolase activity phosphatase activity phosphatase activity phosphatase activity organic phosphonate metabolic process cellular homeostasis cellular homeostasis spinal cord development central nervous system myelination T cell differentiation macrophage differentiation polysaccharide binding negative regulation of ossification bone mineralization bone mineralization bone mineralization bone mineralization negative regulation of cell growth osteoclast differentiation melanocyte differentiation regulation of bone mineralization negative regulation of bone mineralization inorganic diphosphate transport inorganic diphosphate transport inorganic diphosphate transport inorganic diphosphate transport inorganic diphosphate transport intracellular phosphate ion homeostasis sequestering of triglyceride axon regeneration biomineral tissue development negative regulation of protein autophosphorylation response to magnesium ion response to magnesium ion type II interferon production response to insulin cellular response to insulin stimulus response to ATP tooth mineralization response to vitamin B6 post-embryonic forelimb morphogenesis multicellular organism growth bone mineralization involved in bone maturation aorta development ligamentous ossification response to platelet-derived growth factor collagen-activated signaling pathway hormone metabolic process middle ear morphogenesis odontogenesis glucose homeostasis mRNA transcription by RNA polymerase II identical protein binding protein homodimerization activity protein homodimerization activity defense response to protozoan cell projection neuronal cell body skin development cell body fat cell differentiation bone resorption negative regulation of fat cell differentiation negative regulation of fat cell differentiation negative regulation of fat cell differentiation negative regulation of glycogen biosynthetic process ATP metabolic process ATP metabolic process ATP metabolic process glucose import negative regulation of glucose import negative regulation of insulin receptor signaling pathway muscle cell cellular homeostasis bone remodeling metal ion binding nucleoside triphosphate diphosphatase activity nucleoside triphosphate diphosphatase activity 3'-phosphoadenosine 5'-phosphosulfate metabolic process sensory perception of temperature stimulus sensory perception of mechanical stimulus cartilage development neuron apoptotic process establishment of localization in cell phosphate ion homeostasis phosphate ion homeostasis phosphate ion homeostasis phosphate ion homeostasis calcium ion homeostasis calcium ion homeostasis long-term synaptic potentiation bone trabecula formation bone development endochondral bone morphogenesis adipose tissue development fat pad development artery development articular cartilage development protein poly-ADP-ribosylation mucus secretion vitamin D3 metabolic process diphosphate metabolic process diphosphate metabolic process cementum mineralization cementum mineralization cementum mineralization nucleic acid metabolic process hematopoietic stem cell migration to bone marrow oligodendrocyte apoptotic process apical dendrite basal dendrite bone growth cyclic-GMP-AMP hydrolase activity cyclic-GMP-AMP hydrolase activity cyclic-GMP-AMP hydrolase activity response to Gram-positive bacterium inhibition of non-skeletal tissue mineralization inhibition of non-skeletal tissue mineralization inhibition of non-skeletal tissue mineralization inhibition of non-skeletal tissue mineralization apoptotic process involved in development microglial cell migration response to sodium phosphate response to sodium phosphate cellular response to sodium phosphate vascular associated smooth muscle cell migration negative regulation of hh target transcription factor activity vascular associated smooth muscle cell proliferation	00230 00500 00740 00760 00770 01100
1452279_at	Cfp	complement factor properdin	X	-20925453	BB800282	18636	53	immune system process extracellular region extracellular space complement activation complement activation, alternative pathway secretory granule innate immune response positive regulation of immune response cytoplasmic side of Golgi membrane cytoplasmic side of Golgi membrane positive regulation of opsonization
1418209_a_at	Pfn2	profilin 2	3	-57841894	NM_019410	18645	64	actin binding actin binding actin monomer binding protein binding phosphatidylinositol-4,5-bisphosphate binding cytoplasm cytoplasm cytosol cytoskeleton negative regulation of epithelial cell migration negative regulation of epithelial cell migration ATP hydrolysis activity actin cytoskeleton organization regulation of actin filament polymerization regulation of actin filament polymerization negative regulation of actin filament polymerization positive regulation of actin filament polymerization positive regulation of actin filament polymerization positive regulation of actin filament bundle assembly positive regulation of actin filament bundle assembly positive regulation of ATP-dependent activity positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation modulation of chemical synaptic transmission modulation of chemical synaptic transmission protein stabilization positive regulation of stress fiber assembly positive regulation of stress fiber assembly Schaffer collateral - CA1 synapse presynapse postsynapse modification of postsynaptic actin cytoskeleton modification of postsynaptic actin cytoskeleton glutamatergic synapse glutamatergic synapse presynaptic modulation of chemical synaptic transmission presynaptic modulation of chemical synaptic transmission negative regulation of ruffle assembly negative regulation of ruffle assembly regulation of synaptic vesicle exocytosis	04810
1426554_a_at	Pgam1	phosphoglycerate mutase 1	19	41911870	BI407347	18648	60	catalytic activity bisphosphoglycerate mutase activity phosphoglycerate mutase activity phosphoglycerate mutase activity cytoplasm cytosol cytosol gluconeogenesis glycolytic process hydrolase activity isomerase activity intramolecular phosphotransferase activity protein kinase binding myelin sheath glyceraldehyde-3-phosphate biosynthetic process 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity sperm principal piece	00010 01100
1438640_x_at	Pgk1	phosphoglycerate kinase 1	X	106187099	AV305101	18655	202	nucleotide binding phosphoglycerate kinase activity phosphoglycerate kinase activity phosphoglycerate kinase activity protein binding ATP binding ATP binding extracellular space cytoplasm cytosol cytosol gluconeogenesis gluconeogenesis glycolytic process glycolytic process glycolytic process kinase activity phosphorylation negative regulation of angiogenesis transferase activity plasminogen activation ADP binding ADP binding membrane raft glyceraldehyde-3-phosphate biosynthetic process protein-disulfide reductase (NAD(P)) activity canonical glycolysis cellular response to hypoxia	00010 01100
1424302_at	Pirb	paired Ig-like receptor B	7	-3712504, -3712506	U96693	18733	87	amyloid-beta binding amyloid-beta binding B cell homeostasis adaptive immune response immune system process protein binding extracellular space cytoplasm plasma membrane plasma membrane learning or memory protein phosphatase 1 binding external side of plasma membrane cell surface membrane cytokine-mediated signaling pathway cytokine-mediated signaling pathway B cell mediated immunity MHC class Ib protein complex binding MHC class Ib protein binding HLA-A specific inhibitory MHC class I receptor activity HLA-B specific inhibitory MHC class I receptor activity MHC class I receptor activity MHC class Ib receptor activity inhibitory MHC class I receptor activity inhibitory MHC class I receptor activity positive regulation of protein dephosphorylation SH2 domain binding MHC class I protein binding protein homodimerization activity protein homodimerization activity myeloid dendritic cell differentiation protein-containing complex binding protein-containing complex binding negative regulation of osteoclast differentiation cell adhesion molecule binding negative regulation of protein metabolic process regulation of long-term synaptic potentiation positive regulation of long-term synaptic depression	04380 04662
1420611_at	Prkacb	protein kinase, cAMP dependent, catalytic, beta	3	-146729578, -146729578, -146729578, -146729578	AV024339	18749	72	nucleotide binding magnesium ion binding magnesium ion binding neural tube closure protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity AMP-activated protein kinase activity cAMP-dependent protein kinase activity cAMP-dependent protein kinase activity cAMP-dependent protein kinase activity ATP binding ATP binding nucleus nucleus cytoplasm centrosome cytosol cytosol plasma membrane cAMP-dependent protein kinase complex cAMP-dependent protein kinase complex cAMP-dependent protein kinase complex protein phosphorylation protein phosphorylation adenylate cyclase-modulating G protein-coupled receptor signaling pathway protein kinase A signaling membrane kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation ubiquitin protein ligase binding negative regulation of smoothened signaling pathway perinuclear region of cytoplasm negative regulation of meiotic cell cycle regulation of protein processing ciliary base negative regulation of TORC1 signaling	04010 04020 04062 04114 04210 04270 04310 04340 04540 04720 04740 04742 04910 04912 04914 04916 04962 04970 04971 04976 05020 05146 05414
1460419_a_at	Prkcb	protein kinase C, beta	7	122289124	X59274	18751	236	nucleotide binding adaptive immune response immune system process chromatin binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity diacylglycerol-dependent serine/threonine kinase activity diacylglycerol-dependent serine/threonine kinase activity protein kinase C binding calcium channel regulator activity protein binding ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm centrosome cytosol plasma membrane plasma membrane chromatin organization regulation of transcription by RNA polymerase II protein phosphorylation calcium ion transport intracellular calcium ion homeostasis apoptotic process phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway spectrin zinc ion binding response to xenobiotic stimulus regulation of glucose transmembrane transport negative regulation of glucose transmembrane transport regulation of dopamine secretion kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation nuclear receptor coactivator activity positive regulation of vascular endothelial growth factor receptor signaling pathway brush border membrane positive regulation of insulin secretion histone H3T6 kinase activity intracellular signal transduction regulation of growth B cell activation histone binding positive regulation of canonical NF-kappaB signal transduction post-translational protein modification calyx of Held calyx of Held positive regulation of angiogenesis negative regulation of insulin receptor signaling pathway metal ion binding nuclear androgen receptor binding B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway cellular response to carbohydrate stimulus presynapse presynaptic modulation of chemical synaptic transmission presynaptic modulation of chemical synaptic transmission presynaptic cytosol regulation of synaptic vesicle exocytosis regulation of synaptic vesicle exocytosis	04010 04012 04020 04062 04070 04270 04310 04370 04510 04530 04540 04650 04662 04664 04666 04670 04720 04730 04912 04916 04960 04970 04971 04972 04973 05140 05143 05146 05200 05214 05223
1450172_at	Pknox1	Pbx/knotted 1 homeobox	17	31564772	AA409923	18771	99	RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific angiogenesis angiogenesis DNA binding chromatin binding protein binding nucleus nucleoplasm transcription regulator complex cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II hemopoiesis T cell differentiation erythrocyte differentiation camera-type eye development sequence-specific DNA binding positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding
1452521_a_at	Plaur	plasminogen activator, urokinase receptor	7	24462482	X62701	18793	202	positive regulation of protein phosphorylation signaling receptor binding protein binding extracellular region plasma membrane plasma membrane plasma membrane external side of plasma membrane cell surface regulation of plasminogen activation membrane enzyme binding protein domain specific binding regulation of cell adhesion positive regulation of homotypic cell-cell adhesion urokinase plasminogen activator signaling pathway negative regulation of apoptotic process positive regulation of DNA binding positive regulation of epidermal growth factor receptor signaling pathway mesenchymal cell differentiation regulation of fibrinolysis epithelial cell differentiation involved in prostate gland development positive regulation of release of cytochrome c from mitochondria side of membrane protein complex involved in cell-matrix adhesion serine-type endopeptidase complex serine-type endopeptidase complex negative regulation of intrinsic apoptotic signaling pathway negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	04610
1435043_at	Plcb1	phospholipase C, beta 1	2	134786163	BB794831	18795	121	G2/M transition of mitotic cell cycle G2/M transition of mitotic cell cycle chromatin oocyte maturation phosphatidylinositol phospholipase C activity phosphatidylinositol phospholipase C activity phosphatidylinositol phospholipase C activity GTPase activator activity calcium ion binding protein binding calmodulin binding calmodulin binding lamin binding phosphatidylinositol-4,5-bisphosphate binding nucleus nucleus cytoplasm cytoplasm cytoplasm plasma membrane plasma membrane mRNA processing lipid metabolic process cell adhesion signal transduction G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway G protein-coupled acetylcholine receptor signaling pathway glutamate receptor signaling pathway brain development memory memory phosphoric diester hydrolase activity regulation of G protein-coupled receptor signaling pathway insulin receptor signaling pathway membrane lipid catabolic process nuclear speck nuclear speck nuclear speck hydrolase activity enzyme binding cerebral cortex development erythrocyte differentiation macrophage differentiation phosphatidylinositol catabolic process positive regulation of insulin secretion positive regulation of insulin secretion positive regulation of sodium:proton antiporter activity positive regulation of interleukin-12 production inositol trisphosphate metabolic process protein-containing complex response to monosaccharide intracellular signal transduction interleukin-12-mediated signaling pathway interleukin-15-mediated signaling pathway positive regulation of embryonic development identical protein binding myelin sheath response to peptide hormone fat cell differentiation positive regulation of myoblast differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of JNK cascade phosphatidylinositol metabolic process phosphatidylinositol metabolic process insulin-like growth factor receptor signaling pathway phosphatidylinositol-mediated signaling positive regulation of developmental growth release of sequestered calcium ion into cytosol activation of meiosis involved in egg activation interleukin-1-mediated signaling pathway regulation of fertilization glutamatergic synapse glutamatergic synapse glutamatergic synapse GABA-ergic synapse GABA-ergic synapse ion channel modulating, G protein-coupled receptor signaling pathway postsynaptic modulation of chemical synaptic transmission postsynaptic modulation of chemical synaptic transmission postsynaptic modulation of chemical synaptic transmission regulation of retrograde trans-synaptic signaling by endocanabinoid regulation of retrograde trans-synaptic signaling by endocanabinoid postsynaptic cytosol postsynaptic cytosol positive regulation of G1/S transition of mitotic cell cycle cellular response to fluoride regulation of establishment of endothelial barrier cellular response to vasopressin cellular response to ionomycin cellular response to glyceraldehyde ligand-gated ion channel signaling pathway positive regulation of acrosome reaction negative regulation of monocyte extravasation positive regulation of CD24 production	00562 01100 04020 04062 04070 04270 04310 04540 04720 04730 04912 04916 04970 04971 04972 05010 05016 05142 05143 05146
1435149_at	Plcg1	phospholipase C, gamma 1	2	160731309	BM121087	18803	204	in utero embryonic development ruffle phosphatidylinositol phospholipase C activity phosphatidylinositol phospholipase C activity phosphatidylinositol phospholipase C activity phospholipase C activity phospholipase C activity guanyl-nucleotide exchange factor activity insulin receptor binding neurotrophin TRKA receptor binding calcium ion binding protein binding cytoplasm cytosol cytosol plasma membrane plasma membrane cell-cell junction lipid metabolic process calcium ion transport signal transduction epidermal growth factor receptor signaling pathway phosphoric diester hydrolase activity COP9 signalosome phospholipid catabolic process response to organonitrogen compound positive regulation of epithelial cell migration positive regulation of epithelial cell migration lipid catabolic process cell migration hydrolase activity calcium-mediated signaling protein kinase binding lamellipodium clathrin-coated vesicle receptor tyrosine kinase binding phosphatidylinositol catabolic process ruffle membrane ruffle membrane inositol trisphosphate metabolic process inositol trisphosphate biosynthetic process glutamate receptor binding intracellular signal transduction cell projection positive regulation of blood vessel endothelial cell migration positive regulation of angiogenesis phosphatidylinositol metabolic process phosphatidylinositol metabolic process metal ion binding phosphatidylinositol-mediated signaling calcium-dependent phospholipase C activity modulation of chemical synaptic transmission modulation of chemical synaptic transmission T cell receptor signaling pathway release of sequestered calcium ion into cytosol phosphoprotein binding positive regulation of release of sequestered calcium ion into cytosol cellular response to epidermal growth factor stimulus Schaffer collateral - CA1 synapse Schaffer collateral - CA1 synapse glutamatergic synapse glutamatergic synapse response to curcumin positive regulation of vascular endothelial cell proliferation positive regulation of endothelial cell apoptotic process	00562 01100 04012 04020 04070 04370 04650 04660 04664 04666 04670 04722 05200 05214 05223
1437113_s_at	Pld1	phospholipase D1	3	27984170, 27938679	BM228590	18805	126	catalytic activity phospholipase D activity phospholipase D activity phospholipase D activity protein binding cytoplasm endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus lipid metabolic process phosphatidic acid biosynthetic process phospholipid biosynthetic process phospholipid catabolic process phospholipid catabolic process membrane lipid catabolic process apical plasma membrane hydrolase activity lamellipodium endocytic vesicle positive regulation of cell migration cellular response to nutrient vesicle Golgi cisterna regulation of microvillus assembly regulation of microvillus assembly phosphatidylinositol binding intracellular membrane-bounded organelle response to peptide hormone synapse positive regulation of translation defense response to Gram-positive bacterium regulation of vesicle-mediated transport N-acylphosphatidylethanolamine-specific phospholipase D activity plasma membrane region regulation of synaptic vesicle cycle cholinergic synapse	00564 00565 01100 04144 04666 04912 05212
1416289_at	Plod1	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1	4	-147909752	NM_011122	18822	43	iron ion binding protein binding endoplasmic reticulum endoplasmic reticulum ferrous iron binding procollagen-lysine 5-dioxygenase activity procollagen-lysine 5-dioxygenase activity epidermis development membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen peptidyl-lysine hydroxylation peptidyl-lysine hydroxylation L-ascorbic acid binding peptide binding metal ion binding dioxygenase activity collagen-containing extracellular matrix catalytic complex	00310
1456103_at	Pml	promyelocytic leukemia	9	-58217179	BB667149	18854	209	chromosome, telomeric region heterochromatin response to hypoxia response to hypoxia positive regulation of defense response to virus by host immune system process DNA binding transcription coactivator activity transcription coactivator activity protein binding nucleus nucleus nucleoplasm nucleoplasm nucleolus cytoplasm endosome endoplasmic reticulum cytosol regulation of DNA-templated transcription protein targeting protein import into nucleus apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest transforming growth factor beta receptor signaling pathway zinc ion binding negative regulation of cell population proliferation negative regulation of cell population proliferation intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to DNA damage intrinsic apoptotic signaling pathway in response to oxidative stress response to UV response to gamma radiation regulation of calcium ion transport into cytosol fibroblast migration membrane nuclear matrix nuclear matrix negative regulation of angiogenesis negative regulation of angiogenesis PML body PML body PML body PML body SUMO transferase activity SUMO transferase activity myeloid cell differentiation regulation of cell adhesion negative regulation of cell growth PML body organization PML body organization protein-containing complex localization ubiquitin protein ligase binding nuclear membrane SUMO binding positive regulation of telomere maintenance negative regulation of telomere maintenance via telomerase endoplasmic reticulum calcium ion homeostasis negative regulation of interleukin-1 beta production negative regulation of interleukin-1 production circadian regulation of gene expression negative regulation of translation in response to oxidative stress response to cytokine regulation of circadian rhythm intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator identical protein binding protein homodimerization activity entrainment of circadian clock by photoperiod proteasome-mediated ubiquitin-dependent protein catabolic process suppression of viral release by host suppression of viral release by host suppression of viral release by host innate immune response innate immune response innate immune response cell fate commitment negative regulation of DNA-templated transcription negative regulation of mitotic cell cycle SMAD binding metal ion binding protein heterodimerization activity positive regulation of fibroblast proliferation retinoic acid receptor signaling pathway rhythmic process protein stabilization cobalt ion binding maintenance of protein location in nucleus defense response to virus regulation of cell cycle negative regulation of telomerase activity positive regulation of apoptotic process involved in mammary gland involution molecular adaptor activity SMAD protein signal transduction branching involved in mammary gland duct morphogenesis ubiquitin-like protein ligase activity protein-containing complex assembly intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress cellular response to interleukin-4 intrinsic apoptotic signaling pathway by p53 class mediator cellular senescence oncogene-induced cell senescence extrinsic apoptotic signaling pathway sumo-dependent protein binding positive regulation of signal transduction by p53 class mediator positive regulation of protein localization to chromosome, telomeric region cellular response to leukemia inhibitory factor negative regulation of ubiquitin-dependent protein catabolic process positive regulation of peptidyl-lysine acetylation regulation of double-strand break repair positive regulation of apoptotic signaling pathway positive regulation of apoptotic signaling pathway positive regulation of extrinsic apoptotic signaling pathway	04120 04144 05200 05221
1416530_a_at	Pnp	purine-nucleoside phosphorylase	14	50944302	BC003788	18950	89	allantoin metabolic process allantoin metabolic process allantoin metabolic process nucleoside binding positive regulation of T cell mediated cytotoxicity purine nucleobase binding catalytic activity purine-nucleoside phosphorylase activity purine-nucleoside phosphorylase activity purine-nucleoside phosphorylase activity purine-nucleoside phosphorylase activity extracellular region cytoplasm cytoplasm cytosol cytosol nucleobase-containing compound metabolic process inosine catabolic process inosine catabolic process inosine catabolic process deoxyinosine catabolic process deoxyinosine catabolic process adenosine catabolic process adenosine catabolic process deoxyadenosine catabolic process deoxyadenosine catabolic process deoxyguanosine catabolic process purine ribonucleoside salvage GTP biosynthetic process AMP catabolic process AMP catabolic process GMP catabolic process to guanine IMP catabolic process IMP catabolic process DNA repair nicotinamide riboside catabolic process immune response intrinsic apoptotic signaling pathway in response to DNA damage apoptotic mitochondrial changes nucleoside metabolic process nucleotide biosynthetic process response to xenobiotic stimulus response to gamma radiation transferase activity glycosyltransferase activity pentosyltransferase activity B cell differentiation GMP salvage IMP salvage positive regulation of interleukin-2 production urate biosynthetic process urate biosynthetic process T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation purine nucleoside metabolic process purine nucleoside metabolic process purine nucleoside metabolic process phosphate ion binding identical protein binding purine-containing compound salvage amide catabolic process amide catabolic process amide catabolic process AMP salvage positive regulation of B cell differentiation positive regulation of DNA repair GMP catabolic process dGMP catabolic process dGMP catabolic process dAMP catabolic process dAMP catabolic process dGTP metabolic process guanosine catabolic process alpha-beta T cell differentiation positive regulation of alpha-beta T cell differentiation positive regulation of alpha-beta T cell differentiation guanosine phosphorylase activity T cell apoptotic process negative regulation of T cell apoptotic process	00230 00240 00760 01100
1423272_at	Polg	polymerase (DNA directed), gamma	7	-79446230, -79446230	BM934958	18975	128	protease binding DNA binding chromatin binding DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity exonuclease activity protein binding mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial matrix gamma DNA polymerase complex DNA replication DNA-templated DNA replication mitochondrial DNA replication mitochondrial DNA replication mitochondrial DNA replication single-stranded DNA 3'-5' DNA exonuclease activity determination of adult lifespan 3'-5' exonuclease activity 3'-5' exonuclease activity transferase activity nucleotidyltransferase activity protein-containing complex mitochondrial nucleoid terminal bouton intracellular membrane-bounded organelle DNA replication proofreading 5'-deoxyribose-5-phosphate lyase activity	01100
1418190_at	Pon1	paraoxonase 1	6	-5168089	NM_011134	18979	101	aryldialkylphosphatase activity aryldialkylphosphatase activity arylesterase activity arylesterase activity arylesterase activity calcium ion binding phospholipid binding extracellular region extracellular space extracellular space blood circulation high-density lipoprotein particle binding cholesterol metabolic process cholesterol metabolic process response to toxic substance response to toxic substance positive regulation of cholesterol efflux hydrolase activity aromatic compound catabolic process positive regulation of transporter activity high-density lipoprotein particle spherical high-density lipoprotein particle protein homodimerization activity carboxylic acid catabolic process organophosphate catabolic process phosphatidylcholine metabolic process metal ion binding positive regulation of binding acyl-L-homoserine-lactone lactonohydrolase activity response to fluoride	01100
1416957_at	Pou2af1	POU domain, class 2, associating factor 1	9	51213689	NM_011136	18985	83	germinal center B cell differentiation DNA binding transcription coactivator activity transcription coactivator activity transcription coactivator activity protein binding nucleus positive regulation of interleukin-6 production positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II POU domain binding RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex cellular response to virus
1449937_at	Endou	endonuclease, polyU-specific	15	-97711018, -97711018	AI528824	19011	17	RNA binding nuclease activity endonuclease activity RNA endonuclease activity RNA endonuclease activity scavenger receptor activity extracellular region cytoplasm proteolysis immune response post-transcriptional gene silencing hydrolase activity lyase activity polysaccharide binding metal ion binding negative regulation of lipid catabolic process
1448380_at	Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	11	-118392746	NM_011150	19039	41	scavenger receptor activity scavenger receptor activity protein binding extracellular region extracellular space extracellular space extracellular space cell adhesion membrane
1420743_a_at	Ppp3cc	protein phosphatase 3, catalytic subunit, gamma isoform	14	-70222978, -70217864	NM_008915	19057	40	phosphoprotein phosphatase activity protein serine/threonine phosphatase activity calcium-dependent protein serine/threonine phosphatase activity calcium-dependent protein serine/threonine phosphatase activity calcium-dependent protein serine/threonine phosphatase activity protein binding calmodulin binding calmodulin binding cytoplasm cytoplasm mitochondrion cytosol calcineurin complex calcineurin complex calcineurin complex calcineurin complex protein dephosphorylation penetration of zona pellucida protein serine/threonine phosphatase complex hydrolase activity myosin phosphatase activity calcineurin-NFAT signaling cascade calmodulin-dependent protein phosphatase activity calmodulin-dependent protein phosphatase activity sperm flagellum metal ion binding positive regulation of calcineurin-NFAT signaling cascade sperm midpiece sperm mitochondrial sheath calcineurin-mediated signaling calcineurin-mediated signaling presynapse glutamatergic synapse glutamatergic synapse presynaptic cytosol regulation of synaptic vesicle endocytosis positive regulation of synaptic vesicle endocytosis positive regulation of calcium ion import across plasma membrane negative regulation of calcium ion import across plasma membrane	04010 04020 04114 04210 04310 04360 04370 04380 04650 04660 04662 04720 05010 05014
1421926_at	Mapk11	mitogen-activated protein kinase 11	15	-89142483	AV329330	19094	82	MAPK cascade nucleotide binding osteoblast differentiation protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity MAP kinase activity MAP kinase activity MAP kinase activity protein binding ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol cytosol protein phosphorylation positive regulation of gene expression kinase activity phosphorylation transferase activity stress-activated protein kinase signaling cascade positive regulation of interleukin-12 production intracellular signal transduction p38MAPK cascade stress-activated MAPK cascade stress-activated MAPK cascade cardiac muscle cell proliferation regulation of cardiac muscle cell proliferation negative regulation of cardiac muscle cell proliferation bone development cellular response to interleukin-1 cellular response to UV-B cellular response to virus	04010 04370 04380 04620 04621 04622 04660 04664 04670 04722 04912 04914 05014 05140 05142 05145 05160
1440866_at	Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	17	-78852549	AV328340	19106	234	nucleotide binding positive regulation of cytokine production immune system process RNA binding double-stranded RNA binding double-stranded RNA binding protein kinase activity protein kinase activity protein kinase activity protein serine/threonine kinase activity eukaryotic translation initiation factor 2alpha kinase activity eukaryotic translation initiation factor 2alpha kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding nucleus nucleus cytoplasm cytoplasm cytosol translation protein phosphorylation protein phosphorylation response to virus response to toxic substance kinase activity phosphorylation transferase activity negative regulation of translation endoplasmic reticulum unfolded protein response response to lipopolysaccharide positive regulation of chemokine production positive regulation of stress-activated MAPK cascade response to vitamin E negative regulation of osteoblast proliferation cellular response to amino acid starvation response to interferon-alpha eiF2alpha phosphorylation in response to endoplasmic reticulum stress identical protein binding positive regulation of apoptotic process negative regulation of apoptotic process positive regulation of MAPK cascade negative regulation of viral genome replication negative regulation of viral genome replication innate immune response protein autophosphorylation protein autophosphorylation perinuclear region of cytoplasm positive regulation of NF-kappaB transcription factor activity defense response to virus antiviral innate immune response regulation of NLRP3 inflammasome complex assembly positive regulation of non-canonical NF-kappaB signal transduction regulation of hematopoietic progenitor cell differentiation regulation of hematopoietic stem cell proliferation regulation of hematopoietic stem cell differentiation	04141 05160
1455696_a_at	Prpf4b	pre-mRNA processing factor 4B	13	34875528	BB344827	19134	28	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleus spliceosomal complex chromosome mRNA processing protein phosphorylation protein phosphorylation RNA splicing kinase activity phosphorylation nuclear speck transferase activity mRNA cis splicing, via spliceosome catalytic step 2 spliceosome
1419669_at	Prtn3	proteinase 3	10	79879666	U97073	19152	39	serine-type endopeptidase activity serine-type endopeptidase activity signaling receptor binding protein binding extracellular region extracellular space lysosome cytosol plasma membrane proteolysis proteolysis membrane protein ectodomain proteolysis peptidase activity serine-type peptidase activity membrane hydrolase activity enzyme binding collagen catabolic process azurophil granule lumen intracellular membrane-bounded organelle positive regulation of GTPase activity plasma membrane raft cell-cell junction maintenance negative regulation of phagocytosis neutrophil extravasation mature conventional dendritic cell differentiation
1417385_at	Npepps	aminopeptidase puromycin sensitive	11	-97205841	AK010446	19155	45	aminopeptidase activity extracellular space nucleus cytoplasm cytoplasm cytosol proteolysis proteolysis peptidase activity metallopeptidase activity zinc ion binding zinc ion binding membrane hydrolase activity peptide binding peptide catabolic process metal ion binding metalloaminopeptidase activity cellular response to hypoxia
1418183_a_at	Cyth1	cytohesin 1	11	-118164169, -118164169, -118181100, -118164169, -118181100	AB013464	19157	34	guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm cytosol plasma membrane plasma membrane bicellular tight junction lipid binding cytoplasmic side of plasma membrane membrane neuromuscular junction regulation of ARF protein signal transduction anchoring junction establishment of epithelial cell polarity extrinsic component of presynaptic membrane presynaptic modulation of chemical synaptic transmission
1421410_a_at	Pstpip2	proline-serine-threonine phosphatase-interacting protein 2	18	77794549	BC002123	19201	43	actin binding protein binding cytoplasm cytoplasm cytosol cytoskeleton actin filament plasma membrane cytoskeleton organization membrane actin filament polymerization actin filament binding
1428853_at	Ptch1	patched 1	13	-63508327, -63508327	BG071079	19206	1421	negative regulation of transcription by RNA polymerase II branching involved in ureteric bud morphogenesis in utero embryonic development cell fate determination neural tube formation neural tube closure heart morphogenesis patched binding smoothened binding smoothened binding protein binding extracellular region Golgi apparatus plasma membrane plasma membrane plasma membrane plasma membrane caveola cilium signal transduction regulation of mitotic cell cycle pattern specification process brain development hedgehog receptor activity hedgehog receptor activity heparin binding zinc ion binding negative regulation of cell population proliferation epidermis development animal organ morphogenesis dorsal/ventral pattern formation epidermal cell fate specification response to chlorate negative regulation of keratinocyte proliferation positive regulation of cholesterol efflux cholesterol binding cholesterol binding membrane protein processing spinal cord motor neuron differentiation neural tube patterning dorsal/ventral neural tube patterning neural plate axis specification embryonic limb morphogenesis embryonic limb morphogenesis cyclin binding cyclin binding midbody mammary gland development regulation of protein localization regulation of protein localization limb morphogenesis hindlimb morphogenesis regulation of growth negative regulation of multicellular organism growth regulation of cell population proliferation glucose homeostasis intracellular membrane-bounded organelle negative regulation of DNA-binding transcription factor activity keratinocyte proliferation dendritic growth cone axonal growth cone protein-containing complex binding apical part of cell positive regulation of epidermal cell differentiation negative regulation of osteoblast differentiation negative regulation of smoothened signaling pathway negative regulation of smoothened signaling pathway negative regulation of smoothened signaling pathway negative regulation of smoothened signaling pathway negative regulation of smoothened signaling pathway negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription perinuclear region of cytoplasm embryonic organ development epithelial cell proliferation negative regulation of epithelial cell proliferation negative regulation of cell division pharyngeal system development mammary gland duct morphogenesis mammary gland epithelial cell differentiation cell differentiation involved in kidney development somite development somite development cellular response to cholesterol cellular response to cholesterol commissural neuron axon guidance stem cell proliferation cell proliferation involved in metanephros development protein localization to plasma membrane hedgehog family protein binding hedgehog family protein binding negative regulation of stem cell proliferation	04340 05200 05217
1416249_at	Nadk	NAD kinase	4	155563814, 155562380	AW538068	192185	26	nucleotide binding NAD+ kinase activity NAD+ kinase activity NAD+ kinase activity ATP binding cytosol NADP biosynthetic process NADP biosynthetic process kinase activity phosphorylation transferase activity NAD metabolic process positive regulation of insulin secretion involved in cellular response to glucose stimulus metal ion binding	00760 01100
1450071_at	Ash1l	ASH1 like histone lysine methyltransferase	3	88965811	BG694892	192195	45	MAPK cascade skeletal system development negative regulation of acute inflammatory response DNA binding chromatin binding nucleus nucleoplasm nucleoplasm chromosome Golgi apparatus bicellular tight junction chromatin organization regulation of DNA-templated transcription transcription by RNA polymerase II inflammatory response single fertilization methyltransferase activity post-embryonic development regulation of gene expression macrophage cytokine production transferase activity flagellated sperm motility methylation interleukin-6 production histone methyltransferase activity histone H3K4 methyltransferase activity histone H3K4 methyltransferase activity histone H3K4 methyltransferase activity negative regulation of MAPK cascade positive regulation of transcription by RNA polymerase II decidualization metal ion binding histone H3K9 methyltransferase activity histone H3K36 methyltransferase activity sebaceous gland development negative regulation of inflammatory response uterus morphogenesis anchoring junction histone H3K9 monomethyltransferase activity histone H3K36 trimethyltransferase activity tarsal gland development uterine gland development	00310 04530
1436766_at	Luc7l2	LUC7-like 2 (S. cerevisiae)	6	38555722, 38551333, 38551333	BB475271	192196	30	mRNA binding mRNA binding nucleus U1 snRNP U1 snRNP mRNA splice site recognition mRNA splice site recognition nuclear speck enzyme binding U2-type prespliceosome
1436448_a_at	Ptgs1	prostaglandin-endoperoxide synthase 1	2	36230425	AA833146	19224	318	prostaglandin biosynthetic process prostaglandin biosynthetic process photoreceptor outer segment peroxidase activity prostaglandin-endoperoxide synthase activity prostaglandin-endoperoxide synthase activity nuclear envelope cytoplasm cytoplasm cytoplasm endoplasmic reticulum Golgi apparatus lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process prostaglandin metabolic process response to oxidative stress learning memory regulation of blood pressure negative regulation of norepinephrine secretion membrane oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen cyclooxygenase pathway cyclooxygenase pathway heme binding keratinocyte differentiation negative regulation of epinephrine secretion maintenance of blood-brain barrier regulation of cell population proliferation neuron projection intracellular membrane-bounded organelle positive regulation of vasoconstriction positive regulation of smooth muscle contraction metal ion binding dioxygenase activity	00590 01100
1419657_a_at	Slc25a36	solute carrier family 25, member 36	9	-97077010	BB503267	192287	23	mitochondrial genome maintenance mitochondrial genome maintenance mitochondrion mitochondrion mitochondrion mitochondrial inner membrane pyrimidine nucleotide transport mitochondrion organization pyrimidine nucleotide transmembrane transporter activity pyrimidine nucleotide transmembrane transporter activity membrane regulation of mitochondrial membrane potential transmembrane transport pyrimidine nucleotide import into mitochondrion
1417219_s_at	Tmsb10	thymosin beta 10	6	-72957346, -72957346, -72957346	NM_025284	19240	36	actin monomer binding actin monomer binding cytoplasm cytoplasm actin cytoskeleton organization regulation of cell migration sequestering of actin monomers
1448830_at	Dusp1	dual specificity phosphatase 1	17	-26505590	NM_013642	19252	233	endoderm formation phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity nucleus nucleus cytoplasm cytoplasm protein dephosphorylation cell cycle negative regulation of cell adhesion protein tyrosine/serine/threonine phosphatase activity negative regulation of cell population proliferation protein tyrosine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity dephosphorylation hydrolase activity phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity myosin phosphatase activity growth factor binding MAP kinase tyrosine phosphatase activity peptidyl-tyrosine dephosphorylation peptidyl-tyrosine dephosphorylation peptidyl-tyrosine dephosphorylation intracellular signal transduction peptidyl-threonine dephosphorylation positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of MAP kinase activity negative regulation of MAPK cascade mitogen-activated protein kinase binding mitogen-activated protein kinase binding peptidyl-serine dephosphorylation negative regulation of ERK1 and ERK2 cascade negative regulation of monocyte chemotaxis negative regulation of p38MAPK cascade negative regulation of p38MAPK cascade cellular response to chemokine negative regulation of DNA biosynthetic process	04010
1448511_at	Ptprcap	protein tyrosine phosphatase receptor type C polypeptide-associated protein	19	4154645	NM_016933	19265	30	plasma membrane plasma membrane membrane
1418539_a_at	Ptpre	protein tyrosine phosphatase receptor type E	7	135651898, 135593480, 135537823, 135605827	U35368	19267	54	phosphoprotein phosphatase activity protein tyrosine phosphatase activity protein tyrosine phosphatase activity nucleus cytoplasm cytoplasm plasma membrane plasma membrane protein dephosphorylation protein dephosphorylation transmembrane receptor protein tyrosine phosphatase signaling pathway membrane dephosphorylation hydrolase activity phosphatase activity regulation of mast cell activation identical protein binding negative regulation of insulin receptor signaling pathway negative regulation of insulin receptor signaling pathway
1438828_at	Rapgef6	Rap guanine nucleotide exchange factor (GEF) 6	11	54596145, 54596145, 54522844	BM243959	192786	25	guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity centrosome cytosol plasma membrane plasma membrane Ras protein signal transduction apical plasma membrane apical plasma membrane microvillus assembly endocytic vesicle endocytic vesicle GTP-dependent protein binding small GTPase binding positive regulation of GTPase activity positive regulation of GTPase activity phosphatidic acid binding protein localization to plasma membrane
1416082_at	Rab1a	RAB1A, member RAS oncogene family	11	20201411	AW108405	19324	92	autophagosome assembly autophagosome assembly Golgi membrane nucleotide binding GTPase activity GTPase activity G protein activity protein binding GTP binding cytoplasm endosome early endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus intracellular protein transport intracellular protein transport endoplasmic reticulum to Golgi vesicle-mediated transport endocytosis autophagy Golgi organization endomembrane system protein transport membrane vesicle-mediated transport cell migration cell migration hydrolase activity virion assembly growth hormone secretion melanosome transport positive regulation of interleukin-8 production substrate adhesion-dependent cell spreading melanosome defense response to bacterium neuronal cell body synapse vesicle transport along microtubule COPII-coated vesicle cargo loading presynapse positive regulation of glycoprotein metabolic process
1438097_at	Rab20	RAB20, member RAS oncogene family	8	-11453389	BG066967	19332	33	nucleotide binding GTPase activity GTPase activity GTP binding Golgi apparatus intracellular protein transport endomembrane system protein transport membrane cytoplasmic vesicle intracellular membrane-bounded organelle phagocytic vesicle phagocytic vesicle cellular response to type II interferon phagosome acidification phagosome-lysosome fusion
1418890_a_at	Rab3d	RAB3D, member RAS oncogene family	9	-21907491	BB349707	19340	61	nucleotide binding GTPase activity GTPase activity protein binding GTP binding mitochondrion endosome cytoplasmic microtubule plasma membrane plasma membrane exocytosis vesicle docking involved in exocytosis synaptic vesicle protein secretion protein transport membrane regulation of exocytosis regulation of exocytosis peptidyl-cysteine methylation GTP-dependent protein binding myosin V binding myosin V binding zymogen granule bone resorption protein localization to plasma membrane secretory vesicle positive regulation of regulated secretory pathway	04972
1440208_at	Rac2	Rac family small GTPase 2	15	-78559168	BE691393	19354	153	nucleotide binding GTPase activity GTPase activity protein binding GTP binding GTP binding nuclear envelope cytoplasm cytosol actin filament plasma membrane chemotaxis chemotaxis actin filament organization actin filament organization signal transduction G protein-coupled receptor signaling pathway small GTPase-mediated signal transduction cell population proliferation cell population proliferation positive regulation of lamellipodium assembly positive regulation of lamellipodium assembly positive regulation of lamellipodium assembly regulation of cell-substrate adhesion membrane protein kinase regulator activity lamellipodium cell projection assembly actin cytoskeleton organization actin cytoskeleton organization regulation of cell migration regulation of T cell proliferation erythrocyte enucleation regulation of mast cell degranulation bone resorption regulation of respiratory burst regulation of mast cell chemotaxis mast cell proliferation mast cell proliferation positive regulation of mast cell proliferation positive regulation of mast cell proliferation lymphocyte aggregation positive regulation of neutrophil chemotaxis positive regulation of neutrophil chemotaxis regulation of neutrophil migration	04010 04062 04310 04360 04370 04510 04520 04650 04662 04664 04666 04670 04810 05200 05210 05212 05416
1434295_at	Rasgrp1	RAS guanyl releasing protein 1	2	-117279983	BE691356	19419	85	positive regulation of protein phosphorylation inflammatory response to antigenic stimulus guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity calcium ion binding cytoplasm endoplasmic reticulum Golgi apparatus cytosol cytosol plasma membrane plasma membrane plasma membrane small GTPase-mediated signal transduction Ras protein signal transduction zinc ion binding membrane diacylglycerol binding natural killer cell activation cell differentiation phosphatidylcholine binding secretory granule localization positive regulation of granulocyte macrophage colony-stimulating factor production positive regulation of type II interferon production positive regulation of tumor necrosis factor production mast cell cytokine production positive regulation of natural killer cell activation positive regulation of natural killer cell differentiation positive regulation of T cell differentiation in thymus T cell proliferation B cell proliferation T cell activation B cell activation identical protein binding mast cell degranulation positive regulation of MAP kinase activity positive regulation of GTPase activity positive regulation of GTPase activity positive regulation of natural killer cell mediated cytotoxicity positive regulation of JNK cascade positive regulation of Ras protein signal transduction metal ion binding vesicle transport along microtubule regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade activation of GTPase activity activation of GTPase activity	04010 04660
1426863_at	Rbmx	RNA binding motif protein, X chromosome	X	-57383347, -57386029	BM123721	19655	36	regulation of alternative mRNA splicing, via spliceosome euchromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding nucleic acid binding chromatin binding RNA binding RNA binding single-stranded RNA binding mRNA binding nucleus spliceosomal complex spliceosomal complex transcription by RNA polymerase II mRNA splice site recognition mRNA processing membrane protein ectodomain proteolysis RNA splicing postsynaptic density protein domain specific binding protein-containing complex identical protein binding supraspliceosomal complex positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of mRNA splicing, via spliceosome extracellular exosome catalytic step 2 spliceosome cellular response to interleukin-1 glutamatergic synapse regulation of postsynapse organization ribonucleoprotein complex	03040
1436196_at	Rel	reticuloendotheliosis oncogene	11	-23736849	BE691546	19696	259	RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific cytokine production DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus cytoplasm cytoplasm regulation of DNA-templated transcription inflammatory response canonical NF-kappaB signal transduction negative regulation of gene expression negative regulation of interferon-beta production positive regulation of interleukin-12 production cellular response to stress response to cytokine non-canonical NF-kappaB signal transduction sequence-specific DNA binding innate immune response positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II
1424632_a_at	Rev3l	REV3 like, DNA directed polymerase zeta catalytic subunit	10	39732159	AB031049	19714	59	nucleotide binding double-strand break repair via homologous recombination nucleic acid binding DNA binding DNA-directed DNA polymerase activity DNA-directed DNA polymerase activity nucleus nucleus nucleolus DNA replication DNA repair DNA damage response zeta DNA polymerase complex zeta DNA polymerase complex transferase activity nucleotidyltransferase activity translesion synthesis error-prone translesion synthesis error-prone translesion synthesis metal ion binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding	01100
1448101_s_at	Trim27	tripartite motif-containing 27	13	21179930	NM_009054	19720	59	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II fibrillar center negative regulation of adaptive immune response DNA binding transcription coactivator activity ubiquitin-protein transferase activity protein binding nucleus nucleoplasm nucleolus cytoplasm cytoplasm cytoplasm mitochondrion endosome negative regulation of protein kinase activity zinc ion binding negative regulation of autophagy transferase activity SUMO transferase activity retromer complex nuclear membrane negative regulation of type I interferon production negative regulation of interleukin-2 production negative regulation of tumor necrosis factor production positive regulation of type II interferon production negative regulation of viral transcription negative regulation of viral transcription negative regulation of viral transcription Arp2/3 complex-mediated actin nucleation retrograde transport, endosome to Golgi identical protein binding suppression of viral release by host innate immune response innate immune response innate immune response negative regulation of gene expression, epigenetic metal ion binding positive regulation of DNA-binding transcription factor activity positive regulation of actin nucleation ubiquitin protein ligase activity ubiquitin protein ligase activity protein K63-linked ubiquitination protein K63-linked ubiquitination negative regulation of calcium ion import
1437375_at	Rfx3	regulatory factor X, 3 (influences HLA class II expression)	19	-27761720, -27761720	BB745175	19726	61	chromatin chromatin transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus transcription regulator complex DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II multicellular organism development determination of left/right symmetry cell differentiation endocrine pancreas development sequence-specific DNA binding negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II cell maturation regulation of insulin secretion cilium assembly cilium-dependent cell motility epithelial cilium movement involved in determination of left/right asymmetry type B pancreatic cell maturation sequence-specific double-stranded DNA binding positive regulation of type B pancreatic cell development
1448948_at	Slc50a1	solute carrier family 50 (sugar transporter), member 1	3	-89268245	NM_009057	19729	20	Golgi apparatus plasma membrane carbohydrate transport carbohydrate transport endomembrane system membrane glucoside transmembrane transporter activity sugar transmembrane transporter activity sugar transmembrane transporter activity
1450688_at	Rgl2	ral guanine nucleotide dissociation stimulator-like 2	17	33929893	NM_009059	19732	24	guanyl-nucleotide exchange factor activity signal transduction small GTPase-mediated signal transduction negative regulation of cardiac muscle cell apoptotic process regulation of Ral protein signal transduction positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
1448852_at	Rgn	regucalcin	X	20549817	NM_009060	19733	83	negative regulation of protein phosphorylation gluconolactonase activity gluconolactonase activity gluconolactonase activity gluconolactonase activity calcium ion binding calcium ion binding nucleus cytoplasm intracellular calcium ion homeostasis spermatogenesis zinc ion binding positive regulation of triglyceride biosynthetic process positive regulation of glucose metabolic process hydrolase activity L-ascorbic acid biosynthetic process L-ascorbic acid biosynthetic process L-ascorbic acid biosynthetic process enzyme regulator activity negative regulation of apoptotic process negative regulation of nitric oxide biosynthetic process positive regulation of fatty acid biosynthetic process metal ion binding negative regulation of epithelial cell proliferation regulation of calcium-mediated signaling negative regulation of flagellated sperm motility negative regulation of RNA biosynthetic process negative regulation of bone development positive regulation of proteolysis involved in protein catabolic process negative regulation of DNA catabolic process negative regulation of DNA biosynthetic process
1419273_at	Uri1	URI1, prefoldin-like chaperone	7	-37959991	AV278756	19777	36	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II complex binding regulation of cell growth chromatin binding chromatin binding transcription corepressor activity transcription corepressor activity protein phosphatase inhibitor activity nucleus nucleoplasm cytoplasm mitochondrion cytosol regulation of transcription by RNA polymerase II response to virus negative regulation of phosphatase activity negative regulation of phosphatase activity phosphatase inhibitor activity cell projection phosphoprotein binding cellular response to growth factor stimulus cellular response to steroid hormone stimulus RPAP3/R2TP/prefoldin-like complex negative regulation of intrinsic apoptotic signaling pathway
1419311_at	Trim10	tripartite motif-containing 10	17	36869573	NM_011280	19824	20	protein binding cytoplasm cytoplasm zinc ion binding protein ubiquitination erythrocyte differentiation innate immune response innate immune response negative regulation of viral entry into host cell metal ion binding ubiquitin protein ligase activity
1419586_at	Rp2	retinitis pigmentosa 2 homolog	X	20364480, 20364480	BF168611	19889	27	nucleotide binding magnesium ion binding GTPase activator activity GTPase activator activity GTP binding nucleoplasm cytoplasm Golgi apparatus centriole plasma membrane plasma membrane cilium cilium post-Golgi vesicle-mediated transport post-Golgi vesicle-mediated transport protein transport membrane nuclear body cytoplasmic vesicle ciliary basal body ciliary basal body cell projection periciliary membrane compartment periciliary membrane compartment
1436699_x_at	Rpl18	ribosomal protein L18	7	45718070	BB422726	19899	42	cytoplasmic translation cytoplasmic translation RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome nucleolus cytoplasm endoplasmic reticulum cytosol cytosol ribosome translation cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome synapse ribonucleoprotein complex	03010
1448398_s_at	Rpl22	ribosomal protein L22	4	152324435, 152325725	NM_009079	19934	248	cytoplasmic translation RNA binding RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome nucleus cytoplasm cytosol ribosome ribosome ribosome ribosome ribosome translation heparin binding cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome identical protein binding synapse synapse alpha-beta T cell differentiation presynapse presynapse postsynapse glutamatergic synapse glutamatergic synapse glutamatergic synapse translation at presynapse translation at presynapse translation at presynapse translation at postsynapse ribonucleoprotein complex	03010
1455195_at	Rps24	ribosomal protein S24	14	24490752, 24490677	BM119287	20088	39	cytoplasmic translation structural constituent of ribosome structural constituent of ribosome nucleus cytoplasm endoplasmic reticulum cytosol cytosol ribosome rRNA processing translation small ribosomal subunit cytosolic ribosome cytosolic small ribosomal subunit cytosolic small ribosomal subunit cytosolic small ribosomal subunit translation initiation factor binding small-subunit processome erythrocyte homeostasis ribosomal small subunit biogenesis synapse synapse synapse presynapse postsynapse translation at presynapse translation at postsynapse ribonucleoprotein complex	03010
1417542_at	Rps6ka2	ribosomal protein S6 kinase, polypeptide 2	17	7170114	BB737182	20112	61	nucleotide binding magnesium ion binding oocyte maturation brain renin-angiotensin system protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ribosomal protein S6 kinase activity ribosomal protein S6 kinase activity protein serine/threonine/tyrosine kinase activity protein binding ATP binding nucleus nucleoplasm nucleoplasm nucleoplasm cytoplasm cytoplasm cytoplasm spindle protein phosphorylation heart development negative regulation of cell population proliferation positive regulation of gene expression cardiac muscle cell apoptotic process kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-serine phosphorylation intracellular signal transduction positive regulation of apoptotic process negative regulation of cell cycle negative regulation of meiotic nuclear division heart contraction regulation of protein processing cellular response to carbohydrate stimulus meiotic spindle	04010 04114 04150 04720 04722 04914
1451860_a_at	Trim30a	tripartite motif-containing 30A	7	-104409025, -104409025	AF220015	20128	39	protein polyubiquitination P-body activation of innate immune response DNA binding transcription coactivator activity ubiquitin-protein transferase activity nucleus nucleoplasm cytoplasm cytoplasm cytoplasm cytosol autophagy zinc ion binding response to bacterium positive regulation of autophagy protein kinase binding protein kinase binding protein-macromolecule adaptor activity regulation of lipopolysaccharide-mediated signaling pathway negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production regulation of protein localization regulation of protein localization negative regulation of toll-like receptor signaling pathway pattern recognition receptor activity identical protein binding protein homodimerization activity protein homodimerization activity positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of MAPK cascade suppression of viral release by host innate immune response innate immune response positive regulation of protein catabolic process regulation of viral entry into host cell negative regulation of viral entry into host cell positive regulation of viral entry into host cell metal ion binding positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity protein autoubiquitination ubiquitin protein ligase activity protein K63-linked ubiquitination negative regulation of NLRP3 inflammasome complex assembly omegasome negative regulation of reactive oxygen species metabolic process
1434437_x_at	Rrm2	ribonucleotide reductase M2	12	24708253	AV301324	20135	81	blastocyst development ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor protein binding nucleus nuclear envelope cytoplasm cytosol cytosol ribonucleoside-diphosphate reductase complex ribonucleoside-diphosphate reductase complex ribonucleoside-diphosphate reductase complex ferric iron binding ribonucleoside diphosphate metabolic process ribonucleoside diphosphate metabolic process deoxyribonucleotide metabolic process deoxyribonucleotide biosynthetic process deoxyribonucleotide biosynthetic process 2'-deoxyribonucleotide biosynthetic process 2'-deoxyribonucleotide biosynthetic process oxidoreductase activity identical protein binding protein homodimerization activity metal ion binding protein heterotetramerization positive regulation of G1/S transition of mitotic cell cycle	00230 00240 00480 01100 04115
1460351_at	S100a11	S100 calcium binding protein A11	3	93520495	BC021916	20195	43	ruffle calcium ion binding calcium ion binding extracellular space nucleus cytoplasm cytoplasm cytoplasm positive regulation of smooth muscle cell migration regulation of cell population proliferation protein homodimerization activity S100 protein binding S100 protein binding metal ion binding calcium-dependent protein binding calcium-dependent protein binding collagen-containing extracellular matrix
1421375_a_at	S100a6	S100 calcium binding protein A6 (calcyclin)	3	90612893	NM_011313	20200	93	ruffle calcium ion binding calcium ion binding calcium ion binding protein binding tropomyosin binding nucleus nucleus nuclear envelope cytoplasm cytosol plasma membrane zinc ion binding cytoplasmic side of plasma membrane monoatomic ion transmembrane transporter activity membrane protein homodimerization activity S100 protein binding S100 protein binding metal ion binding calcium-dependent protein binding calcium-dependent protein binding perinuclear region of cytoplasm perinuclear region of cytoplasm collagen-containing extracellular matrix
1419394_s_at	S100a8	S100 calcium binding protein A8 (calgranulin A)	3	90669070	NM_013650	20201	177	immune system process leukocyte migration involved in inflammatory response leukocyte migration involved in inflammatory response peptide secretion peptide secretion positive regulation of peptide secretion positive regulation of peptide secretion calcium ion binding calcium ion binding extracellular region extracellular space cytoplasm cytosol cytoskeleton plasma membrane autophagy apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process chemotaxis inflammatory response astrocyte development membrane antioxidant activity peptidyl-cysteine S-nitrosylation neutrophil chemotaxis neutrophil chemotaxis response to lipopolysaccharide regulation of toll-like receptor signaling pathway autocrine signaling innate immune response intermediate filament cytoskeleton metal ion binding calcium-dependent protein binding positive regulation of inflammatory response neutrophil aggregation neutrophil aggregation calprotectin complex positive regulation of intrinsic apoptotic signaling pathway
1448756_at	S100a9	S100 calcium binding protein A9 (calgranulin B)	3	-90692629	NM_009114	20202	253	cornified envelope immune system process leukocyte migration involved in inflammatory response leukocyte migration involved in inflammatory response chronic inflammatory response peptide secretion peptide secretion positive regulation of peptide secretion positive regulation of peptide secretion calcium ion binding calcium ion binding extracellular region extracellular space cytoplasm cytoplasm cytoskeleton plasma membrane regulation of translation autophagy apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process chemotaxis inflammatory response positive regulation of neuron projection development astrocyte development astrocyte development membrane antioxidant activity peptidyl-cysteine S-nitrosylation peptidyl-cysteine S-nitrosylation actin cytoskeleton organization positive regulation of blood coagulation neutrophil chemotaxis neutrophil chemotaxis leukocyte chemotaxis response to lipopolysaccharide regulation of toll-like receptor signaling pathway autocrine signaling autocrine signaling peptidyl-cysteine S-trans-nitrosylation modulation of process of another organism endothelial cell migration innate immune response regulation of integrin biosynthetic process regulation of integrin biosynthetic process metal ion binding calcium-dependent protein binding positive regulation of inflammatory response regulation of respiratory burst involved in inflammatory response antimicrobial humoral immune response mediated by antimicrobial peptide antimicrobial humoral immune response mediated by antimicrobial peptide neutrophil aggregation neutrophil aggregation calprotectin complex S100A9 complex positive regulation of intrinsic apoptotic signaling pathway
1450788_at	Saa1	serum amyloid A 1	7	-46740496	NM_009117	20208	104	G protein-coupled receptor binding protein binding extracellular region extracellular space cytoplasmic microtubule acute-phase response heparin binding cholesterol metabolic process response to bacterium high-density lipoprotein particle
1450826_a_at	Saa3	serum amyloid A 3	7	-46711997	NM_011315	20210	86	extracellular region extracellular space acute-phase response I-kappaB phosphorylation response to bacterium high-density lipoprotein particle response to stilbenoid Toll-like receptor 4 binding chemoattractant activity cell chemotaxis cellular response to interleukin-1
1437389_x_at	Khdrbs1	KH domain containing, RNA binding, signal transduction associated 1	4	-129703168, -129713814	AV117555	20218	112	negative regulation of transcription by RNA polymerase II regulation of alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome nucleic acid binding RNA binding RNA binding mRNA binding protein binding nucleus nucleus nucleus nucleoplasm cytoplasm mRNA processing cell cycle cell surface receptor signaling pathway cell surface receptor signaling pathway poly(A) binding poly(A) binding poly(U) RNA binding membrane SH3 domain binding protein domain specific binding protein-containing complex signaling adaptor activity signaling adaptor activity SH2 domain binding identical protein binding identical protein binding protein-containing complex binding positive regulation of translational initiation regulation of RNA export from nucleus positive regulation of RNA export from nucleus regulation of mRNA splicing, via spliceosome T cell receptor signaling pathway Grb2-Sos complex protein tyrosine kinase binding protein tyrosine kinase binding
1419059_at	Apcs	amyloid P component, serum	1	-172893960	NM_011318	20219	82	complement component C1q complex binding complement component C1q complex binding calcium ion binding extracellular region extracellular space extracellular space carbohydrate binding protein-containing complex identical protein binding negative regulation by host of viral exo-alpha-sialidase activity negative regulation by host of viral glycoprotein metabolic process innate immune response innate immune response negative regulation of monocyte differentiation negative regulation of viral entry into host cell virion binding metal ion binding negative regulation of viral process protein-containing complex assembly negative regulation of exo-alpha-sialidase activity negative regulation of glycoprotein metabolic process
1416008_at	Satb1	special AT-rich sequence binding protein 1	17	-51736186, -51736186, -51736186, -51736186, -51736186	AV172776	20230	111	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin heterochromatin RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding chromatin binding DNA-binding transcription factor activity nucleus nucleoplasm chromatin organization chromatin remodeling chromatin remodeling regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II epidermis development nuclear matrix nuclear body PML body T cell activation CD4-positive, alpha-beta T cell differentiation CD8-positive, alpha-beta T cell differentiation sequence-specific DNA binding activated T cell proliferation reflex DNA-binding transcription factor binding
1415964_at	Scd1	stearoyl-Coenzyme A desaturase 1	19	-44394449	NM_009127	20249	287	stearoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity iron ion binding iron ion binding nucleolus endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process unsaturated fatty acid biosynthetic process unsaturated fatty acid biosynthetic process triglyceride metabolic process lipid biosynthetic process response to bacterium membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water palmitoyl-CoA 9-desaturase activity palmitoyl-CoA 9-desaturase activity palmitoyl-CoA 9-desaturase activity cholesterol homeostasis intracellular membrane-bounded organelle metal ion binding sebaceous gland development defense response to Gram-positive bacterium white fat cell differentiation brown fat cell differentiation lipid homeostasis sterol homeostasis response to fatty acid response to fatty acid positive regulation of cold-induced thermogenesis tarsal gland development monounsaturated fatty acid biosynthetic process monounsaturated fatty acid biosynthetic process monounsaturated fatty acid biosynthetic process monounsaturated fatty acid biosynthetic process	01040 03320
1415822_at	Scd2	stearoyl-Coenzyme A desaturase 2	19	44293675	BG060909	20250	57	stearoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity stearoyl-CoA 9-desaturase activity iron ion binding iron ion binding nucleolus endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane lipid metabolic process fatty acid metabolic process fatty acid biosynthetic process unsaturated fatty acid biosynthetic process unsaturated fatty acid biosynthetic process membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water palmitoyl-CoA 9-desaturase activity palmitoyl-CoA 9-desaturase activity palmitoyl-CoA 9-desaturase activity intracellular membrane-bounded organelle metal ion binding response to fatty acid response to fatty acid monounsaturated fatty acid biosynthetic process monounsaturated fatty acid biosynthetic process	01040 03320
1420764_at	Scrg1	scrapie responsive gene 1	8	57455922	NM_009136	20284	23	extracellular region cytoplasm Golgi apparatus Golgi apparatus neuron projection terminus neuron projection terminus
1448061_at	Msr1	macrophage scavenger receptor 1	8	-39581699, -39603451	AA183642	20288	264	amyloid-beta binding amyloid-beta binding scavenger receptor activity collagen trimer plasma membrane plasma membrane endocytosis receptor-mediated endocytosis phagocytosis, engulfment negative regulation of gene expression positive regulation of macrophage derived foam cell differentiation positive regulation of cholesterol storage positive regulation of cholesterol storage membrane low-density lipoprotein particle binding low-density lipoprotein particle binding cholesterol transport low-density lipoprotein particle plasma lipoprotein particle clearance plasma lipoprotein particle clearance cargo receptor activity lipoprotein transport establishment of localization in cell amyloid-beta clearance amyloid-beta clearance amyloid-beta clearance	04145
1449984_at	Cxcl2	C-X-C motif chemokine ligand 2	5	90903898	NM_009140	20310	178	response to molecule of bacterial origin cytokine activity extracellular region extracellular space extracellular space extracellular space chemotaxis defense response inflammatory response inflammatory response immune response positive regulation of cytosolic calcium ion concentration chemokine activity chemokine activity neutrophil chemotaxis neutrophil chemotaxis leukocyte chemotaxis CXCR chemokine receptor binding antimicrobial humoral immune response mediated by antimicrobial peptide chemokine-mediated signaling pathway cellular response to lipopolysaccharide	04060 04062 04621
1440173_x_at	Selp	selectin, platelet	1	164115263	BB224329	20344	395	lipopolysaccharide binding positive regulation of leukocyte migration positive regulation of leukocyte migration regulation of cellular extravasation calcium ion binding protein binding extracellular space extracellular space plasma membrane inflammatory response cell adhesion heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules leukocyte cell-cell adhesion leukocyte cell-cell adhesion heparin binding external side of plasma membrane external side of plasma membrane external side of plasma membrane positive regulation of platelet activation membrane calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules carbohydrate binding platelet alpha granule membrane regulation of integrin activation sialic acid binding sialic acid binding sialic acid binding response to cytokine calcium-mediated signaling using intracellular calcium source fucose binding positive regulation of cell adhesion metal ion binding calcium-dependent protein binding leukocyte migration leukocyte migration leukocyte migration leukocyte tethering or rolling leukocyte tethering or rolling leukocyte tethering or rolling positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction oligosaccharide binding oligosaccharide binding cellular response to interleukin-6 cell-cell adhesion positive regulation of leukocyte tethering or rolling	04514 05144 05150
1439768_x_at	Sema4f	sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain	6	-82911884	BB271145	20355	33	neural crest cell migration protein binding endoplasmic reticulum plasma membrane plasma membrane multicellular organism development nervous system development axon guidance axon guidance membrane cell differentiation semaphorin receptor binding semaphorin receptor binding positive regulation of cell migration negative regulation of axon extension retinal ganglion cell axon guidance cell projection synapse postsynaptic membrane chemorepellent activity axon extension negative regulation of axon extension involved in axon guidance negative chemotaxis semaphorin-plexin signaling pathway postsynaptic density membrane glutamatergic synapse	04360
1418747_at	Spi1	Spi-1 proto-oncogene	2	91096677, 91096699, 91082404	NM_011355	20375	445	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin chromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding cis-regulatory region sequence-specific DNA binding cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific vasculature development germinal center B cell differentiation follicular B cell differentiation lymphoid progenitor cell differentiation immature B cell differentiation defense response to tumor cell pro-T cell differentiation myeloid leukocyte differentiation myeloid leukocyte differentiation DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity RNA binding protein binding nucleus nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex transcription regulator complex regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transforming growth factor beta receptor signaling pathway multicellular organism development positive regulation of gene expression negative regulation of gene expression negative regulation of gene expression lymphocyte differentiation cell differentiation erythrocyte differentiation macrophage differentiation granulocyte differentiation lipopolysaccharide-mediated signaling pathway negative regulation of NF-kappaB transcription factor activity somatic stem cell population maintenance TRAIL-activated apoptotic signaling pathway histone deacetylase binding myeloid dendritic cell differentiation negative regulation of neutrophil degranulation sequence-specific DNA binding sequence-specific DNA binding negative regulation of MHC class II biosynthetic process positive regulation of B cell differentiation regulation of erythrocyte differentiation transcription initiation-coupled chromatin remodeling transcription initiation-coupled chromatin remodeling negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of DNA-binding transcription factor activity NFAT protein binding anatomical structure regression molecular adaptor activity RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II-specific DNA-binding transcription factor binding interleukin-6-mediated signaling pathway oncogene-induced cell senescence STAT family protein binding endothelial to hematopoietic transition negative regulation of protein localization to chromatin DNA-binding transcription factor binding DNA-binding transcription factor binding protein sequestering activity positive regulation of p38MAPK cascade negative regulation of non-canonical NF-kappaB signal transduction apoptotic process involved in blood vessel morphogenesis positive regulation of miRNA transcription positive regulation of miRNA transcription positive regulation of microglial cell mediated cytotoxicity negative regulation of adipose tissue development pericyte cell differentiation positive regulation of antifungal innate immune response regulation of myeloid progenitor cell differentiation positive regulation of myeloid dendritic cell chemotaxis	04380 05200 05221
1423130_a_at	Srsf5	serine and arginine-rich splicing factor 5	12	80945498	AW212917	20384	43	mRNA splicing, via spliceosome nucleic acid binding RNA binding RNA binding protein binding nucleus nucleoplasm nucleolus cytosol mRNA processing RNA splicing response to wounding nuclear speck nuclear speck response to insulin positive regulation of RNA splicing protein kinase B binding RS domain binding	03040
1423150_at	Scg5	secretogranin V	2	-113776312	AK019337	20394	54	enzyme inhibitor activity extracellular region nucleus intracellular protein transport neuropeptide signaling pathway peptide hormone processing secretory granule enzyme regulator activity regulation of hormone secretion regulation of hormone secretion unfolded protein binding
1449393_at	Sh2d1a	SH2 domain containing 1A	X	42502564, 42505321	NM_011364	20400	141	adaptive immune response immune system process protein binding cytoplasm humoral immune response cellular defense response cell-cell signaling natural killer cell mediated cytotoxicity natural killer cell mediated cytotoxicity innate immune response positive regulation of natural killer cell mediated cytotoxicity positive regulation of natural killer cell mediated cytotoxicity regulation of immune response negative regulation of T cell receptor signaling pathway	04650
1452246_at	Ostf1	osteoclast stimulating factor 1	19	-18580363	U58888	20409	34	cytoplasm signal transduction SH3 domain binding
1416329_at	Cyfip1	cytoplasmic FMR1 interacting protein 1	7	55842070	NM_011370	20430	73	RNA 7-methylguanosine cap binding RNA 7-methylguanosine cap binding cell morphogenesis actin binding protein binding profilin binding cytoplasm regulation of translation regulation of translation multicellular organism development nervous system development axon guidance regulation of cell shape positive regulation of lamellipodium assembly Rac protein signal transduction lamellipodium lamellipodium assembly lamellipodium assembly cell differentiation regulation of actin filament polymerization neuron projection development SCAR complex SCAR complex small GTPase binding regulation of myelination filopodium tip cellular response to insulin stimulus cell projection neuron projection neuron projection neuronal cell body terminal bouton dendritic spine dendritic growth cone axonal growth cone synapse synapse positive regulation of axon extension perinuclear region of cytoplasm axon extension positive regulation of axonogenesis cognition positive regulation of neurotrophin TRK receptor signaling pathway response to electrical stimulus excitatory synapse central region of growth cone peripheral region of growth cone dendrite extension postsynapse modification of synaptic structure modification of synaptic structure regulation of translation at postsynapse, modulating synaptic transmission regulation of translation at postsynapse, modulating synaptic transmission regulation of translation at postsynapse, modulating synaptic transmission regulation of translation at postsynapse, modulating synaptic transmission regulation of translation at postsynapse, modulating synaptic transmission positive regulation of dendrite development positive regulation of ruffle assembly negative regulation of synaptic vesicle recycling regulation of modification of postsynaptic actin cytoskeleton regulation of modification of postsynaptic actin cytoskeleton positive regulation of Arp2/3 complex-mediated actin nucleation	04810
1420928_at	St6gal1	beta galactoside alpha 2,6 sialyltransferase 1	16	23226020, 23290469, 23224739	BG075800	20440	87	Golgi trans cisterna Golgi membrane beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity beta-galactoside alpha-2,6-sialyltransferase activity extracellular region Golgi apparatus Golgi apparatus Golgi medial cisterna N-acetylneuraminate metabolic process protein glycosylation sialyltransferase activity sialyltransferase activity membrane transferase activity glycosyltransferase activity protein N-linked glycosylation via asparagine protein N-linked glycosylation via asparagine protein N-linked glycosylation via asparagine positive regulation of mononuclear cell proliferation protein homodimerization activity negative regulation of chemotaxis sialylation sialylation regulation of substrate adhesion-dependent cell spreading negative regulation of macrophage apoptotic process	00510 00514 01100
1425668_a_at	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	9	-35046575	AB061305	20443	50	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity beta-galactoside (CMP) alpha-2,3-sialyltransferase activity beta-galactoside (CMP) alpha-2,3-sialyltransferase activity Golgi apparatus protein glycosylation protein glycosylation protein glycosylation lipid metabolic process N-acetyllactosaminide alpha-2,3-sialyltransferase activity N-acetyllactosaminide alpha-2,3-sialyltransferase activity sialyltransferase activity glycoprotein biosynthetic process glycolipid biosynthetic process glycolipid biosynthetic process oligosaccharide biosynthetic process membrane transferase activity glycosyltransferase activity positive regulation of blood coagulation lipid glycosylation beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase cognition sialylation positive regulation of leukocyte tethering or rolling positive regulation of leukocyte tethering or rolling protein sialylation	00601 01100
1455695_at	St8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	6	-142821540	BI736113	20449	76	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Golgi apparatus protein glycosylation protein glycosylation N-glycan processing lipid metabolic process sphingolipid metabolic process cell population proliferation sialyltransferase activity oligosaccharide metabolic process membrane transferase activity glycosyltransferase activity cellular response to heat epithelial cell proliferation positive regulation of epithelial cell proliferation	00601 00603 00604 01100
1419186_a_at	St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	1	-95587681, -95627242	NM_009183	20452	66	ganglioside biosynthetic process alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Golgi apparatus protein glycosylation protein glycosylation N-glycan processing N-glycan processing sialyltransferase activity oligosaccharide metabolic process oligosaccharide metabolic process membrane transferase activity glycosyltransferase activity sialylation sialylation
1416206_at	Sipa1	signal-induced proliferation associated gene 1	19	-5651184	D11374	20469	35	epithelial cell morphogenesis GTPase activator activity GTPase activator activity nucleus cytoplasm cytoplasm Golgi apparatus plasma membrane membrane protein-containing complex cellular response to water deprivation regulation of small GTPase mediated signal transduction regulation of cell cycle establishment of epithelial cell polarity	04670
1418257_at	Slc12a7	solute carrier family 12, member 7	13	73763696, 73763659	BB732135	20499	40	plasma membrane monoatomic ion transport potassium ion transport cell volume homeostasis cell volume homeostasis chemical synaptic transmission ammonium transmembrane transporter activity symporter activity potassium:chloride symporter activity potassium:chloride symporter activity membrane protein kinase binding transmembrane transporter activity protein-containing complex chloride ion homeostasis potassium ion homeostasis transmembrane transport cellular response to glucose stimulus potassium ion transmembrane transport ammonium import across plasma membrane chloride transmembrane transport potassium ion import across plasma membrane	04966
1426599_a_at	Slc2a1	solute carrier family 2 (facilitated glucose transporter), member 1	4	119108744	BM209618	20525	408	Golgi membrane female germ cell nucleus photoreceptor inner segment female pronucleus long-chain fatty acid transporter activity glucose transmembrane transporter activity glucose transmembrane transporter activity protein binding intracellular anatomical structure cytoplasm cytoplasm cytosol plasma membrane plasma membrane caveola cell-cell junction central nervous system development carbohydrate transport intercalated disc long-chain fatty acid import across plasma membrane membrane membrane basolateral plasma membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane apical plasma membrane apical plasma membrane kinase binding transmembrane transporter activity Z disc midbody cortical actin cytoskeleton vesicle response to insulin dehydroascorbic acid transmembrane transporter activity dehydroascorbic acid transmembrane transporter activity cellular response to glucose starvation sarcolemma identical protein binding xenobiotic transport xenobiotic transmembrane transporter activity protein self-association membrane raft synapse glucose import glucose import D-glucose transmembrane transporter activity D-glucose transmembrane transporter activity D-glucose transmembrane transporter activity transmembrane transport protein-containing complex assembly dehydroascorbic acid transport dehydroascorbic acid transport dehydroascorbic acid transport glucose import across plasma membrane presynapse transport across blood-brain barrier glucose transmembrane transport glucose transmembrane transport glucose transporter complex	04920 04976 05200 05211
1455285_at	Slc31a1	solute carrier family 31, member 1	4	62360700	BB771765	20529	64	angiogenesis angiogenesis copper ion transmembrane transporter activity copper ion transmembrane transporter activity copper ion transmembrane transporter activity copper ion binding protein binding endosome late endosome plasma membrane plasma membrane monoatomic ion transport copper ion transport intracellular copper ion homeostasis intercalated disc silver ion transmembrane transporter activity silver ion transmembrane transporter activity copper ion import copper ion import copper ion import plasma membrane copper ion transport membrane basolateral plasma membrane apical plasma membrane apical plasma membrane early endosome membrane copper ion transmembrane transport vascular endothelial growth factor receptor-2 signaling pathway identical protein binding xenobiotic transport xenobiotic transport xenobiotic transmembrane transporter activity neuronal cell body protein complex oligomerization establishment of localization in cell recycling endosome recycling endosome membrane transmembrane transport cellular response to cisplatin copper ion import across plasma membrane silver ion transmembrane transport silver ion transmembrane transport
1416654_at	Slc31a2	solute carrier family 31, member 2	4	62291546, 62286428	NM_025286	20530	25	protein binding lysosome lysosomal membrane endosome late endosome plasma membrane monoatomic ion transport intracellular copper ion homeostasis intracellular copper ion homeostasis copper ion import membrane cytoplasmic vesicle late endosome membrane recycling endosome regulation of copper ion transmembrane transport
1417392_a_at	Slc7a7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7	14	-54369441, -54369441, -54369441, -54369441, -54369441	NM_011405	20540	30	regulation of arginine metabolic process regulation of arginine metabolic process amino acid transmembrane transport plasma membrane amino acid transport basic amino acid transmembrane transporter activity basic amino acid transmembrane transporter activity L-amino acid transmembrane transporter activity leucine transport membrane basolateral plasma membrane transmembrane transporter activity transmembrane transport L-arginine transmembrane transport basic amino acid transmembrane transport	04974
1418612_at	Slfn1	schlafen 1	11	83116819	NM_011407	20555	22	negative regulation of transcription by RNA polymerase II negative regulation of protein phosphorylation adaptive immune response immune system process RNA nuclease activity protein binding nucleus nucleus cytoplasm cytosol negative regulation of cell population proliferation T cell proliferation negative regulation of T cell proliferation ribosome binding regulation of cell cycle negative regulation of G1/S transition of mitotic cell cycle negative regulation of G1/S transition of mitotic cell cycle
1427102_at	Slfn4	schlafen 4	11	83175185	AF099975	20558	23	molecular_function RNA nuclease activity cellular_component nucleus cytosol response to bacterium ribosome binding
1448377_at	Slpi	secretory leukocyte peptidase inhibitor	2	-164354069	NM_011414	20568	66	immune system process DNA binding mRNA binding endopeptidase inhibitor activity endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity protein binding extracellular region extracellular space extracellular space extracellular space Golgi apparatus immune response negative regulation of peptidase activity antibacterial humoral response antibacterial humoral response antibacterial humoral response enzyme binding peptidase inhibitor activity negative regulation of protein binding response to lipopolysaccharide modulation of process of another organism defense response to bacterium negative regulation of viral genome replication innate immune response innate immune response
1421052_a_at	Sms	spermine synthase	X	-157443850, -157443850	NM_009214	20603	33	polyamine biosynthetic process spermine biosynthetic process spermine biosynthetic process spermine metabolic process S-adenosylmethionine-dependent methyltransferase activity transferase activity spermine synthase activity spermine synthase activity	00270 00330 00410 00480 01100
1429009_at	Snrnp70	small nuclear ribonucleoprotein 70 (U1)	7	-45376453	BI689977	20637	49	mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding mRNA binding nucleus nucleus nucleoplasm spliceosomal complex U1 snRNP U1 snRNP nuclear speck U1 snRNA binding U1 snRNA binding regulation of RNA splicing positive regulation of mRNA splicing, via spliceosome U2-type prespliceosome U1 snRNP binding ribonucleoprotein complex	03040
1420952_at	Son	Son DNA binding protein	16	91647823, 91647823	BB701473	20658	38	microtubule cytoskeleton organization mitotic cytokinesis nucleic acid binding DNA binding RNA binding RNA binding protein binding nucleus mRNA processing cell cycle RNA splicing nuclear speck negative regulation of apoptotic process regulation of RNA splicing regulation of mRNA splicing, via spliceosome regulation of mRNA splicing, via spliceosome RS domain binding regulation of cell cycle
1453003_at	Sorl1	sortilin-related receptor, LDLR class A repeats-containing	9	-41964708, -41964708	AK013519	20660	87	amyloid-beta binding diet induced thermogenesis transmembrane signaling receptor activity protein binding extracellular region extracellular space extracellular space nuclear envelope lumen nuclear envelope lumen endosome early endosome multivesicular body endoplasmic reticulum Golgi apparatus Golgi apparatus trans-Golgi network plasma membrane protein targeting protein targeting protein targeting to lysosome protein targeting to lysosome post-Golgi vesicle-mediated transport post-Golgi vesicle-mediated transport endocytosis receptor-mediated endocytosis neuropeptide signaling pathway multicellular organism development cell surface negative regulation of triglyceride catabolic process regulation of smooth muscle cell migration membrane membrane cell migration aspartic-type endopeptidase inhibitor activity aspartic-type endopeptidase inhibitor activity low-density lipoprotein particle binding negative regulation of BMP signaling pathway small GTPase binding negative regulation of protein-containing complex assembly cytoplasmic vesicle Golgi cisterna protein localization to Golgi apparatus insulin receptor recycling insulin receptor recycling neuropeptide binding neuronal cell body protein retention in Golgi apparatus protein retention in Golgi apparatus protein retention in Golgi apparatus positive regulation of protein catabolic process positive regulation of insulin receptor signaling pathway positive regulation of insulin receptor signaling pathway perinuclear region of cytoplasm negative regulation of neurogenesis protein maturation recycling endosome positive regulation of protein exit from endoplasmic reticulum perinucleolar compartment endosome to plasma membrane protein transport positive regulation of glial cell-derived neurotrophic factor production positive regulation of glial cell-derived neurotrophic factor production negative regulation of amyloid-beta formation negative regulation of amyloid-beta formation positive regulation of ER to Golgi vesicle-mediated transport positive regulation of early endosome to recycling endosome transport positive regulation of protein localization to early endosome negative regulation of amyloid precursor protein catabolic process negative regulation of amyloid precursor protein catabolic process negative regulation of neurofibrillary tangle assembly positive regulation of adipose tissue development positive regulation of adipose tissue development adaptive thermogenesis positive regulation of endocytic recycling
1433575_at	Sox4	SRY (sex determining region Y)-box 4	13	-28948919	BG083485	20677	201	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific pro-B cell differentiation mitral valve morphogenesis cardiac right ventricle morphogenesis atrial septum primum morphogenesis noradrenergic neuron differentiation DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex cytoplasm cytoplasm mitochondrion regulation of DNA-templated transcription regulation of DNA-templated transcription nervous system development brain development heart development positive regulation of cell population proliferation negative regulation of cell population proliferation gene expression glial cell proliferation spinal cord development glial cell development neuron differentiation T cell differentiation endocrine pancreas development negative regulation of protein ubiquitination regulation of protein stability positive regulation of insulin secretion somatic stem cell population maintenance miRNA binding ascending aorta morphogenesis glucose homeostasis positive regulation of apoptotic process regulation of DNA damage response, signal transduction by p53 class mediator positive regulation of gamma-delta T cell differentiation negative regulation of myoblast differentiation positive regulation of myoblast differentiation positive regulation of myoblast differentiation positive regulation of translation positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II sympathetic nervous system development camera-type eye morphogenesis protein stabilization protein stabilization ventricular septum morphogenesis mesenchyme development neuroepithelial cell differentiation kidney morphogenesis hematopoietic stem cell homeostasis cellular response to glucose stimulus positive regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway sequence-specific double-stranded DNA binding positive regulation of N-terminal peptidyl-lysine acetylation
1424923_at	Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	12	104236146, 104214453	BC002065	20715	30	adaptive immune response immune system process serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity extracellular space extracellular space nucleus cytoplasm apoptotic process negative regulation of peptidase activity negative regulation of endopeptidase activity peptidase inhibitor activity response to cytokine response to peptide hormone
1456615_a_at	Bptf	bromodomain PHD finger transcription factor	11	-107033080	AA867746	207165	58	negative regulation of transcription by RNA polymerase II chromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding embryonic placenta development nucleus nucleus nucleoplasm chromatin remodeling regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II brain development brain development endoderm development ATP-dependent activity, acting on DNA transcription factor binding anterior/posterior pattern specification NURF complex NURF complex dendrite methylated histone binding sequence-specific DNA binding cell body positive regulation of transcription by RNA polymerase II perinuclear region of cytoplasm ATPase complex
1422601_at	Serpinb9	serine (or cysteine) peptidase inhibitor, clade B, member 9	13	33004540	NM_009256	20723	41	T cell mediated cytotoxicity protease binding acute inflammatory response to antigenic stimulus serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity protein binding extracellular space extracellular space nucleus nucleoplasm cytoplasm cytoplasm cytoplasm Golgi apparatus cytosol immune response negative regulation of endopeptidase activity negative regulation of endopeptidase activity protection from natural killer cell mediated cytotoxicity defense response to bacterium cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process collagen-containing extracellular matrix negative regulation of T cell apoptotic process	05146
1434260_at	Fchsd2	FCH and double SH3 domains 2	7	101108774	BB461848	207278	20	protein binding phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm plasma membrane clathrin-coated pit endocytosis neuromuscular synaptic transmission lipid binding protein transport membrane regulation of actin filament polymerization positive regulation of actin filament polymerization neuromuscular junction cell projection phosphatidylinositol-3,4-bisphosphate binding recycling endosome membrane organization anchoring junction clathrin-dependent endocytosis stereocilium shaft positive regulation of Arp2/3 complex-mediated actin nucleation
1415794_a_at	Spin1	spindlin 1	13	51134317, 51100879, 51101546	BM228780	20729	40	DNA binding nucleus nucleoplasm nucleoplasm nucleolus cytoplasm spindle cytosol cytosol cytoskeleton chromatin organization regulation of DNA-templated transcription cell cycle female meiotic nuclear division multicellular organism development gamete generation rRNA transcription Wnt signaling pathway positive regulation of Wnt signaling pathway nuclear membrane methylated histone binding methylated histone binding positive regulation of DNA-templated transcription meiotic cell cycle
1438968_x_at	Spint2	serine protease inhibitor, Kunitz type 2	7	-29256329	AV058358	20733	44	neural tube closure neural tube closure serine-type endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity cytoplasm plasma membrane establishment or maintenance of cell polarity negative regulation of peptidase activity membrane negative regulation of cell-cell adhesion peptidase inhibitor activity epithelial cell morphogenesis involved in placental branching epithelial cell morphogenesis involved in placental branching basement membrane organization negative regulation of cell motility negative regulation of neural precursor cell proliferation
1426411_a_at	Strbp	spermatid perinuclear RNA binding protein	2	-37569867, -37569867, -37569867, -37569867	AK006314	20744	32	manchette RNA binding double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding nucleus cytoplasm cytoskeleton multicellular organism development spermatogenesis spermatid development mechanosensory behavior microtubule binding microtubule cytoskeleton tubulin binding cell differentiation cell motility
1449254_at	Spp1	secreted phosphoprotein 1	5	104435110, 104436191	NM_009263	20750	938	ossification osteoblast differentiation osteoblast differentiation cytokine activity integrin binding integrin binding extracellular region extracellular space extracellular space cytoplasm Golgi apparatus androgen catabolic process intracellular calcium ion homeostasis intracellular sodium ion homeostasis cell adhesion cell adhesion response to organic substance positive regulation of cell-substrate adhesion bone mineralization bone mineralization neutrophil chemotaxis neutrophil chemotaxis intracellular phosphate ion homeostasis intracellular chloride ion homeostasis biomineral tissue development vesicle response to vitamin D urate biosynthetic process small molecule binding cell projection negative regulation of apoptotic process ion binding apical part of cell positive regulation of bone resorption positive regulation of bone resorption positive regulation of DNA-templated transcription perinuclear region of cytoplasm response to steroid hormone extracellular matrix binding extracellular matrix binding calcium ion homeostasis cellular response to testosterone stimulus cellular response to fluid shear stress collecting duct development cellular response to leukemia inhibitory factor positive regulation of estradiol secretion	04510 04512 04620
1437378_x_at	Scarb1	scavenger receptor class B, member 1	5	-125277086, -125283319	BB224405	20778	393	lipopolysaccharide binding amyloid-beta binding phosphatidylserine binding lipopolysaccharide immune receptor activity endothelial cell proliferation scavenger receptor activity cytoplasm cytoplasm lysosome plasma membrane plasma membrane plasma membrane plasma membrane caveola caveola androgen biosynthetic process cholesterol catabolic process cholesterol catabolic process lipid transport phagocytosis, recognition high-density lipoprotein particle binding lipid binding cell surface cell surface positive regulation of triglyceride biosynthetic process positive regulation of cholesterol storage positive regulation of cholesterol storage regulation of phosphatidylcholine catabolic process phospholipid transport lipopolysaccharide transport membrane low-density lipoprotein particle binding low-density lipoprotein particle binding low-density lipoprotein particle binding cholesterol transport cholesterol transport microvillus membrane detection of lipopolysaccharide cholesterol efflux cholesterol efflux cholesterol efflux cholesterol efflux apolipoprotein binding apolipoprotein binding apolipoprotein A-I binding high-density lipoprotein particle remodeling plasma lipoprotein particle clearance low-density lipoprotein particle clearance high-density lipoprotein particle clearance high-density lipoprotein particle clearance vitamin transmembrane transport cholesterol homeostasis identical protein binding intracellular membrane-bounded organelle blood vessel endothelial cell migration recognition of apoptotic cell recognition of apoptotic cell recognition of apoptotic cell reverse cholesterol transport adhesion of symbiont to host carotenoid transport regulation of phagocytosis positive regulation of nitric-oxide synthase activity triglyceride homeostasis high-density lipoprotein particle receptor activity high-density lipoprotein particle receptor activity cholesterol import cholesterol import cholesterol import cholesterol import intestinal lipid absorption	04145 04975 04976 04977 05160
1428681_at	Usf3	upstream transcription factor family member 3	16	44173396	AK017426	207806	16	RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific negative regulation of epithelial to mesenchymal transition negative regulation of epithelial to mesenchymal transition positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II
1456500_at	Aph1b	aph1 homolog B, gamma secretase subunit	9	-66775486	AV232784	208117	35	Golgi membrane synaptic transmission, dopaminergic endoplasmic reticulum endoplasmic reticulum plasma membrane membrane protein ectodomain proteolysis Notch signaling pathway Notch signaling pathway Notch receptor processing Notch receptor processing Notch receptor processing short-term memory locomotory behavior positive regulation of endopeptidase activity membrane protein processing protein processing transport vesicle protein-macromolecule adaptor activity protein-macromolecule adaptor activity amyloid-beta formation amyloid-beta formation synaptic transmission, glutamatergic amyloid precursor protein catabolic process positive regulation of catalytic activity prepulse inhibition endopeptidase activator activity gamma-secretase complex gamma-secretase complex gamma-secretase complex gamma-secretase complex	04330 05010
1455107_at	Srpk1	serine/arginine-rich protein specific kinase 1	17	-28589587	BQ176926	20815	38	nucleotide binding spliceosomal complex assembly magnesium ion binding magnesium ion binding chromatin protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding ATP binding nucleus nucleus nucleoplasm nucleoplasm chromosome cytoplasm cytoplasm endoplasmic reticulum cytosol plasma membrane mRNA processing protein phosphorylation protein phosphorylation chromosome segregation RNA splicing kinase activity phosphorylation nuclear speck transferase activity peptidyl-serine phosphorylation cell differentiation intracellular signal transduction intracellular signal transduction intracellular signal transduction intracellular membrane-bounded organelle positive regulation of viral genome replication negative regulation of viral genome replication regulation of mRNA processing regulation of mRNA processing regulation of mRNA processing protein serine kinase activity
1455656_at	Btla	B and T lymphocyte associated	16	45224336	BM240873	208154	80	adaptive immune response immune system process immune response-regulating cell surface receptor signaling pathway immune response-regulating cell surface receptor signaling pathway protein binding plasma membrane plasma membrane cell surface receptor signaling pathway external side of plasma membrane membrane negative regulation of B cell proliferation signaling receptor activity signaling receptor activity negative regulation of T cell proliferation negative regulation of alpha-beta T cell proliferation
1450033_a_at	Stat1	signal transducer and activator of transcription 1	1	52119437, 52119621	AW214029	20846	996	chromatin RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription corepressor binding transcription coactivator binding negative regulation of endothelial cell proliferation positive regulation of defense response to virus by host DNA binding double-stranded DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity tumor necrosis factor receptor binding protein binding nucleus nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytoplasm cytosol cytosol DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II activation of cysteine-type endopeptidase activity involved in apoptotic process defense response signal transduction receptor signaling pathway via JAK-STAT receptor signaling pathway via JAK-STAT receptor signaling pathway via JAK-STAT cell population proliferation response to bacterium macrophage derived foam cell differentiation negative regulation of angiogenesis nuclear receptor binding cytokine-mediated signaling pathway enzyme binding axon dendrite lipopolysaccharide-mediated signaling pathway CCR5 chemokine receptor binding response to lipopolysaccharide positive regulation of interferon-alpha production protein-containing complex tumor necrosis factor-mediated signaling pathway negative regulation of macrophage fusion response to type I interferon response to type II interferon response to type II interferon histone acetyltransferase binding response to interferon-beta cellular response to interferon-beta interleukin-9-mediated signaling pathway regulation of cell population proliferation histone binding identical protein binding protein homodimerization activity negative regulation of canonical NF-kappaB signal transduction response to exogenous dsRNA response to peptide hormone sequence-specific DNA binding ubiquitin-like protein ligase binding positive regulation of erythrocyte differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II negative regulation by virus of viral protein levels in host cell perinuclear region of cytoplasm defense response to virus defense response to virus protein phosphatase 2A binding type II interferon-mediated signaling pathway type II interferon-mediated signaling pathway type I interferon-mediated signaling pathway type I interferon-mediated signaling pathway type I interferon-mediated signaling pathway renal tubule development interleukin-27-mediated signaling pathway ISGF3 complex cellular response to lipopolysaccharide cellular response to cytokine stimulus cellular response to type II interferon cellular response to organic cyclic compound RNA polymerase II transcription regulator complex promoter-specific chromatin binding	04062 04380 04620 04630 05140 05145 05160 05200 05212
1450403_at	Stat2	signal transducer and activator of transcription 2	10	128270497	AF088862	20847	139	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific regulation of protein phosphorylation DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus cytoplasm cytosol plasma membrane regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II defense response signal transduction receptor signaling pathway via JAK-STAT receptor signaling pathway via JAK-STAT regulation of cell population proliferation identical protein binding response to peptide hormone ubiquitin-like protein ligase binding positive regulation of transcription by RNA polymerase II defense response to virus type I interferon-mediated signaling pathway type I interferon-mediated signaling pathway type I interferon-mediated signaling pathway negative regulation of type I interferon-mediated signaling pathway negative regulation of type I interferon-mediated signaling pathway ISGF3 complex regulation of mitochondrial fission	04062 04380 04630 05160
1442083_at	Rsrc2	arginine/serine-rich coiled-coil 2	5	-123728425	BB036922	208606	22	molecular_function cellular_component biological_process
1419709_at	Stfa3	stefin A3	16	-36450536	NM_025288	20863	16	cornified envelope protease binding cysteine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity extracellular space nucleoplasm cytoplasm cytosol cytosol negative regulation of peptidase activity peptide cross-linking keratinocyte differentiation negative regulation of proteolysis cell-cell adhesion peptidase inhibitor complex
1427983_at	Zfp280c	zinc finger protein 280C	X	-48541625, -48541625	AI504060	208968	18	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus regulation of DNA-templated transcription metal ion binding
1437390_x_at	Stx1a	syntaxin 1A (brain)	5	135023481	AV339210	20907	209	SNARE binding SNARE binding SNARE binding acrosomal vesicle positive regulation of neurotransmitter secretion positive regulation of neurotransmitter secretion SNAP receptor activity SNAP receptor activity protein binding plasma membrane plasma membrane plasma membrane plasma membrane neurotransmitter transport intracellular protein transport intracellular protein transport exocytosis exocytosis synaptic vesicle synaptic vesicle voltage-gated potassium channel complex response to gravity positive regulation of norepinephrine secretion regulation of synaptic vesicle priming endomembrane system postsynaptic density membrane synaptic vesicle exocytosis synaptic vesicle exocytosis synaptic vesicle exocytosis vesicle-mediated transport protein sumoylation myosin binding calcium-ion regulated exocytosis regulation of exocytosis calcium channel inhibitor activity chloride channel inhibitor activity kinase binding insulin secretion secretory granule axon synaptic vesicle membrane synaptic vesicle membrane protein-macromolecule adaptor activity SNARE complex SNARE complex cytoplasmic vesicle synaptic vesicle fusion to presynaptic active zone membrane synaptic vesicle fusion to presynaptic active zone membrane nuclear membrane myosin head/neck binding secretion by cell protein-containing complex positive regulation of catecholamine secretion SNARE complex assembly actomyosin presynaptic membrane identical protein binding neuron projection neuron projection ATP-dependent protein binding transmembrane transporter binding protein-containing complex binding regulated exocytosis synapse positive regulation of exocytosis positive regulation of calcium ion-dependent exocytosis hormone secretion vesicle docking vesicle docking calcium-dependent protein binding synaptic vesicle endocytosis presynaptic active zone membrane presynaptic active zone membrane synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex synaptobrevin 2-SNAP-25-syntaxin-1a complex synaptobrevin 2-SNAP-25-syntaxin-1a complex protein localization to membrane Schaffer collateral - CA1 synapse presynapse modulation of excitatory postsynaptic potential postsynaptic density membrane glutamatergic synapse positive regulation of excitatory postsynaptic potential	04130
1456479_at	Snx30	sorting nexin family member 30	4	59805649	BB359719	209131	16	phagophore assembly site autophagy of mitochondrion cytoplasm endosome early endosome early endosome protein transport protein transport membrane endocytic recycling piecemeal microautophagy of the nucleus phosphatidylinositol binding reticulophagy positive regulation of autophagosome assembly
1439825_at	Dtx3l	deltex 3-like, E3 ubiquitin ligase	16	-35926514	BB705351	209200	19	DNA damage checkpoint signaling positive regulation of defense response to virus by host immune system process ubiquitin-protein transferase activity enzyme inhibitor activity nucleus nucleoplasm cytoplasm lysosome endosome early endosome cytosol DNA repair double-strand break repair chromatin organization ubiquitin-dependent protein catabolic process DNA damage response Notch signaling pathway endosome to lysosome transport protein transport membrane protein ubiquitination transferase activity enzyme binding positive regulation of protein binding protein-containing complex positive regulation of chromatin binding histone binding ubiquitin-like protein ligase binding innate immune response positive regulation of DNA-templated transcription metal ion binding negative regulation of ubiquitin-protein transferase activity defense response to virus protein autoubiquitination protein K48-linked ubiquitination STAT family protein binding protein ADP-ribosyltransferase-substrate adaptor activity histone ubiquitin ligase activity DNA repair-dependent chromatin remodeling histone H4K91 ubiquitin ligase activity positive regulation of protein localization to nucleus positive regulation of protein localization to early endosome positive regulation of receptor catabolic process	04330
1435665_at	Trim30d	tripartite motif-containing 30D	7	-104470013	BM241342	209387	13	protein polyubiquitination P-body activation of innate immune response transcription coactivator activity ubiquitin-protein transferase activity nucleoplasm cytoplasm cytoplasm cytosol autophagy positive regulation of autophagy protein kinase binding protein kinase binding protein-macromolecule adaptor activity regulation of lipopolysaccharide-mediated signaling pathway regulation of protein localization regulation of protein localization pattern recognition receptor activity identical protein binding protein homodimerization activity protein homodimerization activity positive regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of MAPK cascade suppression of viral release by host innate immune response innate immune response regulation of viral entry into host cell negative regulation of viral entry into host cell positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity ubiquitin protein ligase activity protein K63-linked ubiquitination omegasome
1423543_at	Swap70	SWA-70 protein	7	110221702	AK019882	20947	65	DNA binding protein binding ATP binding nucleus nucleus cytoplasm cytoplasm cytoskeleton plasma membrane positive regulation of cytosolic calcium ion concentration regulation of actin polymerization or depolymerization actin cytoskeleton membrane somatic cell DNA recombination negative regulation of actin filament depolymerization positive regulation of actin filament bundle assembly regulation of protein localization negative regulation of cell-cell adhesion mediated by integrin cell projection isotype switching actin filament bundle assembly positive regulation of mast cell chemotaxis negative regulation of peptidyl-serine dephosphorylation
1424356_a_at	Metrnl	meteorin, glial cell differentiation regulator-like	11	121702426	BC024445	210029	41	hormone activity hormone activity extracellular region extracellular space extracellular space extracellular space response to cold response to muscle activity fat cell differentiation negative regulation of inflammatory response brown fat cell differentiation positive regulation of brown fat cell differentiation positive regulation of brown fat cell differentiation energy homeostasis energy homeostasis
1435343_at	Dock10	dedicator of cytokinesis 10	1	-80501067, -80501067	BF715043	210293	32	B cell homeostasis marginal zone B cell differentiation guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity nucleus nucleoplasm cytoplasm cytosol small GTPase-mediated signal transduction regulation of cell migration regulation of cell migration small GTPase binding cell projection dendritic spine positive regulation of GTPase activity positive regulation of GTPase activity synapse dendritic spine morphogenesis dendritic spine morphogenesis postsynapse postsynapse glutamatergic synapse glutamatergic synapse
1436423_at	Themis	thymocyte selection associated	10	28668359, 28668359, 28668394	BE628523	210757	42	adaptive immune response immune system process protein binding nucleus nucleus cytoplasm cytoplasm cell-cell junction multicellular organism development COP9 signalosome positive T cell selection negative T cell selection T cell receptor signaling pathway T cell receptor signaling pathway
1435545_at	Bicral	BRD4 interacting chromatin remodeling complex associated protein like	17	-46798115	BB242234	210982	21	chromatin chromatin remodeling regulation of transcription by RNA polymerase II positive regulation of cell population proliferation SWI/SNF complex SWI/SNF complex SWI/SNF complex negative regulation of cell differentiation positive regulation of DNA-templated transcription GBAF complex positive regulation of stem cell population maintenance
1442135_at	Ado	2-aminoethanethiol dioxygenase	10	-67544510	AA839814	211488	20	iron ion binding iron ion binding iron ion binding protein binding mitochondrion oxidoreductase activity oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen metal ion binding cysteamine dioxygenase activity cysteamine dioxygenase activity dioxygenase activity cellular response to hypoxia	00430 01100
1437253_at	Dennd6a	DENN domain containing 6A	14	26573857, 26579549, 26579549	BB235551	211922	18	guanyl-nucleotide exchange factor activity cytoplasm endosome intracellular membrane-bounded organelle recycling endosome recycling endosome positive regulation of cell-cell adhesion mediated by cadherin
1451234_at	Fam193b	family with sequence similarity 193, member B	13	-55539315	BC021381	212483	18	molecular_function nucleus nucleus nucleoplasm nucleolus cytoplasm cytoplasm cytoplasm biological_process nuclear speck
1436397_at	Tifab	TRAF-interacting protein with forkhead-associated domain, family member B	13	-56173702	BB040051	212937	14	toll-like receptor signaling pathway hematopoietic progenitor cell differentiation canonical NF-kappaB signal transduction thorax and anterior abdomen determination regulation of gene expression trigeminal nerve development vestibulocochlear nerve formation myeloid cell differentiation myeloid cell differentiation peristalsis auditory behavior lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway genitalia morphogenesis deubiquitinase activator activity inner ear morphogenesis regulation of muscle organ development genitalia development inner ear development neuromuscular process controlling balance mastication cochlea development cochlea morphogenesis craniofacial suture morphogenesis learned vocalization behavior negative regulation of relaxation of muscle regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator negative regulation of saliva secretion hard palate morphogenesis
1440865_at	Ifitm6	interferon induced transmembrane protein 6	7	-141015811	BB193024	213002	19	molecular_function plasma membrane response to type II interferon response to interferon-alpha response to interferon-beta negative regulation of viral genome replication negative regulation of viral entry into host cell defense response to virus type I interferon-mediated signaling pathway
1455110_at	Gabpb2	GA repeat binding protein, beta 2	3	-95181765	AW536205	213054	28	transcription cis-regulatory region binding transcription cis-regulatory region binding nucleus nucleus identical protein binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II
1447792_x_at	Gpr174	G protein-coupled receptor 174	X	107255877, 107284345	BB241847	213439	22	G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane centriolar satellite positive regulation of Rho protein signal transduction T cell homeostasis intracellular membrane-bounded organelle bioactive lipid receptor activity
1455042_at	Tbl1x	transducin (beta)-like 1 X-linked	X	77511226	BF682509	21372	41	histone deacetylase complex histone deacetylase complex transcription cis-regulatory region binding transcription cis-regulatory region binding DNA binding chromatin binding transcription corepressor activity transcription corepressor activity transcription corepressor activity protein binding nucleus nucleoplasm nucleoplasm transcription regulator complex regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription repressor complex histone binding identical protein binding proteasome-mediated ubiquitin-dependent protein catabolic process response to estrogen fat cell differentiation negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II response to steroid hormone protein stabilization mitotic spindle	04310
1427670_a_at	Tcf12	transcription factor 12	9	-71844251, -71844251, -71844251	M97636	21406	137	chromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleoplasm transcription regulator complex transcription regulator complex cytoplasm regulation of transcription by RNA polymerase II multicellular organism development nervous system development gene expression positive regulation of gene expression nuclear speck cell differentiation cAMP response element binding intracellular membrane-bounded organelle bHLH transcription factor binding positive regulation of neuron differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II SMAD binding protein heterodimerization activity protein dimerization activity E-box binding HMG box domain binding RNA polymerase II transcription regulator complex response to gonadotropin-releasing hormone DNA-binding transcription factor binding sequence-specific double-stranded DNA binding
1434148_at	Tcf4	transcription factor 4	18	69345720, 69344491, 69346159	BB364520	21413	241	negative regulation of transcription by RNA polymerase II chromatin RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific TFIIB-class transcription factor binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA binding chromatin binding double-stranded DNA binding DNA-binding transcription factor activity transcription corepressor activity protein binding nucleus nucleus transcription regulator complex transcription regulator complex regulation of DNA-templated transcription regulation of transcription by RNA polymerase II multicellular organism development nervous system development beta-catenin binding negative regulation of gene expression negative regulation of angiogenesis cell differentiation endothelial cell activation identical protein binding bHLH transcription factor binding protein self-association positive regulation of neuron differentiation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein heterodimerization activity protein dimerization activity protein-DNA complex assembly beta-catenin-TCF7L2 complex E-box binding regulation of vascular endothelial growth factor signaling pathway sequence-specific double-stranded DNA binding beta-catenin-TCF complex
1433471_at	Tcf7	transcription factor 7, T cell specific	11	-52252282, -52252282	AI323642	21414	282	negative regulation of transcription by RNA polymerase II euchromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II beta-catenin binding Wnt signaling pathway nuclear body neural tube development embryonic genitalia morphogenesis T cell receptor V(D)J recombination regulation of cell population proliferation gamma-delta T cell differentiation negative regulation of apoptotic process canonical Wnt signaling pathway involved in negative regulation of apoptotic process regulation of gamma-delta T cell differentiation alpha-beta T cell differentiation embryonic digestive tract morphogenesis embryonic hindgut morphogenesis canonical Wnt signaling pathway canonical Wnt signaling pathway cellular response to interleukin-4 sequence-specific double-stranded DNA binding beta-catenin-TCF complex	04310 04520 04916 05200 05210 05213 05215 05216 05217 05221 05412
1429428_at	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	19	55741809, 55895320	BB175494	21416	286	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development intracellular glucose homeostasis in utero embryonic development DNA binding chromatin binding chromatin binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex cytosol glycogen metabolic process glucose metabolic process regulation of gluconeogenesis regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II beta-catenin binding beta-catenin binding beta-catenin binding fibroblast growth factor receptor signaling pathway cellular response to starvation response to glucose post-embryonic development positive regulation of epithelial to mesenchymal transition positive regulation of triglyceride biosynthetic process positive regulation of heparan sulfate proteoglycan biosynthetic process oligodendrocyte development Wnt signaling pathway nuclear receptor binding protein kinase binding neural tube development pituitary gland development bone mineralization BMP signaling pathway negative regulation of BMP signaling pathway embryonic genitalia morphogenesis regulation of myelination positive regulation of insulin secretion positive regulation of insulin secretion positive regulation of protein binding secretory granule localization regulation of hormone metabolic process protein-DNA complex somatic stem cell population maintenance somatic stem cell population maintenance multicellular organism growth organ growth negative regulation of fibroblast growth factor receptor signaling pathway odontogenesis of dentin-containing tooth glucose homeostasis glucose homeostasis positive regulation of apoptotic process negative regulation of DNA-binding transcription factor activity sequence-specific DNA binding sequence-specific DNA binding maintenance of DNA repeat elements skin development gamma-catenin binding fat cell differentiation negative regulation of fat cell differentiation negative regulation of gluconeogenesis positive regulation of gluconeogenesis negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of organ growth positive regulation of lipid biosynthetic process embryonic digestive tract morphogenesis embryonic hindgut morphogenesis myoblast fate commitment myoblast fate commitment regulation of skeletal muscle tissue development regulation of smooth muscle cell proliferation regulation of oligodendrocyte differentiation epithelial cell proliferation positive regulation of epithelial cell proliferation positive regulation of epithelial cell proliferation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway canonical Wnt signaling pathway face morphogenesis regulation of insulin secretion involved in cellular response to glucose stimulus regulation of insulin secretion involved in cellular response to glucose stimulus RNA polymerase II-specific DNA-binding transcription factor binding armadillo repeat domain binding beta-catenin-TCF7L2 complex catenin-TCF7L2 complex catenin-TCF7L2 complex negative regulation of canonical Wnt signaling pathway positive regulation of protein localization to nucleus insulin metabolic process promoter-specific chromatin binding beta-catenin-TCF complex negative regulation of type B pancreatic cell apoptotic process negative regulation of extrinsic apoptotic signaling pathway	04310 04520 04916 05200 05210 05213 05215 05216 05217 05221 05412
1452377_at	Kmt2a	lysine (K)-specific methyltransferase 2A	9	-44803354	AK017541	214162	226	DNA binding chromatin binding protein binding nucleus nucleus nucleoplasm cytosol DNA methylation chromatin organization regulation of DNA-templated transcription methyltransferase activity zinc ion binding visual learning response to light stimulus post-embryonic development anterior/posterior pattern specification anterior/posterior pattern specification regulation of gene expression positive regulation of gene expression transferase activity peptidyl-lysine monomethylation methylation circadian regulation of gene expression histone methyltransferase complex histone methyltransferase complex embryonic hemopoiesis exploration behavior protein modification process histone H3K4 methyltransferase activity histone H3K4 methyltransferase activity histone H3K4 methyltransferase activity histone H3K4 methyltransferase activity identical protein binding protein homodimerization activity T-helper 2 cell differentiation unmethylated CpG binding transcription initiation-coupled chromatin remodeling positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding fibroblast proliferation negative regulation of fibroblast proliferation regulation of short-term neuronal synaptic plasticity rhythmic process spleen development homeostasis of number of cells within a tissue cognition definitive hemopoiesis protein-containing complex assembly lysine-acetylated histone binding MLL1 complex cellular response to transforming growth factor beta stimulus negative regulation of DNA methylation-dependent heterochromatin formation protein-cysteine methyltransferase activity DNA-binding transcription factor binding histone H3K4 monomethyltransferase activity histone H3K4 trimethyltransferase activity
1426297_at	Tcf3	transcription factor 3	10	-80409540	AF352579	21423	346	negative regulation of transcription by RNA polymerase II chromatin nucleosome euchromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific natural killer cell differentiation B cell lineage commitment DNA binding chromatin binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex transcription regulator complex transcription regulator complex transcription regulator complex cytoplasm cytosol chromatin remodeling regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II gastrulation nervous system development response to xenobiotic stimulus gene expression positive regulation of gene expression positive regulation of gene expression lymphocyte differentiation cell differentiation PDZ domain binding erythrocyte differentiation positive regulation of B cell proliferation mitogen-activated protein kinase kinase kinase binding response to lipopolysaccharide protein-containing complex T cell differentiation in thymus immunoglobulin V(D)J recombination immunoglobulin V(D)J recombination immunoglobulin V(D)J recombination identical protein binding protein homodimerization activity bHLH transcription factor binding bHLH transcription factor binding sequence-specific DNA binding sequence-specific DNA binding positive regulation of neuron differentiation positive regulation of cell cycle positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein heterodimerization activity protein heterodimerization activity protein dimerization activity cell development Peyer's patch development protein stabilization positive regulation of DNA-binding transcription factor activity RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase II-specific DNA-binding transcription factor binding vitamin D response element binding E-box binding E-box binding E-box binding RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex DNA-binding transcription factor binding regulation of G1/S transition of mitotic cell cycle
1419537_at	Tfec	transcription factor EC	6	-16833380	NM_031198	21426	34	negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding nucleus nucleus nucleoplasm cytosol regulation of DNA-templated transcription regulation of transcription by RNA polymerase II cellular response to heat positive regulation of transcription by RNA polymerase II protein dimerization activity sequence-specific double-stranded DNA binding
1434339_at	Fnbp1l	formin binding protein 1-like	3	-122538718	AW548221	214459	30	cytoplasm cytosol cytoskeleton plasma membrane endocytosis vesicle budding from membrane autophagy signal transduction lipid binding membrane invagination membrane vesicle organization vesicle transport along actin filament cytoplasmic vesicle GTPase binding positive regulation of filopodium assembly cilium assembly clathrin-dependent endocytosis plasma membrane tubulation
1457825_x_at	Tcn2	transcobalamin 2	11	-3917079, -3917077, -3917079	BB515151	21452	40	extracellular region extracellular space extracellular space extracellular space extracellular space monoatomic ion transport cobalt ion transport external side of plasma membrane cobalamin transport cobalamin transport cobalamin transport cobalamin binding cobalamin binding cobalamin binding metal ion binding molecular carrier activity cargo receptor ligand activity cargo receptor ligand activity	04977
1444003_at	Neurl3	neuralized E3 ubiquitin protein ligase 3	1	-36264601	AW610818	214854	18	immune system process cytoplasm early endosome protein ubiquitination transferase activity innate immune response metal ion binding ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin-dependent endocytosis
1437105_at	Kdm5a	lysine demethylase 5A	6	120364098	BM246184	214899	59	negative regulation of transcription by RNA polymerase II chromatin transcription cis-regulatory region binding DNA binding chromatin binding transcription coactivator activity enzyme inhibitor activity protein binding nucleus nucleus nucleus nucleoplasm chromatin organization chromatin remodeling regulation of DNA-templated transcription multicellular organism development zinc ion binding oxidoreductase activity chromatin DNA binding histone H3K4 demethylase activity circadian regulation of gene expression protein-DNA complex histone H3K4me/H3K4me2/H3K4me3 demethylase activity histone H3K4me/H3K4me2/H3K4me3 demethylase activity methylated histone binding histone binding positive regulation of DNA-templated transcription metal ion binding rhythmic process regulation of DNA-binding transcription factor activity dioxygenase activity facultative heterochromatin formation
1452099_at	Utp25	UTP25 small subunit processome component	1	-193104399, -193104402, -193104402, -193115655	BG070043	215193	24	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) nucleus nucleolus nucleolus rRNA processing multicellular organism development rRNA binding protein catabolic process protein destabilization small-subunit processome U3 snoRNA binding U3 snoRNA binding positive regulation of embryonic development embryonic organ development protein localization to nucleolus
1434573_at	Traf3ip3	TRAF3 interacting protein 3	1	-193175503	BE986588	215243	27	Golgi membrane cytoplasmic pattern recognition receptor signaling pathway mitochondrion mitochondrial outer membrane lysosome endoplasmic reticulum membrane Golgi apparatus plasma membrane membrane mitochondrial membrane positive regulation of type I interferon production positive regulation of interferon-alpha production positive regulation of interferon-beta production cellular response to interferon-alpha cellular response to interferon-beta regulation of protein homodimerization activity zf-TRAF domain binding molecular adaptor activity antiviral innate immune response
1425958_at	Il36g	interleukin 36G	2	24186475	AY071843	215257	46	cytokine production positive regulation of cytokine production immune system process inflammatory response to antigenic stimulus cytokine activity cytokine activity extracellular region extracellular space extracellular space nucleoplasm cytoplasm cytosol plasma membrane inflammatory response immune response positive regulation of gene expression cytokine-mediated signaling pathway interleukin-6 production positive regulation of interleukin-6 production innate immune response negative regulation of myoblast differentiation cellular response to lipopolysaccharide negative regulation of myoblast fusion
1451243_at	Rnpep	arginyl aminopeptidase (aminopeptidase B)	1	-135262698	BC019200	215615	22	aminopeptidase activity copper ion binding extracellular region extracellular space extracellular space plasma membrane proteolysis proteolysis peptidase activity metallopeptidase activity zinc ion binding external side of plasma membrane protein processing hydrolase activity secretory granule peptide binding negative regulation of blood pressure metal ion binding cobalt ion binding metalloaminopeptidase activity metalloaminopeptidase activity
1434404_at	Miga1	mitoguardin 1	3	-152273459	BB375245	215708	23	mitochondrion mitochondrial outer membrane plasma membrane mitochondrial fusion mitochondrial fusion mitochondrial fusion membrane protein homodimerization activity protein heterodimerization activity
1426159_x_at	Tcrb-J	T cell receptor beta, joining region	6		U46841	21580	50
1454658_at	Ilvbl	ilvB (bacterial acetolactate synthase)-like	10	78574512, 78574499, 78574990, 78574990	BI408416	216136	19	magnesium ion binding fatty acid alpha-oxidation catalytic activity acetolactate synthase activity endoplasmic reticulum endoplasmic reticulum membrane acetolactate synthase complex lipid metabolic process fatty acid metabolic process isoleucine biosynthetic process valine biosynthetic process membrane lyase activity thiamine pyrophosphate binding metal ion binding flavin adenine dinucleotide binding
1437377_a_at	Polrmt	polymerase (RNA) mitochondrial (DNA directed)	10	-79736124	BB739221	216151	29	3'-5'-RNA exonuclease activity DNA-directed RNA polymerase complex mitochondrial promoter sequence-specific DNA binding DNA binding DNA primase activity DNA-directed 5'-3' RNA polymerase activity DNA-directed 5'-3' RNA polymerase activity protein binding mitochondrion mitochondrion mitochondrial matrix DNA-templated transcription mitochondrial transcription mitochondrial transcription transcription initiation at mitochondrial promoter transferase activity nucleotidyltransferase activity protein-containing complex protein-containing complex mitochondrial DNA-directed RNA polymerase complex mitochondrial nucleoid sequence-specific DNA binding sequence-specific DNA binding
1455019_x_at	Ckap4	cytoskeleton-associated protein 4	10	-84526304	BB818012	216197	39	molecular_function protein binding cytoplasm endoplasmic reticulum endoplasmic reticulum rough endoplasmic reticulum rough endoplasmic reticulum lipid droplet cytoskeleton plasma membrane biological_process cell surface membrane	04141
1434306_at	Rab3ip	RAB3A interacting protein	10	-116905779	BF319015	216363	30	guanyl-nucleotide exchange factor activity protein binding nucleus cytoplasm centrosome cytosol cytoskeleton protein targeting to membrane exocytosis protein transport small GTPase binding small GTPase binding protein localization to organelle identical protein binding identical protein binding cell projection perinuclear region of cytoplasm GTPase binding negative regulation of filopodium assembly cilium assembly Golgi to plasma membrane transport vesicle proximal dendrite
1428332_at	Pik3ip1	phosphoinositide-3-kinase interacting protein 1	11	3330730	AW556858	216505	28	endopeptidase activity signaling receptor binding extracellular space plasma membrane membrane negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction phosphatidylinositol 3-kinase inhibitor activity phosphatidylinositol 3-kinase inhibitor activity
1416542_at	Phf1	PHD finger protein 1	17	26933126	NM_009343	21652	36	transcription corepressor binding DNA binding chromatin binding chromatin binding protein binding nucleus nucleus nucleoplasm cytoplasm centrosome cytosol cytoskeleton chromatin organization chromatin organization regulation of DNA-templated transcription DNA damage response methylated histone binding methylated histone binding methylated histone binding ESC/E(Z) complex ESC/E(Z) complex site of double-strand break identical protein binding metal ion binding DNA repair-dependent chromatin remodeling histone methyltransferase binding
1434648_a_at	Ccm2	cerebral cavernous malformation 2	11	6560182, 6546886	BI903794	216527	60	blood vessel development vasculogenesis vasculogenesis vasculogenesis in utero embryonic development in utero embryonic development endothelial cell development endothelial cell development vasculature development vasculature development endothelium development protein binding cytoplasm mitochondrion heart development heart development heart development heart development protein-containing complex multicellular organism growth multicellular organism growth cell-cell junction organization regulation of angiogenesis inner ear development venous blood vessel morphogenesis venous blood vessel morphogenesis pericardium development pericardium development blood vessel endothelial cell differentiation endothelial tube morphogenesis
1436034_at	Cep68	centrosomal protein 68	11	-20227036	AW550283	216543	20	nucleoplasm cytoplasm centrosome cytosol cytoskeleton centrosome cycle centriole-centriole cohesion protein kinase binding protein domain specific binding cell junction protein localization to organelle centriolar satellite
1427241_at	Papolg	poly(A) polymerase gamma	11	-23862645	BC019635	216578	16	nucleotide binding RNA binding ATP binding nucleus nucleus nucleoplasm cytosol mRNA polyadenylation mRNA processing nuclear body transferase activity nucleotidyltransferase activity RNA 3'-end processing metal ion binding poly(A) RNA polymerase activity	03015
1460204_at	Tec	tec protein tyrosine kinase	5	-72755717	NM_013689	21682	76	nucleotide binding adaptive immune response adaptive immune response immune system process protein kinase activity protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding cytoplasm cytosol cytoskeleton plasma membrane plasma membrane cell-cell junction protein phosphorylation protein phosphorylation integrin-mediated signaling pathway lipid binding regulation of platelet activation regulation of platelet activation membrane kinase activity phosphorylation transferase activity intracellular signal transduction tissue regeneration protein self-association metal ion binding T cell receptor signaling pathway B cell receptor signaling pathway B cell receptor signaling pathway	04380 04660
1428466_at	Chd3	chromodomain helicase DNA binding protein 3	11	-69343272	AK011183	216848	37	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin transcription cis-regulatory region binding DNA binding chromatin binding protein binding nucleus nucleus nucleoplasm nucleoplasm nucleolus cytoplasm centrosome chromatin organization chromatin remodeling chromatin remodeling spindle organization centrosome cycle NuRD complex NuRD complex NuRD complex NuRD complex PML body ATP hydrolysis activity ATP hydrolysis activity centriolar satellite histone binding regulation of cell fate specification negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription ATP-dependent chromatin remodeler activity ATP-dependent chromatin remodeler activity regulation of stem cell differentiation
1434873_a_at	Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	11	-69881566	BB115902	216859	18	molecular_function GTPase activator activity cytoplasm endosome lipid metabolic process signal transduction biological_process membrane lipid catabolic process metal ion binding	04144
1451601_a_at	Spns2	SPNS lysolipid transporter 2, sphingosine-1-phosphate	11	-72451637, -72451637	BC025823	216892	43	B cell homeostasis lymphocyte homeostasis regulation of humoral immune response regulation of humoral immune response sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway sphingosine-1-phosphate receptor signaling pathway endosome plasma membrane sphingolipid metabolic process lipid transport lipid transport sensory perception of sound membrane membrane transmembrane transporter activity T cell homeostasis sphingolipid transporter activity sphingolipid transporter activity sphingolipid transporter activity regulation of eye pigmentation lymph node development transmembrane transport bone development lymphocyte migration regulation of T cell migration
1425025_at	Tmem106a	transmembrane protein 106A	11	101582241, 101582241, 101582298	BC022145	217203	14	immune system process molecular_function plasma membrane membrane positive regulation of interleukin-1 beta production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production CD80 biosynthetic process CD86 biosynthetic process macrophage activation positive regulation of canonical NF-kappaB signal transduction positive regulation of MAPK cascade innate immune response positive regulation of MHC class II biosynthetic process positive regulation of nitric oxide metabolic process
1460363_at	Tnrc6c	trinucleotide repeat containing 6C	11	117654288	BB795102	217351	25	P-body endoderm formation molecular_function nucleic acid binding RNA binding nucleoplasm cytosol regulation of translation transforming growth factor beta receptor signaling pathway endoderm development regulatory ncRNA-mediated gene silencing embryonic hemopoiesis miRNA-mediated post-transcriptional gene silencing miRNA-mediated post-transcriptional gene silencing embryonic organ development positive regulation of nuclear-transcribed mRNA poly(A) tail shortening positive regulation of nuclear-transcribed mRNA poly(A) tail shortening lung saccule development regulation of miRNA-mediated gene silencing positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
1426640_s_at	Trib2	tribbles pseudokinase 2	12	-15791726	BB354684	217410	56	protein kinase activity protein kinase inhibitor activity ATP binding nucleus cytoplasm cytoskeleton protein phosphorylation mitogen-activated protein kinase kinase binding ubiquitin protein ligase binding positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of interleukin-10 production regulation of MAP kinase activity negative regulation of DNA-binding transcription factor activity negative regulation of fat cell differentiation positive regulation of ubiquitin-protein transferase activity ubiquitin-protein transferase regulator activity RNA polymerase II-specific DNA-binding transcription factor binding
1448224_at	Tfam	transcription factor A, mitochondrial	10	-71225476	NM_009360	21780	225	transcription cis-regulatory region binding mitochondrial promoter sequence-specific DNA binding mitochondrial promoter sequence-specific DNA binding transcription coactivator binding DNA binding chromatin binding nucleus mitochondrion mitochondrion mitochondrion mitochondrial matrix mitochondrial transcription mitochondrial transcription transcription initiation at mitochondrial promoter transcription initiation at mitochondrial promoter heat shock protein binding protein-containing complex mitochondrial respiratory chain complex assembly mitochondrial transcription factor activity mitochondrial nucleoid mitochondrial nucleoid sequence-specific DNA binding positive regulation of DNA-templated transcription	05016
1415871_at	Tgfbi	transforming growth factor, beta induced	13	56609585	NM_009369	21810	91	extracellular matrix structural constituent collagen binding extracellular region basement membrane extracellular space extracellular space extracellular space extracellular space trans-Golgi network cell adhesion cell adhesion extracellular matrix organization extracellular matrix organization extracellular matrix extracellular matrix identical protein binding cell adhesion molecule binding extracellular matrix binding localization collagen-containing extracellular matrix
1426397_at	Tgfbr2	transforming growth factor, beta receptor II	9	-116087694	BG793483	21813	626	nucleotide binding branching involved in blood vessel morphogenesis vasculogenesis in utero embryonic development epithelial to mesenchymal transition heart looping positive regulation of mesenchymal cell proliferation lens development in camera-type eye positive regulation of tolerance induction to self antigen positive regulation of B cell tolerance induction positive regulation of T cell tolerance induction outflow tract septum morphogenesis membranous septum morphogenesis outflow tract morphogenesis aortic valve morphogenesis atrioventricular valve morphogenesis tricuspid valve morphogenesis cardiac left ventricle morphogenesis endocardial cushion fusion growth plate cartilage development growth plate cartilage chondrocyte growth protein kinase activity protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase activity transforming growth factor beta receptor activity transforming growth factor beta receptor activity transforming growth factor beta receptor activity transforming growth factor beta receptor activity, type II protein binding ATP binding glycosaminoglycan binding extracellular space plasma membrane plasma membrane plasma membrane caveola protein phosphorylation protein phosphorylation receptor-mediated endocytosis apoptotic process transmembrane receptor protein serine/threonine kinase signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway Notch signaling pathway smoothened signaling pathway gastrulation brain development heart development heart development negative regulation of cell population proliferation response to xenobiotic stimulus animal organ morphogenesis external side of plasma membrane external side of plasma membrane cell surface regulation of gene expression positive regulation of epithelial cell migration positive regulation of epithelial to mesenchymal transition membrane kinase activity phosphorylation transferase activity activin receptor activity kinase activator activity cell differentiation lung development mitogen-activated protein kinase kinase kinase binding type I transforming growth factor beta receptor binding type I transforming growth factor beta receptor binding type III transforming growth factor beta receptor binding embryonic hemopoiesis aorta morphogenesis signaling receptor activity regulation of cell population proliferation receptor complex receptor complex membrane raft positive regulation of angiogenesis SMAD binding SMAD binding SMAD binding metal ion binding activin binding positive regulation of smooth muscle cell proliferation embryonic cranial skeleton morphogenesis artery morphogenesis transforming growth factor beta binding transforming growth factor beta binding transforming growth factor beta binding positive regulation of NK T cell differentiation cartilage development roof of mouth development negative regulation of cardiac muscle cell proliferation molecular adaptor activity positive regulation of SMAD protein signal transduction SMAD protein signal transduction ventricular septum morphogenesis lung morphogenesis bronchus development bronchus morphogenesis trachea morphogenesis trachea formation mammary gland morphogenesis lung lobe morphogenesis Langerhans cell differentiation secondary palate development transforming growth factor beta ligand-receptor complex response to cholesterol response to cholesterol cellular response to growth factor stimulus regulation of stem cell proliferation positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation inferior endocardial cushion morphogenesis lens fiber cell apoptotic process miRNA transport positive regulation of reactive oxygen species metabolic process positive regulation of CD4-positive, alpha-beta T cell proliferation regulation of stem cell differentiation	04010 04060 04144 04350 04380 04520 05142 05200 05210 05212 05220
1433795_at	Tgfbr3	transforming growth factor, beta receptor III	5	-107106566	BM122301	21814	93	blood vessel development vasculogenesis osteoblast differentiation in utero embryonic development blastocyst development epithelial to mesenchymal transition epithelial to mesenchymal transition liver development blood vessel remodeling muscular septum morphogenesis outflow tract morphogenesis ventricular compact myocardium morphogenesis epicardial cell to mesenchymal cell transition transmembrane signaling receptor activity transforming growth factor beta receptor activity transforming growth factor beta receptor activity transforming growth factor beta receptor activity transforming growth factor beta receptor activity type II transforming growth factor beta receptor binding type II transforming growth factor beta receptor binding transforming growth factor beta receptor binding protein binding glycosaminoglycan binding glycosaminoglycan binding extracellular region extracellular space cytoplasm endoplasmic reticulum plasma membrane immune response transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor signaling pathway transforming growth factor beta receptor complex assembly heparin binding cell population proliferation positive regulation of cell population proliferation external side of plasma membrane cell surface positive regulation of gene expression negative regulation of gene expression negative regulation of epithelial cell migration negative regulation of epithelial to mesenchymal transition coreceptor activity membrane cell migration regulation of transforming growth factor beta receptor signaling pathway fibroblast growth factor binding PDZ domain binding negative regulation of cell migration BMP signaling pathway BMP signaling pathway positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of transforming growth factor beta receptor signaling pathway negative regulation of transforming growth factor beta receptor signaling pathway positive regulation of BMP signaling pathway response to follicle-stimulating hormone collagen metabolic process inhibin-betaglycan-ActRII complex response to prostaglandin E response to luteinizing hormone intracellular signal transduction BMP binding negative regulation of canonical NF-kappaB signal transduction receptor complex SMAD binding SMAD binding activin binding transforming growth factor beta binding transforming growth factor beta binding transforming growth factor beta binding negative regulation of epithelial cell proliferation positive regulation of NF-kappaB transcription factor activity ventricular cardiac muscle tissue morphogenesis roof of mouth development cardiac muscle cell proliferation positive regulation of cardiac muscle cell proliferation definitive hemopoiesis cardiac epithelial to mesenchymal transition definitive erythrocyte differentiation heart trabecula formation positive regulation of SMAD protein signal transduction positive regulation of SMAD protein signal transduction negative regulation of SMAD protein signal transduction ventricular septum morphogenesis apoptotic process involved in morphogenesis epicardium-derived cardiac fibroblast cell development coronary vasculature development coronary vasculature morphogenesis vasculogenesis involved in coronary vascular morphogenesis vasculogenesis involved in coronary vascular morphogenesis visceral serous pericardium development heart trabecula morphogenesis secondary palate development protein-containing complex assembly transforming growth factor beta receptor activity, type III positive regulation of cell migration involved in sprouting angiogenesis blood vessel diameter maintenance negative regulation of extracellular matrix assembly negative regulation of apoptotic process involved in morphogenesis
1451416_a_at	Tgm1	transglutaminase 1, K polypeptide	14	-55700008, -55700008	BC026422	21816	66	protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity adherens junction animal organ morphogenesis positive regulation of keratinocyte proliferation membrane transferase activity acyltransferase activity peptide cross-linking peptide cross-linking protein metabolic process keratinocyte differentiation keratinization identical protein binding positive regulation of cell cycle metal ion binding
1433428_x_at	Tgm2	transglutaminase 2, C polypeptide	2	-158116404	AW321975	21817	290	nucleotide binding chromatin nucleosome blood vessel remodeling protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity protein-glutamine gamma-glutamyltransferase activity calcium ion binding calcium ion binding GTP binding GTP binding extracellular region nucleus chromosome cytoplasm mitochondrion mitochondrion cytosol cytosol plasma membrane proteolysis G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway peptidase activity transaminase activity gene expression dopamine secretion membrane transferase activity acyltransferase activity hydrolase activity peptide cross-linking peptide cross-linking peptide cross-linking protein deamination protein domain specific binding extracellular matrix extracellular matrix negative regulation of endoplasmic reticulum calcium ion concentration negative regulation of endoplasmic reticulum calcium ion concentration identical protein binding regulation of apoptotic process positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction phospholipase binding apoptotic cell clearance positive regulation of cell adhesion metal ion binding perinuclear region of cytoplasm positive regulation of smooth muscle cell proliferation protein-glutamine glutaminase activity positive regulation of neurogenesis protein homooligomerization positive regulation of mitochondrial calcium ion concentration positive regulation of mitochondrial calcium ion concentration branching involved in salivary gland morphogenesis salivary gland cavitation collagen-containing extracellular matrix cellular response to cocaine histone serotonyltransferase activity histone dopaminyltransferase activity peptide histaminyltransferase activity cellular response to dopamine cellular response to serotonin regulation of apoptotic cell clearance regulation of apoptotic cell clearance	05016
1424988_at	Mylip	myosin regulatory light chain interacting protein	13	45389741	BC010206	218203	32	ubiquitin-protein transferase activity ubiquitin-protein transferase activity ubiquitin-protein transferase activity cytoplasm cytoskeleton plasma membrane ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process nervous system development cytoskeletal protein binding negative regulation of neuron projection development negative regulation of low-density lipoprotein particle clearance membrane protein ubiquitination transferase activity protein destabilization regulation of low-density lipoprotein particle receptor catabolic process cholesterol homeostasis positive regulation of protein catabolic process metal ion binding ubiquitin protein ligase activity ubiquitin protein ligase activity cellular response to low-density lipoprotein particle stimulus
1433649_at	Kdm1b	lysine (K)-specific demethylase 1B	13	47043498	BM243793	218214	28	negative regulation of transcription by RNA polymerase II chromatin nucleosome chromatin binding protein binding nucleus nucleoplasm chromosome chromatin organization multicellular organism development transcription factor binding zinc ion binding zinc ion binding oxidoreductase activity oxidoreductase activity histone H3K4 demethylase activity histone binding epigenetic programing of female pronucleus transcription initiation-coupled chromatin remodeling positive regulation of transcription by RNA polymerase II metal ion binding flavin adenine dinucleotide binding flavin adenine dinucleotide binding genomic imprinting FAD binding FAD-dependent H3K4me/H3K4me3 demethylase activity FAD-dependent H3K4me/H3K4me3 demethylase activity
1460302_at	Thbs1	thrombospondin 1	2	118111875	AI385532	21825	363	angiogenesis phosphatidylserine binding negative regulation of endothelial cell proliferation negative regulation of endothelial cell proliferation negative regulation of cell-matrix adhesion fibronectin binding protease binding sprouting angiogenesis negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II negative regulation of dendritic cell antigen processing and presentation outflow tract morphogenesis endocardial cushion development growth plate cartilage development growth plate cartilage development endopeptidase inhibitor activity integrin binding extracellular matrix structural constituent calcium ion binding protein binding extracellular region fibrinogen complex extracellular space extracellular space extracellular space endoplasmic reticulum apoptotic process inflammatory response inflammatory response response to unfolded protein cell adhesion heparin binding positive regulation of cell population proliferation negative regulation of cell population proliferation response to mechanical stimulus response to glucose external side of plasma membrane cell surface positive regulation of endothelial cell migration negative regulation of endothelial cell migration negative regulation of long-chain fatty acid import across plasma membrane negative regulation of nitric oxide mediated signal transduction negative regulation of cGMP-mediated signaling negative regulation of plasminogen activation positive regulation of macrophage chemotaxis positive regulation of fibroblast migration positive regulation of cell-substrate adhesion cell migration negative regulation of angiogenesis negative regulation of angiogenesis negative regulation of angiogenesis negative regulation of angiogenesis sarcoplasmic reticulum fibroblast growth factor binding peptide cross-linking secretory granule low-density lipoprotein particle binding positive regulation of blood coagulation positive regulation of cell migration positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of transforming growth factor beta receptor signaling pathway extracellular matrix platelet alpha granule response to magnesium ion negative regulation of interleukin-12 production positive regulation of tumor necrosis factor production response to endoplasmic reticulum stress negative regulation of fibroblast growth factor receptor signaling pathway positive regulation of phosphorylation protein homodimerization activity positive regulation of macrophage activation negative regulation of apoptotic process negative regulation of cysteine-type endopeptidase activity involved in apoptotic process laminin binding positive regulation of MAP kinase activity positive regulation of blood vessel endothelial cell migration negative regulation of blood vessel endothelial cell migration engulfment of apoptotic cell positive regulation of translation positive regulation of angiogenesis behavioral response to pain blood vessel morphogenesis positive regulation of smooth muscle cell proliferation transforming growth factor beta binding extracellular matrix binding positive regulation of chemotaxis response to calcium ion positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of fibrinolysis collagen-containing extracellular matrix collagen-containing extracellular matrix fibrinogen binding collagen V binding monocyte aggregation positive regulation of transforming growth factor beta production cellular response to nitric oxide negative regulation of cell migration involved in sprouting angiogenesis positive regulation of extrinsic apoptotic signaling pathway via death domain receptors negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis negative regulation of sprouting angiogenesis positive regulation of endothelial cell apoptotic process positive regulation of reactive oxygen species metabolic process negative regulation of endothelial cell chemotaxis	04115 04145 04350 04510 04512 05144 05219
1451221_at	Ice1	interactor of little elongation complex ELL subunit 1	13	-70588688	BC018507	218333	19	euchromatin nucleus nucleoplasm transcription elongation factor complex Cajal body nuclear body protein-macromolecule adaptor activity positive regulation of protein-containing complex assembly histone locus body snRNA transcription by RNA polymerase II snRNA transcription by RNA polymerase III positive regulation of transcription by RNA polymerase III positive regulation of intracellular protein transport
1423135_at	Thy1	thymus cell antigen 1, theta	9	44043383	AV028402	21838	303	angiogenesis regulation of cell-matrix adhesion positive regulation of cellular extravasation GTPase activator activity GTPase activator activity integrin binding integrin binding endoplasmic reticulum cytosol plasma membrane cytoskeleton organization integrin-mediated signaling pathway integrin-mediated signaling pathway integrin-mediated signaling pathway cell-cell signaling cell-cell signaling external side of plasma membrane external side of plasma membrane cell surface membrane apical plasma membrane enzyme binding protein kinase binding negative regulation of cell migration dendrite dendrite growth cone axolemma dendrite membrane neuronal cell body membrane heterotypic cell-cell adhesion GPI anchor binding receptor clustering myelin sheath membrane raft membrane raft membrane raft retinal cone cell development focal adhesion assembly negative regulation of axonogenesis T cell receptor signaling pathway negative regulation of T cell receptor signaling pathway positive regulation of T cell activation positive regulation of release of sequestered calcium ion into cytosol positive regulation of focal adhesion assembly positive regulation of focal adhesion assembly positive regulation of focal adhesion assembly negative regulation of neuron projection regeneration negative regulation of neuron projection regeneration side of membrane cell-cell adhesion regulation of Rho-dependent protein serine/threonine kinase activity	04670
1416814_at	Tia1	cytotoxic granule-associated RNA binding protein 1	6	86404218	BG518542	21841	77	regulation of alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome negative regulation of cytokine production nucleic acid binding RNA binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol mRNA processing apoptotic process RNA splicing cytoplasmic stress granule cytoplasmic stress granule negative regulation of translation negative regulation of translation stress granule assembly mRNA 3'-UTR AU-rich region binding regulation of mRNA splicing, via spliceosome nuclear stress granule nuclear stress granule protein localization to cytoplasmic stress granule positive regulation of epithelial cell apoptotic process ribonucleoprotein complex
1452821_at	Tial1	Tia1 cytotoxic granule-associated RNA binding protein-like 1	7	-128439776, -128439776	AK020218	21843	55	nucleic acid binding DNA binding RNA binding mRNA 3'-UTR binding protein binding nucleus nucleoplasm cytoplasm lysosome cytosol apoptotic process germ cell development negative regulation of cell population proliferation cytoplasmic stress granule cytoplasmic stress granule stem cell division positive regulation of hippo signaling mRNA 3'-UTR AU-rich region binding stem cell proliferation protein-RNA adaptor activity ribonucleoprotein complex positive regulation of miRNA-mediated gene silencing positive regulation of stem cell proliferation
1415869_a_at	Trim28	tripartite motif-containing 28	7	13024151	NM_011588	21849	205	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin euchromatin heterochromatin in utero embryonic development epithelial to mesenchymal transition DNA binding DNA binding chromatin binding chromatin binding transcription coactivator activity transcription corepressor activity protein kinase activity ubiquitin-protein transferase activity protein binding nucleus nucleus nucleoplasm nucleoplasm DNA repair chromatin organization chromatin organization protein phosphorylation embryo implantation zinc ion binding transferase activity protein sumoylation protein sumoylation SUMO transferase activity ubiquitin protein ligase binding protein-containing complex Krueppel-associated box domain binding positive regulation of protein import into nucleus post-fertilization epigenetic regulation of gene expression positive regulation of DNA binding positive regulation of DNA binding suppression of viral release by host innate immune response innate immune response innate immune response innate immune response positive regulation of DNA repair negative regulation of single stranded viral RNA replication via double stranded DNA intermediate negative regulation of single stranded viral RNA replication via double stranded DNA intermediate negative regulation of single stranded viral RNA replication via double stranded DNA intermediate negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription protein autophosphorylation metal ion binding convergent extension involved in axis elongation embryonic placenta morphogenesis ubiquitin protein ligase activity chromo shadow domain binding genomic imprinting positive regulation of DNA methylation-dependent heterochromatin formation positive regulation of DNA methylation-dependent heterochromatin formation RNA polymerase II transcription regulator complex RNA polymerase II transcription regulator complex negative regulation of DNA demethylation promoter-specific chromatin binding
1460227_at	Timp1	tissue inhibitor of metalloproteinase 1	X	20870165	BC008107	21857	283	protease binding protease binding connective tissue replacement involved in inflammatory response wound healing enzyme inhibitor activity cytokine activity extracellular region basement membrane basement membrane extracellular space extracellular space extracellular space growth factor activity metalloendopeptidase inhibitor activity metalloendopeptidase inhibitor activity zinc ion binding positive regulation of cell population proliferation response to hormone negative regulation of peptidase activity negative regulation of endopeptidase activity negative regulation of endopeptidase activity peptidase inhibitor activity extracellular matrix extracellular matrix response to cytokine negative regulation of apoptotic process negative regulation of catalytic activity metal ion binding negative regulation of membrane protein ectodomain proteolysis negative regulation of membrane protein ectodomain proteolysis cellular response to UV-A negative regulation of trophoblast cell migration negative regulation of metallopeptidase activity regulation of integrin-mediated signaling pathway
1451253_at	Pxk	PX domain containing serine/threonine kinase	14	8098210	BC016131	218699	24	actin binding protein kinase activity protein binding ATP binding nucleus cytoplasm cytoplasm early endosome late endosome cytosol plasma membrane plasma membrane plasma membrane protein phosphorylation protein targeting to lysosome inflammatory response endosome to lysosome transport membrane negative regulation of ATP-dependent activity negative regulation of ATP-dependent activity protein-containing complex centriolar satellite phosphatidylinositol binding phosphatidylinositol binding negative regulation of monoatomic ion transport negative regulation of monoatomic ion transport early endosome to late endosome transport modulation of chemical synaptic transmission
1438673_at	Slc4a7	solute carrier family 4, sodium bicarbonate cotransporter, member 7	14	14703024, 14718783	AW555750	218756	49	solute:inorganic anion antiporter activity protein binding cytoplasm plasma membrane plasma membrane plasma membrane purine nucleotide biosynthetic process pyrimidine nucleotide biosynthetic process monoatomic ion transport sodium ion transport monoatomic anion transport visual perception sensory perception of sound monoatomic anion transmembrane transporter activity sodium:bicarbonate symporter activity sodium:bicarbonate symporter activity sodium:bicarbonate symporter activity symporter activity bicarbonate transport membrane basolateral plasma membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane apical plasma membrane apical plasma membrane cochlear nucleus development cytoplasmic vesicle stereocilium locomotory exploration behavior cell projection retinal cell programmed cell death regulation of intracellular pH regulation of intracellular pH transmembrane transport auditory receptor cell development auditory receptor cell development camera-type eye photoreceptor cell differentiation retina vasculature morphogenesis in camera-type eye cellular response to growth factor stimulus phagosome acidification
1437525_a_at	Polr3a	polymerase (RNA) III (DNA directed) polypeptide A	14	-24448693	BB559175	218832	19	magnesium ion binding RNA polymerase III activity chromatin binding DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm RNA polymerase III complex RNA polymerase III complex cytoplasm zinc ion binding positive regulation of interferon-beta production tRNA transcription by RNA polymerase III innate immune response DNA/RNA hybrid binding	00230 00240 01100 03020 04623
1418162_at	Tlr4	toll-like receptor 4	4	66827550	AF185285	21898	3343	lipopolysaccharide binding lipopolysaccharide binding microglial cell activation lipopolysaccharide immune receptor activity lipopolysaccharide immune receptor activity lipopolysaccharide immune receptor activity phagocytic cup activation of innate immune response toll-like receptor signaling pathway wound healing involved in inflammatory response B cell proliferation involved in immune response immune system process nitric oxide production involved in inflammatory response regulation of dendritic cell cytokine production MyD88-dependent toll-like receptor signaling pathway MyD88-dependent toll-like receptor signaling pathway MyD88-dependent toll-like receptor signaling pathway innate immune response-activating signaling pathway transmembrane signaling receptor activity signaling receptor binding protein binding cytoplasm endosome plasma membrane plasma membrane leukotriene metabolic process nitric oxide biosynthetic process phagocytosis inflammatory response inflammatory response immune response response to oxidative stress signal transduction activation of NF-kappaB-inducing kinase activity I-kappaB phosphorylation I-kappaB phosphorylation JNK cascade JNK cascade response to bacterium external side of plasma membrane cell surface endosome membrane gene expression positive regulation of platelet activation positive regulation of gene expression positive regulation of gene expression positive regulation of gene expression macrophage cytokine production macrophage cytokine production astrocyte development microglia differentiation positive regulation of smooth muscle cell migration membrane neurogenesis positive regulation of B cell proliferation lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway lipopolysaccharide-mediated signaling pathway response to lipopolysaccharide response to lipopolysaccharide response to lipopolysaccharide detection of lipopolysaccharide detection of lipopolysaccharide detection of lipopolysaccharide detection of lipopolysaccharide interferon-beta production type II interferon production interleukin-10 production interleukin-6 production interleukin-6 production tumor necrosis factor production tumor necrosis factor production regulation of tumor necrosis factor production negative regulation of type II interferon production negative regulation of interleukin-17 production negative regulation of interleukin-23 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of chemokine production positive regulation of chemokine production positive regulation of interferon-alpha production positive regulation of interferon-beta production positive regulation of interferon-beta production positive regulation of type II interferon production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 production positive regulation of interleukin-1 production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-12 production positive regulation of interleukin-13 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway toll-like receptor 4 signaling pathway TRIF-dependent toll-like receptor signaling pathway cellular response to platelet-derived growth factor stimulus signaling receptor activity B cell proliferation macrophage activation macrophage activation macrophage activation defense response to bacterium identical protein binding cell projection positive regulation of macrophage activation positive regulation of apoptotic process positive regulation of canonical NF-kappaB signal transduction receptor complex receptor complex positive regulation of MAP kinase activity phosphatidylinositol 3-kinase binding innate immune response MHC class II biosynthetic process positive regulation of MHC class II biosynthetic process positive regulation of nitric oxide biosynthetic process positive regulation of nitric oxide biosynthetic process response to ethanol mast cell activation positive regulation of transcription by RNA polymerase II positive regulation of JNK cascade positive regulation of JNK cascade lymphocyte proliferation lipopolysaccharide receptor complex protein heterodimerization activity perinuclear region of cytoplasm positive regulation of smooth muscle cell proliferation positive regulation of lymphocyte proliferation regulation of inflammatory response positive regulation of inflammatory response positive regulation of inflammatory response positive regulation of peptidyl-tyrosine phosphorylation defense response to Gram-negative bacterium defense response to Gram-negative bacterium detection of temperature stimulus involved in sensory perception of pain detection of mechanical stimulus involved in sensory perception of pain positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity stress-activated MAPK cascade positive regulation of nitric-oxide synthase biosynthetic process intestinal epithelial structure maintenance positive regulation of macrophage cytokine production positive regulation of macrophage cytokine production positive regulation of macrophage cytokine production ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade nucleotide-binding oligomerization domain containing 1 signaling pathway positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway nucleotide-binding oligomerization domain containing 2 signaling pathway positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway response to fatty acid cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to lipoteichoic acid cellular response to type II interferon negative regulation of cold-induced thermogenesis cellular response to oxidised low-density lipoprotein particle stimulus cellular response to oxidised low-density lipoprotein particle stimulus positive regulation of cytokine production involved in inflammatory response positive regulation of cytokine production involved in inflammatory response positive regulation of NLRP3 inflammasome complex assembly positive regulation of non-canonical NF-kappaB signal transduction positive regulation of reactive oxygen species biosynthetic process positive regulation of cellular response to macrophage colony-stimulating factor stimulus positive regulation of matrix metallopeptidase secretion cellular response to amyloid-beta positive regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of extrinsic apoptotic signaling pathway	04145 04620 05140 05142 05144 05145 05146 05323
1422754_at	Tmod1	tropomodulin 1	4	46039221	NM_021883	21916	65	actin binding tropomyosin binding tropomyosin binding tropomyosin binding cytoplasm cytoskeleton cytoskeleton striated muscle thin filament striated muscle thin filament actin filament muscle contraction muscle contraction actin filament organization COP9 signalosome adult locomotory behavior membrane myofibril myofibril myofibril sarcomere sarcomere myofibril assembly myofibril assembly cortical cytoskeleton pointed-end actin filament capping lens fiber cell development
1438855_x_at	Tnfaip2	tumor necrosis factor, alpha-induced protein 2	12	111442660	BB233088	21928	30	exocyst exocyst SNARE binding angiogenesis exocytosis exocytosis multicellular organism development cell differentiation exocyst localization
1460415_a_at	Cd40	CD40 antigen	2	165055635	AI385482	21939	607	positive regulation of protein phosphorylation immune system process immunoglobulin production regulation of immunoglobulin production immune response-regulating cell surface receptor signaling pathway immune response-regulating cell surface receptor signaling pathway antigen binding protein binding extracellular region extracellular space plasma membrane intracellular calcium ion homeostasis intracellular calcium ion homeostasis external side of plasma membrane external side of plasma membrane cell surface cell surface membrane B cell mediated immunity enzyme binding protein domain specific binding CD40 signaling pathway CD40 signaling pathway positive regulation of B cell proliferation positive regulation of B cell proliferation ubiquitin protein ligase binding interleukin-12 production positive regulation of interleukin-12 production CD40 receptor complex CD40 receptor complex signaling receptor activity B cell proliferation B cell proliferation B cell activation B cell activation B cell activation positive regulation of tyrosine phosphorylation of STAT protein defense response to protozoan neuronal cell body varicosity intracellular membrane-bounded organelle positive regulation of MAP kinase activity phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of blood vessel endothelial cell migration positive regulation of GTPase activity positive regulation of angiogenesis positive regulation of transcription by RNA polymerase II positive regulation of isotype switching to IgG isotypes regulation of immune response positive regulation of NF-kappaB transcription factor activity defense response to virus positive regulation of protein kinase C signaling positive regulation of endothelial cell apoptotic process	04060 04514 04620 04672 05144 05145 05310 05320 05322 05330 05340 05416
1452389_at	Cd27	CD27 antigen	6	-125232621	L24495	21940	112	positive regulation of immunoglobulin production transmembrane signaling receptor activity protein binding apoptotic process external side of plasma membrane external side of plasma membrane cell surface membrane positive regulation of type II interferon production B cell proliferation cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of apoptotic process positive regulation of B cell differentiation positive regulation of T cell differentiation positive regulation of JNK cascade negative regulation of T cell apoptotic process extrinsic apoptotic signaling pathway	04060
1449184_at	Pglyrp1	peptidoglycan recognition protein 1	7	18884689	NM_009402	21946	41	immune system process cytokine activity extracellular region extracellular space cytoplasm apoptotic process zinc ion binding N-acetylmuramoyl-L-alanine amidase activity peptidoglycan catabolic process response to bacterium peptidoglycan immune receptor activity peptidoglycan immune receptor activity detection of bacterium detection of bacterium Hsp70 protein binding killing of cells of another organism negative regulation of type II interferon production negative regulation of natural killer cell differentiation involved in immune response defense response to bacterium peptidoglycan binding peptidoglycan binding innate immune response receptor ligand activity negative regulation of inflammatory response defense response to Gram-positive bacterium defense response to Gram-positive bacterium biological process involved in interaction with host molecular adaptor activity antimicrobial humoral immune response mediated by antimicrobial peptide
1416731_at	Top2b	topoisomerase (DNA) II beta	14	16365205	BB166592	21974	72	nucleotide binding resolution of meiotic recombination intermediates heterochromatin sister chromatid segregation neuron migration DNA binding chromatin binding DNA topoisomerase activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm cytosol DNA metabolic process DNA topological change axonogenesis isomerase activity B cell differentiation B cell differentiation forebrain development positive regulation of single stranded viral RNA replication via double stranded DNA intermediate metal ion binding
1419494_a_at	Tpd52	tumor protein D52	3	-8926529, -8926529, -8926529	BC002036	21985	32	calcium ion binding protein binding cytoplasm cytoplasm endoplasmic reticulum positive regulation of cell population proliferation B cell differentiation identical protein binding protein homodimerization activity protein homodimerization activity synapse synapse synapse perinuclear region of cytoplasm glutamatergic synapse glutamatergic synapse glutamatergic synapse
1425028_a_at	Tpm2	tropomyosin 2, beta	4	-43513725	BC024358	22004	71	actin binding structural constituent of cytoskeleton protein binding cytoplasm cytoskeleton muscle thin filament tropomyosin actin filament muscle contraction muscle contraction actin filament organization actin cytoskeleton identical protein binding protein homodimerization activity regulation of ATP-dependent activity protein heterodimerization activity actin filament binding actin filament binding	04260 05410 05414
1454851_at	Nr2c2	nuclear receptor subfamily 2, group C, member 2	6	92091417, 92092432	AV162817	22026	113	negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nuclear receptor activity protein binding nucleus nucleoplasm regulation of DNA-templated transcription spermatogenesis zinc ion binding cerebellum development cell differentiation cell differentiation lipopolysaccharide-mediated signaling pathway p38MAPK cascade positive regulation of embryonic development positive regulation of embryonic development sequence-specific DNA binding positive regulation of myoblast differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding positive regulation of behavior anatomical structure development meiotic cell cycle sequence-specific double-stranded DNA binding
1453181_x_at	Plscr1	phospholipid scramblase 1	9	92250193	BF319989	22038	43	magnesium ion binding DNA-binding transcription activator activity, RNA polymerase II-specific virus receptor activity DNA binding nuclease activity epidermal growth factor receptor binding calcium ion binding protein binding nucleus nucleus nucleoplasm nucleolus cytoplasm Golgi apparatus cytosol cytosol plasma membrane plasma membrane plasma membrane phosphatidylserine biosynthetic process lipid transport acute-phase response immune response zinc ion binding membrane hydrolase activity plasma membrane phospholipid scrambling plasma membrane phospholipid scrambling SH3 domain binding phospholipid scramblase activity phospholipid scramblase activity enzyme binding myeloid cell differentiation negative regulation of protein binding lead ion binding regulation of mast cell activation response to interferon-alpha CD4 receptor binding positive regulation of apoptotic process negative regulation of viral genome replication positive regulation of innate immune response membrane raft mercury ion binding perinuclear region of cytoplasm defense response to virus regulation of Fc receptor mediated stimulatory signaling pathway collagen-containing extracellular matrix phosphatidylserine exposure on apoptotic cell surface phosphatidylserine exposure on apoptotic cell surface phosphatidylserine exposure on apoptotic cell surface cellular response to lipopolysaccharide cellular response to cytokine stimulus intrinsic apoptotic signaling pathway positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
1448361_at	Ttc3	tetratricopeptide repeat domain 3	16	94370738	BB833716	22129	33	ubiquitin-protein transferase activity ubiquitin-protein transferase activity protein binding nucleus nucleoplasm nucleolus cytoplasm vacuole Golgi apparatus cytosol ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process transferase activity negative regulation of axon extension negative regulation of neuron differentiation metal ion binding protein K48-linked ubiquitination
1416119_at	Txn1	thioredoxin 1	4	-57943372	NM_011660	22166	146	negative regulation of transcription by RNA polymerase II protein binding extracellular region nucleus nucleus nucleoplasm cytoplasm cytoplasm mitochondrion cytosol cytosol cytosol response to radiation protein-disulfide reductase activity protein-disulfide reductase activity enzyme binding axon dendrite positive regulation of peptidyl-serine phosphorylation protein homodimerization activity neuronal cell body positive regulation of DNA binding cell redox homeostasis cell redox homeostasis negative regulation of protein export from nucleus protein-disulfide reductase (NAD(P)) activity cellular detoxification of hydrogen peroxide response to nitric oxide positive regulation of peptidyl-cysteine S-nitrosylation
1450484_a_at	Cmpk2	cytidine/uridine monophosphate kinase 2	12	26469214	AK004595	22169	20	nucleotide binding cytidylate kinase activity cytidylate kinase activity nucleoside diphosphate kinase activity nucleoside diphosphate kinase activity thymidylate kinase activity thymidylate kinase activity ATP binding nucleoplasm cytoplasm mitochondrion mitochondrion pyrimidine nucleotide biosynthetic process dUDP biosynthetic process dUDP biosynthetic process dTDP biosynthetic process dTDP biosynthetic process dTTP biosynthetic process UMP/dUMP kinase activity kinase activity phosphorylation transferase activity UMP kinase activity nucleoside monophosphate phosphorylation nucleoside monophosphate kinase activity cellular response to lipopolysaccharide	00240 01100
1448230_at	Usp10	ubiquitin specific peptidase 10	8	119910359	NM_009462	22224	51	p53 binding cysteine-type endopeptidase activity cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity protein binding nucleus nucleus nucleoplasm cytoplasm endosome early endosome early endosome cytosol cytosol DNA repair proteolysis autophagy DNA damage response peptidase activity cysteine-type peptidase activity regulation of autophagy regulation of autophagy protein deubiquitination protein deubiquitination hydrolase activity cytosolic ribosome DNA damage response, signal transduction by p53 class mediator DNA damage response, signal transduction by p53 class mediator protein-containing complex monoubiquitinated protein deubiquitination negative regulation of canonical NF-kappaB signal transduction transmembrane transporter binding intermediate filament cytoskeleton negative regulation of stress granule assembly cellular response to interleukin-1 rescue of stalled ribosome molecular function inhibitor activity
1419063_at	Ugt8a	UDP galactosyltransferase 8A	3	-125865271	NM_011674	22239	68	protein localization to paranode region of axon 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity 2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity endoplasmic reticulum endoplasmic reticulum lipid metabolic process sphingolipid metabolic process galactosylceramide biosynthetic process galactosylceramide biosynthetic process cytoskeleton organization ceramide glucosyltransferase activity UDP-glycosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity glycolipid biosynthetic process membrane transferase activity glycosyltransferase activity paranodal junction assembly myelination N-acylsphingosine galactosyltransferase activity neuron projection morphogenesis	00600 01100
1448562_at	Upp1	uridine phosphorylase 1	11	9118007, 9118102, 9118506	NM_009477	22271	47	catalytic activity uridine phosphorylase activity uridine phosphorylase activity uridine phosphorylase activity uridine phosphorylase activity nucleoplasm cytoplasm cytosol cytosol uridine catabolic process uridine catabolic process uridine catabolic process pyrimidine nucleotide metabolic process CMP catabolic process dCMP catabolic process thymidine phosphorylase activity nucleoside metabolic process nucleotide catabolic process transferase activity glycosyltransferase activity pentosyltransferase activity identical protein binding UMP salvage UMP catabolic process dTMP catabolic process dUMP catabolic process uridine metabolic process deoxyuridine phosphorylase activity	00240 00983 01100
1421863_at	Vamp1	vesicle-associated membrane protein 1	6	125215580	AK018783	22317	44	SNAP receptor activity mitochondrion plasma membrane vesicle fusion cell surface membrane synaptic vesicle priming synaptic vesicle priming vesicle-mediated transport syntaxin binding SNARE complex cytoplasmic vesicle neuromuscular junction neuromuscular junction regulation of synaptic vesicle fusion to presynaptic active zone membrane regulation of synaptic vesicle fusion to presynaptic active zone membrane SNARE complex assembly SNARE complex assembly specific granule membrane neuron projection synapse tertiary granule membrane presynapse glutamatergic synapse glutamatergic synapse	04130
1435244_at	Vav2	vav 2 oncogene	2	-27262103	BF535947	22325	109	angiogenesis phosphotyrosine residue binding guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding protein binding cytoplasm cytoplasm cytosol plasma membrane small GTPase-mediated signal transduction cell migration cell migration cell projection assembly lamellipodium assembly intracellular signal transduction regulation of GTPase activity regulation of GTPase activity metal ion binding positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	04062 04510 04650 04660 04662 04664 04666 04670 04810
1451562_at	Ggact	gamma-glutamylamine cyclotransferase	14	-122890859	BC006662	223267	12	cytosol lyase activity cellular modified amino acid catabolic process gamma-glutamylaminecyclotransferase activity
1435375_at	Otulinl	OTU deubiquitinase with linear linkage specificity like	15	-27655070	BM224662	223433	16	molecular_function nucleus nuclear envelope cytoplasm endoplasmic reticulum biological_process membrane cytoplasmic side of endoplasmic reticulum membrane
1455555_at	Vipr1	vasoactive intestinal peptide receptor 1	9	121642715	BF224468	22354	46	transmembrane signaling receptor activity G protein-coupled receptor activity vasoactive intestinal polypeptide receptor activity vasoactive intestinal polypeptide receptor activity plasma membrane plasma membrane signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger adenylate cyclase-modulating G protein-coupled receptor signaling pathway G protein-coupled peptide receptor activity membrane peptide hormone binding peptide hormone binding receptor complex	04080
1422921_at	Vpreb3	V-set pre-B cell surrogate light chain 3	10	75948299	NM_009514	22364	18	immunoglobulin production negative regulation of immunoglobulin production molecular_function extracellular space endoplasmic reticulum immune response
1455197_at	Rnd1	Rho family GTPase 1	15	-98669204	BE852181	223881	19	nucleotide binding GTPase activity GTPase activity signaling receptor binding GTP binding GTP binding cytoplasm cytosol cytosol cytoskeleton plasma membrane plasma membrane adherens junction actin filament organization actin filament organization negative regulation of cell adhesion signal transduction small GTPase-mediated signal transduction actin cytoskeleton membrane neuron remodeling cell migration protein kinase binding regulation of actin cytoskeleton organization intracellular membrane-bounded organelle	04360
1455337_at	Fgd4	FYVE, RhoGEF and PH domain containing 4	16	-16416914, -16416914, -16416914	BQ175875	224014	32	actin binding guanyl-nucleotide exchange factor activity cytoplasm cytoplasm cytoskeleton cytoskeleton organization regulation of cell shape lamellipodium lamellipodium assembly microspike assembly filopodium cell projection positive regulation of JUN kinase activity positive regulation of JNK cascade filopodium assembly metal ion binding actin filament binding
1434513_at	Atp13a3	ATPase type 13A3	16	-30312423	BQ030867	224088	16	nucleotide binding transporter activity ATP binding endosome intracellular calcium ion homeostasis polyamine transmembrane transporter activity ABC-type putrescine transporter activity P-type ion transporter activity membrane ATP hydrolysis activity ATPase-coupled monoatomic cation transmembrane transporter activity ATPase-coupled monoatomic cation transmembrane transporter activity early endosome membrane late endosome membrane late endosome membrane metal ion binding recycling endosome membrane P-type transmembrane transporter activity polyamine transmembrane transport
1437223_s_at	Xbp1	X-box binding protein 1	11	5520640	AV051768	22433	402	negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding angiogenesis regulation of cell growth liver development positive regulation of protein phosphorylation endothelial cell proliferation endothelial cell proliferation protease binding glandular epithelial cell maturation positive regulation of immunoglobulin production positive regulation of immunoglobulin production DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity nucleus nucleus nucleus cytoplasm cytoplasm endoplasmic reticulum endoplasmic reticulum membrane cytosol regulation of DNA-templated transcription regulation of transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II ubiquitin-dependent protein catabolic process lipid metabolic process autophagy apoptotic process response to unfolded protein multicellular organism development muscle organ development positive regulation of cell population proliferation response to xenobiotic stimulus regulation of autophagy positive regulation of autophagy negative regulation of myotube differentiation protein transport membrane protein kinase binding cell differentiation positive regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway endoplasmic reticulum unfolded protein response endoplasmic reticulum unfolded protein response endoplasmic reticulum unfolded protein response exocrine pancreas development chromatin DNA binding ubiquitin protein ligase binding regulation of protein stability protein destabilization protein destabilization cellular response to nutrient positive regulation of TOR signaling positive regulation of interleukin-6 production cellular response to insulin stimulus cellular response to oxidative stress response to endoplasmic reticulum stress response to endoplasmic reticulum stress intracellular triglyceride homeostasis positive regulation of vascular wound healing cellular response to vascular endothelial growth factor stimulus phosphatidylinositol 3-kinase regulatory subunit binding cellular response to glucose starvation positive regulation of protein import into nucleus cholesterol homeostasis identical protein binding histone deacetylase binding negative regulation of apoptotic process phosphatidylinositol 3-kinase/protein kinase B signal transduction sequence-specific DNA binding sequence-specific DNA binding ubiquitin-like protein ligase binding positive regulation of MHC class II biosynthetic process positive regulation of B cell differentiation positive regulation of T cell differentiation positive regulation of fat cell differentiation positive regulation of angiogenesis positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein heterodimerization activity vascular endothelial growth factor receptor signaling pathway neuron development response to electrical stimulus fatty acid homeostasis sterol homeostasis serotonin secretion, neurotransmission adipose tissue development epithelial cell maturation involved in salivary gland development intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress negative regulation of ERK1 and ERK2 cascade cellular response to lipopolysaccharide cellular response to lipopolysaccharide cellular response to amino acid stimulus cellular response to fructose stimulus cellular response to glucose stimulus cellular response to interleukin-4 cellular response to peptide hormone stimulus cellular response to fluid shear stress cellular response to laminar fluid shear stress RNA polymerase II transcription regulator complex positive regulation of plasma cell differentiation negative regulation of endoplasmic reticulum unfolded protein response positive regulation of endoplasmic reticulum unfolded protein response positive regulation of protein acetylation negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway positive regulation of lactation response to insulin-like growth factor stimulus cellular response to leukemia inhibitory factor sequence-specific double-stranded DNA binding positive regulation of hepatocyte proliferation positive regulation of endothelial cell apoptotic process	04141
1451006_at	Xdh	xanthine dehydrogenase	17	-73883894	AV286265	22436	95	allantoin metabolic process allantoin metabolic process allantoin metabolic process negative regulation of protein phosphorylation negative regulation of endothelial cell proliferation xanthine dehydrogenase activity xanthine dehydrogenase activity xanthine dehydrogenase activity xanthine dehydrogenase activity xanthine oxidase activity xanthine oxidase activity xanthine oxidase activity iron ion binding protein binding extracellular region extracellular space extracellular space cytoplasm peroxisome cytosol cytosol cytosol guanine catabolic process guanine catabolic process inosine catabolic process inosine catabolic process inosine catabolic process deoxyinosine catabolic process deoxyinosine catabolic process deoxyinosine catabolic process adenosine catabolic process adenosine catabolic process adenosine catabolic process deoxyadenosine catabolic process deoxyguanosine catabolic process AMP catabolic process AMP catabolic process IMP catabolic process IMP catabolic process activation of cysteine-type endopeptidase activity involved in apoptotic process lactation hypoxanthine catabolic process hypoxanthine catabolic process hypoxanthine catabolic process xanthine catabolic process xanthine catabolic process xanthine catabolic process response to aluminum ion negative regulation of gene expression iron-sulfur cluster assembly oxidoreductase activity sarcoplasmic reticulum molybdenum ion binding regulation of epithelial cell differentiation identical protein binding protein homodimerization activity molybdopterin cofactor binding amide catabolic process amide catabolic process amide catabolic process negative regulation of endothelial cell differentiation GMP catabolic process dGMP catabolic process dAMP catabolic process metal ion binding nitrite reductase (NO-forming) activity flavin adenine dinucleotide binding iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction hypoxanthine dehydrogenase activity hypoxanthine dehydrogenase activity hypoxanthine dehydrogenase activity hypoxanthine oxidase activity hypoxanthine oxidase activity hypoxanthine oxidase activity FAD binding positive regulation of p38MAPK cascade negative regulation of vascular endothelial growth factor signaling pathway positive regulation of reactive oxygen species metabolic process negative regulation of vasculogenesis	00230 00232 00983 01100 04146
1425058_at	Zfp472	zinc finger protein 472	17	32965830	BC023090	224691	18	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II
1439505_at	Clic5	chloride intracellular channel 5	17	44188571	AA210377	224796	35	response to dietary excess diet induced thermogenesis chloride channel activity chloride channel activity cytoplasm cytoplasm mitochondrion Golgi apparatus cytoskeleton plasma membrane plasma membrane monoatomic ion transport chloride transport chloride transport visual perception sensory perception of sound sensory perception of sound protein localization actin cytoskeleton membrane membrane stereocilium stereocilium bundle monoatomic ion transmembrane transport monoatomic ion channel complex chloride channel complex neuromuscular process controlling balance response to stimulus auditory receptor cell stereocilium organization
1459805_x_at	Dus3l	dihydrouridine synthase 3 like	17	56764750	BB482412	224907	20	tRNA dihydrouridine synthesis mRNA processing regulation of translation tRNA processing oxidoreductase activity tRNA dihydrouridine synthase activity tRNA dihydrouridine synthase activity metal ion binding flavin adenine dinucleotide binding tRNA-dihydrouridine47 synthase activity mRNA dihydrouridine synthase activity
1424641_a_at	Thoc1	THO complex 1	18	9958179	BC024951	225160	36	transcription export complex THO complex THO complex part of transcription export complex THO complex part of transcription export complex chromosome, telomeric region DNA binding RNA binding protein binding nucleus cytoplasm mRNA processing mRNA export from nucleus mRNA export from nucleus apoptotic process signal transduction RNA splicing nuclear speck regulation of DNA-templated transcription elongation regulation of apoptotic process mRNA transport	03013 03040
1428837_at	Klhl14	kelch-like 14	18	-21550378	AK018108	225266	18	protein binding cytoplasm cytoplasm endoplasmic reticulum endoplasmic reticulum cytosol actin cytoskeleton membrane aggresome neuron projection neuron projection neuronal cell body neuronal cell body
1451277_at	Ptgr3	prostaglandin reductase 3	18	84088157	BC025897	225791	18	mitochondrion peroxisome lipid metabolic process zinc ion binding oxidoreductase activity 13-prostaglandin reductase activity 13-prostaglandin reductase activity negative regulation of fat cell differentiation 15-oxoprostaglandin 13-oxidase activity
1433537_at	Atrx	ATRX, chromatin remodeler	X	-105797614	AV112912	22589	138	nucleotide binding meiotic spindle organization nuclear chromosome condensed chromosome, centromeric region chromosome, telomeric region heterochromatin DNA binding chromatin binding chromatin binding helicase activity protein binding ATP binding nucleus nucleus nucleoplasm chromosome pericentric heterochromatin pericentric heterochromatin DNA repair chromatin organization nucleosome assembly chromatin remodeling chromatin remodeling transcription by RNA polymerase II DNA damage response spermatogenesis positive regulation of nuclear cell cycle DNA replication DNA translocase activity nuclear body PML body hydrolase activity DNA damage response, signal transduction by p53 class mediator forebrain development replication fork processing replication fork processing chromatin DNA binding subtelomeric heterochromatin formation subtelomeric heterochromatin formation positive regulation of telomere maintenance methylated histone binding methylated histone binding post-embryonic forelimb morphogenesis multicellular organism growth histone binding histone binding histone binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding Sertoli cell development chromo shadow domain binding chromosome organization involved in meiotic cell cycle protein localization to chromosome, telomeric region seminiferous tubule development cellular response to hydroxyurea chromosome, subtelomeric region ATP-dependent chromatin remodeler activity negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric
1460366_at	Eml3	echinoderm microtubule associated protein like 3	19	8929693, 8929662	BC022146	225898	16	microtubule cytoskeleton organization nucleus cytoplasm spindle cytoskeleton microtubule spindle microtubule cell cycle mitotic metaphase chromosome alignment microtubule binding microtubule cytoskeleton midbody protein self-association cell division mitotic spindle regulation of mitotic spindle assembly mitotic spindle microtubule
1434245_a_at	Cyb561a3	cytochrome b561 family, member A3	19	10577156, 10577447	BB218627	225912	14	nucleolus lysosome lysosomal membrane lysosomal membrane endosome intracellular iron ion homeostasis membrane oxidoreductase activity oxidoreductase activity late endosome membrane intracellular membrane-bounded organelle metal ion binding transmembrane ascorbate ferrireductase activity
1433771_at	Abhd17b	abhydrolase domain containing 17B	19	21653308	AV173092	226016	18	protein depalmitoylation protein depalmitoylation protein depalmitoylation endosome plasma membrane plasma membrane proteolysis serine-type peptidase activity palmitoyl-(protein) hydrolase activity palmitoyl-(protein) hydrolase activity palmitoyl-(protein) hydrolase activity endosome membrane postsynaptic density membrane hydrolase activity cell projection synapse postsynaptic membrane recycling endosome membrane postsynaptic density membrane postsynaptic recycling endosome membrane glutamatergic synapse regulation of postsynapse organization regulation of postsynapse organization regulation of protein localization to synapse negative regulation of protein localization to microtubule regulation of dendritic spine maintenance positive regulation of protein localization to endosome
1427318_s_at	Myof	myoferlin	19	-37899035	BI555209	226101	45	plasma membrane repair plasma membrane repair phospholipid binding phospholipid binding phospholipid binding nucleus plasma membrane plasma membrane caveola glycerol metabolic process membrane regulation of vascular endothelial growth factor receptor signaling pathway cytoplasmic vesicle T-tubule organization T-tubule organization centriolar satellite cellular response to heat intracellular membrane-bounded organelle metal ion binding muscle cell development membrane fusion
1454708_at	Ablim1	actin-binding LIM protein 1	19	-57032732, -57032732, -57032732, -57032732, -57032732	BG065289	226251	51	stress fiber stress fiber actin binding protein binding cytoplasm cytoskeleton transcription by RNA polymerase II cytoskeleton organization axon guidance postsynaptic density actin cytoskeleton actin cytoskeleton lamellipodium lamellipodium assembly lamellipodium assembly positive regulation of transcription by RNA polymerase II metal ion binding actin filament binding cilium assembly cilium assembly	04360
1419922_s_at	Atrnl1	attractin like 1	19	57611033	AW555641	226255	20	Notch binding protein binding plasma membrane G protein-coupled receptor signaling pathway membrane carbohydrate binding
1455544_at	Zranb3	zinc finger, RAN-binding domain containing 3	1	-127954178, -127954178, -127954178	BM228797	226409	21	nucleotide binding nucleic acid binding catalytic activity helicase activity nuclease activity endonuclease activity DNA endonuclease activity DNA endonuclease activity ATP binding nucleus nucleoplasm chromosome DNA repair DNA repair DNA damage response metabolic process zinc ion binding response to UV hydrolase activity replication fork processing replication fork processing DNA rewinding ATP-dependent DNA/DNA annealing activity nuclear replication fork nuclear replication fork negative regulation of DNA recombination metal ion binding K63-linked polyubiquitin modification-dependent protein binding replication fork reversal ATP-dependent chromatin remodeler activity
1457035_at	Ifi207	interferon activated gene 207	1	-173723427	AI607873	226691	13	negative regulation of transcription by RNA polymerase II activation of innate immune response activation of innate immune response double-stranded DNA binding double-stranded DNA binding nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol cytosol transcription factor binding monocyte differentiation positive regulation of interleukin-1 beta production cellular response to interferon-beta cellular response to glucose starvation identical protein binding negative regulation of DNA binding negative regulation of viral genome replication negative regulation of gene expression, epigenetic negative regulation of innate immune response negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II defense response to virus cellular response to ionizing radiation intrinsic apoptotic signaling pathway by p53 class mediator activation of cysteine-type endopeptidase activity negative regulation of AIM2 inflammasome complex assembly negative regulation of cysteine-type endopeptidase activity
1423962_at	Wdr26	WD repeat domain 26	1	-181173225	BC020044	226757	29	ubiquitin ligase complex molecular_function nucleus nucleoplasm cytoplasm mitochondrion cytosol GID complex proteasome-mediated ubiquitin-dependent protein catabolic process
1455816_a_at	Kctd3	potassium channel tetramerisation domain containing 3	1	-188971095, -188971097	BB321232	226823	18	molecular_function protein binding plasma membrane biological_process membrane protein homooligomerization
1424706_at	Zfp51	zinc finger protein 51	17	21450373	BC011183	22709	19	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II
1425495_at	Zfp62	zinc finger protein 62	11	49203291, 49203730, 49204318	BC022935	22720	23	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific nucleus nucleus regulation of transcription by RNA polymerase II metal ion binding
1433564_at	Dgkd	diacylglycerol kinase, delta	1	87853286	BB094429	227333	35	nucleotide binding ATP-dependent diacylglycerol kinase activity ATP-dependent diacylglycerol kinase activity ATP-dependent diacylglycerol kinase activity ATP binding cytoplasm cytosol plasma membrane clathrin-coated pit lipid metabolic process phosphatidic acid biosynthetic process endocytosis signal transduction protein kinase C-activating G protein-coupled receptor signaling pathway protein transport membrane kinase activity phosphorylation transferase activity kinase binding cytoplasmic vesicle intracellular signal transduction identical protein binding protein homodimerization activity positive regulation of epidermal growth factor receptor signaling pathway diacylglycerol metabolic process diacylglycerol metabolic process diacylglycerol metabolic process lipid phosphorylation lipid phosphorylation lipid phosphorylation metal ion binding protein heterodimerization activity negative regulation of protein kinase C signaling positive regulation of clathrin-dependent endocytosis	00561 00564 01100 04070
1437870_at	Slco4c1	solute carrier organic anion transporter family, member 4C1	1	-96818783	AV024403	227394	28	plasma membrane monoatomic ion transport multicellular organism development spermatogenesis organic anion transmembrane transporter activity sodium-independent organic anion transmembrane transporter activity organic anion transport membrane basolateral plasma membrane basolateral plasma membrane transmembrane transporter activity cell differentiation sodium-independent organic anion transport transmembrane transport
1436312_at	Ikzf1	IKAROS family zinc finger 1	11	11690176, 11685924	AV317621	22778	243	negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific natural killer cell differentiation DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleoplasm transcription regulator complex pericentric heterochromatin pericentric heterochromatin cytoplasm cytosol chromatin organization regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cell cycle multicellular organism development poly-pyrimidine tract binding positive regulation of gene expression protein domain specific binding hemopoiesis lymphocyte differentiation B cell differentiation T cell differentiation erythrocyte differentiation forebrain development positive regulation of transcription elongation by RNA polymerase II protein-containing complex protein-DNA complex amacrine cell differentiation positive regulation of multicellular organism growth positive regulation of multicellular organism growth identical protein binding sequence-specific DNA binding establishment of protein localization positive regulation of neutrophil differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of RNA polymerase II transcription preinitiation complex assembly positive regulation of transcription by RNA polymerase II metal ion binding lymph node development thymus development Peyer's patch development gland development retinal bipolar neuron differentiation
1436649_at	Ikzf3	IKAROS family zinc finger 3	11	-98464692	BB151746	22780	57	RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol regulation of transcription by RNA polymerase II response to bacterium B cell differentiation T cell differentiation regulation of B cell proliferation B cell activation identical protein binding protein homodimerization activity histone deacetylase binding regulation of apoptotic process sequence-specific DNA binding sequence-specific DNA binding regulation of B cell differentiation regulation of lymphocyte differentiation positive regulation of transcription by RNA polymerase II metal ion binding protein heterodimerization activity promoter-specific chromatin binding
1451451_at	Gca	grancalcin	2	62664326	BC021450	227960	21	calcium ion binding calcium ion binding cytoplasm cytosol cytosol plasma membrane membrane protein homodimerization activity metal ion binding protein heterodimerization activity
1451141_at	Mettl8	methyltransferase 8, methylcytidine	2	-70964560, -70964561	BC004636	228019	21	histone acetyltransferase activity nucleus cytoplasm mitochondrion skeletal muscle tissue development tRNA processing methyltransferase activity mRNA methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity transferase activity methylation fat cell differentiation tRNA (cytidine-3-)-methyltransferase activity positive regulation of mitochondrial translation mitochondrial tRNA modification mRNA methylation mRNA methylation tRNA C3-cytosine methylation
1455080_at	Ppp1r16b	protein phosphatase 1, regulatory subunit 16B	2	158667134, 158666732	BB375209	228852	25	positive regulation of endothelial cell proliferation enzyme inhibitor activity nucleus cytoplasm plasma membrane membrane nuclear speck myosin phosphatase regulator activity protein phosphatase regulator activity regulation of protein dephosphorylation positive regulation of protein dephosphorylation negative regulation of protein dephosphorylation cell projection perinuclear region of cytoplasm regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction establishment of endothelial barrier establishment of endothelial barrier establishment of endothelial barrier negative regulation of peptidyl-serine dephosphorylation positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis regulation of sprouting angiogenesis
1452922_at	Ppp1r3d	protein phosphatase 1, regulatory subunit 3D	2	-178411205	AK011539	228966	12	protein phosphatase type 1 complex phosphoprotein phosphatase activity regulation of glycogen biosynthetic process regulation of glycogen biosynthetic process regulation of glycogen catabolic process protein phosphatase 1 binding enzyme binding glycogen granule glycogen binding	04910
1425062_at	Fcrl1	Fc receptor-like 1	3	87376386, 87376386	BF163263	229499	18	plasma membrane cell surface coreceptor activity membrane B cell activation
1455046_a_at	Pogz	pogo transposable element with ZNF domain	3	94837436	BI250645	229584	44	double-strand break repair via homologous recombination chromatin nucleic acid binding DNA binding nucleus nucleus nucleoplasm chromosome cytoplasm cytosol DNA repair DNA recombination DNA damage response cell cycle mitotic sister chromatid cohesion positive regulation of transcription by RNA polymerase II metal ion binding cell division kinetochore assembly
1451932_a_at	Adamtsl4	ADAMTS-like 4	3	-95676200	BC016215	229595	23	protease binding epithelial cell development extracellular region interstitial matrix apoptotic process extracellular matrix organization extracellular matrix organization extracellular matrix identical protein binding positive regulation of apoptotic process pigment cell development
1435174_at	Rsbn1	rosbin, round spermatid basic protein 1	3	103914119	AW546080	229675	23	protein binding nucleus nucleus chromatin organization biological_process oxidoreductase activity histone H4K20 demethylase activity metal ion binding dioxygenase activity
1452717_at	Slc25a24	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24	3	109123148	BM230959	229731	25	adenine nucleotide transmembrane transporter activity ATP transmembrane transporter activity ATP transmembrane transporter activity calcium ion binding mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial transport antiporter activity ADP transport ATP transport membrane cellular response to oxidative stress metal ion binding adenine nucleotide transport transmembrane transport cellular response to calcium ion ATP:inorganic phosphate antiporter activity ADP:inorganic phosphate antiporter activity mitochondrial ATP transmembrane transport
1434380_at	Gbp7	guanylate binding protein 7	3	142530335	BM241271	229900	19	nucleotide binding activation of innate immune response immune system process GTPase activity GTPase activity protein binding GTP binding GTP binding membrane hydrolase activity symbiont-containing vacuole membrane cytoplasmic vesicle cytoplasmic vesicle cellular response to interferon-beta defense response to bacterium defense response to protozoan defense response to protozoan defense response to protozoan adhesion of symbiont to host innate immune response defense response to Gram-positive bacterium defense response to Gram-positive bacterium defense response to virus cytolysis in another organism cellular response to type II interferon cellular response to type II interferon
1437760_at	Galnt12	polypeptide N-acetylgalactosaminyltransferase 12	4	47091922	AV376137	230145	22	molecular_function polypeptide N-acetylgalactosaminyltransferase activity polypeptide N-acetylgalactosaminyltransferase activity Golgi apparatus Golgi apparatus protein O-linked glycosylation biological_process membrane transferase activity glycosyltransferase activity carbohydrate binding metal ion binding	00512 01100
1426315_a_at	Tmem268	transmembrane protein 268	4	63558762, 63560226	AV326978	230279	12	molecular_function cellular_component biological_process membrane
1433968_a_at	Megf9	multiple EGF-like-domains 9	4	-70431926	BQ174710	230316	22	extracellular matrix structural constituent basement membrane basement membrane axon guidance animal organ morphogenesis tissue development membrane
1437395_at	Tut4	terminal uridylyl transferase 4	4	108460007, 108459409	BE370775	230594	33	oocyte maturation cytokine production nucleic acid binding protein binding nucleus nucleolus cytoplasm cytoplasm cytosol cytosol zinc ion binding miRNA metabolic process miRNA metabolic process miRNA catabolic process transferase activity nucleotidyltransferase activity stem cell population maintenance regulatory ncRNA-mediated gene silencing pre-miRNA processing RNA 3'-end processing RNA 3'-end processing regulation of lipopolysaccharide-mediated signaling pathway negative regulation of NF-kappaB transcription factor activity positive regulation of interleukin-6 production miRNA binding cytoplasmic ribonucleoprotein granule metal ion binding RNA uridylyltransferase activity RNA uridylyltransferase activity RNA uridylyltransferase activity RNA uridylyltransferase activity interleukin-6-mediated signaling pathway uridylyltransferase activity uridylyltransferase activity RNA 3' uridylation RNA 3' uridylation RNA 3' uridylation retrotransposon silencing by mRNA destabilization polyuridylation-dependent mRNA catabolic process
1440819_s_at	Szt2	SZT2 subunit of KICSTOR complex	4	-118362739	BB541793	230676	28	lysosome lysosomal membrane peroxisome peroxisome central nervous system development post-embryonic development membrane corpus callosum morphogenesis response to nutrient levels cellular response to amino acid starvation cellular response to glucose starvation pigmentation protein localization to lysosome GATOR2 complex KICSTOR complex regulation of superoxide dismutase activity negative regulation of TORC1 signaling negative regulation of TORC1 signaling GATOR1 complex
1435362_at	Foxj3	forkhead box J3	4	119539660, 119542335	BB026073	230700	38	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus regulation of DNA-templated transcription regulation of transcription by RNA polymerase II male meiosis I spermatogenesis cell differentiation sequence-specific DNA binding positive regulation of transcription by RNA polymerase II meiotic cell cycle sequence-specific double-stranded DNA binding
1435087_at	Zfp362	zinc finger protein 362	4	-128773084	BI409907	230761	7	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity regulation of transcription by RNA polymerase II
1428467_at	Tardbp	TAR DNA binding protein	4	-148612381	AK004440	230908	286	RNA polymerase II cis-regulatory region sequence-specific DNA binding negative regulation of protein phosphorylation nucleic acid binding DNA binding double-stranded DNA binding RNA binding RNA binding RNA binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleoplasm nucleoplasm perichromatin fibrils cytoplasm mitochondrion mRNA processing lipid binding RNA splicing RNA splicing gene expression regulation of gene expression negative regulation of gene expression nuclear speck regulation of protein stability regulation of protein stability positive regulation of insulin secretion interchromatin granule positive regulation of protein import into nucleus regulation of circadian rhythm identical protein binding regulation of apoptotic process intracellular non-membrane-bounded organelle negative regulation by host of viral transcription rhythmic process regulation of cell cycle 3'-UTR-mediated mRNA destabilization 3'-UTR-mediated mRNA stabilization nuclear inner membrane organization pre-mRNA intronic binding molecular condensate scaffold activity amyloid fibril formation
1423919_at	Haus3	HAUS augmin-like complex, subunit 3	5	-34153896	BC027393	231123	26	cytoplasm centrosome centrosome cytoskeleton microtubule cell cycle centrosome cycle centrosome cycle spindle assembly spindle assembly cell division HAUS complex HAUS complex mitotic spindle mitotic spindle microtubule
1437184_at	Guf1	GUF1 homolog, GTPase	5	69556923	BI789973	231279	18	nucleotide binding GTPase activity GTP binding mitochondrion mitochondrion mitochondrial inner membrane translation membrane hydrolase activity positive regulation of translation mitochondrial ribosome binding
1434311_at	Cnot6l	CCR4-NOT transcription complex, subunit 6-like	5	-96070332, -96070332, -96070332	BB025078	231464	43	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay nuclear-transcribed mRNA poly(A) tail shortening catalytic activity nuclease activity exonuclease activity poly(A)-specific ribonuclease activity poly(A)-specific ribonuclease activity poly(A)-specific ribonuclease activity protein binding nucleus nucleus cytoplasm cytoplasm cytoplasm cytosol cytosol mRNA processing regulation of translation positive regulation of cell population proliferation positive regulation of cell population proliferation positive regulation of cytoplasmic mRNA processing body assembly hydrolase activity CCR4-NOT complex CCR4-NOT complex regulatory ncRNA-mediated gene silencing metal ion binding mRNA destabilization	03018
1451335_at	Plac8	placenta-specific 8	5	-100553725, -100553725	AF263458	231507	39	chromatin binding protein binding nucleus transcription by RNA polymerase II transcription by RNA polymerase II positive regulation of cell population proliferation response to cold negative regulation of multicellular organism growth defense response to bacterium negative regulation of apoptotic process negative regulation of apoptotic process positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II brown fat cell differentiation positive regulation of cold-induced thermogenesis
1454799_at	Gpat3	glycerol-3-phosphate acyltransferase 3	5	100846228	AV300264	231510	22	1-acylglycerol-3-phosphate O-acyltransferase activity glycerol-3-phosphate O-acyltransferase activity protein binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane glycerol-3-phosphate metabolic process lipid metabolic process O-acyltransferase activity phospholipid biosynthetic process membrane transferase activity acyltransferase activity triglyceride biosynthetic process triglyceride biosynthetic process regulation of TOR signaling sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity	00561 00564 01100
1455370_at	A630023P12Rik	RIKEN cDNA A630023P12 gene	5	110514922	AI451630	231603	10	molecular_function cellular_component biological_process
1424339_at	Oasl1	2'-5' oligoadenylate synthetase-like 1	5	114923239	AB067533	231655	28	immune system process DNA binding RNA binding double-stranded RNA binding double-stranded RNA binding double-stranded RNA binding nucleus nucleoplasm nucleoplasm nucleolus cytoplasm cytosol cytosol response to virus membrane nucleotidyltransferase activity negative regulation of viral genome replication negative regulation of viral genome replication innate immune response defense response to virus defense response to virus regulation of ribonuclease activity interleukin-27-mediated signaling pathway positive regulation of RIG-I signaling pathway
1428346_at	Trafd1	TRAF type zinc finger domain containing 1	5	-121371724, -121371724	AK003586	231712	21	protein binding mitochondrion zinc ion binding negative regulation of innate immune response negative regulation of innate immune response metal ion binding
1438675_at	Sfswap	splicing factor SWAP	5	129501230, 129501239	BB278628	231769	26	alternative mRNA splicing, via spliceosome mRNA 5'-splice site recognition mRNA 5'-splice site recognition RNA binding protein binding nucleus RNA processing mRNA processing RNA splicing negative regulation of mRNA splicing, via spliceosome
1427327_at	Pilra	paired immunoglobin-like type 2 receptor alpha	5	-137821951	BB775785	231805	28	protein binding signal transduction membrane MHC class I protein binding
1456762_at	Gimap6	GTPase, IMAP family member 6	6	-48701582	BM237714	231931	18	nucleotide binding molecular_function GTP binding cytoplasm cytosol cytosol biological_process
1438630_x_at	Mat2a	methionine adenosyltransferase 2A	6	-72432795	AV260654	232087	50	nucleotide binding methionine adenosyltransferase activity methionine adenosyltransferase activity methionine adenosyltransferase activity ATP binding cytosol S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process S-adenosylmethionine biosynthetic process one-carbon metabolic process circadian rhythm response to xenobiotic stimulus response to hormone amino acid binding transferase activity protein hexamerization small molecule binding identical protein binding metal ion binding methionine adenosyltransferase complex methionine adenosyltransferase complex protein heterooligomerization response to cAMP cellular response to leukemia inhibitory factor	00270 01100
1451125_at	Paip2b	poly(A) binding protein interacting protein 2B	6	-83806058	BC017133	232164	21	mRNA regulatory element binding translation repressor activity cytoplasm regulation of translation poly(A) binding negative regulation of translation negative regulation of translation translation repressor activity negative regulation of translational initiation
1426988_at	Klhl42	kelch-like 42	6	147091074	BB795533	232539	16	protein polyubiquitination protein polyubiquitination ubiquitin-protein transferase activity cytoplasm cytoskeleton cell cycle Cul3-RING ubiquitin ligase complex Cul3-RING ubiquitin ligase complex regulation of microtubule-based process regulation of microtubule-based process proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process cell division
1456777_at	Mgam	maltase-glucoamylase	6	40628830, 40628830	BB072761	232714	19	maltose catabolic process glucan 1,4-alpha-glucosidase activity alpha-1,4-glucosidase activity alpha-1,4-glucosidase activity alpha-1,4-glucosidase activity amylase activity apical plasma membrane maltose alpha-glucosidase activity alpha-glucosidase activity dextrin catabolic process	00052 00500 01100 04973
1425128_at	B3gnt8	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8	7	25627623	BC025206	232984	13	Golgi membrane Golgi apparatus protein glycosylation protein O-linked glycosylation membrane protein N-acetylglucosaminyltransferase activity protein N-acetylglucosaminyltransferase activity transferase activity glycosyltransferase activity hexosyltransferase activity poly-N-acetyllactosamine biosynthetic process poly-N-acetyllactosamine biosynthetic process
1425380_at	Rasgrp4	RAS guanyl releasing protein 4	7	29134932	AF331457	233046	24	guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity nucleoplasm cytoplasm cytosol plasma membrane plasma membrane small GTPase-mediated signal transduction Ras protein signal transduction cell population proliferation response to extracellular stimulus membrane cell differentiation positive regulation of GTPase activity positive regulation of Ras protein signal transduction metal ion binding	04010
1425216_at	Ffar2	free fatty acid receptor 2	7	-30818356, -30818356, -30818356, -30818356, -30818356	AV370830	233079	103	leukocyte chemotaxis involved in inflammatory response immune system process mucosal immune response regulation of acute inflammatory response positive regulation of cytokine production involved in immune response cell surface pattern recognition receptor signaling pathway positive regulation of acute inflammatory response to non-antigenic stimulus G protein-coupled receptor activity G protein-coupled receptor activity G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane inflammatory response signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway phospholipase C-activating G protein-coupled receptor signaling pathway lipid binding membrane lipid storage lipid storage positive regulation of insulin secretion positive regulation of chemokine production positive regulation of interleukin-8 production glucose homeostasis glucose homeostasis cell projection fat cell differentiation negative regulation of insulin secretion negative regulation of insulin secretion cellular response to fatty acid cellular response to fatty acid cellular response to fatty acid cellular response to fatty acid regulation of peptide hormone secretion regulation of peptide hormone secretion ligand-gated ion channel signaling pathway
1460620_at	Zfp592	zinc finger protein 592	7	80993683	BB668116	233410	30	DNA binding protein binding nucleus PH domain binding insulin receptor substrate binding negative regulation of insulin receptor signaling pathway metal ion binding regulation of peptidyl-tyrosine phosphorylation
1452857_at	Crebzf	CREB/ATF bZIP transcription factor	7	90442780	AW546339	233490	31	DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm mitochondrion regulation of DNA-templated transcription regulation of transcription by RNA polymerase II response to virus regulation of gene expression identical protein binding sequence-specific DNA binding negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II regulation of DNA-binding transcription factor activity RNA polymerase II transcription regulator complex
1455452_x_at	Kctd14	potassium channel tetramerisation domain containing 14	7	97451333, 97453203	AW552116	233529	14	molecular_function cellular_component biological_process
1451342_at	Spon1	spondin 1, (f-spondin) extracellular matrix protein	7	113765997	BC020531	233744	54	extracellular matrix structural constituent protein binding extracellular region cell adhesion cell adhesion positive regulation of protein processing protein processing extracellular matrix positive regulation of protein binding metal ion binding LBD domain binding collagen-containing extracellular matrix negative regulation of amyloid-beta formation positive regulation of amyloid precursor protein catabolic process
1428539_at	Smg1	SMG1 nonsense mediated mRNA decay associated PI3K related kinase	7	-118131311	AK011909	233789	32	nucleotide binding nuclear-transcribed mRNA catabolic process, nonsense-mediated decay nuclear-transcribed mRNA catabolic process, nonsense-mediated decay protein serine/threonine kinase activity protein serine/threonine kinase activity diacylglycerol-dependent serine/threonine kinase activity ATP binding nucleus nucleus nucleoplasm cytoplasm DNA repair protein phosphorylation DNA damage response kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation regulation of telomere maintenance chromatoid body telomeric DNA binding protein autophosphorylation phosphatidylinositol phosphate biosynthetic process metal ion binding	03015
1455141_at	Tnrc6a	trinucleotide repeat containing 6a	7	123123884	BI080625	233833	40	P-body P-body P-body nucleic acid binding RNA binding nucleoplasm nucleoplasm cytoplasm Golgi apparatus cytosol regulation of translation endoderm development cellular response to starvation RISC complex regulatory ncRNA-mediated gene silencing maintenance of protein location in cell miRNA-mediated post-transcriptional gene silencing miRNA-mediated post-transcriptional gene silencing miRNA-mediated gene silencing by inhibition of translation intracellular membrane-bounded organelle perinuclear region of cytoplasm molecular adaptor activity positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
1433598_at	Arglu1	arginine and glutamate rich 1	8	-8666575	BG093966	234023	20	nucleoplasm nucleoplasm mitochondrion mitochondrion cytosol
1424599_at	Fgl1	fibrinogen-like protein 1	8	-41191433	BC021946	234199	28	adaptive immune response immune system process signaling receptor binding protein binding extracellular region extracellular region extracellular space cell-matrix adhesion cholesterol metabolic process regulation of glucose metabolic process response to stilbenoid identical protein binding regulation of immune response regulation of immune response negative regulation of T cell activation negative regulation of T cell activation adipose tissue development collagen-containing extracellular matrix platelet aggregation hepatocyte proliferation
1451777_at	Ddx60	DExD/H box helicase 60	8	61928086	BC013672	234311	19	double-stranded DNA binding RNA binding double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding protein binding cytoplasm cytoplasm cytoplasm cytosol response to virus intermediate filament cytoskeleton defense response to virus defense response to virus positive regulation of MDA-5 signaling pathway positive regulation of RIG-I signaling pathway
1435798_a_at	Sugp2	SURP and G patch domain containing 2	8	70234204, 70234204	BB772209	234373	27	molecular_function nucleic acid binding RNA binding nucleus nucleoplasm nucleoplasm RNA processing mRNA processing biological_process RNA splicing nuclear body
1438577_at	Inpp4b	inositol polyphosphate-4-phosphatase, type II	8	81342561, 81342561	BB376947	234515	33	cytoplasm lipid metabolic process intracellular calcium ion homeostasis lipid binding phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity hydrolase activity phosphatidylinositol bisphosphate phosphatase activity phosphatidylinositol trisphosphate phosphatase activity negative regulation of osteoclast differentiation negative regulation of osteoclast differentiation regulation of nucleocytoplasmic transport regulation of bone remodeling phosphatidylinositol dephosphorylation regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	00562 01100 04070
1424831_at	Cpne2	copine II	8	94533027	BC023348	234577	21	calcium-dependent phospholipid binding calcium-dependent phospholipid binding nucleus cytoplasm plasma membrane plasma membrane membrane metal ion binding cellular response to calcium ion cellular response to calcium ion
1437709_x_at	Ttc13	tetratricopeptide repeat domain 13	8	-124671326	BB492914	234875	13	molecular_function cellular_component biological_process
1435397_at	Zbtb44	zinc finger and BTB domain containing 44	9	31030643	AV146691	235132	23	molecular_function DNA binding nucleus biological_process metal ion binding
1426232_at	Msantd2	Myb/SANT-like DNA-binding domain containing 2	9	37489320	BC024479	235184	19	molecular_function cellular_component biological_process
1428749_at	Dmxl2	Dmx-like 2	9	-54365157	AK018275	235380	38	vacuolar acidification chemical synaptic transmission spermatogenesis brain development sensory perception of smell synaptic vesicle membrane corpus callosum development small GTPase binding cytoplasmic vesicle glucose homeostasis RAVE complex synapse neuronal dense core vesicle
1426556_at	Zfp280d	zinc finger protein 280D	9	72274887	BG066777	235469	23	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus regulation of DNA-templated transcription metal ion binding
1436033_at	Atosa	atos homolog A	9	74952879, 74976110, 74953052	BG276629	235493	16	molecular_function cellular_component nucleus biological_process
1456735_x_at	Pxylp1	2-phosphoxylose phosphatase 1	9	-96823342	BB458645	235534	18	Golgi apparatus Golgi apparatus glycosaminoglycan biosynthetic process glycosaminoglycan biosynthetic process positive regulation of heparan sulfate proteoglycan biosynthetic process membrane dephosphorylation hydrolase activity phosphatase activity phosphatase activity chondroitin sulfate proteoglycan biosynthetic process chondroitin sulfate proteoglycan biosynthetic process
1433520_at	Scap	SREBF chaperone	9	110333355, 110333287	BI412871	235623	80	Golgi membrane response to hypoxia protein binding endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane Golgi apparatus lipid metabolic process immune response steroid metabolic process cholesterol metabolic process lipid binding cholesterol binding membrane regulation of fatty acid metabolic process cytoplasmic vesicle response to insulin SREBP signaling pathway sterol binding SREBP-SCAP complex protein-containing complex regulation of fatty acid biosynthetic process cellular lipid metabolic process protein-containing complex binding regulation of cholesterol biosynthetic process regulation of cholesterol biosynthetic process positive regulation of cholesterol biosynthetic process
1433769_at	Als2cl	ALS2 C-terminal like	9	110880173, 110880321	BM201174	235633	20	GTPase activator activity protein binding cytoplasm cytoplasm endosome organization protein localization endosomal transport small GTPase binding small GTPase binding cytoplasmic vesicle cytoplasmic vesicle identical protein binding regulation of GTPase activity
1434331_at	Ago1	argonaute RISC catalytic subunit 1	4	-126435012, -126435012	BG072783	236511	58	P-body nuclear-transcribed mRNA catabolic process transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II complex binding core promoter sequence-specific DNA binding nucleic acid binding RNA binding RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding protein binding nucleus nucleus cytoplasm cytoplasm cytosol cytosol regulation of translation RNA secondary structure unwinding miRNA metabolic process positive regulation of gene expression RISC complex RISC complex RISC complex negative regulation of angiogenesis regulatory ncRNA-mediated gene silencing pre-miRNA processing pre-miRNA processing regulatory ncRNA-mediated post-transcriptional gene silencing miRNA processing miRNA binding miRNA binding miRNA binding miRNA-mediated gene silencing by inhibition of translation cytoplasmic ribonucleoprotein granule cytoplasmic ribonucleoprotein granule positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II RISC-loading complex RISC complex assembly positive regulation of non-canonical NF-kappaB signal transduction ribonucleoprotein complex
1454714_x_at	Phgdh	3-phosphoglycerate dehydrogenase	3	-98313170	AA561726	236539	78	phosphoglycerate dehydrogenase activity phosphoglycerate dehydrogenase activity phosphoglycerate dehydrogenase activity glutamine metabolic process glycine metabolic process L-serine metabolic process L-serine biosynthetic process threonine metabolic process amino acid biosynthetic process gamma-aminobutyric acid metabolic process regulation of gene expression oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor taurine metabolic process spinal cord development glial cell development neural tube development neurogenesis neuron projection development myelin sheath NAD binding G1 to G0 transition	00260 01100
1454897_at	Slc9a7	solute carrier family 9 (sodium/hydrogen exchanger), member 7	X	-20098850	AV330057	236727	17	endosome Golgi apparatus trans-Golgi network plasma membrane plasma membrane monoatomic ion transport monoatomic cation transport potassium ion transport sodium ion transport regulation of pH antiporter activity sodium:proton antiporter activity sodium:proton antiporter activity potassium:proton antiporter activity potassium:proton antiporter activity membrane intracellular membrane-bounded organelle regulation of intracellular pH recycling endosome recycling endosome membrane transmembrane transport potassium ion transmembrane transport sodium ion import across plasma membrane proton transmembrane transport regulation of Golgi lumen acidification
1454882_at	L3mbtl3	L3MBTL3 histone methyl-lysine binding protein	10	-26274467, -26274467	BB022070	237339	23	chromatin binding chromatin binding protein binding nucleus nucleus nucleus nucleoplasm nucleolus chromatin organization regulation of DNA-templated transcription zinc ion binding myeloid cell differentiation myeloid cell differentiation macrophage differentiation granulocyte differentiation histone binding identical protein binding erythrocyte maturation negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription metal ion binding regulation of DNA methylation-dependent heterochromatin formation methylation-dependent protein binding regulation of ubiquitin-dependent protein catabolic process positive regulation of ubiquitin-dependent protein catabolic process
1444107_at	Mideas	mitotic deacetylase associated SANT domain protein	12	-84149173, -84149173	BB091357	238317	21	histone deacetylase complex transcription corepressor activity nucleoplasm transcription regulator complex regulation of transcription by RNA polymerase II negative regulation of DNA-templated transcription
1421366_at	Clec5a	C-type lectin domain family 5, member a	6	-40574897	NM_021364	23845	31	virus receptor activity virus receptor activity virus receptor activity positive regulation of cytokine production osteoblast development immune system process protein binding cytosol plasma membrane cell surface membrane myeloid cell differentiation carbohydrate binding negative regulation of myeloid cell apoptotic process negative regulation of apoptotic process innate immune response innate immune response innate immune response
1455945_at	Zfp58	zinc finger protein 58	13	-67490166	AV282347	238693	16	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus nucleus regulation of DNA-templated transcription regulation of transcription by RNA polymerase II metal ion binding
1452163_at	Ets1	E26 avian leukemia oncogene 1, 5' domain	9	32696036, 32636240	BB151715	23871	259	transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific transcription corepressor binding DNA-binding transcription activator activity, RNA polymerase II-specific immune system process nucleic acid binding nucleic acid binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm transcription regulator complex cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II positive regulation of cell population proliferation positive regulation of endothelial cell migration positive regulation of gene expression regulation of extracellular matrix disassembly cell differentiation positive regulation of cell migration nuclear receptor coactivator activity PML body organization histone acetyltransferase binding identical protein binding regulation of apoptotic process positive regulation of blood vessel endothelial cell migration sequence-specific DNA binding sequence-specific DNA binding positive regulation of erythrocyte differentiation regulation of angiogenesis positive regulation of angiogenesis negative regulation of cell cycle positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II response to antibiotic cell motility negative regulation of inflammatory response positive regulation of inflammatory response RNA polymerase II-specific DNA-binding transcription factor binding DNA-binding transcription factor binding positive regulation of miRNA transcription positive regulation of leukocyte adhesion to vascular endothelial cell sequence-specific double-stranded DNA binding	04320 05211
1430986_at	Farsb	phenylalanyl-tRNA synthetase, beta subunit	1	-78424744, -78417957	AK012154	23874	35	nucleotide binding magnesium ion binding RNA binding aminoacyl-tRNA ligase activity phenylalanine-tRNA ligase activity phenylalanine-tRNA ligase activity ATP binding cytoplasm translation phenylalanyl-tRNA aminoacylation phenylalanyl-tRNA aminoacylation phenylalanine-tRNA ligase complex phenylalanine-tRNA ligase complex ligase activity metal ion binding protein heterotetramerization	00970
1453851_a_at	Gadd45g	growth arrest and DNA-damage-inducible 45 gamma	13	51846674	AK007410	23882	77	protein binding nucleus nucleus nucleus cytoplasm cytoplasm negative regulation of protein kinase activity apoptotic process multicellular organism development cell differentiation type II interferon production identical protein binding positive regulation of apoptotic process positive regulation of MAPK cascade T-helper 1 cell differentiation positive regulation of JNK cascade regulation of cell cycle regulation of cell cycle positive regulation of cold-induced thermogenesis positive regulation of p38MAPK cascade	04010 04110 04115
1418216_at	Ggt5	gamma-glutamyltransferase 5	10	75589380	NM_011820	23887	23	peptidyltransferase activity leukotriene-C(4) hydrolase leukotriene-C(4) hydrolase leukotriene-C(4) hydrolase plasma membrane plasma membrane plasma membrane proteolysis amino acid metabolic process fatty acid metabolic process glutathione biosynthetic process glutathione catabolic process glutathione catabolic process inflammatory response inflammatory response peptidase activity membrane transferase activity acyltransferase activity hydrolase activity leukotriene biosynthetic process glutathione hydrolase activity glutathione hydrolase activity leukotriene C4 gamma-glutamyl transferase activity leukotriene D4 biosynthetic process leukotriene D4 biosynthetic process leukotriene D4 biosynthetic process leukotriene D4 biosynthetic process	00430 00460 00480 00590 01100
1436395_at	Card6	caspase recruitment domain family, member 6	15	-5097438	BB766747	239319	18	molecular_function cytoplasm regulation of canonical NF-kappaB signal transduction	04621
1457264_at	Phf20l1	PHD finger protein 20-like 1	15	66577571	AV349060	239510	21	molecular_function nucleus regulation of DNA-templated transcription regulation of transcription by RNA polymerase II negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of protein catabolic process NSL complex metal ion binding methylation-dependent protein binding
1453196_a_at	Oasl2	2'-5' oligoadenylate synthetase-like 2	5	114896933	BQ033138	23962	26	nucleotide binding 2'-5'-oligoadenylate synthetase activity 2'-5'-oligoadenylate synthetase activity immune system process RNA binding double-stranded RNA binding double-stranded RNA binding ATP binding nucleoplasm cytosol purine nucleotide biosynthetic process response to virus membrane transferase activity nucleotidyltransferase activity negative regulation of viral genome replication innate immune response metal ion binding defense response to virus defense response to virus regulation of ribonuclease activity interleukin-27-mediated signaling pathway
1436608_at	Pced1b	PC-esterase domain containing 1B	15	97247106	BB457436	239647	13	molecular_function cellular_component biological_process
1449380_at	Pacsin1	protein kinase C and casein kinase substrate in neurons 1	17	27685238, 27655590	BI731319	23969	49	protein binding phospholipid binding phospholipid binding phospholipid binding cytoplasm cytoplasm cytoplasm endosome plasma membrane plasma membrane endocytosis cytoskeleton organization cytoskeleton organization actin filament organization signal transduction cytoskeletal protein binding lipid binding membrane regulation of endocytosis COPI-coated vesicle cytoplasmic vesicle ruffle membrane identical protein binding cell projection neuron projection myelin sheath axon terminus synapse synapse negative regulation of endocytosis perinuclear region of cytoplasm synaptic vesicle endocytosis synaptic vesicle endocytosis neuron development neuron projection morphogenesis neuron projection morphogenesis protein localization to membrane protein localization to plasma membrane plasma membrane tubulation plasma membrane tubulation plasma membrane tubulation photoreceptor ribbon synapse presynapse presynaptic endocytic zone postsynaptic density membrane glutamatergic synapse regulation of postsynaptic neurotransmitter receptor internalization positive regulation of dendrite development positive regulation of dendrite development
1434510_at	Papss2	3'-phosphoadenosine 5'-phosphosulfate synthase 2	19	32620004, 32595714	BF780807	23972	67	sulfate assimilation sulfate assimilation sulfate assimilation nucleotide binding catalytic activity adenylylsulfate kinase activity adenylylsulfate kinase activity adenylylsulfate kinase activity sulfate adenylyltransferase (ATP) activity sulfate adenylyltransferase (ATP) activity ATP binding cytosol blood coagulation metabolic process kinase activity phosphorylation transferase activity nucleotidyltransferase activity hormone metabolic process 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process bone development	00230 00450 00920 01100
1440226_at	Zfp760	zinc finger protein 760	17	21707740	BB088782	240034	14	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II
1424672_at	Dmxl1	Dmx-like 1	18	49832996	BC020141	240283	20	molecular_function vacuolar acidification RAVE complex
1439831_at	Iigp1c	interferon inducible GTPase 1C	18	60212076	AW111920	240327	13	GTPase activity endoplasmic reticulum membrane defense response cellular response to interferon-beta cellular response to interferon-beta
1456126_at	Malt1	MALT1 paracaspase	18	65430989	BB485735	240354	110	fibrillar center B-1 B cell differentiation protease binding polkadots immune system process positive regulation of T cell cytokine production endopeptidase activity cysteine-type endopeptidase activity ubiquitin-protein transferase activity protein binding nucleus cytoplasm cytosol cytosol cytosol proteolysis proteolysis apoptotic process canonical NF-kappaB signal transduction activation of NF-kappaB-inducing kinase activity peptidase activity response to fungus hydrolase activity kinase activator activity lipopolysaccharide-mediated signaling pathway CBM complex positive regulation of interleukin-1 beta production positive regulation of interleukin-2 production protein-containing complex small molecule binding T cell proliferation B cell activation B cell activation identical protein binding regulation of apoptotic process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process protein self-association innate immune response innate immune response T cell receptor signaling pathway T cell receptor signaling pathway T cell receptor signaling pathway regulation of T cell receptor signaling pathway positive regulation of T cell activation positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity nuclear export proteolysis involved in protein catabolic process cellular response to lipopolysaccharide positive regulation of T-helper 17 cell differentiation	04660 04662
1421923_at	Sh3bp5	SH3-domain binding protein 5 (BTK-associated)	14	-31372613, -31372613	BQ179335	24056	30	protein kinase inhibitor activity protein kinase inhibitor activity guanyl-nucleotide exchange factor activity nucleoplasm cytoplasm cytoplasm mitochondrion negative regulation of protein kinase activity membrane nuclear body SH3 domain binding cytoplasmic vesicle membrane cytoplasmic vesicle intracellular signal transduction intracellular signal transduction
1449163_at	Sigirr	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	7	-141091174	NM_023059	24058	68	negative regulation of cytokine-mediated signaling pathway acute-phase response signal transduction membrane negative regulation of chemokine production negative regulation of DNA-binding transcription factor activity
1450024_at	Sufu	SUFU negative regulator of hedgehog signaling	19	46396895	AJ308624	24069	125	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II neural tube closure heart looping ventricular septum development protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm cytoplasm cytosol cilium regulation of DNA-templated transcription smoothened signaling pathway multicellular organism development determination of left/right symmetry beta-catenin binding transcription factor binding transcription factor binding protein kinase binding spinal cord dorsal/ventral patterning smoothened signaling pathway involved in ventral spinal cord interneuron specification smoothened signaling pathway involved in spinal cord motor neuron cell fate specification aorta development cytoplasmic sequestering of transcription factor cytoplasmic sequestering of transcription factor skin development negative regulation of smoothened signaling pathway negative regulation of smoothened signaling pathway coronary vasculature development GLI-SUFU complex negative regulation of ubiquitin-dependent protein catabolic process	04340 05200 05217
1438687_at	Lax1	lymphocyte transmembrane adaptor 1	1	-133679028, -133679028	BE630983	240754	17	adaptive immune response immune system process immunoglobulin production Golgi apparatus cytosol plasma membrane plasma membrane immune response immune response membrane protein kinase binding intracellular signal transduction intracellular signal transduction B cell activation SH2 domain binding negative regulation of MAP kinase activity lymphocyte activation lymphocyte activation antigen receptor-mediated signaling pathway antigen receptor-mediated signaling pathway negative regulation of T cell activation negative regulation of T cell activation regulation of lymphocyte activation
1419132_at	Tlr2	toll-like receptor 2	3	-83836271	NM_011905	24088	1959	lipopolysaccharide binding amyloid-beta binding amyloid-beta binding microglial cell activation positive regulation of cytokine production toll-like receptor signaling pathway toll-like receptor signaling pathway response to molecule of fungal origin immune system process positive regulation of leukocyte migration regulation of dendritic cell cytokine production cell surface pattern recognition receptor signaling pathway MyD88-dependent toll-like receptor signaling pathway transmembrane signaling receptor activity protein binding cytoplasm Golgi apparatus plasma membrane plasma membrane leukotriene metabolic process nitric oxide biosynthetic process defense response inflammatory response inflammatory response immune response signal transduction I-kappaB phosphorylation learning negative regulation of cell population proliferation response to bacterium external side of plasma membrane cell surface positive regulation of gene expression macrophage cytokine production macrophage cytokine production microglia development membrane positive regulation of Wnt signaling pathway negative regulation of actin filament polymerization cytoplasmic vesicle central nervous system myelin formation response to bacterial lipoprotein response to peptidoglycan chemokine production interleukin-17 production interleukin-6 production interleukin-6 production tumor necrosis factor production negative regulation of interleukin-12 production negative regulation of interleukin-17 production positive regulation of chemokine production positive regulation of chemokine production positive regulation of interferon-beta production positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-18 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production toll-like receptor 2 signaling pathway Toll-like receptor binding Toll-like receptor 1-Toll-like receptor 2 protein complex Toll-like receptor 2-Toll-like receptor 6 protein complex Toll-like receptor 2-Toll-like receptor 6 protein complex signaling receptor activity toll-like receptor TLR6:TLR2 signaling pathway pattern recognition receptor activity pattern recognition receptor activity detection of triacyl bacterial lipopeptide detection of diacyl bacterial lipopeptide triacyl lipopeptide binding triacyl lipopeptide binding triacyl lipopeptide binding diacyl lipopeptide binding identical protein binding peptidoglycan binding cell projection receptor complex cell body protein-containing complex binding protein-containing complex binding innate immune response membrane raft positive regulation of nitric oxide biosynthetic process positive regulation of transcription by RNA polymerase II nitric oxide metabolic process positive regulation of oligodendrocyte differentiation positive regulation of inflammatory response positive regulation of inflammatory response negative regulation of phagocytosis negative regulation of phagocytosis defense response to Gram-positive bacterium defense response to Gram-positive bacterium leukocyte migration positive regulation of NF-kappaB transcription factor activity positive regulation of nitric-oxide synthase biosynthetic process negative regulation of synapse assembly positive regulation of macrophage cytokine production positive regulation of macrophage cytokine production ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade response to fatty acid lipoteichoic acid binding cellular response to bacterial lipopeptide cellular response to bacterial lipopeptide cellular response to lipoteichoic acid cellular response to lipoteichoic acid cellular response to peptidoglycan cellular response to type II interferon lipopeptide binding cellular response to diacyl bacterial lipopeptide cellular response to triacyl bacterial lipopeptide xenophagy positive regulation of non-canonical NF-kappaB signal transduction positive regulation of intracellular signal transduction positive regulation of neutrophil migration positive regulation of cellular response to macrophage colony-stimulating factor stimulus positive regulation of xenophagy positive regulation of matrix metallopeptidase secretion neutrophil migration	04145 04620 05140 05142 05144 05145 05146 05323
1452960_at	Scyl3	SCY1-like 3 (S. cerevisiae)	1	163929764, 163929099	BB274851	240880	17	Golgi membrane protein kinase activity protein binding ATP binding cytoplasm endoplasmic reticulum Golgi apparatus Golgi apparatus cytosol protein phosphorylation inflammatory response protein localization spinal cord motor neuron differentiation lamellipodium identical protein binding cell projection neuron development
1436317_at	Pgap1	post-GPI attachment to proteins 1	1	-54472999	BM115569	241062	27	endoplasmic reticulum endoplasmic reticulum GPI anchor metabolic process GPI anchor biosynthetic process endoplasmic reticulum to Golgi vesicle-mediated transport sensory perception of sound embryonic pattern specification embryonic pattern specification anterior/posterior axis specification anterior/posterior axis specification protein transport membrane hydrolase activity hydrolase activity, acting on ester bonds forebrain regionalization forebrain regionalization phosphatidylinositol deacylase activity phosphatidylinositol deacylase activity head development head development positive regulation of ER to Golgi vesicle-mediated transport	00563 01100
1418191_at	Usp18	ubiquitin specific peptidase 18	6	121245905	NM_011909	24110	78	cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity protein binding nucleus nucleus cytosol cytosol proteolysis peptidase activity cysteine-type peptidase activity response to bacterium protein deubiquitination protein deubiquitination hydrolase activity ISG15-specific peptidase activity ISG15-specific peptidase activity response to stilbenoid intracellular membrane-bounded organelle molecular adaptor activity
1456147_at	St8sia6	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6	2	-13654935	BB486599	241230	22	ganglioside biosynthetic process blastocyst hatching alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity Golgi apparatus protein glycosylation protein glycosylation N-glycan processing protein O-linked glycosylation lipid metabolic process sialyltransferase activity glycoprotein metabolic process glycolipid biosynthetic process oligosaccharide metabolic process oligosaccharide metabolic process membrane carbohydrate biosynthetic process transferase activity glycosyltransferase activity
1450777_at	Xrn2	5'-3' exoribonuclease 2	2	147012998	NM_011917	24128	37	3'-5'-RNA exonuclease activity nuclear-transcribed mRNA catabolic process transcription termination site sequence-specific DNA binding nucleic acid binding DNA binding RNA binding nuclease activity exonuclease activity 5'-3' RNA exonuclease activity 5'-3' RNA exonuclease activity protein binding nucleus nucleus nucleoplasm nucleolus nucleobase-containing compound metabolic process DNA repair DNA recombination DNA-templated transcription termination termination of RNA polymerase II transcription mRNA processing microtubule-based process spermatogenesis 5'-3' exonuclease activity RNA metabolic process aggresome hydrolase activity identical protein binding metal ion binding	03008 03018
1433657_at	Fam78a	family with sequence similarity 78, member A	2	-32050054, -32050054, -32050054, -32066884	BI111848	241303	11	molecular_function cellular_component biological_process
1449414_at	Zfp53	zinc finger protein 53	17	21488987	NM_013843	24132	19	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific protein binding nucleus regulation of transcription by RNA polymerase II
1448760_at	Zfp68	zinc finger protein 68	5	-138603651	NM_013844	24135	29	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II
1434418_at	Cers6	ceramide synthase 6	2	68861440	BQ176664	241447	43	DNA binding protein binding endoplasmic reticulum lipid metabolic process inflammatory response membrane transferase activity sphingolipid biosynthetic process ceramide biosynthetic process ceramide biosynthetic process ceramide biosynthetic process ceramide biosynthetic process sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity positive regulation of oligodendrocyte apoptotic process
1447788_s_at	Tspyl3	TSPY-like 3	2	-153222369	BB308532	241732	10	chromatin molecular_function chromatin binding nucleus biological_process histone binding
1456328_at	Bank1	B cell scaffold protein with ankyrin repeats 1	3	-136053363	AI451642	242248	24	MAPK cascade protease binding signaling receptor binding signaling receptor binding protein binding signal transduction response to bacterium interleukin-6 production negative regulation of interleukin-6 production signaling adaptor activity B cell activation B cell activation phospholipase binding positive regulation of MAPK cascade phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of translational initiation perinuclear region of cytoplasm positive regulation of peptidyl-tyrosine phosphorylation negative regulation of B cell activation negative regulation of B cell activation negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction protein tyrosine kinase binding protein tyrosine kinase binding
1433441_at	Fbxl5	F-box and leucine-rich repeat protein 5	5	-43757748, -43744617	BQ173911	242960	33	iron ion binding nucleus cytoplasm intracellular iron ion homeostasis protein ubiquitination SCF ubiquitin ligase complex SCF ubiquitin ligase complex protein catabolic process SCF-dependent proteasomal ubiquitin-dependent protein catabolic process SCF-dependent proteasomal ubiquitin-dependent protein catabolic process positive regulation of protein catabolic process metal ion binding perinuclear region of cytoplasm iron-sulfur cluster binding multicellular organismal-level iron ion homeostasis multicellular organismal-level iron ion homeostasis
1455026_at	Sbno1	strawberry notch 1	5	-124368701, -124368701	BE947961	243272	25	nucleus regulation of DNA-templated transcription regulation of DNA-templated transcription chromatin DNA binding histone binding
1456061_at	Gimap8	GTPase, IMAP family member 8	6	48647360, 48647233, 48647360	BM243674	243374	14	nucleotide binding GTP binding cytoplasm mitochondrion endoplasmic reticulum endoplasmic reticulum Golgi apparatus regulation of T cell apoptotic process
1452463_x_at	Igk	immunoglobulin kappa chain complex	6		BG966217	243469	218
1426774_at	Parp12	poly (ADP-ribose) polymerase family, member 12	6	-39086411	BM227980	243771	28	NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity cellular_component nucleus nucleus transferase activity glycosyltransferase activity nucleotidyltransferase activity metal ion binding protein auto-ADP-ribosylation NAD+-protein ADP-ribosyltransferase activity NAD+-protein ADP-ribosyltransferase activity
1435955_at	Siglecg	sialic acid binding Ig-like lectin G	7	43408279, 43408238	BE447170	243958	38	hematopoietic progenitor cell differentiation adaptive immune response immune system process negative regulation of immunoglobulin production protein binding plasma membrane plasma membrane cell adhesion cell adhesion membrane phosphatase binding carbohydrate binding regulation of B cell proliferation regulation of B cell proliferation sialic acid binding sialic acid binding SH2 domain binding innate immune response regulation of immune response negative regulation of calcium-mediated signaling negative regulation of inflammatory response to wounding
1436590_at	Ppp1r3b	protein phosphatase 1, regulatory subunit 3B	8	35375758, 35376661	BG071940	244416	21	protein phosphatase type 1 complex protein phosphatase type 1 complex phosphoprotein phosphatase activity carbohydrate metabolic process glycogen metabolic process regulation of glycogen biosynthetic process regulation of glycogen biosynthetic process regulation of glycogen catabolic process protein phosphatase 1 binding protein phosphatase regulator activity enzyme binding glycogen granule [phosphorylase] phosphatase activity glycogen binding	04910
1442434_at	Prag1	PEAK1 related kinase activating pseudokinase 1	8	36094827	BM195829	244418	23	protein kinase activity protein kinase activity protein binding ATP binding nucleus cytoplasm focal adhesion protein phosphorylation protein phosphorylation regulation of cell shape regulation of Notch signaling pathway negative regulation of neuron projection development cell migration positive regulation of Rho protein signal transduction identical protein binding anchoring junction regulation of cell motility
1456485_at	Npat	nuclear protein in the AT region	9	53537046	BM207451	244879	31	in utero embryonic development transcription coregulator activity transcription coactivator activity transcription corepressor activity nucleus nucleus nucleoplasm cytoplasm cell cycle Cajal body cell cycle G1/S phase transition positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II Gemini of coiled bodies
1427197_at	Atr	ataxia telangiectasia and Rad3 related	9	95857596	AF236887	245000	150	DNA damage checkpoint signaling DNA damage checkpoint signaling DNA damage checkpoint signaling nucleotide binding telomere maintenance male germ cell nucleus XY body DNA binding protein kinase activity protein kinase activity protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding nucleus nucleus nucleus nuclear envelope nucleoplasm nucleoplasm chromosome Golgi apparatus nucleobase-containing compound metabolic process DNA repair double-strand break repair protein phosphorylation protein phosphorylation DNA damage response DNA damage response embryo implantation negative regulation of DNA replication response to mechanical stimulus kinase activity phosphorylation PML body transferase activity peptidyl-serine phosphorylation replication fork processing positive regulation of telomere maintenance via telomerase MutLalpha complex binding MutSalpha complex binding cellular response to UV histone H2AXS139 kinase activity regulation of protein binding positive regulation of DNA damage response, signal transduction by p53 class mediator protein autophosphorylation nuclear membrane disassembly chromosome organization protein localization to chromosome, telomeric region ATR-ATRIP complex ATR-ATRIP complex cellular response to gamma radiation replicative senescence site of DNA damage establishment of RNA localization to telomere positive regulation of telomerase catalytic core complex assembly regulation of double-strand break repair	04110 04115
1423411_at	Rbm47	RNA binding motif protein 47	5	-66016548, -66016548, -66016548	BI099836	245945	30	regulation of alternative mRNA splicing, via spliceosome hematopoietic progenitor cell differentiation nucleic acid binding RNA binding RNA binding mRNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding protein binding nucleus nucleus nucleus cytoplasm mRNA processing RNA splicing cytidine to uridine editing cytidine to uridine editing cytidine to uridine editing enzyme binding apolipoprotein B mRNA editing enzyme complex positive regulation of interleukin-10 production positive regulation of type I interferon-mediated signaling pathway 3'-UTR-mediated mRNA stabilization 3'-UTR-mediated mRNA stabilization enzyme-substrate adaptor activity enzyme-substrate adaptor activity
1433811_at	Mllt6	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6	11	97663411	BG245272	246198	28	renal system process nucleus chromatin organization regulation of transcription by RNA polymerase II positive regulation of sodium ion transport nucleosome binding nucleosome binding negative regulation of urine volume renal sodium excretion renal potassium excretion histone binding histone binding positive regulation of transcription by RNA polymerase II renal water absorption
1425225_at	Fcgr4	Fc receptor, IgG, low affinity IV	1	171018925	BC027310	246256	55	antibody-dependent cellular cytotoxicity immune system process dendritic cell antigen processing and presentation extracellular space plasma membrane plasma membrane cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane cell surface cell surface membrane IgE receptor activity IgG receptor activity IgG receptor activity low-affinity IgG receptor activity IgE binding IgG binding Fc-gamma receptor III complex GPI anchor binding perforin production neutrophil activation natural killer cell degranulation positive regulation of bone resorption cellular response to lipopolysaccharide immune receptor activity immune receptor activity Fc receptor-mediated immune complex endocytosis	04145 04380 04650 05140 05150 05322
1435264_at	Emilin2	elastin microfibril interfacer 2	17	-71252171, -71252171	BB811788	246707	29	extracellular region collagen trimer cell adhesion extracellular matrix constituent conferring elasticity positive regulation of blood coagulation negative regulation of cell migration positive regulation of apoptotic process positive regulation of angiogenesis collagen-containing extracellular matrix collagen-containing extracellular matrix positive regulation of defense response to bacterium positive regulation of platelet aggregation
1425374_at	Oas3	2'-5' oligoadenylate synthetase 3	5	-120753097	AB067534	246727	20	nucleotide binding 2'-5'-oligoadenylate synthetase activity 2'-5'-oligoadenylate synthetase activity 2'-5'-oligoadenylate synthetase activity immune system process RNA binding double-stranded RNA binding double-stranded RNA binding double-stranded RNA binding ATP binding nucleus nucleoplasm nucleoplasm cytoplasm cytosol cytosol plasma membrane response to virus membrane transferase activity nucleotidyltransferase activity positive regulation of interferon-beta production positive regulation of tumor necrosis factor production negative regulation of chemokine (C-X-C motif) ligand 9 production RIG-I signaling pathway MDA-5 signaling pathway defense response to bacterium negative regulation of viral genome replication negative regulation of viral genome replication innate immune response metal ion binding defense response to virus defense response to virus negative regulation of type I interferon-mediated signaling pathway regulation of ribonuclease activity regulation of ribonuclease activity positive regulation of monocyte chemotactic protein-1 production negative regulation of chemokine (C-C motif) ligand 5 production negative regulation of IP-10 production negative regulation of chemokine (C-X-C motif) ligand 2 production	05160
1425065_at	Oas2	2'-5' oligoadenylate synthetase 2	5	-120730332	AB067535	246728	29	nucleotide binding 2'-5'-oligoadenylate synthetase activity 2'-5'-oligoadenylate synthetase activity 2'-5'-oligoadenylate synthetase activity immune system process RNA binding double-stranded RNA binding double-stranded RNA binding double-stranded RNA binding ATP binding nucleoplasm cytoplasm cytosol RNA catabolic process response to virus response to bacterium membrane transferase activity nucleotidyltransferase activity positive regulation of interferon-beta production positive regulation of tumor necrosis factor production defense response to bacterium negative regulation of viral genome replication innate immune response metal ion binding perinuclear region of cytoplasm defense response to virus defense response to virus type I interferon-mediated signaling pathway regulation of ribonuclease activity interleukin-27-mediated signaling pathway interleukin-27-mediated signaling pathway regulation of lactation	05160
1427994_at	Cd300lf	CD300 molecule like family member F	11	-115116213	BM230330	246746	57	virus receptor activity phosphatidylserine binding immune system process transmembrane signaling receptor activity interleukin-4 receptor binding protein binding plasma membrane plasma membrane lipid binding membrane osteoclast differentiation negative regulation of mast cell activation negative regulation of mast cell activation negative regulation of MyD88-dependent toll-like receptor signaling pathway TRIF-dependent toll-like receptor signaling pathway interleukin-13-mediated signaling pathway identical protein binding ceramide binding ceramide binding positive regulation of interleukin-4-mediated signaling pathway negative regulation of apoptotic cell clearance positive regulation of apoptotic cell clearance positive regulation of apoptotic cell clearance
1455735_at	Ap1s3	adaptor-related protein complex AP-1, sigma 3	1	-79606875	AW259574	252903	20	molecular_function lysosomal membrane early endosome Golgi apparatus clathrin-coated pit protein targeting intracellular protein transport protein transport membrane vesicle-mediated transport vesicle-mediated transport membrane coat AP-1 adaptor complex cytoplasmic vesicle trans-Golgi network membrane clathrin adaptor activity intracellular membrane-bounded organelle intracellular membrane-bounded organelle platelet dense granule organization melanosome assembly	04142
1419722_at	Klk8	kallikrein related-peptidase 8	7	43797576	NM_008940	259277	54	serine-type endopeptidase activity serine-type endopeptidase activity extracellular region extracellular space cytoplasm cytoplasm proteolysis memory memory peptidase activity peptidase activity serine-type peptidase activity response to wounding hydrolase activity secretory granule keratinocyte proliferation neuron projection morphogenesis neuron projection morphogenesis regulation of synapse organization synapse organization serine protease inhibitor complex
1427711_a_at	Ceacam1	CEA cell adhesion molecule 1	7	-25461701	X15351	26365	158	regulation of cell growth blood vessel development negative regulation of cytokine production regulation of immune system process negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target actin binding granulocyte colony-stimulating factor receptor binding protein binding calmodulin binding extracellular space plasma membrane plasma membrane plasma membrane cell-cell junction adherens junction negative regulation of protein kinase activity cell adhesion signal transduction external side of plasma membrane basal plasma membrane cell surface cell surface cell surface regulation of endothelial cell migration bile acid transmembrane transporter activity bile acid and bile salt transport membrane basolateral plasma membrane apical plasma membrane lateral plasma membrane kinase binding protein kinase binding protein phosphatase binding cell junction negative regulation of granulocyte differentiation filamin binding cytoplasmic vesicle negative regulation of interleukin-1 production cellular response to insulin stimulus GPI anchor binding Toll-like receptor binding common myeloid progenitor cell proliferation insulin receptor internalization granulocyte colony-stimulating factor signaling pathway regulation of epidermal growth factor receptor signaling pathway regulation of epidermal growth factor receptor signaling pathway T cell receptor complex negative regulation of T cell proliferation identical protein binding protein homodimerization activity cell projection negative regulation of vascular permeability positive regulation of MAP kinase activity protein-containing complex binding cell-cell junction organization regulation of endothelial cell differentiation negative regulation of osteoclast differentiation negative regulation of fatty acid biosynthetic process negative regulation of bone resorption protein heterodimerization activity protein dimerization activity negative regulation of lipid biosynthetic process regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction ciliary membrane regulation of blood vessel remodeling transforming growth factor beta ligand-receptor complex anchoring junction regulation of ERK1 and ERK2 cascade negative regulation of platelet aggregation cell-cell adhesion via plasma-membrane adhesion molecules insulin catabolic process insulin catabolic process regulation of homophilic cell adhesion positive regulation of homophilic cell adhesion regulation of sprouting angiogenesis protein tyrosine kinase binding protein tyrosine kinase binding protein tyrosine kinase binding negative regulation of hepatocyte proliferation negative regulation of hepatocyte proliferation positive regulation of vasculogenesis
1417074_at	Ceacam10	CEA cell adhesion molecule 10	7	24777203, 24777166	NM_007675	26366	20	regulation of immune system process plasma membrane signal transduction cell surface protein tyrosine kinase binding
1419515_at	Fgd2	FYVE, RhoGEF and PH domain containing 2	17	29360913	NM_013710	26382	25	ruffle guanyl-nucleotide exchange factor activity nucleus cytoplasm cytoplasm endosome early endosome cytoskeleton plasma membrane cytoskeleton organization membrane cell projection positive regulation of JUN kinase activity filopodium assembly metal ion binding phosphatidylinositol phosphate binding
1457666_s_at	Ifi202b	interferon activated gene 202B	1	-173962568	AV229143	26388	54	cellular response to interferon-beta	04623
1424850_at	Map3k1	mitogen-activated protein kinase kinase kinase 1	13	-111746427	L13103	26401	113	MAPK cascade nucleotide binding protein polyubiquitination morphogenesis of an epithelial sheet epithelial cell morphogenesis protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity JUN kinase kinase kinase activity JUN kinase kinase kinase activity MAP kinase kinase activity MAP kinase kinase kinase activity ubiquitin-protein transferase activity protein binding ATP binding cytoplasm cytosol protein phosphorylation ubiquitin-dependent protein catabolic process transforming growth factor beta receptor signaling pathway JNK cascade cytoskeletal protein binding zinc ion binding JUN kinase binding apoptotic mitochondrial changes kinase activity phosphorylation transferase activity protein kinase binding cell junction regulation of cell migration positive regulation of actin filament polymerization mitogen-activated protein kinase kinase binding filamentous actin negative regulation of actin filament bundle assembly wound healing camera-type eye development positive regulation of apoptotic process positive regulation of MAPK cascade positive regulation of JUN kinase activity protein-containing complex binding positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of JNK cascade sphingolipid binding metal ion binding positive regulation of viral transcription mitogen-activated protein kinase binding eyelid development in camera-type eye positive regulation of canonical Wnt signaling pathway	04010 04120 04622 04722 04912
1455597_at	Map3k2	mitogen-activated protein kinase kinase kinase 2	18	32163088	AV024458	26405	52	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding nucleus nucleoplasm cytoplasm cytoplasm cytosol protein phosphorylation kinase activity phosphorylation transferase activity protein kinase binding intracellular signal transduction metal ion binding	04010 04540 04912
1459800_s_at	Map3k4	mitogen-activated protein kinase kinase kinase 4	17	-12227620, -12227620	AV079128	26407	82	MAPK cascade nucleotide binding placenta development protein kinase activity protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding cytoplasm cytoplasm protein phosphorylation response to UV-C regulation of gene expression kinase activity phosphorylation transferase activity male germ-line sex determination positive regulation of telomere maintenance via telomerase intracellular signal transduction positive regulation of JUN kinase activity positive regulation of JUN kinase activity positive regulation of JUN kinase activity metal ion binding determination of dorsal identity positive regulation of telomerase activity chorionic trophoblast cell differentiation positive regulation of p38MAPK cascade positive regulation of telomere capping	04010 04912
1439323_a_at	Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	7	28982049, 28982853	BB546619	26411	41	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding ATP binding cytoplasm protein phosphorylation protein phosphorylation protein phosphorylation JNK cascade cell population proliferation MAP kinase kinase kinase kinase activity MAP kinase kinase kinase kinase activity kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation intracellular signal transduction intracellular signal transduction positive regulation of MAPK cascade protein autophosphorylation cellular response to phorbol 13-acetate 12-myristate	04010
1434833_at	Map4k2	mitogen-activated protein kinase kinase kinase kinase 2	19	6341159	BB667222	26412	17	nucleotide binding immune system process protein kinase activity protein serine/threonine kinase activity ATP binding cytoplasm cytoplasm Golgi apparatus plasma membrane protein phosphorylation protein phosphorylation vesicle targeting MAP kinase kinase kinase kinase activity MAP kinase kinase kinase kinase activity membrane kinase activity phosphorylation transferase activity mitogen-activated protein kinase kinase kinase binding intracellular signal transduction intracellular signal transduction positive regulation of JUN kinase activity innate immune response positive regulation of JNK cascade	04010
1448871_at	Mapk13	mitogen-activated protein kinase 13	17	28769316	NM_011950	26415	68	MAPK cascade nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity MAP kinase activity ATP binding nucleus nucleoplasm cytoplasm protein phosphorylation response to osmotic stress cell cycle kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation positive regulation of interleukin-6 production cellular response to UV intracellular signal transduction stress-activated MAPK cascade cellular response to hydrogen peroxide cellular response to interleukin-1 cellular response to sorbitol cellular response to anisomycin cellular response to sodium arsenite	04010 04370 04380 04620 04621 04622 04660 04664 04670 04722 04912 04914 05014 05140 05142 05145 05160
1419165_at	Zfp260	zinc finger protein 260	7	30095075	D45210	26466	24	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus nucleus nucleoplasm cytosol regulation of transcription by RNA polymerase II multicellular organism development metal ion binding
1452261_at	Shprh	SNF2 histone linker PHD RING helicase	10	11149429, 11149429, 11149429	BC006883	268281	24	nucleotide binding protein polyubiquitination protein polyubiquitination nucleosome DNA binding helicase activity ubiquitin-protein transferase activity ATP binding cellular_component DNA repair nucleosome assembly DNA damage response DNA damage response transferase activity hydrolase activity ubiquitin protein ligase binding metal ion binding ubiquitin protein ligase activity ubiquitin protein ligase activity ATP-dependent chromatin remodeler activity
1427417_at	Scml4	Scm polycomb group protein like 4	10	42860511, 42860511	BB212066	268297	14	chromatin binding nucleus nucleus histone binding negative regulation of DNA-templated transcription
1446715_at	Abca13	ATP-binding cassette, sub-family A member 13	11	9191941	BB503961	268379	22	nucleotide binding lipid transporter activity ATP binding lipid transport lipid transport membrane ATP hydrolysis activity cytoplasmic vesicle positive regulation of cholesterol transport positive regulation of cholesterol transport ceramide transport ATPase-coupled transmembrane transporter activity intracellular membrane-bounded organelle transmembrane transport intracellular vesicle intracellular vesicle ABC-type transporter activity positive regulation of synaptic vesicle endocytosis	02010
1458148_at	Nlrc3	NLR family, CARD domain containing 3	16	-3945006	BB466171	268857	31	nucleotide binding protein binding ATP binding cytoplasm cytoplasm cytosol cytosol canonical NF-kappaB signal transduction canonical NF-kappaB signal transduction canonical NF-kappaB signal transduction regulation of protein ubiquitination regulation of protein ubiquitination negative regulation of NF-kappaB transcription factor activity negative regulation of NF-kappaB transcription factor activity response to lipopolysaccharide negative regulation of interferon-alpha production negative regulation of interferon-beta production negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production negative regulation of interleukin-6 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production negative regulation of tumor necrosis factor production centriolar satellite intracellular signal transduction phosphatidylinositol 3-kinase regulatory subunit binding T cell activation negative regulation of canonical NF-kappaB signal transduction negative regulation of canonical NF-kappaB signal transduction negative regulation of canonical NF-kappaB signal transduction negative regulation of canonical NF-kappaB signal transduction negative regulation of canonical NF-kappaB signal transduction intracellular membrane-bounded organelle negative regulation of innate immune response negative regulation of fibroblast proliferation perinuclear region of cytoplasm negative regulation of epithelial cell proliferation negative regulation of inflammatory response negative regulation of inflammatory response negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction molecular function inhibitor activity negative regulation of cytokine production involved in inflammatory response negative regulation of NLRP3 inflammasome complex assembly negative regulation of non-canonical NF-kappaB signal transduction
1422013_at	Clec4a2	C-type lectin domain family 4, member a2	6	123122689, 123123315	NM_011999	26888	32	adaptive immune response immune system process calcium ion binding mannose binding plasma membrane external side of plasma membrane membrane carbohydrate binding carbohydrate binding carbohydrate binding innate immune response metal ion binding antifungal innate immune response
1442339_at	Stfa2l1	stefin A2 like 1	16	36156810	BB667930	268885	10	cornified envelope protease binding cysteine-type endopeptidase inhibitor activity cysteine-type endopeptidase inhibitor activity extracellular space nucleoplasm cytoplasm cytosol cytosol negative regulation of peptidase activity peptide cross-linking keratinocyte differentiation negative regulation of proteolysis cell-cell adhesion peptidase inhibitor complex
1455745_at	Cln8	CLN8 transmembrane ER and ERGIC protein	8	14888535	BM249363	26889	87	protein binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment phospholipid metabolic process phospholipid metabolic process phospholipid metabolic process ceramide metabolic process apoptotic process mitochondrial membrane organization lysosome organization nervous system development nervous system development visual perception adult walking behavior cholesterol metabolic process associative learning adult locomotory behavior regulation of cell size macromolecule catabolic process membrane protein metabolic process spinal cord motor neuron differentiation somatic motor neuron differentiation protein catabolic process social behavior negative regulation of neuron apoptotic process photoreceptor cell maintenance musculoskeletal movement neuromuscular process controlling posture neuromuscular process controlling balance negative regulation of transferase activity neuron apoptotic process glutamate reuptake lipid homeostasis retina development in camera-type eye neurofilament cytoskeleton organization ceramide binding ceramide binding retinal rod cell apoptotic process
1435641_at	Mgat4a	mannoside acetylglucosaminyltransferase 4, isoenzyme A	1	-37439339, -37439339	BB109391	269181	21	extracellular region endoplasmic reticulum endoplasmic reticulum-Golgi intermediate compartment Golgi apparatus Golgi stack protein glycosylation protein N-linked glycosylation protein N-linked glycosylation N-glycan processing acetylglucosaminyltransferase activity acetylglucosaminyltransferase activity alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity membrane transferase activity glycosyltransferase activity metal ion binding	00510 01100
1433794_at	Setx	senataxin	2	29124991	BM211942	269254	43	MAPK cascade nucleotide binding nuclear chromosome chromosome, telomeric region transcription termination site sequence-specific DNA binding transcription termination site sequence-specific DNA binding RNA binding helicase activity protein binding ATP binding nucleus nucleoplasm chromosome cytoplasm DNA repair double-strand break repair DNA recombination DNA-templated transcription termination termination of RNA polymerase II transcription termination of RNA polymerase II transcription mRNA splice site recognition DNA damage response spermatogenesis nervous system development circadian rhythm fibroblast growth factor receptor signaling pathway positive regulation of neuron projection development nuclear body nuclear body hydrolase activity cell differentiation axon growth cone positive regulation of RNA splicing cellular response to oxidative stress identical protein binding cell projection negative regulation of apoptotic process phosphatidylinositol 3-kinase/protein kinase B signal transduction cellular response to fibroblast growth factor stimulus intercellular bridge positive regulation of transcription by RNA polymerase II rhythmic process positive regulation of termination of DNA-templated transcription cellular response to hydrogen peroxide cellular response to retinoic acid positive regulation of DNA-templated transcription initiation positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled
1435655_at	Rpl12	ribosomal protein L12	2	32961711	BG807990	269261	38	cytoplasmic translation RNA binding structural constituent of ribosome structural constituent of ribosome protein binding nucleus nucleolus cytoplasm cytosol ribosome translation translation postsynaptic density cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome synapse synapse synapse large ribosomal subunit rRNA binding large ribosomal subunit rRNA binding presynapse postsynapse translation at presynapse translation at postsynapse ribonucleoprotein complex	03010
1456038_at	Fbxl4	F-box and leucine-rich repeat protein 4	4	22357542	BB003709	269514	20	autophagy of mitochondrion autophagy of mitochondrion nucleus cytoplasm mitochondrion mitochondrial intermembrane space nuclear speck SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
1439464_s_at	Tex10	testis expressed gene 10	4	-48430857	AV278060	269536	25	nucleus nucleus nucleoplasm cytoplasm mitochondrion MLL1 complex MLL1 complex
1435004_at	Pank4	pantothenate kinase 4	4	154964122	BM119773	269614	25	nucleotide binding pantothenate kinase activity pantothenate kinase activity ATP binding extracellular space nucleus cytoplasm cytosol cytosol cytosol coenzyme A biosynthetic process coenzyme A biosynthetic process coenzyme A catabolic process coenzyme A catabolic process hydrolase activity phosphatase activity metal ion binding	00770 01100
1434935_at	Aak1	AP2 associated kinase 1	6	86849504, 86849283, 86849504	BG067888	269774	36	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity Notch binding ATP binding cytosol plasma membrane clathrin-coated pit protein phosphorylation protein phosphorylation endocytosis membrane kinase activity phosphorylation transferase activity cell leading edge regulation of protein localization AP-2 adaptor complex binding AP-2 adaptor complex binding cell projection terminal bouton intracellular membrane-bounded organelle calyx of Held synapse positive regulation of Notch signaling pathway protein stabilization clathrin complex presynapse presynapse presynapse presynaptic endocytosis presynaptic endocytosis presynaptic endocytosis regulation of clathrin-dependent endocytosis regulation of clathrin-dependent endocytosis
1456411_at	Rccd1	RCC1 domain containing 1	7	-80316615	BM218704	269955	14	molecular_function chromosome cytosol plasma membrane chromatin organization biological_process
1434945_at	Lpcat2	lysophosphatidylcholine acyltransferase 2	8	92855332	AW743924	270084	26	1-acylglycerol-3-phosphate O-acyltransferase activity calcium ion binding endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus Golgi stack lipid droplet plasma membrane lipid metabolic process platelet activating factor biosynthetic process O-acyltransferase activity phospholipid biosynthetic process membrane transferase activity acyltransferase activity phosphatidylcholine acyl-chain remodeling lysophosphatidic acid acyltransferase activity metal ion binding 1-alkenylglycerophosphocholine O-acyltransferase activity 1-acylglycerophosphocholine O-acyltransferase activity 1-acylglycerophosphocholine O-acyltransferase activity 1-alkylglycerophosphocholine O-acetyltransferase activity plasmalogen synthase activity membrane organization	00564 00565 01100
1433661_at	Nlrx1	NLR family member X1	9	-44252712, -44252712, -44252712	BB830346	270151	63	nucleotide binding immune system process protein binding ATP binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane plasma membrane macrophage cytokine production negative regulation of macrophage cytokine production membrane interferon-beta production interleukin-6 production negative regulation of interferon-beta production negative regulation of interleukin-6 production negative regulation of RIG-I signaling pathway negative regulation of canonical NF-kappaB signal transduction negative regulation of canonical NF-kappaB signal transduction innate immune response negative regulation of innate immune response negative regulation of inflammatory response	04622
1418398_a_at	Tspan32	tetraspanin 32	7	143005658, 143005045	AF175771	27027	32	molecular_function intracellular anatomical structure cytoskeleton organization integrin-mediated signaling pathway blood coagulation hemostasis cell surface membrane negative regulation of myeloid dendritic cell activation T cell proliferation negative regulation of T cell proliferation defense response to protozoan regulation of defense response to virus integrin alphaIIb-beta3 complex platelet aggregation
1433966_x_at	Asns	asparagine synthetase	6	-7675164	AV212753	27053	41	nucleotide binding asparagine synthase (glutamine-hydrolyzing) activity asparagine synthase (glutamine-hydrolyzing) activity ATP binding cytosol cytosol cytosol asparagine biosynthetic process asparagine biosynthetic process glutamine metabolic process amino acid biosynthetic process ligase activity cellular response to glucose starvation identical protein binding negative regulation of apoptotic process positive regulation of mitotic cell cycle	00250 00910 01100
1418397_at	Zfp275	zinc finger protein 275	X	73342619, 73342620	BC019962	27081	33	RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II
1443932_at	Klhdc1	kelch domain containing 1	12	69241831	BQ176961	271005	10	cytoplasm cytosol Cul5-RING ubiquitin ligase complex ubiquitin-dependent protein catabolic process via the C-end degron rule pathway ubiquitin ligase-substrate adaptor activity
1454826_at	Zbtb11	zinc finger and BTB domain containing 11	16	55973803	BM195115	271377	21	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus nucleoplasm regulation of DNA-templated transcription metal ion binding
1430154_at	Vps13a	vacuolar protein sorting 13A	19	-16615365	AI666321	271564	32	molecular_function mitochondrion mitochondrial outer membrane lysosome lysosomal membrane endosome endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus lipid droplet protein targeting to vacuole lipid transport autophagy autophagy nervous system development locomotory behavior endosome membrane membrane flagellated sperm motility sperm mitochondrion organization dense core granule cytoplasmic vesicle mitochondrial membrane social behavior mitochondria-associated endoplasmic reticulum membrane protein retention in Golgi apparatus sperm midpiece neuronal dense core vesicle lumen lysosomal protein catabolic process
1426956_a_at	Trp53bp1	transformation related protein 53 binding protein 1	2	-121194834	AJ414734	27223	200	DNA damage checkpoint signaling chromosome, centromeric region kinetochore chromosome, telomeric region chromosome, telomeric region p53 binding DNA binding damaged DNA binding transcription coregulator activity protein binding nucleus nucleus nucleus nucleoplasm replication fork chromosome cytoplasm DNA repair double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining double-strand break repair via nonhomologous end joining regulation of DNA-templated transcription DNA damage response transcription factor binding nuclear body nuclear body methylated histone binding methylated histone binding site of double-strand break site of double-strand break telomeric DNA binding histone binding sequence-specific DNA binding positive regulation of isotype switching positive regulation of isotype switching positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II protein homooligomerization RNA polymerase II-specific DNA-binding transcription factor binding ubiquitin modification-dependent histone binding double-strand break repair via classical nonhomologous end joining histone reader activity DNA repair complex negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination negative regulation of double-strand break repair via homologous recombination
1430700_a_at	Pla2g7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	17	43568450	AK005158	27226	59	1-alkyl-2-acetylglycerophosphocholine esterase activity 1-alkyl-2-acetylglycerophosphocholine esterase activity phospholipid binding extracellular region extracellular space lipid metabolic process inflammatory response phospholipid catabolic process lipid catabolic process hydrolase activity low-density lipoprotein particle high-density lipoprotein particle low-density lipoprotein particle remodeling lipid oxidation plasma lipoprotein particle oxidation phosphatidylcholine catabolic process platelet activating factor metabolic process calcium-independent phospholipase A2 activity platelet activating factor catabolic process positive regulation of monocyte chemotaxis	00565 01100
1460407_at	Spib	Spi-B transcription factor (Spi-1/PU.1 related)	7	-44525994	BM244106	272382	62	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific immature B cell differentiation DNA binding DNA-binding transcription factor activity nucleus nucleus transcription regulator complex regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cell differentiation macrophage differentiation sequence-specific DNA binding positive regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding
1459522_s_at	Gyg1	glycogenin 1	3	-20122083, -20122082	AU017667	27357	41	glucose binding cytoplasm glycogen biosynthetic process glycogen biosynthetic process glycogen biosynthetic process glycogenin glucosyltransferase activity glycogenin glucosyltransferase activity transferase activity glycosyltransferase activity glycosyltransferase activity manganese ion binding protein homodimerization activity metal ion binding UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity
1423298_at	Add3	adducin 3	19	53140442, 53142755, 53143996	BM239842	27360	36	condensed nuclear chromosome actin binding protein kinase C binding structural constituent of cytoskeleton calmodulin binding cytoplasm cytoskeleton cytoskeleton plasma membrane plasma membrane brush border cell-cell junction cell cortex response to xenobiotic stimulus postsynaptic density postsynaptic density membrane positive regulation of vasoconstriction actin filament binding barbed-end actin filament capping positive regulation of cytoskeleton organization
1457753_at	Tlr13	toll-like receptor 13	X	106143274	BI655907	279572	34	toll-like receptor signaling pathway toll-like receptor signaling pathway immune system process MyD88-dependent toll-like receptor signaling pathway RNA binding transmembrane signaling receptor activity protein binding cytoplasm endosome inflammatory response inflammatory response immune response signal transduction response to virus membrane rRNA binding toll-like receptor 13 signaling pathway signaling receptor activity identical protein binding regulation of MAPK cascade innate immune response
1435357_at	Rsrp1	arginine/serine rich protein 1	4	134923624	BE652553	27981	21	spliceosomal complex assembly molecular_function cellular_component nucleus biological_process
1437478_s_at	Efhd2	EF hand domain containing 2	4	-141858141	AA409309	27984	52	calcium ion binding calcium ion binding protein binding membrane metal ion binding
1417953_at	Fam3c	FAM3 metabolism regulating signaling molecule C	6	-22306521	AK016470	27999	41	molecular_function extracellular region extracellular space Golgi apparatus multicellular organism development biological_process carbohydrate binding cytoplasmic vesicle
1456531_x_at	Prpf19	pre-mRNA processing factor 19	19	10898644, 10895230	BB458578	28000	44	DNA damage checkpoint signaling protein polyubiquitination spliceosomal tri-snRNP complex assembly spliceosomal complex assembly mRNA splicing, via spliceosome mRNA splicing, via spliceosome mRNA splicing, via spliceosome Prp19 complex Prp19 complex ubiquitin-protein transferase activity ubiquitin-protein transferase activity protein binding nucleus nucleus DNA replication factor A complex spliceosomal complex cytoplasm cytoplasm cytoskeleton DNA repair double-strand break repair via nonhomologous end joining mRNA processing DNA damage response protein localization RNA splicing lipid biosynthetic process proteasomal protein catabolic process proteasomal protein catabolic process protein ubiquitination nuclear speck transferase activity ubiquitin-ubiquitin ligase activity site of double-strand break identical protein binding positive regulation of mRNA splicing, via spliceosome positive regulation of astrocyte differentiation ubiquitin protein ligase activity protein K63-linked ubiquitination U2-type catalytic step 1 spliceosome U2-type catalytic step 2 spliceosome catalytic step 2 spliceosome	03040 04120
1420129_s_at	Rtcb	RNA 2',3'-cyclic phosphate and 5'-OH ligase	10	-85938636	AA409545	28088	39	nucleotide binding tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate in utero embryonic development placenta development RNA ligase (ATP) activity RNA ligase (ATP) activity GTP binding nucleus nucleus nuclear envelope nucleoplasm cytoplasm cytoplasm endoplasmic reticulum membrane cytosol tRNA splicing, via endonucleolytic cleavage and ligation RNA processing tRNA processing RNA ligase activity ligase activity vinculin binding intracellular membrane-bounded organelle metal ion binding tRNA-splicing ligase complex tRNA-splicing ligase complex
1434746_at	Mga	MAX gene associated	2	119897227	BG797579	29808	52	chromatin RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific cell fate specification DNA binding DNA-binding transcription factor activity nucleus nucleus transcription regulator complex regulation of DNA-templated transcription regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II protein dimerization activity MLL1 complex MLL1 complex cellular response to leukemia inhibitory factor
1453365_at	Rabgap1l	RAB GTPase activating protein 1-like	1	-160219173, -160256571	AK018430	29809	27	GTPase activator activity GTPase activator activity nucleus endosome early endosome Golgi apparatus endocytosis protein transport small GTPase binding small GTPase binding regulation of protein localization megakaryocyte development regulation of GTPase activity
1415936_at	Bcar3	breast cancer anti-estrogen resistance 3	3	122483568, 122419756	NM_013867	29815	27	phosphotyrosine residue binding lens morphogenesis in camera-type eye guanyl-nucleotide exchange factor activity protein binding cytoplasm focal adhesion epidermal growth factor receptor signaling pathway small GTPase-mediated signal transduction positive regulation of cell population proliferation insulin receptor signaling pathway membrane kinase binding positive regulation of peptidyl-serine phosphorylation positive regulation of peptidyl-serine phosphorylation positive regulation of MAPK cascade positive regulation of GTPase activity anchoring junction endothelin receptor signaling pathway
1425553_s_at	Hip1r	huntingtin interacting protein 1 related	5	123973627	AA590970	29816	47	actin binding protein binding phospholipid binding phosphatidylinositol-4,5-bisphosphate binding phosphatidylinositol-3,4,5-trisphosphate binding cytoplasm cytosol cytoskeleton plasma membrane clathrin-coated pit cell cortex endocytosis endocytosis receptor-mediated endocytosis receptor-mediated endocytosis activation of cysteine-type endopeptidase activity involved in apoptotic process activation of cysteine-type endopeptidase activity involved in apoptotic process actin filament organization postsynaptic density membrane apical plasma membrane SH3 domain binding regulation of endocytosis clathrin-coated vesicle clathrin-coated vesicle clathrin-coated vesicle clathrin binding clathrin binding negative regulation of actin filament polymerization negative regulation of actin filament polymerization cytoplasmic vesicle clathrin light chain binding clathrin light chain binding positive regulation of protein binding ruffle membrane dendrite cytoplasm regulation of actin cytoskeleton organization regulation of actin cytoskeleton organization negative regulation of Arp2/3 complex-mediated actin nucleation phosphatidylinositol binding clathrin adaptor activity clathrin adaptor activity clathrin adaptor activity identical protein binding protein homodimerization activity protein homodimerization activity neuronal cell body positive regulation of apoptotic process negative regulation of apoptotic process dendritic spine intracellular membrane-bounded organelle phosphatidylinositol-3,4-bisphosphate binding phosphatidylinositol-3,4-bisphosphate binding positive regulation of epidermal growth factor receptor signaling pathway protein heterodimerization activity clathrin coat assembly clathrin coat assembly perinuclear region of cytoplasm protein stabilization actin filament binding actin filament binding actin filament binding digestive system development regulation of gastric acid secretion membrane organization phosphatidylinositol-3,5-bisphosphate binding phosphatidylinositol-3,5-bisphosphate binding synaptic membrane postsynapse glutamatergic synapse postsynapse organization positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway positive regulation of clathrin coat assembly regulation of clathrin-dependent endocytosis positive regulation of clathrin-dependent endocytosis positive regulation of platelet-derived growth factor receptor-beta signaling pathway
1452469_a_at	Smtn	smoothelin	11	-3517521	BF578669	29856	32	negative regulation of systemic arterial blood pressure actin binding cytoplasm microtubule organizing center cytoskeleton actin cytoskeleton organization filamentous actin positive regulation of cardiac muscle contraction
1419574_at	Zfp292	zinc finger protein 292	4	-34803109	NM_013889	30046	35	DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA binding nucleus nucleus regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding
1417928_at	Pdlim4	PDZ and LIM domain 4	11	-54054927	NM_019417	30794	40	stress fiber stress fiber actin binding protein binding nucleus cytoplasm endosome cytoskeleton adherens junction heart development actin cytoskeleton membrane protein phosphatase binding protein phosphatase binding Z disc lamellipodium actin cytoskeleton organization actin cytoskeleton organization early endosome lumen filamentous actin filamentous actin recycling endosome lumen protein homodimerization activity actinin binding cell projection neuron projection dendritic spine synapse postsynaptic membrane metal ion binding perinuclear region of cytoplasm muscle alpha-actinin binding alpha-actinin binding positive regulation of stress fiber assembly muscle structure development excitatory chemical synaptic transmission
1416858_a_at	Fkbp3	FK506 binding protein 3	12	-65062431	NM_013902	30795	35	peptidyl-prolyl cis-trans isomerase activity protein binding nucleus isomerase activity
1448420_a_at	Fbxl12	F-box and leucine-rich repeat protein 12	9	-20637748, -20637748	NM_013911	30843	25	ubiquitin ligase complex cytoplasm ubiquitin-dependent protein catabolic process SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
1425086_a_at	Slamf6	SLAM family member 6	1	171917461, 171917461	AF248636	30925	48	natural killer cell differentiation natural killer cell proliferation adaptive immune response immune system process plasma membrane plasma membrane external side of plasma membrane membrane positive regulation of type II interferon production positive regulation of type II interferon production positive regulation of interleukin-17 production T cell activation innate immune response positive regulation of natural killer cell mediated cytotoxicity T-helper 17 cell lineage commitment T-helper 17 cell lineage commitment
1417010_at	Zbtb18	zinc finger and BTB domain containing 18	1	177444660, 177445820, 177444652, 177442350, 177442350, 177444937	NM_013915	30928	46	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II heterochromatin DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific in utero embryonic development DNA binding nucleus nucleus nucleus nucleoplasm regulation of transcription by RNA polymerase II multicellular organism development skeletal muscle tissue development nuclear speck cerebellum development hippocampus development cerebral cortex development sequence-specific DNA binding negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II metal ion binding neuron development homeostasis of number of cells regulation of cell division sequence-specific double-stranded DNA binding
1421998_at	Tor3a	torsin family 3, member A	1	-156653616	NM_023141	30935	24	nucleotide binding protein binding ATP binding nuclear envelope cytoplasm endoplasmic reticulum endoplasmic reticulum lumen endoplasmic reticulum lumen endoplasmic reticulum lumen ATP hydrolysis activity
1447854_s_at	H2bc21	H2B clustered histone 21	3	96221071	AV127319	319190	25	nucleosome lipopolysaccharide binding innate immune response in mucosa DNA binding protein binding extracellular space nucleus nucleoplasm nucleoplasm chromosome cytosol plasma membrane negative regulation of tumor necrosis factor-mediated signaling pathway antibacterial humoral response structural constituent of chromatin killing of cells of another organism CENP-A containing nucleosome protein heterodimerization activity defense response to Gram-negative bacterium defense response to Gram-positive bacterium antimicrobial humoral immune response mediated by antimicrobial peptide	05322
1434521_at	Rfx7	regulatory factor X, 7	9	72532239	BB148972	319758	22	RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II sequence-specific double-stranded DNA binding
1441516_a_at	C130050O18Rik	RIKEN cDNA C130050O18 gene	5	139406386, 139405283	BB527707	319772	10	molecular_function cellular_component biological_process
1454795_at	Cobll1	Cobl-like 1	2	-65088338	AV080881	319876	17	actin monomer binding
1417321_at	Zcchc7	zinc finger, CCHC domain containing 7	4	44756558	NM_138590	319885	24	molecular_function nucleic acid binding RNA binding nucleus nucleolus cytosol biological_process zinc ion binding TRAMP complex metal ion binding nuclear mRNA surveillance of mRNA 3'-end processing nuclear polyadenylation-dependent rRNA catabolic process nuclear polyadenylation-dependent snoRNA catabolic process nuclear polyadenylation-dependent snRNA catabolic process nuclear polyadenylation-dependent tRNA catabolic process nuclear polyadenylation-dependent CUT catabolic process	03018
1426550_at	Sidt1	SID1 transmembrane family, member 1	16	-44240179	AI449329	320007	21	RNA binding double-stranded RNA binding double-stranded RNA binding lysosome plasma membrane cholesterol binding membrane RNA transport RNA transmembrane transporter activity
1437514_at	Trem6l	triggering receptor expressed on myeloid cells-like 6	17	48316161	BB134165	320148	11	cell surface signaling receptor activity
1434397_at	Zdhhc17	zinc finger, DHHC domain containing 17	10	-110941779, -110941779	BM248633	320150	46	Golgi membrane Golgi membrane signaling receptor binding protein binding Golgi apparatus Golgi apparatus plasma membrane axonogenesis membrane palmitoyltransferase activity palmitoyltransferase activity palmitoyltransferase activity transferase activity acyltransferase activity peptidyl-L-cysteine S-palmitoylation protein palmitoylation protein palmitoylation protein palmitoylation protein-cysteine S-myristoyltransferase activity protein-cysteine S-palmitoyltransferase activity protein-cysteine S-palmitoyltransferase activity Golgi-associated vesicle membrane cytoplasmic vesicle identical protein binding lipoprotein transport cell projection regulation of programmed cell death intracellular membrane-bounded organelle synapse regulation of neurotrophin TRK receptor signaling pathway regulation of ERK1 and ERK2 cascade protein-cysteine S-stearoyltransferase activity
1427202_at	Etfbkmt	electron transfer flavoprotein beta subunit lysine methyltransferase	6	149141512	AV002340	320204	15	cytoplasm mitochondrion mitochondrial matrix mitochondrial matrix methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity protein-lysine N-methyltransferase activity protein-lysine N-methyltransferase activity protein-lysine N-methyltransferase activity transferase activity peptidyl-lysine methylation peptidyl-lysine trimethylation peptidyl-lysine trimethylation peptidyl-lysine trimethylation heat shock protein binding methylation protein-containing complex negative regulation of electron transfer activity negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase
1435266_at	Scai	suppressor of cancer cell invasion	2	-39066214	BB495464	320271	24	transcription corepressor activity transcription corepressor activity transcription corepressor activity protein binding nucleus nucleus nucleoplasm cytoplasm DNA-templated transcription negative regulation of signal transduction membrane negative regulation of cell migration negative regulation of cell migration nuclear membrane negative regulation of Rho protein signal transduction
1455132_at	Rasal3	RAS protein activator like 3	17	-32390658, -32390658	AV312663	320484	20	GTPase activator activity cytoplasm identical protein binding regulation of GTPase activity negative regulation of Ras protein signal transduction positive regulation of NK T cell proliferation cytoplasmic side of membrane
1455340_at	Dennd5b	DENN domain containing 5B	6	-148988068	BB763709	320560	18	guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity membrane small GTPase binding small GTPase binding positive regulation of triglyceride transport
1437202_at	Mysm1	myb-like, SWIRM and MPN domains 1	4	-94942040	BB494594	320713	49	immune system process DNA binding transcription coactivator activity transcription coactivator activity nucleus nucleoplasm nucleolus cytoplasm chromatin organization chromatin remodeling chromatin remodeling proteolysis peptidase activity metallopeptidase activity hydrolase activity regulation of cell migration protein-containing complex histone binding histone binding pigmentation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding regulation of hair follicle development metal-dependent deubiquitinase activity histone H2A deubiquitinase activity regulation of hemopoiesis
1442023_at	A530030E21Rik	RIKEN cDNA A530030E21 gene	16		BB220605	320731	7	molecular_function cellular_component biological_process
1437699_at	E430014B02Rik	RIKEN cDNA E430014B02 gene	17		BB031353	320908	7	molecular_function cellular_component biological_process
1454788_at	Arl4c	ADP-ribosylation factor-like 4C	1	-88698225	BQ176306	320982	23	nucleotide binding GTPase activity GTP binding GTP binding cytoplasm cytoplasm cytosol plasma membrane intracellular protein transport membrane endocytic recycling endocytic recycling cell projection alpha-tubulin binding
1428162_at	Lrif1	ligand dependent nuclear receptor interacting factor 1	3	106721681, 106684986	AK008209	321000	16	chromosome, telomeric region Barr body Barr body protein binding nucleus nucleoplasm chromosome regulation of DNA-templated transcription dosage compensation by inactivation of X chromosome centriolar satellite nuclear retinoic acid receptor binding
1437356_at	Gpr183	G protein-coupled receptor 183	14	-121952330	BM242490	321019	67	adaptive immune response B cell activation involved in immune response mature B cell differentiation involved in immune response immune system process dendritic cell chemotaxis G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane humoral immune response signal transduction G protein-coupled receptor signaling pathway oxysterol binding oxysterol binding T cell chemotaxis membrane osteoclast differentiation leukocyte chemotaxis leukocyte chemotaxis positive regulation of B cell proliferation positive regulation of B cell proliferation dendritic cell homeostasis cell chemotaxis T follicular helper cell differentiation positive regulation of ERK1 and ERK2 cascade regulation of astrocyte chemotaxis
1443698_at	Xaf1	XIAP associated factor 1	11	72301628	BB645745	327959	21	nucleus nucleoplasm cytoplasm mitochondrion mitochondrion apoptotic process negative regulation of protein-containing complex assembly negative regulation of type I interferon production response to interferon-beta metal ion binding molecular sequestering activity
1453160_at	Med13	mediator complex subunit 13	11	-86267032	BB244704	327987	36	transcription coregulator activity transcription coactivator activity transcription coactivator activity nucleus nucleoplasm nucleoplasm regulation of transcription by RNA polymerase II mediator complex mediator complex mediator complex cholesterol homeostasis negative regulation of DNA-binding transcription factor activity positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II nuclear thyroid hormone receptor binding positive regulation of transcription initiation by RNA polymerase II triglyceride homeostasis CKM complex
1428172_at	Prpf39	pre-mRNA processing factor 39	12	65036333	BB460975	328110	18	commitment complex mRNA 5'-splice site recognition nucleus U1 snRNP RNA processing mRNA processing RNA splicing pre-mRNA 5'-splice site binding U2-type prespliceosome
1435090_at	Tubgcp6	tubulin, gamma complex component 6	15	-89099097	BB477000	328580	16	microtubule cytoskeleton organization mitotic cell cycle spindle pole equatorial microtubule organizing center gamma-tubulin complex gamma-tubulin ring complex cytoplasm centrosome centrosome microtubule organizing center cytoskeleton microtubule microtubule nucleation microtubule nucleation microtubule binding cytoplasmic microtubule organization gamma-tubulin binding gamma-tubulin binding microtubule minus-end binding spindle assembly meiotic cell cycle
1438296_at	Slc2a4rg-ps	Slc2a4 regulator, pseudogene	2	181384249	BE632919	329584	7
1452868_at	Usp24	ubiquitin specific peptidase 24	4	106316212	AK012842	329908	26	cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity nucleus cytosol proteolysis peptidase activity cysteine-type peptidase activity protein deubiquitination protein deubiquitination hydrolase activity
1438148_at	Cxcl3	C-X-C motif chemokine ligand 3	5	90786100	BB829808	330122	23	cytokine activity protein binding extracellular region extracellular space extracellular space chemotaxis defense response inflammatory response inflammatory response immune response positive regulation of cytosolic calcium ion concentration chemokine activity chemokine activity chemokine activity neutrophil chemotaxis neutrophil chemotaxis neutrophil chemotaxis CXCR chemokine receptor binding antimicrobial humoral immune response mediated by antimicrobial peptide chemokine-mediated signaling pathway cellular response to lipopolysaccharide
1454762_at	Xkrx	X-linked Kx blood group related, X-linked	X	-134149042	BM932447	331524	14	molecular_function cellular_component biological_process membrane
1438195_at	Gpd1l	glycerol-3-phosphate dehydrogenase 1-like	9	-114899338	BB727537	333433	22	regulation of heart rate cytoplasm cytosol plasma membrane carbohydrate metabolic process glycerol-3-phosphate metabolic process NADH metabolic process glycerol-3-phosphate dehydrogenase complex positive regulation of sodium ion transport membrane oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor sodium channel regulator activity NAD metabolic process negative regulation of peptidyl-serine phosphorylation protein homodimerization activity transmembrane transporter binding glycerol-3-phosphate catabolic process glycerol-3-phosphate dehydrogenase [NAD(P)+] activity NAD binding regulation of ventricular cardiac muscle cell membrane depolarization ventricular cardiac muscle cell action potential negative regulation of protein kinase C signaling positive regulation of protein localization to cell surface regulation of sodium ion transmembrane transporter activity	00564
1434394_at	N4bp2	NEDD4 binding protein 2	5	65763520	AV116077	333789	20	endonuclease activity endonuclease activity DNA endonuclease activity protein binding ATP binding cytosol ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
1435463_s_at	Myo1d	myosin ID	11	-80482126	C76327	338367	37	microfilament motor activity microfilament motor activity nucleotide binding cytoskeletal motor activity actin binding protein binding calmodulin binding ATP binding cytoplasm cytoplasm endosome plasma membrane plasma membrane microvillus brush border brush border endocytosis actin filament organization protein transport actin cytoskeleton membrane basolateral plasma membrane myosin complex protein domain specific binding actin filament-based movement axon axolemma cytoplasmic vesicle cell projection neuron projection neuronal cell body neuronal cell body myelin sheath myelin sheath myelin sheath plasma membrane raft calcium-dependent protein binding actin filament binding actin filament binding cellular localization apical dendrite
1435432_at	Agap1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	1	89454810	BE688580	347722	33	nucleotide binding GTPase activity GTPase activity GTPase activator activity GTPase activator activity GTP binding phospholipid binding cytoplasm cytosol protein transport metal ion binding activation of GTPase activity	04144
1434681_at	Txlng	taxilin gamma	X	-162778916, -162788789	BG069603	353170	26	protein binding nucleus cytoplasm cytosol cell cycle regulation of cell cycle process membrane syntaxin binding regulation of bone mineralization nuclear membrane nuclear membrane regulation of cell cycle regulation of cell cycle DNA-binding transcription factor binding
1416958_at	Nr1d2	nuclear receptor subfamily 1, group D, member 2	14	-18204055	NM_011584	353187	72	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nuclear receptor activity nuclear receptor activity protein binding nucleus nucleus nucleoplasm cytoplasm regulation of DNA-templated transcription zinc ion binding hormone-mediated signaling pathway regulation of lipid metabolic process cell differentiation regulation of circadian rhythm regulation of circadian rhythm sequence-specific DNA binding negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II metal ion binding rhythmic process circadian behavior regulation of inflammatory response negative regulation of inflammatory response lipid homeostasis energy homeostasis sequence-specific double-stranded DNA binding regulation of skeletal muscle cell differentiation
1444090_at	Pram1	PML-RAR alpha-regulated adaptor molecule 1	17	33638094, 33638055	AI561611	378460	18	plasma membrane plasma membrane integrin-mediated signaling pathway integrin-mediated signaling pathway lipid binding protein kinase binding protein-containing complex regulation of neutrophil degranulation T cell receptor signaling pathway protein localization to plasma membrane
1431997_at	3000002C10Rik	glyceraldehyde-3-phosphate dehydrogenase pseudogene	9	-109830153	AK013857	378954	11
1445687_at	Milr1	mast cell immunoglobulin like receptor 1	11	106751225, 106751225	BE629676	380732	20	protein binding extracellular region plasma membrane membrane negative regulation of mast cell activation mast cell degranulation
1428279_a_at	Atxn7l1	ataxin 7-like 1	12	33147685, 33302514, 33315404, 33314296, 33146970, 33146967	AK013145	380753	16	molecular_function cellular_component biological_process
1455530_at	Ighd	immunoglobulin heavy constant delta	12		BE686052	380797	34	antigen binding antigen binding external side of plasma membrane immunoglobulin mediated immune response immunoglobulin mediated immune response somatic hypermutation of immunoglobulin genes B cell receptor complex positive regulation of B cell proliferation positive regulation of interleukin-1 production B cell proliferation regulation of immune response regulation of immune response
1437060_at	Olfm4	olfactomedin 4	14	80000301	AV290148	380924	51	structural molecule activity protein binding extracellular region extracellular space extracellular space extracellular space nucleoplasm mitochondrion cytosol plasma membrane immune response cell adhesion signal transduction protein-containing complex specific granule negative regulation of canonical NF-kappaB signal transduction intercellular bridge cadherin binding perinuclear region of cytoplasm negative regulation of immune response positive regulation of substrate adhesion-dependent cell spreading
1435550_at	Kmt2d	lysine (K)-specific methyltransferase 2D	15	-98831668	BB702910	381022	100	transcription cis-regulatory region binding DNA-binding transcription activator activity, RNA polymerase II-specific oocyte growth in utero embryonic development transcription coactivator activity protein binding nucleus nucleoplasm chromatin organization methyltransferase activity positive regulation of cell population proliferation regulation of gene expression transferase activity heterochromatin formation methylation positive regulation of intracellular estrogen receptor signaling pathway histone methyltransferase complex histone binding histone H3K4 methyltransferase activity histone H3K4 methyltransferase activity response to estrogen MLL3/4 complex MLL3/4 complex positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II metal ion binding oogenesis histone H3K4 monomethyltransferase activity
1456792_at	Tbc1d2	TBC1 domain family, member 2	4	-46604389	BG967046	381605	17	GTPase activator activity GTPase activator activity nucleoplasm cytoplasm cytosol plasma membrane cell junction cytoplasmic vesicle positive regulation of GTPase activity cadherin binding anchoring junction activation of GTPase activity
1435391_at	Rbm33	RNA binding motif protein 33	5	28317188	BM236842	381626	23	molecular_function nucleic acid binding RNA binding RNA binding cellular_component nucleus cytoplasm RNA export from nucleus biological_process protein-macromolecule adaptor activity oxidative single-stranded RNA demethylation regulation of mRNA stability lncRNA binding N6-methyladenosine-containing RNA reader activity
1428492_at	Glipr2	GLI pathogenesis-related 2	4	43957701	BM208214	384009	26	Golgi membrane extracellular region extracellular space Golgi apparatus positive regulation of epithelial cell migration positive regulation of epithelial to mesenchymal transition membrane protein homodimerization activity positive regulation of ERK1 and ERK2 cascade
1436941_at	Nxpe3	neurexophilin and PC-esterase domain family, member 3	16	-55839952	BB626288	385658	11	molecular_function cellular_component biological_process
1455291_s_at	Znrf2	zinc and ring finger 2	6	54816915	BG071922	387524	20	fibrillar center nucleoplasm cytoplasm cytoplasm lysosome endosome plasma membrane membrane membrane transferase activity cytoplasmic vesicle membrane protein-containing complex cell projection proteasome-mediated ubiquitin-dependent protein catabolic process intracellular membrane-bounded organelle intracellular membrane-bounded organelle synapse metal ion binding ubiquitin protein ligase activity ubiquitin protein ligase activity protein K48-linked ubiquitination
1434301_at	Lratd2	LRAT domain containing 1	15	-60818995	BE303700	399603	17	molecular_function cytoplasm plasma membrane biological_process
1435754_at	Zyg11b	zyg-ll family member B, cell cycle regulator	4	-108227754	BQ180736	414872	17	protein quality control for misfolded or incompletely synthesized proteins Cul2-RING ubiquitin ligase complex Cul2-RING ubiquitin ligase complex positive regulation of proteasomal ubiquitin-dependent protein catabolic process
1428231_at	Cpsf6	cleavage and polyadenylation specific factor 6	10	-117344667, -117344666	BB425379	432508	43	nucleic acid binding RNA binding mRNA binding mRNA binding protein binding nucleus nucleus nucleoplasm perichromatin fibrils cytoplasm mRNA cleavage and polyadenylation specificity factor complex mRNA cleavage and polyadenylation specificity factor complex mRNA cleavage factor complex mRNA processing nuclear speck mRNA 3'-end processing interchromatin granule paraspeckles ribosomal large subunit binding positive regulation of RNA export from nucleus localization protein tetramerization protein heterotetramerization mRNA alternative polyadenylation mRNA alternative polyadenylation messenger ribonucleoprotein complex assembly exon-exon junction complex binding ribonucleoprotein complex	03015
1457285_at	Zscan26	zinc finger and SCAN domain containing 26	13	-21442180	BB354728	432731	14	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus nucleoplasm cytosol regulation of transcription by RNA polymerase II metal ion binding
1455324_at	Plcxd2	phosphatidylinositol-specific phospholipase C, X domain containing 2	16	-45959260	BQ176176	433022	16	molecular_function cellular_component nucleus lipid metabolic process signal transduction phosphoric diester hydrolase activity phosphoric diester hydrolase activity biological_process lipid catabolic process hydrolase activity
1434046_at	AA467197	expressed sequence AA467197	2	122637886	BG961961	433470	18	nucleus mitochondrion mitochondrial respiratory chain complex IV response to bacterium
1455518_at	Zdhhc18	zinc finger, DHHC domain containing 18	4	-133606991	BB324402	503610	18	immune system process endoplasmic reticulum Golgi apparatus Golgi apparatus protein targeting to membrane protein localization membrane palmitoyltransferase activity palmitoyltransferase activity transferase activity acyltransferase activity peptidyl-L-cysteine S-palmitoylation peptidyl-L-cysteine S-palmitoylation protein palmitoylation protein-cysteine S-palmitoyltransferase activity protein-cysteine S-palmitoyltransferase activity innate immune response negative regulation of innate immune response negative regulation of cGAS/STING signaling pathway
1449222_at	Ebi3	Epstein-Barr virus induced gene 3	17	55952622	NM_015766	50498	106	cytokine receptor activity cytokine receptor activity cytokine activity protein binding extracellular region extracellular space external side of plasma membrane membrane cytokine-mediated signaling pathway cytokine binding T cell proliferation receptor complex interleukin-27 receptor binding
1419681_a_at	Prok2	prokineticin 2	6	-99711298	NM_015768	50501	66	angiogenesis G protein-coupled receptor binding G protein-coupled receptor binding endothelial cell proliferation endothelial cell proliferation epicardium-derived cardiac endothelial cell differentiation extracellular region chemotaxis neuropeptide signaling pathway spermatogenesis circadian rhythm negative regulation of apoptotic process positive regulation of smooth muscle contraction rhythmic process coronary vasculature development vasculogenesis involved in coronary vascular morphogenesis epicardium-derived cardiac vascular smooth muscle cell differentiation
1434958_at	Sacs	sacsin	14	61138456, 61138456	BG075163	50720	30	nucleus cytoplasm mitochondrion Hsp70 protein binding Hsp70 protein binding identical protein binding low-density lipoprotein particle receptor binding protein-folding chaperone binding proteasome binding negative regulation of inclusion body assembly
1419212_at	Icosl	icos ligand	10	78069367	NM_015790	50723	119	regulation of cytokine production adaptive immune response immune system process signaling receptor binding signaling receptor binding protein binding plasma membrane plasma membrane signal transduction external side of plasma membrane external side of plasma membrane membrane positive regulation of interleukin-4 production positive regulation of activated T cell proliferation T cell activation B cell activation identical protein binding intracellular membrane-bounded organelle isotype switching T cell receptor signaling pathway	04514 04672
1456388_at	Atp11a	ATPase, class VI, type 11A	8	12757015	AV378604	50770	36	nucleotide binding magnesium ion binding in utero embryonic development transporter activity ATP binding endosome endoplasmic reticulum endoplasmic reticulum Golgi apparatus plasma membrane plasma membrane lipid transport positive regulation of myotube differentiation positive regulation of myotube differentiation phospholipid transport membrane ATP hydrolysis activity intracellular membrane-bounded organelle phospholipid translocation metal ion binding recycling endosome recycling endosome phosphatidylethanolamine flippase activity regulation of membrane lipid distribution ATPase-coupled intramembrane lipid transporter activity ATPase-coupled intramembrane lipid transporter activity phosphatidylserine flippase activity phospholipid-translocating ATPase complex
1417009_at	C1ra	complement component 1, r subcomponent A	6	124512620	NM_023143	50909	22	immune system process serine-type endopeptidase activity serine-type endopeptidase activity calcium ion binding extracellular region extracellular space extracellular space proteolysis complement activation complement activation, classical pathway peptidase activity serine-type peptidase activity hydrolase activity zymogen activation zymogen activation identical protein binding innate immune response molecular sequestering activity	04145 04610 05150 05322
1456698_s_at	Hnrnpdl	heterogeneous nuclear ribonucleoprotein D-like	5	-100033578	BB711246	50926	41	nucleic acid binding DNA binding double-stranded DNA binding single-stranded DNA binding RNA binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm poly(A) binding poly(A) binding regulation of gene expression regulation of gene expression mRNA metabolic process poly(G) binding poly(G) binding synapse synapse
1449508_at	Il27ra	interleukin 27 receptor, alpha	8	-84030285	NM_016671	50931	162	negative regulation of cellular extravasation positive regulation of T-helper 1 type immune response negative regulation of type 2 immune response protein binding extracellular region cytoplasm plasma membrane external side of plasma membrane membrane cytokine-mediated signaling pathway cytokine binding negative regulation of interleukin-17 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production positive regulation of type II interferon production receptor complex negative regulation of neuron apoptotic process interleukin-27 receptor activity interleukin-27 receptor activity regulation of isotype switching to IgG isotypes defense response to Gram-positive bacterium negative regulation of T-helper 17 type immune response negative regulation of T cell extravasation
1434390_at	Hnrnpu	heterogeneous nuclear ribonucleoprotein U	1	-178326733, -178321107	BB200448	51810	88	negative regulation of transcription by RNA polymerase II nucleotide binding nuclear chromosome alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome chromosome, centromeric region kinetochore RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II complex binding TFIIH-class transcription factor complex binding DNA binding chromatin binding double-stranded DNA binding single-stranded DNA binding transcription corepressor activity RNA binding RNA binding RNA binding RNA binding double-stranded RNA binding single-stranded RNA binding mRNA 3'-UTR binding actin binding protein binding ATP binding nucleus nucleus nucleus nucleoplasm spliceosomal complex chromosome telomerase holoenzyme complex cytoplasm centrosome cytosol cytoskeleton chromatin organization mRNA processing cell cycle multicellular organism development regulation of mitotic cell cycle poly(A) binding RNA splicing dosage compensation by inactivation of X chromosome cell surface positive regulation of gene expression mRNA metabolic process nuclear matrix nuclear speck snRNA binding poly(C) RNA binding cell differentiation dendrite midbody chromatin DNA binding negative regulation of telomere maintenance via telomerase dendrite cytoplasm circadian regulation of gene expression protein-containing complex negative regulation of kinase activity poly(G) binding negative regulation of transcription elongation by RNA polymerase II pre-mRNA binding cytoplasmic ribonucleoprotein granule identical protein binding ribonucleoprotein complex binding sequence-specific DNA binding protein-containing complex binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II mRNA stabilization rhythmic process cell division maintenance of protein location in nucleus cardiac muscle cell development telomerase RNA binding CRD-mediated mRNA stabilization CRD-mediated mRNA stability complex catalytic step 2 spliceosome cellular response to glucocorticoid stimulus cellular response to dexamethasone stimulus mitotic spindle positive regulation of brown fat cell differentiation RNA polymerase II transcription regulator complex inactive sex chromosome inactive sex chromosome dendritic transport of messenger ribonucleoprotein complex dendritic transport of messenger ribonucleoprotein complex RNA polymerase II C-terminal domain binding lncRNA binding negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay regulation of mitotic spindle assembly regulation of chromatin organization positive regulation of attachment of mitotic spindle microtubules to kinetochore protein localization to spindle microtubule mitotic spindle midzone RNA localization to chromatin mitotic spindle microtubule cellular response to leukemia inhibitory factor sequence-specific double-stranded DNA binding promoter-specific chromatin binding promoter-specific chromatin binding promoter-specific chromatin binding adaptive thermogenesis ribonucleoprotein complex ribonucleoprotein complex ribonucleoprotein complex positive regulation of stem cell proliferation negative regulation of stem cell differentiation negative regulation of stem cell differentiation positive regulation of cytoplasmic translation	03040
1433640_at	Fubp1	far upstream element (FUSE) binding protein 1	3	152210421	BG070740	51886	55	RNA polymerase II cis-regulatory region sequence-specific DNA binding nucleic acid binding DNA binding RNA binding mRNA binding protein binding nucleus nucleus nucleoplasm cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of gene expression positive regulation of gene expression synapse synapse somatic stem cell division developmental cell growth hematopoietic stem cell proliferation positive regulation of Schwann cell migration
1453239_a_at	Ankrd22	ankyrin repeat domain 22	19	-34122548	AK012869	52024	15	molecular_function cellular_component biological_process
1429005_at	Mfhas1	malignant fibrous histiocytoma amplified sequence 1	8	35587788	BB107412	52065	18	nucleotide binding immune system process GTP binding cytoplasm defense response inflammatory response inflammatory response signal transduction negative regulation of signal transduction erythrocyte differentiation ubiquitin protein ligase binding regulation of toll-like receptor signaling pathway negative regulation of toll-like receptor 2 signaling pathway negative regulation of toll-like receptor 2 signaling pathway positive regulation of toll-like receptor 2 signaling pathway positive regulation of toll-like receptor 2 signaling pathway negative regulation of toll-like receptor 4 signaling pathway negative regulation of protein dephosphorylation regulation of macrophage activation innate immune response innate immune response positive regulation of JNK cascade negative regulation of inflammatory response protein phosphatase 2A binding positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of ERK1 and ERK2 cascade negative regulation of protein localization to nucleus positive regulation of p38MAPK cascade
1435342_at	Kcnk6	potassium inwardly-rectifying channel, subfamily K, member 6	7	-29221927	BG069589	52150	21	regulation of systemic arterial blood pressure negative regulation of systemic arterial blood pressure potassium channel activity plasma membrane outward rectifier potassium channel activity potassium ion leak channel activity stabilization of membrane potential regulation of resting membrane potential potassium ion transmembrane transport
1438000_x_at	Zfp622	zinc finger protein 622	15	25984365	BB026724	52521	21	nucleic acid binding nucleus nucleoplasm nucleolus cytoplasm Golgi apparatus cytosol zinc ion binding intrinsic apoptotic signaling pathway in response to oxidative stress preribosome, large subunit precursor positive regulation of kinase activity ribosome biogenesis ribosomal large subunit biogenesis ribosomal large subunit biogenesis positive regulation of apoptotic process positive regulation of MAPK cascade positive regulation of JNK cascade metal ion binding preribosome binding
1419985_s_at	Ccdc69	coiled-coil domain containing 69	11	-55049737	C87579	52570	14	nucleus cytoplasm cytoplasm cytoskeleton microtubule binding spindle midzone spindle midzone assembly
1424333_at	Trmt10c	tRNA methyltransferase 10C, mitochondrial RNase P subunit	16	-56033719	BC023147	52575	26	tRNA binding tRNA binding mitochondrial RNA 5'-end processing nucleus nucleoplasm nucleoplasm mitochondrion mitochondrion mitochondrion mitochondrion tRNA processing methyltransferase activity transferase activity mitochondrial ribonuclease P complex methylation mitochondrial nucleoid identical protein binding tRNA methyltransferase complex tRNA (guanosine(9)-N1)-methyltransferase activity positive regulation of mitochondrial translation positive regulation of mitochondrial translation mitochondrial tRNA methylation mRNA methylation mitochondrial tRNA processing mitochondrial tRNA 5'-end processing mitochondrial tRNA 5'-end processing tRNA (adenine(9)-N1)-methyltransferase activity mitochondrial tRNA 3'-end processing
1433557_at	Cbx7	chromobox 7	15	-79915806	AV024881	52609	60	negative regulation of transcription by RNA polymerase II chromatin heterochromatin chromatin binding RNA binding single-stranded RNA binding protein binding nucleus nucleus nucleoplasm chromosome cytosol chromatin organization PcG protein complex positive regulation of transcription elongation by RNA polymerase II methylated histone binding PRC1 complex sebaceous gland development
1430447_a_at	Lair1	leukocyte-associated Ig-like receptor 1	7	-4007072	AK017222	52855	32	plasma membrane plasma membrane membrane
1416708_a_at	Gramd1a	GRAM domain containing 1A	7	-31130126	NM_027898	52857	25	endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane cytosol plasma membrane plasma membrane plasma membrane lipid transport autophagy lipid binding cholesterol binding cholesterol binding membrane cytoplasmic vesicle intracellular sterol transport organelle membrane contact site cellular response to cholesterol cholesterol transfer activity cholesterol transfer activity endoplasmic reticulum-plasma membrane contact site endoplasmic reticulum-plasma membrane contact site
1417168_a_at	Usp2	ubiquitin specific peptidase 2	9	44069428, 44084919, 44067020	AI553394	53376	50	negative regulation of transcription by RNA polymerase II cysteine-type deubiquitinase activity protein binding nucleus cytoplasm cytoplasm centrosome proteolysis cell cycle muscle organ development peptidase activity cysteine-type peptidase activity membrane protein deubiquitination protein deubiquitination hydrolase activity cyclin binding ubiquitin protein ligase binding circadian regulation of gene expression identical protein binding entrainment of circadian clock by photoperiod locomotor rhythm positive regulation of mitotic cell cycle metal ion binding perinuclear region of cytoplasm rhythmic process circadian behavior negative regulation of skeletal muscle tissue development positive regulation of skeletal muscle tissue development protein stabilization negative regulation of calcium ion transport
1420477_at	Nap1l1	nucleosome assembly protein 1-like 1	10	111473226	BG064031	53605	48	chromatin chromatin binding protein binding nucleus nucleus cytoplasm nucleosome assembly nucleosome assembly nervous system development kinase binding histone binding positive regulation of neurogenesis histone chaperone activity positive regulation of neural precursor cell proliferation
1450784_at	Reck	reversion-inducing-cysteine-rich protein with kazal motifs	4	43875529	NM_016678	53614	66	blood vessel maturation blood vessel maturation blood vessel maturation sprouting angiogenesis endopeptidase inhibitor activity endopeptidase inhibitor activity endopeptidase inhibitor activity serine-type endopeptidase inhibitor activity protein binding plasma membrane plasma membrane plasma membrane embryo implantation metalloendopeptidase inhibitor activity negative regulation of peptidase activity coreceptor activity membrane Wnt signaling pathway Wnt-protein binding extracellular matrix organization extracellular matrix organization negative regulation of cell migration peptidase inhibitor activity embryonic forelimb morphogenesis positive regulation of Notch signaling pathway regulation of angiogenesis canonical Wnt signaling pathway regulation of establishment of blood-brain barrier positive regulation of canonical Wnt signaling pathway side of membrane negative regulation of metalloendopeptidase activity negative regulation of metalloendopeptidase activity negative regulation of metalloendopeptidase activity Wnt signalosome
1448221_at	Ddx39b	DEAD box helicase 39b	17	35241745, 35242816	BC011067	53817	44	nucleotide binding spliceosomal complex assembly transcription export complex mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding RNA helicase activity RNA helicase activity mRNA binding helicase activity ATP binding nucleus spliceosomal complex U4 snRNP U6 snRNP cytoplasm mRNA processing mRNA export from nucleus mRNA export from nucleus ATP-dependent activity, acting on RNA RNA splicing RNA secondary structure unwinding nuclear matrix nuclear speck nuclear speck hydrolase activity ATP hydrolysis activity U6 snRNA binding U4 snRNA binding protein-containing complex identical protein binding ATP-dependent protein binding protein-containing complex binding positive regulation of translation mRNA transport positive regulation of cell growth involved in cardiac muscle cell development positive regulation of vascular associated smooth muscle cell proliferation positive regulation of DNA biosynthetic process	03013 03015 03040
1423103_at	Rfx5	regulatory factor X, 5 (influences HLA class II expression)	3	94954107, 94954515	BB392192	53970	32	negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II intracellular membrane-bounded organelle sequence-specific DNA binding positive regulation of transcription by RNA polymerase II RNA polymerase II transcription regulator complex sequence-specific double-stranded DNA binding	04612 05340
1427564_at	Diaph2	diaphanous related formin 2	X	129749741	Y15910	54004	41	actin binding protein binding nucleolus endoplasmic reticulum actin filament multicellular organism development protein localization cellular component organization axon midline choice point recognition actin cytoskeleton organization actin filament polymerization actin filament polymerization cell differentiation small GTPase binding intracellular membrane-bounded organelle ephrin receptor signaling pathway oogenesis negative regulation of neuron projection regeneration multicellular organismal locomotion neuron projection retraction	04810
1417244_a_at	Irf7	interferon regulatory factor 7	7	-141263182	NM_016850	54123	270	chromatin transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding immune system process immune system process cytoplasmic pattern recognition receptor signaling pathway regulation of adaptive immune response DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm cytoplasm cytosol regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of gene expression immunoglobulin mediated immune response positive regulation of type I interferon production positive regulation of type I interferon production positive regulation of type I interferon production type I interferon production positive regulation of interferon-alpha production positive regulation of interferon-alpha production positive regulation of interferon-beta production positive regulation of interferon-beta production regulation of MyD88-dependent toll-like receptor signaling pathway regulation of MyD88-independent toll-like receptor signaling pathway innate immune response regulation of innate immune response positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II defense response to virus defense response to virus type I interferon-mediated signaling pathway positive regulation of type I interferon-mediated signaling pathway sequence-specific double-stranded DNA binding	04620 04622 04623 05160
1439953_at	Pmm2	phosphomannomutase 2	16	8637706	BB709170	54128	28	phosphomannomutase activity phosphomannomutase activity nucleoplasm cytoplasm cytosol cytosol mannose metabolic process protein N-linked glycosylation GDP-mannose biosynthetic process isomerase activity neuronal cell body metal ion binding	00051 00520 01100
1422576_at	Atxn10	ataxin 10	15	85336254	NM_016843	54138	42	protein binding cytoplasm cytosol cytosol plasma membrane nervous system development enzyme binding dendrite neuron projection development neuron projection development identical protein binding neuronal cell body perinuclear region of cytoplasm cilium assembly
1418301_at	Irf6	interferon regulatory factor 6	1	193153111	NM_016851	54139	93	transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific immune system process DNA binding DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II cell population proliferation negative regulation of cell population proliferation negative regulation of keratinocyte proliferation cell differentiation keratinocyte differentiation sequence-specific DNA binding skin development skin development keratinocyte proliferation keratinocyte proliferation positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II cell development roof of mouth development limb development mammary gland epithelial cell differentiation stem cell proliferation cranial skeletal system development sequence-specific double-stranded DNA binding negative regulation of stem cell proliferation
1436598_at	Icos	inducible T cell co-stimulator	1	60977913	AV313923	54167	224	T cell tolerance induction T cell tolerance induction protein binding plasma membrane external side of plasma membrane membrane T cell costimulation T cell costimulation cell-cell adhesion cell-cell adhesion	04514 04660 04672 05340
1422850_at	Pabpn1	poly(A) binding protein, nuclear 1	14	54894142	AV028400	54196	55	MAPK cascade nucleic acid binding RNA binding protein binding nucleus nucleus nucleus cytoplasm cytosol mRNA processing poly(A) binding poly(A) binding poly(A)+ mRNA export from nucleus regulation of mRNA 3'-end processing nuclear inclusion body protein self-association RNA polymerase binding cellular response to lipopolysaccharide positive regulation of polynucleotide adenylyltransferase activity ribonucleoprotein complex ribonucleoprotein complex	03015
1427736_a_at	Ccrl2	C-C motif chemokine receptor-like 2	9	-111054833, -111054833, -111054833	AJ318863	54199	39	G protein-coupled receptor activity chemokine receptor activity cytoplasm plasma membrane chemotaxis inflammatory response inflammatory response immune response signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration external side of plasma membrane membrane C-C chemokine receptor activity C-C chemokine receptor activity calcium-mediated signaling C-C chemokine binding chemokine receptor binding chemokine receptor binding CCR chemokine receptor binding cell chemotaxis chemokine-mediated signaling pathway
1416441_at	Cpq	carboxypeptidase Q	15	33083128	BB468025	54381	16	carboxypeptidase activity extracellular region extracellular space extracellular space extracellular space cytoplasm lysosome lysosome endoplasmic reticulum Golgi apparatus proteolysis proteolysis thyroid hormone generation thyroid hormone generation peptidase activity metallopeptidase activity hydrolase activity protein homodimerization activity peptide catabolic process peptide catabolic process intracellular membrane-bounded organelle metal ion binding metallodipeptidase activity metallodipeptidase activity
1417793_at	Irgm2	immunity-related GTPase family M member 2	11	58214976	NM_019440	54396	27	autophagosome assembly Golgi membrane Golgi membrane nucleotide binding autophagosome membrane positive regulation of protein phosphorylation immune system process GTPase activity GTPase activity GTPase activity GTPase activity G protein activity GTP binding cytoplasm mitochondrion vacuolar membrane endoplasmic reticulum membrane Golgi apparatus cytosol cytosol defense response response to bacterium positive regulation of autophagy positive regulation of peptidyl-threonine phosphorylation membrane hydrolase activity protein kinase binding protein-macromolecule adaptor activity cytoplasmic vesicle killing of cells of another organism protein destabilization negative regulation of type I interferon production positive regulation of peptidyl-serine phosphorylation cellular response to interferon-beta defense response to bacterium defense response to protozoan negative regulation of canonical NF-kappaB signal transduction regulation of protein-containing complex assembly protein serine/threonine kinase activator activity protein targeting to vacuolar membrane innate immune response negative regulation of defense response to virus CARD domain binding negative regulation of inflammatory response protein stabilization defense response to Gram-negative bacterium BH3 domain binding positive regulation of type II interferon-mediated signaling pathway regulation of protein complex stability protein lipidation involved in autophagosome assembly CAMKK-AMPK signaling cascade protein-containing complex assembly nucleotide-binding oligomerization domain containing 2 signaling pathway protein targeting to vacuole involved in autophagy cellular response to lipopolysaccharide positive regulation of protein serine/threonine kinase activity positive regulation of mitochondrial fission cellular response to virus negative regulation of cGAS/STING signaling pathway negative regulation of non-canonical inflammasome complex assembly negative regulation of NLRP3 inflammasome complex assembly positive regulation of autophagosome maturation positive regulation of mitophagy cardiolipin binding positive regulation of xenophagy positive regulation of lysosome organization
1460283_at	Mefv	Mediterranean fever	16	-3707214	NM_019453	54483	37	pattern recognition receptor signaling pathway immune system process actin binding nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytosol cytosol cytoskeleton microtubule microtubule associated complex inflammatory response zinc ion binding regulation of gene expression positive regulation of autophagy protein ubiquitination cytoplasmic vesicle regulation of interleukin-1 beta production negative regulation of interleukin-1 beta production negative regulation of interleukin-12 production positive regulation of interleukin-1 beta production positive regulation of interleukin-1 beta production response to type II interferon identical protein binding cell projection innate immune response innate immune response metal ion binding negative regulation of inflammatory response positive regulation of inflammatory response ubiquitin protein ligase activity canonical inflammasome complex pyroptosis negative regulation of macrophage inflammatory protein 1 alpha production negative regulation of cytokine production involved in inflammatory response negative regulation of NLRP3 inflammasome complex assembly pyroptosome complex assembly positive regulation of cysteine-type endopeptidase activity	04621
1425814_a_at	Calcrl	calcitonin receptor-like	2	-84330626	AF209905	54598	47	angiogenesis angiogenesis adrenomedullin receptor activity adrenomedullin receptor activity calcitonin gene-related peptide receptor activity calcitonin gene-related peptide receptor activity calcitonin gene-related peptide receptor activity transmembrane signaling receptor activity G protein-coupled receptor activity calcitonin receptor activity cytoplasm lysosome endosome endoplasmic reticulum plasma membrane plasma membrane calcium ion transport signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway heart development cell population proliferation positive regulation of cell population proliferation protein transport membrane receptor internalization negative regulation of smooth muscle contraction smooth muscle cell proliferation cellular response to sucrose stimulus neuronal dense core vesicle adrenomedullin receptor complex positive regulation of vascular associated smooth muscle cell proliferation CGRP receptor complex calcitonin gene-related peptide receptor signaling pathway adrenomedullin binding adrenomedullin receptor signaling pathway adrenomedullin receptor signaling pathway vascular associated smooth muscle cell proliferation	04080 04270
1416996_at	Tbc1d8	TBC1 domain family, member 8	1	-39371495, -39371495, -39373312	BC005421	54610	19	GTPase activator activity GTPase activator activity activation of GTPase activity
1417894_at	Adgrg3	adhesion G protein-coupled receptor G3	8	95017691	NM_025309	54672	22	transmembrane signaling receptor activity G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane plasma membrane signal transduction cell surface receptor signaling pathway G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway membrane B cell differentiation regulation of cell migration negative regulation of CREB transcription factor activity negative regulation of non-canonical NF-kappaB signal transduction
1416381_a_at	Prdx5	peroxiredoxin 5	19	-6906696	BC008174	54683	73	RNA polymerase III transcription regulatory region sequence-specific DNA binding peroxidase activity signaling receptor binding signaling receptor binding protein binding nucleus cytoplasm cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion peroxisome peroxisome peroxisomal matrix peroxisomal matrix cytosol response to oxidative stress response to oxidative stress thioredoxin peroxidase activity thioredoxin peroxidase activity antioxidant activity antioxidant activity negative regulation of transcription by RNA polymerase III oxidoreductase activity cytoplasmic vesicle positive regulation of collagen biosynthetic process cellular response to oxidative stress cellular response to oxidative stress cellular response to reactive oxygen species hydrogen peroxide catabolic process hydrogen peroxide catabolic process hydrogen peroxide catabolic process identical protein binding cysteine-type endopeptidase inhibitor activity involved in apoptotic process negative regulation of apoptotic process intracellular membrane-bounded organelle cell redox homeostasis perinuclear region of cytoplasm negative regulation of oxidoreductase activity regulation of apoptosis involved in tissue homeostasis NADPH oxidation peroxynitrite reductase activity thioredoxin-dependent peroxiredoxin activity reactive nitrogen species metabolic process	04146
1433977_at	Hs3st3b1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	11	-63884692	BG918344	54710	28	branching involved in ureteric bud morphogenesis Golgi apparatus plasma membrane glycosaminoglycan biosynthetic process protein sulfation sulfotransferase activity [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity heparan sulfate proteoglycan biosynthetic process membrane transferase activity [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity	00534
1451564_at	Parp14	poly (ADP-ribose) polymerase family, member 14	16	-35832877	BC021340	547253	33	immune system process transcription corepressor activity NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity protein binding nucleus nucleus cytoplasm cytoplasm cytoplasm cytosol plasma membrane negative regulation of gene expression negative regulation of gene expression transferase activity glycosyltransferase activity nucleotidyltransferase activity enzyme binding positive regulation of tyrosine phosphorylation of STAT protein negative regulation of tyrosine phosphorylation of STAT protein innate immune response negative regulation of type II interferon-mediated signaling pathway negative regulation of type II interferon-mediated signaling pathway protein poly-ADP-ribosylation protein poly-ADP-ribosylation NAD+ binding positive regulation of interleukin-4-mediated signaling pathway positive regulation of interleukin-4-mediated signaling pathway NAD+-protein ADP-ribosyltransferase activity NAD+-protein ADP-ribosyltransferase activity
1418392_a_at	Gbp3	guanylate binding protein 3	3	142560355, 142560043	NM_018734	55932	28	nucleotide binding activation of innate immune response immune system process GTPase activity GTPase activity GTP binding GTP binding nucleus cytoplasm Golgi apparatus cytosol cytosol plasma membrane membrane hydrolase activity symbiont-containing vacuole membrane cytoplasmic vesicle cytoplasmic vesicle cellular response to interferon-beta defense response to bacterium identical protein binding protein homodimerization activity defense response to protozoan defense response to protozoan adhesion of symbiont to host innate immune response perinuclear region of cytoplasm defense response to Gram-positive bacterium defense response to Gram-positive bacterium cytolysis in another organism cellular response to lipopolysaccharide cellular response to type II interferon cellular response to type II interferon cellular response to tumor necrosis factor positive regulation of pyroptosis
1423191_at	Fnbp4	formin binding protein 4	2	90745557	AK013152	55935	27	protein binding nucleoplasm biological_process
1432195_s_at	Ccnl2	cyclin L2	4	155812488	AK008585	56036	28	cyclin-dependent protein kinase holoenzyme complex protein binding nucleus nucleus nucleoplasm regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cyclin-dependent protein serine/threonine kinase regulator activity cyclin-dependent protein serine/threonine kinase regulator activity regulation of apoptotic process intracellular membrane-bounded organelle regulation of RNA splicing regulation of centrosome cycle regulation of cell cycle
1418131_at	Samhd1	SAM domain and HD domain, 1	2	-157119560, -157097533	NM_018851	56045	51	nucleotide binding double-strand break repair via homologous recombination immune system process nucleic acid binding single-stranded DNA binding RNA binding catalytic activity GTP binding nucleus nucleus nucleoplasm chromosome plasma membrane dGTP catabolic process dGTP catabolic process DNA replication DNA repair DNA damage response metabolic process zinc ion binding dGTPase activity dGTPase activity dGTPase activity deoxyribonucleotide catabolic process somatic hypermutation of immunoglobulin genes hydrolase activity triphosphoric monoester hydrolase activity triphosphoric monoester hydrolase activity dGTP binding site of double-strand break identical protein binding innate immune response regulation of innate immune response regulation of innate immune response dATP catabolic process metal ion binding protein homotetramerization protein homotetramerization defense response to virus defense response to virus negative regulation of type I interferon-mediated signaling pathway negative regulation of type I interferon-mediated signaling pathway tetraspanin-enriched microdomain DNA strand resection involved in replication fork processing
1434434_s_at	Tcerg1	transcription elongation regulator 1 (CA150)	18	42511486	AW557777	56070	40	negative regulation of transcription by RNA polymerase II DNA-binding transcription factor activity transcription coregulator activity transcription coregulator activity transcription corepressor activity nucleus nucleus nucleoplasm DNA-templated transcription regulation of DNA-templated transcription mRNA processing RNA splicing nuclear matrix identical protein binding ubiquitin-like protein conjugating enzyme binding positive regulation of transcription by RNA polymerase II RNA polymerase II-specific DNA-binding transcription factor binding RNA polymerase binding RNA polymerase binding proline-rich region binding	03040
1436038_a_at	Pigp	phosphatidylinositol glycan anchor biosynthesis, class P	16	-94364451, -94364451, -94364451, -94364451, -94358762	BF318238	56176	22	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane GPI anchor biosynthetic process GPI anchor biosynthetic process GPI anchor biosynthetic process membrane phosphatidylinositol N-acetylglucosaminyltransferase activity	00563 01100
1417523_at	Plek	pleckstrin	11	-16971205	AF181829	56193	19	protein kinase C binding cytoplasm plasma membrane vesicle docking involved in exocytosis integrin-mediated signaling pathway positive regulation of platelet activation negative regulation of inositol phosphate biosynthetic process positive regulation of inositol-polyphosphate 5-phosphatase activity cell projection organization actin cytoskeleton organization positive regulation of actin filament depolymerization positive regulation of actin filament depolymerization phospholipase C-inhibiting G protein-coupled receptor signaling pathway cortical actin cytoskeleton organization ruffle organization positive regulation of actin filament bundle assembly ruffle membrane positive regulation of integrin activation intracellular signal transduction protein homodimerization activity phosphatidylinositol-3,4-bisphosphate binding negative regulation of G protein-coupled receptor signaling pathway phosphatidylinositol metabolic process regulation of cell diameter thrombin-activated receptor signaling pathway thrombin-activated receptor signaling pathway platelet aggregation protein kinase C signaling protein secretion by platelet
1448706_at	Tdp2	tyrosyl-DNA phosphodiesterase 2	13	24831658	NM_019551	56196	32	magnesium ion binding single-stranded DNA binding single-stranded DNA binding catalytic activity nuclease activity endonuclease activity nucleus nucleoplasm cytoplasm cytoplasm DNA repair double-strand break repair double-strand break repair DNA damage response phosphoric diester hydrolase activity aggresome nuclear body PML body PML body hydrolase activity manganese ion binding tyrosyl-RNA phosphodiesterase activity metal ion binding neuron development 5'-tyrosyl-DNA phosphodiesterase activity 5'-tyrosyl-DNA phosphodiesterase activity
1422624_at	Rev1	REV1, DNA directed polymerase	1	-38052785	NM_019570	56210	60	DNA binding damaged DNA binding DNA-directed DNA polymerase activity protein binding nucleus DNA repair DNA damage response response to UV transferase activity nucleotidyltransferase activity deoxycytidyl transferase activity deoxycytidyl transferase activity error-prone translesion synthesis error-prone translesion synthesis metal ion binding error-free translesion synthesis DNA biosynthetic process
1451146_at	Zfp386	zinc finger protein 386 (Kruppel-like)	12	116047723	BC004747	56220	21	negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific chromatin binding double-stranded DNA binding nucleus regulation of transcription by RNA polymerase II
1429710_at	Styx	serine/threonine/tyrosine interaction protein	14	45351185	BB812465	56291	17	pseudophosphatase activity protein binding nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytoplasm spermatogenesis negative regulation of protein binding negative regulation of protein binding MAPK export from nucleus negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process regulation of ERK1 and ERK2 cascade regulation of ERK1 and ERK2 cascade F-box domain binding F-box domain binding
1419665_a_at	Nupr1	nuclear protein transcription regulator 1	7	-126623245	NM_019738	56312	71	acute inflammatory response DNA binding chromatin binding transcription coactivator activity protein binding nucleus nucleus nucleoplasm cytoplasm protein acetylation negative regulation of cell population proliferation male gonad development response to toxic substance regulation of autophagy negative regulation of autophagy negative regulation of autophagy negative regulation of cardiac muscle cell apoptotic process acetyltransferase activator activity positive regulation of protein modification process protein-DNA complex skeletal muscle cell differentiation intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of apoptotic process negative regulation of DNA-binding transcription factor activity positive regulation of neuron apoptotic process fibroblast apoptotic process intercellular bridge negative regulation of cell cycle negative regulation of cell cycle negative regulation of cell cycle positive regulation of cell cycle negative regulation of glycolytic process fibroblast proliferation negative regulation of fibroblast proliferation perinuclear region of cytoplasm negative regulation of epithelial cell proliferation negative regulation of programmed necrotic cell death protein-containing complex assembly positive regulation of neuroinflammatory response positive regulation of proteasomal protein catabolic process negative regulation of autophagosome assembly positive regulation of oxidative phosphorylation negative regulation of epithelial cell apoptotic process negative regulation of type B pancreatic cell proliferation regulation of response to endoplasmic reticulum stress regulation of female gonad development positive regulation of fibroblast apoptotic process positive regulation of intrinsic apoptotic signaling pathway
1460329_at	B4galt6	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6	18	-20684598	BG066773	56386	29	lactosylceramide biosynthetic process Golgi apparatus Golgi apparatus carbohydrate metabolic process lipid metabolic process sphingolipid metabolic process glycosphingolipid biosynthetic process glycosphingolipid biosynthetic process galactosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity ganglioside biosynthetic process via lactosylceramide membrane transferase activity glycosyltransferase activity central nervous system neuron axonogenesis central nervous system myelination sphingolipid biosynthetic process neuron maturation metal ion binding glycosylation	00600 01100
1424973_at	Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	5	-145977193, -145977193	AF204959	56388	18	monooxygenase activity iron ion binding endoplasmic reticulum steroid metabolic process testosterone 16-alpha-hydroxylase activity steroid hydroxylase activity retinoic acid 4-hydroxylase activity response to bacterium membrane oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen heme binding intracellular membrane-bounded organelle metal ion binding testosterone 6-beta-hydroxylase activity testosterone 6-beta-hydroxylase activity aromatase activity oxidative demethylation estrogen 16-alpha-hydroxylase activity estrogen 2-hydroxylase activity	00140 00591 00830 00980 00982 00983 01100
1433669_at	Akap8	A kinase anchor protein 8	17	-32303671	BB037566	56399	50	chromatin condensed chromosome condensed chromosome female pronucleus immune system process DNA binding chromatin binding double-stranded DNA binding protein binding nucleus nucleus nucleoplasm nucleolus cytoplasm mitotic chromosome condensation mitotic chromosome condensation zinc ion binding protein transport nuclear matrix nuclear matrix nuclear matrix negative regulation of tumor necrosis factor production protein kinase A regulatory subunit binding protein kinase A regulatory subunit binding histone deacetylase binding cell cycle G2/M phase transition innate immune response metal ion binding NF-kappaB binding cellular response to lipopolysaccharide cellular response to prostaglandin E stimulus
1417124_at	Dstn	destrin	2	143915330	NM_019771	56431	76	cytokinesis actin binding cytoplasm cytoplasm actin cytoskeleton actin cytoskeleton actin filament depolymerization actin filament depolymerization actin filament fragmentation actin filament fragmentation positive regulation of actin filament depolymerization cortical actin cytoskeleton cell motility actin filament severing actin filament binding actin filament binding actin filament binding
1454811_a_at	Serinc1	serine incorporator 1	10	-57515774	AV026664	56442	26	endoplasmic reticulum endoplasmic reticulum membrane plasma membrane plasma membrane lipid metabolic process phosphatidylserine metabolic process sphingolipid metabolic process phospholipid biosynthetic process membrane membrane enzyme binding protein-macromolecule adaptor activity membrane biogenesis
1416983_s_at	Foxo1	forkhead box O1	3	52268336	AI462296	56458	820	RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific transcription coactivator binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific blood vessel development nucleic acid binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm regulation of gluconeogenesis regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II autophagy apoptotic process DNA damage response beta-catenin binding transcription factor binding insulin receptor signaling pathway insulin receptor signaling pathway insulin receptor signaling pathway cellular response to starvation gene expression positive regulation of autophagy cell differentiation chromatin DNA binding ubiquitin protein ligase binding response to insulin cellular response to insulin stimulus negative regulation of stress-activated MAPK cascade cellular response to oxidative stress regulation of cell population proliferation glucose homeostasis positive regulation of apoptotic process negative regulation of apoptotic process sequence-specific DNA binding sequence-specific DNA binding negative regulation of fat cell differentiation positive regulation of gluconeogenesis positive regulation of gluconeogenesis positive regulation of protein catabolic process positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II negative regulation of insulin secretion protein phosphatase 2A binding canonical Wnt signaling pathway response to fatty acid cellular response to hyperoxia cellular response to nitric oxide negative regulation of canonical Wnt signaling pathway neuronal stem cell population maintenance negative regulation of cardiac muscle hypertrophy in response to stress promoter-specific chromatin binding regulation of neural precursor cell proliferation regulation of reactive oxygen species metabolic process	04910 05200 05215
1423350_at	Socs5	suppressor of cytokine signaling 5	17	87107678	AA510713	56468	35	epidermal growth factor receptor binding protein binding cytoplasm phosphatidylinositol 3-kinase complex epidermal growth factor receptor signaling pathway negative regulation of epidermal growth factor-activated receptor activity receptor signaling pathway via JAK-STAT negative regulation of signal transduction kinase inhibitor activity cytokine-mediated signaling pathway receptor tyrosine kinase binding positive regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of interleukin-6 production intracellular signal transduction positive regulation of T-helper 1 cell differentiation negative regulation of T-helper 2 cell differentiation phosphatidylinositol phosphate biosynthetic process 1-phosphatidylinositol-3-kinase regulator activity negative regulation of inflammatory response cellular response to low-density lipoprotein particle stimulus negative regulation of monocyte chemotactic protein-1 production vascular endothelial cell response to fluid shear stress negative regulation of endothelial cell activation	04630
1422064_a_at	Zbtb20	zinc finger and BTB domain containing 20	16	43247283, 42907644	AY028963	56490	339	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific regulation of cytokine production regulation of immune system process DNA binding nucleus nucleoplasm nucleoplasm cytoplasm negative regulation of gene expression nuclear body positive regulation of interferon-beta production positive regulation of interferon-beta production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of glycolytic process negative regulation of DNA-templated transcription metal ion binding positive regulation of lipid biosynthetic process lipid homeostasis cellular response to glucose stimulus sequence-specific double-stranded DNA binding
1447806_s_at	Srpk3	serine/arginine-rich protein specific kinase 3	X	73774404	BB036235	56504	18	nucleotide binding spliceosomal complex assembly protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus cytoplasm protein phosphorylation multicellular organism development muscle organ development skeletal muscle tissue development kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation cell differentiation intracellular signal transduction regulation of mRNA processing muscle tissue development
1422852_at	Cib2	calcium and integrin binding family member 2	9	-54544793	NM_019686	56506	32	magnesium ion binding magnesium ion binding photoreceptor outer segment photoreceptor inner segment integrin binding calcium ion binding calcium ion binding calcium ion binding cytoplasm cytoplasm cytosol plasma membrane muscle tendon junction positive regulation of cytosolic calcium ion concentration membrane neuromuscular junction stereocilium stereocilium stereocilium cuticular plate sarcolemma protein homodimerization activity cell projection protein-containing complex binding photoreceptor cell maintenance metal ion binding calcium ion homeostasis calcium ion homeostasis cellular response to ATP cell periphery
1425518_at	Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	2	71981214, 72054616, 71981214	AK004874	56508	94	nucleotide binding photoreceptor outer segment photoreceptor inner segment guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity protein binding cytoplasm cytosol plasma membrane brush border exocytosis adenylate cyclase-modulating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway adenylate cyclase-activating G protein-coupled receptor signaling pathway small GTPase-mediated signal transduction Ras protein signal transduction postsynaptic density positive regulation of smooth muscle cell migration membrane basolateral plasma membrane apical plasma membrane calcium-ion regulated exocytosis regulation of exocytosis insulin secretion axon dendrite growth cone cAMP binding cAMP binding protein-macromolecule adaptor activity small GTPase binding positive regulation of insulin secretion protein-containing complex intracellular signal transduction neuronal cell body dendritic spine positive regulation of GTPase activity cone cell pedicle protein-containing complex binding hormone secretion positive regulation of protein secretion regulation of dendrite development negative regulation of synaptic transmission excitatory synapse hippocampal mossy fiber to CA3 synapse hippocampal mossy fiber to CA3 synapse regulation of synaptic vesicle cycle regulation of synaptic vesicle cycle regulation of neurotransmitter receptor localization to postsynaptic specialization membrane glutamatergic synapse regulation of postsynapse organization positive regulation of neuronal action potential	04670
1436819_at	Septin6	septin 6	X	-36911271, -36913443	BG920446	56526	63	nucleotide binding chromosome, centromeric region kinetochore GTPase activity protein binding GTP binding chromosome cytoplasm cytoskeleton cilium septin ring septin ring cell cycle spermatogenesis synaptic vesicle microtubule cytoskeleton cell differentiation septin complex septin complex septin complex motile cilium cell division site cleavage furrow septin collar cell projection axon terminus cell division molecular adaptor activity cilium assembly cytoskeleton-dependent cytokinesis sperm annulus presynapse
1415897_a_at	Mgst1	microsomal glutathione S-transferase 1	6	138141586, 138140526	BI150149	56615	32	glutathione transferase activity glutathione transferase activity glutathione transferase activity glutathione peroxidase activity mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial inner membrane peroxisomal membrane endoplasmic reticulum glutathione metabolic process response to xenobiotic stimulus response to organonitrogen compound membrane transferase activity response to lipopolysaccharide glutathione transport identical protein binding glutathione binding apical part of cell cellular response to lipid hydroperoxide	00480 00980 00982
1420330_at	Clec4e	C-type lectin domain family 4, member e	6	-123281788	NM_019948	56619	103	positive regulation of cytokine production pattern recognition receptor signaling pathway T cell differentiation involved in immune response immune system process calcium ion binding protein binding plasma membrane immune response external side of plasma membrane membrane carbohydrate binding carbohydrate binding phagocytic vesicle membrane signaling receptor activity Fc-gamma receptor signaling pathway pattern recognition receptor activity pattern recognition receptor activity pattern recognition receptor activity defense response to bacterium cell projection innate immune response innate immune response metal ion binding glycolipid binding antifungal innate immune response antifungal innate immune response
1425951_a_at	Clec4n	C-type lectin domain family 4, member n	6	123229842	AF240358	56620	96	positive regulation of cytokine production response to yeast detection of yeast stimulatory C-type lectin receptor signaling pathway adaptive immune response immune system process calcium ion binding protein binding mannose binding plasma membrane plasma membrane external side of plasma membrane membrane carbohydrate binding carbohydrate binding carbohydrate binding pattern recognition receptor activity pattern recognition receptor activity positive regulation of canonical NF-kappaB signal transduction innate immune response metal ion binding positive regulation of peptidyl-tyrosine phosphorylation defense response to fungus antifungal innate immune response antifungal innate immune response positive regulation of intracellular signal transduction positive regulation of T-helper 17 type immune response
1420699_at	Clec7a	C-type lectin domain family 7, member a	6	-129461590, -129461590	NM_020008	56644	251	cell activation opsonin binding (1->3)-beta-D-glucan binding (1->3)-beta-D-glucan binding (1->3)-beta-D-glucan binding (1->3)-beta-D-glucan immune receptor activity response to yeast detection of yeast stimulatory C-type lectin receptor signaling pathway response to molecule of fungal origin leukocyte activation involved in immune response immune system process positive regulation of cytokine production involved in immune response positive regulation of dendritic cell cytokine production positive regulation of dendritic cell cytokine production cell surface pattern recognition receptor signaling pathway protein binding cytoplasm plasma membrane plasma membrane phagocytosis, recognition phagocytosis, recognition phagocytosis, recognition phagocytosis, engulfment inflammatory response cell recognition positive regulation of cell population proliferation positive regulation of cell population proliferation external side of plasma membrane cell surface cell surface positive regulation of gene expression membrane detection of fungus detection of fungus carbohydrate binding polysaccharide binding positive regulation of cell migration positive regulation of cell migration positive regulation of protein-containing complex assembly detection of molecule of fungal origin detection of molecule of fungal origin detection of molecule of fungal origin positive regulation of type II interferon production positive regulation of interleukin-1 beta production positive regulation of interleukin-10 production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-2 production positive regulation of interleukin-2 production positive regulation of interleukin-23 production positive regulation of interleukin-6 production positive regulation of interleukin-6 production positive regulation of interleukin-8 production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of tumor necrosis factor production positive regulation of stress-activated MAPK cascade positive regulation of superoxide anion generation pattern recognition receptor activity pattern recognition receptor activity pattern recognition receptor activity pattern recognition receptor activity identical protein binding regulation of canonical NF-kappaB signal transduction positive regulation of canonical NF-kappaB signal transduction positive regulation of cysteine-type endopeptidase activity involved in apoptotic process innate immune response positive regulation of nitric oxide biosynthetic process metal ion binding positive regulation of peptidyl-tyrosine phosphorylation positive regulation of phagocytosis positive regulation of phagocytosis positive regulation of phagocytosis positive regulation of calcium-mediated signaling positive regulation of DNA-binding transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of lymphocyte activation positive regulation of lymphocyte activation positive regulation of killing of cells of another organism positive regulation of killing of cells of another organism positive regulation of respiratory burst antifungal innate immune response antifungal innate immune response regulation of calcineurin-NFAT signaling cascade cellular response to molecule of fungal origin cellular response to molecule of fungal origin cellular response to molecule of fungal origin positive regulation of monocyte chemotactic protein-1 production positive regulation of wound healing positive regulation of wound healing cell-cell adhesion positive regulation of cytokine production involved in inflammatory response positive regulation of cytokine production involved in inflammatory response positive regulation of cell maturation positive regulation of T-helper 17 type immune response	04145
1437270_a_at	Clcf1	cardiotrophin-like cytokine factor 1	19	4214388, 4214237	BB825816	56708	35	positive regulation of immunoglobulin production positive regulation of type 2 immune response signaling receptor binding cytokine activity cytokine activity cytokine activity ciliary neurotrophic factor receptor binding ciliary neurotrophic factor receptor binding protein binding extracellular region extracellular region extracellular space cell surface receptor signaling pathway receptor signaling pathway via JAK-STAT receptor signaling pathway via JAK-STAT positive regulation of cell population proliferation B cell differentiation positive regulation of B cell proliferation positive regulation of B cell proliferation positive regulation of tyrosine phosphorylation of STAT protein positive regulation of tyrosine phosphorylation of STAT protein positive regulation of tyrosine phosphorylation of STAT protein negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process positive regulation of isotype switching to IgE isotypes positive regulation of astrocyte differentiation regulation of inflammatory response positive regulation of corticotropin-releasing hormone secretion regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of ERK1 and ERK2 cascade CRLF-CLCF1 complex CRLF-CLCF1 complex CRLF-CLCF1 complex CNTFR-CLCF1 complex CNTFR-CLCF1 complex negative regulation of motor neuron apoptotic process	04060 04630
1423323_at	Tacstd2	tumor-associated calcium signal transducer 2	6	-67534058	AV241768	56753	35	extracellular space extracellular space nucleus nucleus plasma membrane basal plasma membrane negative regulation of epithelial cell migration membrane lateral plasma membrane regulation of epithelial cell proliferation negative regulation of stress fiber assembly ureteric bud morphogenesis negative regulation of branching involved in ureteric bud morphogenesis negative regulation of substrate adhesion-dependent cell spreading negative regulation of ruffle assembly negative regulation of cell motility positive regulation of stem cell differentiation positive regulation of stem cell differentiation
1440315_at	Mbnl1	muscleblind like splicing regulator 1	3	60501178, 60472829	BB202204	56758	102	alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome regulatory region RNA binding in utero embryonic development RNA binding RNA binding double-stranded RNA binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm cytoplasm cytosol mRNA splice site recognition mRNA processing nervous system development skeletal muscle tissue development RNA splicing cytoplasmic stress granule embryonic limb morphogenesis regulation of RNA splicing regulation of RNA splicing myoblast differentiation metal ion binding
1449738_s_at	Supt20	SPT20 SAGA complex component	3	54692814, 54695122, 54693104	C80158	56790	29	SAGA complex SAGA complex transcription coregulator activity transcription coregulator activity regulation of DNA repair regulation of transcription by RNA polymerase II multicellular organism development gastrulation regulation of RNA splicing positive regulation of gluconeogenesis positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II SAGA-type complex
1440284_at	Stap1	signal transducing adaptor family member 1	5	86071745	AI506066	56792	27	phosphotyrosine residue binding transmembrane receptor protein tyrosine kinase adaptor activity macrophage colony-stimulating factor receptor binding protein binding nucleus nucleoplasm cytoplasm mitochondrion cytosol transmembrane receptor protein tyrosine kinase signaling pathway transmembrane receptor protein tyrosine kinase signaling pathway response to bacterium positive regulation of gene expression negative regulation of macrophage chemotaxis protein kinase binding protein kinase binding myeloid cell differentiation protein tyrosine kinase activator activity protein-macromolecule adaptor activity receptor tyrosine kinase binding protein-containing complex centriolar satellite signaling adaptor activity signaling adaptor activity negative regulation of phosphorylation positive regulation of B cell receptor signaling pathway positive regulation of B cell receptor signaling pathway positive regulation of phagocytosis, engulfment cellular response to lipopolysaccharide negative regulation of ruffle assembly negative regulation of macrophage colony-stimulating factor signaling pathway positive regulation of microglial cell activation negative regulation of microglial cell migration positive regulation of microglial cell mediated cytotoxicity
1436959_x_at	Nsmf	NMDA receptor synaptonuclear signaling and neuronal migration factor	2	25054378	BB311061	56876	39	euchromatin protein binding nucleus nucleus nucleus nuclear envelope nucleoplasm cytoplasm cytoplasm cytoplasm cytoskeleton plasma membrane postsynaptic density membrane nuclear matrix dendrite cortical cytoskeleton nuclear membrane positive regulation of protein dephosphorylation cell projection neuron projection dendritic spine perikaryon regulation of neuron apoptotic process synapse regulation of neuronal synaptic plasticity calcium-dependent protein binding regulation of dendrite morphogenesis cellular response to amino acid stimulus cellular response to electrical stimulus cellular response to gonadotropin stimulus apical dendrite postsynapse glutamatergic synapse postsynapse to nucleus signaling pathway regulation of neuron migration positive regulation of neuron migration positive regulation of neuron migration
1425890_at	Ly6i	lymphocyte antigen 6 family member I	15	-74979533	AF232024	57248	13	plasma membrane plasma membrane membrane acetylcholine receptor inhibitor activity acetylcholine receptor binding acetylcholine receptor signaling pathway side of membrane
1449015_at	Retnla	resistin like alpha	16	48842608	NM_020509	57262	89	hormone activity extracellular region extracellular space
1423108_at	Slc25a20	solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20	9	108662135	AV008091	57279	36	in utero embryonic development mitochondrion mitochondrion mitochondrial envelope mitochondrial inner membrane cytosol mitochondrial transport lipid transport acyl carnitine transmembrane transporter activity acyl carnitine transmembrane transporter activity membrane carnitine transmembrane transport carnitine transmembrane transport
1426100_a_at	Tk2	thymidine kinase 2, mitochondrial	8	-104226690	AF105217	57813	37	nucleotide binding deoxycytidine kinase activity deoxycytidine kinase activity thymidine kinase activity thymidine kinase activity thymidine kinase activity ATP binding cytoplasm mitochondrion mitochondrion mitochondrion mitochondrion mitochondrial inner membrane nucleobase-containing compound metabolic process mitochondrial DNA replication deoxyribonucleotide metabolic process kinase activity phosphorylation transferase activity deoxynucleoside kinase activity deoxynucleoside kinase activity mitochondrial DNA metabolic process deoxycytidine metabolic process thymidine metabolic process DNA biosynthetic process	00240 00983 01100
1421479_at	Zfp318	zinc finger protein 318	17	46383765	NM_021346	57908	28	nucleic acid binding protein binding nucleus nucleoplasm nucleoplasm cytosol zinc ion binding protein homodimerization activity negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription metal ion binding protein heterodimerization activity meiotic cell cycle
1423182_at	Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	11	61142483, 61126754	AK004668	57916	86	B cell homeostasis B cell homeostasis B cell homeostasis hematopoietic progenitor cell differentiation hematopoietic progenitor cell differentiation adaptive immune response immune system process plasma membrane external side of plasma membrane membrane negative regulation of B cell proliferation negative regulation of B cell proliferation	04060 04672 05340
1456261_at	Sh3kbp1	SH3-domain kinase binding protein 1	X	159942692, 159627271, 159840467, 159708600, 159627283	BB766215	58194	54	protein binding cytoplasm cytoskeleton cell-cell junction endocytosis apoptotic process cytoskeleton organization actin filament organization regulation of cell shape membrane cell migration cell migration SH3 domain binding endocytic vesicle cytoplasmic vesicle ubiquitin protein ligase binding neuron projection synapse positive regulation of B cell activation molecular adaptor activity ubiquitin-dependent endocytosis anchoring junction	04144
1429947_a_at	Zbp1	Z-DNA binding protein 1	2	-173206611, -173213735	AK008179	58203	85	activation of innate immune response activation of innate immune response immune system process DNA binding DNA binding DNA binding left-handed Z-DNA binding RNA binding double-stranded RNA binding double-stranded RNA adenosine deaminase activity protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytosol cytosol apoptotic process programmed cell death identical protein binding positive regulation of apoptotic process positive regulation of apoptotic process innate immune response regulation of inflammatory response positive regulation of inflammatory response defense response to fungus defense response to virus defense response to virus defense response to virus positive regulation of type I interferon-mediated signaling pathway positive regulation of type I interferon-mediated signaling pathway positive regulation of necroptotic process positive regulation of necroptotic process positive regulation of necroptotic process pyroptosis antiviral innate immune response regulation of interleukin-1-mediated signaling pathway	04623
1452966_at	Bcl11b	B cell leukemia/lymphoma 11B	12	-107910402	AK020296	58208	764	RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific keratinocyte development epithelial cell morphogenesis DNA-binding transcription factor activity protein binding intracellular anatomical structure nucleus nucleus transcription by RNA polymerase II transcription by RNA polymerase II transcription by RNA polymerase II apoptotic process axonogenesis negative regulation of cell population proliferation post-embryonic development regulation of gene expression regulation of keratinocyte proliferation SWI/SNF complex SWI/SNF complex regulation of lipid metabolic process striatal medium spiny neuron differentiation commitment of neuronal cell to specific neuron type in forebrain central nervous system neuron differentiation post-embryonic camera-type eye development T cell differentiation in thymus T cell receptor V(D)J recombination hematopoietic stem cell migration odontogenesis of dentin-containing tooth neuron projection positive T cell selection sequence-specific DNA binding skin development regulation of neuron differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II alpha-beta T cell differentiation metal ion binding thymus development T cell apoptotic process negative regulation of T cell apoptotic process thymocyte apoptotic process negative regulation of thymocyte apoptotic process olfactory bulb axon guidance lymphoid lineage cell migration into thymus sequence-specific double-stranded DNA binding
1447284_at	Trem1	triggering receptor expressed on myeloid cells 1	17	48232738	BB784999	58217	126	cytokine production positive regulation of cell-matrix adhesion adaptive immune response cytokine production involved in immune response cytokine production involved in immune response immune system process transmembrane signaling receptor activity extracellular space plasma membrane cell surface positive regulation of cardiac muscle cell apoptotic process positive regulation of macrophage chemotaxis membrane neutrophil chemotaxis neutrophil chemotaxis chemokine production chemokine production innate immune response neutrophil-mediated killing of gram-negative bacterium neutrophil-mediated killing of gram-negative bacterium neutrophil extravasation scaffold protein binding receptor decoy activity neutrophil migration
1460271_at	Trem3	triggering receptor expressed on myeloid cells 3	17	48247728	NM_021407	58218	23	cytokine production cytokine production involved in immune response cytokine production involved in immune response protein binding plasma membrane membrane cell migration neutrophil chemotaxis neutrophil chemotaxis chemokine production chemokine production positive regulation of innate immune response neutrophil-mediated killing of gram-negative bacterium neutrophil-mediated killing of gram-negative bacterium neutrophil extravasation
1421977_at	Mmp19	matrix metallopeptidase 19	10	128790909, 128790954	AF153199	58223	33	angiogenesis metalloendopeptidase activity metalloendopeptidase activity metalloendopeptidase activity extracellular region extracellular region extracellular space extracellular space plasma membrane proteolysis multicellular organism development peptidase activity metallopeptidase activity zinc ion binding membrane hydrolase activity cell differentiation extracellular matrix organization collagen catabolic process collagen catabolic process extracellular matrix metal ion binding side of membrane
1460174_at	Dexi	dexamethasone-induced transcript	16	-10530206	NM_021428	58239	17	molecular_function cellular_component biological_process
1416799_at	Trpm7	transient receptor potential cation channel, subfamily M, member 7	2	-126791557	AV320241	58800	146	nucleotide binding ruffle actin binding protein kinase activity protein serine/threonine kinase activity monoatomic ion channel activity monoatomic cation channel activity calcium channel activity calcium channel activity calcium channel activity protein binding ATP binding plasma membrane protein phosphorylation monoatomic ion transport calcium ion transport calcium ion transport calcium ion transport memory intracellular magnesium ion homeostasis programmed cell death membrane kinase activity phosphorylation calcium-dependent cell-matrix adhesion transferase activity myosin binding synaptic vesicle membrane actomyosin structure organization monoatomic ion transmembrane transport neuronal cell body positive regulation of apoptotic process varicosity protein autophosphorylation metal ion binding protein tetramerization transmembrane transport necroptotic process calcium ion transmembrane transport monoatomic cation transmembrane transport
1420641_a_at	Sqor	sulfide quinone oxidoreductase	2	122771712, 122781998, 122765358	AF174535	59010	26	mitochondrion mitochondrion mitochondrial inner membrane oxidoreductase activity quinone binding sulfide oxidation, using sulfide:quinone oxidoreductase sulfide oxidation, using sulfide:quinone oxidoreductase sulfide:quinone oxidoreductase activity sulfide:quinone oxidoreductase activity FAD binding glutathione-dependent sulfide quinone oxidoreductase activity
1418530_at	Nup160	nucleoporin 160	2	90677214	NM_021512	59015	31	kinetochore nucleus nuclear envelope nuclear pore nuclear pore nuclear pore nuclear pore mRNA export from nucleus mRNA export from nucleus nucleocytoplasmic transport protein transport structural constituent of nuclear pore structural constituent of nuclear pore structural constituent of nuclear pore nuclear pore outer ring mRNA transport nephron development	03013
1417190_at	Nampt	nicotinamide phosphoribosyltransferase	12	32820334	AW989410	59027	189	nucleotide binding microglial cell activation cytokine activity extracellular region extracellular space nucleus cytoplasm cytosol circadian rhythm NAD biosynthetic process NAD biosynthetic process negative regulation of autophagy regulation of lung blood pressure nuclear speck transferase activity glycosyltransferase activity pyridine nucleotide biosynthetic process cell junction circadian regulation of gene expression identical protein binding identical protein binding positive regulation of transcription by RNA polymerase II nicotinamide phosphoribosyltransferase activity nicotinamide phosphoribosyltransferase activity nicotinamide phosphoribosyltransferase activity rhythmic process positive regulation of smooth muscle cell proliferation positive regulation of nitric-oxide synthase biosynthetic process heterocyclic compound binding negative regulation of cellular senescence	00760
1417710_at	Mettl9	methyltransferase like 9	7	121034444	NM_021554	59052	19	mitochondrion endoplasmic reticulum methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity transferase activity methylation protein-L-histidine N-pros-methyltransferase activity protein-L-histidine N-pros-methyltransferase activity
1423467_at	Ms4a4b	membrane-spanning 4-domains, subfamily A, member 4B	19	11443557	BB199001	60361	20	Golgi apparatus plasma membrane plasma membrane
1417719_at	Sap30	sin3 associated polypeptide	8	-57482701	NM_021788	60406	31	histone deacetylase complex histone deacetylase complex negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II DNA binding transcription coregulator activity transcription corepressor activity protein binding nucleus nucleus nucleoplasm nucleoplasm regulation of DNA-templated transcription negative regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway skeletal muscle cell differentiation metal ion binding modulation by host of symbiont transcription Sin3-type complex negative regulation of stem cell population maintenance positive regulation of stem cell population maintenance
1419043_a_at	Iigp1	interferon inducible GTPase 1	18	60376028, 60373615	BM239828	60440	45	nucleotide binding immune system process GTPase activity GTPase activity GTPase activity protein binding GTP binding nucleus cytoplasm endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane Golgi apparatus defense response response to bacterium regulation of autophagy membrane hydrolase activity GDP binding cytokine-mediated signaling pathway symbiont-containing vacuole membrane cellular response to interferon-beta cellular response to interferon-beta identical protein binding identical protein binding defense response to protozoan innate immune response defense response to Gram-negative bacterium
1422478_a_at	Acss2	acyl-CoA synthetase short-chain family member 2	2	155518042	NM_019811	60525	51	nucleotide binding chromatin binding transcription coactivator activity acetate-CoA ligase activity acetate-CoA ligase activity acetate-CoA ligase activity acetate-CoA ligase activity protein binding ATP binding nucleus nucleus cytoplasm cytoplasm cytosol cytosol acetyl-CoA biosynthetic process acetyl-CoA biosynthetic process lipid metabolic process long-term memory lipid biosynthetic process ligase activity acetate biosynthetic process propionate biosynthetic process propionate-CoA ligase activity	00010 00620 00640 01100
1419714_at	Cd274	CD274 antigen	19	29367437	NM_021893	60533	509	adaptive immune response immune system process positive regulation of tolerance induction to tumor cell transcription coactivator activity protein binding nucleoplasm endosome plasma membrane immune response immune response signal transduction cell surface receptor signaling pathway cell surface receptor signaling pathway external side of plasma membrane external side of plasma membrane cell surface actin cytoskeleton membrane positive regulation of cell migration T cell costimulation T cell costimulation early endosome membrane negative regulation of type II interferon production negative regulation of interleukin-10 production positive regulation of interleukin-10 production response to cytokine TRIF-dependent toll-like receptor signaling pathway positive regulation of T cell proliferation positive regulation of T cell proliferation negative regulation of T cell proliferation negative regulation of T cell proliferation negative regulation of activated T cell proliferation recycling endosome membrane extracellular exosome cellular response to lipopolysaccharide negative regulation of tumor necrosis factor superfamily cytokine production positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of CD8-positive, alpha-beta T cell activation	04514
1451370_at	Ccdc107	coiled-coil domain containing 107	4	43493364	BC027414	622404	12	molecular_function cellular_component biological_process membrane
1441887_x_at	Gm6377	predicted gene 6377	X	109196755	BB548587	622976	11	molecular_function cellular_component regulation of lysosomal lumen pH
1438238_at	2010315B03Rik	RIKEN cDNA 2010315B03 gene	9	-124291803	BB744779	630836	10	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity regulation of transcription by RNA polymerase II
1426607_at	Tmem267	transmembrane protein 267	13	119488472, 119488085	BG068672	633640	13	molecular_function cellular_component biological_process membrane
1449976_a_at	Gpr35	G protein-coupled receptor 35	1	92978902, 92973118, 92975346	NM_022320	64095	42	G protein-coupled receptor activity G protein-coupled receptor activity chemokine receptor activity plasma membrane plasma membrane cytoskeleton organization signal transduction G protein-coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration membrane positive regulation of Rho protein signal transduction macrophage chemotaxis chemokine-mediated signaling pathway negative regulation of voltage-gated calcium channel activity negative regulation of neuronal action potential	04080
1418206_at	Sdf2l1	stromal cell-derived factor 2-like 1	16	-17130137	NM_022324	64136	21	endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum chaperone complex response to endoplasmic reticulum stress ERAD pathway regulation of apoptotic process chaperone cofactor-dependent protein refolding protein-folding chaperone binding ATPase binding misfolded protein binding cellular response to misfolded protein protein folding chaperone complex
1435517_x_at	Ralb	v-ral simian leukemia viral oncogene B	1	-119470304	BB465250	64143	33	nucleotide binding regulation of exocyst assembly positive regulation of protein phosphorylation GTPase activity GTPase activity G protein activity GTP binding GTP binding plasma membrane plasma membrane apoptotic process cell cycle signal transduction Ras protein signal transduction cellular response to starvation membrane hydrolase activity GDP binding GDP binding midbody receptor internalization ubiquitin protein ligase binding negative regulation of protein binding positive regulation of protein binding positive regulation of epidermal growth factor receptor signaling pathway ATPase binding cell division regulation of exocyst localization cellular response to exogenous dsRNA positive regulation of protein serine/threonine kinase activity positive regulation of autophagosome assembly	05200 05212
1416863_at	Abhd8	abhydrolase domain containing 8	8	-71456699	NM_022419	64296	18	catalytic activity hydrolase activity
1418797_at	Ms4a8a	membrane-spanning 4-domains, subfamily A, member 8A	19	-11067470	NM_022430	64381	14	plasma membrane plasma membrane cell surface receptor signaling pathway membrane
1417527_at	Ap3m2	adaptor-related protein complex 3, mu 2 subunit	8	-22787353	BC027301	64933	26	early endosome Golgi apparatus intracellular protein transport endocytosis anterograde axonal transport protein transport membrane synaptic vesicle coating vesicle-mediated transport AP-3 adaptor complex clathrin adaptor complex cytoplasmic vesicle cytoplasmic vesicle clathrin-coated vesicle cargo loading, AP-3-mediated synaptic vesicle recycling intracellular transport anterograde synaptic vesicle transport	04142
1437236_a_at	Zfp110	zinc finger protein 110	7	12834760	AV263718	65020	33	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding chromatin binding neurotrophin p75 receptor binding protein binding nucleus cytoplasm cytosol chromatin remodeling regulation of DNA-templated transcription regulation of transcription by RNA polymerase II apoptotic process sequence-specific DNA binding regulation of JNK cascade metal ion binding neuron apoptotic process extrinsic apoptotic signaling pathway retinal cell apoptotic process sequence-specific double-stranded DNA binding	04722
1420697_at	Slc15a3	solute carrier family 15, member 3	19	10842543	NM_023044	65221	18	immune system process lysosome lysosomal membrane lysosomal membrane lysosomal membrane endosome oligopeptide transport endosome membrane protein transport symporter activity peptidoglycan transmembrane transporter activity peptide transport peptidoglycan transport membrane transmembrane transporter activity intracellular membrane-bounded organelle innate immune response transmembrane transport positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway dipeptide transmembrane transporter activity dipeptide transmembrane transporter activity dipeptide import across plasma membrane dipeptide import across plasma membrane
1415682_at	Xpo7	exportin 7	14	-70662125, -70662125	NM_023045	65246	34	nuclear export signal receptor activity nuclear export signal receptor activity protein binding nucleus nuclear pore nuclear pore cytoplasm cytoplasm protein export from nucleus protein export from nucleus intracellular protein transport nucleocytoplasmic transport protein transport small GTPase binding nuclear transport
1440845_at	Tmem243	transmembrane protein 243, mitochondrial	5	9100736	BB323696	652925	11	molecular_function cellular_component biological_process
1448263_a_at	Cndp2	CNDP dipeptidase 2	18	-84667464, -84667464	NM_023149	66054	41	carboxypeptidase activity nucleoplasm cytoplasm cytosol cytosol proteolysis proteolysis proteolysis peptidase activity metallopeptidase activity hydrolase activity dipeptidase activity dipeptidase activity dipeptidase activity metal ion binding metallodipeptidase activity alanylglutamate dipeptidase activity
1447678_at	Hsd17b14	hydroxysteroid (17-beta) dehydrogenase 14	7	45554927	BB399925	66065	14	estradiol 17-beta-dehydrogenase [NAD(P)] activity estradiol 17-beta-dehydrogenase [NAD(P)] activity cytosol cytosol steroid catabolic process steroid catabolic process identical protein binding testosterone 17-beta-dehydrogenase (NADP+) activity
1419103_a_at	Abhd6	abhydrolase domain containing 6	14	8002887, 8002965	NM_025341	66082	41	catalytic activity phospholipase activity mitochondrion mitochondrion lysosome lysosomal membrane endosome lipid metabolic process phospholipid catabolic process membrane hydrolase activity negative regulation of cell migration late endosome membrane AMPA glutamate receptor complex postsynaptic membrane acylglycerol catabolic process acylglycerol catabolic process acylglycerol catabolic process positive regulation of lipid biosynthetic process acylglycerol lipase activity acylglycerol lipase activity acylglycerol lipase activity acylglycerol lipase activity monoacylglycerol catabolic process long-term synaptic depression glutamatergic synapse glutamatergic synapse GABA-ergic synapse regulation of retrograde trans-synaptic signaling by endocanabinoid regulation of retrograde trans-synaptic signaling by endocanabinoid negative regulation of cold-induced thermogenesis regulation of endocannabinoid signaling pathway lysobisphosphatidic acid metabolic process
1428797_at	Setd6	SET domain containing 6	8	95715912	AK010304	66083	22	protein binding nucleus nucleus nucleoplasm cytosol methyltransferase activity protein-lysine N-methyltransferase activity protein-lysine N-methyltransferase activity transferase activity peptidyl-lysine methylation peptidyl-lysine monomethylation peptidyl-lysine monomethylation stem cell population maintenance negative regulation of NF-kappaB transcription factor activity methylation stem cell differentiation regulation of inflammatory response NF-kappaB binding S-adenosyl-L-methionine binding
1434484_at	Wfdc21	WAP four-disulfide core domain 21	11	83746939	AV006463	66107	13	serine-type endopeptidase inhibitor activity extracellular region extracellular space extracellular space enzyme activator activity antibacterial humoral response peptidase inhibitor activity response to lipopolysaccharide response to tumor necrosis factor innate immune response white fat cell differentiation
1423754_at	Ifitm3	interferon induced transmembrane protein 3	7	-141009589	BC010291	66141	97	immune system process nucleus cytoplasm lysosome lysosomal membrane endosome endoplasmic reticulum plasma membrane plasma membrane plasma membrane receptor-mediated endocytosis negative regulation of cell population proliferation response to virus cell surface membrane cytoplasmic vesicle early endosome membrane protein-containing complex response to type II interferon response to interferon-alpha response to interferon-beta negative regulation of viral genome replication innate immune response apical part of cell negative regulation of viral entry into host cell negative regulation of viral entry into host cell defense response to virus defense response to virus defense response to virus defense response to virus type I interferon-mediated signaling pathway type I interferon-mediated signaling pathway
1428883_at	Maco1	macoilin 1	4	-134802760, -134802759	AK003528	66146	25	nucleus endoplasmic reticulum chemotaxis brain development microtubule binding membrane neuronal signal transduction neuronal signal transduction axon rough endoplasmic reticulum membrane rough endoplasmic reticulum membrane nuclear membrane nuclear membrane neuron projection neuron projection terminus synapse
1429520_a_at	Acer3	alkaline ceramidase 3	7	-98213809, -98213809	BE573407	66190	19	Golgi membrane calcium ion binding endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus lipid metabolic process sphingolipid metabolic process ceramide metabolic process inflammatory response zinc ion binding positive regulation of cell population proliferation membrane hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides N-acylsphingosine amidohydrolase activity myelination regulation of programmed cell death sphingosine biosynthetic process sphingosine biosynthetic process ceramide catabolic process ceramide catabolic process metal ion binding phytoceramidase activity phytoceramidase activity phytoceramidase activity phytosphingosine biosynthetic process phytosphingosine biosynthetic process dihydroceramidase activity ceramidase activity	00600
1448919_at	Cd302	CD302 antigen	2	-60251992	NM_025422	66205	16	cytoplasm cell cortex phagocytosis external side of plasma membrane membrane filopodium carbohydrate binding signaling receptor activity cell projection
1424683_at	Retreg1	reticulophagy regulator 1	15	25933551, 25940825, 25843297, 25940701, 25942678	BC019494	66270	34	mitophagy protein binding nucleolus endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane Golgi apparatus cis-Golgi network autophagy endoplasmic reticulum organization membrane nuclear body sensory perception of pain collagen catabolic process negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process protein self-association white fat cell differentiation reticulophagy reticulophagy reticulophagy reticulophagy endoplasmic reticulum-autophagosome adaptor activity
1438413_at	Senp7	SUMO1/sentrin specific peptidase 7	16	56075403, 56057529, 56075403, 56075479	AV231698	66315	28	immune system process protein binding nucleus nucleus cytoplasm cytoplasm proteolysis peptidase activity cysteine-type peptidase activity hydrolase activity protein desumoylation protein desumoylation innate immune response SUMO-specific endopeptidase activity SUMO-specific endopeptidase activity antiviral innate immune response
1416775_at	Dmac2	distal membrane arm assembly complex 2	7	25619492, 25619413	NM_025504	66349	13	mitochondrion mitochondrial respiratory chain complex I SCF ubiquitin ligase complex SCF-dependent proteasomal ubiquitin-dependent protein catabolic process mitochondrial respiratory chain complex I assembly mitochondrial respiratory chain complex I assembly
1426440_at	Dhrs7	dehydrogenase/reductase 7	12	-72650352	AK009385	66375	19	carbonyl reductase (NADPH) activity endoplasmic reticulum endoplasmic reticulum membrane membrane oxidoreductase activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor retinol metabolic process NADP-retinol dehydrogenase activity
1435346_at	Ccdc82	coiled-coil domain containing 82	9	13246955	BE352816	66396	12	molecular_function nucleus biological_process
1417138_s_at	Polr2e	polymerase (RNA) II (DNA directed) polypeptide E	10	-80035952	NM_025554	66420	24	DNA-directed RNA polymerase complex RNA polymerase I activity RNA polymerase II activity RNA polymerase III activity DNA binding DNA-directed 5'-3' RNA polymerase activity nucleus nucleoplasm nucleoplasm RNA polymerase II, core complex RNA polymerase II, core complex RNA polymerase III complex RNA polymerase III complex RNA polymerase I complex RNA polymerase I complex DNA-templated transcription transcription elongation by RNA polymerase I transcription by RNA polymerase II transcription by RNA polymerase II tRNA transcription by RNA polymerase III RPAP3/R2TP/prefoldin-like complex	00230 00240 01100 03020 05016
1455170_at	2810001G20Rik	RIKEN cDNA 2810001G20 gene	11	64079483	BB250227	66456	12	molecular_function cellular_component biological_process
1417075_at	Fam136a	family with sequence similarity 136, member A	6	86365645, 86365470	NM_025591	66488	18	molecular_function cytoplasm cytoplasm mitochondrion biological_process
1436153_a_at	Zmynd11	zinc finger, MYND domain containing 11	13	-9684835, -9684835, -9684835, -9684835	BB561053	66505	27	DNA binding double-stranded DNA binding transcription corepressor activity protein binding nucleus nucleus nucleoplasm chromosome chromatin organization zinc ion binding zinc ion binding regulation of signal transduction regulation of transcription elongation by RNA polymerase II regulation of transcription elongation by RNA polymerase II methylated histone binding methylated histone binding methylated histone binding histone binding negative regulation of canonical NF-kappaB signal transduction negative regulation of JNK cascade metal ion binding defense response to virus negative regulation of extrinsic apoptotic signaling pathway
1425193_at	Sppl2a	signal peptide peptidase like 2A	2	-126890394	BC026578	66552	34	lysosome lysosomal membrane lysosomal membrane endosome late endosome plasma membrane proteolysis membrane protein ectodomain proteolysis peptidase activity membrane hydrolase activity Golgi-associated vesicle membrane Golgi-associated vesicle membrane membrane protein intracellular domain proteolysis late endosome membrane membrane protein proteolysis membrane protein proteolysis membrane protein proteolysis aspartic endopeptidase activity, intramembrane cleaving aspartic endopeptidase activity, intramembrane cleaving protein homodimerization activity intracellular membrane-bounded organelle regulation of immune response regulation of immune response lumenal side of endoplasmic reticulum membrane cytoplasmic side of endoplasmic reticulum membrane
1437041_at	Pnisr	PNN interacting serine/arginine-rich	4	21848047	BB120903	66625	22	molecular_function nucleus nucleoplasm cytosol plasma membrane biological_process nuclear speck nuclear speck presynaptic active zone
1438442_at	Sike1	suppressor of IKBKE 1	3	102995739	AI450236	66641	14	molecular_function cytoplasm biological_process protein kinase binding small GTPase binding	04622
1434662_at	Atg4a	autophagy related 4A, cysteine peptidase	X	140956906, 140953844	BM237732	666468	16	autophagosome assembly autophagosome assembly mitophagy cysteine-type endopeptidase activity cytoplasm C-terminal protein lipidation proteolysis autophagy cysteine-type peptidase activity protein processing protein-phosphatidylethanolamide deconjugating activity protein-phosphatidylethanolamide deconjugating activity piecemeal microautophagy of the nucleus aggrephagy protein delipidation protein delipidation	04140
1442219_at	Gm8369	predicted gene 8369	19	11492037	BB218965	666926	9	molecular_function Golgi apparatus plasma membrane biological_process
1425738_at	Igkv3-12	immunoglobulin kappa variable 3-12	6		M35669	667914	3	immunoglobulin production extracellular space extracellular space immune response monomeric IgA immunoglobulin complex secretory IgA immunoglobulin complex pentameric IgM immunoglobulin complex
1418778_at	Mcub	mitochondrial calcium uniporter dominant negative beta subunit	3	-129914959	NM_025779	66815	23	protein binding nucleoplasm mitochondrion mitochondrion mitochondrial inner membrane monoatomic ion transport calcium ion transport mitochondrial calcium ion transmembrane transport membrane calcium channel inhibitor activity calcium channel inhibitor activity calcium channel complex calcium import into the mitochondrion intracellular membrane-bounded organelle mitochondrial calcium ion homeostasis mitochondrial calcium ion homeostasis uniplex complex uniplex complex
1455817_x_at	Zxdb	zinc finger, X-linked, duplicated B	X	94724568	AI661029	668166	11	transcription coregulator activity transcription coactivator activity nucleus nucleus regulation of transcription by RNA polymerase II metal ion binding C2H2 zinc finger domain binding
1435002_at	Zfp507	zinc finger protein 507	7	-35772345	BM249415	668501	22	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding nucleus regulation of DNA-templated transcription metal ion binding
1454650_at	Trim35	tripartite motif-containing 35	14	66297024	BQ175280	66854	32	protein binding nucleus cytoplasm cytoplasm apoptotic process zinc ion binding negative regulation of cell population proliferation protein ubiquitination transferase activity myeloid cell apoptotic process positive regulation of myeloid cell apoptotic process positive regulation of apoptotic process positive regulation of apoptotic process suppression of viral release by host innate immune response innate immune response negative regulation of mitotic cell cycle metal ion binding ubiquitin protein ligase activity
1460672_at	2410002F23Rik	RIKEN cDNA 2410002F23 gene	7	44246721	BC016099	668661	18	molecular_function cellular_component Golgi apparatus biological_process response to virus
1429473_at	Zfp869	zinc finger protein 869	8	-69705136, -69705137	AV292561	66869	18	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific nucleus nucleus regulation of transcription by RNA polymerase II retrotransposon silencing
1417978_at	Eif4e3	eukaryotic translation initiation factor 4E member 3	6	-99625136	BC027014	66892	23	RNA 7-methylguanosine cap binding RNA binding translation initiation factor activity translation initiation factor activity translation translational initiation translational initiation regulation of translation eukaryotic translation initiation factor 4F complex
1451346_at	Mtap	methylthioadenosine phosphorylase	4	89137369	BG075139	66902	38	catalytic activity nucleus nucleoplasm cytoplasm cytosol cytosol purine ribonucleoside salvage nucleoside metabolic process transferase activity glycosyltransferase activity pentosyltransferase activity S-methyl-5-thioadenosine phosphorylase activity S-methyl-5-thioadenosine phosphorylase activity L-methionine salvage from methylthioadenosine methylation	00270 01100
1448689_at	Rras2	related RAS viral (r-ras) oncogene 2	7	-114046781	NM_025846	66922	49	nucleotide binding GTPase activity GTPase activity protein binding GTP binding GTP binding intracellular anatomical structure Golgi apparatus plasma membrane plasma membrane signal transduction Ras protein signal transduction Ras protein signal transduction membrane cell migration hydrolase activity GDP binding Schwann cell migration positive regulation of Schwann cell migration	04010 04530 04810
1423986_a_at	Shisa5	shisa family member 5	9	109054865, 109038566, 109051156, 109051095, 109040413, 109052853	BC010238	66940	22	nucleus nuclear envelope endoplasmic reticulum endoplasmic reticulum apoptotic process membrane intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator WW domain binding intrinsic apoptotic signaling pathway by p53 class mediator	04115
1439387_x_at	Ctu2	cytosolic thiouridylase subunit 2	8	122476142	BB253397	66965	15	tRNA binding tRNA wobble uridine modification tRNA wobble position uridine thiolation cytoplasm cytosol tRNA processing sulfurtransferase activity protein-containing complex tRNA thio-modification	04122
1417840_at	Cep19	centrosomal protein 19	16	32099788	NM_025892	66994	18	spindle pole spindle pole molecular_function nucleoplasm cytoplasm centrosome centrosome centriole centriole cytoskeleton cilium cell projection organization microtubule anchoring at centrosome microtubule anchoring at centrosome ciliary basal body ciliary basal body cell projection cilium assembly vesicle targeting, trans-Golgi to periciliary membrane compartment vesicle targeting, trans-Golgi to periciliary membrane compartment
1437862_at	Rbm25	RNA binding motif protein 25	12	83635709, 83632242	AI159652	67039	31	regulation of alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome nucleic acid binding RNA binding mRNA binding mRNA binding nucleus cytoplasm mRNA processing apoptotic process RNA splicing nuclear speck regulation of apoptotic process	03040
1431694_a_at	Ctnnbip1	catenin beta interacting protein 1	4	149518240, 149545116	AK003595	67087	41	negative regulation of transcription by RNA polymerase II branching involved in ureteric bud morphogenesis regulation of vascular permeability involved in acute inflammatory response protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytosol cytosol beta-catenin binding beta-catenin binding beta-catenin binding anterior/posterior pattern specification Wnt signaling pathway negative regulation of Wnt signaling pathway negative regulation of Wnt signaling pathway negative regulation of Wnt signaling pathway beta-catenin destruction complex beta-catenin destruction complex negative regulation of protein-containing complex assembly negative regulation of protein binding negative regulation of DNA binding negative regulation of DNA-binding transcription factor activity negative regulation of DNA-binding transcription factor activity positive regulation of monocyte differentiation positive regulation of osteoblast differentiation negative regulation of smooth muscle cell proliferation negative regulation of transcription initiation by RNA polymerase II armadillo repeat domain binding negative regulation of mesenchymal cell proliferation negative regulation of canonical Wnt signaling pathway beta-catenin-ICAT complex	04310
1423569_at	Gatm	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	2	-122594472	AW108522	67092	43	kidney development mitochondrion mitochondrion mitochondrion mitochondrial inner membrane mitochondrial intermembrane space cytosol creatine metabolic process creatine biosynthetic process creatine biosynthetic process response to nutrient learning or memory response to organic substance muscle atrophy amidinotransferase activity amidinotransferase activity glycine amidinotransferase activity membrane transferase activity response to peptide hormone response to mercury ion positive regulation of cold-induced thermogenesis	00260 00330 01100
1417777_at	Ptgr1	prostaglandin reductase 1	4	-58965589	BC014865	67103	19	cytoplasm lipid metabolic process fatty acid metabolic process prostaglandin metabolic process prostaglandin metabolic process oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2-alkenal reductase [NAD(P)+] activity 2-alkenal reductase (NADP+) activity 13-prostaglandin reductase activity 15-oxoprostaglandin 13-oxidase activity 15-oxoprostaglandin 13-oxidase activity
1452067_at	Naaa	N-acylethanolamine acid amidase	5	-92257659	BI106821	67111	30	cytoplasm lysosome lysosome lipid metabolic process fatty acid metabolic process sphingosine metabolic process membrane lipid catabolic process hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds N-acylsphingosine amidohydrolase activity fatty acid amide hydrolase activity N-(long-chain-acyl)ethanolamine deacylase activity N-acylethanolamine metabolic process N-acylphosphatidylethanolamine metabolic process ceramidase activity DNA-binding transcription factor binding
1433688_x_at	Rpl14	ribosomal protein L14	9	120571516	BE993872	67115	44	cytoplasmic translation RNA binding RNA binding structural constituent of ribosome structural constituent of ribosome structural constituent of ribosome cytoplasm cytosol ribosome rRNA processing translation postsynaptic density cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic large ribosomal subunit cytosolic ribosome ribosomal large subunit biogenesis ribosomal large subunit biogenesis synapse synapse synapse presynapse postsynapse translation at presynapse translation at postsynapse ribonucleoprotein complex	03010
1437878_s_at	Ttc14	tetratricopeptide repeat domain 14	3	33800182	BB711506	67120	19	nucleic acid binding protein binding cellular_component biological_process
1438037_at	Herc6	hect domain and RLD 6	6	57580991	AW208668	67138	20	hematopoietic progenitor cell differentiation immune system process ubiquitin-protein transferase activity nucleoplasm cytoplasm cytoplasm cytosol ubiquitin-dependent protein catabolic process response to bacterium protein ubiquitination protein ubiquitination transferase activity cyclin binding innate immune response ubiquitin protein ligase activity ubiquitin protein ligase activity
1430526_a_at	Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	19	26605159, 26748402, 26748164	AK011935	67155	131	nucleotide binding chromatin chromatin transcription cis-regulatory region binding DNA binding DNA binding chromatin binding transcription coactivator activity helicase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm chromatin organization nucleosome assembly chromatin remodeling regulation of DNA-templated transcription regulation of transcription by RNA polymerase II nervous system development ATP-dependent activity, acting on DNA cell population proliferation positive regulation of cell population proliferation negative regulation of cell population proliferation negative regulation of cell population proliferation SWI/SNF complex SWI/SNF complex hydrolase activity regulation of mitotic metaphase/anaphase transition negative regulation of cell growth brahma complex aortic smooth muscle cell differentiation histone binding intracellular membrane-bounded organelle intermediate filament cytoskeleton positive regulation of T cell differentiation negative regulation of cell differentiation positive regulation of cell differentiation positive regulation of myoblast differentiation negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II fibroblast proliferation negative regulation of fibroblast proliferation hematopoietic stem cell homeostasis regulation of G0 to G1 transition SWI/SNF superfamily-type complex npBAF complex npBAF complex nBAF complex nBAF complex bBAF complex GBAF complex ATP-dependent chromatin remodeler activity positive regulation of stem cell population maintenance regulation of G1/S transition of mitotic cell cycle positive regulation of double-strand break repair regulation of nucleotide-excision repair
1417364_at	Eef1g	eukaryotic translation elongation factor 1 gamma	19	8967040	AF321126	67160	42	translation elongation factor activity nucleus cytoplasm cytoplasm endoplasmic reticulum translation translational elongation translational elongation
1453731_a_at	Dram2	DNA-damage regulated autophagy modulator 2	3	106547797	AK015888	67171	20	photoreceptor inner segment molecular_function cytoplasm lysosome lysosome Golgi apparatus plasma membrane autophagy apoptotic process visual perception regulation of autophagy regulation of autophagy membrane apical plasma membrane intracellular membrane-bounded organelle photoreceptor cell maintenance photoreceptor cell maintenance photoreceptor cell maintenance
1417062_at	Armc10	armadillo repeat containing 10	5	21646005	NM_026034	67211	23	p53 binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane endoplasmic reticulum membrane positive regulation of growth rate negative regulation of apoptotic process DNA binding domain binding negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
1448829_at	Smc6	structural maintenance of chromosomes 6	12	11265885, 11265885, 11265885	AV281575	67241	32	nucleotide binding DNA secondary structure binding telomere maintenance via recombination double-strand break repair via homologous recombination chromosome, centromeric region chromosome, telomeric region chromosome, telomeric region sex chromosome damaged DNA binding single-stranded DNA binding ATP binding nucleus nucleus nucleus nucleoplasm chromosome DNA repair double-strand break repair DNA recombination DNA damage response PML body PML body ATP hydrolysis activity Smc5-Smc6 complex Smc5-Smc6 complex Smc5-Smc6 complex ubiquitin protein ligase binding interchromatin granule site of double-strand break site of double-strand break negative regulation by host of viral genome replication positive regulation of chromosome segregation cellular senescence mitotic spindle pole
1417372_a_at	Peli1	pellino 1	11	21091323	BC016515	67245	81	protein polyubiquitination positive regulation of cytokine production ubiquitin-protein transferase activity protein binding nucleus regulation of Toll signaling pathway transferase activity positive regulation of B cell proliferation positive regulation of protein ubiquitination negative regulation of NF-kappaB transcription factor activity response to lipopolysaccharide response to lipopolysaccharide positive regulation of toll-like receptor 3 signaling pathway positive regulation of toll-like receptor 4 signaling pathway T cell proliferation T cell activation negative regulation of T cell proliferation positive regulation of canonical NF-kappaB signal transduction proteasome-mediated ubiquitin-dependent protein catabolic process response to dsRNA negative regulation of T cell activation positive regulation of B cell activation negative regulation of necroptotic process negative regulation of necroptotic process ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin protein ligase activity protein K63-linked ubiquitination protein K48-linked ubiquitination protein K48-linked ubiquitination protein K48-linked ubiquitination
1451965_at	LOC672450	V(kappa) gene product	6		AY058908	672450	1
1416766_at	Mtarc2	mitochondrial amidoxime reducing component 2	1	-184813065, -184813065	NM_133684	67247	29	catalytic activity mitochondrion mitochondrion mitochondrion mitochondrial outer membrane mitochondrial inner membrane peroxisome nitric oxide biosynthetic process nitrate reductase activity nitrate reductase activity membrane oxidoreductase activity oxidoreductase activity, acting on other nitrogenous compounds as donors molybdenum ion binding molybdenum ion binding pyridoxal phosphate binding nitrate metabolic process nitrate metabolic process molybdopterin cofactor binding molybdopterin cofactor binding cellular detoxification of nitrogen compound nitrite reductase activity
1455500_at	Rnf213	ring finger protein 213	11	119390098	AW556558	672511	46	nucleotide binding angiogenesis angiogenesis sprouting angiogenesis sprouting angiogenesis immune system process catalytic activity ubiquitin-protein transferase activity ubiquitin-protein transferase activity ATP binding nucleolus nucleolus cytoplasm lipid droplet cytosol cytosol ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process lipid metabolic process metabolic process protein ubiquitination transferase activity hydrolase activity ATP hydrolysis activity regulation of lipid metabolic process defense response to bacterium defense response to bacterium metal ion binding protein autoubiquitination ubiquitin protein ligase activity protein K63-linked ubiquitination xenophagy lipid ubiquitination lipid ubiquitination lipid droplet formation negative regulation of non-canonical Wnt signaling pathway negative regulation of non-canonical Wnt signaling pathway
1417780_at	Cers4	ceramide synthase 4	8	4493404	BB006809	67260	34	DNA binding endoplasmic reticulum lipid metabolic process membrane transferase activity sphingolipid biosynthetic process ceramide biosynthetic process ceramide biosynthetic process ceramide biosynthetic process sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity sphingosine N-acyltransferase activity
1429503_at	Dipk1a	divergent protein kinase domain 1A	5	-107908041	AK013580	67266	21	molecular_function cellular_component endoplasmic reticulum biological_process membrane
1418007_at	Paxbp1	PAX3 and PAX7 binding protein 1	16	-91014036	BM932567	67367	27	mRNA splicing, via spliceosome DNA binding nucleus nucleus transcription by RNA polymerase II muscle organ development transcription factor binding regulation of skeletal muscle satellite cell proliferation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II histone methyltransferase binding positive regulation of myoblast proliferation
1448960_at	Cxxc5	CXXC finger 5	18	35830313, 35829787, 35854686	NM_133687	67393	42	negative regulation of transcription by RNA polymerase II DNA binding nucleus nucleus nucleoplasm cytoplasm cytosol zinc ion binding methyl-CpG binding methyl-CpG binding regulation of generation of precursor metabolites and energy sequence-specific DNA binding metal ion binding DNA-binding transcription factor binding
1456739_x_at	Armcx2	armadillo repeat containing, X-linked 2	X	-134804141	BB392869	67416	19	molecular_function mitochondrion mitochondrion mitochondrial outer membrane biological_process membrane
1417066_at	Coq8a	coenzyme Q8A	1	-180165237, -180165237, -180166613	AK014605	67426	24	nucleotide binding ATP binding mitochondrion mitochondrion ubiquinone biosynthetic process ubiquinone biosynthetic process membrane kinase activity phosphorylation transferase activity ADP binding
1429642_at	Zfand4	zinc finger, AN1-type domain 4	6	116264218, 116266531	AK012639	67492	13	molecular_function cellular_component biological_process zinc ion binding metal ion binding
1428821_at	Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2	2	-26593056	AK010891	67512	35	positive regulation of cytokine production 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerol-3-phosphate O-acyltransferase activity 1-acylglycerol-3-phosphate O-acyltransferase activity endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane lipid metabolic process phosphatidic acid biosynthetic process phosphatidic acid biosynthetic process phospholipid biosynthetic process membrane transferase activity acyltransferase activity triglyceride biosynthetic process triglyceride biosynthetic process	00561 00564 01100 04975
1436419_a_at	1700097N02Rik	RIKEN cDNA 1700097N02 gene	17	-30622440	AA266367	67522	11	molecular_function cellular_component biological_process
1435351_at	Bend5	BEN domain containing 5	4	111415005	AA189197	67621	12	molecular_function DNA binding Golgi apparatus negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription
1456446_at	4930523C07Rik	RIKEN cDNA 4930523C07 gene	1	160044379, 160044379	BM246687	67647	9	molecular_function cellular_component biological_process
1424802_a_at	Luc7l3	LUC7-like 3 (S. cerevisiae)	11	-94291072	AW536179	67684	25	DNA binding mRNA binding mRNA binding nucleus nucleoplasm U1 snRNP U1 snRNP mRNA splice site recognition mRNA splice site recognition mRNA processing RNA splicing nuclear speck U2-type prespliceosome
1453939_x_at	Gm9706	predicted gene 9706	17		AK019325	677168	7
1448747_at	Fbxo32	F-box protein 32	15	-58175878	AF441120	67731	102	protein binding nucleus nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol cytosol negative regulation of cardiac muscle hypertrophy positive regulation of cardiac muscle cell apoptotic process response to electrical stimulus involved in regulation of muscle adaptation muscle atrophy response to denervation involved in regulation of muscle adaptation protein ubiquitination protein ubiquitination SCF ubiquitin ligase complex SCF ubiquitin ligase complex Z disc cellular response to dexamethasone stimulus
1421457_a_at	Samsn1	SAM domain, SH3 domain and nuclear localization signals, 1	16	-75858793	NM_023380	67742	24	phosphotyrosine residue binding phosphotyrosine residue binding negative regulation of adaptive immune response nucleus nucleus nucleus cytoplasm cytoplasm cytosol cell projection negative regulation of peptidyl-tyrosine phosphorylation negative regulation of peptidyl-tyrosine phosphorylation negative regulation of B cell activation negative regulation of B cell activation
1437297_at	Chd8	chromodomain helicase DNA binding protein 8	14	-52198150	BB409788	67772	84	negative regulation of transcription by RNA polymerase II nucleotide binding chromatin in utero embryonic development startle response p53 binding DNA binding DNA binding DNA binding chromatin binding chromatin binding chromatin binding helicase activity protein binding ATP binding nucleus nucleus nucleus nucleoplasm chromatin organization chromatin remodeling chromatin remodeling mRNA processing brain development brain development brain development beta-catenin binding Wnt signaling pathway hydrolase activity ATP hydrolysis activity negative regulation of Wnt signaling pathway protein-containing complex methylated histone binding social behavior histone binding histone binding histone binding negative regulation of apoptotic process negative regulation of apoptotic process negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase III digestive tract development digestive tract development digestive tract development prepulse inhibition armadillo repeat domain binding MLL1 complex MLL1 complex negative regulation of canonical Wnt signaling pathway negative regulation of canonical Wnt signaling pathway ATP-dependent chromatin remodeler activity ATP-dependent chromatin remodeler activity negative regulation of fibroblast apoptotic process	04310
1418580_at	Rtp4	receptor transporter protein 4	16	23609918	BC024872	67775	18	detection of chemical stimulus involved in sensory perception of bitter taste detection of chemical stimulus involved in sensory perception of bitter taste protein binding cytoplasm cytoplasm protein targeting to membrane protein targeting to membrane membrane olfactory receptor binding metal ion binding protein insertion into membrane defense response to virus
1426221_at	Vwa5a	von Willebrand factor A domain containing 5A	9	38718267	BC004727	67776	21	molecular_function extracellular matrix structural constituent nucleoplasm biological_process collagen-containing extracellular matrix
1422678_at	Dgat2	diacylglycerol O-acyltransferase 2	7	-99153662	AK002443	67800	73	2-acylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity diacylglycerol O-acyltransferase activity cytoplasm mitochondrion endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum membrane endoplasmic reticulum membrane endoplasmic reticulum membrane lipid droplet lipid droplet cytosol glycerol metabolic process lipid metabolic process monoacylglycerol biosynthetic process diacylglycerol biosynthetic process O-acyltransferase activity positive regulation of triglyceride biosynthetic process membrane membrane transferase activity acyltransferase activity triglyceride biosynthetic process triglyceride biosynthetic process triglyceride biosynthetic process triglyceride biosynthetic process lipid storage lipid storage low-density lipoprotein particle clearance long-chain fatty-acyl-CoA metabolic process long-chain fatty-acyl-CoA metabolic process intracellular triglyceride homeostasis cholesterol homeostasis protein homodimerization activity intracellular membrane-bounded organelle positive regulation of gluconeogenesis negative regulation of fatty acid oxidation diacylglycerol metabolic process diacylglycerol metabolic process diacylglycerol metabolic process perinuclear region of cytoplasm retinol O-fatty-acyltransferase activity regulation of lipoprotein metabolic process fatty acid homeostasis fat pad development cellular response to oleic acid regulation of cholesterol metabolic process regulation of plasma lipoprotein particle levels perinuclear endoplasmic reticulum membrane	00561 01100 04975
1456377_x_at	Limd2	LIM domain containing 2	11	-106156253, -106156253, -106156253	AV010467	67803	23	molecular_function nucleus nucleoplasm cytoplasm cytosol plasma membrane biological_process actin cytoskeleton metal ion binding actin filament binding actin filament bundle assembly
1460224_at	Snx2	sorting nexin 2	18	53176291	BC006960	67804	31	epidermal growth factor receptor binding insulin receptor binding cytoplasm lysosome endosome endosome intracellular protein transport lipid binding endosome membrane endosome membrane protein transport membrane membrane retromer complex retromer, tubulation complex protein-containing complex early endosome to Golgi transport phosphatidylinositol binding phosphatidylinositol binding retrograde transport, endosome to Golgi identical protein binding protein homodimerization activity cell projection protein heterodimerization activity lamellipodium morphogenesis transferrin receptor binding leptin receptor binding
1416527_at	Rab32	RAB32, member RAS oncogene family	10	-10545038	NM_026405	67844	41	nucleotide binding GTPase activity GTPase activity protein binding GTP binding mitochondrion mitochondrion mitochondrion mitochondrial outer membrane early endosome endoplasmic reticulum Golgi apparatus trans-Golgi network trans-Golgi network intracellular protein transport mitochondrion organization endomembrane system membrane vesicle-mediated transport antigen processing and presentation GTP-dependent protein binding cytoplasmic vesicle vesicle melanosome organization melanosome membrane endosome to melanosome transport AP-1 adaptor complex binding AP-3 adaptor complex binding BLOC-2 complex binding melanosome melanosome melanosome mitochondria-associated endoplasmic reticulum membrane phagocytic vesicle protein localization to membrane phagosome maturation melanosome assembly
1452732_at	Asprv1	aspartic peptidase, retroviral-like 1	6	86628173	AK004007	67855	19	aspartic-type endopeptidase activity aspartic-type endopeptidase activity proteolysis peptidase activity membrane protein processing protein processing hydrolase activity skin development
1425684_at	Akr1b10	aldo-keto reductase family 1, member B10	6	34384246	BB493454	67861	16	retinal dehydrogenase activity alditol:NADP+ 1-oxidoreductase activity estradiol 17-beta-dehydrogenase [NAD(P)] activity extracellular region mitochondrion mitochondrion mitochondrion lysosome cytosol cytosol alcohol dehydrogenase (NADP+) activity oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor geranylgeranyl reductase activity indanol dehydrogenase activity NADP-retinol dehydrogenase activity
1424039_at	Saraf	store-operated calcium entry-associated regulatory factor	8	34154578	BC022616	67887	22	endoplasmic reticulum endoplasmic reticulum membrane monoatomic ion transport calcium ion transport membrane endoplasmic reticulum-plasma membrane contact site regulation of store-operated calcium entry regulation of store-operated calcium entry
1416939_at	Ppa1	pyrophosphatase (inorganic) 1	10	61648620	NM_026438	67895	37	magnesium ion binding inorganic diphosphate phosphatase activity inorganic diphosphate phosphatase activity cytoplasm phosphate-containing compound metabolic process phosphate-containing compound metabolic process pyrophosphatase activity hydrolase activity metal ion binding	00190
1433530_at	Rpl41	ribosomal protein L41	10	-128548109	BI694945	67945	26	cytoplasmic translation structural constituent of ribosome cytoplasm cytosol ribosome translation cytosolic large ribosomal subunit cytosolic large ribosomal subunit ribonucleoprotein complex	03010
1416431_at	Tubb6	tubulin, beta 6 class V	18	67390730	NM_026473	67951	43	nucleotide binding microtubule cytoskeleton organization mitotic cell cycle GTPase activity structural constituent of cytoskeleton structural constituent of cytoskeleton GTP binding GTP binding cytoplasm cytoplasm cytoskeleton microtubule microtubule microtubule-based process microtubule cytoskeleton intercellular bridge metal ion binding mitotic spindle	04145 04540
1416713_at	Tppp3	tubulin polymerization-promoting protein family member 3	8	-105467491	NM_026481	67971	32	microtubule bundle formation microtubule bundle formation cytoplasm cytoskeleton microtubule microtubule embryo implantation tubulin binding tubulin binding positive regulation of protein polymerization decidualization microtubule polymerization microtubule polymerization perinuclear region of cytoplasm microtubule bundle
1417153_at	Nacc2	nucleus accumbens associated 2, BEN and BTB (POZ) domain containing	2	-26055535, -26055535	NM_026495	67991	24	negative regulation of transcription by RNA polymerase II chromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding nucleus nucleolus mitochondrion negative regulation of cell population proliferation protein-containing complex localization protein homodimerization activity histone deacetylase binding protein-containing complex binding negative regulation of DNA-templated transcription protein homooligomerization positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
1417126_a_at	Rpl22l1	ribosomal protein L22 like 1	3	28805507	NM_026517	68028	25	cytoplasmic translation RNA binding structural constituent of ribosome structural constituent of ribosome cytosol ribosome translation ribonucleoprotein complex	03010
1449415_at	Chd1l	chromodomain helicase DNA binding protein 1-like	3	-97560747	NM_026539	68058	28	nucleotide binding nucleotide binding DNA helicase activity ATP binding nucleus nucleus nucleoplasm chromosome cytosol plasma membrane DNA repair chromatin remodeling chromatin remodeling DNA damage response DNA damage response hydrolase activity ATP hydrolysis activity nucleosome binding site of double-strand break site of DNA damage histone reader activity ATP-dependent chromatin remodeler activity poly-ADP-D-ribose modification-dependent protein binding
1423803_s_at	Nop53	NOP53 ribosome biogenesis factor	7	-15937835	BC017637	68077	23	ribosomal large subunit assembly ribosomal large subunit assembly negative regulation of transcription by RNA polymerase II fibrillar center regulation of protein phosphorylation p53 binding protein binding nucleus nucleoplasm nucleolus nucleolus nucleolus cytosol DNA repair rRNA processing DNA damage response mitotic G2 DNA damage checkpoint signaling 5S rRNA binding 5S rRNA binding negative regulation of protein-containing complex assembly negative regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process positive regulation of proteasomal ubiquitin-dependent protein catabolic process rDNA heterochromatin regulation of RIG-I signaling pathway ribosome biogenesis identical protein binding regulation of apoptotic process intracellular membrane-bounded organelle protein stabilization regulation of cell cycle negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction cellular response to hypoxia regulation of signal transduction by p53 class mediator negative regulation of signal transduction by p53 class mediator negative regulation of transcription of nucleolar large rRNA by RNA polymerase I protein localization to nucleolus positive regulation of protein K63-linked deubiquitination regulation of aerobic respiration protein localization to nucleoplasm
1416536_at	Pwwp3a	PWWP domain containing 3A, DNA repair factor	10	80226597	NM_023431	68114	17	nucleus nucleus nucleoplasm cytosol cytosol DNA repair DNA repair chromatin organization chromatin organization DNA damage response nucleosome binding nucleosome binding
1455203_at	A930003A15Rik	RIKEN cDNA A930003A15 gene	16	-19876567	BB522820	68162	10	molecular_function cellular_component biological_process
1434581_at	Mturn	maturin, neural progenitor differentiation regulator homolog (Xenopus)	6	54681623	BB167663	68235	19	molecular_function cytoplasm cytoplasm multicellular organism development regulation of signaling negative regulation of NF-kappaB transcription factor activity positive regulation of megakaryocyte differentiation positive regulation of megakaryocyte differentiation positive regulation of megakaryocyte differentiation positive regulation of JNK cascade neuron development positive regulation of ERK1 and ERK2 cascade
1437309_a_at	Rpa1	replication protein A1	11	-75300258	BB491281	68275	81	telomere maintenance double-strand break repair via homologous recombination double-strand break repair via homologous recombination double-strand break repair via homologous recombination condensed chromosome condensed nuclear chromosome lateral element male germ cell nucleus in utero embryonic development nucleic acid binding DNA binding chromatin binding damaged DNA binding damaged DNA binding single-stranded DNA binding nucleus nucleus nucleoplasm nucleoplasm DNA replication factor A complex DNA replication factor A complex DNA replication DNA repair base-excision repair nucleotide-excision repair nucleotide-excision repair mismatch repair DNA recombination DNA damage response telomere maintenance via telomerase positive regulation of cell population proliferation PML body hemopoiesis protein localization to chromosome site of double-strand break single-stranded telomeric DNA binding metal ion binding homeostasis of number of cells within a tissue chromosome organization meiotic cell cycle meiotic cell cycle site of DNA damage G-rich strand telomeric DNA binding chromatin-protein adaptor activity protein localization to site of double-strand break	03030 03420 03430 03440
1431705_a_at	Mcoln2	mucolipin 2	3	146150173, 146149832	AK014467	68279	23	adaptive immune response immune system process monoatomic cation channel activity calcium channel activity lysosome endosome plasma membrane monoatomic ion transport calcium ion transport protein transport membrane membrane positive regulation of chemokine production monoatomic ion transmembrane transport identical protein binding innate immune response recycling endosome calcium ion transmembrane transport positive regulation of monocyte chemotactic protein-1 production positive regulation of macrophage inflammatory protein 1 alpha production positive regulation of chemokine (C-C motif) ligand 5 production NAADP-sensitive calcium-release channel activity macrophage migration neutrophil migration regulation of chemokine (C-X-C motif) ligand 2 production positive regulation of chemokine (C-X-C motif) ligand 2 production
1454893_at	Entrep3	endosomal transmembrane epsin interactor 3	3	89183142	BB765852	68521	12	molecular_function cellular_component biological_process membrane WW domain binding
1452353_at	Gpr155	G protein-coupled receptor 155	2	-73341505	BB762731	68526	14	molecular_function lysosome lysosomal membrane lipid binding cholesterol binding membrane negative regulation of BMP signaling pathway cellular response to amino acid starvation intracellular signal transduction cognition transmembrane transport cellular response to cholesterol positive regulation of TORC1 signaling
1435464_at	Smim14	small integral membrane protein 14	5	-65446843, -65446843, -65446843, -65446843, -65446843, -65446843	BB701294	68552	21	blastocyst hatching molecular_function endoplasmic reticulum endoplasmic reticulum membrane
1429072_at	Col6a4	collagen, type VI, alpha 4	9	-105990317	AK003211	68553	24	collagen binding extracellular region collagen trimer cell adhesion extracellular matrix structural constituent conferring tensile strength extracellular matrix organization extracellular matrix protein-containing complex collagen-containing extracellular matrix	04510 04512 04974
1428583_at	Nufip2	nuclear FMR1 interacting protein 2	11	77686138	BQ176203	68564	32	RNA binding RNA binding nucleus nucleoplasm nucleoplasm cytoplasm cytosol ribosome cytoplasmic stress granule cytoplasmic stress granule nuclear body
1429352_at	Mocos	molybdenum cofactor sulfurase	18	24653690	AK003797	68591	16	catalytic activity cellular_component Mo-molybdopterin cofactor biosynthetic process Mo-molybdopterin cofactor sulfurase activity Mo-molybdopterin cofactor sulfurase activity transferase activity molybdenum ion binding pyridoxal phosphate binding molybdopterin cofactor biosynthetic process molybdopterin cofactor metabolic process molybdopterin cofactor metabolic process molybdenum cofactor sulfurtransferase activity
1424254_at	Ifitm1	interferon induced transmembrane protein 1	7	140967428, 140968075, 140968027	BC027285	68713	37	ossification somitogenesis immune system process molecular_function lysosome lysosomal membrane early endosome plasma membrane plasma membrane negative regulation of cell population proliferation response to virus response to virus anterior/posterior pattern specification membrane negative regulation of cell migration protein-containing complex response to type II interferon response to type II interferon response to interferon-alpha response to interferon-alpha response to interferon-beta response to interferon-beta negative regulation of viral genome replication negative regulation of viral genome replication innate immune response positive regulation of osteoblast differentiation negative regulation of viral entry into host cell negative regulation of viral entry into host cell negative regulation of viral entry into host cell defense response to virus defense response to virus type I interferon-mediated signaling pathway	04662
1452646_at	Trp53inp2	transformation related protein 53 inducible nuclear protein 2	2	155381855	AK003956	68728	22	autophagosome assembly autophagosome assembly osteoblast differentiation tissue homeostasis nucleus nucleus cytoplasm autophagosome autophagosome cytosol ubiquitin-dependent protein catabolic process autophagy protein localization macroautophagy cytoplasmic vesicle ubiquitin binding positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription negative regulation of protein localization
1416617_at	Acss1	acyl-CoA synthetase short-chain family member 1	2	-150618110	NM_080575	68738	37	nucleotide binding acetate-CoA ligase activity acetate-CoA ligase activity acetate-CoA ligase activity ATP binding mitochondrion mitochondrion mitochondrial matrix mitochondrial matrix acetyl-CoA biosynthetic process acetyl-CoA biosynthetic process acetyl-CoA biosynthetic process lipid metabolic process AMP binding ligase activity acetate biosynthetic process acetyl-CoA biosynthetic process from acetate propionate biosynthetic process propionate-CoA ligase activity	00010 00620 00640 01100
1419599_s_at	Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	19	-11586605	NM_026835	68774	19	molecular_function trans-Golgi network trans-Golgi network plasma membrane cell surface receptor signaling pathway membrane
1454857_at	Rnf122	ring finger protein 122	8	31111826, 31115052	AW551457	68867	19	cytoplasm endoplasmic reticulum Golgi apparatus negative regulation of mitochondrial membrane potential membrane positive regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process metal ion binding protein autoubiquitination ubiquitin protein ligase activity
1424509_at	Cd177	CD177 antigen	7	-24743982	BC027283	68891	21	protease binding immune system process integrin binding plasma membrane cell adhesion leukocyte cell-cell adhesion leukocyte cell-cell adhesion membrane regulation of endocytosis secretory granule membrane positive regulation of superoxide anion generation protein localization to cell surface positive regulation of neutrophil degranulation positive regulation of neutrophil degranulation plasma membrane raft plasma membrane raft innate immune response cell-cell junction maintenance cell-cell junction maintenance calcium-dependent protein binding tertiary granule membrane neutrophil extravasation cell-cell adhesion via plasma-membrane adhesion molecules cell-cell adhesion via plasma-membrane adhesion molecules regulation of integrin-mediated signaling pathway regulation of integrin-mediated signaling pathway
1424337_at	Snx15	sorting nexin 15	19	-6119398	BC016091	69024	19	nucleolus cytoplasm cytosol plasma membrane lipid binding protein transport membrane cytoplasmic vesicle phosphatidylinositol binding intracellular membrane-bounded organelle
1422497_at	Slc30a5	solute carrier family 30 (zinc transporter), member 5	13	-100802647	NM_022885	69048	28	Golgi membrane zinc ion transmembrane transporter activity zinc ion transmembrane transporter activity nucleoplasm nucleolus endoplasmic reticulum membrane Golgi apparatus Golgi apparatus plasma membrane GPI anchor biosynthetic process monoatomic ion transport monoatomic cation transport zinc ion transport intracellular zinc ion homeostasis intracellular zinc ion homeostasis monoatomic cation transmembrane transporter activity response to zinc ion ER to Golgi transport vesicle membrane antiporter activity membrane apical plasma membrane zinc efflux transmembrane transporter activity insulin processing secretory granule secretory granule membrane cytoplasmic vesicle cytoplasmic vesicle trans-Golgi network membrane metal ion binding transmembrane transport zinc ion import into organelle zinc ion import across plasma membrane zinc:proton antiporter activity zinc ion import into Golgi lumen zinc ion import into Golgi lumen Golgi cis cisterna membrane
1434493_at	Rbis	ribosomal biogenesis factor	3	-14606288, -14606288	BG092222	69126	15	molecular_function nucleus nucleoplasm nucleolus nucleolus cytosol ribosome biogenesis ribosome biogenesis
1429889_at	Fcmr	Fc fragment of IgM receptor	1	130865776	AK007714	69169	34	polymeric immunoglobulin binding IgM binding high-affinity IgM receptor activity immune system process immunoglobulin transcytosis in epithelial cells humoral immune response mediated by circulating immunoglobulin transmembrane signaling receptor activity protein binding lysosomal membrane plasma membrane plasma membrane plasma membrane external side of plasma membrane cell surface membrane early endosome membrane trans-Golgi network membrane trans-Golgi network membrane regulation of B cell receptor signaling pathway negative regulation of lymphocyte apoptotic process Fc receptor-mediated immune complex endocytosis inhibition of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of extrinsic apoptotic signaling pathway
1428637_at	Dyrk2	dual-specificity tyrosine phosphorylation regulated kinase 2	10	-118859348	AK007736	69181	27	ubiquitin ligase complex nucleotide binding magnesium ion binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity ATP binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytosol cytoskeleton protein phosphorylation apoptotic process smoothened signaling pathway kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation peptidyl-threonine phosphorylation peptidyl-tyrosine phosphorylation manganese ion binding intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator positive regulation of glycogen biosynthetic process negative regulation of calcineurin-NFAT signaling cascade ribonucleoprotein complex
1430612_at	Mcemp1	mast cell expressed membrane protein 1	8	3665761	BB533148	69189	13	molecular_function cellular_component biological_process membrane identical protein binding
1427837_at	Igkv15-103	immunoglobulin kappa chain variable 15-103	6		U25103	692169	10	immunoglobulin production extracellular space immune response IgG immunoglobulin complex
1427757_at	Igk-V21	immunoglobulin kappa chain variable 21 (V21)	6		D29670	692179	22
1423142_a_at	Gtpbp4	GTP binding protein 4	13	-8972477	AI987834	69237	34	regulation of cyclin-dependent protein serine/threonine kinase activity nucleotide binding maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) RNA binding GTPase activity GTPase activity GTP binding nucleus nucleoplasm nucleolus nucleolus cytoplasm cytosol negative regulation of DNA replication negative regulation of cell population proliferation negative regulation of cell-cell adhesion negative regulation of cell migration negative regulation of protein ubiquitination nuclear membrane negative regulation of collagen binding ribosome biogenesis ribosomal large subunit biogenesis ribosomal large subunit biogenesis perinuclear region of cytoplasm protein stabilization preribosome binding	03008
1435664_at	Zfp397	zinc finger protein 397	18	23954687	AV342828	69256	17	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus nucleolus cytoplasm cytosol plasma membrane regulation of transcription by RNA polymerase II microtubule cytoskeleton protein homodimerization activity negative regulation of DNA-templated transcription protein heterodimerization activity
1452798_s_at	Mapk1ip1	mitogen-activated protein kinase 1 interacting protein 1	7	-138835817	AK009250	69546	19	cellular_component cytoplasm cytoskeleton multicellular organism development biological_process identical protein binding meiotic cell cycle
1424921_at	Bst2	bone marrow stromal cell antigen 2	8	-71534255	BC008532	69550	50	immune system process negative regulation of plasmacytoid dendritic cell cytokine production cytoplasm endosome multivesicular body Golgi apparatus Golgi apparatus plasma membrane metalloendopeptidase inhibitor activity metalloendopeptidase inhibitor activity response to virus response to virus cell surface cell surface cell surface membrane apical plasma membrane negative regulation of cell growth negative regulation of cell migration regulation of actin cytoskeleton organization response to type II interferon response to interferon-alpha response to interferon-beta identical protein binding protein homodimerization activity intracellular membrane-bounded organelle negative regulation of viral genome replication negative regulation of viral genome replication innate immune response innate immune response innate immune response defense response to virus defense response to virus side of membrane negative regulation of intracellular transport of viral material negative regulation of intracellular transport of viral material negative regulation of intracellular transport of viral material
1435020_at	Klhdc2	kelch domain containing 2	12	69296680	BE980167	69554	23	protein binding nucleus nucleoplasm nuclear body Cul2-RING ubiquitin ligase complex nuclear membrane proteasome-mediated ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process via the C-end degron rule pathway ubiquitin ligase-substrate adaptor activity
1449027_at	Rhou	ras homolog family member U	8	123653928	AF378088	69581	25	G1/S transition of mitotic cell cycle nucleotide binding GTPase activity GTPase activity GTP binding GTP binding Golgi apparatus plasma membrane plasma membrane endocytosis cytoskeleton organization actin filament organization establishment or maintenance of cell polarity small GTPase-mediated signal transduction regulation of cell shape regulation of cell shape membrane Rac protein signal transduction protein kinase binding actin cytoskeleton organization Cdc42 protein signal transduction cell projection metal ion binding anchoring junction
1452839_at	Dph5	diphthamide biosynthesis 5	3	115888182	AK010475	69740	17	cellular_component methyltransferase activity transferase activity protein histidyl modification to diphthamide methylation
1439956_at	Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	19	11518558	BE692425	69774	15	molecular_function trans-Golgi network trans-Golgi network plasma membrane cell surface receptor signaling pathway membrane
1428947_at	Mzb1	marginal zone B and B1 cell-specific protein 1	18	-35647264	AK008016	69816	22	positive regulation of immunoglobulin production protein binding extracellular region extracellular region extracellular region cytoplasm endoplasmic reticulum endoplasmic reticulum lumen positive regulation of cell population proliferation positive regulation of cell population proliferation regulation of B cell proliferation regulation of B cell proliferation integrin activation endoplasmic reticulum chaperone complex endoplasmic reticulum chaperone complex regulation of cell population proliferation regulation of insulin receptor signaling pathway
1453047_at	Tspo2	translocator protein 2	17	-48448434	AK011003	70026	12	endoplasmic reticulum endoplasmic reticulum plasma membrane cholesterol binding cholesterol binding membrane organelle membrane intracellular cholesterol transport lipid droplet organization enucleate erythrocyte differentiation import across plasma membrane 5-aminolevulinic acid import across plasma membrane 5-aminolevulinic acid transmembrane transporter activity
1452197_at	Smc4	structural maintenance of chromosomes 4	3	69004737	AV172948	70099	40	single strand break repair nucleotide binding chromosome, centromeric region condensed nuclear chromosome condensin complex condensin complex condensin complex condensin complex chromatin binding single-stranded DNA binding protein binding ATP binding nucleus chromosome cytoplasm cytosol cell cycle mitotic chromosome condensation meiotic chromosome condensation nuclear speck ATP hydrolysis activity chromosome condensation meiotic chromosome segregation chromosome organization cell division kinetochore organization positive regulation of chromosome segregation positive regulation of chromosome separation positive regulation of chromosome condensation
1430878_at	2210406H18Rik	RIKEN cDNA 2210406H18 gene	7		AV078837	70133	7	molecular_function cellular_component biological_process
1428512_at	Bhlhb9	basic helix-loop-helix domain containing, class B9	X	135885850	AK012577	70237	25	nucleus nucleus cytoplasm cytosol learning or memory protein homodimerization activity negative regulation of neuron apoptotic process positive regulation of neurogenesis positive regulation of synapse assembly positive regulation of dendritic spine morphogenesis
1440795_x_at	Rabep2	rabaptin, RAB GTPase binding effector protein 2	7	126428766	BB259371	70314	25	GTPase activator activity cytoplasm endosome centrosome cytosol cytoskeleton endocytosis growth factor activity protein transport cell projection organization ciliary basal body cell projection intracellular membrane-bounded organelle intracellular membrane-bounded organelle regulation of cilium assembly
1428572_at	Basp1	brain abundant, membrane attached signal protein 1	15	-25363276	AK011545	70350	45	chromatin transcription cis-regulatory region binding transcription cis-regulatory region binding transcription corepressor activity transcription corepressor activity transcription corepressor activity protein binding nucleus nucleus nucleus cytoplasm cytoplasm cytoplasm plasma membrane COP9 signalosome membrane nuclear matrix PML body nuclear speck protein domain specific binding cell junction cell projection negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription podocyte differentiation
1423989_at	Tecpr1	tectonin beta-propeller repeat containing 1	5	-144194441	BC025567	70381	22	autophagosome membrane autophagosome membrane nucleoplasm lysosome lysosomal membrane lysosomal membrane autophagy lipid binding membrane macroautophagy cytoplasmic vesicle phosphatidylinositol-3-phosphate binding phosphatidylinositol-3-phosphate binding protein-containing complex intracellular membrane-bounded organelle autophagosome maturation autophagosome maturation regulation of autophagosome maturation
1419033_at	Stk26	serine/threonine kinase 26	X	50841370	AW556821	70415	26	Golgi membrane nucleotide binding magnesium ion binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding cytoplasm cytoplasm Golgi apparatus Golgi apparatus Golgi-associated vesicle cytosol protein phosphorylation protein phosphorylation apoptotic process cellular response to starvation membrane kinase activity phosphorylation apical plasma membrane transferase activity microvillus assembly negative regulation of cell migration negative regulation of cell migration stress-activated protein kinase signaling cascade response to hydrogen peroxide identical protein binding protein homodimerization activity regulation of apoptotic process protein autophosphorylation metal ion binding perinuclear region of cytoplasm cell periphery
1429461_at	Ints2	integrator complex subunit 2	11	-86210680	AK013101	70422	24	molecular_function nucleus cytoplasm membrane snRNA processing integrator complex integrator complex snRNA 3'-end processing
1429383_at	Csnk1g3	casein kinase 1, gamma 3	18	53862112	BM195380	70425	24	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus cytoplasm cytoplasm plasma membrane protein phosphorylation endocytosis signal transduction Wnt signaling pathway kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation positive regulation of canonical Wnt signaling pathway	04340
1426623_a_at	Arhgap17	Rho GTPase activating protein 17	7	-123279148	AV351061	70497	36	GTPase activator activity GTPase activator activity intracellular anatomical structure cytoplasm cytosol cytosol plasma membrane plasma membrane bicellular tight junction actin filament organization signal transduction membrane SH3 domain binding calcium-ion regulated exocytosis regulation of actin cytoskeleton organization regulation of Rac protein signal transduction positive regulation of GTPase activity anchoring junction
1427050_at	Txndc16	thioredoxin domain containing 16	14	-45134447	BC027108	70561	15	molecular_function extracellular region endoplasmic reticulum endoplasmic reticulum lumen biological_process
1447774_x_at	Prxl2a	peroxiredoxin like 2A	14	-40993734, -40993734, -40993734, -40993734, -40993734	AV332575	70564	26	extracellular region cytoplasm cytoplasm mitochondrion antioxidant activity antioxidant activity regulation of osteoclast differentiation
1429413_at	Cpm	carboxypeptidase M	10	117629499	AK017670	70574	25	carboxypeptidase activity metallocarboxypeptidase activity metallocarboxypeptidase activity extracellular space plasma membrane proteolysis peptide metabolic process peptidase activity metallopeptidase activity zinc ion binding membrane protein processing hydrolase activity metal ion binding side of membrane
1447100_s_at	Fam241a	family with sequence similarity 241, member A	3	-127869687	C80506	70617	15	molecular_function Golgi apparatus biological_process membrane intracellular membrane-bounded organelle
1418401_a_at	Dusp16	dual specificity phosphatase 16	6	-134715467	NM_130447	70686	40	phosphoprotein phosphatase activity nucleus nucleus nucleoplasm cytoplasm cytoplasm protein dephosphorylation protein tyrosine/threonine phosphatase activity JUN kinase binding dephosphorylation phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity MAP kinase tyrosine phosphatase activity peptidyl-tyrosine dephosphorylation negative regulation of MAPK cascade negative regulation of MAPK cascade negative regulation of JUN kinase activity MAPK export from nucleus mitogen-activated protein kinase p38 binding mitogen-activated protein kinase binding	04010
1430570_at	Kynu	kynureninase	2	43555324, 43555324, 43555324	AV227891	70789	16	nucleoplasm cytoplasm cytoplasm mitochondrion mitochondrion cytosol tryptophan catabolic process NAD biosynthetic process hydrolase activity pyridine nucleotide biosynthetic process tryptophan catabolic process to kynurenine tryptophan catabolic process to acetyl-CoA quinolinate biosynthetic process pyridoxal phosphate binding kynureninase activity kynureninase activity response to type II interferon response to vitamin B6 protein homodimerization activity anthranilate metabolic process anthranilate metabolic process 3-hydroxykynureninase activity	00380 01100
1428727_at	Cep192	centrosomal protein 192	18	67800106	AK014527	70799	25	pericentriolar material pericentriolar material cytoplasm cytoplasm centrosome centrosome centriole centriole microtubule nucleation mitotic spindle assembly checkpoint signaling centriole replication centriole replication response to bacterium protein kinase binding phosphatase binding regulation of centriole replication regulation of centrosome cycle regulation of establishment of protein localization protein localization to centrosome centrosome-templated microtubule nucleation centrosome-templated microtubule nucleation mitotic spindle assembly mitotic spindle assembly procentriole procentriole replication complex
1433648_at	Spag9	sperm associated antigen 9	11	94044129, 93996090	BM938614	70834	69	negative regulation of protein phosphorylation MAP-kinase scaffold activity MAP-kinase scaffold activity protein binding cytoplasm cytoplasm lysosome lysosomal membrane cytosol cytosol JUN kinase binding JUN kinase binding membrane vesicle-mediated transport kinesin binding kinesin binding signaling receptor complex adaptor activity positive regulation of cell migration lysosome localization centriolar satellite retrograde transport, endosome to Golgi identical protein binding positive regulation of MAPK cascade positive regulation of MAPK cascade negative regulation of neuron differentiation positive regulation of neuron differentiation striated muscle cell differentiation negative regulation of dendrite extension
1452974_at	Nol8	nucleolar protein 8	13	49653077	AK017551	70930	23	nucleic acid binding RNA binding RNA binding nucleus chromosome nucleolus nucleolus rRNA processing protein localization to nucleolus protein localization to nucleolus cellular response to leukemia inhibitory factor
1424081_at	Pcgf6	polycomb group ring finger 6	19	-47033616	BC016195	71041	41	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II protein binding nucleus nucleus chromatin remodeling regulation of transcription by RNA polymerase II protein domain specific binding PcG protein complex PcG protein complex PRC1 complex PRC1 complex negative regulation of DNA-templated transcription metal ion binding
1439495_at	Uvssa	UV stimulated scaffold protein A	5	33378695	BB476293	71101	14	RNA polymerase II complex binding RNA polymerase II complex binding nucleoplasm chromosome chromosome DNA repair transcription-coupled nucleotide-excision repair transcription-coupled nucleotide-excision repair DNA damage response response to UV response to UV protein ubiquitination
1429031_at	Zfp626	zinc finger protein 626	7	27807195	BM938256	71163	14	RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II
1453119_at	Otud1	OTU domain containing 1	2	19657730	BB530087	71198	24	cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity cellular_component proteolysis peptidase activity cysteine-type peptidase activity hydrolase activity protein K63-linked deubiquitination protein K63-linked deubiquitination
1431143_x_at	Aifm2	apoptosis-inducing factor, mitochondrion-associated 2	10	61715262, 61720648, 61715262	AK017403	71361	31	DNA binding electron-transferring-flavoprotein dehydrogenase activity electron-transferring-flavoprotein dehydrogenase activity protein binding nucleus cytoplasm cytoplasm cytoplasm mitochondrion mitochondrion mitochondrion mitochondrial outer membrane lipid droplet cytosol plasma membrane ubiquinone metabolic process apoptotic mitochondrial changes apoptotic mitochondrial changes membrane oxidoreductase activity oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor mitochondrial membrane vitamin K metabolic process positive regulation of apoptotic process positive regulation of apoptotic process flavin adenine dinucleotide binding flavin adenine dinucleotide binding negative regulation of ferroptosis regulation of cellular response to oxidative stress cellular detoxification
1436925_at	Foxn3	forkhead box N3	12	-99195093	AV228812	71375	35	cis-regulatory region sequence-specific DNA binding DNA binding DNA-binding transcription factor activity DNA-binding transcription factor activity nucleus nucleus regulation of DNA-templated transcription regulation of DNA-templated transcription cell cycle mitotic G2 DNA damage checkpoint signaling sequence-specific DNA binding negative regulation of DNA-templated transcription craniofacial suture morphogenesis
1427384_at	Chd6	chromodomain helicase DNA binding protein 6	2	-160946977	BB529459	71389	25	nucleotide binding chromatin transcription coregulator binding DNA binding DNA binding chromatin binding helicase activity ATP binding nucleus nucleus nucleoplasm chromatin organization chromatin remodeling ATP-dependent activity, acting on DNA regulation of gene expression hydrolase activity ATP hydrolysis activity histone binding cell redox homeostasis positive regulation of transcription by RNA polymerase II ATP-dependent chromatin remodeler activity ATP-dependent chromatin remodeler activity
1428579_at	Fmnl2	formin-like 2	2	52857867	AK017338	71409	27	actin binding cytosol cytoskeleton organization regulation of cell shape cellular component organization cell migration regulation of cell morphogenesis actin cytoskeleton organization cortical actin cytoskeleton organization cortical actin cytoskeleton organization small GTPase binding actin filament binding
1428773_s_at	Bcor	BCL6 interacting corepressor	X	-12036737, -12036737, -12134453	AK018370	71458	58	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II transcription regulatory region sequence-specific DNA binding blastocyst hatching transcription corepressor activity transcription corepressor activity transcription corepressor activity ubiquitin-protein transferase activity protein binding nucleus nucleus nucleus nucleoplasm chromatin organization heat shock protein binding histone deacetylase binding BCOR complex DNA-binding transcription factor binding
1436898_at	Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	4	127021300, 127021300	BI738328	71514	95	negative regulation of transcription by RNA polymerase II alternative mRNA splicing, via spliceosome alternative mRNA splicing, via spliceosome double-strand break repair via homologous recombination chromatin transcription cis-regulatory region binding activation of innate immune response immune system process nucleic acid binding DNA binding chromatin binding RNA binding RNA binding protein binding nucleus nucleus nucleoplasm cytoplasm DNA repair chromatin remodeling regulation of DNA-templated transcription mRNA processing DNA damage response RNA splicing nuclear matrix dendrite dendrite cytoplasm paraspeckles paraspeckles regulation of circadian rhythm negative regulation of circadian rhythm protein homodimerization activity histone deacetylase binding innate immune response positive regulation of sister chromatid cohesion negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II rhythmic process chromosome organization regulation of cell cycle RNA polymerase II transcription regulator complex dendritic transport of messenger ribonucleoprotein complex dendritic transport of messenger ribonucleoprotein complex dendritic transport of messenger ribonucleoprotein complex positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
1429387_at	Grap	GRB2-related adaptor protein	11	61653320	AK018457	71520	18	phosphotyrosine residue binding epidermal growth factor receptor binding nucleoplasm cytoplasm plasma membrane signal transduction COP9 signalosome membrane regulation of MAPK cascade synapse
1452952_at	Fam217b	family with sequence similarity 217, member B	2	178414533	AK018518	71532	9	molecular_function nucleoplasm cytosol biological_process
1426276_at	Ifih1	interferon induced with helicase C domain 1	2	-62595792	AY075132	71586	168	nucleotide binding immune system process DNA binding RNA binding RNA helicase activity double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding helicase activity protein binding ATP binding nucleus cytoplasm cytoplasm cytoplasm mitochondrion zinc ion binding zinc ion binding response to virus response to virus hydrolase activity ATP hydrolysis activity protein sumoylation protein domain specific binding interferon-beta production positive regulation of interferon-alpha production positive regulation of interferon-beta production positive regulation of interleukin-6 production positive regulation of tumor necrosis factor production pattern recognition receptor activity MDA-5 signaling pathway MDA-5 signaling pathway identical protein binding ribonucleoprotein complex binding negative regulation of viral genome replication innate immune response metal ion binding protein complex oligomerization defense response to virus type I interferon-mediated signaling pathway positive regulation of response to cytokine stimulus cellular response to exogenous dsRNA antiviral innate immune response antiviral innate immune response	04622
1428509_at	Myo1e	myosin IE	9	70207349	AK018649	71602	55	microfilament motor activity nucleotide binding vasculogenesis in utero embryonic development kidney development glomerular filtration cytoskeletal motor activity actin binding calmodulin binding ATP binding cytoplasm cytoplasm cytoskeleton plasma membrane microvillus brush border adherens junction nitrogen compound metabolic process endocytosis endocytosis actin filament organization lipid binding actin cytoskeleton myosin complex ATP hydrolysis activity hemopoiesis cytoplasmic vesicle cuticular plate glomerulus development glomerular basement membrane development protein-containing complex phosphatidylinositol binding post-embryonic hemopoiesis protein-containing complex binding clathrin-coated endocytic vesicle platelet-derived growth factor receptor signaling pathway actin filament binding actin filament binding anchoring junction podocyte development
1429055_at	Shtn1	shootin 1	19	-58973357	BB559293	71653	31	protein binding cytoplasm cytoplasm cytoskeleton microtubule microtubule associated complex substrate-dependent cell migration, cell extension Ras protein signal transduction multicellular organism development axonogenesis microtubule cytoskeleton kinesin binding lamellipodium filopodium axon growth cone growth cone cell leading edge cell leading edge Cdc42 protein signal transduction netrin-activated signaling pathway identical protein binding cell projection perikaryon axonal growth cone axonal growth cone axonal growth cone positive regulation of axon extension perinuclear region of cytoplasm neuron projection morphogenesis neuron projection morphogenesis cell adhesion molecule binding actin filament binding membrane depolarization cytoplasmic actin-based contraction involved in cell motility endoplasmic reticulum polarization actin filament bundle retrograde transport regulation of establishment of cell polarity regulation of establishment of cell polarity regulation of neuron migration positive regulation of neuron migration positive regulation of neuron migration positive regulation of neuron migration
1424250_a_at	Arhgef3	Rho guanine nucleotide exchange factor 3	14	27238009, 27143992, 27361388, 27336036	BC012262	71704	32	guanyl-nucleotide exchange factor activity cytoplasm positive regulation of Rho protein signal transduction intracellular signal transduction
1424524_at	Dram1	DNA-damage regulated autophagy modulator 1	10	-88322803	BC021433	71712	22	molecular_function cytoplasm lysosome lysosome autophagy apoptotic process regulation of autophagy regulation of autophagy membrane
1435137_s_at	1200015M12Rik	RIKEN cDNA 1200015M12 gene	19		BB119177	71739	9	molecular_function cellular_component biological_process
1428449_at	Gtf3c2	general transcription factor IIIC, polypeptide 2, beta	5	-31156005	AV297256	71752	29	transcription factor TFIIIC complex transcription factor TFIIIC complex RNA polymerase III general transcription initiation factor activity DNA binding nucleoplasm transcription by RNA polymerase III transcription by RNA polymerase III
1428385_at	Marchf8	membrane associated ring-CH-type finger 8	6	116338021	AK005032	71779	25	protein polyubiquitination protein polyubiquitination adaptive immune response immune system process antigen processing and presentation of peptide antigen via MHC class II antigen processing and presentation of peptide antigen via MHC class II ubiquitin-protein transferase activity ubiquitin-protein transferase activity cytoplasm lysosome lysosome endosome endoplasmic reticulum Golgi apparatus immune response zinc ion binding membrane protein ubiquitination transferase activity cytoplasmic vesicle early endosome membrane late endosome membrane MHC protein binding MHC class II protein binding negative regulation of MHC class II biosynthetic process metal ion binding ubiquitin protein ligase activity ubiquitin protein ligase activity
1452316_at	Ints12	integrator complex subunit 12	3	133091854	AK003874	71793	21	molecular_function nucleus snRNA processing integrator complex integrator complex snRNA 3'-end processing metal ion binding
1429274_at	Lypd6b	LY6/PLAUR domain containing 6B	2	49787682	AK009282	71897	18	cellular_component plasma membrane membrane acetylcholine receptor regulator activity acetylcholine receptor regulator activity side of membrane
1452257_at	Bdh1	3-hydroxybutyrate dehydrogenase, type 1	16	31428752, 31422296	BF322712	71911	43	catalytic activity 3-hydroxybutyrate dehydrogenase activity 3-hydroxybutyrate dehydrogenase activity phospholipid binding mitochondrion mitochondrion mitochondrial inner membrane mitochondrial inner membrane lipid metabolic process metabolic process steroid metabolic process membrane oxidoreductase activity intracellular membrane-bounded organelle	00072 00650 01100
1431055_a_at	Snx10	sorting nexin 10	6	51524259, 51545292, 51524083, 51544522, 51523902	AK010399	71982	37	gastric acid secretion 1-phosphatidylinositol binding nucleus nucleus cytoplasm endosome endosome endoplasmic reticulum endoplasmic reticulum centrosome cytoskeleton intracellular protein transport endocytosis endosome organization lipid binding protein transport membrane vesicle organization cellular homeostasis cell projection organization secretory granule osteoclast differentiation extrinsic component of endosome membrane phosphatidylinositol binding bone mineralization involved in bone maturation tooth eruption bone resorption bone remodeling ATPase binding establishment of localization in cell calcium ion homeostasis cilium assembly cilium assembly protein localization to cilium protein localization to centrosome apical cytoplasm ruffle assembly phosphatidylinositol phosphate binding cellular response to leukemia inhibitory factor
1436759_x_at	Cnn3	calponin 3, acidic	3	121426540	AV172168	71994	47	actin binding calmodulin binding cytosol actin filament organization microtubule binding actin cytoskeleton actin cytoskeleton dendrite actomyosin structure organization neuronal cell body dendritic spine actin filament binding postsynapse glutamatergic synapse
1433833_at	Fndc3b	fibronectin type III domain containing 3B	3	-27416134	BG064539	72007	35	endoplasmic reticulum fibroblast migration membrane substrate adhesion-dependent cell spreading positive regulation of fat cell differentiation positive regulation of fat cell differentiation negative regulation of osteoblast differentiation positive regulation of fibroblast proliferation type II pneumocyte differentiation
1419307_at	Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	15	-82221741	NM_028075	72049	108	B cell homeostasis adaptive immune response immune system process germinal center formation positive regulation of germinal center formation external side of plasma membrane external side of plasma membrane membrane positive regulation of B cell proliferation positive regulation of B cell proliferation T cell costimulation T cell costimulation T cell costimulation B cell costimulation B cell costimulation positive regulation of type II interferon production tumor necrosis factor-mediated signaling pathway signaling receptor activity T cell proliferation T cell proliferation B cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation positive regulation of T cell proliferation regulation of immune response	04060 04672 05340
1454785_at	Dusp11	dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)	6	-85942268	BE951717	72102	18	fibrillar center RNA binding polynucleotide 5'-phosphatase activity polynucleotide 5'-phosphatase activity phosphoprotein phosphatase activity protein tyrosine phosphatase activity nucleus nucleoplasm protein dephosphorylation protein tyrosine/serine/threonine phosphatase activity dephosphorylation nuclear speck hydrolase activity phosphatase activity intercellular bridge
1451079_at	Adpgk	ADP-dependent glucokinase	9	59291571	BC021526	72141	30	extracellular region endoplasmic reticulum endoplasmic reticulum carbohydrate metabolic process glucose metabolic process glucose metabolic process glucose metabolic process glycolytic process kinase activity phosphorylation transferase activity phosphotransferase activity, alcohol group as acceptor ADP-specific glucokinase activity ADP-specific glucokinase activity ADP-specific glucokinase activity metal ion binding	00010 01100
1428517_at	Wdfy3	WD repeat and FYVE domain containing 3	5	-101832952	AK012075	72145	50	autophagosome membrane beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity 1-phosphatidylinositol binding nucleus nuclear envelope nucleoplasm nucleolus cytoplasm cytoplasm autophagosome cytosol plasma membrane autophagy multicellular organism development lipid binding membrane inclusion body PML body Atg12-Atg5-Atg16 complex aggrephagy aggrephagy cell projection metal ion binding
1428357_at	Tdrp	testis development related protein	8	-13952007, -13952007	AK011462	72148	22	molecular_function nucleus nucleus cytoplasm cytosol cytosol spermatogenesis spermatogenesis intracellular membrane-bounded organelle
1424444_a_at	1600014C10Rik	RIKEN cDNA 1600014C10 gene	7	38183786, 38183216	BC019834	72244	15	molecular_function cytoplasm mitochondrion endoplasmic reticulum cytosol autophagy apoptotic process response to oxidative stress membrane mitochondrial membrane mitochondrial calcium ion homeostasis
1433768_at	Palld	palladin, cytoskeletal associated protein	8	-61514703, -61511430, -61511430, -61511430	BG071905	72333	61	stress fiber stress fiber ruffle podosome keratinocyte development epithelial cell morphogenesis actin binding nucleus nucleus cytoplasm mitochondrion cytosol cytoskeleton cytoskeleton actin filament actin filament plasma membrane plasma membrane focal adhesion focal adhesion homophilic cell adhesion via plasma membrane adhesion molecules axon guidance receptor activity cytoskeletal protein binding actin cytoskeleton cell migration Z disc Z disc lamellipodium actin cytoskeleton organization filopodium axon axon growth cone cell projection neuronal cell body neuronal cell body axonal growth cone synapse organization excitatory synapse anchoring junction
1424029_at	Tspyl4	TSPY-like 4	10	34297420	BC017540	72480	17	chromatin molecular_function chromatin binding nucleus nucleus nucleosome assembly biological_process histone binding
1428389_s_at	Wdr43	WD repeat domain 43	17	71616214	AK012043	72515	25	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) chromatin RNA polymerase II complex binding fibrillar center transcription elongation factor activity RNA binding protein binding nucleus nucleoplasm nucleolus nucleolus nucleolus rRNA processing small-subunit processome regulation of transcription elongation by RNA polymerase II ribosome biogenesis ribosomal small subunit biogenesis positive regulation of transcription by RNA polymerase I regulation of stem cell population maintenance positive regulation of rRNA processing	03008
1428768_at	Pan3	PAN3 poly(A) specific ribonuclease subunit	5	147430155	AK012409	72587	23	nucleotide binding nuclear-transcribed mRNA poly(A) tail shortening nuclear-transcribed mRNA poly(A) tail shortening deadenylation-dependent decapping of nuclear-transcribed mRNA P-body P-body RNA binding poly(A)-specific ribonuclease activity protein kinase activity protein binding ATP binding nucleus cytoplasm mRNA processing protein phosphorylation protein targeting poly(A) binding positive regulation of cytoplasmic mRNA processing body assembly positive regulation of cytoplasmic mRNA processing body assembly PAN complex PAN complex metal ion binding	03018
1428810_at	2700097O09Rik	RIKEN cDNA 2700097O09 gene	12	-55045660	AK012621	72658	20	methyltransferase activity
1430195_at	2810043O03Rik	RIKEN cDNA 2810043O03 gene	9		BF662697	72697	8	molecular_function cellular_component biological_process
1426223_at	Ttc39c	tetratricopeptide repeat domain 39C	18	12643532	BC020021	72747	17	molecular_function cellular_component otolith morphogenesis cilium assembly
1429096_at	2810455D13Rik	RIKEN cDNA 2810455D13 gene	19		AK013353	72810	7	molecular_function cellular_component biological_process
1426985_s_at	Fam76b	family with sequence similarity 76, member B	9	13827715	AV337692	72826	19	nucleus nuclear speck nuclear speck
1438969_x_at	Dhx30	DExH-box helicase 30	9	-110084318, -110084318, -110084318	BB105391	72831	35	nucleotide binding G-quadruplex RNA binding nucleic acid binding DNA helicase activity chromatin binding RNA binding RNA helicase activity RNA helicase activity RNA helicase activity double-stranded RNA binding helicase activity ATP binding intracellular anatomical structure nucleus cytoplasm cytoplasm cytoplasm mitochondrion cytosol central nervous system development hydrolase activity ribonucleoprotein granule ribosome biogenesis mitochondrial nucleoid mitochondrial large ribosomal subunit assembly
1435445_at	Ccnt2	cyclin T2	1	127774163	AV377237	72949	28	transcription coactivator binding chromatin binding protein binding nucleus nucleus nucleoplasm cytoplasm cytosol plasma membrane regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cell cycle skeletal muscle tissue development cyclin/CDK positive transcription elongation factor complex cyclin/CDK positive transcription elongation factor complex cyclin-dependent protein serine/threonine kinase regulator activity early viral transcription late viral transcription protein kinase binding positive regulation of DNA-templated transcription, elongation positive regulation of transcription elongation by RNA polymerase II positive regulation of transcription by RNA polymerase II perinuclear region of cytoplasm regulation of muscle cell differentiation cell division cyclin-dependent protein serine/threonine kinase activator activity RNA polymerase binding 7SK snRNA binding
1431050_at	Rps6ka5	ribosomal protein S6 kinase, polypeptide 5	12	-100548439	BE291900	73086	109	nucleotide binding magnesium ion binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein tyrosine kinase activity protein binding ATP binding ATP binding nucleus nucleus nucleoplasm nucleoplasm cytoplasm cytoplasm regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of DNA-templated transcription protein phosphorylation protein phosphorylation inflammatory response kinase activity phosphorylation transferase activity peptidyl-serine phosphorylation histone H3S10 kinase activity intracellular signal transduction intracellular signal transduction post-translational protein modification post-translational protein modification histone H3S28 kinase activity histone H3S28 kinase activity histone H2AS1 kinase activity negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of NF-kappaB transcription factor activity interleukin-1-mediated signaling pathway regulation of postsynapse organization regulation of postsynapse organization	04010 04722 05219
1429954_at	Clec4a3	C-type lectin domain family 4, member a3	6	122952514, 122952643	AK014135	73149	12	calcium ion binding mannose binding external side of plasma membrane carbohydrate binding carbohydrate binding antifungal innate immune response
1455433_at	Zfp942	zinc finger protein 942	17	-21926962	BM241540	73233	14	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II
1434675_at	Zfp763	zinc finger protein 763	17	-33016863	BB442939	73451	15	RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II
1454923_at	Iws1	IWS1, SUPT6 interacting protein	18	32067733	BQ175964	73473	22	molecular_function nucleus nucleus nucleoplasm chromatin remodeling mRNA processing RNA splicing regulation of mRNA export from nucleus poly(A)+ mRNA export from nucleus regulation of mRNA processing mRNA transport transcription elongation-coupled chromatin remodeling
1450234_at	Ms4a6c	membrane-spanning 4-domains, subfamily A, member 6C	19	11469367, 11469367	AF237910	73656	14	trans-Golgi network trans-Golgi network plasma membrane cell surface receptor signaling pathway membrane
1451649_a_at	Wdr75	WD repeat domain 75	1	45795165	BC004071	73674	24	RNA binding nucleus nucleolus nucleolus rRNA processing small-subunit processome ribosome biogenesis ribosomal small subunit biogenesis positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase I positive regulation of rRNA processing positive regulation of rRNA processing	03008
1429396_at	Atg16l2	autophagy related 16 like 2	7	-101289615	AK010773	73683	26	autophagosome assembly autophagosome assembly autophagosome membrane protein binding nucleoplasm cytoplasm cytosol protein transport macroautophagy phagophore assembly site membrane phagophore assembly site membrane Atg12-Atg5-Atg16 complex Atg12-Atg5-Atg16 complex Atg12-Atg5-Atg16 complex negative stranded viral RNA replication negative stranded viral RNA replication
1428781_at	Dmkn	dermokine	7	30763755, 30776404, 30763757	BI452905	73712	23	molecular_function extracellular region extracellular space extracellular space cell differentiation cornified envelope assembly cornified envelope assembly
1436506_a_at	Snhg6	small nucleolar RNA host gene 6	1	-9942024	AW988981	73824	19	molecular_function cellular_component biological_process
1435040_at	Irak3	interleukin-1 receptor-associated kinase 3	10	-120141647, -120141647	AV228493	73914	89	nucleotide binding magnesium ion binding magnesium ion binding positive regulation of cytokine production negative regulation of cytokine-mediated signaling pathway protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein binding ATP binding ATP binding nucleus nucleus nucleus cytoplasm cytoplasm cytoplasm plasma membrane protein phosphorylation protein phosphorylation apoptotic process signal transduction Toll signaling pathway response to virus positive regulation of macrophage tolerance induction negative regulation of macrophage cytokine production cytokine-mediated signaling pathway protein kinase binding negative regulation of NF-kappaB transcription factor activity response to peptidoglycan response to lipopolysaccharide negative regulation of interleukin-12 production negative regulation of interleukin-12 production negative regulation of interleukin-12 production negative regulation of interleukin-6 production negative regulation of interleukin-6 production negative regulation of tumor necrosis factor production negative regulation of tumor necrosis factor production negative regulation of tumor necrosis factor production negative regulation of toll-like receptor signaling pathway intracellular signal transduction negative regulation of protein catabolic process negative regulation of protein catabolic process protein homodimerization activity regulation of apoptotic process negative regulation of protein-containing complex disassembly regulation of protein-containing complex disassembly response to exogenous dsRNA negative regulation of MAP kinase activity negative regulation of MAP kinase activity negative regulation of MAP kinase activity negative regulation of innate immune response protein autophosphorylation protein heterodimerization activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity positive regulation of NF-kappaB transcription factor activity interleukin-1-mediated signaling pathway interleukin-1-mediated signaling pathway interleukin-1-mediated signaling pathway response to interleukin-1 cellular response to lipopolysaccharide	04210 04722
1434468_at	Otud4	OTU domain containing 4	8	79639675	BM238914	73945	29	immune system process cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity nucleus cytoplasm cytosol proteolysis peptidase activity cysteine-type peptidase activity protein deubiquitination hydrolase activity negative regulation of toll-like receptor signaling pathway negative regulation of toll-like receptor signaling pathway negative regulation of toll-like receptor signaling pathway innate immune response molecular adaptor activity K63-linked deubiquitinase activity K63-linked deubiquitinase activity K63-linked deubiquitinase activity protein K63-linked deubiquitination protein K63-linked deubiquitination protein K48-linked deubiquitination positive regulation of DNA demethylation regulation of protein K48-linked deubiquitination regulation of protein K48-linked deubiquitination negative regulation of interleukin-1-mediated signaling pathway negative regulation of interleukin-1-mediated signaling pathway negative regulation of interleukin-1-mediated signaling pathway
1429960_at	4930438A08Rik	RIKEN cDNA 4930438A08 gene	11	58274827	BB775376	73988	8	L-amino-acid oxidase activity cellular_component amino acid catabolic process polyamine oxidase activity
1433590_at	Herc3	hect domain and RLD 3	6	58831464, 58833699, 58831464	BM239854	73998	19	cytoplasm ubiquitin-dependent protein catabolic process protein ubiquitination ubiquitin protein ligase activity	04120
1429443_at	Cpne4	copine IV	9	104566700, 104569654, 104588057	AK014396	74020	22	protein binding calcium-dependent phospholipid binding calcium-dependent phospholipid binding plasma membrane metal ion binding cellular response to calcium ion
1448407_at	Vsir	V-set immunoregulatory receptor	10	60346850	BC003967	74048	56	negative regulation of T cell cytokine production protein binding plasma membrane plasma membrane plasma membrane external side of plasma membrane positive regulation of gene expression positive regulation of endopeptidase activity membrane enzyme binding positive regulation of cell migration BMP signaling pathway BMP signaling pathway positive regulation of BMP signaling pathway positive regulation of BMP signaling pathway zymogen activation negative regulation of type II interferon production negative regulation of interleukin-10 production negative regulation of interleukin-17 production negative regulation of tumor necrosis factor production identical protein binding positive regulation of regulatory T cell differentiation negative regulation of alpha-beta T cell activation stem cell differentiation stem cell differentiation regulation of immune response endopeptidase activator activity positive regulation of collagen catabolic process negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of CD4-positive, alpha-beta T cell proliferation negative regulation of CD8-positive, alpha-beta T cell proliferation positive regulation of stem cell differentiation
1424032_at	Hvcn1	hydrogen voltage-gated channel 1	5	122210286, 122209728, 122210138	BC021548	74096	68	monoatomic ion channel activity plasma membrane monoatomic ion transport response to pH response to zinc ion response to zinc ion membrane membrane apical plasma membrane voltage-gated monoatomic cation channel activity voltage-gated proton channel activity voltage-gated proton channel activity voltage-gated proton channel activity positive regulation of superoxide anion generation monoatomic ion transmembrane transport monoatomic ion channel complex identical protein binding identical protein binding regulation of intracellular pH intracellular pH elevation transmembrane transport regulation of acrosome reaction cellular response to zinc ion cellular response to pH proton transmembrane transport proton transmembrane transport proton transmembrane transport regulation of reactive oxygen species biosynthetic process
1428141_at	Gga2	golgi associated, gamma adaptin ear containing, ARF binding protein 2	7	-121986721	AK004632	74105	26	protein binding endosome Golgi apparatus trans-Golgi network trans-Golgi network intracellular protein transport Golgi to plasma membrane transport protein transport membrane vesicle-mediated transport clathrin-coated vesicle small GTPase binding small GTPase binding protein localization to cell surface protein localization to cell surface phosphatidylinositol binding Golgi to plasma membrane protein transport ubiquitin binding	04142
1447432_s_at	Zfp263	zinc finger protein 263	16	3744098	AI326880	74120	26	negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding nucleus nucleus regulation of DNA-templated transcription regulation of transcription by RNA polymerase II sequence-specific DNA binding negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II metal ion binding sequence-specific double-stranded DNA binding
1434949_at	Armc8	armadillo repeat containing 8	9	-99478390, -99518244	BE995635	74125	26	ubiquitin ligase complex molecular_function nucleus nucleoplasm cytoplasm cytosol GID complex proteasome-mediated ubiquitin-dependent protein catabolic process intracellular membrane-bounded organelle
1443609_s_at	Syvn1	synovial apoptosis inhibitor 1, synoviolin	19	6047144, 6046575	C85322	74126	87	ubiquitin ligase complex Hrd1p ubiquitin ligase ERAD-L complex in utero embryonic development immature B cell differentiation protein binding nucleoplasm cytoplasm endoplasmic reticulum smooth endoplasmic reticulum ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process response to unfolded protein multicellular organism development endomembrane system membrane protein ubiquitination transferase activity protein catabolic process retrograde protein transport, ER to cytosol ERAD pathway ERAD pathway ERAD pathway Derlin-1 retrotranslocation complex endoplasmic reticulum quality control compartment endoplasmic reticulum quality control compartment endoplasmic reticulum quality control compartment metal ion binding protein stabilization protein stabilization unfolded protein binding protein-folding chaperone binding ATPase binding ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin protein ligase activity ubiquitin protein ligase activity intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress protein K48-linked ubiquitination negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway ubiquitin-specific protease binding	04120 04141
1428248_at	Nfx1	nuclear transcription factor, X-box binding 1	4	40970942, 40970905	AK005038	74164	34	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific nucleic acid binding DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleoplasm nucleolus cytosol plasma membrane zinc ion binding transferase activity negative regulation of MHC class II biosynthetic process metal ion binding protein autoubiquitination ubiquitin protein ligase activity
1428700_at	P2ry13	purinergic receptor P2Y, G-protein coupled 13	3	-59207893	AK008013	74191	44	G protein-coupled receptor activity endoplasmic reticulum plasma membrane signal transduction G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway negative regulation of adenylate cyclase activity membrane G protein-coupled purinergic nucleotide receptor activity G protein-coupled purinergic nucleotide receptor activity cellular response to organic cyclic compound	04080
1436421_s_at	Arpc5l	actin related protein 2/3 complex, subunit 5-like	2	39008138	BB403233	74192	25	actin binding cytoplasm cytoplasm cytoskeleton Arp2/3 protein complex Arp2/3 protein complex actin cytoskeleton cell migration regulation of actin filament polymerization Arp2/3 complex-mediated actin nucleation Arp2/3 complex-mediated actin nucleation synapse synapse actin filament binding glutamatergic synapse glutamatergic synapse	04666 04810 05100
1455700_at	Mterf2	mitochondrial transcription termination factor 2	10	-85119432, -85119440	BB359043	74238	16	nucleic acid binding DNA binding double-stranded DNA binding mitochondrion mitochondrion mitochondrial matrix regulation of DNA-templated transcription termination of mitochondrial transcription mitochondrial nucleoid
1429201_at	Cyld	CYLD lysine 63 deubiquitinase	8	88697027	AK013508	74256	137	immune system process cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity cysteine-type deubiquitinase activity protein binding cytoplasm centrosome spindle cytosol cytosol cytoskeleton microtubule cytoplasmic microtubule plasma membrane proteolysis regulation of mitotic cell cycle regulation of mitotic cell cycle peptidase activity cysteine-type peptidase activity zinc ion binding cytoplasmic side of plasma membrane regulation of tumor necrosis factor-mediated signaling pathway regulation of tumor necrosis factor-mediated signaling pathway membrane Wnt signaling pathway protein deubiquitination protein deubiquitination protein deubiquitination hydrolase activity protein kinase binding midbody negative regulation of NF-kappaB transcription factor activity negative regulation of NF-kappaB transcription factor activity ciliary basal body cell projection CD4-positive or CD8-positive, alpha-beta T cell lineage commitment regulation of protein binding innate immune response regulation of B cell differentiation positive regulation of T cell differentiation negative regulation of JNK cascade negative regulation of JNK cascade metal ion binding homeostasis of number of cells regulation of inflammatory response negative regulation of inflammatory response regulation of T cell receptor signaling pathway positive regulation of T cell receptor signaling pathway regulation of necroptotic process regulation of necroptotic process K63-linked deubiquitinase activity K63-linked deubiquitinase activity K63-linked deubiquitinase activity Met1-linked polyubiquitin deubiquitinase activity proline-rich region binding necroptotic process necroptotic process necroptotic process regulation of microtubule cytoskeleton organization protein K63-linked deubiquitination protein K63-linked deubiquitination negative regulation of canonical Wnt signaling pathway ciliary tip ripoptosome assembly involved in necroptotic process negative regulation of non-canonical NF-kappaB signal transduction regulation of cilium assembly negative regulation of p38MAPK cascade negative regulation of p38MAPK cascade positive regulation of protein localization protein linear deubiquitination protein linear deubiquitination K48-linked deubiquitinase activity negative regulation of interleukin-18-mediated signaling pathway positive regulation of extrinsic apoptotic signaling pathway positive regulation of extrinsic apoptotic signaling pathway regulation of intrinsic apoptotic signaling pathway regulation of intrinsic apoptotic signaling pathway	04380 04622
1451776_s_at	Hopx	HOP homeobox	5	-77086985, -77086985	BC024546	74318	162	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II trophectodermal cell differentiation trophectodermal cell differentiation DNA binding protein binding nucleus nucleus nucleus cytoplasm regulation of transcription by RNA polymerase II multicellular organism development heart development regulation of heart contraction cell differentiation histone deacetylase regulator activity regulation of protein binding positive regulation of skeletal muscle tissue regeneration negative regulation of cell differentiation lung alveolus development chaperone-mediated protein complex assembly positive regulation of striated muscle cell differentiation positive regulation of gap junction assembly
1453485_s_at	Mettl23	methyltransferase like 23	11	116843514	AK016897	74319	18	female pronucleus male pronucleus protein binding nucleus nucleus nucleoplasm cytoplasm cytoplasm cytoplasm chromatin organization multicellular organism development methyltransferase activity S-adenosylmethionine-dependent methyltransferase activity protein-lysine N-methyltransferase activity transferase activity peptidyl-lysine methylation heat shock protein binding methylation protein-containing complex protein-arginine omega-N asymmetric methyltransferase activity histone H3R17 methyltransferase activity histone methyltransferase activity epigenetic programming in the zygotic pronuclei epigenetic programing of male pronucleus positive regulation of transcription by RNA polymerase II cognition DNA-binding transcription factor binding
1428663_at	Sgms2	sphingomyelin synthase 2	3	-131318985, -131318985, -131318985, -131318985, -131318985, -131318985	AK017223	74442	71	Golgi membrane Golgi membrane ceramide phosphoethanolamine synthase activity nucleoplasm Golgi apparatus plasma membrane plasma membrane lipid metabolic process sphingolipid metabolic process sphingomyelin biosynthetic process sphingomyelin biosynthetic process sphingomyelin biosynthetic process sphingomyelin biosynthetic process membrane kinase activity phosphorylation transferase activity phosphotransferase activity, for other substituted phosphate groups regulation of bone mineralization sphingomyelin synthase activity sphingomyelin synthase activity sphingomyelin synthase activity sphingomyelin synthase activity ceramide biosynthetic process ceramide biosynthetic process ceramide cholinephosphotransferase activity ceramide cholinephosphotransferase activity ceramide cholinephosphotransferase activity ceramide phosphoethanolamine biosynthetic process	00600 01100
1430005_a_at	Batf2	basic leucine zipper transcription factor, ATF-like 2	19	6164438	AK016990	74481	32	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity nucleus nucleus regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cell differentiation defense response to protozoan myeloid dendritic cell differentiation RNA polymerase II transcription regulator complex
1447522_s_at	Tnks2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	19	36834231	AI662480	74493	33	protein polyubiquitination pericentriolar material telomere maintenance chromosome, telomeric region NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity nucleus nucleus nuclear envelope chromosome cytoplasm cytoplasm Golgi apparatus membrane Wnt signaling pathway transferase activity glycosyltransferase activity nucleotidyltransferase activity enzyme binding multicellular organism growth regulation of multicellular organism growth metal ion binding perinuclear region of cytoplasm protein localization to chromosome, telomeric region protein localization to chromosome, telomeric region protein poly-ADP-ribosylation protein auto-ADP-ribosylation positive regulation of canonical Wnt signaling pathway positive regulation of canonical Wnt signaling pathway positive regulation of telomere capping positive regulation of telomere capping negative regulation of telomere maintenance via telomere lengthening NAD+-protein ADP-ribosyltransferase activity
1429570_at	Mlkl	mixed lineage kinase domain-like	8	-111311797	AK018636	74568	217	nucleotide binding protein binding ATP binding ATP binding nucleus cytoplasm cytoplasm cytosol plasma membrane plasma membrane protein phosphorylation cell surface receptor signaling pathway programmed cell death membrane protein kinase binding cell junction identical protein binding protein-containing complex binding defense response to virus defense response to virus protein homotrimerization necroptotic process necroptotic process necroptotic signaling pathway necroptotic signaling pathway execution phase of necroptosis execution phase of necroptosis execution phase of necroptosis
1430143_at	4930426D05Rik	RIKEN cDNA 4930426D05 gene	18	21651564	AK015205	74644	11	molecular_function cellular_component biological_process
1433756_at	S100pbp	S100P binding protein	4	-129148001, -129148001	BI452674	74648	16	molecular_function nucleus nucleus cytosol cytosol biological_process nuclear speck calcium-dependent protein binding calcium-dependent protein binding
1429319_at	Rhoh	ras homolog family member H	5	65861219, 65863583	BM243660	74734	35	nucleotide binding immunological synapse GTPase activity GTPase activity protein binding GTP binding GTP binding cytoplasm cytoplasm plasma membrane plasma membrane actin filament organization signal transduction small GTPase-mediated signal transduction membrane kinase inhibitor activity protein kinase binding T cell differentiation negative regulation of canonical NF-kappaB signal transduction mast cell activation positive regulation of T cell differentiation	04670
1425294_at	Slamf8	SLAM family member 8	1	-172581376	BC024587	74748	18	leukocyte chemotaxis involved in inflammatory response leukocyte chemotaxis involved in inflammatory response B-1 B cell lineage commitment negative regulation of macrophage chemotaxis membrane regulation of NAD(P)H oxidase activity signaling receptor activity signaling receptor activity defense response to bacterium identical protein binding regulation of kinase activity regulation of B cell differentiation regulation of B cell differentiation negative regulation of respiratory burst involved in inflammatory response cellular response to xenobiotic stimulus negative regulation of monocyte chemotaxis phagosome acidification negative regulation of neutrophil migration negative regulation of dendritic cell chemotaxis
1435465_at	Kbtbd11	kelch repeat and BTB (POZ) domain containing 11	8	15011024	AW049906	74901	22	molecular_function cellular_component biological_process
1455169_at	Rab11fip2	RAB11 family interacting protein 2 (class I)	19	-59902883, -59902883	BG076094	74998	25	phagocytic cup phagocytic cup nucleoplasm endosome endosome plasma membrane phagocytosis protein transport membrane protein kinase binding establishment of cell polarity small GTPase binding TRAM-dependent toll-like receptor 4 signaling pathway insulin secretion involved in cellular response to glucose stimulus identical protein binding protein homodimerization activity intracellular membrane-bounded organelle positive regulation of GTPase activity regulated exocytosis regulated exocytosis positive regulation of protein localization to plasma membrane	04144
1433514_at	Etnk1	ethanolamine kinase 1	6	143167229	BG066916	75320	35	nucleotide binding ethanolamine kinase activity ethanolamine kinase activity ATP binding cytoplasm cytoplasm lipid metabolic process phosphatidylethanolamine biosynthetic process phosphatidylethanolamine biosynthetic process phospholipid biosynthetic process kinase activity phosphorylation transferase activity	00564 01100
1453266_at	Zbtb4	zinc finger and BTB domain containing 4	11	69765911	BB767069	75580	25	negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding nucleus nucleoplasm chromosome cytosol regulation of DNA-templated transcription DNA damage response methyl-CpG binding methyl-CpNpG binding nuclear body protein kinase binding protein homodimerization activity sequence-specific DNA binding negative regulation of DNA-templated transcription metal ion binding
1424713_at	Calml4	calmodulin-like 4	9	62858103	AY061807	75600	20	calcium ion binding calcium ion binding microvillus enzyme regulator activity myosin head/neck binding brush border assembly
1449303_at	Sesn3	sestrin 3	9	14276300	NM_030261	75747	34	protein binding nucleus cytoplasm positive regulation of macroautophagy oxidoreductase activity oxidoreductase activity, acting on peroxide as acceptor TORC2 complex response to insulin response to insulin cellular response to amino acid starvation TORC2 signaling cellular response to glucose starvation glucose homeostasis glucose homeostasis regulation of insulin receptor signaling pathway regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GATOR2 complex leucine binding cellular response to amino acid stimulus cellular response to leucine regulation of response to reactive oxygen species negative regulation of TORC1 signaling negative regulation of TORC1 signaling negative regulation of TORC1 signaling cellular response to leucine starvation	04115
1428651_at	Klhl24	kelch-like 24	16	20097553	AK004187	75785	20	cytoplasm adherens junction protein ubiquitination desmosome Cul3-RING ubiquitin ligase complex cell projection intermediate filament organization protein autoubiquitination anchoring junction regulation of kainate selective glutamate receptor activity
1435374_at	Cdyl2	chromodomain protein, Y chromosome-like 2	8	-116568723	BG071670	75796	20	transcription corepressor activity nucleus nucleus methylated histone binding
1427428_at	Clec4g	C-type lectin domain family 4, member g	8	-3716070	BC025069	75863	24	virus receptor activity T cell mediated immunity negative regulation of T cell mediated immunity negative regulation of T cell mediated immunity protein binding mannose binding plasma membrane plasma membrane immune response external side of plasma membrane membrane carbohydrate binding carbohydrate binding polysaccharide binding immature T cell proliferation in thymus negative regulation of immature T cell proliferation in thymus negative regulation of T cell proliferation biological process involved in interspecies interaction between organisms alpha-beta T cell proliferation negative regulation of alpha-beta T cell proliferation symbiont entry into host cell fructose binding carbohydrate derivative binding virus coreceptor activity positive regulation of viral life cycle
1427902_at	Srrm2	serine/arginine repetitive matrix 2	17	23803224, 23803186	BQ176063	75956	36	mRNA splicing, via spliceosome mRNA binding nucleus spliceosomal complex mRNA processing RNA splicing Cajal body nuclear speck C2H2 zinc finger domain binding U2-type precatalytic spliceosome U2-type catalytic step 2 spliceosome catalytic step 2 spliceosome
1428694_at	Mir17hg	Mir17 host gene (non-protein coding)	14	115044389	AK017164	75957	35	molecular_function cellular_component response to wounding
1434236_at	Zdhhc20	zinc finger, DHHC domain containing 20	14	-57832701	BB667600	75965	21	Golgi membrane cytoplasm endoplasmic reticulum endoplasmic reticulum Golgi apparatus Golgi apparatus plasma membrane protein targeting to membrane zinc ion binding membrane synaptic vesicle maturation palmitoyltransferase activity transferase activity acyltransferase activity peptidyl-L-cysteine S-palmitoylation peptidyl-L-cysteine S-palmitoylation protein palmitoylation protein-cysteine S-palmitoyltransferase activity protein-cysteine S-palmitoyltransferase activity intracellular membrane-bounded organelle positive regulation by host of viral process metal ion binding
1452970_at	Zmym2	zinc finger, MYM-type 2	14	56886602, 56886602, 56886842	AK017929	76007	42	protein binding nucleus zinc ion binding PML body ubiquitin conjugating enzyme binding negative regulation of DNA-templated transcription metal ion binding
1429672_at	5830407E08Rik	RIKEN cDNA 5830407E08 gene	2		BB234837	76013	7	molecular_function cellular_component biological_process
1436491_at	Gm11346	X-linked lymphocyte-regulated 5 pseudogene	13	-24598124	BB387637	76024	8
1441317_x_at	Jakmip1	janus kinase and microtubule interacting protein 1	5	37050856, 37085235	BB316060	76071	21	RNA binding cytoplasm cytoskeleton microtubule microtubule binding protein transport microtubule cytoskeleton membrane kinesin binding kinase binding GABA receptor binding GABA receptor binding cognition ribonucleoprotein complex
1428457_at	Ttpal	tocopherol (alpha) transfer protein-like	2	163602313, 163607211	AK014262	76080	15	molecular_function biological_process phosphatidylinositol bisphosphate binding
1435959_at	Arhgap15	Rho GTPase activating protein 15	2	43787354, 43748823, 43748823	BM246535	76117	24	GTPase activator activity nucleoplasm cytoplasm cytoplasm plasma membrane signal transduction regulation of cell shape membrane regulation of GTPase activity
1428696_at	Rftn1	raftlin lipid raft linker 1	17	-49993306	AK009372	76438	20	membrane raft assembly T cell antigen processing and presentation double-stranded RNA binding cytoplasm endosome plasma membrane membrane protein transport into membrane raft positive regulation of interleukin-17 production protein-containing complex dsRNA transport toll-like receptor 3 signaling pathway positive regulation of growth rate response to exogenous dsRNA membrane raft T cell receptor signaling pathway B cell receptor signaling pathway protein localization to membrane raft
1456542_s_at	Qrsl1	glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1	10	-43874189	BB517855	76563	19	nucleotide binding catalytic activity ATP binding mitochondrion mitochondrion mitochondrion translation ligase activity glutamyl-tRNA(Gln) amidotransferase complex glutamyl-tRNA(Gln) amidotransferase complex regulation of protein stability mitochondrial translation mitochondrial translation mitochondrial translation glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity glutaminyl-tRNAGln biosynthesis via transamidation glutaminyl-tRNAGln biosynthesis via transamidation
1453568_at	Dapl1	death associated protein-like 1	2	59484652	BE633038	76747	20	cellular_component apoptotic process negative regulation of autophagy cell differentiation cellular response to amino acid starvation death domain binding apoptotic signaling pathway negative regulation of CD8-positive, alpha-beta T cell activation
1435274_at	Spopl	speckle-type BTB/POZ protein-like	2	-23510053	BQ175341	76857	26	nucleus nucleus cytoplasm regulation of proteolysis negative regulation of protein ubiquitination Cul3-RING ubiquitin ligase complex ubiquitin protein ligase binding proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process
1417290_at	Lrg1	leucine-rich alpha-2-glycoprotein 1	17	-56119677	NM_029796	76905	52	positive regulation of endothelial cell proliferation positive regulation of endothelial cell proliferation type II transforming growth factor beta receptor binding transforming growth factor beta receptor binding voltage-gated potassium channel activity extracellular space extracellular space voltage-gated potassium channel complex response to bacterium positive regulation of epithelial to mesenchymal transition positive regulation of keratinocyte proliferation positive regulation of keratinocyte proliferation positive regulation of transforming growth factor beta receptor signaling pathway positive regulation of transforming growth factor beta receptor signaling pathway type I transforming growth factor beta receptor binding wound healing, spreading of epidermal cells wound healing, spreading of epidermal cells intracellular membrane-bounded organelle transmembrane transporter binding positive regulation of angiogenesis positive regulation of angiogenesis positive regulation of angiogenesis positive regulation of angiogenesis brown fat cell differentiation keratinocyte migration keratinocyte migration positive regulation of epithelial cell proliferation involved in wound healing positive regulation of epithelial cell proliferation involved in wound healing leukocyte adhesion to vascular endothelial cell leukocyte adhesion to vascular endothelial cell potassium channel activator activity
1428207_at	Bcl7a	B cell CLL/lymphoma 7A	5	123344447	AK014498	77045	35	chromatin molecular_function chromatin remodeling regulation of transcription by RNA polymerase II positive regulation of cell population proliferation SWI/SNF complex SWI/SNF complex SWI/SNF complex regulation of mitotic metaphase/anaphase transition negative regulation of cell differentiation regulation of G0 to G1 transition GBAF complex positive regulation of stem cell population maintenance regulation of G1/S transition of mitotic cell cycle positive regulation of double-strand break repair regulation of nucleotide-excision repair
1428531_at	Ints7	integrator complex subunit 7	1	191575635	BB457797	77065	26	DNA damage checkpoint signaling molecular_function nucleus chromosome cytoplasm DNA damage response snRNA processing nuclear body integrator complex integrator complex snRNA 3'-end processing cellular response to ionizing radiation
1426978_at	Klhl2	kelch-like 2, Mayven	8	-64739674	AW682368	77113	23	stress fiber actin binding cytoplasm cytoskeleton actin cytoskeleton protein ubiquitination Cul3-RING ubiquitin ligase complex identical protein binding protein homodimerization activity cell projection ubiquitin ligase-substrate adaptor activity
1454967_at	Crebrf	CREB3 regulatory factor	17	26715649	BM246522	77128	26	negative regulation of transcription by RNA polymerase II RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity nucleus nucleus nucleoplasm cytoplasm regulation of DNA-templated transcription regulation of transcription by RNA polymerase II response to unfolded protein nuclear body nuclear body response to endoplasmic reticulum stress maternal behavior maternal behavior positive regulation of protein catabolic process positive regulation of transcription by RNA polymerase II negative regulation of endoplasmic reticulum unfolded protein response negative regulation of glucocorticoid mediated signaling pathway negative regulation of glucocorticoid mediated signaling pathway positive regulation of prolactin signaling pathway
1428407_at	Hnrnpa0	heterogeneous nuclear ribonucleoprotein A0	13	-58125878	BG073366	77134	28	nucleic acid binding RNA binding mRNA binding nucleus nucleus nucleoplasm inflammatory response protein kinase binding response to lipopolysaccharide mRNA 3'-UTR AU-rich region binding mRNA 3'-UTR AU-rich region binding synapse synapse 3'-UTR-mediated mRNA stabilization 3'-UTR-mediated mRNA stabilization ribonucleoprotein complex
1434084_at	Zfp266	zinc finger protein 266	9	-20495068	BF142017	77519	22	RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific nucleus regulation of transcription by RNA polymerase II
1451574_at	Bcl9	B cell CLL/lymphoma 9	3	-97203661	BC019641	77578	45	transcription coactivator activity nucleus cytoplasm Golgi apparatus Golgi apparatus cis-Golgi network cis-Golgi network transcription by RNA polymerase II beta-catenin binding beta-catenin binding myotube differentiation involved in skeletal muscle regeneration Wnt signaling pathway sarcoplasm somatic stem cell population maintenance skeletal muscle cell differentiation myoblast differentiation positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II canonical Wnt signaling pathway canonical Wnt signaling pathway beta-catenin-TCF complex beta-catenin-TCF complex
1427532_at	Trat1	T cell receptor associated transmembrane adaptor 1	16	-48730773	BB622792	77647	15	negative regulation of receptor recycling negative regulation of receptor recycling adaptive immune response immune system process molecular_function plasma membrane membrane centriolar satellite T cell receptor complex T cell receptor complex positive regulation of calcium-mediated signaling positive regulation of T cell receptor signaling pathway positive regulation of T cell receptor signaling pathway negative regulation of transport mitotic spindle
1434105_at	Epm2aip1	EPM2A interacting protein 1	9	111271844	AV340515	77781	23	protein binding nucleus cytoplasm endoplasmic reticulum glycogen biosynthetic process response to insulin identical protein binding positive regulation of glycogen biosynthetic process positive regulation of glycogen biosynthetic process cytoplasmic side of endoplasmic reticulum membrane positive regulation of glycogen (starch) synthase activity
1429088_at	Lbh	limb-bud and heart	17	72918304	AK007400	77889	32	nucleus nucleus nucleus cytoplasm regulation of DNA-templated transcription multicellular organism development regulation of gene expression mammary gland development protein-containing complex negative regulation of intracellular estrogen receptor signaling pathway regulation of MAPK cascade negative regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription mammary gland epithelial cell differentiation positive regulation of somatic stem cell population maintenance positive regulation of somatic stem cell division positive regulation of mammary stem cell proliferation negative regulation of stem cell differentiation
1421144_at	Rpgrip1	retinitis pigmentosa GTPase regulator interacting protein 1	14	52110902	NM_023879	77945	48	protein binding cilium axoneme visual perception thromboxane A2 receptor binding photoreceptor connecting cilium photoreceptor connecting cilium eye photoreceptor cell development cell projection neuron projection retinal rod cell development response to stimulus retina development in camera-type eye neural precursor cell proliferation non-motile cilium photoreceptor distal connecting cilium non-motile cilium assembly
1438018_at	Hook1	hook microtubule tethering protein 1	4	95967378	BB463518	77963	34	actin binding protein binding cytoplasm cytoplasm centrosome cytoskeleton microtubule Golgi organization endosome organization lysosome organization multicellular organism development spermatogenesis spermatid development microtubule binding microtubule binding microtubule binding endosome to lysosome transport protein transport microtubule cytoskeleton cell differentiation cytoskeleton-dependent intracellular transport cytoskeleton-dependent intracellular transport HOPS complex cytoplasmic microtubule organization cytoplasmic microtubule organization identical protein binding protein homodimerization activity early endosome to late endosome transport dynein light intermediate chain binding FHF complex manchette assembly protein localization to perinuclear region of cytoplasm
1424256_at	Rdh12	retinol dehydrogenase 12	12	79208912	BC016204	77974	29	photoreceptor inner segment NAD-retinol dehydrogenase activity NAD-retinol dehydrogenase activity lipid metabolic process visual perception visual perception oxidoreductase activity retinol metabolic process retinol metabolic process response to stimulus NADP-retinol dehydrogenase activity cellular detoxification of aldehyde cellular detoxification of aldehyde	00830 01100
1428789_at	Ralgps2	Ral GEF with PH domain and SH3 binding motif 2	1	-156804165, -156804165	AK008856	78255	30	guanyl-nucleotide exchange factor activity guanyl-nucleotide exchange factor activity cytoplasm plasma membrane plasma membrane small GTPase-mediated signal transduction Ras protein signal transduction membrane positive regulation of GTPase activity
1428004_at	Snrnp25	small nuclear ribonucleoprotein 25 (U11/U12)	11	32205414	BC028766	78372	17	mRNA splicing, via spliceosome molecular_function nucleus nucleoplasm spliceosomal complex U12-type spliceosomal complex U12-type spliceosomal complex cytosol mRNA processing biological_process RNA splicing intercellular bridge
1422952_at	Sapcd1	suppressor APC domain containing 1	17	-35025972	NM_023893	78376	16	molecular_function cellular_component biological_process
1448618_at	Mvp	major vault protein	7	-126986859	NM_080638	78388	40	nucleus nucleus cytoplasm cytoplasm cytosol cytoskeleton cell population proliferation protein kinase binding protein phosphatase binding negative regulation of protein autophosphorylation ERBB signaling pathway negative regulation of epidermal growth factor receptor signaling pathway identical protein binding perinuclear region of cytoplasm negative regulation of protein tyrosine kinase activity protein activation cascade ribonucleoprotein complex
1427469_at	Helz	helicase with zinc finger domain	11	107547932	BI251153	78455	28	nucleotide binding RNA binding helicase activity protein binding ATP binding nucleus cytosol hydrolase activity regulatory ncRNA-mediated post-transcriptional gene silencing P granule metal ion binding
1437249_at	Skap1	src family associated phosphoprotein 1	11	96464590	BG075562	78473	28	immunological synapse positive regulation of cell-matrix adhesion adaptive immune response immune system process positive regulation of adaptive immune response protein binding nucleus nucleoplasm cytoplasm cytoplasm cytosol cytosol plasma membrane plasma membrane plasma membrane cell-cell junction membrane protein kinase binding protein phosphatase binding protein-containing complex positive regulation of integrin activation positive regulation of cell-cell adhesion mediated by integrin positive regulation of heterotypic cell-cell adhesion T cell receptor complex SH2 domain binding plasma membrane raft protein-containing complex binding positive regulation of cell adhesion positive regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II T cell receptor signaling pathway protein localization to plasma membrane positive regulation of leukocyte cell-cell adhesion
1435698_at	Rictor	RPTOR independent companion of MTOR, complex 2	15	6708380	BQ176694	78757	280	regulation of protein phosphorylation positive regulation of endothelial cell proliferation protein binding cytoskeleton organization multicellular organism development embryo development ending in birth or egg hatching regulation of gene expression peptidyl-serine phosphorylation protein kinase binding actin cytoskeleton organization positive regulation of cell growth positive regulation of actin filament polymerization cellular response to nutrient levels TOR signaling TORC2 complex TORC2 complex TORC2 complex positive regulation of TOR signaling regulation of actin cytoskeleton organization regulation of peptidyl-serine phosphorylation TORC2 signaling TORC2 signaling regulation of phosphorylation ribosome binding negative regulation of apoptotic process regulation of GTPase activity protein serine/threonine kinase activator activity protein serine/threonine kinase activator activity regulation of inflammatory response positive regulation of peptidyl-tyrosine phosphorylation regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction molecular adaptor activity regulation of establishment of cell polarity	04150
1429612_at	Eml4	echinoderm microtubule associated protein like 4	17	83350930, 83350940	AK019611	78798	26	microtubule cytoskeleton organization cytoplasm microtubule organizing center cytosol cytoskeleton microtubule negative regulation of microtubule depolymerization cell cycle mitotic metaphase chromosome alignment microtubule binding attachment of spindle microtubules to kinetochore microtubule cytoskeleton microtubule cytoskeleton midbody alpha-tubulin binding protein self-association beta-tubulin binding cell division mitotic spindle mitotic spindle
1452815_at	P2ry10	purinergic receptor P2Y, G-protein coupled 10	X	107088491, 107089332	AK020001	78826	15	G protein-coupled receptor activity G protein-coupled receptor activity plasma membrane signal transduction G protein-coupled receptor signaling pathway membrane positive regulation of Rho protein signal transduction	04080
1434758_at	Crispld2	cysteine-rich secretory protein LCCL domain containing 2	8	119992437	BB745401	78892	25	glycosaminoglycan binding glycosaminoglycan binding extracellular region extracellular space heparin binding transport vesicle extracellular matrix organization extracellular matrix face morphogenesis
1448376_at	Wrnip1	Werner helicase interacting protein 1	13	32802029	NM_030215	78903	28	nucleotide binding DNA synthesis involved in DNA repair DNA synthesis involved in DNA repair chromosome, telomeric region immune system process DNA binding protein binding ATP binding nucleus nucleus nucleus cytoplasm DNA replication DNA-templated DNA replication DNA repair DNA damage response enzyme activator activity hydrolase activity ATP hydrolysis activity single-stranded DNA helicase activity regulation of DNA-templated DNA replication initiation identical protein binding innate immune response metal ion binding perinuclear region of cytoplasm
1416897_at	Parp9	poly (ADP-ribose) polymerase family, member 9	16	35938469	NM_030253	80285	24	DNA damage checkpoint signaling negative regulation of transcription by RNA polymerase II positive regulation of defense response to virus by host immune system process transcription corepressor activity transcription corepressor activity NAD+ ADP-ribosyltransferase activity NAD+ ADP-ribosyltransferase activity enzyme inhibitor activity nucleus nucleus nucleoplasm cytoplasm cytoplasm mitochondrion cytosol DNA repair double-strand break repair DNA damage response post-transcriptional regulation of gene expression negative regulation of gene expression negative regulation of gene expression transferase activity glycosyltransferase activity nucleotidyltransferase activity enzyme binding protein-containing complex positive regulation of chromatin binding histone binding positive regulation of tyrosine phosphorylation of STAT protein negative regulation of catalytic activity ubiquitin-like protein ligase binding ubiquitin-like protein ligase binding innate immune response positive regulation of DNA-templated transcription defense response to virus regulation of response to type II interferon positive regulation of type II interferon-mediated signaling pathway positive regulation of type II interferon-mediated signaling pathway positive regulation of type II interferon-mediated signaling pathway protein poly-ADP-ribosylation ADP-D-ribose binding site of DNA damage STAT family protein binding NAD+-protein-C-terminal glycine ADP-ribosyltransferase activity positive regulation of protein localization to nucleus NAD+-protein ADP-ribosyltransferase activity
1439610_at	Rab27b	RAB27B, member RAS oncogene family	18	-69979130, -69979130	BE980253	80718	68	nucleotide binding GTPase activity GTPase activity G protein activity protein binding GTP binding GTP binding GTP binding endosome late endosome Golgi apparatus Golgi apparatus Golgi stack exocytosis membrane apical plasma membrane apical plasma membrane hydrolase activity regulation of exocytosis GDP binding protein domain specific binding trans-Golgi network transport vesicle secretory granule synaptic vesicle membrane myosin V binding multivesicular body membrane melanosome melanosome zymogen granule membrane positive regulation of exocytosis positive regulation of exocytosis synaptic vesicle endocytosis exocytic vesicle multivesicular body sorting pathway anterograde axonal protein transport	04972
1421408_at	Igsf6	immunoglobulin superfamily, member 6	7	-121064066	NM_030691	80719	13	molecular_function cellular_component biological_process membrane
1446957_s_at	N4bp1	NEDD4 binding protein 1	8	-86841138	C81621	80750	30	negative regulation of cytokine production immune system process RNA binding mRNA binding nuclease activity RNA nuclease activity protein binding nucleus nucleus nucleolus cytoplasm cytosol PML body PML body hydrolase activity negative regulation of protein ubiquitination negative regulation of protein ubiquitination negative regulation of proteasomal ubiquitin-dependent protein catabolic process negative regulation of proteasomal ubiquitin-dependent protein catabolic process cellular response to UV cellular response to UV ubiquitin binding negative regulation of viral genome replication innate immune response regulation of innate immune response
1417688_at	Fam20c	FAM20C, golgi associated secretory pathway kinase	5	138755080	NM_030565	80752	53	Golgi membrane nucleotide binding skeletal system development protease binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity calcium ion binding ATP binding extracellular region extracellular space extracellular space extracellular space nucleoplasm cytoplasm endoplasmic reticulum Golgi apparatus Golgi apparatus protein phosphorylation protein phosphorylation protein phosphorylation membrane kinase activity phosphorylation transferase activity manganese ion binding positive regulation of bone mineralization biomineral tissue development osteoclast maturation regulation of fibroblast growth factor receptor signaling pathway protein self-association positive regulation of osteoblast differentiation protein autophosphorylation metal ion binding regulation of phosphorus metabolic process enamel mineralization enamel mineralization odontoblast differentiation dentinogenesis
1451426_at	Dhx58	DExH-box helicase 58	11	-100694883	AF316999	80861	39	nucleotide binding immune system process cytoplasmic pattern recognition receptor signaling pathway DNA binding RNA binding RNA helicase activity double-stranded RNA binding double-stranded RNA binding double-stranded RNA binding single-stranded RNA binding single-stranded RNA binding helicase activity ATP binding cytoplasm cytoplasm zinc ion binding zinc ion binding response to virus response to bacterium hydrolase activity ATP hydrolysis activity negative regulation of type I interferon production negative regulation of type I interferon production positive regulation of type I interferon production negative regulation of MDA-5 signaling pathway negative regulation of RIG-I signaling pathway negative regulation of RIG-I signaling pathway negative regulation of RIG-I signaling pathway innate immune response regulation of innate immune response negative regulation of innate immune response negative regulation of innate immune response metal ion binding defense response to virus antiviral innate immune response positive regulation of MDA-5 signaling pathway positive regulation of RIG-I signaling pathway	04622
1417460_at	Ifitm2	interferon induced transmembrane protein 2	7	-140954838	NM_030694	80876	34	immune system process molecular_function lysosome lysosomal membrane endosome plasma membrane plasma membrane response to virus membrane early endosome membrane late endosome membrane protein-containing complex response to type II interferon response to interferon-alpha response to interferon-beta negative regulation of viral genome replication innate immune response negative regulation of viral entry into host cell negative regulation of viral entry into host cell defense response to virus defense response to virus defense response to virus type I interferon-mediated signaling pathway
1449005_at	Slc16a3	solute carrier family 16 (monocarboxylic acid transporters), member 3	11	120948483, 120949066	NM_030696	80879	79	plasma membrane plasma membrane plasma membrane monocarboxylic acid transmembrane transporter activity lactate transmembrane transporter activity symporter activity lactate:proton symporter activity lactate:proton symporter activity monocarboxylic acid transport monocarboxylic acid transport membrane basolateral plasma membrane basolateral plasma membrane apical plasma membrane lateral plasma membrane transmembrane transporter activity protein catabolic process nuclear membrane lactate transmembrane transport plasma membrane lactate transport pyruvate catabolic process synapse pyruvate transmembrane transporter activity transmembrane transport parallel fiber to Purkinje cell synapse postsynaptic density membrane pyruvate transmembrane transport
1420591_at	Gpr84	G protein-coupled receptor 84	15	-103308234	NM_030720	80910	33	urotensin II receptor activity G protein-coupled receptor activity plasma membrane signal transduction G protein-coupled receptor signaling pathway neuropeptide signaling pathway membrane receptor complex
1456054_a_at	Pum1	pumilio RNA-binding family member 1	4	130663320, 130663356	BB314559	80912	61	P-body RNA binding mRNA 3'-UTR binding mRNA 3'-UTR binding mRNA 3'-UTR binding nucleoplasm cytoplasm cytoplasm cytosol cytosol regulation of translation spermatogenesis adult locomotory behavior cytoplasmic stress granule post-transcriptional regulation of gene expression post-transcriptional regulation of gene expression post-transcriptional gene silencing cell differentiation axon miRNA processing miRNA processing miRNA binding regulation of mRNA stability regulation of mRNA stability stem cell differentiation regulation of cell cycle regulation of chromosome segregation mRNA destabilization positive regulation of RIG-I signaling pathway positive regulation of miRNA-mediated gene silencing
1421870_at	Trim44	tripartite motif-containing 44	2	-102300118	NM_020267	80985	22	positive regulation of cytokine-mediated signaling pathway positive regulation of defense response to virus by host cytoplasm cytoplasm zinc ion binding regulation of gene expression regulation of gene expression protein ubiquitination positive regulation of DNA-templated transcription metal ion binding protein stabilization protein stabilization ubiquitin protein ligase activity negative regulation of protein K48-linked ubiquitination positive regulation of non-canonical NF-kappaB signal transduction
1450350_a_at	Jdp2	Jun dimerization protein 2	12	85599415, 85600017, 85599104	NM_030887	81703	44	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA binding chromatin binding double-stranded DNA binding DNA-binding transcription factor activity protein binding nucleus nucleus nucleus chromatin remodeling regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cAMP response element binding protein homodimerization activity histone deacetylase binding leucine zipper domain binding protein-containing complex binding fat cell differentiation negative regulation of fat cell differentiation protein heterodimerization activity RNA polymerase II transcription regulator complex histone chaperone activity sequence-specific double-stranded DNA binding
1440818_s_at	Sf3b1	splicing factor 3b, subunit 1	1	-54985169	BB161546	81898	67	spliceosomal complex assembly spliceosomal complex assembly mRNA splicing, via spliceosome mRNA splicing, via spliceosome chromatin blastocyst formation chromatin binding RNA binding mRNA binding mRNA binding protein binding nucleus nucleus nucleus spliceosomal complex U2-type spliceosomal complex U2 snRNP U2 snRNP U12-type spliceosomal complex U12-type spliceosomal complex nucleolus chromatin remodeling mRNA processing RNA splicing anterior/posterior pattern specification nuclear matrix nuclear speck small nuclear ribonucleoprotein complex U11/U12 snRNP positive regulation of transcription by RNA polymerase I positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase III U2-type prespliceosome U2-type precatalytic spliceosome catalytic step 2 spliceosome catalytic step 2 spliceosome B-WICH complex splicing factor binding	03040
1421463_at	Siglece	sialic acid binding Ig-like lectin E	7	-43651069	AF329269	83382	55	protein binding plasma membrane phagocytosis, engulfment inflammatory response cell adhesion cell adhesion external side of plasma membrane membrane carbohydrate binding sialic acid binding sialic acid binding monosaccharide binding negative regulation of inflammatory response negative regulation of phagocytosis, engulfment negative regulation of phagocytosis, engulfment
1449220_at	Gimap3	GTPase, IMAP family member 3	6	-48764463	NM_031247	83408	20	mitochondrial genome maintenance nucleotide binding temperature homeostasis positive regulation of natural killer cell cytokine production positive regulation of humoral immune response mediated by circulating immunoglobulin protein binding GTP binding mitochondrion mitochondrial outer membrane endoplasmic reticulum positive regulation of calcium ion transport into cytosol membrane negative regulation of type II interferon production positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation myeloid dendritic cell differentiation T cell homeostasis negative regulation of apoptotic process negative regulation of nitric oxide biosynthetic process positive regulation of gamma-delta T cell differentiation positive regulation of membrane potential positive regulation of natural killer cell mediated cytotoxicity regulation of mitochondrial membrane permeability negative regulation of T cell activation negative regulation of lipid catabolic process
1438069_a_at	Rbm5	RNA binding motif protein 5	9	-107740494	BE446879	83486	34	spliceosomal complex assembly regulation of alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome nucleic acid binding RNA binding RNA binding mRNA binding nucleus nucleus nucleoplasm spliceosomal complex mRNA processing apoptotic process RNA splicing positive regulation of apoptotic process metal ion binding
1437752_at	Lin28a	lin-28 homolog A	4	-134003329	BB706377	83557	153	P-body G-quadruplex RNA binding nucleic acid binding RNA binding RNA binding mRNA binding mRNA binding protein binding nucleus nucleus nucleolus nucleolus cytoplasm cytoplasm cytoplasm endoplasmic reticulum rough endoplasmic reticulum cytosol germ cell development germ cell development zinc ion binding cytoplasmic stress granule miRNA metabolic process miRNA catabolic process miRNA catabolic process miRNA catabolic process negative regulation of translation stem cell population maintenance regulatory ncRNA-mediated gene silencing pre-miRNA processing pre-miRNA processing pre-miRNA processing pre-miRNA processing RNA 3'-end processing translation initiation factor binding positive regulation of TOR signaling miRNA binding positive regulation of neuron differentiation negative regulation of glial cell differentiation positive regulation of translation metal ion binding stem cell differentiation positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction regulation of miRNA-mediated gene silencing pre-miRNA binding RNA 3' uridylation cellular response to glucose stimulus protein-RNA adaptor activity positive regulation of cell proliferation involved in kidney development polysome binding sequence-specific mRNA binding negative regulation of pre-miRNA processing positive regulation of cytoplasmic translation
1455940_x_at	Wdr6	WD repeat domain 6	9	-108572310	BB453609	83669	22	tRNA binding wobble position ribose methylation cytoplasm cytoplasm cytosol plasma membrane cell cycle tRNA processing COP9 signalosome negative regulation of cell population proliferation negative regulation of autophagy enzyme regulator activity tRNA methylation protein-containing complex insulin receptor substrate binding G1 to G0 transition
1424711_at	Cemip2	cell migration inducing hyaluronidase 2	19	21778339	BC019745	83921	37	angiogenesis hyalurononglucosaminidase activity calcium ion binding nucleolus cytosol plasma membrane multicellular organism development metabolic process membrane hydrolase activity hydrolase activity, acting on glycosyl bonds hyaluronan catabolic process carbohydrate binding intracellular membrane-bounded organelle
1419226_at	Cd96	CD96 antigen	16	-46035656	NM_032465	84544	21	natural killer cell cytokine production cytokine production involved in inflammatory response negative regulation of natural killer cell cytokine production protein binding cytoplasm inflammatory response cell adhesion cell-matrix adhesion cell-matrix adhesion membrane response to lipopolysaccharide negative regulation of type II interferon production
1456426_at	Clec2i	C-type lectin domain family 2, member i	6	128887586, 128887589	BE686253	93675	22	membrane raft assembly transmembrane signaling receptor activity protein binding endoplasmic reticulum plasma membrane external side of plasma membrane external side of plasma membrane cell surface cell surface membrane carbohydrate binding regulation of actin filament polymerization regulation of interleukin-2 production regulation of T cell proliferation receptor clustering negative regulation of osteoclast differentiation natural killer cell lectin-like receptor binding natural killer cell lectin-like receptor binding natural killer cell lectin-like receptor binding T cell receptor signaling pathway positive regulation of immunological synapse formation
1455778_at	Zkscan8	zinc finger with KRAB and SCAN domains 8	13	-21526419, -21513220	AW208912	93681	22	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific regulation of transcription by RNA polymerase II
1426536_at	Ice2	interactor of little elongation complex ELL subunit 2	9	69397997	BE952805	93697	18	euchromatin nucleus nucleoplasm cytosol transcription elongation factor complex Cajal body nuclear body histone locus body snRNA transcription by RNA polymerase II snRNA transcription by RNA polymerase II snRNA transcription by RNA polymerase III snRNA transcription by RNA polymerase III positive regulation of transcription by RNA polymerase III positive regulation of transcription by RNA polymerase III
1425295_at	Rnase2a	ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin)	14	-51255261	BC020070	93726	12	innate immune response in mucosa RNA nuclease activity RNA nuclease activity RNA nuclease activity extracellular space extracellular space chemotaxis defense response to Gram-positive bacterium
1418640_at	Sirt1	sirtuin 1	10	-63319004	NM_019812	93759	1263	single strand break repair negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II rDNA heterochromatin formation pyrimidine dimer repair by nucleotide-excision repair pyrimidine dimer repair by nucleotide-excision repair DNA synthesis involved in DNA repair chromatin chromatin euchromatin heterochromatin heterochromatin RNA polymerase II cis-regulatory region sequence-specific DNA binding angiogenesis angiogenesis ovulation from ovarian follicle fibrillar center intracellular glucose homeostasis positive regulation of protein phosphorylation positive regulation of endothelial cell proliferation p53 binding p53 binding p53 binding positive regulation of adaptive immune response transcription coactivator activity transcription corepressor activity transcription corepressor activity transcription corepressor activity histone deacetylase activity protein binding nucleus nucleus nucleus nuclear envelope nuclear inner membrane nuclear inner membrane nucleoplasm nucleoplasm nucleoplasm chromatin silencing complex cytoplasm mitochondrion mitochondrion cytosol chromatin organization chromatin remodeling protein deacetylation protein deacetylation protein deacetylation triglyceride mobilization apoptotic process DNA damage response response to oxidative stress transforming growth factor beta receptor signaling pathway multicellular organism development spermatogenesis regulation of mitotic cell cycle muscle organ development circadian rhythm positive regulation of cell population proliferation intrinsic apoptotic signaling pathway in response to DNA damage cellular response to starvation positive regulation of heart rate negative regulation of gene expression cardiac muscle cell apoptotic process negative regulation of cardiac muscle cell apoptotic process regulation of centrosome duplication negative regulation of triglyceride biosynthetic process positive regulation of cholesterol efflux regulation of lipid storage regulation of glucose metabolic process positive regulation of neuron projection development positive regulation of skeletal muscle cell proliferation positive regulation of macroautophagy positive regulation of macroautophagy protein ubiquitination PML body transferase activity nuclear receptor binding NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity NAD-dependent histone deacetylase activity peptidyl-lysine acetylation deacetylase activity deacetylase activity enzyme binding enzyme binding protein domain specific binding cell differentiation macrophage differentiation axon growth cone negative regulation of transforming growth factor beta receptor signaling pathway negative regulation of prostaglandin biosynthetic process heterochromatin formation heterochromatin formation protein destabilization negative regulation of TOR signaling negative regulation of TOR signaling NAD-dependent histone H3K14 deacetylase activity regulation of endodeoxyribonuclease activity negative regulation of NF-kappaB transcription factor activity negative regulation of tumor necrosis factor production response to insulin circadian regulation of gene expression circadian regulation of gene expression protein-containing complex leptin-mediated signaling pathway rDNA heterochromatin rDNA heterochromatin protein lysine deacetylase activity protein lysine deacetylase activity protein lysine deacetylase activity regulation of smooth muscle cell apoptotic process NAD-dependent protein deacetylase activity NAD-dependent protein deacetylase activity NAD-dependent protein deacetylase activity ESC/E(Z) complex intracellular triglyceride homeostasis regulation of peroxisome proliferator activated receptor signaling pathway positive regulation of insulin secretion involved in cellular response to glucose stimulus regulation of cell population proliferation cellular response to glucose starvation vasodilation negative regulation of phosphorylation negative regulation of phosphorylation histone binding response to hydrogen peroxide behavioral response to starvation cholesterol homeostasis intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator identical protein binding regulation of apoptotic process positive regulation of apoptotic process positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of canonical NF-kappaB signal transduction proteasome-mediated ubiquitin-dependent protein catabolic process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process HLH domain binding protein kinase B binding bHLH transcription factor binding negative regulation of DNA-binding transcription factor activity negative regulation of DNA-binding transcription factor activity negative regulation of DNA damage response, signal transduction by p53 class mediator negative regulation of neuron apoptotic process negative regulation of neuron apoptotic process positive regulation of blood vessel endothelial cell migration response to leptin positive regulation of MHC class II biosynthetic process response to ethanol negative regulation of fat cell differentiation positive regulation of gluconeogenesis positive regulation of gluconeogenesis positive regulation of DNA repair positive regulation of angiogenesis negative regulation of cell cycle negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription negative regulation of DNA-templated transcription positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II regulation of transcription by glucose positive regulation of insulin receptor signaling pathway metal ion binding NAD-dependent histone H3K9 deacetylase activity NAD-dependent histone H3K9 deacetylase activity NAD-dependent histone H4K16 deacetylase activity rhythmic process white fat cell differentiation mitogen-activated protein kinase binding negative regulation of helicase activity positive regulation of smooth muscle cell differentiation neuron apoptotic process maintenance of nucleus location positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction fatty acid homeostasis negative regulation of growth hormone secretion negative regulation of androgen receptor signaling pathway positive regulation of macrophage cytokine production positive regulation of cell growth involved in cardiac muscle cell development eNoSc complex cellular response to hydrogen peroxide NAD+ binding NAD+ binding lysine-acetylated histone binding regulation of bile acid biosynthetic process UV-damage excision repair cellular response to tumor necrosis factor cellular response to hypoxia cellular response to ionizing radiation regulation of protein serine/threonine kinase activity positive regulation of protein deacetylation regulation of brown fat cell differentiation stress-induced premature senescence energy homeostasis protein depropionylation protein-propionyllysine depropionylase activity DNA-binding transcription factor binding DNA repair-dependent chromatin remodeling histone H4K12 deacetylase activity histone H3K deacetylase activity NAD-dependent histone decrotonylase activity negative regulation of protein localization to nucleus negative regulation of protein acetylation negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway negative regulation of attachment of mitotic spindle microtubules to kinetochore negative regulation of reactive oxygen species biosynthetic process positive regulation of adipose tissue development cellular response to resveratrol cellular response to amyloid-beta keratin filament binding cellular response to leukemia inhibitory factor promoter-specific chromatin binding positive regulation of macrophage apoptotic process negative regulation of fibroblast apoptotic process negative regulation of cAMP-dependent protein kinase activity positive regulation of cAMP-dependent protein kinase activity positive regulation of cAMP-dependent protein kinase activity positive regulation of thyroid-stimulating hormone secretion negative regulation of cellular response to testosterone stimulus negative regulation of peptidyl-lysine acetylation negative regulation of cellular senescence positive regulation of cellular senescence positive regulation of double-strand break repair
1448709_at	Arid1a	AT-rich interaction domain 1A	4	-133679007, -133679007	NM_033566	93760	160	negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II chromatin chromatin chromatin formation of primary germ layer neural tube closure cardiac chamber development optic cup formation involved in camera-type eye development DNA binding protein binding nucleus nucleoplasm nucleoplasm chromatin organization nucleosome disassembly chromatin remodeling chromatin remodeling chromatin remodeling regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II gastrulation nervous system development embryo implantation SWI/SNF complex SWI/SNF complex SWI/SNF complex SWI/SNF complex nuclear receptor binding stem cell population maintenance regulation of mitotic metaphase/anaphase transition intracellular estrogen receptor signaling pathway androgen receptor signaling pathway forebrain development nucleosome binding nucleosome binding brahma complex glucocorticoid receptor signaling pathway positive regulation of T cell differentiation positive regulation of cell differentiation positive regulation of myoblast differentiation positive regulation of DNA-templated transcription positive regulation of DNA-templated transcription cardiac muscle cell differentiation placenta blood vessel development regulation of G0 to G1 transition SWI/SNF superfamily-type complex npBAF complex npBAF complex nBAF complex nBAF complex nBAF complex bBAF complex ATP-dependent chromatin remodeler activity positive regulation of stem cell population maintenance regulation of G1/S transition of mitotic cell cycle positive regulation of double-strand break repair regulation of nucleotide-excision repair
1421968_a_at	Nipa2	non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)	7	-55931265	NM_023647	93790	21	protein binding endosome early endosome plasma membrane plasma membrane monoatomic ion transport magnesium ion transmembrane transporter activity magnesium ion transport magnesium ion transport magnesium ion transport membrane membrane
1419006_s_at	Peli2	pellino 2	14	48120868	NM_033602	93834	25	protein polyubiquitination protein polyubiquitination positive regulation of protein phosphorylation protein binding cytosol regulation of Toll signaling pathway membrane transferase activity protein-macromolecule adaptor activity positive regulation of MAPK cascade ubiquitin protein ligase activity ubiquitin protein ligase activity
1427322_at	Brwd1	bromodomain and WD repeat domain containing 1	16	-96066667, -95992091, -96001547	BQ031260	93871	39	protein binding nucleus nucleus nucleus nucleoplasm nucleolus cytoplasm cytosol axoneme regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II cytoskeleton organization cytoskeleton organization regulation of cell shape regulation of cell shape motile cilium
1439352_at	Trim7	tripartite motif-containing 7	11	48826137, 48837470	BB825733	94089	24	nucleus nucleus cytoplasm cytoplasm cytoplasm Golgi apparatus zinc ion binding protein ubiquitination transferase activity metal ion binding defense response to virus ubiquitin protein ligase activity ubiquitin protein ligase activity antiviral innate immune response
1455189_at	Trim33	tripartite motif-containing 33	3	103279292	BB400432	94093	68	DNA binding protein binding nucleus nucleus nucleoplasm zinc ion binding gene expression protein ubiquitination transferase activity regulation of transforming growth factor beta receptor signaling pathway negative regulation of BMP signaling pathway metal ion binding ubiquitin protein ligase activity co-SMAD binding R-SMAD binding promoter-specific chromatin binding
1417665_a_at	Cpsf1	cleavage and polyadenylation specific factor 1	15	-76595807	NM_053193	94230	27	nucleic acid binding RNA binding nucleus nucleus nucleoplasm mRNA cleavage and polyadenylation specificity factor complex mRNA cleavage and polyadenylation specificity factor complex mRNA polyadenylation mRNA processing enzyme binding mRNA 3'-UTR AU-rich region binding	03015
1435768_at	Arid4b	AT-rich interaction domain 4B	13	14063783	AV371758	94246	41	negative regulation of transcription by RNA polymerase II transcription cis-regulatory region binding DNA binding protein binding nucleus nucleus nucleoplasm mitochondrion cytosol DNA methylation chromatin organization regulation of transcription by RNA polymerase II transcription by RNA polymerase II spermatogenesis negative regulation of cell migration negative regulation of transforming growth factor beta receptor signaling pathway positive regulation of transcription by RNA polymerase II genomic imprinting establishment of Sertoli cell barrier negative regulation of stem cell population maintenance positive regulation of stem cell population maintenance
1459900_at	C79468	expressed sequence C79468	6		BQ086025	97294	1
1433475_a_at	Fam8a1	family with sequence similarity 8, member A1	13	46669476	BG075168	97863	15	Hrd1p ubiquitin ligase complex molecular_function biological_process
1416234_at	Lrrc59	leucine rich repeat containing 59	11	94629776	AW476171	98238	24	nucleus endoplasmic reticulum membrane mitochondrial nucleoid intracellular membrane-bounded organelle
1418998_at	Kmo	kynurenine 3-monooxygenase	1	175632192	NM_133809	98256	39	monooxygenase activity kynurenine 3-monooxygenase activity kynurenine 3-monooxygenase activity kynurenine 3-monooxygenase activity extracellular space mitochondrion mitochondrial outer membrane mitochondrial outer membrane mitochondrial inner membrane tryptophan catabolic process response to salt stress positive regulation of glutamate secretion membrane NAD(P)H oxidase H2O2-forming activity oxidoreductase activity pyridine nucleotide biosynthetic process NAD metabolic process quinolinate biosynthetic process kynurenic acid biosynthetic process flavin adenine dinucleotide binding kynurenine metabolic process kynurenine metabolic process kynurenine metabolic process FAD binding L-kynurenine metabolic process positive regulation of glutamate secretion, neurotransmission	00380 01100
1430165_at	Stk17b	serine/threonine kinase 17b (apoptosis-inducing)	1	-53755511	AI661948	98267	36	nucleotide binding protein kinase activity protein serine/threonine kinase activity protein serine/threonine kinase activity ATP binding nucleus nucleus nucleoplasm plasma membrane protein phosphorylation apoptotic process programmed cell death actin cytoskeleton membrane kinase activity phosphorylation transferase activity intracellular signal transduction intracellular signal transduction positive regulation of apoptotic process Flemming body positive regulation of fibroblast apoptotic process
1427208_at	Zfp451	zinc finger protein 451	1	-33761540, -33801959, -33761544	BC024435	98403	31	DNA-binding transcription factor activity, RNA polymerase II-specific DNA binding transcription corepressor activity transcription corepressor activity nucleus nucleus PML body transferase activity protein sumoylation protein sumoylation negative regulation of transforming growth factor beta receptor signaling pathway sequence-specific DNA binding metal ion binding negative regulation of transcription initiation by RNA polymerase II negative regulation of transcription initiation by RNA polymerase II SUMO ligase activity SUMO ligase activity transcription regulator inhibitor activity
1436999_at	Pid1	phosphotyrosine interaction domain containing 1	1	-84036292	AI504908	98496	33	negative regulation of protein phosphorylation protein binding cytoplasm cytoplasm cytoplasm mitochondrion organization positive regulation of gene expression regulation of cell population proliferation cellular response to leptin stimulus positive regulation of transcription by RNA polymerase II negative regulation of glucose import negative regulation of glucose import negative regulation of glucose import negative regulation of insulin receptor signaling pathway regulation of mitochondrial membrane potential positive regulation of fat cell proliferation cellular response to cytokine stimulus cellular response to interleukin-6 cellular response to tumor necrosis factor cellular response to fatty acid negative regulation of protein localization to plasma membrane regulation of reactive oxygen species metabolic process regulation of reactive oxygen species metabolic process positive regulation of reactive oxygen species metabolic process negative regulation of ATP biosynthetic process positive regulation of ATP biosynthetic process
1419907_s_at	Fcrla	Fc receptor-like A	1	-170917593	BB219290	98752	26	transmembrane signaling receptor activity protein binding cytoplasm immune response cell surface receptor signaling pathway external side of plasma membrane cell differentiation
1426894_s_at	Eeig1	estrogen-induced osteoclastogenesis regulator 1	2	32535358	BC023470	98952	19	molecular_function protein binding cellular_component nucleus cytoplasm biological_process membrane membrane raft positive regulation of osteoclast differentiation
1433878_at	Mrps26	mitochondrial ribosomal protein S26	2	130563756	AI648866	99045	22	nucleoplasm mitochondrion mitochondrion mitochondrial inner membrane mitochondrial small ribosomal subunit mitochondrial small ribosomal subunit ribosome mitochondrial translation ribonucleoprotein complex
1449628_s_at	Stard7	StAR related lipid transfer domain containing 7	2	127270228, 127270228, 127270228	AI852671	99138	27	myeloid dendritic cell activation cytoplasm mitochondrion inflammatory response lipid binding T-helper 2 cell cytokine production type 2 immune response establishment of skin barrier mucociliary clearance
1427946_s_at	Dpyd	dihydropyrimidine dehydrogenase	3	118562179	BC028831	99586	23	nucleotide binding uracil binding uracil binding iron ion binding cytoplasm cytosol cytosol cytosol purine nucleobase catabolic process pyrimidine nucleobase catabolic process pyrimidine nucleobase catabolic process thymine catabolic process thymine catabolic process uracil catabolic process uracil catabolic process thymidine catabolic process CMP catabolic process dCMP catabolic process response to nutrient circadian rhythm response to xenobiotic stimulus response to organic cyclic compound oxidoreductase activity oxidoreductase activity, acting on the CH-CH group of donors dihydropyrimidine dehydrogenase (NADP+) activity dihydropyrimidine dehydrogenase (NADP+) activity dihydropyrimidine dehydrogenase (NADP+) activity uracil metabolic process identical protein binding protein homodimerization activity UMP catabolic process dTMP catabolic process dUMP catabolic process metal ion binding NADP binding NADP binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding FAD binding	00240 00410 00770 00983 01100
1423555_a_at	Ifi44	interferon-induced protein 44	3	-151730922	BB329808	99899	19	molecular_function cytoplasm immune response response to bacterium

1351 Genes